4-chloro-2-nitrophenol profile

4-Chloro-2-nitrophenol is a nitrophenol derivative with a chlorine atom at position 4 and a nitro group at position 2 on the phenol ring. It is a pale yellow solid at room temperature. It is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals, including herbicides, fungicides, and insecticides. 4-Chloro-2-nitrophenol is also used as a dye and a colorant in various industries. It is a known environmental contaminant and may pose risks to human health and the environment. The compound can be synthesized via various routes, including nitration of 4-chlorophenol or chlorination of 2-nitrophenol. Its effects on the environment are studied due to its potential to contaminate water sources and impact aquatic life. Research also focuses on its toxicity and potential health risks to humans.'

ID Source	ID
PubMed CID	6980
SCHEMBL ID	305611
MeSH ID	M0186881

Synonym
AC-16758
nsc-520345
nsc520345
phenol, 4-chloro-2-nitro-
2-nitro-4-chlorophenol
4-chloro-2-nitrophenol
89-64-5
inchi=1/c6h4clno3/c7-4-1-2-6(9)5(3-4)8(10)11/h1-3,9
4-chloro-2-nitrophenol, >=97.0%
C0228
AKOS000121398
einecs 201-927-5
unii-438lq62wnh
ai3-28527
nsc 520345
438lq62wnh ,
BP-13325
FT-0618040
AE-562/40191217
p-chloro-o-nitrophenol
4-chloro-6-nitrophenol
5-chloro-2-hydroxynitrobenzene
SCHEMBL305611
4-chloro-2-nitro-phenol
DTXSID4058996
W-100365
mfcd00007113
FS-4191
STL199170
Q27258630
EN300-21529
Z104500910

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (14.29)	18.2507
2000's	3 (21.43)	29.6817
2010's	9 (64.29)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (6.67%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	14 (93.33%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
ammonium hydroxide azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.	2.07	1	azane; gas molecular entity; mononuclear parent hydride	EC 3.5.1.4 (amidase) inhibitor; metabolite; mouse metabolite; neurotoxin; NMR chemical shift reference compound; nucleophilic reagent; refrigerant
chlorine chloride : A halide anion formed when chlorine picks up an electron to form an an anion.	2.49	2	halide anion; monoatomic chlorine	cofactor; Escherichia coli metabolite; human metabolite
hydrogen carbonate Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.. hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.	2.05	1	carbon oxoanion	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
nitrates Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.	2.05	1	monovalent inorganic anion; nitrogen oxoanion; reactive nitrogen species
4-chlorophenol 4-chlorophenol: used as a root canal irrigant. 4-chlorophenol : A monochlorophenol substituted at the pare position by a chlorine atom.	2.05	1	monochlorophenol
2-aminophenol [no description available]	2.07	1	aminophenol	bacterial metabolite
2,3,4,6-tetrachlorophenol 2,3,4,6-tetrachlorophenol: RN given refers to parent cpd; see also record for tetrachlorophenol with locants for chloro groups not specified. 2,3,4,6-tetrachlorophenol : A tetrachlorophenol in which the chlorines are located at positions 2, 3, 4, and 6.	2.76	3	tetrachlorophenol	xenobiotic metabolite
2-nitrophenol nitrophenol : Any member of the class of phenols or substituted phenols carrying at least 1 nitro group.	2.05	1	2-nitrophenols
2-amino-4-chlorophenol 2-amino-4-chlorophenol: causes contact dermititis	2.48	2
benzoxazoles 1,3-benzoxazole : A benzoxazole in which the benzene ring is fused to a 1,3-oxazole ring across positions 4 and 5.. benzoxazole : Compounds based on a fused 1,2- or 1,3-oxazole and benzene bicyclic ring skeleton.	2.77	3	1,3-benzoxazoles; mancude organic heterobicyclic parent
3-nitrophenol [no description available]	3.27	1	3-nitrophenols
2,6-dichloro-4-nitrophenol [no description available]	3.27	1
2-chloro-4-nitrophenol 2-chloro-4-nitrophenol: structure in first source	3.27	1
rhodamine 6g rhodamine 6G: RN given refers to HCl	2.07	1
titanium Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.	2.03	1	titanium group element atom
titanium dioxide titanium dioxide: used medically as protectant against externally caused irritation & sunlight; high concentrations of dust may cause irritation to respiratory tract; RN given refers to titanium oxide (TiO2); structure. titanium dioxide : A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.	2.03	1	titanium oxides	food colouring
hydroxyl radical Hydroxyl Radical: The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.	2.11	1	oxygen hydride; oxygen radical; reactive oxygen species
peroxymonosulfate peroxymonosulfate: oxidizing agent in prevention of tooth discoloration; RN given refers to ion(2-)	7.11	1	sulfur oxide; sulfur oxoanion
5-chloro-2-mercaptobenzothiazole [no description available]	2.07	1
2-chloro-4-nitrophenylmaltotrioside [no description available]	1.99	1
nitrophenols Nitrophenols: PHENOLS carrying nitro group substituents.	5.16	14

Condition	Indicated	Relationship Strength	Studies	Trials
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	0	1.99	1	0

4-chloro-2-nitrophenol

Cross-References

Synonyms (32)

Research

Studies (14)

Market Indicators

Research Demand Index: 39.04

Study Types