Page last updated: 2024-08-07 11:25:08
DNA ligase A
[no definition available]
Synonyms
LigA;
EC 6.5.1.2;
Polydeoxyribonucleotide synthase [NAD(+)]
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| chloroquine | Mycobacterium tuberculosis H37Rv | IC50 | 823.0000 | 2 | 4 |
NAD+-dependent DNA ligase (Rv3014c) from Mycobacterium tuberculosis: novel structure-function relationship and identification of a specific inhibitor.Proteins, , Oct-01, Volume: 69, Issue:1, 2007
NAD+-dependent DNA Ligase (Rv3014c) from Mycobacterium tuberculosis. Crystal structure of the adenylation domain and identification of novel inhibitors.The Journal of biological chemistry, , Aug-26, Volume: 280, Issue:34, 2005