Proteins > serine-protein kinase ATM isoform a
Page last updated: 2024-08-07 19:55:34

serine-protein kinase ATM isoform a

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (190)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
pd 173074Homo sapiens (human)Potency39.810710
acridoneHomo sapiens (human)Potency17.782810
althiazideHomo sapiens (human)Potency39.810710
chlorpyrifosHomo sapiens (human)Potency39.810710
dichlorodiphenyl dichloroethyleneHomo sapiens (human)Potency39.810710
dipyridamoleHomo sapiens (human)Potency31.622810
ethacrynic acidHomo sapiens (human)Potency39.810710
fenofibrateHomo sapiens (human)Potency44.668410
harmalineHomo sapiens (human)Potency35.481310
heptachlorHomo sapiens (human)Potency39.810710
vitamin k 3Homo sapiens (human)Potency39.810710
mitotaneHomo sapiens (human)Potency28.183810
phloretinHomo sapiens (human)Potency28.183810
streptonigrinHomo sapiens (human)Potency5.982230
tetraethylammonium chlorideHomo sapiens (human)Potency25.118910
9,10-dimethyl-1,2-benzanthraceneHomo sapiens (human)Potency17.782810
methylene blueHomo sapiens (human)Potency13.025840
perthaneHomo sapiens (human)Potency31.622810
skatoleHomo sapiens (human)Potency35.481310
methyl n-methylanthranilateHomo sapiens (human)Potency31.622810
1-naphthylphenylamineHomo sapiens (human)Potency35.481310
uvitex swnHomo sapiens (human)Potency31.622810
n-isopropyl-n-phenyl-4-phenylenediamineHomo sapiens (human)Potency25.118910
diethylhexyladipateHomo sapiens (human)Potency25.118910
dimethoxyphenylethylamineHomo sapiens (human)Potency12.589310
fluorantheneHomo sapiens (human)Potency35.481310
hematoxylinHomo sapiens (human)Potency35.481310
2,3-dimethylphenolHomo sapiens (human)Potency6.309610
amitriptyline hydrochlorideHomo sapiens (human)Potency14.125410
6-aminoquinolineHomo sapiens (human)Potency3.162310
n-methylphenethylamineHomo sapiens (human)Potency31.622810
estradiol valerateHomo sapiens (human)Potency31.622810
4-[(2,4,6-triamino-5-pyrimidinyl)azo]benzoic acidHomo sapiens (human)Potency0.354810
1,2-dibromo-4-(1,2-dibromoethyl)cyclohexaneHomo sapiens (human)Potency22.387210
2-hydroxyjugloneHomo sapiens (human)Potency0.794310
isovelleralHomo sapiens (human)Potency21.831530
permethrinHomo sapiens (human)Potency39.810710
s-2678Homo sapiens (human)Potency19.518520
enoximoneHomo sapiens (human)Potency39.810710
ticlopidine hydrochlorideHomo sapiens (human)Potency28.183810
oxaceprolHomo sapiens (human)Potency28.183810
toxoflavinHomo sapiens (human)Potency0.891310
1-nitro-2,4-difluorobenzeneHomo sapiens (human)Potency23.982130
acecainide hydrochlorideHomo sapiens (human)Potency22.387210
secnidazoleHomo sapiens (human)Potency7.079510
hesperetinHomo sapiens (human)Potency39.810710
1-hydroxybenzotriazoleHomo sapiens (human)Potency1.258910
3,5-di-tert-butyl-1,2-benzoquinoneHomo sapiens (human)Potency6.309610
2-butyl-6-(butylamino)-1h-benzo(de)isoquinoline-1,3(2h)-dioneHomo sapiens (human)Potency28.183810
nipecotic acid amideHomo sapiens (human)Potency17.782810
coumarin 7Homo sapiens (human)Potency14.243830
4-methyl-N-(phenylmethyl)benzenesulfonamideHomo sapiens (human)Potency50.118710
zpckHomo sapiens (human)Potency11.220210
7-amino-4-trifluoromethylcoumarinHomo sapiens (human)Potency17.782810
gidazepamHomo sapiens (human)Potency39.810710
ng-nitroarginine methyl esterHomo sapiens (human)Potency22.387210
schizandrin aHomo sapiens (human)Potency19.952610
2-chloroacetoacetanilideHomo sapiens (human)Potency15.848910
8-(4-benzenesulfonylamino)quinolineHomo sapiens (human)Potency28.183810
enniatin bHomo sapiens (human)Potency31.622810
estradiol 3-benzoateHomo sapiens (human)Potency17.782810
N-tert-butyl-6-ethyl-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamineHomo sapiens (human)Potency17.782810
beta-indol-3-yl-glucosideHomo sapiens (human)Potency28.183810
1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanoneHomo sapiens (human)Potency44.668410
oxopurpureineHomo sapiens (human)Potency31.622810
1-(4-methyl-1,3-benzothiazol-2-yl)-3-[3-(methylthio)phenyl]ureaHomo sapiens (human)Potency3.548110
3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxylic acid ethyl esterHomo sapiens (human)Potency28.183810
sakuranetinHomo sapiens (human)Potency39.810710
3-(2-Methylpropanoyloxy)-8-(2-methylbutanoyloxy)-9,10-epoxy-p-mentha-1,3,5-trieneHomo sapiens (human)Potency31.622810
isomaltoseHomo sapiens (human)Potency39.810710
amiodarone hydrochlorideHomo sapiens (human)Potency35.481310
Saphenic acid methyl esterHomo sapiens (human)Potency17.782810
oleic acidHomo sapiens (human)Potency15.848910
isosafroleHomo sapiens (human)Potency10.000010
2'-hydroxychalconeHomo sapiens (human)Potency23.133920
N-(3H-benzimidazol-5-yl)-2-furancarboxamideHomo sapiens (human)Potency0.631010
1-[2-chloro-5-(trifluoromethyl)phenyl]sulfonylazepaneHomo sapiens (human)Potency25.118910
8-[2-(4-methoxyphenyl)-5-phenyl-7-pyrazolo[1,5-a]pyrimidinyl]-1,4-dioxa-8-azaspiro[4.5]decaneHomo sapiens (human)Potency22.387210
2-[[3-acetyl-1-[4-(dimethylamino)phenyl]-2-methyl-5-indolyl]oxy]acetamideHomo sapiens (human)Potency8.912510
2-[(2-cyclohexyl-4-quinazolinyl)thio]-N-(4-methyl-1,2,5-oxadiazol-3-yl)acetamideHomo sapiens (human)Potency5.011910
N-[4-(4-fluorophenyl)-2-thiazolyl]-2-[(4-methylphenyl)sulfonylamino]benzamideHomo sapiens (human)Potency3.162310
6,7-dimethoxy-2-(2-thiazolyl)-3H-isoindol-1-oneHomo sapiens (human)Potency39.810710
1-(3,4-dichlorophenyl)-2-[[4-(2-furanylmethyl)-5-(3-pyridinyl)-1,2,4-triazol-3-yl]thio]ethanoneHomo sapiens (human)Potency3.548110
N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamideHomo sapiens (human)Potency28.183810
2-[5-[(2,4-dichlorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)Potency3.162310
(4-chloro-5-hydroxy-3-benzofuranyl)-phenylmethanoneHomo sapiens (human)Potency0.707910
2-[[2-(3,5-dimethyl-1-pyrazolyl)-6,6-dimethyl-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-4-yl]thio]-N-(2-thiazolyl)acetamideHomo sapiens (human)Potency5.011910
5-(2-phenylethyl)-1,3,4-thiadiazol-2-amineHomo sapiens (human)Potency39.810710
4-methoxycinnamic acidHomo sapiens (human)Potency44.668410
2-[[oxo(phenoxy)methyl]amino]benzene-1,4-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency22.387210
1-methyl-4-[(4-methylphenyl)thio]-3-nitro-2-quinolinoneHomo sapiens (human)Potency10.000010
2-(dichloromethyl)-4-(ethylthio)-6-phenyl-1,3,5-triazineHomo sapiens (human)Potency19.952610
5-[2-(5-methoxycarbonyl-2-thiophenyl)butan-2-yl]-2-thiophenecarboxylic acid methyl esterHomo sapiens (human)Potency12.589310
2-[(7-ethyl-[1,3]dioxolo[4,5-g]quinolin-6-yl)thio]acetic acid propan-2-yl esterHomo sapiens (human)Potency19.952610
2-amino-9-ethyl-3-pyrido[2,3-b]indolecarboxylic acid ethyl esterHomo sapiens (human)Potency35.481310
lupitidineHomo sapiens (human)Potency3.981110
[2-(5-methyl-2-thiophenyl)-4-quinolinyl]-(1-pyrrolidinyl)methanoneHomo sapiens (human)Potency19.952610
4-tert-butyl-N-(4-methyl-3-nitrophenyl)benzamideHomo sapiens (human)Potency39.810710
2-(4-chlorophenyl)-4-propan-2-yloxyquinazolineHomo sapiens (human)Potency39.810710
3-(2-methoxyphenyl)-6-(3-nitrophenyl)-1,4-dihydropyrimidin-2-oneHomo sapiens (human)Potency3.548110
1-(2,3-dimethyl-1-indolyl)-2-(4-methyl-1-piperidinyl)ethanoneHomo sapiens (human)Potency39.810710
2-(3-methoxyphenyl)-4-propan-2-yloxyquinazolineHomo sapiens (human)Potency39.810710
2-[[(5-methyl-4-phenyl-1,2,4-triazol-3-yl)thio]methyl]benzonitrileHomo sapiens (human)Potency7.079510
N-[(1-ethyl-2-oxo-6-benzo[cd]indolyl)sulfonyl]-N-(4-methoxyphenyl)-3-pyridinecarboxamideHomo sapiens (human)Potency39.810710
8-[1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]-1,4-dioxa-8-azaspiro[4.5]decaneHomo sapiens (human)Potency39.810710
3-(2-chloro-6-fluorophenyl)-N-(3-fluoro-4-methylphenyl)-5-methyl-4-isoxazolecarboxamideHomo sapiens (human)Potency39.810710
5-bromo-N-[3-chloro-2-(1-pyrrolidinyl)phenyl]-2-furancarboxamideHomo sapiens (human)Potency31.622810
auraptenHomo sapiens (human)Potency22.387210
N-[2-[tert-butyl(methyl)amino]ethyl]-N-methyl-2,2-diphenylacetamideHomo sapiens (human)Potency39.810710
6-(4-hydroxyphenyl)-5-(4-methoxyphenyl)-1,3-dimethylpyrrolo[3,4-d]pyrimidine-2,4-dioneHomo sapiens (human)Potency31.622810
3-[(2-propoxyphenyl)methyl]-1,3-benzoxazol-2-oneHomo sapiens (human)Potency12.589310
5-methoxy-3-methyl-2-benzofurancarboxylic acid [2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl] esterHomo sapiens (human)Potency19.952610
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-quinolinecarboxamideHomo sapiens (human)Potency39.810710
N-[[3-chloro-2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]butanamideHomo sapiens (human)Potency28.183810
2-(2,4-dichloro-6-methylphenoxy)-N-(2-furanylmethyl)acetamideHomo sapiens (human)Potency15.848910
N-(5-methyl-2-phenyl-3-pyrazolyl)-2-phenoxyacetamideHomo sapiens (human)Potency39.810710
N-[2-(2-Methoxyphenoxy)ethyl]-2-oxo-1H-quinoline-4-carboxamideHomo sapiens (human)Potency39.810710
2-(4-methyl-1-piperidinyl)-N-[2-(phenylthio)phenyl]acetamideHomo sapiens (human)Potency39.810710
thioureaHomo sapiens (human)Potency2.238710
1-(3-chlorophenyl)biguanide hydrochlorideHomo sapiens (human)Potency39.810710
3-(methylthio)-5-[4-(trifluoromethyl)phenyl]-1H-1,2,4-triazoleHomo sapiens (human)Potency39.810710
2-[(7-chloro-4-quinazolinyl)oxy]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanoneHomo sapiens (human)Potency39.810710
1-(5-bicyclo[2.2.1]hept-2-enylmethyl)-4-[3-(trifluoromethyl)phenyl]piperazineHomo sapiens (human)Potency39.810710
4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1h-pyrazol-1-yl)benzenesulfonamideHomo sapiens (human)Potency25.118910
N-(2-methoxy-3-dibenzofuranyl)-2-oxolanecarboxamideHomo sapiens (human)Potency39.810710
5-[[[2-[[2-furanyl(oxo)methyl]amino]phenyl]-oxomethoxy]methyl]-3-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl esterHomo sapiens (human)Potency3.548110
u-11634Homo sapiens (human)Potency23.375420
3-(4-fluorophenyl)-5-(2-furanyl)-2-phenyl-3,4-dihydropyrazoleHomo sapiens (human)Potency100.000010
3,5-dimethyl-2,6-bis(4-methylphenyl)-4-piperidinoneHomo sapiens (human)Potency8.912510
2-[cyclopentyl-[1-oxo-2-(5-thiophen-2-yl-2-tetrazolyl)ethyl]amino]-N-(2-oxolanylmethyl)-2-thiophen-2-ylacetamideHomo sapiens (human)Potency31.622810
2-(2-methoxyphenyl)-1-oxo-N-[2-oxo-2-[4-(2-pyridinyl)-1-piperazinyl]ethyl]-4-isoquinolinecarboxamideHomo sapiens (human)Potency22.387210
4-(3,4-dimethoxyphenyl)-2-(1-piperidinyl)-6-(trifluoromethyl)pyrimidineHomo sapiens (human)Potency35.481310
1-cyclopentyl-N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-5-oxo-3-pyrrolidinecarboxamideHomo sapiens (human)Potency10.000010
N-ethyl-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(phenylmethyl)propanamideHomo sapiens (human)Potency15.848910
1-methyl-6-[(4-methyl-1-piperidinyl)sulfonyl]-3-[oxo(1-piperidinyl)methyl]-4-quinolinoneHomo sapiens (human)Potency4.466810
2-amino-7-methyl-4-(5-nitro-2-furanyl)-5-oxo-4H-pyrano[3,2-c]pyran-3-carbonitrileHomo sapiens (human)Potency31.622810
cgp 13501Homo sapiens (human)Potency39.810710
(S)-4',5,7-Trihydroxy-6-prenylflavanoneHomo sapiens (human)Potency1.000010
2-methyl-1-phenyl-5-benzimidazolecarboxylic acid [2-(2-methoxyanilino)-2-oxoethyl] esterHomo sapiens (human)Potency0.631010
ArteminHomo sapiens (human)Potency39.810710
1-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(2,4,6-trimethylphenyl)thioureaHomo sapiens (human)Potency25.118910
6-amino-3-methyl-4-(2-methylpropyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrileHomo sapiens (human)Potency39.810710
3-[[cyclopropyl(oxo)methyl]amino]-5-phenyl-2-thiophenecarboxylic acid methyl esterHomo sapiens (human)Potency35.481310
N-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-4-oxo-1-benzopyran-2-carboxamideHomo sapiens (human)Potency0.707910
1-(2,6-dimethylphenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]thioureaHomo sapiens (human)Potency17.782810
2-(3-oxo-2,4-dihydroquinoxalin-1-yl)-2-phenyl-N-(4-propan-2-ylphenyl)acetamideHomo sapiens (human)Potency35.481310
6-(2,3-dihydro-1,4-benzodioxin-3-yl)-3-(phenoxymethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleHomo sapiens (human)Potency0.707910
2-[4-(2,5-diphenyl-3,4-dihydropyrazol-3-yl)-2-methoxyphenoxy]acetic acidHomo sapiens (human)Potency35.481310
2-chloro-N-(2,6-dimethylphenyl)-3-oxo-3-phenylpropanamideHomo sapiens (human)Potency35.481310
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[[2-(2-pyridinyl)-1-benzimidazolyl]methyl]-1H-1,2,4-triazole-5-thioneHomo sapiens (human)Potency20.971520
2-(4-oxo-3-quinazolinyl)-N-[3-(1-piperidinylsulfonyl)phenyl]acetamideHomo sapiens (human)Potency0.631010
LSM-25964Homo sapiens (human)Potency39.810710
cgp 7930Homo sapiens (human)Potency39.810710
dibutyl maleateHomo sapiens (human)Potency31.622810
decaprenoic acidHomo sapiens (human)Potency39.810710
naftifine hydrochlorideHomo sapiens (human)Potency39.810710
hispidulinHomo sapiens (human)Potency25.118910
rottlerinHomo sapiens (human)Potency16.397420
ellagic acidHomo sapiens (human)Potency19.952610
xylometazoline hydrochlorideHomo sapiens (human)Potency22.387210
N-[2-(2,3,4-trimethoxyphenyl)ethyl]-2-pyrazolo[1,5-a]pyridinecarboxamideHomo sapiens (human)Potency22.387210
4-[1-[(4-methyl-2-oxo-1-benzopyran-7-yl)amino]-3-oxo-1H-isoindol-2-yl]-1-piperidinecarboxylic acid ethyl esterHomo sapiens (human)Potency39.810710
1-[2-(4-methylphenyl)ethyl]-N-[3-(4-methyl-1-piperazinyl)propyl]-5-oxo-3-pyrrolidinecarboxamideHomo sapiens (human)Potency39.810710
furazolidoneHomo sapiens (human)Potency22.387210
flavokawain bHomo sapiens (human)Potency28.183810
1,2-bis(2-pyridyl)ethyleneHomo sapiens (human)Potency0.316210
aurantiamineHomo sapiens (human)Potency39.810710
dithiazanine iodideHomo sapiens (human)Potency31.622810
LonchocarpinHomo sapiens (human)Potency25.956120
dihydroergotoxineHomo sapiens (human)Potency35.481310
chaetoglobosin AHomo sapiens (human)Potency39.810710
sb 222200Homo sapiens (human)Potency22.387210
(2R,4R)-2-[[4-(hydroxymethyl)phenyl]methoxy]-4-(4-oxo-1-benzopyran-3-yl)-3,4-dihydro-2H-pyran-6-carboxylic acid prop-2-enyl esterHomo sapiens (human)Potency10.000010
estradiol 17-acetateHomo sapiens (human)Potency39.810710
cgs 21680aHomo sapiens (human)Potency39.810710
macelignanHomo sapiens (human)Potency35.481310
2-methoxy-3-methyl-9H-carbazoleHomo sapiens (human)Potency17.782810
calcimycinHomo sapiens (human)Potency39.810710
4-[3-(3-fluorophenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamideHomo sapiens (human)Potency39.810710
2-diethylaminoethyl 4-nitrobenzoate hydrochlorideHomo sapiens (human)Potency35.481310
dehydrocurvularinHomo sapiens (human)Potency39.810710
malyngamide AHomo sapiens (human)Potency39.810710
18-Deoxy-portulideHomo sapiens (human)Potency19.952610
N-(5-chloro-2-pyridinyl)-4H-thieno[3,2-c][1]benzopyran-2-carboxamideHomo sapiens (human)Potency15.848910
4-methyl-N-(3-methylbutyl)-5-(5-methyl-3-phenyl-4H-isoxazol-5-yl)-2-thiazolecarboxamideHomo sapiens (human)Potency39.810710
(3R)-7-phenyl-2-(phenylmethyl)-3-[4-(trifluoromethyl)phenyl]-3a,6,7,7a-tetrahydro-3H-isoindol-1-oneHomo sapiens (human)Potency22.387210
(3S)-3-cyclopentyl-4-oxo-3-phenyldiazetidine-1,2-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency25.118910
5-(2-benzofuranyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidineHomo sapiens (human)Potency39.810710
ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylateHomo sapiens (human)Potency0.577420
3-(4-methoxyphenyl)-1-methyl-1H-1,2,4-triazol-5-olHomo sapiens (human)Potency6.309610