technetium Tc 99m depreotide: Tc-99m-labeled somatostatin [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
ID Source | ID |
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PubMed CID | 72941733 |
MeSH ID | M0411109 |
Synonym |
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174900-52-8 |
technetium tc 99m depreotide |
technetium tc-99m depreotide |
neotect |
neotec |
technetium-99tc, (cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl)(1-1')-sulfide with 3-((mercaptoacetyl)amino)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamidato(3-))oxo-, (sp-5-24)- |
unii-9m48m2sf02 |
9m48m2sf02 , |
tc-99m depreotide |
technetium-99tc, (cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl) (1-1')-thioether with 3-((mercaptoacetyl)amino)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamidato(3-))oxo-, (sp-5-24)- |
technetium tc 99m depreotide [usp impurity] |
technetium tc-99m depreotide [orange book] |
technetium tc 99m depreotide [who-dd] |
neo tect kit |
Q27272728 |
technetium tc 99m depreotide (usp impurity) |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (1.47) | 18.2507 |
2000's | 60 (88.24) | 29.6817 |
2010's | 6 (8.82) | 24.3611 |
2020's | 1 (1.47) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 13 (17.81%) | 5.53% |
Reviews | 8 (10.96%) | 6.00% |
Case Studies | 20 (27.40%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 32 (43.84%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Substance | Relationship Strength | Studies | Trials | Classes | Roles |
---|---|---|---|---|---|
pentetic acid Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium. | 3.52 | 2 | 0 | pentacarboxylic acid | copper chelator |
edetic acid Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive. | 2.03 | 1 | 0 | ethylenediamine derivative; polyamino carboxylic acid; tetracarboxylic acid | anticoagulant; antidote; chelator; copper chelator; geroprotector |
technetium Technetium: The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, and atomic number 43. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years. | 3.51 | 2 | 0 | manganese group element atom | |
thallium chloride thallium chloride: RN given refers to unlabeled parent cpd | 2.42 | 2 | 0 | inorganic chloride; thallium molecular entity | |
gallium citrate [no description available] | 3.53 | 2 | 0 | ||
3-iodobenzylguanidine 3-Iodobenzylguanidine: A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase. | 3.11 | 1 | 0 | organoiodine compound | |
edda EDDA: RN given refers to parent cpd. ethylenediaminediacetic acid : An ethylenediamine derivative in which two of the four amine protons of ethylenediamine are replaced by carboxymethyl groups. | 2.03 | 1 | 0 | amino dicarboxylic acid; ethylenediamine derivative; glycine derivative; polyamino carboxylic acid | bacterial xenobiotic metabolite; chelator |
fluorodeoxyglucose f18 Fluorodeoxyglucose F18: The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162) | 8.47 | 13 | 3 | 2-deoxy-2-((18)F)fluoro-D-glucose; 2-deoxy-2-fluoro-aldehydo-D-glucose | |
yttrium radioisotopes Yttrium Radioisotopes: Unstable isotopes of yttrium that decay or disintegrate emitting radiation. Y atoms with atomic weights 82-88 and 90-96 are radioactive yttrium isotopes. | 4.07 | 1 | 0 | ||
technetium tc 99m hydroxymethylene diphosphonate technetium Tc 99m hydroxymethylene diphosphonate: bone-seeking radiopharmaceutical | 2.02 | 1 | 0 | ||
technetium tc 99m pentetate Technetium Tc 99m Pentetate: A technetium imaging agent used in renal scintigraphy, computed tomography, lung ventilation imaging, gastrointestinal scintigraphy, and many other procedures which employ radionuclide imaging agents. | 2.71 | 3 | 0 | ||
thallium Thallium: A heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.. thallium : A metallic element first identified and named from the brilliant green line in its flame spectrum (from Greek thetaalphalambdalambdaomicronsigma, a green shoot). | 2.42 | 2 | 0 | boron group element atom | |
gallium Gallium: A rare, metallic element designated by the symbol, Ga, atomic number 31, and atomic weight 69.72.. gallium atom : A metallic element predicted as eka-aluminium by Mendeleev in 1870 and discovered by Paul-Emile Lecoq de Boisbaudran in 1875. Named in honour of France (Latin Gallia) and perhaps also from the Latin gallus cock, a translation of Lecoq. | 3.53 | 2 | 0 | boron group element atom | |
(dtpa-phe(1))-octreotide SDZ 215-811: potential radiopharmaceutical for imaging of somatostatin receptor-positive tumors | 3.11 | 1 | 0 | ||
technetium tc 99m sestamibi Technetium Tc 99m Sestamibi: A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack. | 3.11 | 1 | 0 | ||
technetium tc 99m medronate Technetium Tc 99m Medronate: A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms. | 4.32 | 4 | 1 | ||
technetium tc-99m tetrofosmin [no description available] | 2.01 | 1 | 0 | ||
lutetium lu 177 dotatate 177Lu-DOTA-octreotate: an somatostatin receptor agonist | 2.02 | 1 | 0 |
Condition | Indicated | Relationship Strength | Studies | Trials |
---|---|---|---|---|
Coin Lesion, Pulmonary [description not available] | 0 | 7.71 | 20 | 1 |
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 9.77 | 26 | 10 |
Carcinoma, Non-Small Cell Lung [description not available] | 0 | 4.05 | 5 | 0 |
Cancer of Lung [description not available] | 0 | 10.22 | 38 | 7 |
Carcinoma, Non-Small-Cell Lung A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. | 0 | 4.05 | 5 | 0 |
Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 10.22 | 38 | 7 |
Congenital Thrombotic Thrombocytopenic Purpura [description not available] | 0 | 2.04 | 1 | 0 |
Purpura, Thrombotic Thrombocytopenic An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases. | 0 | 2.04 | 1 | 0 |
Carcinoma, Bronchial [description not available] | 0 | 2.71 | 3 | 0 |
Lymph Node Metastasis [description not available] | 0 | 3.82 | 2 | 1 |
Carcinoma, Bronchogenic Malignant neoplasm arising from the epithelium of the BRONCHI. It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA. | 0 | 2.71 | 3 | 0 |
Cancer of Digestive System [description not available] | 0 | 3.89 | 1 | 0 |
Digestive System Neoplasms Tumors or cancer of the DIGESTIVE SYSTEM. | 0 | 3.89 | 1 | 0 |
Neuroendocrine Tumors Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition. | 0 | 4.74 | 2 | 0 |
Recrudescence [description not available] | 0 | 2.05 | 1 | 0 |
Germinoblastoma [description not available] | 0 | 3.82 | 2 | 1 |
Lymphoma A general term for various neoplastic diseases of the lymphoid tissue. | 0 | 3.82 | 2 | 1 |
Disease, Pulmonary [description not available] | 0 | 6.13 | 6 | 2 |
Lung Diseases Pathological processes involving any part of the LUNG. | 0 | 6.13 | 6 | 2 |
Carcinoma, Epidermoid [description not available] | 0 | 2.01 | 1 | 0 |
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 2.01 | 1 | 0 |
Cancer of Eye [description not available] | 0 | 2.01 | 1 | 0 |
Benign Meningeal Neoplasms [description not available] | 0 | 2.01 | 1 | 0 |
Angioblastic Meningioma [description not available] | 0 | 2.01 | 1 | 0 |
Local Neoplasm Recurrence [description not available] | 0 | 2.71 | 3 | 0 |
Meningeal Neoplasms Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord. | 0 | 2.01 | 1 | 0 |
Meningioma A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7) | 0 | 2.01 | 1 | 0 |
Neoplasms, Squamous Cell Neoplasms of the SQUAMOUS EPITHELIAL CELLS. The concept does not refer to neoplasms located in tissue composed of squamous elements. | 0 | 2.01 | 1 | 0 |
Injuries, Radiation [description not available] | 0 | 2.01 | 1 | 0 |
Basedow Disease [description not available] | 0 | 3.11 | 5 | 0 |
Graves Disease A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy). | 0 | 3.11 | 5 | 0 |
Brill-Symmers Disease [description not available] | 0 | 2.01 | 1 | 0 |
Lymphoma, Follicular Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. The nodules resemble to some extent the GERMINAL CENTER of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-LYMPHOCYTES. | 0 | 2.01 | 1 | 0 |
Breast Cancer [description not available] | 0 | 5.71 | 7 | 3 |
Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 5.71 | 7 | 3 |
Metastase [description not available] | 0 | 3.34 | 2 | 0 |
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 3.34 | 2 | 0 |
Adenocarcinoma Of Kidney [description not available] | 0 | 2.02 | 1 | 0 |
Cancer of Kidney [description not available] | 0 | 2.02 | 1 | 0 |
Carcinoma, Renal Cell A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma. | 0 | 2.02 | 1 | 0 |
Kidney Neoplasms Tumors or cancers of the KIDNEY. | 0 | 2.02 | 1 | 0 |
Carcinoma, Anaplastic [description not available] | 0 | 4.66 | 3 | 2 |
Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 4.66 | 3 | 2 |
Bone Cancer [description not available] | 0 | 4.88 | 4 | 2 |
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES. | 0 | 4.88 | 4 | 2 |
Diffuse Mixed Small and Large Cell Lymphoma [description not available] | 0 | 3.4 | 1 | 1 |
Lymphoma, Non-Hodgkin Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. | 0 | 3.4 | 1 | 1 |
Besnier-Boeck Disease [description not available] | 0 | 2.02 | 1 | 0 |
Sarcoidosis An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands. | 0 | 2.02 | 1 | 0 |
Innate Inflammatory Response [description not available] | 0 | 2.02 | 1 | 0 |
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 2.02 | 1 | 0 |
Carcinoma, Oat Cell [description not available] | 0 | 2.93 | 4 | 0 |
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.02 | 1 | 0 |
Experimental Neoplasms [description not available] | 0 | 2.02 | 1 | 0 |
Carcinoma, Small Cell An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7) | 0 | 2.93 | 4 | 0 |
Cancer of the Thyroid [description not available] | 0 | 4.11 | 3 | 1 |
Carcinoma, Papillary, Follicular A thyroid neoplasm of mixed papillary and follicular arrangement. Its biological behavior and prognosis is the same as that of a papillary adenocarcinoma of the thyroid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1271) | 0 | 2.03 | 1 | 0 |
Thyroid Neoplasms Tumors or cancer of the THYROID GLAND. | 0 | 4.11 | 3 | 1 |
Follicular Thyroid Carcinoma [description not available] | 0 | 3.41 | 1 | 1 |
Carcinoma, Papillary A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed) | 0 | 3.41 | 1 | 1 |
Adenocarcinoma, Follicular An adenocarcinoma of the thyroid gland, in which the cells are arranged in the form of follicles. (From Dorland, 27th ed) | 0 | 3.41 | 1 | 1 |
Leucocythaemia [description not available] | 0 | 2.03 | 1 | 0 |
Leukemia A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 2.03 | 1 | 0 |
Benign Neoplasms [description not available] | 0 | 3.34 | 2 | 0 |
Cancer of Pancreas [description not available] | 0 | 2.03 | 1 | 0 |
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 3.34 | 2 | 0 |
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 2.03 | 1 | 0 |
Bone Inflammation [description not available] | 0 | 2.04 | 1 | 0 |
Osteomyelitis INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA. | 0 | 2.04 | 1 | 0 |
Hamartoma A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area. | 0 | 3.43 | 1 | 1 |
Experimental Lung Inflammation Inflammation of any part, segment or lobe, of the lung parenchyma. | 0 | 3.43 | 1 | 1 |
Pneumonia Infection of the lung often accompanied by inflammation. | 0 | 3.43 | 1 | 1 |
Adenocarcinoma, Basal Cell [description not available] | 0 | 2.41 | 2 | 0 |
Adenocarcinoma A malignant epithelial tumor with a glandular organization. | 0 | 2.41 | 2 | 0 |
Cell Transformation, Neoplastic Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. | 0 | 2.01 | 1 | 0 |
Soft Tissue Neoplasms Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc. | 0 | 2.01 | 1 | 0 |
Atelectasis [description not available] | 0 | 2.01 | 1 | 0 |
Pulmonary Consumption [description not available] | 0 | 2.92 | 1 | 0 |
AIDS-Related Opportunistic Infections Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus. | 0 | 2.92 | 1 | 0 |
Tuberculosis, Pulmonary MYCOBACTERIUM infections of the lung. | 0 | 2.92 | 1 | 0 |