Page last updated: 2024-08-07 17:14:58
Substance-K receptor
A protein that is a translation product of the TACR2 gene in guinea pig. [PRO:DNx, UniProtKB:Q64077]
Synonyms
SKR;
NK-2 receptor;
NK-2R;
Neurokinin A receptor;
Tachykinin receptor 2
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (26)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| catechin | Cavia porcellus (domestic guinea pig) | IC50 | 100.0000 | 1 | 1 |
| hesperidin | Cavia porcellus (domestic guinea pig) | IC50 | 100.0000 | 1 | 1 |
| (+)-epicatechin | Cavia porcellus (domestic guinea pig) | IC50 | 100.0000 | 1 | 1 |
| scutellarin | Cavia porcellus (domestic guinea pig) | IC50 | 50.6000 | 1 | 1 |
| naringenin | Cavia porcellus (domestic guinea pig) | IC50 | 100.0000 | 1 | 1 |
| gs 4071 | Cavia porcellus (domestic guinea pig) | IC50 | 0.0150 | 1 | 1 |
| likviriton | Cavia porcellus (domestic guinea pig) | IC50 | 100.0000 | 1 | 1 |
| quercetin | Cavia porcellus (domestic guinea pig) | IC50 | 58.4000 | 1 | 1 |
| formononetin | Cavia porcellus (domestic guinea pig) | IC50 | 100.0000 | 1 | 1 |
| vitexin | Cavia porcellus (domestic guinea pig) | IC50 | 46.5000 | 1 | 1 |
| apigenin | Cavia porcellus (domestic guinea pig) | IC50 | 31.6000 | 1 | 1 |
| luteolin | Cavia porcellus (domestic guinea pig) | IC50 | 33.7000 | 1 | 1 |
| luteolin-7-glucoside | Cavia porcellus (domestic guinea pig) | IC50 | 47.4000 | 1 | 1 |
| rutin | Cavia porcellus (domestic guinea pig) | IC50 | 52.2000 | 1 | 1 |
| kaempferol | Cavia porcellus (domestic guinea pig) | IC50 | 58.6000 | 1 | 1 |
| genistein | Cavia porcellus (domestic guinea pig) | IC50 | 77.1000 | 1 | 1 |
| sulfuretin | Cavia porcellus (domestic guinea pig) | IC50 | 29.6000 | 1 | 1 |
| chrysin | Cavia porcellus (domestic guinea pig) | IC50 | 45.7000 | 1 | 1 |
| hispidulin | Cavia porcellus (domestic guinea pig) | IC50 | 46.3000 | 1 | 1 |
| myricetin | Cavia porcellus (domestic guinea pig) | IC50 | 82.6000 | 1 | 1 |
| daidzein | Cavia porcellus (domestic guinea pig) | IC50 | 37.1000 | 1 | 1 |
| neurokinin a | Cavia porcellus (domestic guinea pig) | Ki | 3.7000 | 1 | 1 |
| kaempferol-7-methyl ether | Cavia porcellus (domestic guinea pig) | IC50 | 51.5000 | 1 | 1 |
| sophoricoside | Cavia porcellus (domestic guinea pig) | IC50 | 100.0000 | 1 | 1 |
| suvorexant | Cavia porcellus (domestic guinea pig) | Ki | 0.0004 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| dnk 333 | Cavia porcellus (domestic guinea pig) | Kd | 0.0537 | 1 | 1 |