Sensitivity and Specificity

Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Synonym
Sensitivity and Specificity

Synonym

Excerpt	Reference
"Differences in sensitivity and specificity are inconclusive, but indicate that the sensitivity of exercise testing is, at best, equivalent to dobutamine testing, while any increase in specificity with dobutamine testing, compared with exercise testing, would not be clinically significant."	( Johns, JP; Martin, TW; Seaworth, JF, 1992)
"Overall sensitivity and specificity are comparable between the sexes."	( Chaitman, BR; Kong, BA; Miller, DD; Shaw, L, 1992)
"EET sensitivity and specificity is comparable to previous observations in AMI not treated with thrombolytic therapy."	( Morselli, L; Noussan, P; Presbitero, P; Sclavo, M, 1991)
"If greater sensitivity and specificity are required, hybridization with 32P- or alkaline phosphatase-labeled oligonucleotide probes can be used."	( Bester, AJ; du Toit, R; van Helden, PD; van Zyl, J; Victor, T, 1991)
"Their analytic sensitivity and specificity are also important."	( Dab, W; Dor, F; Empereur-Bissonnet, P; Zmirou, D, 1999)
"Sensitivity and specificity are 65 and 89%, respectively."	( Buunk, G; Meinders, AE; van der Hoeven, JG, 1999)
"Very good sensitivity and specificity are necessary for this."	( Mathian, B; Pallant, A; Patricot, MC; Prost, L; Theodore, C, 2000)
"However, the sensitivity and specificity are not satisfactory."	( Huang, CC; Lin, CL; Peng, CH; Shueh, S; Yang, CW, 2003)
"For hCT the sensitivity and specificity are 0."	( Arenas de Pablo, A; Calero-García, R; García de Barajas, S; García-Lujan, R; Lopez-Encuentra, A; Maldonado, A; Martín de Nicolás, JL; Martín-Escribano, P; Martín-García, I; Pozo, MA; Pozo-Rodríguez, F; Sánchez-Nistal, MA, 2005)
"This level of sensitivity and specificity is concordant with that from the determination of M."	( Jang, H; Kang, SJ; Kim, C; Kim, SY; Park, YJ; Song, E; Yoo, J, 2006)
"Sensitivity and specificity are essential in order for a biomarker to be useful."	( McConnell, JP; Miller, VM; Redfield, MM, 2007)
"Sensitivity and specificity are excellent for a cowside test and higher than 2 commonly used chemical dipsticks (Ketostix and Ketolac)."	( Falkenberg, U; Forderung, D; Heuwieser, W; Iwersen, M; Voigtsberger, R, 2009)
"However, sensitivity and specificity are high and FDG-PET may have a role to play under particular circumstances."	( Heys, SD; Peare, R; Staff, RT, 2010)
"Sensitivity and specificity are also high in subgrouping and grading, including myxoid types."	( Albertini, U; Brach del Prever, AM; Brach del Prever, EM; Comandone, A; De Marchi, A; Faletti, C; Forni, M; Gino, GC; Linari, A; Piana, R; Pozza, S; Verga, L, 2010)
"Their sensitivity and specificity are not perfect and there is a need for additional diagnostic biomarkers for PC in cases that are difficult to diagnose on routine stained sections."	( Egevad, L; Häggarth, L; Hägglöf, C; Jaraj, SJ; Ostman, A; Pontén, F; Wester, K, 2011)
"R-fMRI sensitivity and specificity are high for localizing hand motor area and even equivalent or slightly higher compared with T-fMRI."	( Lu, JF; Mao, Y; Qiu, TM; Tang, WJ; Wu, JS; Yan, CG; Yao, CJ; Zhou, LF; Zhu, FP; Zhuang, DX, 2014)
"Sensitivity and specificity are 99."	( Braeth, S; Dietrich, JW; Frank, CU; Loos, U; Wanjura, D, 2015)
"The sensitivity and specificity are higher with 20 ng/L as the critical value."	( Fang, K; Han, S; Su, X; Zhao, R, 2015)
"Sensitivity and specificity are different between these parameters."	( Andersen, LW; Cocchi, MN; Donnino, MW; Lokhandwala, S; Nair, S; Patel, P, 2017)

Excerpt

Reference

"Differences in sensitivity and specificity are inconclusive, but indicate that the sensitivity of exercise testing is, at best, equivalent to dobutamine testing, while any increase in specificity with dobutamine testing, compared with exercise testing, would not be clinically significant."

( Johns, JP; Martin, TW; Seaworth, JF, 1992)

"Overall sensitivity and specificity are comparable between the sexes."

( Chaitman, BR; Kong, BA; Miller, DD; Shaw, L, 1992)

"EET sensitivity and specificity is comparable to previous observations in AMI not treated with thrombolytic therapy."

( Morselli, L; Noussan, P; Presbitero, P; Sclavo, M, 1991)

"If greater sensitivity and specificity are required, hybridization with 32P- or alkaline phosphatase-labeled oligonucleotide probes can be used."

( Bester, AJ; du Toit, R; van Helden, PD; van Zyl, J; Victor, T, 1991)

"Their analytic sensitivity and specificity are also important."

( Dab, W; Dor, F; Empereur-Bissonnet, P; Zmirou, D, 1999)

"Sensitivity and specificity are 65 and 89%, respectively."

( Buunk, G; Meinders, AE; van der Hoeven, JG, 1999)

"Very good sensitivity and specificity are necessary for this."

( Mathian, B; Pallant, A; Patricot, MC; Prost, L; Theodore, C, 2000)

"However, the sensitivity and specificity are not satisfactory."

( Huang, CC; Lin, CL; Peng, CH; Shueh, S; Yang, CW, 2003)

"For hCT the sensitivity and specificity are 0."

( Arenas de Pablo, A; Calero-García, R; García de Barajas, S; García-Lujan, R; Lopez-Encuentra, A; Maldonado, A; Martín de Nicolás, JL; Martín-Escribano, P; Martín-García, I; Pozo, MA; Pozo-Rodríguez, F; Sánchez-Nistal, MA, 2005)

"This level of sensitivity and specificity is concordant with that from the determination of M."

( Jang, H; Kang, SJ; Kim, C; Kim, SY; Park, YJ; Song, E; Yoo, J, 2006)

"Sensitivity and specificity are essential in order for a biomarker to be useful."

( McConnell, JP; Miller, VM; Redfield, MM, 2007)

"Sensitivity and specificity are excellent for a cowside test and higher than 2 commonly used chemical dipsticks (Ketostix and Ketolac)."

( Falkenberg, U; Forderung, D; Heuwieser, W; Iwersen, M; Voigtsberger, R, 2009)

"However, sensitivity and specificity are high and FDG-PET may have a role to play under particular circumstances."

( Heys, SD; Peare, R; Staff, RT, 2010)

"Sensitivity and specificity are also high in subgrouping and grading, including myxoid types."

( Albertini, U; Brach del Prever, AM; Brach del Prever, EM; Comandone, A; De Marchi, A; Faletti, C; Forni, M; Gino, GC; Linari, A; Piana, R; Pozza, S; Verga, L, 2010)

"Their sensitivity and specificity are not perfect and there is a need for additional diagnostic biomarkers for PC in cases that are difficult to diagnose on routine stained sections."

Excerpt	Reference
"However, variable sensitivity and specificity have been observed in various community based studies."	( Parashari, A; Singh, V, 2013)
"And once their sensitivity and specificity have been proved they could be used as biomarkers for PD, even in the early phases of the disease."	( Bandrés, S; Barrero, F; Durán, R; Ramírez, M; Vives, F, 2014)
"Optimization of sensitivity and specificity has been able to achieve the sensitivity and specificity values as 95."	( Chakravorty, N; Ghosh, A; Mukherjee, J, 2023)
"Optimization of sensitivity and specificity has been able to achieve the sensitivity and specificity values as 95."	( Chakravorty, N; Ghosh, A; Mukherjee, J, 2023)

Excerpt	Reference
"In this study we evaluated the pre-treatment sensitivity and specificity of these two markers in this setting."	( Grenier, J; Khemissa-Akouz, F; Kramar, A; Senesse, P; Ychou, M, 2001)
"pylori treatment."	( Blanco, S; Cuesta, MA; Domínguez, J; Fernández, G; Forné, M; Lacoma, A; Latorre, I; Molinos, S; Prat, C; Viver, JM, 2008)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	437 (0.48)	23.3326
1990's	16446 (18.13)	12.5806
2000's	43328 (47.78)	18.1394
2010's	27205 (30.00)	28.8240
2020's	3274 (3.61)	9.53

Sensitivity and Specificity

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Research

Studies (90,690)

Drugs Studied (10,516)

Protein Targets (6,339)