exp3174 has been researched along with Sensitivity and Specificity in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T | 1 |
| Chai, Y; Ma, W; Sun, S; Wang, B; Yuan, Y; Zhang, G; Zhang, H; Zhao, L | 1 |
| Kundlik, ML; Patel, CN; Patel, DM; Patel, NK; Shah, HJ; Subbaiah, G; Suhagia, BN | 1 |
| Apostolou, C; Dotsikas, Y; Kolocouri, F; Kousoulos, C; Loukas, YL | 1 |
| Furtek, CI; Lo, MW; Ritter, MA | 1 |
| Fakhry, I; Farthing, D; Gehr, TW; Pedro, A; Sica, D | 1 |
| Mutschler, E; Soldner, A; Spahn-Langguth, H | 1 |
| Mutschler, E; Palm, D; Soldner, A; Spahn-Langguth, H | 1 |
| Hara, K; Iwasa, T; Kamei, T; Takano, T | 1 |
1 trial(s) available for exp3174 and Sensitivity and Specificity
| Article | Year |
|---|---|
A radioreceptor assay for the analysis of AT1-receptor antagonists. Correlation with complementary LC data reveals a potential contribution of active metabolites.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Proteins; Chromatography, High Pressure Liquid; Double-Blind Method; Humans; Imidazoles; Losartan; Male; Placebos; Pyrimidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin; Reference Values; Sensitivity and Specificity; Tetrazoles | 1998 |
8 other study(ies) available for exp3174 and Sensitivity and Specificity
| Article | Year |
|---|---|
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents | 2011 |
Influence of compound danshen tablet on the pharmacokinetics of losartan and its metabolite EXP3174 by liquid chromatography coupled with mass spectrometry.
Topics: Animals; Chromatography, Liquid; Drug Stability; Drugs, Chinese Herbal; Herb-Drug Interactions; Imidazoles; Losartan; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salvia miltiorrhiza; Sensitivity and Specificity; Tetrazoles | 2013 |
Rapid determination of losartan and losartan acid in human plasma by multiplexed LC-MS/MS.
Topics: Acids; Antihypertensive Agents; Chromatography, Liquid; Humans; Hydroflumethiazide; Imidazoles; Losartan; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tetrazoles | 2009 |
Simultaneous determination of losartan, EXP-3174 and hydrochlorothiazide in plasma via fully automated 96-well-format-based solid-phase extraction and liquid chromatography-negative electrospray tandem mass spectrometry.
Topics: Antihypertensive Agents; Chemical Fractionation; Drug Combinations; Drug Monitoring; Humans; Hydrochlorothiazide; Imidazoles; Losartan; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tetrazoles | 2007 |
An improved method for the simultaneous determination of losartan and its major metabolite, EXP3174, in human plasma and urine by high-performance liquid chromatography with fluorescence detection.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Chromatography, High Pressure Liquid; Humans; Imidazoles; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Tetrazoles | 1997 |
Simple high-performance liquid chromatographic method for determination of losartan and E-3174 metabolite in human plasma, urine and dialysate.
Topics: Antihypertensive Agents; Chromatography, High Pressure Liquid; Dialysis Solutions; Humans; Imidazoles; Kidney Failure, Chronic; Losartan; Peritoneal Dialysis, Continuous Ambulatory; Sensitivity and Specificity; Tetrazoles | 1997 |
HPLC assays to simultaneously determine the angiotensin-AT1 antagonist losartan as well as its main and active metabolite EXP 3174 in biological material of humans and rats.
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Chromatography, High Pressure Liquid; Humans; Imidazoles; Losartan; Rats; Receptors, Angiotensin; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tetrazoles; Tissue Distribution | 1998 |
Method for the simultaneous determination of losartan and its major metabolite, EXP-3174, in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Antihypertensive Agents; Chromatography, Liquid; Drug Stability; Humans; Imidazoles; Losartan; Mass Spectrometry; Quality Control; Sensitivity and Specificity; Tetrazoles | 1999 |