Proteins > pyruvate kinase PKM isoform a
Page last updated: 2024-08-07 12:36:55

pyruvate kinase PKM isoform a

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (417)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoic acidHomo sapiens (human)Potency39.810720
acemetacinHomo sapiens (human)Potency39.810720
amlexanoxHomo sapiens (human)Potency14.125420
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolHomo sapiens (human)Potency31.622820
benzothiazideHomo sapiens (human)Potency39.810720
ebselenHomo sapiens (human)Potency5.118940
ethoxzolamideHomo sapiens (human)Potency25.118920
1-(2-naphthalenyl)-2-propen-1-oneHomo sapiens (human)Potency10.000020
vitamin k 3Homo sapiens (human)Potency15.848920
omeprazoleHomo sapiens (human)Potency7.079520
thiramHomo sapiens (human)Potency14.125420
p-aminoazobenzeneHomo sapiens (human)Potency39.810720
methylene blueHomo sapiens (human)Potency39.810720
n-oxydiethylene-2-benzothiazole sulfenamideHomo sapiens (human)Potency14.125420
1,2-naphthoquinoneHomo sapiens (human)Potency12.589320
4-(benzoylamino)-2-hydroxybenzoic acidHomo sapiens (human)Potency39.810720
eriodictyolHomo sapiens (human)Potency11.220220
monoacetyldapsoneHomo sapiens (human)Potency8.912520
indole-3-acetic acid ethyl esterHomo sapiens (human)Potency25.118920
monolinuronHomo sapiens (human)Potency1.584920
2-(alpha-thenoylamino)-2-nitro-5-thiazoleHomo sapiens (human)Potency15.848920
1,6-bismaleimidohexaneHomo sapiens (human)Potency8.835530
diacereinHomo sapiens (human)Potency28.183820
n-(cyclohexylthio)phthalimideHomo sapiens (human)Potency22.387220
zidovudineHomo sapiens (human)Potency39.810720
nitazoxanideHomo sapiens (human)Potency14.125420
whr-1142aHomo sapiens (human)Potency7.079520
epigallocatechin gallateHomo sapiens (human)Potency3.981120
2-(2'-pyridyl)benzimidazoleHomo sapiens (human)Potency15.848920
2-amino-4-tert-butylphenolHomo sapiens (human)Potency14.125420
9-methoxyellipticineHomo sapiens (human)Potency35.481320
methyl fluorone blackHomo sapiens (human)Potency10.000020
3,5-di-tert-butyl-1,2-benzoquinoneHomo sapiens (human)Potency1.412520
6-aminoindazoleHomo sapiens (human)Potency25.118920
2-(4-hydroxyphenyl)-5,6,7,8-tetrahydroxy-4H-1-benzopyran-4-oneHomo sapiens (human)Potency39.810720
2-(4-phenylphenoxy)propanoic acidHomo sapiens (human)Potency7.943320
2-phenyl-1,2-benzisothiazol-3-(2h)-oneHomo sapiens (human)Potency39.810720
4-butyl-4-(hydroxymethyl)-1,2-diphenylpyrazolidine-3,5-dioneHomo sapiens (human)Potency7.079520
1-benzylimidazole-4,5-dicarboxylic acidHomo sapiens (human)Potency35.481320
4-methylthiazole-5-carboxylic acidHomo sapiens (human)Potency35.481320
4-(2-methyl-5-phenyl-1-pyrrolyl)benzoic acidHomo sapiens (human)Potency19.952620
gossypol acetic acidHomo sapiens (human)Potency31.622820
3-nitrotyrosineHomo sapiens (human)Potency31.622820
2-acetamido-2-(hydroxymethyl)propanedioic acid diethyl esterHomo sapiens (human)Potency7.943320
2-hydroxyestradiolHomo sapiens (human)Potency0.354820
4,7-dimethoxy-2,3-dimethyl-1H-indoleHomo sapiens (human)Potency19.952620
(RS)-coclaurineHomo sapiens (human)Potency25.118920
2-methyl-3-(phenylmethylthio)-1H-indoleHomo sapiens (human)Potency35.481320
nsc 401077Homo sapiens (human)Potency25.118920
4,5,7-trihydroxy-9,10-dioxo-2-anthracenecarboxylic acidHomo sapiens (human)Potency17.782820
1-[1-(benzenesulfonyl)-3-pyrrolyl]ethanoneHomo sapiens (human)Potency22.387220
2-[[[2-methyl-1-(phenylmethyl)-5-benzimidazolyl]amino]methyl]phenolHomo sapiens (human)Potency5.011920
4-Morpholinyl(4-pentylcyclohexyl)methanoneHomo sapiens (human)Potency0.281820
5-(4-nitrophenyl)-4-phenyl-2-thiazolamineHomo sapiens (human)Potency19.952620
2-imino-N,8-dimethyl-5-oxo-1-propan-2-yl-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamideHomo sapiens (human)Potency0.006320
N-(3-hydroxyphenyl)-2-[[4-methyl-5-[4-(4-morpholinylsulfonyl)phenyl]-1,2,4-triazol-3-yl]thio]acetamideHomo sapiens (human)Potency28.183820
1-(2,5-dimethoxyphenyl)-2-[[5-(2-furanyl)-4-propyl-1,2,4-triazol-3-yl]thio]ethanoneHomo sapiens (human)Potency3.981120
3-[(2-fluorophenyl)methyl]-7-(1-imidazolyl)triazolo[4,5-d]pyrimidineHomo sapiens (human)Potency1.122020
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[1-(3,4-dimethoxyphenyl)-5-tetrazolyl]thio]acetamideHomo sapiens (human)Potency0.316220
2-(2-ethyl-6-methyl-3-oxo-1,4-benzoxazin-4-yl)-N-[(5-methyl-2-furanyl)methyl]-N-(3-pyridinylmethyl)acetamideHomo sapiens (human)Potency1.000020
N,N-dimethyl-6-phenyl-3-pyridazinamineHomo sapiens (human)Potency25.118920
1-(4-chlorophenyl)sulfonyl-N-[3-methoxy-4-(1-tetrazolyl)phenyl]-4-piperidinecarboxamideHomo sapiens (human)Potency0.010020
N-(2-hydroxyethyl)-5-methyl-N-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-2,1,3-benzothiadiazole-4-sulfonamideHomo sapiens (human)Potency39.810720
3-[1-azepanyl-[1-(phenylmethyl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-oneHomo sapiens (human)Potency14.125420
3-[[2-[[5-[(4-cyanophenoxy)methyl]-4-phenyl-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]benzoic acid methyl esterHomo sapiens (human)Potency0.794320
5-ethyl-3-[(2-fluorophenyl)methyl]-N-[2-(2-pyridinyl)ethyl]-7-triazolo[4,5-d]pyrimidinamineHomo sapiens (human)Potency25.118920
N-[1-(2-methoxyphenyl)-5-benzimidazolyl]benzenesulfonamideHomo sapiens (human)Potency10.000020
2,5-diethoxy-N-[2-(2-methylphenyl)ethyl]-4-(1-tetrazolyl)benzenesulfonamideHomo sapiens (human)Potency12.589320
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(4-methoxyphenyl)sulfonylpiperazineHomo sapiens (human)Potency0.234040
2-acetyl-6-amino-8-(2-phenylethyl)-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrileHomo sapiens (human)Potency39.810720
1-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-piperidinyl]-5-fluorobenzotriazoleHomo sapiens (human)Potency8.912520
4-[(3-fluorophenyl)methyl-(3-pyridinylmethyl)amino]-4-oxobutanoic acidHomo sapiens (human)Potency3.548120
N-(2-furanylmethyl)-1-(phenylmethyl)-4-pyrazolo[3,4-d]pyrimidinamineHomo sapiens (human)Potency14.125420
N-cyclopropyl-4-(2,3-dihydroindol-1-ylsulfonyl)benzenesulfonamideHomo sapiens (human)Potency15.848920
N-[(1,3-dimethyl-4-pyrazolyl)methyl]-5-(2-furanyl)-N-methyl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency39.810720
6-(3,4-dimethoxyphenyl)-4-methoxy-1,3-dimethyl-8-cyclohepta[c]furanoneHomo sapiens (human)Potency35.481320
LSM-34679Homo sapiens (human)Potency2.818420
6-[(2-fluorophenyl)methyl]-2,4-dimethyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency0.163260
1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-furanylmethyl)-3-phenylureaHomo sapiens (human)Potency7.943320
2-[[6-(3,4-dimethoxyphenyl)-3-pyridazinyl]thio]-1-(4-morpholinyl)ethanoneHomo sapiens (human)Potency0.794320
4-amino-2-[[2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]thio]-5-pyrimidinecarboxylic acid ethyl esterHomo sapiens (human)Potency39.810720
N-[(2-methoxyphenyl)methyl]-3-(phenylmethyl)-7-triazolo[4,5-d]pyrimidinamineHomo sapiens (human)Potency19.952620
4-[[4-(1,3-benzothiazol-2-yl)-1-piperazinyl]-[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]-2-methoxyphenolHomo sapiens (human)Potency19.952620
3-[1-(2-furanylmethyl)-5-phenyl-2-pyrrolyl]propanoic acidHomo sapiens (human)Potency35.481320
4-(4-methoxyphenyl)sulfonyl-N-(phenylmethyl)-1-piperazinecarboxamideHomo sapiens (human)Potency7.079520
3,7-dimethyl-1-(phenylmethyl)-8-[(phenylmethyl)amino]purine-2,6-dioneHomo sapiens (human)Potency22.387220
8-(2-furanyl)-6-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-3,3-dimethyl-1,4-dihydrothiopyrano[3,4-c]pyridine-5-carbonitrileHomo sapiens (human)Potency35.481320
2',2'-dimethyl-3-spiro[5,6,7,8a-tetrahydrothiazolo[3,2-a]pyridine-8,4'-thiane]oneHomo sapiens (human)Potency39.810720
N-(3-methoxyphenyl)-2-(2-pyridinylthio)acetamideHomo sapiens (human)Potency39.810720
2,6-dimethyl-4-[1-(2-naphthalenylsulfonyl)-4-piperidinyl]morpholineHomo sapiens (human)Potency15.848920
2-[[2-methyl-5-(3-methyl-4-oxo-1-phthalazinyl)phenyl]sulfonylamino]acetic acid ethyl esterHomo sapiens (human)Potency39.810720
2-[[(1-propan-2-yl-2-benzimidazolyl)amino]methyl]-6-prop-2-enylphenolHomo sapiens (human)Potency31.622820
3-(4-chlorophenyl)-6-(thiophen-2-ylmethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleHomo sapiens (human)Potency2.238720
(4-chloro-5-hydroxy-3-benzofuranyl)-phenylmethanoneHomo sapiens (human)Potency35.481320
3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dioneHomo sapiens (human)Potency3.981120
1-[(4-fluorophenyl)methyl]-3-(2-furanylmethyl)-4-imino-6,6-dimethyl-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-2-oneHomo sapiens (human)Potency15.848920
3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-pyridinyl)propanamideHomo sapiens (human)Potency8.912520
N-(5-methyl-7-phenyl-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-thiophenecarboxamideHomo sapiens (human)Potency35.481320
N-(2-furanylmethyl)-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]-2-thiophenecarboxamideHomo sapiens (human)Potency12.589320
2-amino-6-[3-(1-imidazolyl)propyl]-4-(2-methoxyphenyl)-7-methyl-5-oxo-4H-pyrano[3,2-c]pyridine-3-carbonitrileHomo sapiens (human)Potency19.952620
3-(1-benzimidazolylmethyl)-6-[(4-methoxyphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleHomo sapiens (human)Potency25.118920
4-[(4-ethyl-1-piperazinyl)methyl]-5,7-dimethyl-1-benzopyran-2-oneHomo sapiens (human)Potency22.387220
5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-oneHomo sapiens (human)Potency39.810720
4-methyl-N-[4-(4-morpholinyl)phenyl]benzamideHomo sapiens (human)Potency39.810720
4-(4-propan-2-yl-1-piperazinyl)phenolHomo sapiens (human)Potency7.943320
2-(4-ethylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamideHomo sapiens (human)Potency8.912520
6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylic acid ethyl esterHomo sapiens (human)Potency7.079520
N-[(4-pyrimidinylthio)methyl]benzamideHomo sapiens (human)Potency22.387220
N-[2-(1H-benzimidazol-2-yl)ethyl]-4-chloro-3-nitrobenzamideHomo sapiens (human)Potency14.125420
4-(benzylsulfanyl)thieno[2,3-d]pyrimidineHomo sapiens (human)Potency35.481320
2-methyl-5-(5-methyl-2-furanyl)-3-(1-pyrrolyl)-4-thieno[2,3-d]pyrimidinoneHomo sapiens (human)Potency22.387220
2-(1,3-benzodioxol-5-ylmethyl)isoindole-1,3-dioneHomo sapiens (human)Potency31.622820
2-methoxy-6-[[(1-methyl-2-benzimidazolyl)amino]methyl]phenolHomo sapiens (human)Potency22.387220
4-chloro-N-(3,4,5-trimethoxyphenyl)-5-dithiazolimineHomo sapiens (human)Potency25.118920
7-methoxy-3,5-dimethyl-2-thiazolo[4,5-d]pyrimidinethioneHomo sapiens (human)Potency1.584920
N-[4-(4-ethylphenyl)-2-thiazolyl]carbamic acid phenyl esterHomo sapiens (human)Potency39.810720
N-(2-phenyl-3-imidazo[1,2-a]pyridinyl)carbamic acid methyl esterHomo sapiens (human)Potency39.810720
acetic acid [2-(2-methylphenyl)-4-oxo-3,1-benzoxazin-7-yl] esterHomo sapiens (human)Potency0.794320
4-pyridin-4-yl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-quinoline-3-carbonitrileHomo sapiens (human)Potency22.387220
nsc185058Homo sapiens (human)Potency15.848920
4-[bis(phenylmethyl)amino]-2-(dimethylamino)-3-pyridinecarbonitrileHomo sapiens (human)Potency0.707920
(3-hydroxy-5,6,7,8-tetrahydro-4H-cyclohepta[d]imidazol-2-yl)-phenylmethanoneHomo sapiens (human)Potency5.623420
4-chloro-N-(4-hydrazinyl-6-methyl-2-pyrimidinyl)benzenesulfonamideHomo sapiens (human)Potency35.481320
2-hydroxy-5-[[(5-methyl-2-furanyl)-oxomethyl]amino]benzoic acidHomo sapiens (human)Potency35.481320
[5-(4-nitrophenyl)-2-furanyl]-(1-piperidinyl)methanoneHomo sapiens (human)Potency39.810720
3-chloro-1-(2-chlorophenyl)-4-(4-morpholinyl)pyrrole-2,5-dioneHomo sapiens (human)Potency39.810720
4-[[(4-acetyloxy-3-methoxyphenyl)-oxomethyl]amino]benzoic acidHomo sapiens (human)Potency14.125420
5-(4-chlorophenyl)-2-furanpropionic acidHomo sapiens (human)Potency22.387220
2-[[4-(1-pyrrolidinylsulfonyl)phenyl]hydrazinylidene]propanedinitrileHomo sapiens (human)Potency22.387220
N-(1,3-benzodioxol-5-yl)-5-methyl-2-furancarboxamideHomo sapiens (human)Potency17.782820
2-(1H-benzimidazol-2-ylmethyl)benzene-1,4-diolHomo sapiens (human)Potency39.810720
lupitidineHomo sapiens (human)Potency28.183820
N-(2-furanylmethyl)-1,3-dioxo-2-propyl-5-isoindolecarboxamideHomo sapiens (human)Potency15.848920
3-[1-(4-acetylphenyl)-5-thiophen-2-yl-2-pyrrolyl]propanoic acidHomo sapiens (human)Potency15.848920
1-[(4-methylphenyl)methyl]-4-(1-pyrrolidinyl)pyrazolo[3,4-d]pyrimidineHomo sapiens (human)Potency12.589320
N-(5-acetyl-4-methyl-2-thiazolyl)-5-bromo-2-furancarboxamideHomo sapiens (human)Potency22.387220
3,6-dichloro-N-(3-pyridinylmethyl)-1-benzothiophene-2-carboxamideHomo sapiens (human)Potency22.387220
2-[[3-(5-methyl-2-furanyl)-1-oxopropyl]amino]benzene-1,4-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency39.810720
curcuminHomo sapiens (human)Potency28.183820
3-[[(3-acetylanilino)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl esterHomo sapiens (human)Potency19.952620
1-cyclopentyl-3-(2-phenoxyphenyl)thioureaHomo sapiens (human)Potency3.981120
4-[2-(3-methoxyanilino)-4-thiazolyl]phenolHomo sapiens (human)Potency0.891320
3-[(2-ethyl-1-oxobutyl)amino]-N-(2-furanylmethyl)benzamideHomo sapiens (human)Potency17.782820
N-(2-pyridinyl)-2-[[5-(3-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]acetamideHomo sapiens (human)Potency35.481320
9-hydroxy-4-[1-oxo-2-[4-(phenylmethyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-[1]benzopyrano[3,4-b]pyridin-5-oneHomo sapiens (human)Potency7.079520
N-(5-bromo-8-quinolinyl)-5-[(4-chloro-1-pyrazolyl)methyl]-2-furancarboxamideHomo sapiens (human)Potency5.011920
3-chloro-4,5-dimethoxy-N-(1-naphthalenylmethyl)benzamideHomo sapiens (human)Potency17.782820
4-[[[[oxo-(4-phenylphenyl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acidHomo sapiens (human)Potency35.481320
1,4-bis(thiophen-2-ylsulfonyl)piperazineHomo sapiens (human)Potency0.398120
2-[[4-(4-methylphenyl)sulfonyl-1-piperazinyl]methyl]-4-propan-2-ylphenolHomo sapiens (human)Potency19.952620
N-(3,5-dimethylphenyl)-4-(3-methoxyphenyl)-1-piperazinecarbothioamideHomo sapiens (human)Potency0.707920
N-[(2-chlorophenyl)methyl]-1-(4-methylphenyl)sulfonyl-4-piperidinecarboxamideHomo sapiens (human)Potency12.589320
N-[4-(1-pyrrolidinylsulfonyl)phenyl]-2-thiophen-2-ylacetamideHomo sapiens (human)Potency22.387220
N-[4-(1-piperidinylsulfonyl)phenyl]-2-thiophenesulfonamideHomo sapiens (human)Potency17.782820
N-(5-chloro-2-hydroxyphenyl)-1,3-dimethyl-2-oxo-5-benzimidazolesulfonamideHomo sapiens (human)Potency12.589320
1-methyl-2-oxo-N-(2-pyridinyl)-6-benzo[cd]indolesulfonamideHomo sapiens (human)Potency3.981120
5-bromo-2-methoxy-N-(3-methyl-2-pyridinyl)benzenesulfonamideHomo sapiens (human)Potency6.309620
N-[4-[[[[oxo(thiophen-2-yl)methyl]amino]-sulfanylidenemethyl]amino]phenyl]-2-furancarboxamideHomo sapiens (human)Potency25.118920
1,4-bis[(4-methoxy-2-methylphenyl)sulfonyl]-1,4-diazepaneHomo sapiens (human)Potency8.912520
4-[4-(benzenesulfonyl)-1-piperazinyl]-2-methylquinolineHomo sapiens (human)Potency25.118920
1-[(7,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-furanylmethyl)-3-(2-methoxyphenyl)thioureaHomo sapiens (human)Potency31.622820
(E)-4-Phenyl-2-(3-(thiophen-2-yl)acrylamido)thiophene-3-carboxylic acidHomo sapiens (human)Potency39.810720
2-(3-ethylphenoxy)-N-[4-(2-pyridinylsulfamoyl)phenyl]acetamideHomo sapiens (human)Potency22.387220
7-(diethylaminomethyl)-1-(4-methoxyphenyl)-2-methyl-3-nitro-6-indololHomo sapiens (human)Potency39.810720
4-(3-bromophenyl)-2-(4-bromophenyl)-7-methylpyrazolo[3,4-d]pyridazineHomo sapiens (human)Potency8.912520
N-[[1-(benzenesulfonyl)-4-piperidinyl]methyl]benzenesulfonamideHomo sapiens (human)Potency2.818420
N-[4-[(N-methylanilino)-oxomethyl]phenyl]-2-furancarboxamideHomo sapiens (human)Potency28.183820
N-(2-furanylmethyl)-5-methyl-4-phenyl-3-thiophenecarboxamideHomo sapiens (human)Potency39.810720
1,3-diethyl-6-methyl-N-(2-methylphenyl)-2-oxo-5-benzimidazolesulfonamideHomo sapiens (human)Potency12.589320
N2,N2-dimethyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamineHomo sapiens (human)Potency12.589320
2-[2-chloro-4-(2,3-dihydroindol-1-ylsulfonyl)phenoxy]-N-(2-pyridinylmethyl)acetamideHomo sapiens (human)Potency15.848920
2-[[[(4-methoxyphenyl)-oxomethyl]amino]methyl]-5-phenyl-3-furancarboxylic acidHomo sapiens (human)Potency28.183820
1-(4-bromo-3-ethoxyphenyl)sulfonyl-3,5-dimethylpyrazoleHomo sapiens (human)Potency31.622820
2-[[5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl]thio]-N-(2-pyridinyl)acetamideHomo sapiens (human)Potency10.000020
N-(4-methyl-2-thiazolyl)-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]acetamideHomo sapiens (human)Potency14.125420
4-(5-methyl-2-furanyl)-2-[[2-(4-morpholinyl)-1-oxoethyl]amino]-3-thiophenecarboxylic acid ethyl esterHomo sapiens (human)Potency19.952620
4-[[4-(dimethylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]oxy]benzoic acid methyl esterHomo sapiens (human)Potency1.584920
9-(3-bromo-4-hydroxyphenyl)-10-phenyl-3,4,5,6,7,9-hexahydro-2H-acridine-1,8-dioneHomo sapiens (human)Potency39.810720
darunavir ethanolateHomo sapiens (human)Potency35.481320
2-[2,5-dimethyl-3-[(2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1-pyrrolyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl esterHomo sapiens (human)Potency10.000020
N-[4-[[2-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolyl]oxy]phenyl]-2,2-dimethylpropanamideHomo sapiens (human)Potency10.000020
2-[(5-amino-7-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-3-yl)thio]-N-(3-methoxyphenyl)acetamideHomo sapiens (human)Potency1.778320
1-(4-methylphenyl)sulfonyl-4-(2-naphthalenylsulfonyl)-1,4-diazepaneHomo sapiens (human)Potency0.707920
9-methyl-5,6,7,8-tetrahydrotetrazolo[5,1-b]quinazolineHomo sapiens (human)Potency39.810720
4-methyl-N-[(2-methyl-4-quinolinyl)methyl]-3-nitrobenzamideHomo sapiens (human)Potency35.481320
3-methyl-N-[oxo-[(2,4,6-trimethyl-3-pyridinyl)amino]methyl]benzamideHomo sapiens (human)Potency39.810720
6-fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-oneHomo sapiens (human)Potency35.481320
4-methoxy-N-(8-methyl-[1,3]dioxolo[4,5-g]quinazolin-6-yl)benzamideHomo sapiens (human)Potency39.810720
N2,N2-dimethyl-6-[[[1-(1-naphthalenyl)-5-tetrazolyl]thio]methyl]-1,3,5-triazine-2,4-diamineHomo sapiens (human)Potency3.548120
1-[[1-oxo-3-(4-propan-2-yloxyphenyl)propyl]amino]-3-(phenylmethyl)thioureaHomo sapiens (human)Potency0.005620
5-[(6-hydroxy-4-oxo-1-benzopyran-3-yl)methylidene]-1,3-diazinane-2,4,6-trioneHomo sapiens (human)Potency31.622820
3,4,5-trimethoxy-N-(3-methyl-1,3-benzothiazol-2-ylidene)benzamideHomo sapiens (human)Potency25.118920
1-(1,3-benzodioxol-5-ylmethylthio)-[1,2,4]triazolo[4,3-a]quinolineHomo sapiens (human)Potency14.125420
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[(4-fluorophenyl)thio]ethanoneHomo sapiens (human)Potency3.162320
2-(2-bromophenyl)-5-[(7-nitro-4-quinazolinyl)oxymethyl]-1,3,4-oxadiazoleHomo sapiens (human)Potency31.622820
2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] esterHomo sapiens (human)Potency15.848920
2,6-dichloro-N-[2-(methylthio)-1,3-benzothiazol-6-yl]benzenesulfonamideHomo sapiens (human)Potency22.387220
N-(3-acetyl-2-methyl-5-benzofuranyl)-N-(8-quinolinylsulfonyl)acetamideHomo sapiens (human)Potency31.622820
5-[[2-[(3-methylphenyl)methyl]-1-oxo-3,4-dihydroisoquinolin-5-yl]oxymethyl]-2-furancarboxylic acid methyl esterHomo sapiens (human)Potency22.387220
2-[[5-(5-chloro-2-thiophenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(3,4-dihydro-2H-quinolin-1-yl)ethanoneHomo sapiens (human)Potency19.952620
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[(4-methyl-2-thiazolyl)thio]ethanoneHomo sapiens (human)Potency31.622820
1-cyclohexyl-3-(6-ethoxy-1,3-benzothiazol-2-yl)ureaHomo sapiens (human)Potency39.810720
2-[[1-oxo-2-(1H-1,2,4-triazol-5-ylthio)ethyl]amino]-4-thiophen-2-yl-3-thiophenecarboxylic acid ethyl esterHomo sapiens (human)Potency28.183820
4-(5-methyl-2-furanyl)-2-[[1-oxo-2-(1H-1,2,4-triazol-5-ylthio)ethyl]amino]-3-thiophenecarboxylic acid ethyl esterHomo sapiens (human)Potency8.912520
2-(methanesulfonamido)-N-[2-(phenylmethylthio)ethyl]benzamideHomo sapiens (human)Potency39.810720
2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-oneHomo sapiens (human)Potency0.354820
2-[(4-fluoro-2-methylphenyl)sulfonylamino]-N-(3-pyridinylmethyl)benzamideHomo sapiens (human)Potency25.118920
2-methoxy-4-(methylthio)benzoic acid [2-(cyclopropylamino)-2-oxoethyl] esterHomo sapiens (human)Potency39.810720
2,8-dimercapto-6-hydroxypurineHomo sapiens (human)Potency28.183820
N-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)-2-furancarboxamideHomo sapiens (human)Potency39.810720
2-[[[[(4-fluorophenyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]-4-(5-methyl-2-furanyl)-3-thiophenecarboxylic acid ethyl esterHomo sapiens (human)Potency7.943320
1-(2,6-diethylphenyl)-3-[2-(3,4-dihydroxyphenyl)ethyl]thioureaHomo sapiens (human)Potency22.387220
4-chloro-3-(1-pyrrolidinylsulfonyl)benzoic acid [2-(butylamino)-2-oxoethyl] esterHomo sapiens (human)Potency14.125420
6-amino-1-(2-methoxyethyl)-N-(4-methylphenyl)sulfonyl-2,4-dioxo-5-pyrimidinecarboxamideHomo sapiens (human)Potency25.118920
7-[[[1-(2-methylphenyl)-5-tetrazolyl]thio]methyl]-5-thiazolo[3,2-a]pyrimidinoneHomo sapiens (human)Potency0.794320
N-[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-methylacetamideHomo sapiens (human)Potency22.387220
2-(1-azepanyl)-N-[4-(dimethylsulfamoyl)phenyl]acetamideHomo sapiens (human)Potency17.782820
2-chloro-N-[3-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-3-oxopropyl]benzamideHomo sapiens (human)Potency6.309620
[4-(4-bromo-2-chlorophenyl)sulfonyl-1-piperazinyl]-(2-sulfanylidene-1H-pyridin-3-yl)methanoneHomo sapiens (human)Potency10.000020
7-methyl-N-[4-(4-morpholinyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamideHomo sapiens (human)Potency14.125420
N-[3-[4-[(2-methoxyphenyl)sulfamoyl]anilino]-3-oxopropyl]-2-furancarboxamideHomo sapiens (human)Potency31.622820
1-[4-(benzenesulfonyl)-1-piperazinyl]-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]ethanoneHomo sapiens (human)Potency25.118920
3-[[2-(6-methoxy-3-benzofuranyl)-1-oxoethyl]amino]benzoic acid methyl esterHomo sapiens (human)Potency0.089120
2,2-dimethyl-N-pyridin-4-yl-3H-benzofuran-7-carboxamideHomo sapiens (human)Potency39.810720
N-[4-(5-oxazolyl)phenyl]benzamideHomo sapiens (human)Potency39.810720
5-(4-Methylphenyl)-1,3-oxazoleHomo sapiens (human)Potency28.183820
4-(2-fluorophenyl)-N-(2-methylbut-3-yn-2-yl)benzamideHomo sapiens (human)Potency6.309620
4-benzyl-N-(3,5-dichlorophenyl)-1,4-diazepane-1-carboxamideHomo sapiens (human)Potency39.810720
5-(4-morpholinylsulfonyl)-N-[4-(trifluoromethoxy)phenyl]-2-furancarboxamideHomo sapiens (human)Potency39.810720
1-(4-ethyl-2-pyridinyl)-3-(4-methylphenyl)sulfonylureaHomo sapiens (human)Potency2.818420
5-(tert-butyl)-2-methyl-N-(5-methyl-3-isoxazolyl)-3-furamideHomo sapiens (human)Potency39.810720
4-fluoro-N-[2-(1-piperidinyl)phenyl]benzenesulfonamideHomo sapiens (human)Potency28.183820
2-[(3-methoxyphenyl)-oxomethyl]-3,3-bis(methylthio)-2-propenenitrileHomo sapiens (human)Potency35.481320
1-(3-chloro-4-propan-2-ylsulfonyl-2-thiophenyl)-3-(3-nitrophenyl)ureaHomo sapiens (human)Potency25.118920
2-[5-[(3-chlorophenyl)thio]-2-thiophenyl]pyridineHomo sapiens (human)Potency39.810720
8-methylsulfinyl-4,5-dihydrothieno[3,4-g][2,1]benzoxazole-6-carboxylic acid ethyl esterHomo sapiens (human)Potency25.118920
2-[[2-methyl-5-nitro-3-(phenylmethyl)-4-imidazolyl]thio]-6-nitro-1H-benzimidazoleHomo sapiens (human)Potency28.183820
5-bromo-3-hydroxy-3-(4-methyl-1-piperidinyl)-1H-indol-2-oneHomo sapiens (human)Potency22.387220
[4-(2-methoxyphenyl)-1-piperazinyl]-[4-[(phenylthio)methyl]phenyl]methanoneHomo sapiens (human)Potency15.848920
1-(2-furanylmethyl)-3-[(4-methylphenyl)methyl]pyrrolidine-2,5-dioneHomo sapiens (human)Potency31.622820
2,6-dimethyl-4-thiophen-2-ylsulfonylmorpholineHomo sapiens (human)Potency39.810720
2-[[1-(4-methoxy-2-nitrophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]benzoic acidHomo sapiens (human)Potency19.952620
3-hydroxy-3-[2-oxo-2-[4-(1-pyrrolyl)phenyl]ethyl]-1H-indol-2-oneHomo sapiens (human)Potency14.125420
1-(3,4-dichlorophenyl)sulfonyl-4-[3-[(4-methyl-1,2,4-triazol-3-yl)thio]-4-nitrophenyl]piperazineHomo sapiens (human)Potency2.818420
3-(4-methoxyphenyl)-N-methyl-5-(4-methylphenyl)-3,4-dihydropyrazole-2-carbothioamideHomo sapiens (human)Potency22.387220
3-(2-furanyl)-3-(4-methylphenyl)-1-(4-morpholinyl)-1-propanoneHomo sapiens (human)Potency28.183820
3-fluoro-N-[4-[[4-(4-methoxyphenyl)-1-piperazinyl]-oxomethyl]phenyl]benzenesulfonamideHomo sapiens (human)Potency28.183820
4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrileHomo sapiens (human)Potency22.387220
[4-(benzenesulfonyl)-1-piperazinyl]-[6-bromo-2-(2-pyridinyl)-4-quinolinyl]methanoneHomo sapiens (human)Potency25.118920
6-(2-chlorophenyl)-3-methyl-2-[4-morpholinyl(oxo)methyl]-1,5,6,7-tetrahydroindol-4-oneHomo sapiens (human)Potency15.848920
1-butyl-2-[(1,3-dioxo-2-isoindolyl)methylthio]-5-benzimidazolesulfonamideHomo sapiens (human)Potency15.848920
1-thiophen-2-ylsulfonyl-4-piperidinecarboxylic acid 1,3-benzothiazol-2-ylmethyl esterHomo sapiens (human)Potency8.912520
2-[[(1-ethyl-2-benzimidazolyl)thio]methyl]-5-methyl-4-oxo-3H-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl esterHomo sapiens (human)Potency6.309620
N-(3-cyanophenyl)-2-(4-ethyl-2,5-dioxo-4-phenyl-1-imidazolidinyl)acetamideHomo sapiens (human)Potency3.981120
asterric acidHomo sapiens (human)Potency3.981120
2-[8-(6-amino-1H-benzimidazol-2-yl)octyl]-3H-benzimidazol-5-amineHomo sapiens (human)Potency17.782820
9-hydroxyiminofluorene-2,7-disulfonamideHomo sapiens (human)Potency3.981120
N-[[2-(4-chlorophenyl)-1,3-dioxo-7,7a-dihydro-3aH-octahydro-1H-4,7-epoxyisoindol-4-yl]methyl]benzenesulfonamideHomo sapiens (human)Potency28.183820
6-amino-5-cyano-2-phenyl-4-pyridin-4-yl-4H-pyran-3-carboxylic acid ethyl esterHomo sapiens (human)Potency39.810720
4-[[3-[(4-methylanilino)-oxomethyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl]amino]-4-oxobutanoic acidHomo sapiens (human)Potency28.183820
2-methoxy-N-[(4-methylphenyl)methyl]-2-phenylacetamideHomo sapiens (human)Potency39.810720
6-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideHomo sapiens (human)Potency0.631020
3-(4-fluorophenyl)-1-[(6-oxo-5H-[1,3]dioxolo[4,5-g]quinolin-7-yl)methyl]-1-(thiophen-2-ylmethyl)ureaHomo sapiens (human)Potency15.848920
2-[2-[[2-[[1-(2,4-dimethylphenyl)-5-tetrazolyl]thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl esterHomo sapiens (human)Potency14.125420
2-[[2-(1-benzotriazolyl)-1-oxoethyl]-(3-pyridinyl)amino]-2-(4-chlorophenyl)-N-(2-methoxyethyl)acetamideHomo sapiens (human)Potency39.810720
1-[2-[(3-cyano-5,7-dimethyl-2-quinolinyl)amino]ethyl]-3-(3-methoxypropyl)thioureaHomo sapiens (human)Potency28.183820
N-[2-[(3-cyano-8-methyl-2-quinolinyl)amino]ethyl]benzenesulfonamideHomo sapiens (human)Potency25.118920
5-(2-furanyl)-N-(3-pyridinylmethyl)-3-isoxazolecarboxamideHomo sapiens (human)Potency22.387220
1-methyl-4-[[2-oxo-2-[4-(2-pyridinyl)-1-piperazinyl]ethyl]thio]-2-quinolinoneHomo sapiens (human)Potency35.481320
N-(3-acetylphenyl)-3-(1-ethyl-3-methyl-4-pyrazolyl)-4,5-dihydroisoxazole-5-carboxamideHomo sapiens (human)Potency3.981120
2-[[4-cyano-3-[(2-methoxy-2-oxoethyl)thio]-5-isothiazolyl]thio]acetic acid ethenyl esterHomo sapiens (human)Potency14.125420
2-(6-benzimidazolo[1,2-c]quinazolinylthio)-N-(2-furanylmethyl)acetamideHomo sapiens (human)Potency10.000020
4-(4-methylphenyl)sulfonyl-4-oxanecarboxylic acid methyl esterHomo sapiens (human)Potency0.039820
N-[2-(2-methyl-1-indolyl)ethyl]benzamideHomo sapiens (human)Potency14.125420
N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,3-dimethoxyphenyl)acetamideHomo sapiens (human)Potency25.118920
3-[[5-bromo-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindol-7-yl]sulfonyl]-N-[(5-methyl-2-furanyl)methyl]propanamideHomo sapiens (human)Potency7.943320
6,7-dimethoxy-N-[(5-methyl-2-furanyl)methyl]-2-(2-methylpropyl)-1-oxo-4-isoquinolinecarboxamideHomo sapiens (human)Potency14.125420
2-(1-ethyl-4-oxo-3-furo[3,4]pyrrolo[3,5-c][1,2,4]triazinyl)-N-[4-(2-furanyl)butan-2-yl]propanamideHomo sapiens (human)Potency39.810720
1-[(2-ethoxyphenyl)methyl]-3-thiophen-2-ylureaHomo sapiens (human)Potency19.952620
N-[(S)-[(1S,2R)-1-methyl-2-[(2R)-1-[(5-methyl-2-furanyl)methylamino]-1-oxopropan-2-yl]cyclopropyl]-phenylmethyl]carbamic acid (phenylmethyl) esterHomo sapiens (human)Potency22.387220
3-(2-furanyl)-N-[3-(2-furanyl)-4-methylpentyl]-4-phenylbutanamideHomo sapiens (human)Potency35.481320
2-(3-thiophenyl)acetic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] esterHomo sapiens (human)Potency28.183820
4-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-3-nitrobenzenesulfonamideHomo sapiens (human)Potency19.952620
2-[(5-amino-1H-1,2,4-triazol-3-yl)thio]-N-(2-bromo-4-nitrophenyl)acetamideHomo sapiens (human)Potency3.162320
N,N,1-triethyl-2-sulfanylidene-3H-benzimidazole-5-sulfonamideHomo sapiens (human)Potency17.782820
5-(diethylsulfamoyl)-2-hydroxybenzoic acid [2-oxo-2-[4-(trifluoromethoxy)anilino]ethyl] esterHomo sapiens (human)Potency39.810720
N-(4-methylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamideHomo sapiens (human)Potency5.483520
2-[(1-methyl-3-indolyl)thio]-N-(2-thiazolyl)acetamideHomo sapiens (human)Potency0.891320
2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)-5-(4-morpholinylsulfonyl)phenyl]-4-quinolinecarboxamideHomo sapiens (human)Potency22.387220
2-[(4-amino-7-tert-butyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)thio]acetic acidHomo sapiens (human)Potency25.118920
LSM-1924Homo sapiens (human)Potency19.952620
1-(phenylmethyl)-4-(phenylmethylthio)pyrazolo[3,4-d]pyrimidineHomo sapiens (human)Potency5.011920
2-furanyl-[4-(4-propan-2-ylphenyl)sulfonyl-1-piperazinyl]methanoneHomo sapiens (human)Potency17.782820
3-[[4-(diphenylmethyl)-1-piperazinyl]-oxomethyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-oneHomo sapiens (human)Potency7.079520
2-[(4-hydroxy-3-nitrophenyl)sulfonylamino]benzoic acid [2-(4-methoxyphenyl)-2-oxoethyl] esterHomo sapiens (human)Potency39.810720
N-(1,3-dimethyl-2-oxo-5-benzimidazolyl)-4-fluoro-3-methylbenzenesulfonamideHomo sapiens (human)Potency19.952620
3-oxo-4H-1,4-benzothiazine-6-carboxylic acid [2-[1-(1-methoxypropan-2-yl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] esterHomo sapiens (human)Potency22.387220
N-butan-2-yl-2-[[3-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-4-oxo-2-quinazolinyl]thio]acetamideHomo sapiens (human)Potency39.810720
2-[[oxo-(2-oxo-1H-quinolin-4-yl)methyl]amino]-3-phenylpropanoic acid methyl esterHomo sapiens (human)Potency39.810720
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-piperidinecarboxylic acid [2-[2-chloro-5-(trifluoromethyl)anilino]-2-oxoethyl] esterHomo sapiens (human)Potency15.848920
2-(1H-indol-3-yl)-8-methylimidazo[1,2-a]pyridineHomo sapiens (human)Potency15.848920
N-(2-methoxy-4-nitrophenyl)-2-[(1-methyl-2-imidazolyl)thio]acetamideHomo sapiens (human)Potency12.589320
2-[[3-(3-oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acidHomo sapiens (human)Potency2.511920
3-hydroxy-6-(hydroxymethyl)-2-[(3-methoxyphenyl)-(2-pyridinylamino)methyl]-4-pyranoneHomo sapiens (human)Potency3.981120
[4-(butan-2-ylamino)-6-chloro-1,3,5-triazin-2-yl]-[(1,1,3-trioxo-1,2-benzothiazol-2-yl)methyl]cyanamideHomo sapiens (human)Potency35.481320
2-[(3-fluorophenyl)-(2-pyridinylamino)methyl]-3-hydroxy-6-(hydroxymethyl)-4-pyranoneHomo sapiens (human)Potency11.220220
N-cyclopentyl-2-(2,3-dihydroindol-1-yl)-2-(4-methoxyphenyl)acetamideHomo sapiens (human)Potency2.238720
2-(4-chlorophenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acidHomo sapiens (human)Potency39.810720
2-(4-methoxyphenyl)sulfonylquinoxalineHomo sapiens (human)Potency35.481320
3,5-diethyl-2-(2-hydroxyethylamino)-5-methyl-6H-benzo[h]quinazolin-4-oneHomo sapiens (human)Potency35.481320
N-[2-(3-methoxyanilino)-2-oxoethyl]-4-methylbenzamideHomo sapiens (human)Potency39.810720
7-[[2-(4-chloro-3,5-dimethyl-1-pyrazolyl)-1-oxoethyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidHomo sapiens (human)Potency25.118920
5-[3-(2-chloro-6-methoxy-3-quinolinyl)-5-(2-furanyl)-3,4-dihydropyrazol-2-yl]-5-oxopentanoic acidHomo sapiens (human)Potency22.387220
1-[(2-fluorophenyl)methyl]-4-pyrazolamineHomo sapiens (human)Potency15.848920
4-[(4-chlorophenyl)methylamino]-3-nitro-1-benzopyran-2-oneHomo sapiens (human)Potency0.891320
2-(2,3-dioxo-1-indolyl)-N-(2-phenylethyl)acetamideHomo sapiens (human)Potency31.622820
N-(2-bromo-4-nitrophenyl)-2-[(5-propan-2-yl-1H-1,2,4-triazol-3-yl)thio]acetamideHomo sapiens (human)Potency2.818420
acetic acid [2-[2-acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]phenyl] esterHomo sapiens (human)Potency28.183820
N-(1-dibutoxyphosphoryl-4-oxo-1-naphthalenyl)benzenesulfonamideHomo sapiens (human)Potency39.810720
N-[2-(4-methoxyphenyl)ethyl]-2-nitro-4-(1-pyrrolidinylsulfonyl)anilineHomo sapiens (human)Potency3.162320
4-[7-(2-methoxyethyl)-2,6-dioxo-3-(phenylmethyl)-8-purinyl]benzonitrileHomo sapiens (human)Potency25.118920
N-(3,4-dimethylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamideHomo sapiens (human)Potency0.408370
2-[[(3,5-dimethylphenyl)-oxomethyl]amino]acetic acid [2-[4-(2-naphthalenylsulfonyl)-1-piperazinyl]-2-oxoethyl] esterHomo sapiens (human)Potency25.118920
4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)benzoic acid [2-(cyclopropylamino)-2-oxoethyl] esterHomo sapiens (human)Potency28.183820
7-chloro-N-(phenylmethyl)-4-quinolinamineHomo sapiens (human)Potency15.848920
2-[[4-(2-methoxyphenyl)sulfonyl-1-piperazinyl]sulfonyl]benzonitrileHomo sapiens (human)Potency1.995320
N-[5-(diethylsulfamoyl)-2-methoxyphenyl]-5-methyl-3-isoxazolecarboxamideHomo sapiens (human)Potency39.810720
N-(2,5-difluorophenyl)-2-(1-pyrrolidinyl)acetamideHomo sapiens (human)Potency39.810720
N-(2-bromophenyl)-2-[5-(dimethylsulfamoyl)-2-(ethylamino)anilino]acetamideHomo sapiens (human)Potency39.810720
N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamideHomo sapiens (human)Potency2.818420
2-(4,5-dihydrothiazol-2-ylthio)-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]acetamideHomo sapiens (human)Potency28.183820
[4-[bis(4-morpholinyl)phosphoryl]-1-methyl-2-pyrrolyl]-bis(4-morpholinyl)-sulfanylidenephosphoraneHomo sapiens (human)Potency31.622820
3,7-dibutyl-3,7-dimethyl-2,6-dihydro-[1,2,4]triazolo[1,2-a][1,2,4]triazole-1,5-dithioneHomo sapiens (human)Potency19.952620
6-chloro-2-[(1H-1,2,4-triazol-5-ylthio)methyl]imidazo[1,2-a]pyridineHomo sapiens (human)Potency17.782820
santinHomo sapiens (human)Potency25.118920
rosmarinic acidHomo sapiens (human)Potency1.000020
4-hydroxyestradiolHomo sapiens (human)Potency0.112220
4-hydroxychalconeHomo sapiens (human)Potency19.952620
[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-[1,2,4]triazolo[4,3-a]quinoxalin-8-yl]-phenylmethanoneHomo sapiens (human)Potency0.316220
N-(3,5-dimethylphenyl)-2-[[4-(4-fluorophenyl)-5-[(1-methyl-2-pyrrolyl)methyl]-1,2,4-triazol-3-yl]thio]acetamideHomo sapiens (human)Potency12.589320
N-(3-fluoro-4-methylphenyl)-3-methyl-2-oxo-1,3-benzoxazole-6-sulfonamideHomo sapiens (human)Potency4.466820
N-(2,5-dimethoxyphenyl)-2-[[5-methyl-2-(2-methylphenyl)-4-oxazolyl]methylsulfonyl]acetamideHomo sapiens (human)Potency7.079520
1-(4-tert-butylphenyl)sulfonyl-N-(2-pyridinylmethyl)-2-piperidinecarboxamideHomo sapiens (human)Potency7.079520
N-(1,3-benzodioxol-5-yl)-2-(5-methyl-2-furanyl)-3-imidazo[1,2-a]pyrazinamineHomo sapiens (human)Potency10.000020
3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-oneHomo sapiens (human)Potency14.125420
6-methyl-3-(prop-2-enylthio)-5H-[1,2,4]triazino[5,6-b]indoleHomo sapiens (human)Potency3.548120
erbstatinHomo sapiens (human)Potency10.000020
styrylquinolineHomo sapiens (human)Potency14.125420
10H-phenanthro[9,10-g]pteridine-11,13-dioneHomo sapiens (human)Potency11.220220
dithiazanine iodideHomo sapiens (human)Potency25.118920
chloride of pseudoisocyanineHomo sapiens (human)Potency14.125420
Adenosine 5'-monophosphate monohydrateHomo sapiens (human)Potency6.375230
chaetoglobosin AHomo sapiens (human)Potency11.220220
2-(1-ethyl-4-pyrazolyl)-4-quinolinecarboxylic acidHomo sapiens (human)Potency25.118920
6-ethyl-8-methyl-N-(3-pyridinylmethyl)-3-benzo[b][1,4]benzothiazepinecarboxamideHomo sapiens (human)Potency35.481320
N-(3-methylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamideHomo sapiens (human)Potency2.907440
7-[(4-chlorophenyl)methylthio]-3-methyl-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-oneHomo sapiens (human)Potency14.125420
7-[(3-chlorophenyl)methylthio]-3-methyl-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-oneHomo sapiens (human)Potency3.548120
3-methyl-7-[(3-methylphenyl)methylthio]-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-oneHomo sapiens (human)Potency10.000020
N-(5-methyl-3-isoxazolyl)-2-[[6-(4-methylphenyl)-3-pyridazinyl]thio]acetamideHomo sapiens (human)Potency1.000020
2-[[6-(2-furanyl)-3-pyridazinyl]thio]-N-(3-methylphenyl)acetamideHomo sapiens (human)Potency3.162320
N-(4-fluorophenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamideHomo sapiens (human)Potency6.506410
2-(2,1,3-benzothiadiazol-4-ylsulfonyl)-5-(4-chlorophenyl)-3-pyrazolamineHomo sapiens (human)Potency25.118920
(3aR,4S,9aR,9bS)-N,2-bis(4-chlorophenyl)-1,3-dioxo-3a,4,9a,9b-tetrahydropyrrolo[1,2]pyrrolo[3,5-b]pyridazine-4-carboxamideHomo sapiens (human)Potency31.622820
hydralazine 4-anisaldehyde hydrazoneHomo sapiens (human)Potency39.810720
biapigeninHomo sapiens (human)Potency7.943320
(1S,2R)-2-[[4-[(2,4-dimethylphenyl)sulfamoyl]anilino]-oxomethyl]-1-cyclohexanecarboxylic acidHomo sapiens (human)Potency10.000020
N-[4-methyl-5-[2-(4-methylanilino)-4-thiazolyl]-2-thiazolyl]-2-furancarboxamideHomo sapiens (human)Potency25.118920
[4-(2-chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(phenylmethyl)-1-piperazinyl]methanoneHomo sapiens (human)Potency11.220220
1-(4-methylphenyl)-3-[[2-(4-methylphenyl)-1,3-dioxo-7,7a-dihydro-3aH-octahydro-1H-4,7-epoxyisoindol-4-yl]methyl]thioureaHomo sapiens (human)Potency15.848920
1-(3-chlorophenyl)-3-[[2-(4-methylphenyl)-1,3-dioxo-7,7a-dihydro-3aH-octahydro-1H-4,7-epoxyisoindol-4-yl]methyl]thioureaHomo sapiens (human)Potency22.387220
rabeprazole sodiumHomo sapiens (human)Potency28.183820
N-[3-[butyl(ethyl)amino]propyl]-2-[6-(4-morpholinylsulfonyl)-3-oxo-1,4-benzothiazin-4-yl]acetamideHomo sapiens (human)Potency31.622820
2-(2,5-difluorophenyl)-5-methyl-4-[[4-(2-pyrazinyl)-1-piperazinyl]methyl]oxazoleHomo sapiens (human)Potency35.481320
(3aS,5S,9aS)-2-[(2-methylphenyl)methyl]-5-(1-methyl-3-phenyl-4-pyrazolyl)-3a,4,5,7,8,9-hexahydro-3H-pyrrolo[3,4-h]pyrrolizin-1-oneHomo sapiens (human)Potency5.623420
N-[[2-(4-methylphenyl)-1,3-dioxo-7,7a-dihydro-3aH-octahydro-1H-4,7-epoxyisoindol-4-yl]methyl]-4-phenyl-1-piperazinecarbothioamideHomo sapiens (human)Potency19.952620
2-[(2-chloro-4-nitroanilino)methyl]-6-methoxyphenolHomo sapiens (human)Potency19.952620
[5-(4-bromophenyl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-pyridin-4-ylmethanoneHomo sapiens (human)Potency7.943320
(3aR,4S,9aR,9bS)-N-(4-chlorophenyl)-2-(4-fluorophenyl)-1,3-dioxo-3a,4,9a,9b-tetrahydropyrrolo[1,2]pyrrolo[3,5-b]pyridazine-4-carboxamideHomo sapiens (human)Potency19.952620
3-[4-[2-(2-fluorophenyl)ethylamino]-3-nitrophenyl]-3-[[2-(1-naphthalenyl)-1-oxoethyl]amino]propanamideHomo sapiens (human)Potency4.466820
(2,6-difluorophenyl)-[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1-piperazinyl]methanoneHomo sapiens (human)Potency71.271010
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-2-(1-piperidinyl)-1,3-benzothiazole-6-carboxamideHomo sapiens (human)Potency39.810720
N-(5-chloro-2,4-dimethoxyphenyl)-1-methyl-4-(4-morpholinylsulfonyl)-2-pyrrolecarboxamideHomo sapiens (human)Potency39.810720
N-(3,5-dimethoxyphenyl)-6-methyl-3-oxo-4H-1,4-benzoxazine-7-sulfonamideHomo sapiens (human)Potency7.079520
zinacefHomo sapiens (human)Potency7.079520
2-[(5-amino-7-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-3-yl)thio]-N-(4-chlorophenyl)acetamideHomo sapiens (human)Potency15.848920
N-[5-[[2-(4-acetamidoanilino)-2-oxoethyl]thio]-1,3,4-thiadiazol-2-yl]-5-bromo-2-furancarboxamideHomo sapiens (human)Potency19.952620
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(4-fluorophenyl)sulfonylpiperazineHomo sapiens (human)Potency0.128020
(2R)-4-(2,6-difluorophenyl)sulfonyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazineHomo sapiens (human)Potency1.601420
(2R)-1-(2,6-difluorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazineHomo sapiens (human)Potency3.038420
(2S)-4-(2,6-difluorophenyl)sulfonyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazineHomo sapiens (human)Potency4.292020
(2S)-1-(2,6-difluorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazineHomo sapiens (human)Potency6.992220
4-(2,6-difluorophenyl)sulfonyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperidineHomo sapiens (human)Potency0.200910
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(2-pyridinylsulfonyl)piperazineHomo sapiens (human)Potency1.661520
N-[1-(2,6-difluorophenyl)sulfonyl-4-piperidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency3.572010
1-(2,6-difluorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepaneHomo sapiens (human)Potency0.728720
N-[4-[(2,6-difluorophenyl)sulfonylamino]cyclohexyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency11.902610
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[3-(trifluoromethyl)phenyl]sulfonylpiperazineHomo sapiens (human)Potency1.465720
N-[[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-3-azetidinyl]methyl]-2,6-difluorobenzenesulfonamideHomo sapiens (human)Potency4.007910
N-[[1-(2,6-difluorophenyl)sulfonyl-3-azetidinyl]methyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency2.528810
N-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-3-pyrrolidinyl]-2,6-difluorobenzenesulfonamideHomo sapiens (human)Potency23.043220
N-[3-[(2,6-difluorophenyl)sulfonylamino]propyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency2.837410
N-[5-[(2,6-difluorophenyl)sulfonylamino]pentyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency2.008710
N-[6-[(2,6-difluorophenyl)sulfonylamino]hexyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency4.007910
N-[2-[(2,6-difluorophenyl)sulfonylamino]ethyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency20.086910
N-[1-(2,6-difluorophenyl)sulfonyl-3-pyrrolidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency12.710620
N-[4-[(2,6-difluorophenyl)sulfonylamino]butyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency5.045610
2,4-dimethyl-6-phenyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency30.384620
3-[(2-fluorophenyl)methyl]-5-methyl-4-thieno[3,4]pyrrolo[1,3-d]pyrimidinoneHomo sapiens (human)Potency21.510720
6-[(2-fluorophenyl)methyl]-2-(1-hydroxyethyl)-4-methyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency0.255620
6-[(3-methoxyphenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency0.183770
6-[(3-aminophenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency0.280970
2-bromo-6-[(2-chloro-6-fluorophenyl)methyl]-4-methyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency0.794310
2-bromo-6-[(2,4-difluorophenyl)methyl]-4-methyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency0.707910
3-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl]anilineHomo sapiens (human)Potency0.107150
N-butyl-5-(3,4-dimethylphenyl)-6H-1,3,4-thiadiazin-2-amineHomo sapiens (human)Potency25.118920
5-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazoleHomo sapiens (human)Potency22.387220