thioctic acid has been researched along with Sensitivity and Specificity in 26 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The utility of the assay was confirmed by pharmacokinetic study of N2L in rats." | 1.40 | Determination of newly synthesized lipoic acid-niacin dimer in rat plasma by UPLC/electrospray ionization tandem mass spectrometry: assay development, validation and application to a pharmacokinetic study. ( Chen, X; Gao, J; Huang, P; Jiang, Y; Pi, R; Xie, Y; Yao, M; Zhu, S, 2014) |
| "Treatment with coenzyme Q10 plus alpha-lipoic acid significantly restored contractile responses to all forms of stimulation." | 1.35 | The beneficial effect of coenzyme Q10 and lipoic acid on obstructive bladder dysfunction in the rabbit. ( Chuang, SM; Huang, CH; Hydery, T; Juan, YS; Kogan, B; Levin, RM; Li, S; Mannikarottu, A; Schuler, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 9 (34.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, T | 1 |
| Zhang, W | 1 |
| Sun, Y | 1 |
| Shuai, Z | 1 |
| Chida, AS | 1 |
| Kenny, TP | 1 |
| Yang, GX | 1 |
| Sanz, I | 1 |
| Ansari, A | 1 |
| Bowlus, CL | 1 |
| Ippolito, GC | 1 |
| Coppel, RL | 2 |
| Okazaki, K | 1 |
| He, XS | 1 |
| Leung, PSC | 1 |
| Gershwin, ME | 2 |
| Chen, X | 1 |
| Gao, J | 1 |
| Jiang, Y | 1 |
| Huang, P | 1 |
| Xie, Y | 1 |
| Pi, R | 1 |
| Zhu, S | 1 |
| Yao, M | 1 |
| Bayram, B | 1 |
| Rimbach, G | 1 |
| Frank, J | 1 |
| Esatbeyoglu, T | 1 |
| Shen, Y | 1 |
| Zhang, Y | 1 |
| Liu, M | 1 |
| Liu, X | 1 |
| Guo, H | 1 |
| Zhang, X | 2 |
| Zhang, C | 1 |
| Li, H | 1 |
| Yao, S | 1 |
| Xiong, H | 1 |
| Zheng, H | 1 |
| Wang, W | 1 |
| Liang, J | 1 |
| Wen, W | 1 |
| Wang, S | 1 |
| Satoh, S | 1 |
| Shindoh, M | 1 |
| Min, JZ | 1 |
| Toyo'oka, T | 1 |
| Fukushima, T | 1 |
| Inagaki, S | 1 |
| Juan, YS | 1 |
| Levin, RM | 1 |
| Chuang, SM | 1 |
| Hydery, T | 1 |
| Li, S | 1 |
| Kogan, B | 1 |
| Schuler, C | 1 |
| Huang, CH | 1 |
| Mannikarottu, A | 1 |
| Sato, M | 1 |
| Ito, Y | 1 |
| Arima, N | 1 |
| Baba, M | 1 |
| Sobel, M | 1 |
| Wakao, M | 1 |
| Suda, Y | 1 |
| Ji, X | 1 |
| Nakamura, T | 1 |
| Siangproh, W | 1 |
| Rattanarat, P | 1 |
| Chailapakul, O | 1 |
| Khan, A | 2 |
| Iqbal, Z | 1 |
| Watson, DG | 1 |
| Khan, I | 1 |
| Muhammad, N | 1 |
| Muhammad, S | 1 |
| Nasib, HA | 1 |
| Iqbal, N | 1 |
| Kashif, M | 1 |
| Sun, J | 1 |
| Guo, L | 1 |
| Bao, Y | 1 |
| Xie, J | 1 |
| Montero, O | 1 |
| Ramírez, M | 1 |
| Sánchez-Guijo, A | 1 |
| González, C | 1 |
| Arivazhagan, P | 1 |
| Panneerselvam, SR | 1 |
| Panneerselvam, C | 1 |
| Trivedi, RK | 1 |
| Kallem, RR | 1 |
| Mamidi, RN | 1 |
| Mullangi, R | 1 |
| Srinivas, NR | 1 |
| Fragoso, A | 1 |
| Almirall, E | 1 |
| Cao, R | 1 |
| Echegoyen, L | 1 |
| González-Jonte, R | 1 |
| Cataldi, TR | 1 |
| Nardiello, D | 1 |
| Durrani, AI | 1 |
| Schwartz, H | 1 |
| Schmid, W | 1 |
| Sontag, G | 1 |
| Tharakan, B | 1 |
| Holder-Haynes, JG | 1 |
| Hunter, FA | 1 |
| Childs, EW | 1 |
| Teichert, J | 1 |
| Preiss, R | 1 |
| Moteki, S | 1 |
| Leung, PS | 1 |
| Dickson, ER | 1 |
| Kaplan, MM | 1 |
| Munoz, S | 1 |
| Witt, W | 1 |
| Rüstow, B | 1 |
| Sen, CK | 1 |
| Roy, S | 1 |
| Packer, L | 1 |
| Baker, H | 1 |
| DeAngelis, B | 1 |
| Baker, ER | 1 |
| Hutner, SH | 1 |
| Haj-Yehia, AI | 1 |
| Assaf, P | 1 |
| Nassar, T | 1 |
| Katzhendler, J | 1 |
| Conlon, BJ | 1 |
| Smith, DW | 1 |
26 other studies available for thioctic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
Autoreactive monoclonal antibodies from patients with primary biliary cholangitis recognize environmental xenobiotics.
Topics: Antibodies, Monoclonal; Autoantigens; Autoimmunity; Cholangitis; Female; Gene Amplification; Humans; | 2017 |
Determination of newly synthesized lipoic acid-niacin dimer in rat plasma by UPLC/electrospray ionization tandem mass spectrometry: assay development, validation and application to a pharmacokinetic study.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Male; Niacin; Rats; Rats, Wistar; Rep | 2014 |
Rapid method for glutathione quantitation using high-performance liquid chromatography with coulometric electrochemical detection.
Topics: Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Drug Stability; Electrochemical Techni | 2014 |
A simple and sensitive electrochemical immunosensor based on thiol aromatic aldehyde as a substrate for the antibody immobilization.
Topics: Antibodies, Immobilized; Benzaldehydes; Calibration; Electrochemical Techniques; Electrodes; Equipme | 2015 |
A convenient purification method for silver nanoclusters and its applications in fluorescent pH sensors for bacterial monitoring.
Topics: Bacterial Typing Techniques; Colorimetry; Equipment Design; Equipment Failure Analysis; Escherichia | 2016 |
Selective and sensitive determination of lipoyllysine (protein-bound alpha-lipoic acid) in biological specimens by high-performance liquid chromatography with fluorescence detection.
Topics: Animals; Chromatography, High Pressure Liquid; Fluorescence; Fluorescent Dyes; Lysine; Male; Mass Sp | 2008 |
The beneficial effect of coenzyme Q10 and lipoic acid on obstructive bladder dysfunction in the rabbit.
Topics: Analysis of Variance; Animals; Blotting, Western; Disease Models, Animal; Dose-Response Relationship | 2008 |
High-sensitivity analysis of naturally occurring sugar chains, using a novel fluorescent linker molecule.
Topics: Amination; Chromatography, High Pressure Liquid; Disaccharides; Fluorescent Dyes; Humans; Immunoglob | 2009 |
Amperometric sensor for hydrogen peroxide based on immobilized cytochrome c on binary self-assembled monolayers.
Topics: Amides; Animals; Biocatalysis; Biosensing Techniques; Cytochromes c; Electric Impedance; Electrochem | 2009 |
Reverse-phase liquid chromatographic determination of α-lipoic acid in dietary supplements using a boron-doped diamond electrode.
Topics: Boron; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Diamond; Dietary Supplem | 2010 |
Simultaneous determination of lipoic acid (LA) and dihydrolipoic acid (DHLA) in human plasma using high-performance liquid chromatography coupled with electrochemical detection.
Topics: Adult; Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Stability; Electrochemical | 2011 |
A simple, label-free AuNPs-based colorimetric ultrasensitive detection of nerve agents and highly toxic organophosphate pesticide.
Topics: Chemical Warfare Agents; Colorimetry; Gold; Metal Nanoparticles; Organophosphorus Compounds; Pestici | 2011 |
Determination of lipoic acid, Trolox methyl ether and tocopherols in human plasma by liquid-chromatography and ion-trap tandem mass spectrometry.
Topics: Chromans; Chromatography, High Pressure Liquid; Humans; Linear Models; Reproducibility of Results; S | 2012 |
Effect of DL-alpha-lipoic acid on the status of lipid peroxidation and lipids in aged rats.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Antioxidants; Lipid Peroxidation; Male; Models, A | 2003 |
Determination of lipoic acid in rat plasma by LC-MS/MS with electrospray ionization: assay development, validation and application to a pharamcokinetic study.
Topics: Animals; Calibration; Chromatography, Liquid; Male; Rats; Rats, Wistar; Reproducibility of Results; | 2004 |
A supramolecular approach to the selective detection of dopamine in the presence of ascorbate.
Topics: Ascorbic Acid; beta-Cyclodextrins; Dopamine; Electrochemistry; Electrodes; Gold; Sensitivity and Spe | 2004 |
A pulsed potential waveform displaying enhanced detection capabilities towards sulfur-containing compounds at a gold working electrode.
Topics: Acetylcysteine; Biotin; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine | 2005 |
alpha-Lipoic acid in dietary supplements: development and comparison of HPLC-CEAD and HPLC-ESI-MS methods.
Topics: Antioxidants; Calibration; Chromatography, High Pressure Liquid; Dietary Supplements; Electrodes; Li | 2007 |
Alpha lipoic acid attenuates microvascular endothelial cell hyperpermeability by inhibiting the intrinsic apoptotic signaling.
Topics: Analysis of Variance; Animals; Apoptosis; Capillary Permeability; Caspase 3; Cell Membrane Permeabil | 2008 |
Determination of lipoic acid in human plasma by high-performance liquid chromatography with electrochemical detection.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Quality Control; Reproducibility of | 1995 |
Use of a designer triple expression hybrid clone for three different lipoyl domain for the detection of antimitochondrial autoantibodies.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Autoantibodies; Autoantigens; Base Seque | 1996 |
Determination of lipoic acid by precolumn derivatization with monobromobimane and reversed-phase high-performance liquid chromatography.
Topics: Animals; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Fluorescent Dyes; Humans; | 1998 |
Flow cytometric determination of cellular thiols.
Topics: Bridged Bicyclo Compounds; Flow Cytometry; Fluorescent Dyes; Glutathione; Humans; Jurkat Cells; Lymp | 1999 |
Protozoological method for assaying lipoate in human biologic fluids and tissue.
Topics: Animals; Biological Assay; Humans; Liver; Photometry; Sensitivity and Specificity; Tetrahymena therm | 1999 |
Determination of lipoic acid and dihydrolipoic acid in human plasma and urine by high-performance liquid chromatography with fluorimetric detection.
Topics: Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Sensitivity and Specificit | 2000 |
Topical aminoglycoside ototoxicity: attempting to protect the cochlea.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Auditory Perception; Cochlear Diseases; Dru | 2000 |