Page last updated: 2024-11-04

risedronic acid and Sensitivity and Specificity

risedronic acid has been researched along with Sensitivity and Specificity in 7 studies

Risedronic Acid: A pyridine and diphosphonic acid derivative that acts as a CALCIUM CHANNEL BLOCKER and inhibits BONE RESORPTION.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"Six postmenopausal women with diagnosed osteopenia/osteoporosis received a single oral dose of 100 nCi 41Ca for skeleton labeling."2.73Evaluation of 41calcium as a new approach to assess changes in bone metabolism: effect of a bisphosphonate intervention in postmenopausal women with low bone mass. ( Denk, E; Fattinger, K; Häuselmann, HJ; Hillegonds, D; Hurrell, RF; Kraenzlin, M; Vogel, J; Walczyk, T, 2007)
"This study was designed to develop a sensitive and rapid method for the quantitation of risedronate in human urine using ultra-performance liquid chromatography with ultra-violet detector (UPLC-UV) and to compare bioavailability parameter of 5, 35 and 150 mg risedronate."1.40UPLC-UV method for determination of risedronate in human urine. ( Chung, YH; Jeong, JH; Lim, CH; Seo, YH, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seo, YH1
Chung, YH1
Lim, CH1
Jeong, JH1
Wasserfallen, JB1
Krieg, MA1
Greiner, RA1
Lamy, O1
Ghassabian, S1
Wright, LA1
Dejager, AD1
Smith, MT1
Thomson, AB1
Appleman, S1
Keelan, M1
Wallace, JL1
Vallano, PT1
Shugarts, SB1
Kline, WF1
Woolf, EJ1
Matuszewski, BK1
Zhu, LS1
Lapko, VN1
Lee, JW1
Basir, YJ1
Kafonek, C1
Olsen, R1
Briscoe, C1
Denk, E1
Hillegonds, D1
Hurrell, RF1
Vogel, J1
Fattinger, K1
Häuselmann, HJ1
Kraenzlin, M1
Walczyk, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparative Study of Calcium Metabolism in Caucasian and Asian Postmenopausal Women of Chinese Descent and the Use of Strontium as a Qualitative Marker of Calcium Metabolism in Humans[NCT02565602]10 participants (Actual)Interventional2014-02-28Completed
Using Ca-41 Methodology to Assess the Impact of Different Vitamin D Supplementation Levels on Postmenopausal Bone Health[NCT01053481]Early Phase 125 participants (Actual)Interventional2010-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for risedronic acid and Sensitivity and Specificity

ArticleYear
Role of gastric mucosal and gastric juice cytokine concentrations in development of bisphosphonate damage to gastric mucosa.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:2

    Topics: Administration, Oral; Aged; Alendronate; Biomarkers; Biopsy, Needle; Cytokines; Dinoprostone; Dose-R

2003
Evaluation of 41calcium as a new approach to assess changes in bone metabolism: effect of a bisphosphonate intervention in postmenopausal women with low bone mass.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:10

    Topics: Aged; Biomarkers; Bone Density; Bone Diseases, Metabolic; Calcium Radioisotopes; Diphosphonates; Eti

2007
Evaluation of 41calcium as a new approach to assess changes in bone metabolism: effect of a bisphosphonate intervention in postmenopausal women with low bone mass.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:10

    Topics: Aged; Biomarkers; Bone Density; Bone Diseases, Metabolic; Calcium Radioisotopes; Diphosphonates; Eti

2007
Evaluation of 41calcium as a new approach to assess changes in bone metabolism: effect of a bisphosphonate intervention in postmenopausal women with low bone mass.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:10

    Topics: Aged; Biomarkers; Bone Density; Bone Diseases, Metabolic; Calcium Radioisotopes; Diphosphonates; Eti

2007
Evaluation of 41calcium as a new approach to assess changes in bone metabolism: effect of a bisphosphonate intervention in postmenopausal women with low bone mass.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:10

    Topics: Aged; Biomarkers; Bone Density; Bone Diseases, Metabolic; Calcium Radioisotopes; Diphosphonates; Eti

2007

Other Studies

5 other studies available for risedronic acid and Sensitivity and Specificity

ArticleYear
UPLC-UV method for determination of risedronate in human urine.
    Journal of chromatographic science, 2014, Volume: 52, Issue:7

    Topics: Adult; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Etidronic Acid

2014
Cost effectiveness and cost utility of risedronate for osteoporosis treatment and fracture prevention in women: a Swiss perspective.
    Journal of medical economics, 2008, Volume: 11, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Bone Density Conservation Agents; Cost-Benefit Analysis; Etidr

2008
Development and validation of a sensitive solid-phase-extraction (SPE) method using high-performance liquid chromatography/tandem mass spectrometry (LC-MS/MS) for determination of risedronate concentrations in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Jan-15, Volume: 881-882

    Topics: Acetaminophen; Chromatography, High Pressure Liquid; Diazomethane; Drug Stability; Etidronic Acid; H

2012
Determination of risedronate in human urine by column-switching ion-pair high-performance liquid chromatography with ultraviolet detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Aug-25, Volume: 794, Issue:1

    Topics: Chromatography, High Pressure Liquid; Etidronic Acid; Humans; Ions; Reference Standards; Reproducibi

2003
A general approach for the quantitative analysis of bisphosphonates in human serum and urine by high-performance liquid chromatography/tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2006, Volume: 20, Issue:22

    Topics: Alendronate; Bone Density Conservation Agents; Chromatography, High Pressure Liquid; Diazomethane; E

2006