Compounds > 2,4,5,2',5'-pentachlorobiphenyl
Page last updated: 2024-09-22

2,4,5,2',5'-pentachlorobiphenyl

Cross-References

ID SourceID
PubMed CID37807
CHEMBL ID14041
SCHEMBL ID811509
MeSH IDM0054882

Synonyms (29)

Synonym
1,1'-biphenyl, 2,2',4,5,5'-pentachloro-
2,2',4,5,5'-pentachlorobiphenyl
inchi=1/c12h5cl5/c13-6-1-2-9(14)7(3-6)8-4-11(16)12(17)5-10(8)15/h1-5
37680-73-2
pcb 101
2,2',4,5,5'pentachlorobiphenyl
2,4,5,2',5'-pentachlorobiphenyl
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene
CHEMBL14041
2,4,5,2',5'-pentachloro-biphenyl
unii-803yvi5bnp
803yvi5bnp ,
pcb no 101
AKOS015903436
SCHEMBL811509
pcb-101
LAHWLEDBADHJGA-UHFFFAOYSA-N
2,2',4,5,5'-pentachloro-1,1'-biphenyl
DTXSID8038304 ,
pcb no 101, analytical standard
pcb no. 101 10 microg/ml in isooctane
pcb no. 101
pcb no. 101 100 microg/ml in ihexane
pcb no. 101 100 microg/ml in isooctane
k 101
cb 101; pcb 101
Q27269110
PD162576
dtxcid6018304

Bioassays (1)

Assay IDTitleYearJournalArticle
AID23673Partition coefficient (logP)2002Bioorganic & medicinal chemistry letters, Apr-08, Volume: 12, Issue:7
Novel estimation of lipophilic behaviour of polychlorinated biphenyls.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (49)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (2.04)18.7374
1990's3 (6.12)18.2507
2000's17 (34.69)29.6817
2010's24 (48.98)24.3611
2020's4 (8.16)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (2.04%)4.05%
Observational0 (0.00%)0.25%
Other48 (97.96%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
diphenyl[no description available]medium20aromatic fungicide;
benzenes;
biphenyls		antifungal agrochemical;
antimicrobial food preservative
4,4'-dichlorobiphenyl[no description available]medium10dichlorobiphenyl;
monochlorobenzenes
decachlorobiphenyl[no description available]medium10pentachlorobenzenes;
polychlorobiphenyl
4-chlorobiphenyl[no description available]medium10monochlorobiphenyl
2,2'-dichlorobiphenyl[no description available]medium10
3,4,5,3',4',5'-hexachlorobiphenyl[no description available]medium20hexachlorobiphenyl;
trichlorobenzene
2,3,4,5-tetrachlorobiphenyl[no description available]medium10tetrachlorobenzene;
tetrachlorobiphenyl
2,4,5,2',4',5'-hexachlorobiphenyl[no description available]medium150hexachlorobiphenyl
2,5,2',5'-tetrachlorobiphenyl[no description available]medium70dichlorobenzene;
tetrachlorobiphenyl
2,2',5-trichlorobiphenyl[no description available]medium10
3,4,5,3',4'-pentachlorobiphenyl[no description available]medium20pentachlorobiphenyl;
trichlorobenzene
2,4,4'-trichlorobiphenyl[no description available]medium100
2,2',3',4,4',5-hexachlorobiphenyl[no description available]medium70polychlorobiphenyl
pcb 180[no description available]medium50polychlorobiphenyl
ddt[no description available]medium40benzenoid aromatic compound;
chlorophenylethane;
monochlorobenzenes;
organochlorine insecticide		bridged diphenyl acaricide;
carcinogenic agent;
endocrine disruptor;
persistent organic pollutant
pcb 118[no description available]medium80dichlorobenzene;
pentachlorobiphenyl;
trichlorobenzene
dichlorodiphenyl dichloroethylene[no description available]medium30chlorophenylethylene;
monochlorobenzenes		human xenobiotic metabolite;
persistent organic pollutant
hexachlorocyclohexane[no description available]medium40chlorocyclohexane
benzofurans[no description available]medium10
malondialdehyde[no description available]medium10dialdehydebiomarker
heptachlor epoxide[no description available]medium10oxanes
heptachlor[no description available]medium10cyclodiene organochlorine insecticideagrochemical;
antibacterial agent;
antifungal agent;
GABA-gated chloride channel antagonist;
persistent organic pollutant
titanium[no description available]medium10titanium group element atom
titanium dioxide[no description available]medium10titanium oxidesfood colouring
endosulfan[no description available]medium10cyclic sulfite ester;
cyclodiene organochlorine insecticide		acaricide;
agrochemical;
GABA-gated chloride channel antagonist;
persistent organic pollutant
palladium[no description available]medium20metal allergen;
nickel group element atom;
platinum group metal atom
cadmium[no description available]medium10cadmium molecular entity;
zinc group element atom
phenylisothiocyanate[no description available]medium10isothiocyanateallergen;
reagent
aluminum oxide[no description available]medium10
2,3,4,4'5-pentachlorobiphenyl[no description available]medium10monochlorobenzenes;
pentachlorobiphenyl;
tetrachlorobenzene
2,3,4,2',3',4'-hexachlorobiphenyl[no description available]medium10
hexachlorobenzene[no description available]medium20aromatic fungicide;
chlorobenzenes		antifungal agrochemical;
carcinogenic agent;
persistent organic pollutant
thyroxine[no description available]medium402-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
2,2',3,5',6-pentachlorobiphenyl[no description available]medium20
pentachlorophenol[no description available]medium10aromatic fungicide;
chlorophenol;
organochlorine pesticide;
pentachlorobenzenes		human xenobiotic metabolite
methylsulfonylpentachlorobenzene[no description available]medium10
3,4,3',4'-tetrachlorobiphenyl[no description available]medium20dichlorobenzene;
tetrachlorobiphenyl
chlorodiphenyl (54% chlorine)[no description available]medium10
diethylnitrosamine[no description available]medium10nitrosaminecarcinogenic agent;
hepatotoxic agent;
mutagen
5-acetylamino-6-formylamino-3-methyluracil[no description available]medium10formamidopyrimidinemouse metabolite
1-methyluric acid[no description available]medium10oxopurinehuman xenobiotic metabolite;
mouse metabolite
1,7-dimethyluric acid[no description available]medium10oxopurinehuman xenobiotic metabolite;
mouse metabolite
uric acid[no description available]medium10uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
uracil[no description available]medium10pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
caffeine[no description available]medium10purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
1-methylxanthine[no description available]medium101-methylxanthinemouse metabolite
cb 149[no description available]medium10
triiodothyronine[no description available]medium102-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
3,3'-dichlorobiphenyl[no description available]medium10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine[no description available]medium102-acetyl-1-alkyl-sn-glycero-3-phosphocholineantihypertensive agent;
beta-adrenergic antagonist;
bronchoconstrictor agent;
hematologic agent;
vasodilator agent
12-hydroxy-5,8,10,14-eicosatetraenoic acid[no description available]medium10
ConditionIndicatedRelationship StrengthStudiesTrials
Body Weight0low10
Breast Cancer0low20
Breast Carcinoma0low20
Breast Neoplasms0low20
Breast Tumors0low20
Cancer of Breast0low20
Cancer of the Breast0low20
Delayed Effects, Prenatal Exposure0low10
Diabetes Mellitus0low10
Hormone-Dependent Neoplasms0low10
Human Mammary Carcinoma0low20
Late Effects, Prenatal Exposure0low10
Malignant Neoplasm of Breast0low20
Malignant Tumor of Breast0low20
Mammary Cancer0low20
Mammary Carcinoma, Human0low20
Mammary Neoplasm, Human0low20
Mammary Neoplasms, Human0low20
Neoplasms, Breast0low20
Neoplasms, Hormone-Dependent0low10
Pregnancy0low10
Prenatal Exposure Delayed Effects0low10
Sensitivity and Specificity0low10
Tumors, Breast0low20

Research Highlights

Safety/Toxicity (2)

ArticleYear
Effects of polychlorinated biphenyls in CD-1 mice: reproductive toxicity and intergenerational transmission.
Toxicological sciences : an official journal of the Society of Toxicology, Volume: 126, Issue: 1		2012
Genotoxic effects of polychlorinated biphenyls (PCB 153, 138, 101, 118) in a fish cell line (RTG-2).
Toxicology in vitro : an international journal published in association with BIBRA, Volume: 25, Issue: 5		2011
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (6)

ArticleYear
Telomerase gene expression bioassays indicate metabolic activation of genotoxic lower chlorinated polychlorinated biphenyls.
Scientific reports, 11-15, Volume: 8, Issue: 1		2018
Hormetic effects of noncoplanar PCB exposed to human lung fibroblast cells (HELF) and possible role of oxidative stress.
Environmental toxicology, Volume: 30, Issue: 12		2015
Vertical distribution of AhR-activating compounds in sediments contaminated by modernized pulp and paper industry.
Water research, Mar-01, Volume: 50		2014
Degradation of pentachlorobiphenyl by a sequential treatment using Pd coated iron and an aerobic bacterium (H1).
Chemosphere, Volume: 76, Issue: 11		2009
Catalytic dechlorination of polychlorinated biphenyls in soil by palladium-iron bimetallic catalyst.
Journal of hazardous materials, May-15, Volume: 164, Issue: 1		2009
2,2',4,5,5'-Pentachlorobiphenyl: comparative metabolism in mink (Mustela vison) and mouse.
Chemical research in toxicology, Volume: 9, Issue: 8		1996
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]