Proteins > serine/threonine-protein kinase mTOR isoform 1
Page last updated: 2024-08-07 18:24:29

serine/threonine-protein kinase mTOR isoform 1

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (260)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
quinacrineHomo sapiens (human)Potency18.946340
catecholHomo sapiens (human)Potency11.535630
hydroquinoneHomo sapiens (human)Potency17.553130
spermidineHomo sapiens (human)Potency24.701320
sk&f 81297Homo sapiens (human)Potency26.121610
sk&f 82958Homo sapiens (human)Potency18.985020
octoclothepineHomo sapiens (human)Potency21.778330
sk&f 77434Homo sapiens (human)Potency23.280910
1,10-phenanthrolineHomo sapiens (human)Potency2.345820
1-(1-naphthyl)piperazineHomo sapiens (human)Potency16.481610
3,4-dichloroisocoumarinHomo sapiens (human)Potency21.094240
mdl 72222Homo sapiens (human)Potency13.091810
4-amino-1,8-naphthalimideHomo sapiens (human)Potency14.689210
4-diphenylacetoxy-1,1-dimethylpiperidiniumHomo sapiens (human)Potency2.074910
6-nitroso-1,2-benzopyroneHomo sapiens (human)Potency18.036140
N-(2-aminoethyl)-5-chloro-1-naphthalenesulfonamideHomo sapiens (human)Potency21.301620
aa 861Homo sapiens (human)Potency19.606720
3-(2'-aminobenzhydryloxy)tropaneHomo sapiens (human)Potency18.492710
amiodaroneHomo sapiens (human)Potency19.606720
amitriptylineHomo sapiens (human)Potency14.689220
amoxapineHomo sapiens (human)Potency24.227830
amsacrineHomo sapiens (human)Potency1.447330
aprindineHomo sapiens (human)Potency20.886820
benserazideHomo sapiens (human)Potency24.701320
calmidazoliumHomo sapiens (human)Potency21.014530
cantharidinHomo sapiens (human)Potency13.681040
carvedilolHomo sapiens (human)Potency14.689220
cgs 15943Homo sapiens (human)Potency13.009930
chelerythrineHomo sapiens (human)Potency2.930910
chlorpromazineHomo sapiens (human)Potency21.301620
clemastineHomo sapiens (human)Potency20.405420
clomipramineHomo sapiens (human)Potency20.405420
cyclobenzaprineHomo sapiens (human)Potency21.301620
cyproheptadineHomo sapiens (human)Potency26.121610
dephostatinHomo sapiens (human)Potency16.750530
dequaliniumHomo sapiens (human)Potency12.927420
desipramineHomo sapiens (human)Potency20.405420
diphenyleneiodoniumHomo sapiens (human)Potency4.968840
disulfiramHomo sapiens (human)Potency0.736030
2,3-dimethoxy-1,4-naphthoquinoneHomo sapiens (human)Potency22.310830
domperidoneHomo sapiens (human)Potency16.481610
doxazosinHomo sapiens (human)Potency18.894920
ebastineHomo sapiens (human)Potency13.630840
ebselenHomo sapiens (human)Potency20.405420
ellipticineHomo sapiens (human)Potency21.778330
felodipineHomo sapiens (human)Potency20.749110
fenofibrateHomo sapiens (human)Potency13.091810
fluphenazineHomo sapiens (human)Potency19.881240
fluorouracilHomo sapiens (human)Potency23.280910
fluoxetineHomo sapiens (human)Potency22.631730
fluspirileneHomo sapiens (human)Potency21.597040
vanoxerineHomo sapiens (human)Potency19.897240
gbr 12935Homo sapiens (human)Potency14.689220
gossypolHomo sapiens (human)Potency14.528040
1-(5-isoquinolinesulfonyl)-2-methylpiperazineHomo sapiens (human)Potency16.840020
haloperidolHomo sapiens (human)Potency23.280920
4-fluorohexahydrosiladifenidolHomo sapiens (human)Potency23.280920
tele-methylhistamineHomo sapiens (human)Potency3.288510
ifenprodilHomo sapiens (human)Potency11.033720
imipramineHomo sapiens (human)Potency9.950620
indirubin-3'-monoximeHomo sapiens (human)Potency3.288510
indomethacinHomo sapiens (human)Potency4.645110
isoproterenolHomo sapiens (human)Potency15.792220
1-(2-naphthalenyl)-3-[(phenylmethyl)-propan-2-ylamino]-1-propanoneHomo sapiens (human)Potency16.960530
nsc 664704Homo sapiens (human)Potency16.511130
beta-lapachoneHomo sapiens (human)Potency19.606720
loperamideHomo sapiens (human)Potency17.142540
loratadineHomo sapiens (human)Potency23.280910
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-oneHomo sapiens (human)Potency4.504340
maprotilineHomo sapiens (human)Potency17.588130
memantineHomo sapiens (human)Potency6.561410
methiothepinHomo sapiens (human)Potency19.767830
nocodazoleHomo sapiens (human)Potency0.119820
mitoxantroneHomo sapiens (human)Potency0.146910
ml 7Homo sapiens (human)Potency22.307220
naftopidilHomo sapiens (human)Potency24.227830
nicardipineHomo sapiens (human)Potency21.597040
niclosamideHomo sapiens (human)Potency1.620820
nifedipineHomo sapiens (human)Potency16.481610
nitrendipineHomo sapiens (human)Potency19.606720
nortriptylineHomo sapiens (human)Potency23.991140
4-(2'-methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazineHomo sapiens (human)Potency14.526220
pd 169316Homo sapiens (human)Potency5.838220
perphenazineHomo sapiens (human)Potency19.868430
prazosinHomo sapiens (human)Potency16.591020
proadifenHomo sapiens (human)Potency14.689210
prochlorperazineHomo sapiens (human)Potency19.744040
promazineHomo sapiens (human)Potency15.585420
promethazineHomo sapiens (human)Potency14.689220
propafenoneHomo sapiens (human)Potency21.301620
raloxifeneHomo sapiens (human)Potency21.363930
pf 5901Homo sapiens (human)Potency26.121610
ritanserinHomo sapiens (human)Potency15.080420
sanguinarineHomo sapiens (human)Potency3.288510
terfenadineHomo sapiens (human)Potency16.907140
thioridazineHomo sapiens (human)Potency14.892130
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoateHomo sapiens (human)Potency23.280910
triamtereneHomo sapiens (human)Potency16.481610
trifluoperazineHomo sapiens (human)Potency15.884130
trifluperidolHomo sapiens (human)Potency13.890520
triflupromazineHomo sapiens (human)Potency22.307220
ics 205-930Homo sapiens (human)Potency8.168720
tyrphostin a9Homo sapiens (human)Potency3.234020
corticosteroneHomo sapiens (human)Potency16.481610
4-[(1S)-1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diolHomo sapiens (human)Potency26.121610
tetrabenazineHomo sapiens (human)Potency23.280910
bromodeoxyuridineHomo sapiens (human)Potency13.091810
cytarabineHomo sapiens (human)Potency0.769930
rotenoneHomo sapiens (human)Potency0.052520
pyrazolanthroneHomo sapiens (human)Potency20.749110
yohimbineHomo sapiens (human)Potency14.689210
azacitidineHomo sapiens (human)Potency5.180730
emetineHomo sapiens (human)Potency3.530620
amiloride hydrochloride, anhydrousHomo sapiens (human)Potency20.504510
pimozideHomo sapiens (human)Potency20.591440
propionylpromazineHomo sapiens (human)Potency19.881220
camptothecinHomo sapiens (human)Potency0.075220
ancitabineHomo sapiens (human)Potency1.558620
metergolineHomo sapiens (human)Potency24.701320
bromocriptineHomo sapiens (human)Potency18.492710
zidovudineHomo sapiens (human)Potency28.963310
butaclamolHomo sapiens (human)Potency14.073520
methyldopaHomo sapiens (human)Potency23.001440
idarubicinHomo sapiens (human)Potency6.202440
paroxetineHomo sapiens (human)Potency20.323940
mitoxantrone hydrochlorideHomo sapiens (human)Potency2.350620
idazoxanHomo sapiens (human)Potency10.594340
mifepristoneHomo sapiens (human)Potency17.474520
salmeterol xinafoateHomo sapiens (human)Potency14.689220
mibefradilHomo sapiens (human)Potency15.119140
eliprodilHomo sapiens (human)Potency14.689210
aptiganelHomo sapiens (human)Potency19.881220
ziprasidone hydrochlorideHomo sapiens (human)Potency23.280910
verapamil hydrochlorideHomo sapiens (human)Potency4.590410
mevastatinHomo sapiens (human)Potency12.875020
rutecarpineHomo sapiens (human)Potency18.492710
lercanidipineHomo sapiens (human)Potency21.363930
2-methoxyestradiolHomo sapiens (human)Potency5.211910
sertralineHomo sapiens (human)Potency24.214440
masoprocolHomo sapiens (human)Potency18.492710
3-octadecanamido-2-ethoxypropylphosphocholineHomo sapiens (human)Potency18.492710
amperozideHomo sapiens (human)Potency23.280910
sk&f 95282Homo sapiens (human)Potency19.881220
zpckHomo sapiens (human)Potency14.956640
1-amino-1,3-dicarboxycyclopentaneHomo sapiens (human)Potency0.261210
cp-55,940Homo sapiens (human)Potency19.694930
cv 3988Homo sapiens (human)Potency24.701320
gr 127935Homo sapiens (human)Potency11.164840
1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazineHomo sapiens (human)Potency18.492710
tetradecanoylphorbol acetateHomo sapiens (human)Potency23.991140
imatinib mesylateHomo sapiens (human)Potency16.287310
l 687384Homo sapiens (human)Potency23.280910
indatralineHomo sapiens (human)Potency18.738940
lestaurtinibHomo sapiens (human)Potency8.171820
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamideHomo sapiens (human)Potency23.280910
sk&f 83959Homo sapiens (human)Potency16.591020
l 741626Homo sapiens (human)Potency8.508620
canertinibHomo sapiens (human)Potency13.908920
n-n-propylnorapomorphineHomo sapiens (human)Potency26.121610
fiduxosinHomo sapiens (human)Potency22.553340
sk&f 75670Homo sapiens (human)Potency19.881220
erlotinibHomo sapiens (human)Potency20.504510
nsc 95397Homo sapiens (human)Potency2.499520
pifithrin muHomo sapiens (human)Potency22.015020
nu 6027Homo sapiens (human)Potency17.547340
nexavarHomo sapiens (human)Potency11.339520
5-hydroxytryptophanHomo sapiens (human)Potency20.886820
tosylphenylalanyl chloromethyl ketoneHomo sapiens (human)Potency19.751140
pancuroniumHomo sapiens (human)Potency0.207510
L-isoprenalineHomo sapiens (human)Potency23.280910
resveratrolHomo sapiens (human)Potency11.091220
thapsigarginHomo sapiens (human)Potency6.539940
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diolHomo sapiens (human)Potency16.481610
6-bromoindirubin-3'-oximeHomo sapiens (human)Potency11.368360
isoliquiritigeninHomo sapiens (human)Potency26.121610
gw9662Homo sapiens (human)Potency14.689210
3,3',4,5'-tetrahydroxystilbeneHomo sapiens (human)Potency23.280920
3,4-methylenedioxy-beta-nitrostyreneHomo sapiens (human)Potency2.645630
carbidopa, (r)-isomerHomo sapiens (human)Potency16.481610
(e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamideHomo sapiens (human)Potency23.280910
sch-202676Homo sapiens (human)Potency26.121610
phenylthiazolylthioureaHomo sapiens (human)Potency14.359530
10,11-dihydroxy-n-allylnoraporphineHomo sapiens (human)Potency16.741820
[3-amino-6-(4-methoxyphenyl)-2-thieno[2,3-b]pyridinyl]-(3,4-dimethoxyphenyl)methanoneHomo sapiens (human)Potency13.178620
fluoxetineHomo sapiens (human)Potency24.701320
SMER 28Homo sapiens (human)Potency23.280910
ac 55649Homo sapiens (human)Potency23.280910
amn082Homo sapiens (human)Potency15.792220
tamoxifen citrateHomo sapiens (human)Potency18.274610
tamoxifenHomo sapiens (human)Potency18.498240
statticHomo sapiens (human)Potency1.553530
cgp 74514aHomo sapiens (human)Potency16.006740
1,4-bis[2-(4-hydroxyphenyl)ethylamino]anthracene-9,10-dioneHomo sapiens (human)Potency4.645120
nemadipine-aHomo sapiens (human)Potency20.461240
bp 897Homo sapiens (human)Potency21.301620
safingolHomo sapiens (human)Potency20.504510
dasatinibHomo sapiens (human)Potency4.331030
zd 6474Homo sapiens (human)Potency6.625120
sb 242084Homo sapiens (human)Potency18.186320
(4-chlorophenyl)-[4-(8-nitro-5-quinolinyl)-1-piperazinyl]methanoneHomo sapiens (human)Potency20.749110
bw 723c86Homo sapiens (human)Potency13.091820
le 300Homo sapiens (human)Potency26.121610
cyclosporineHomo sapiens (human)Potency7.522220
myricetinHomo sapiens (human)Potency19.881220
caffeic acid phenethyl esterHomo sapiens (human)Potency4.404330
flupenthixolHomo sapiens (human)Potency19.097530
n-oleoyldopamineHomo sapiens (human)Potency6.080440
isotretinoinHomo sapiens (human)Potency4.645110
fenretinideHomo sapiens (human)Potency17.836840
as 605240Homo sapiens (human)Potency19.097530
su 9516Homo sapiens (human)Potency17.301040
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acidHomo sapiens (human)Potency0.521210
olvanilHomo sapiens (human)Potency7.370020
(3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanoneHomo sapiens (human)Potency16.554530
su 6656Homo sapiens (human)Potency7.116240
casein kinase iiHomo sapiens (human)Potency13.985420
tyrphostin ag 555Homo sapiens (human)Potency17.487220
ag-490Homo sapiens (human)Potency18.492710
semaxinibHomo sapiens (human)Potency2.102820
bay 11-7082Homo sapiens (human)Potency0.521210
guanabenzHomo sapiens (human)Potency2.074910
n,n,n-trimethyl-1-(4-stilbenoxy)-2-propylammonium iodideHomo sapiens (human)Potency8.299220
gw-5074Homo sapiens (human)Potency4.645110
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-oneHomo sapiens (human)Potency20.405420
7-chloro-4-hydroxy-2-phenyl-1,8-naphthyridineHomo sapiens (human)Potency1.039910
su 4312Homo sapiens (human)Potency7.348820
tanespimycinHomo sapiens (human)Potency2.417230
a 77636Homo sapiens (human)Potency19.418430
b 43Homo sapiens (human)Potency13.091810
(8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triolHomo sapiens (human)Potency16.837140
(8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triolHomo sapiens (human)Potency18.985040
dilazep(2+)Homo sapiens (human)Potency24.701320
erythro-dihydrosphingosineHomo sapiens (human)Potency20.886820
gw2974Homo sapiens (human)Potency26.121610
l 162313Homo sapiens (human)Potency17.487220
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(-)-isomerHomo sapiens (human)Potency20.405420
sb 218795Homo sapiens (human)Potency18.492710
ro 25-6981Homo sapiens (human)Potency26.121610
pd 184352Homo sapiens (human)Potency14.831820
17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5'-guanidinyl-3,14-dihydroxyindolo(2',3'-6,7)morphinanHomo sapiens (human)Potency23.280920
a 134974Homo sapiens (human)Potency11.668110
1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1h-indoleHomo sapiens (human)Potency26.121610
sb 525334Homo sapiens (human)Potency5.211910
methylhistaprodifenHomo sapiens (human)Potency21.798040
(5R)-9-bromo-5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diolHomo sapiens (human)Potency24.701320
N(2)-([biphenyl]-4-ylsulfonyl)-N-hydroxy-N(2)-isopropoxy-D-valinamideHomo sapiens (human)Potency15.984820
cgp 57380Homo sapiens (human)Potency5.211910
b 015Homo sapiens (human)Potency18.460340
calcimycinHomo sapiens (human)Potency5.274640
2-[(7-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-N-(3-methoxypropyl)acetamideHomo sapiens (human)Potency8.810020
4-chloro-N-[3-(3-methyl-1-piperidinyl)propyl]-2-thieno[3,2-c]quinolinecarboxamideHomo sapiens (human)Potency15.702850
5-chloro-2-[(4-methylphenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamideHomo sapiens (human)Potency9.499460
5-chloro-2-[(3-methylphenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamideHomo sapiens (human)Potency15.457460
N-[(2-chlorophenyl)methyl]-2-(4-ethyl-1-oxo-2-pyrrolo[1,2-d][1,2,4]triazinyl)acetamideHomo sapiens (human)Potency2.950420
N-(2-ethyl-6-methylphenyl)-2-(4-methyl-1-oxo-2-pyrrolo[1,2-d][1,2,4]triazinyl)acetamideHomo sapiens (human)Potency2.994620
[4-(2,3-dimethylphenyl)-1-piperazinyl]-[5-[(4-methylphenyl)sulfonylmethyl]-2-furanyl]methanoneHomo sapiens (human)Potency26.121610
bix 01294Homo sapiens (human)Potency9.476840
(E,E)-1-bromo-2,5-bis-(4-hydroxystyryl)benzeneHomo sapiens (human)Potency18.492710
norclozapineHomo sapiens (human)Potency15.792220
ag-879Homo sapiens (human)Potency24.701320