| ID Source | ID |
|---|---|
| PubMed CID | 93460 |
| CHEBI ID | 38876 |
| SCHEMBL ID | 119518 |
| MeSH ID | M0189786 |
| Synonym |
|---|
| tia 230 |
| (rs)-o-1-(4-chlorophenyl)pyrazol-4-yl o-ethyl s-propyl phosphorothioate |
| phosphorothioic acid, o-(1-(4-chlorophenyl)-1h-pyrazol-4-yl) o-ethyl s-propyl ester, (+-)- |
| (+-)-o-(1-(4-chlorophenyl)-1h-pyrazol-4-yl) o-ethyl s-propyl phosphorothioate |
| o-(1-(4-chlorophenyl)-1h-pyrazol-4-yl) o-ethyl s-propyl phosphorothioate |
| pyraclofos [iso] |
| (rs)-(o-1-(4-chlorophenyl)pyrazol-4-yl-o-ethyl-s-propylphosphorothioate) (iupac) |
| CHEBI:38876 |
| boltage |
| o-[1-(4-chlorophenyl)-1h-pyrazol-4-yl] o-ethyl s-propyl thiophosphate |
| o-[1-(4-chlorophenyl)-1h-pyrazol-4-yl] o-ethyl s-propyl phosphorothioate |
| pyraclofos |
| 89784-60-1 |
| voltage |
| phosphorothioic acid, o-(1-(4-chlorophenyl)-1h-pyrazol-4-yl) o-ethyl s-propyl ester |
| starlet |
| inchi=1/c14h18cln2o3ps/c1-3-9-22-21(18,19-4-2)20-14-10-16-17(11-14)13-7-5-12(15)6-8-13/h5-8,10-11h,3-4,9h2,1-2h3 |
| qhgvxilfmxydrs-uhfffaoysa- |
| 1-(4-chlorophenyl)-4-(ethoxy-propylsulfanylphosphoryl)oxypyrazole |
| 1-(4-chlorophenyl)-4-[ethoxy(propylsulfanyl)phosphoryl]oxypyrazole |
| 77458-01-6 |
| C18406 |
| m0w5lec929 , |
| unii-m0w5lec929 |
| FT-0602978 |
| phosphorothioic acid, o-[1-(4-chlorophenyl)-1h-pyrazol-4-yl] o-ethyl s-propyl ester |
| SCHEMBL119518 |
| (rs)-(o-1-(4-chlorophenyl)pyrazol-4-yl o-ethyl s-propyl phosphorothioate) |
| DTXSID4058493 |
| thiophosphoric acid, o-[1-(4-chlorophenyl)-1h-pyrazol-4-yl] ester, o,-ethyl ester, s-propyl ester |
| 1-(4-chlorophenyl)-4-(ethoxy-propylsulfanyl-phosphoryl)oxy-pyrazole |
| QHGVXILFMXYDRS-UHFFFAOYSA-N |
| pyraclofos 10 microg/ml in cyclohexane |
| o-1-(4-chlorophenyl)-1h-pyrazol-4-yl o-ethyl s-propyl phosphorothioate |
| Q27118010 |
(+)-pyraclofos was about 6 times more toxic than its antipode. (R)-Pyracl ofos was consistently more toxic to zebrafish than (S-Pyrclofos)
| Excerpt | Reference | Relevance |
|---|---|---|
| " However, acute aquatic assays suggested that (+)-pyraclofos was about 6 times more toxic than its antipode." | ( Enantiomeric separation and toxicity of an organophosporus insecticide, pyraclofos. Chen, S; Zhang, H; Zhou, S, 2012) | 0.86 |
| " (R)-Pyraclofos was consistently more toxic than (S)-Pyraclofos for the acute toxicity, developmental toxicity and immunotoxicity to zebrafish." | ( Enantioselective developmental toxicity and immunotoxicity of pyraclofos toward zebrafish (Danio rerio). Bao, L; Xu, C; Zhang, H; Zhang, W; Zhang, Z; Zhuang, S, 2015) | 1.17 |
The tips of the villi were necrotic in the high dosage groups. We suggest that pyraclofos and tebufenpyrad could be used efficiently on perilla leaves.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The tips of the villi were necrotic in the high dosage groups of isazofos- and pyraclofos-treated quail." | ( Risk assessment of the organophosphate pesticides isazofos and pyraclofos using a 21-day dietary toxicity study in Japanese quail. Bae, BK; Cho, SA; Kim, DJ; Park, JH; Seok, SH, 2008) | 0.81 |
| " We suggest that pyraclofos and tebufenpyrad could be used efficiently on perilla leaves under the recommended dosage conditions." | ( A QuEChERS-based extraction method for the residual analysis of pyraclofos and tebufenpyrad in perilla leaves using gas chromatography: application to dissipation pattern. Abd El-Aty, AM; Al Mahmud, MN; Na, TW; Nahar, N; Park, JH; Park, KH; Rahman, M; Shim, JH; Yang, A, 2013) | 0.97 |
| Role | Description |
|---|---|
| EC 3.1.1.7 (acetylcholinesterase) inhibitor | An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. |
| agrochemical | An agrochemical is a substance that is used in agriculture or horticulture. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| organic thiophosphate | |
| organothiophosphate insecticide | |
| organochlorine insecticide | Any organochlorine pesticide that has been used as an insecticide. |
| pyrazoles | |
| monochlorobenzenes | Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine. |
| organosulfur compound | An organosulfur compound is a compound containing at least one carbon-sulfur bond. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (22.81) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (9.09%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (90.91%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||