nicotine has been researched along with Sensitivity and Specificity in 159 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 31 (19.50) | 18.2507 |
| 2000's | 98 (61.64) | 29.6817 |
| 2010's | 29 (18.24) | 24.3611 |
| 2020's | 1 (0.63) | 2.80 |
| Authors | Studies |
|---|---|
| Allende-Richter, S; Brogna, M; Collins, J; Fuller, A; Hubbard, Z; Kline, M; Levy, S; Lewis, M; McCormack, J; Menzin, E; Minegishi, M; Mitchell, SG; Subramaniam, G; Weiss, R; Weitzman, E | 1 |
| Cucullo, L; Kaisar, MA; Kallem, RR; Sajja, RK; Sifat, AE | 1 |
| Farhadi, S; Ghiasvand, A; Koonani, S; Yazdankhah, F | 1 |
| Inukai, T; Kaji, S; Kataoka, H | 1 |
| Achilihu, H; Bernert, JT; Feng, J; Wang, L | 1 |
| Du, J; Liu, Y; Mei, S; Qin, Y; Shi, Y; Zhang, D; Zhao, Z | 1 |
| Kot-Wasik, A; Kubica, P; Namieśnik, J; Wasik, A | 1 |
| Alenus, J; Cleij, TJ; Csipai, P; Ethirajan, A; Gruber, J; Horemans, F; Peeters, M; Wagner, P; Weustenraed, A | 1 |
| Kane, CJ; Loprinzi, PD; Walker, JF | 1 |
| Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Tam, LM | 1 |
| Gilch, G; Piller, M; Scherer, G; Scherer, M | 1 |
| Close, L; Lee, AH; Rahmati, R; Stater, BJ | 1 |
| Abdallah, IA; Hammell, DC; Hassan, HE; Stinchcomb, AL | 1 |
| Aldhous, MC; Prescott, RJ; Roberts, S; Samuel, K; Satsangi, J; Waterfall, M | 1 |
| Collins, GE; Copper, CL; Newman, CI | 1 |
| Inoue, R; Kataoka, H; Saito, K; Yagi, K | 1 |
| Benowitz, NL; Bernert, JT; Caraballo, RS; Holiday, DB; Wang, J | 1 |
| Al-Ghananeem, AM; Crooks, PA; de Leon, J; Malkawi, AH | 1 |
| Awang, R; Harn, GL; Ismail, S; Lajis, R; Man, CN | 1 |
| Chen, JG; Chen, PY; Ho, KC; Suryanarayanan, V; Wu, CT | 1 |
| Kemmei, T; Kodama, S; Morikawa, A; Nakagomi, K; Sato, A; Suzuki, K; Taga, A; Yamamoto, A; Yamashita, T | 1 |
| Corstjens, P; Mauk, M; Niedbala, RS; Volkov, A | 1 |
| Arruda, MA; de Oliveira, DM; de Siqueira, ME; Figueiredo, EC | 1 |
| Gharaibeh, AA; Massadeh, AM; Omari, KW | 1 |
| Huestis, MA; Shakleya, DM | 3 |
| Szumska, M; Tyrpień, K; Wielkoszyński, T | 1 |
| Merfort, I; Millet, A; Stintzing, F | 1 |
| Blank, MD; Disharoon, S; Eissenberg, T | 1 |
| Baumann, F; Burgos-Guerrero, IL; Hegerl, U; Preiss, R; Regenthal, R | 1 |
| Howick, J | 1 |
| Axelsson, BO; Axén, J; Malmström, D; Petersson, P; Sjöberg, PJ | 1 |
| Goto, M; Ito, R; Iwasaki, Y; Makino, T; Mochizuki, K; Nakazawa, H; Saito, K; Sugino, N; Terayama, E | 1 |
| Bose, D; Chin-Chen, ML; Durgavanshi, A; Esteve-Romero, J; Rambla-Alegre, M | 1 |
| Apinan, R; Choemung, A; Na-Bangchang, K | 1 |
| Daneshfar, A; Kardani, F; Sahrai, R | 1 |
| Bieber, NM; Bourdelle, PA; Foley, MW; Gonzalez, JM; Niedbala, RS | 1 |
| Onoue, S; Seto, Y; Yamada, S; Yamamoto, N | 1 |
| Alexander, RR; Bernert, JT; Xia, Y; Xu, M | 1 |
| Kaiserman, MJ; Levasseur, G; Yeh, E | 1 |
| Fleckenstein, AE; Miller, EI; Nielsen, SM; Vieira-Brock, PL; Wilkins, DG | 1 |
| Ansermot, N; Choong, E; Cornuz, J; Dobrinas, M; Eap, CB; Noetzli, M | 1 |
| Chang, KS; Chen, CD; Chen, YT; Chiang, PL; Chou, AC; Hung, HH; Liang, C; Lin, MC; Pan, CY; Sun, CJ; Yeh, YH | 1 |
| Barroso, M; Calheiros, J; da Fonseca, BM; Gallardo, E; Magalhães, AR; Moreno, IE; Queiroz, JA; Ravara, S | 1 |
| Huestis, MA; Scheidweiler, KB; Shakleya, DM | 1 |
| Cooley, J; Lopez-Avila, V; Thevis, M; Urdahl, R | 1 |
| De Cremer, K; Van Loco, J; Van Overmeire, I | 1 |
| Hecht, SS | 1 |
| Bisson, MA; Gong, XQ | 1 |
| Bye, A; Gomeni, R; Iavarone, L; Milleri, S; Squassante, L; Teneggi, V | 1 |
| Benowitz, NL; Hall, S; Hatsukami, D; Jacob, P; Severson, H; Yu, L | 1 |
| Girod, R; Jareb, M; Moss, J; Role, L | 1 |
| Hatsukami, DK; Hecht, SS; Hennrikus, DJ; Joseph, AM; Pentel, PR | 1 |
| Bryant, A; Erens, B; Feyerabend, C; Jarvis, MJ; Primatesta, P | 1 |
| Conway, TL; Edwards, CC; Hovell, MF; Woodruff, SI | 1 |
| Hackett, LP; Hale, TW; Ilett, KF; Kristensen, JH; Page-Sharp, M | 1 |
| Benowitz, NL; Jacob, P; Pomerleau, CS; Pomerleau, OF | 1 |
| Heishman, SJ; Moolchan, ET; Singleton, EG | 1 |
| Baidoo, EE; Clench, MR; Smith, RF; Tetler, LW | 1 |
| Bisoen Rambali, A; Hogendoorn, EA; Niesing, W; Stolker, AL; Vleeming, W | 1 |
| Diaz, D; Garcia-Algar, O; Pacifici, R; Pascual, JA; Pichini, S; Segura, J; Vall, O; Zuccaro, P | 1 |
| Collins, AC; Hutton, SR; Marks, MJ; McCallum, SE; Paylor, R; Tritto, T; Waddle, SA | 1 |
| Doctor, PB; Gokani, VN; Kulkarni, PK; Parikh, JR; Saiyed, HN | 1 |
| Albuquerque, EX; Almeida, LE; Camara, AL; Maelicke, A; Pereira, EF | 1 |
| Asnafi-Farhang, S; Diviné, C; Lagrue, G; Larramendy, C | 1 |
| Mustonen, T | 1 |
| Hickcox, M; Shiffman, S; Waters, A | 1 |
| Brown, K; Drury, M; Johnstone, E; Murphy, M; Roberts, K; Saunders, C; Walton, R | 1 |
| Okayama, A; Sato, T | 1 |
| Chang, MS; El-Shourbagy, TA; Gregg, H; Kim, GE; Swaine, BA; Wagdy, A; Xu, N | 1 |
| Moshammer, H; Nebot, M; Neuberger, M | 1 |
| Baker, KM; Bonn-Miller, MO; Brown, RA; Feldner, MT; Leen-Feldner, E; Zvolensky, MJ | 1 |
| Iba, MM; Weisel, CP; Xu, X | 1 |
| Ahmad, S; Gage, E; Moore, R; Savage, JM; Tengs, TO | 1 |
| Darwin, WD; Huestis, MA; Kim, I | 1 |
| Koide, M; Namba, H; Nishizawa, S; Terakawa, S; Yamaguchi, M; Yamamoto, S | 1 |
| Heavner, DL; Morgan, WT; Ogden, MW; Richardson, JD | 1 |
| Barrueco, M; Jiménez Ruiz, C; Palomo, L; Riesco, JA; Romero, P; Torrecilla, M | 1 |
| Byrd, GD; Davis, RA; Ogden, MW | 1 |
| Gomez, C; Marquis, P | 1 |
| Felt-Bersma, RJ; Kuipers, EJ; Sloots, CE; West, RL | 1 |
| Chang, YL; Chou, YC; Tien, JH; Tsai, PL; Tsai, TH | 1 |
| Collins, PW; Ingram, JR; Newcombe, RG; Rhodes, J; Thomas, GA; Williams, GT | 1 |
| Cooney, NL; McKee, SA; O'Malley, SS; Toll, BA | 1 |
| Naidong, W; Shou, WZ | 1 |
| Fidente, P; Morrica, P; Seccia, S; Vanni, F | 1 |
| Akhter, MP; Andrianifahanana, M; Batra, SK; Brand, RE; Cullen, DM; Johansson, SL; Pandey, KK; Prokopczyk, B; Wittel, UA | 1 |
| De Nardi, C; Meneses-Lorente, G; Sakatis, MZ; Schulz-Utermoehl, T; Watt, AP | 1 |
| Matsuzaki, H; Nemoto, Y; Nishimura, T; Oda, H; Okawa, A; Tokuhasi, Y; Uematu, Y | 1 |
| Huestis, MA; Kim, I | 1 |
| Goodz, SD; Malaiyandi, V; Sellers, EM; Tyndale, RF | 1 |
| Feuer, R; Hatsukami, D; Hecht, SS; Jensen, J; Stepanov, I | 1 |
| Anand, JS; Galer-Tatarowicz, K; Korolkiewicz, R; Morkowska, A; Nowak-Banasik, L; Szpiech, B; Wiergowski, M | 1 |
| Ahluwalia, JS; Cox, LS; Etter, JF; Kaur, H; Mayo, MS; Nazir, N; Okuyemi, KS; Pulvers, KM; Thomas, JL | 1 |
| Hayashida, M; Jinno, K; Ogawa, M; Saito, Y; Ueta, I | 1 |
| Glover, ED; Glover, PN; Laflin, MT; Nochur, SV; Strnad, JV | 1 |
| Briggs, CA; Gopalakrishnan, M; Grønlien, JH; Håkerud, M; Malysz, J; Thorin-Hagene, K; Ween, H | 1 |
| Benowitz, NL; Hecht, SS; Jacob, P; Lindgren, B; Stepanov, I; Wilson, M | 1 |
| Durgbanshi, A; García-Algar, O; Marchei, E; Pellegrini, M; Pichini, S; Rossi, S; Vagnarelli, F; Vall, O | 1 |
| Ho, SW; Murphy, SE; Villalta, P; von Weymarn, LB | 1 |
| Einarson, TR; Ferrence, R; Florescu, A; Grossman, L; Jacqz-Aigrain, E; Koren, G; Kramer, M; Rankin, A; Selby, P; Woodruff, S | 1 |
| Delnevo, CD; Steinberg, MB | 1 |
| Montalto, NJ; Wells, WO | 1 |
| Bornstein, NM; Candale, C; Csiba, L; Molnár, S; Oláh, L; Raiter, Y; Rosengarten, B | 1 |
| Gu, SY; Li, L; Li, YQ; Liu, CQ; Ma, SJ; Yang, GH; Yang, XQ | 1 |
| Babovic-Vuksanovic, D; Heidbreder, CA; Shippenberg, TS; Shoaib, M | 1 |
| Khan, IM; Taylor, P; Yaksh, TL | 2 |
| Imamura, T; Kimura, K; Kudo, K; Nagata, T; Urakawa, N | 1 |
| del Castillo, J; Morales, M; Sierra, C; Smith, DS; Vidal, A | 1 |
| Birbaumer, N; Eggstein, M; Lingenfelser, T; Overkamp, D; Pickert, A; Pickert, C | 1 |
| Alink, GM; Brouwer, A; Dohmen, MJ; Heussen, GA; Schefferlie, GJ; Talsma, MJ; van Til, H | 1 |
| Lasalde, JA; McNamee, MG; Ochoa, EL; Vibat, CR | 1 |
| Colditz, GA; Delea, TE; Huse, DM; Oster, G; Regan, MM | 1 |
| McGhan, WF; Smith, MD | 1 |
| Fiene, JA; Havel, JA; Hulse, JD; Peng, LL; Petersen, ME; Xu, AS | 1 |
| Marcus, M; Nisell, M; Nomikos, GG; Svensson, TH | 1 |
| Nyström, L; Pettersson, M; Rångemark, C | 1 |
| Bickler, PE; Eilers, H; Forsayeth, JR; Schaeffer, E | 1 |
| Ellard, GA; Mather, HM; Smith, RF | 1 |
| Lu, GH; Ralapati, S | 1 |
| Cirimele, V; Henrich, A; Kintz, P; Ludes, B | 1 |
| James, H; Taylor, R; Tizabi, Y | 1 |
| Oddoze, C; Pastor, J; Pauli, AM | 1 |
| Ho, JW; Leung, YK | 1 |
| Albuquerque, EX; Conti-Fine, BM; Cortes, WS; Horton, RM; Karachunski, PI; Macklin, K; Maus, AD; Navaneetham, D; Pereira, EF | 1 |
| Anderson, R; Croghan, IT; Dale, LC; Hurt, RD; Ji, AJ; Lawson, GM | 1 |
| Lowin, A; Russell, MA; Stapleton, JA | 1 |
| Katoh, T; Kawamoto, T; Kitagawa, K; Kunugita, N; Yang, M | 1 |
| Francis, MM; Horenstein, B; Papke, RL; Porter, JK; Robinson, G; Stokes, C; Webster, JC | 1 |
| Marks, JL; Namenek, RJ; Pomerleau, CS; Pomerleau, OF | 1 |
| Kelley, BM; Middaugh, LD | 1 |
| Hill, DJ; Schofield, PE | 1 |
| Pragst, F; Sporkert, F | 1 |
| Ginevan, ME; Graves, CG; Jenkins, RA; LaKind, JS; Naiman, DQ; Tardiff, RG | 1 |
| Fuller, SG; Stepans, MB | 1 |
| Kuroiwa, Y; Nakajima, M; Yamamoto, T; Yokoi, T | 1 |
| Sweanor, D | 1 |
| Bates, C | 1 |
| Brock, G; Chapple, I; Cope, G; Holder, R; Nayyar, P | 1 |
| Cope, G; Holder, R; Nayyar, P; Wilkinson, L | 1 |
| Audrain, J; Boyd, NR; Caporaso, NE; Falk, RT; Issaq, HJ; Lerman, C; Main, D; Shields, P; Utermahlan, B | 1 |
| Cohen, P; Eliakim, R; Heyman, SN; Karmeli, F; Rachmilewitz, D | 1 |
| Al-Delaimy, W; Mahoney, GN | 1 |
| Chen, YL; Jiang, X; Naidong, W; Shou, W | 1 |
| Liang, C; Nie, L; Peng, H; Tan, Y; Yao, S; Yin, J | 1 |
| Bächmann, K; Bazzanella, A; Kropsch, S; Lochmann, H | 1 |
| David, SP | 1 |
| Abou-Donia, MB; Abu-Qare, AW | 2 |
| Etter, JF; Perneger, TV | 1 |
| Grando, SA | 1 |
| Burkhart, CG; Burkhart, CN | 1 |
| Al-Delaimy, WK; Crane, J; Woodward, A | 1 |
| Balfour, DJ | 1 |
| Jee, SH; Kim, JG; Shin, HS; Shin, YJ | 1 |
| Kolonen, SA; Puhakainen, EV | 1 |
7 review(s) available for nicotine and Sensitivity and Specificity
| Article | Year |
|---|---|
Are e-cigarettes effective in smoking cessation?
Topics: Electronic Nicotine Delivery Systems; Evidence-Based Medicine; Female; Humans; Longitudinal Studies; Male; Nicotine; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Smoking; Smoking Cessation; Tobacco Use Cessation Devices; Treatment Outcome | 2015 |
Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention.
Topics: Animals; Carcinogens; Chemoprevention; Disease Susceptibility; Female; Humans; Lung Neoplasms; Male; Models, Animal; Nicotiana; Nicotine; Primary Prevention; Prognosis; Research; Risk Assessment; Risk Factors; Rodentia; Sensitivity and Specificity; Smoking | 2002 |
[Usefulness of biological markers in evaluation of smoking].
Topics: Air; Alkaloids; Artifacts; Biomarkers; Carbon Monoxide; Carboxyhemoglobin; Chromatography; Colorimetry; Cotinine; Evaluation Studies as Topic; False Positive Reactions; Follow-Up Studies; Humans; Immunoassay; Nicotine; Saliva; Sensitivity and Specificity; Smoking; Thiocyanates | 2004 |
[The neurobiology of nicotine addiction].
Topics: Adaptation, Physiological; Dopamine; Humans; Neurobiology; Neurotransmitter Agents; Nicotine; Receptors, Cholinergic; Risk Factors; Sensitivity and Specificity; Smoking; Smoking Cessation; Tobacco Use Disorder | 2004 |
[How should markers of smoking be used during pregnancy?].
Topics: Biomarkers; Carbon Monoxide; Cotinine; Female; Humans; Nicotine; Pregnancy; Sensitivity and Specificity; Smoking | 2005 |
Reference values for hair cotinine as a biomarker of active and passive smoking in women of reproductive age, pregnant women, children, and neonates: systematic review and meta-analysis.
Topics: Adult; Biomarkers; Child; Child, Preschool; Cotinine; Female; Hair; Humans; Infant; Infant, Newborn; Inhalation Exposure; Maternal Exposure; Maternal-Fetal Exchange; Nicotine; Pregnancy; Radioimmunoassay; Reference Values; Sensitivity and Specificity; Smoking; Tobacco Smoke Pollution | 2007 |
The neurobiology of tobacco dependence: a commentary.
Topics: Bupropion; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Male; Neurobiology; Nicotine; Nucleus Accumbens; Sensitivity and Specificity; Smoking; Smoking Cessation; Smoking Prevention; Tobacco Use Disorder | 2002 |
11 trial(s) available for nicotine and Sensitivity and Specificity
| Article | Year |
|---|---|
Assessment of Screening Tools to Identify Substance Use Disorders Among Adolescents.
Topics: Adolescent; Child; Cross-Sectional Studies; Ethanol; Female; Humans; Mass Screening; Nicotine; Sensitivity and Specificity; Substance-Related Disorders | 2023 |
Comparison of methods for measurement of smoking behavior: mouthpiece-based computerized devices versus direct observation.
Topics: Adult; Carbon Monoxide; Environmental Monitoring; Equipment Design; Female; Humans; Male; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking; Tobacco Smoke Pollution | 2009 |
Correlation and predictive performances of saliva and plasma nicotine concentration on tobacco withdrawal-induced craving.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Predictive Value of Tests; Saliva; Sensitivity and Specificity; Smoking; Substance Withdrawal Syndrome | 2002 |
Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy.
Topics: Adult; Alkaloids; Anabasine; Biomarkers; Chewing Gum; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nicotine; Probability; Prospective Studies; Pyridines; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Smoking; Tobacco Use Cessation; Tobacco Use Disorder; Tobacco, Smokeless; Treatment Outcome | 2002 |
Nicotine metabolite ratio as a predictor of cigarette consumption.
Topics: Adult; Biomarkers; Cotinine; Female; Ganglionic Stimulants; Humans; Male; Middle Aged; Nicotine; Predictive Value of Tests; Sensitivity and Specificity; Smoking; Tobacco Use Disorder | 2003 |
Tobacco Craving Questionnaire: reliability and validity of a new multifactorial instrument.
Topics: Adult; Affect; Female; Ganglionic Stimulants; Humans; Male; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking Cessation; Surveys and Questionnaires; Tobacco Use Disorder | 2003 |
Plasma fibrinogen in ulcerative colitis: the effect of disease activity and nicotine therapy in a randomised controlled trial.
Topics: Colitis, Ulcerative; Enema; Female; Fibrinogen; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Sensitivity and Specificity; Sigmoidoscopy | 2005 |
Do daily interactive voice response reports of smoking behavior correspond with retrospective reports?
Topics: Data Collection; Double-Blind Method; Female; Humans; Male; Mental Recall; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Patient Compliance; Self Disclosure; Sensitivity and Specificity; Smoking; Smoking Cessation; Telephone; Time Factors | 2005 |
Visually evoked cerebral vasomotor response in smoking and nonsmoking young adults, investigated by functional transcranial Doppler.
Topics: Adolescent; Adult; Analysis of Variance; Arteries; Blood Flow Velocity; Brain; Carbon Dioxide; Cerebral Arteries; Cerebrovascular Circulation; Echoencephalography; Evoked Potentials, Visual; Female; Humans; Male; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking; Ultrasonography, Doppler, Transcranial; Vasomotor System; Visual Cortex | 2008 |
A new gas chromatography-mass spectrometry method for simultaneous determination of total and free trans-3'-hydroxycotinine and cotinine in the urine of subjects receiving transdermal nicotine.
Topics: Administration, Cutaneous; Cotinine; Gas Chromatography-Mass Spectrometry; Humans; Nicotine; Nicotinic Agonists; Sensitivity and Specificity; Smoking; Smoking Cessation | 1999 |
Nicotine metabolism and CYP2D6 phenotype in smokers.
Topics: Adult; Cotinine; Cytochrome P-450 CYP2D6; Female; Genetic Markers; Genotype; Humans; Male; Nicotine; Phenotype; Polymorphism, Genetic; Reference Values; Risk Assessment; Sensitivity and Specificity; Smoking | 2001 |
141 other study(ies) available for nicotine and Sensitivity and Specificity
| Article | Year |
|---|---|
A convenient UHPLC-MS/MS method for routine monitoring of plasma and brain levels of nicotine and cotinine as a tool to validate newly developed preclinical smoking model in mouse.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cotinine; Mice; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking; Tandem Mass Spectrometry | 2017 |
A comparison study on a sulfonated graphene-polyaniline nanocomposite coated fiber for analysis of nicotine in solid samples through the traditional and vacuum-assisted HS-SPME.
Topics: Aniline Compounds; Flame Ionization; Ganglionic Stimulants; Graphite; Hair; Humans; Limit of Detection; Male; Microscopy, Electron, Scanning; Nanocomposites; Nicotiana; Nicotine; Porosity; Sensitivity and Specificity; Solid Phase Microextraction; Stainless Steel; Temperature; Tobacco Products; Vacuum | 2018 |
Analysis of nicotine and cotinine in hair by on-line in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry as biomarkers of exposure to tobacco smoke.
Topics: Adult; Biomarkers; Chromatography, High Pressure Liquid; Cotinine; Female; Hair; Healthy Volunteers; Humans; Limit of Detection; Male; Middle Aged; Nicotine; Sensitivity and Specificity; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tobacco Smoke Pollution; Young Adult | 2018 |
Tobacco Use Classification by Inexpensive Urinary Cotinine Immunoassay Test Strips.
Topics: Calibration; Chromatography, Liquid; Cotinine; Humans; Nicotine; Reagent Strips; Sensitivity and Specificity; Smoking; Tandem Mass Spectrometry | 2019 |
Simultaneous determination of plasma nicotine and cotinine by UHPLC-MS/MS in C57BL/6 mice and its application in a pharmacokinetic study.
Topics: Animals; Chromatography, High Pressure Liquid; Cotinine; Linear Models; Male; Mice; Mice, Inbred C57BL; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2019 |
"Dilute & shoot" approach for rapid determination of trace amounts of nicotine in zero-level e-liquids by reversed phase liquid chromatography and hydrophilic interactions liquid chromatography coupled with tandem mass spectrometry-electrospray ionization
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Hydrophobic and Hydrophilic Interactions; Nicotine; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tobacco Products | 2013 |
Molecularly imprinted polymers as synthetic receptors for the QCM-D-based detection of L-nicotine in diluted saliva and urine samples.
Topics: Biosensing Techniques; Humans; Molecular Imprinting; Molecular Structure; Nicotine; Saliva; Sensitivity and Specificity; Urine | 2013 |
Do nicotine intake and acute heart rate response to smoking rank nicotine dependence the same?
Topics: Heart Rate; Humans; Male; Nicotine; Pilot Projects; Sensitivity and Specificity; Smoking; Tobacco Use Disorder | 2013 |
Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions.
Topics: Adenine; Adult; Biomarkers; Chromatography, Liquid; Cotinine; DNA Methylation; Guanine; Humans; Limit of Detection; Nicotine; Nitrosamines; Pyridines; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites.
Topics: Chromatography, Liquid; Humans; Linear Models; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2014 |
A fully validated LC-MS/MS method for simultaneous determination of nicotine and its metabolite cotinine in human serum and its application to a pharmacokinetic study after using nicotine transdermal delivery systems with standard heat application in adul
Topics: Chromatography, Liquid; Cotinine; Drug Stability; Humans; Hyperthermia, Induced; Linear Models; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking Cessation; Tandem Mass Spectrometry; Tobacco Use Cessation Devices; Tobacco Use Disorder | 2016 |
Does nicotine influence cytokine profile and subsequent cell cycling/apoptotic responses in inflammatory bowel disease?
Topics: Adolescent; Adult; Aged; Analysis of Variance; Apoptosis; Biomarkers; Cell Cycle; Cells, Cultured; Child; Colitis, Ulcerative; Crohn Disease; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inflammatory Bowel Diseases; Leukocytes, Mononuclear; Male; Middle Aged; Multivariate Analysis; Nicotine; Probability; Reference Values; Sensitivity and Specificity; Smoking; Young Adult | 2008 |
Simple and rapid extraction, separation, and detection of alkaloids in beverages.
Topics: Aconitine; Alkaloids; Animals; Beverages; Chromatography, Micellar Electrokinetic Capillary; Colchicine; Food Contamination; Humans; Molecular Structure; Nicotine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Strychnine | 2008 |
Determination of nicotine, cotinine, and related alkaloids in human urine and saliva by automated in-tube solid-phase microextraction coupled with liquid chromatography-mass spectrometry.
Topics: Alkaloids; Anabasine; Chromatography, Liquid; Cotinine; Humans; Mass Spectrometry; Nicotine; Online Systems; Saliva; Sensitivity and Specificity; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2009 |
Optimal serum cotinine levels for distinguishing cigarette smokers and nonsmokers within different racial/ethnic groups in the United States between 1999 and 2004.
Topics: Adolescent; Adult; Biomarkers; Child; Clinical Laboratory Techniques; Cotinine; Female; Humans; Male; Nicotine; Reference Values; ROC Curve; Sensitivity and Specificity; Smoking; Surveys and Questionnaires; Tobacco Smoke Pollution; United States; Young Adult | 2009 |
Nicotine exposure can be detected in cerebrospinal fluid of active and passive smokers.
Topics: Biomarkers; Child; Chromatography, Liquid; Cotinine; Female; Humans; Infant; Infant, Newborn; Mass Spectrometry; Maternal Exposure; Maternal-Fetal Exchange; Molecular Structure; Nicotine; Pregnancy; Reference Standards; Sensitivity and Specificity; Smoking; Time Factors; Tobacco Smoke Pollution | 2009 |
Determination of hair nicotine by gas chromatography-mass spectrometry.
Topics: Gas Chromatography-Mass Spectrometry; Hair; Humans; Least-Squares Analysis; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking; Tobacco Smoke Pollution; Young Adult | 2009 |
Detection of nicotine based on molecularly imprinted TiO2-modified electrodes.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cotinine; Electrochemistry; Electrodes; Humans; Microscopy, Scanning Probe; Nicotine; Polymers; Sensitivity and Specificity; Spectroscopy, Fourier Transform Infrared; Surface Properties; Swine; Time Factors; Titanium | 2009 |
Enantioseparation of nicotine alkaloids in cigarettes by CE using sulfated beta-CD as a chiral selector and a capillary coated with amino groups.
Topics: Alkaloids; Amines; Cotinine; Electrophoresis, Capillary; Humans; Nicotiana; Nicotine; Sensitivity and Specificity; Stereoisomerism; Sulfates | 2009 |
Rapid prototyping of lateral flow assays.
Topics: Biosensing Techniques; Chromatography; Equipment Design; Equipment Failure Analysis; Immunoassay; Nicotine; Pilot Projects; Point-of-Care Systems; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity | 2009 |
On-line molecularly imprinted solid-phase extraction for the selective spectrophotometric determination of nicotine in the urine of smokers.
Topics: Buffers; Calibration; Humans; Hydrogen-Ion Concentration; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking; Spectrophotometry; Temperature | 2009 |
A single-step extraction method for the determination of nicotine and cotinine in Jordanian smokers' blood and urine samples by RP-HPLC and GC-MS.
Topics: Chromatography, High Pressure Liquid; Cotinine; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Jordan; Nicotine; Sensitivity and Specificity; Smoking; Uncertainty | 2009 |
Simultaneous quantification of nicotine, opioids, cocaine, and metabolites in human fetal postmortem brain by liquid chromatography tandem mass spectrometry.
Topics: Analgesics, Opioid; Brain; Chromatography, Liquid; Cocaine; Humans; Nicotine; Sensitivity and Specificity; Tandem Mass Spectrometry | 2009 |
The enzyme-linked immunosorbent assay (ELISA) method for nicotine metabolites determination in biological fluids.
Topics: Animals; Antibodies, Monoclonal; Calibration; Chromatography, Thin Layer; Cotinine; Densitometry; Enzyme-Linked Immunosorbent Assay; Male; Nicotine; Rabbits; Reference Standards; Sensitivity and Specificity; Smoking | 2009 |
Validation of a GC-FID method for rapid quantification of nicotine in fermented extracts prepared from Nicotiana tabacum fresh leaves and studies of nicotine metabolites.
Topics: Calibration; Fermentation; Gas Chromatography-Mass Spectrometry; Models, Biological; Nicotiana; Nicotine; Plant Leaves; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solutions; Temperature; Time Factors | 2009 |
Simultaneous and sensitive measurement of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Cotinine; Humans; Nicotine; Sensitivity and Specificity; Tandem Mass Spectrometry | 2009 |
Optimization and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human oral fluid.
Topics: Chromatography, Liquid; Cotinine; Gingival Crevicular Fluid; Humans; Mass Spectrometry; Nicotine; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Determination of nicotine and cotinine in human serum by means of LC/MS.
Topics: Chromatography, Liquid; Cotinine; Drug Stability; Humans; Linear Models; Mass Spectrometry; Nicotine; Sensitivity and Specificity; Solid Phase Extraction; Specimen Handling | 2010 |
Questioning the methodologic superiority of 'placebo' over 'active' controlled trials.
Topics: Chewing Gum; Controlled Clinical Trials as Topic; Data Interpretation, Statistical; Double-Blind Method; Drug Synergism; Ethics, Clinical; Ethics, Medical; Ethics, Research; Hippocratic Oath; Humans; Moral Obligations; Nicotine; Physician-Patient Relations; Placebo Effect; Placebos; Randomized Controlled Trials as Topic; Research Design; Research Personnel; Research Subjects; Researcher-Subject Relations; Sample Size; Sensitivity and Specificity; Smoking Cessation | 2009 |
Efforts to improve detection sensitivity for capillary electrophoresis coupled to atmospheric pressure photoionization mass spectrometry.
Topics: Albuterol; Electrophoresis, Capillary; Mass Spectrometry; Nicotine; Procainamide; Sensitivity and Specificity | 2010 |
Development and validation of a hydrophilic interaction chromatography-tandem mass spectrometry for quantification of nicotine and its metabolites in human maternal and cord sera.
Topics: Chromatography, Affinity; Female; Fetal Blood; Humans; Hydrophobic and Hydrophilic Interactions; Nicotine; Pregnancy; Reproducibility of Results; Sensitivity and Specificity; Smoking; Solid Phase Extraction; Tandem Mass Spectrometry | 2011 |
Rapid and sensitive determination of nicotine in formulations and biological fluid using micellar liquid chromatography with electrochemical detection.
Topics: Chewing Gum; Chromatography, Micellar Electrokinetic Capillary; Electrochemical Techniques; Humans; Hydrogen-Ion Concentration; Least-Squares Analysis; Nicotine; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Tobacco Use Cessation; Transdermal Patch | 2010 |
A sensitive HPLC-ESI-MS-MS method for the determination of cotinine in urine.
Topics: Acetaminophen; Adult; Chromatography, High Pressure Liquid; Cotinine; Drug Stability; Female; Humans; Linear Models; Male; Middle Aged; Nicotine; Polymethacrylic Acids; Polyvinyls; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tobacco Use Cessation Devices | 2010 |
Determination of nicotine, anabasine, and cotinine in urine and saliva samples using single-drop microextraction.
Topics: Anabasine; Chromatography, Liquid; Cotinine; Humans; Hydrogen-Ion Concentration; Linear Models; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Sodium Chloride; Solid Phase Microextraction; Time Factors | 2010 |
Development of an ultrasensitive immunochromatography test to detect nicotine metabolites in oral fluids.
Topics: Antibodies; Body Fluids; Chromatography, Affinity; Cotinine; Equipment Design; Humans; Immunoassay; Limit of Detection; Methods; Nicotine; Point-of-Care Systems; Sensitivity and Specificity; Tobacco Smoke Pollution | 2011 |
Pharmacokinetic study of nicotine and its metabolite cotinine to clarify possible association between smoking and voiding dysfunction in rats using UPLC/ESI-MS.
Topics: Animals; Chromatography, Liquid; Cotinine; Female; Humans; Male; Mass Spectrometry; Nicotine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Urination Disorders | 2011 |
Measurement of nicotine, cotinine and trans-3'-hydroxycotinine in meconium by liquid chromatography-tandem mass spectrometry.
Topics: Biomarkers; Chromatography, Liquid; Cotinine; Drug Stability; Female; Humans; Hydroxides; Infant, Newborn; Linear Models; Maternal Exposure; Meconium; Nicotine; Potassium Compounds; Reproducibility of Results; Sensitivity and Specificity; Smoking; Solid Phase Extraction; Tandem Mass Spectrometry | 2011 |
Evaluation of urinary cotinine immunoassay test strips used to assess smoking status.
Topics: Adult; Aged; Chromatography, Liquid; Cotinine; Female; Humans; Immunoassay; Male; Middle Aged; Nicotine; Reagent Strips; Reproducibility of Results; Sensitivity and Specificity; Smoking; Tandem Mass Spectrometry; Tobacco Use Disorder; Young Adult | 2011 |
Simultaneous quantification of nicotine and metabolites in rat brain by liquid chromatography-tandem mass spectrometry.
Topics: Alkaloids; Anabasine; Animals; Biomarkers; Brain Chemistry; Chromatography, Liquid; Cotinine; Linear Models; Male; Nicotine; Pyridines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2011 |
Quantification of nicotine, cotinine, trans-3'-hydroxycotinine and varenicline in human plasma by a sensitive and specific UPLC-tandem mass-spectrometry procedure for a clinical study on smoking cessation.
Topics: Benzazepines; Chromatography, High Pressure Liquid; Cotinine; Drug Stability; Humans; Linear Models; Nicotine; Quinoxalines; Reproducibility of Results; Sensitivity and Specificity; Smoking Cessation; Tandem Mass Spectrometry; Varenicline | 2011 |
Monitoring extracellular K+ flux with a valinomycin-coated silicon nanowire field-effect transistor.
Topics: Animals; Biosensing Techniques; Cattle; Cells, Cultured; Chromaffin Cells; Coated Materials, Biocompatible; Conductometry; Equipment Design; Equipment Failure Analysis; Flow Cytometry; Microfluidic Analytical Techniques; Nanostructures; Nicotine; Potassium; Reproducibility of Results; Sensitivity and Specificity; Silicon; Transistors, Electronic; Valinomycin | 2012 |
Determination of biomarkers of tobacco smoke exposure in oral fluid using solid-phase extraction and gas chromatography-tandem mass spectrometry.
Topics: Adolescent; Biomarkers; Child; Cotinine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Nicotine; Reproducibility of Results; Saliva; Sensitivity and Specificity; Smoking; Solid Phase Extraction; Tobacco Smoke Pollution | 2012 |
Simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine, norcotinine and mecamylamine in human urine by liquid chromatography-tandem mass spectrometry.
Topics: Calibration; Chromatography, Liquid; Cotinine; Humans; Mecamylamine; Nicotine; Sensitivity and Specificity; Smoking; Smoking Cessation; Tandem Mass Spectrometry | 2012 |
Determination of stimulants using gas chromatography/high-resolution time-of-flight mass spectrometry and a soft ionization source.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Codeine; Dopamine Uptake Inhibitors; Equipment Design; GABA Antagonists; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Ions; Methadone; Narcotics; Nicotine; Nikethamide; Norbornanes; Pentylenetetrazole; Phenmetrazine; Sensitivity and Specificity | 2012 |
On-line solid-phase extraction with ultra performance liquid chromatography and tandem mass spectrometry for the detection of nicotine, cotinine and trans-3'-hydroxycotinine in urine to strengthen human biomonitoring and smoking cessation studies.
Topics: Chromatography, Liquid; Cotinine; Environmental Exposure; Humans; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking; Smoking Cessation; Solid Phase Extraction; Tandem Mass Spectrometry; Tobacco Smoke Pollution | 2013 |
Acetylcholine-activated Cl- channel in the Chara tonoplast.
Topics: Acetylcholine; Action Potentials; Chloride Channels; Eukaryota; Membrane Potentials; Nicotine; Patch-Clamp Techniques; Potassium; Reproducibility of Results; Sensitivity and Specificity; Signal Transduction; Vacuoles | 2002 |
Mapping of presynaptic nicotinic acetylcholine receptors using fluorescence imaging of neuritic calcium.
Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Chick Embryo; Fura-2; Ganglia, Sympathetic; Lumbosacral Region; Microscopy, Fluorescence; Motor Neurons; Nicotine; Receptors, Nicotinic; Receptors, Presynaptic; Reproducibility of Results; Sensitivity and Specificity; Synapses; Synaptic Transmission | 2003 |
Biomarkers of tobacco exposure or harm: application to clinical and epidemiological studies. 25-26 October 2001, Minneapolis, Minnesota.
Topics: Alkaloids; Biomarkers; Environmental Exposure; Epidemiologic Studies; Ganglionic Stimulants; Hemoglobins; Humans; Nicotine; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Smoking; Tobacco Smoke Pollution | 2003 |
Measuring nicotine intake in population surveys: comparability of saliva cotinine and plasma cotinine estimates.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chromatography, Gas; Cotinine; Female; Ganglionic Stimulants; Health Surveys; Humans; Male; Middle Aged; Nicotine; Predictive Value of Tests; Regression Analysis; Reproducibility of Results; Saliva; Sensitivity and Specificity; Smoking; Tobacco Smoke Pollution | 2003 |
Acceptability and validity of hair collection from Latino children to assess exposure to environmental tobacco smoke.
Topics: Adult; Aged; Child; Child, Preschool; Cotinine; Environmental Exposure; Female; Ganglionic Stimulants; Hair; Hispanic or Latino; Humans; Indicators and Reagents; Infant; Male; Middle Aged; Nicotine; Parent-Child Relations; Patient Compliance; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Tobacco Smoke Pollution | 2003 |
Measurement of nicotine and cotinine in human milk by high-performance liquid chromatography with ultraviolet absorbance detection.
Topics: Chromatography, High Pressure Liquid; Cotinine; Humans; Milk, Human; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking; Spectrophotometry, Ultraviolet | 2003 |
Determination of nicotine and its metabolites in urine by solid-phase extraction and sample stacking capillary electrophoresis-mass spectrometry.
Topics: Cotinine; Electrophoresis, Capillary; Humans; Mass Spectrometry; Nicotine; Sensitivity and Specificity; Smoking | 2003 |
Determination of nicotine and cotinine in rat plasma by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Cotinine; Mass Spectrometry; Nicotine; Rats; Reproducibility of Results; Sensitivity and Specificity | 2003 |
A simple and reliable method for the determination of nicotine and cotinine in teeth by gas chromatography/mass spectrometry.
Topics: Air Pollutants; Child; Cotinine; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Tooth | 2003 |
Null mutant analysis of responses to nicotine: deletion of beta2 nicotinic acetylcholine receptor subunit but not alpha7 subunit reduces sensitivity to nicotine-induced locomotor depression and hypothermia.
Topics: Animals; Body Temperature; DNA Mutational Analysis; DNA Primers; Gene Deletion; Locomotion; Mice; Mice, Inbred C57BL; Nicotine; Point Mutation; Protein Subunits; Psychomotor Disorders; Receptors, Nicotinic; Sensitivity and Specificity | 2004 |
Determination of nicotine and cotinine in tobacco harvesters' urine by solid-phase extraction and liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Cotinine; Humans; Nicotine; Occupations; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2004 |
Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation.
Topics: Cell Line; Gene Expression; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Sensitivity and Specificity; Smoking Cessation; Structure-Activity Relationship; Time Factors; Up-Regulation | 2004 |
The nicotine dependence syndrome scale: a multidimensional measure of nicotine dependence.
Topics: Adult; Factor Analysis, Statistical; Female; Ganglionic Stimulants; Humans; Male; Middle Aged; Nicotine; Psychometrics; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires; Syndrome; Tobacco Use Disorder | 2004 |
Level of nicotine replacement during a quit-smoking attempt.
Topics: Cotinine; Ganglionic Stimulants; Humans; Nicotine; Predictive Value of Tests; Reproducibility of Results; Saliva; Sensitivity and Specificity; Smoking; Smoking Cessation; Specimen Handling; Time Factors; Tobacco Smoke Pollution; Treatment Outcome | 2004 |
Assessment of smoking status among workers using an improved colorimetric method.
Topics: Colorimetry; Cotinine; Humans; Japan; Nicotine; Sensitivity and Specificity; Smoking | 2004 |
Automated 96-well liquid-liquid back extraction liquid chromatography-tandem mass spectrometry method for the determination of ABT-202 in human plasma.
Topics: Administration, Oral; Automation; Calibration; Chromatography, Liquid; Humans; Mass Spectrometry; Nicotine; Nicotinic Agonists; Pyridines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling | 2004 |
Nicotine and surface of particulates as indicators of exposure to environmental tobacco smoke in public places in Austria.
Topics: Austria; Environmental Monitoring; Feasibility Studies; Female; Filtration; Humans; Male; Nicotine; Sensitivity and Specificity; Tobacco Smoke Pollution | 2004 |
Anxiety sensitivity: association with intensity of retrospectively-rated smoking-related withdrawal symptoms and motivation to quit.
Topics: Adult; Anxiety; Female; Humans; Male; Motivation; Nicotine; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Surveys and Questionnaires | 2004 |
Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry.
Topics: Anabasine; Chromatography, Liquid; Humans; Mass Spectrometry; Nicotine; Sensitivity and Specificity; Substance Abuse Detection | 2004 |
The AMA proposal to mandate nicotine reduction in cigarettes: a simulation of the population health impacts.
Topics: American Medical Association; Health Status Indicators; Humans; Nicotiana; Nicotine; Public Policy; Quality-Adjusted Life Years; Sensitivity and Specificity; United States | 2005 |
Simultaneous determination of nicotine, cotinine, norcotinine, and trans-3'-hydroxycotinine in human oral fluid using solid phase extraction and gas chromatography-mass spectrometry.
Topics: Cotinine; Female; Gas Chromatography-Mass Spectrometry; Humans; Nicotine; Pregnancy; Reproducibility of Results; Saliva; Sensitivity and Specificity; Smoking | 2005 |
Nicotine exposure, mimicked smoking, directly and indirectly enhanced protein kinase C activity in isolated canine basilar artery, resulting in enhancement of arterial contraction.
Topics: Animals; Basilar Artery; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nicotine; Nitric Oxide; Protein Kinase C; Sensitivity and Specificity; Smoking; Uridine Triphosphate; Vasoconstriction | 2005 |
Validation and application of a method for the determination of nicotine and five major metabolites in smokers' urine by solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Topics: Chemical Fractionation; Chromatography, Liquid; Circadian Rhythm; Creatinine; Freezing; Humans; Mass Spectrometry; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking; Smoking Cessation | 2005 |
[Veracity of smokers' reports of abstinence at smoking cessation clinics].
Topics: Adult; Breath Tests; Bupropion; Carbon Monoxide; Data Interpretation, Statistical; Dopamine Uptake Inhibitors; Female; Humans; Longitudinal Studies; Male; Middle Aged; Motivation; Nicotine; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Smoking Cessation; Spain; Time Factors | 2005 |
A rapid LC-MS-MS method for the determination of nicotine and cotinine in serum and saliva samples from smokers: validation and comparison with a radioimmunoassay method.
Topics: Animals; Chromatography, Liquid; Cotinine; Humans; Mass Spectrometry; Nicotine; Quality Control; Radioimmunoassay; Rats; Reproducibility of Results; Saliva; Sensitivity and Specificity; Smoking | 2005 |
Stimulation of defecation: effects of coffee use and nicotine on rectal tone and visceral sensitivity.
Topics: Adult; Analysis of Variance; Coffee; Cohort Studies; Defecation; Female; Gastrointestinal Motility; Humans; Male; Manometry; Nicotine; Rectum; Reference Values; Risk Assessment; Sensitivity and Specificity | 2005 |
Simultaneous determination of nicotine and its metabolite, cotinine, in rat blood and brain tissue using microdialysis coupled with liquid chromatography: pharmacokinetic application.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cotinine; Microdialysis; Nicotine; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2005 |
Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography-electrospray tandem mass spectrometric (HILIC-ESI/MS/MS) bioanalysis of basic compounds.
Topics: Acetic Acid; Chromatography, Liquid; Cotinine; Ethionamide; Fluconazole; Humans; Isoniazid; Nicotine; Piperazines; Propionates; Purines; Pyrazinamide; Sensitivity and Specificity; Sildenafil Citrate; Spectrometry, Mass, Electrospray Ionization; Sulfones; Trifluoroacetic Acid | 2005 |
Analysis of nicotinoid insecticides residues in honey by solid matrix partition clean-up and liquid chromatography-electrospray mass spectrometry.
Topics: Honey; Nicotine; Pesticide Residues; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Chronic pancreatic inflammation induced by environmental tobacco smoke inhalation in rats.
Topics: Animals; Biopsy, Needle; Cotinine; Disease Models, Animal; Female; Immunohistochemistry; Nicotine; Pancreatic Function Tests; Pancreatitis-Associated Proteins; Pancreatitis, Chronic; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Tobacco Smoke Pollution | 2006 |
A quantitative high-throughput trapping assay as a measurement of potential for bioactivation.
Topics: Autoanalysis; Biotransformation; Carbon Radioisotopes; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Humans; Microsomes, Liver; Nicotine; Pharmaceutical Preparations; Potassium Cyanide; Scintillation Counting; Sensitivity and Specificity | 2006 |
Histological changes in intervertebral discs after smoking and cessation: experimental study using a rat passive smoking model.
Topics: Animals; Animals, Newborn; Biopsy, Needle; Disease Models, Animal; Immunohistochemistry; Intervertebral Disc Displacement; Male; Nicotine; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Assessment; Sensitivity and Specificity; Smoking; Smoking Cessation | 2006 |
A validated method for the determination of nicotine, cotinine, trans-3'-hydroxycotinine, and norcotinine in human plasma using solid-phase extraction and liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.
Topics: Atmospheric Pressure; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cotinine; Humans; Nicotine; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization | 2006 |
CYP2A6 genotype, phenotype, and the use of nicotine metabolites as biomarkers during ad libitum smoking.
Topics: Adolescent; Adult; Aged; Alleles; Analysis of Variance; Aryl Hydrocarbon Hydroxylases; Biomarkers; Breath Tests; Canada; Carbon Monoxide; Chromatography, High Pressure Liquid; Cotinine; Cytochrome P-450 CYP2A6; Female; Genetic Variation; Genotype; Humans; Male; Middle Aged; Mixed Function Oxygenases; Nicotine; Nicotinic Agonists; Phenotype; Polymerase Chain Reaction; Sensitivity and Specificity; Smoking; White People | 2006 |
Mass spectrometric quantitation of nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human toenails.
Topics: Cotinine; Gas Chromatography-Mass Spectrometry; Humans; Nails; Nicotine; Nitrosamines; Sensitivity and Specificity | 2006 |
[Determination of nicotine and cotinine in human biological materials and their significance in toxicological studies].
Topics: Aged; Chromatography, High Pressure Liquid; Clinical Chemistry Tests; Cotinine; Diagnosis, Differential; Female; Forensic Toxicology; Hair; Humans; Inhalation Exposure; Male; Middle Aged; Nicotine; Saliva; Sensitivity and Specificity; Smoking; Specimen Handling; Tobacco Smoke Pollution; Tobacco Use Disorder | 2006 |
Nicotine dependence among African American light smokers: a comparison of three scales.
Topics: Adult; Black or African American; Chewing Gum; Counseling; Factor Analysis, Statistical; Female; Humans; Male; Middle Aged; Nicotine; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Smoking; Smoking Cessation; Surveys and Questionnaires; Tobacco Use Disorder | 2007 |
Miniaturized sample preparation needle: a versatile design for the rapid analysis of smoking-related compounds in hair and air samples.
Topics: Acetaldehyde; Breath Tests; Chromatography, Gas; Environmental Exposure; Equipment Design; Formaldehyde; Hair; Humans; Miniaturization; Needles; Nicotine; Organic Chemicals; Reproducibility of Results; Sensitivity and Specificity; Smoking; Tobacco Smoke Pollution; Volatilization | 2007 |
Sensitivity and specificity of a reagent-impregnated test strip in identifying smokeless tobacco users.
Topics: Adult; Biomarkers; Chromatography, High Pressure Liquid; Cotinine; Female; Humans; Male; Nicotine; Psychometrics; Reagent Strips; Reproducibility of Results; Saliva; Sensitivity and Specificity; Substance Abuse Detection; Surveys and Questionnaires; Tobacco Smoke Pollution; Tobacco Use Disorder; Tobacco, Smokeless | 2007 |
Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes.
Topics: Acetylcholine; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Benzylidene Compounds; Bridged Bicyclo Compounds; Calcium; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genistein; Humans; Indoles; Isoxazoles; Kidney; Microinjections; Naphthalenes; Nicotine; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Phenylurea Compounds; Protein-Tyrosine Kinases; Pyridines; Quinolines; Receptors, Cholinergic; Receptors, Nicotinic; Sensitivity and Specificity; Sulfonamides; Xenopus laevis | 2007 |
Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine.
Topics: Adult; Aged; Biomarkers; Cotinine; Endpoint Determination; Environmental Exposure; Female; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Inhalation Exposure; Longitudinal Studies; Male; Middle Aged; Nails; Nicotine; Nitrosamines; Sensitivity and Specificity; Smoking | 2007 |
Liquid chromatography/electrospray ionization tandem mass spectrometry assay for determination of nicotine and metabolites, caffeine and arecoline in breast milk.
Topics: Arecoline; Caffeine; Chromatography, High Pressure Liquid; Humans; Milk, Human; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2007 |
Analysis of [3',3'-d(2)]-nicotine and [3',3'-d(2)]-cotinine by capillary liquid chromatography-electrospray tandem mass spectrometry.
Topics: Administration, Oral; Biomarkers; Calibration; Capillary Electrochromatography; Chromatography, High Pressure Liquid; Cotinine; Deuterium; Humans; Injections, Intravenous; Molecular Structure; Nicotine; Radioactive Tracers; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Smoking; Smoking Cessation; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2007 |
Physician beliefs regarding effectiveness of tobacco dependence treatments: results from the NJ Health Care Provider Tobacco Survey.
Topics: Adult; Attitude of Health Personnel; Behavior Therapy; Bupropion; Female; Humans; Male; Middle Aged; New Jersey; Nicotine; Nicotinic Agonists; Patient Compliance; Practice Patterns, Physicians'; Risk Assessment; Sensitivity and Specificity; Smoking Cessation; Tobacco Use Disorder; Treatment Outcome | 2007 |
Validation of self-reported smoking status using saliva cotinine: a rapid semiquantitative dipstick method.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chromatography, Liquid; Cotinine; Data Collection; Humans; Immunoassay; Middle Aged; Nicotine; Saliva; Sensitivity and Specificity; Smoking | 2007 |
[Detecting nicotine and its metabolite cotinine in human hair with capillary gas chromatography].
Topics: Cotinine; Flame Ionization; Hair; Humans; Limit of Detection; Nicotine; Sensitivity and Specificity | 2008 |
Development of behavioral sensitization to cocaine: influence of kappa opioid receptor agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Cocaine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Locomotion; Male; Nicotine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sensitivity and Specificity; Sodium Chloride | 1995 |
Cardiovascular and behavioral responses to nicotinic agents administered intrathecally.
Topics: Aconitine; Alkaloids; Animals; Atropine; Azocines; Behavior, Animal; Blood Pressure; Bungarotoxins; Cardiovascular System; Dihydro-beta-Erythroidine; Ganglionic Stimulants; Heart Rate; Injections, Spinal; Lobeline; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Nociceptors; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sensitivity and Specificity; Spinal Cord; Trimethaphan | 1994 |
Ligand specificity of nicotinic acetylcholine receptors in rat spinal cord: studies with nicotine and cytisine.
Topics: Alkaloids; Animals; Azocines; Binding Sites; Binding, Competitive; Ganglionic Stimulants; In Vitro Techniques; Kinetics; Ligands; Male; Membranes; Nicotine; Nicotinic Antagonists; Quinolizines; Rats; Receptors, Nicotinic; Sensitivity and Specificity; Spinal Cord; Tritium | 1994 |
Simultaneous determination of nicotine and cotinine in various human tissues using capillary gas chromatography/mass spectrometry.
Topics: Adipose Tissue; Adult; Autopsy; Brain Chemistry; Calibration; Cotinine; Gas Chromatography-Mass Spectrometry; Humans; Kidney; Liver; Lung; Muscles; Nicotine; Sensitivity and Specificity; Spleen; Tissue Distribution | 1994 |
Pharmacological sensitivity of the articular capsule of the primary spines of Eucidaris tribuloides.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Drug Interactions; In Vitro Techniques; Ligaments, Articular; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Octopamine; Parasympathomimetics; Phenethylamines; Receptors, Muscarinic; Receptors, Nicotinic; Sea Urchins; Sensitivity and Specificity; Tubocurarine; Tyramine | 1993 |
Comparison of a mechanized version of the 'König' reaction and a fluorescence polarization immunoassay for the determination of nicotine metabolites in urine.
Topics: Autoanalysis; Cotinine; Fluorescence Polarization Immunoassay; Humans; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Smoking | 1993 |
Effects on thyroid hormone metabolism and depletion of lung vitamin A in rats by airborne particulate matter.
Topics: Aerosols; Air Pollutants; Animals; Chemical Fractionation; Chlorophenols; Female; Lung; Nicotine; Nitro Compounds; Particle Size; Pentachlorophenol; Polycyclic Compounds; Prealbumin; Rats; Rats, Wistar; Sensitivity and Specificity; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Vitamin A; Vitamin A Deficiency | 1993 |
Differential desensitization properties of rat neuronal nicotinic acetylcholine receptor subunit combinations expressed in Xenopus laevis oocytes.
Topics: Acetylcholine; Animals; Drug Tolerance; Egtazic Acid; Electrophysiology; HEPES; Isotonic Solutions; Neurons; Nicotine; Oocytes; Rats; Receptors, Nicotinic; Ringer's Solution; Sensitivity and Specificity; Up-Regulation; Xenopus laevis | 1995 |
The benefits and risks of over-the-counter availability of nicotine polacrilex ("nicotine gum").
Topics: Adolescent; Adult; Aged; Chewing Gum; Drug and Narcotic Control; Drug Prescriptions; Female; Humans; Male; Markov Chains; Middle Aged; Models, Theoretical; Nicotine; Nonprescription Drugs; Polymethacrylic Acids; Polyvinyls; Risk Assessment; Sensitivity and Specificity; Smoking; Smoking Cessation; Tobacco Use Cessation Devices; United States | 1996 |
Pharmacoeconomic analysis of smoking-cessation interventions.
Topics: Behavior Therapy; Cost-Benefit Analysis; Decision Trees; Humans; Nicotine; Nicotinic Agonists; Sensitivity and Specificity; Smoking; Smoking Cessation; Treatment Outcome | 1996 |
Determination of nicotine and cotinine in human plasma by liquid chromatography-tandem mass spectrometry with atmospheric-pressure chemical ionization interface.
Topics: Chromatography, Liquid; Cotinine; Humans; Mass Spectrometry; Nicotine; Reproducibility of Results; Sensitivity and Specificity | 1996 |
Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Electrochemistry; Electrodes, Implanted; Injections, Intravenous; Injections, Subcutaneous; Male; Microelectrodes; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 1997 |
Simple and sensitive method for determination of nicotine in plasma by gas chromatography.
Topics: Chromatography, Gas; Humans; Nicotine; Reproducibility of Results; Sensitivity and Specificity | 1997 |
Functional deactivation of the major neuronal nicotinic receptor caused by nicotine and a protein kinase C-dependent mechanism.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Line; Enzyme Inhibitors; Humans; Kinetics; Neurons; Nicotine; Nicotinic Agonists; Phosphoric Monoester Hydrolases; Protein Conformation; Protein Kinase C; Pyridines; Receptors, Nicotinic; Sensitivity and Specificity; Transfection; Up-Regulation | 1997 |
Assessment of simple colorimetric procedures to determine smoking status of diabetic subjects.
Topics: Colorimetry; Creatinine; Diabetes Mellitus; Humans; Nicotine; Regression Analysis; Sensitivity and Specificity; Smoking; Thiobarbiturates | 1998 |
Application of high-performance capillary electrophoresis to the quantitative analysis of nicotine and profiling of other alkaloids in ATF-regulated tobacco products.
Topics: Alkaloids; Electrophoresis, Capillary; Government Agencies; Hydrogen-Ion Concentration; Nicotiana; Nicotine; Plants, Toxic; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1998 |
Nicotine monitoring in sweat with a sweat patch.
Topics: Adult; Drug Monitoring; Environmental Exposure; Gas Chromatography-Mass Spectrometry; Humans; Middle Aged; Nicotine; Pilot Projects; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Skin; Smoking; Sweat; Tobacco Smoke Pollution | 1998 |
Rapid method for the simultaneous measurement of nicotine and cotinine in urine and serum by gas chromatography-mass spectrometry.
Topics: Cotinine; Gas Chromatography-Mass Spectrometry; Humans; Nicotine; Sensitivity and Specificity | 1998 |
Rapid and sensitive high-performance liquid chromatographic determination of nicotine and cotinine in nonsmoker human and rat urines.
Topics: Adolescent; Adult; Animals; Child; Chromatography, High Pressure Liquid; Cotinine; Evaluation Studies as Topic; Female; Humans; Male; Nicotine; Rats; Sensitivity and Specificity; Smoking; Time Factors; Tobacco Smoke Pollution | 1998 |
Inhibitory effect of nicotine and its metabolites on tolbutamide hydroxylation in rat liver microsomes.
Topics: Animals; Chromatography, High Pressure Liquid; Cotinine; Fluorescence; Hydroxylation; Hypoglycemic Agents; Microsomes, Liver; Molecular Structure; Nicotine; Rats; Sensitivity and Specificity; Smoking; Tolbutamide | 1998 |
Human and rodent bronchial epithelial cells express functional nicotinic acetylcholine receptors.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Cell Adhesion; Cell Size; Cells, Cultured; Cholinergic Antagonists; Epithelial Cells; Fluorescent Antibody Technique; Humans; In Situ Hybridization; Membrane Potentials; Neurons; Nicotine; Nicotinic Agonists; Pyridines; Rabbits; Rats; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Species Specificity; Trachea; Tritium | 1998 |
Prescription of transdermal nicotine patches for smoking cessation in general practice: evaluation of cost-effectiveness.
Topics: Administration, Cutaneous; Adult; Aged; Cost-Benefit Analysis; Counseling; Drug Prescriptions; Family Practice; Humans; Middle Aged; Nicotine; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Smoking Cessation; State Medicine; United Kingdom | 1999 |
The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cotinine; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; DNA Primers; Exons; Female; Gene Frequency; Genetic Testing; Homozygote; Humans; Japan; Male; Mixed Function Oxygenases; Nicotine; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Sensitivity and Specificity; Sequence Deletion; Smoking | 1999 |
Antagonist activities of mecamylamine and nicotine show reciprocal dependence on beta subunit sequence in the second transmembrane domain.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Female; Mecamylamine; Membrane Proteins; Mice; Molecular Sequence Data; Muscles; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Point Mutation; Rats; Receptors, Nicotinic; Sensitivity and Specificity; Sequence Homology, Amino Acid; Xenopus | 1999 |
Initial exposure to nicotine in college-age women smokers and never-smokers: a replication and extension.
Topics: Adult; Attitude; Body Image; Female; Humans; Nicotine; Sensitivity and Specificity; Smoking; Surveys and Questionnaires; Universities | 1999 |
Periadolescent nicotine exposure reduces cocaine reward in adult mice.
Topics: Age Factors; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Locomotion; Male; Mice; Mice, Inbred C57BL; Nicotine; Reinforcement, Psychology; Reward; Self Administration; Sensitivity and Specificity; Weight Gain | 1999 |
How accurate is in-patient smoking status data collected by hospital admissions staff?
Topics: Adolescent; Adult; Data Collection; Diagnostic Tests, Routine; Female; Health Personnel; Humans; Male; Middle Aged; New South Wales; Nicotine; Patient Participation; Reproducibility of Results; Sensitivity and Specificity; Smoking; Statistics as Topic; Urine | 1999 |
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
Topics: Antidepressive Agents, Tricyclic; Cannabinoids; Chlormethiazole; Diphenhydramine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Lidocaine; Methadone; Nicotine; Poisoning; Sensitivity and Specificity; Solvents; Substance Abuse Detection; Tramadol | 2000 |
Use of environmental tobacco smoke constituents as markers for exposure.
Topics: Age Factors; Air Pollutants; Air Pollutants, Occupational; Alkaloids; Biomarkers; Cotinine; Environmental Exposure; Fluorescence; Forecasting; Humans; Linear Models; Nicotine; Nicotinic Agonists; Occupational Exposure; Pyridines; Regression Analysis; Saliva; Scopoletin; Sensitivity and Specificity; Smoking; Terpenes; Time Factors; Tobacco Smoke Pollution; Ultraviolet Rays | 1999 |
Measuring infant exposure to environmental tobacco smoke.
Topics: Acute Disease; Adult; Chronic Disease; Cotinine; Environmental Exposure; Environmental Monitoring; Female; Humans; Infant; Infant Welfare; Infant, Newborn; Longitudinal Studies; Mothers; Nicotine; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Surveys and Questionnaires; Tobacco Smoke Pollution | 1999 |
Improved highly sensitive method for determination of nicotine and cotinine in human plasma by high-performance liquid chromatography.
Topics: Calibration; Chromatography, High Pressure Liquid; Cotinine; Humans; Nicotine; Reproducibility of Results; Sensitivity and Specificity | 2000 |
Is it the nicotine or the tobacco?
Topics: Child; Disease Outbreaks; Global Health; Humans; Nicotiana; Nicotine; Plants, Toxic; Prevalence; Risk Assessment; Sensitivity and Specificity; Smoking; Tobacco Use Disorder | 2000 |
Taking the nicotine out of cigarettes--why it is a bad idea.
Topics: Humans; Nicotine; Primary Prevention; Sensitivity and Specificity; Smoking Cessation; Tobacco Use Disorder; World Health Organization | 2000 |
Near-patient test for nicotine and its metabolites in saliva to assess smoking habit.
Topics: Adult; Colorimetry; Cotinine; Female; Humans; Male; Nicotine; Point-of-Care Systems; Radioimmunoassay; Saliva; Sensitivity and Specificity; Smoking; Smoking Cessation; Statistics as Topic | 2000 |
Simple colorimetric test to quantify exposure to environmental tobacco smoke: occupational health study.
Topics: Adult; Environmental Exposure; Female; Humans; Male; Nicotine; Occupational Exposure; Risk Assessment; Sensitivity and Specificity; Tobacco Smoke Pollution | 2000 |
Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats.
Topics: Animals; Colitis; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enteritis; Intestinal Mucosa; Iodoacetamide; Jejunal Diseases; Male; Nicotine; Nitric Oxide Synthase; Peroxidase; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric | 2001 |
Measurement of nicotine in hair by reversed-phase high-performance liquid chromatography with electrochemical detection.
Topics: Child, Preschool; Chromatography, High Pressure Liquid; Electrochemistry; Environmental Exposure; Hair; Humans; Infant; Nicotine; Reproducibility of Results; Sensitivity and Specificity; Tobacco Smoke Pollution | 2001 |
Novel liquid chromatographic-tandem mass spectrometric methods using silica columns and aqueous-organic mobile phases for quantitative analysis of polar ionic analytes in biological fluids.
Topics: Albuterol; Body Fluids; Chromatography, Liquid; Cotinine; Drug Stability; Humans; Mass Spectrometry; Nicotine; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Silicon Dioxide; Solvents; Water | 2001 |
A study of a new TSM bio-mimetic sensor using a molecularly imprinted polymer coating and its application for the determination of nicotine in human serum and urine.
Topics: Biosensing Techniques; Humans; Molecular Mimicry; Nicotine; Polymers; Reproducibility of Results; Sensitivity and Specificity | 2001 |
Determination of tobacco alkaloids in single plant cells by capillary electrophoresis.
Topics: Electrophoresis, Capillary; Nicotiana; Nicotine; Plants, Toxic; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2001 |
Should we recommend nicotine replacement therapy?
Topics: Adult; Behavior, Addictive; Evidence-Based Medicine; Female; Humans; Nicotine; Respiratory Tract Infections; Risk Assessment; Sensitivity and Specificity; Smoking; Smoking Cessation; Smoking Prevention | 2001 |
Information from your family doctor. Using the nicotine patch, nicotine gum, nicotine nasal spray or nicotine inhaler.
Topics: Administration, Inhalation; Administration, Intranasal; Delayed-Action Preparations; Drug Delivery Systems; Family Practice; Female; Health Education; Humans; Male; Nicotine; Sensitivity and Specificity; Smoking Cessation; Smoking Prevention; Substance-Related Disorders | 2001 |
Quantification of nicotine, chlorpyrifos and their metabolites in rat plasma and urine using high-performance liquid chromatography.
Topics: Animals; Chlorpyrifos; Chromatography, High Pressure Liquid; Nicotine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2001 |
High-performance liquid chromatographic determination of pyridostigmine bromide, nicotine, and their metabolites in rat plasma and urine.
Topics: Animals; Chromatography, High Pressure Liquid; Nicotine; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2001 |
Measurement of self reported active exposure to cigarette smoke.
Topics: Adolescent; Adult; Aged; Biomarkers; Cotinine; Female; Humans; Male; Middle Aged; Multivariate Analysis; Nicotine; Saliva; Sensitivity and Specificity; Smoking; Surveys and Questionnaires | 2001 |
Receptor-mediated action of nicotine in human skin.
Topics: Female; Humans; Male; Nicotine; Receptors, Cholinergic; Sensitivity and Specificity; Skin; Skin Diseases | 2001 |
The use of nicotine in dermatology revisited.
Topics: Humans; Nicotine; Pemphigus; Pyoderma Gangrenosum; Sensitivity and Specificity; Skin Diseases; Treatment Outcome | 2001 |
Is the hair nicotine level a more accurate biomarker of environmental tobacco smoke exposure than urine cotinine?
Topics: Biomarkers; Child, Preschool; Cotinine; Cross-Sectional Studies; Ganglionic Stimulants; Hair; Humans; Infant; Nicotine; Sensitivity and Specificity; Smoking; Surveys and Questionnaires; Tobacco Smoke Pollution | 2002 |
Sensitive and simple method for the determination of nicotine and cotinine in human urine, plasma and saliva by gas chromatography-mass spectrometry.
Topics: Cotinine; Gas Chromatography-Mass Spectrometry; Humans; Nicotine; Reproducibility of Results; Saliva; Sensitivity and Specificity | 2002 |
Assessment of the automated colorimetric and the high-performance liquid chromatographic methods for nicotine intake by urine samples of smokers' smoking low- and medium-yield cigarettes.
Topics: Acetanilides; Adult; Barbiturates; Chromatography, High Pressure Liquid; Colorimetry; Cotinine; Female; Humans; Male; Nicotine; Sensitivity and Specificity; Smoking | 1991 |