aristolochic acid i has been researched along with Sensitivity and Specificity in 15 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aristolochic acid I (AAI) was regarded as the major toxic component of aristolochic acid (AA)." | 1.51 | The Disturbance of Hepatic and Serous Lipids in Aristolochic Acid Ι Induced Rats for Hepatotoxicity Using Lipidomics Approach. ( Bian, B; Si, N; Wang, H; Wei, X; Yang, J; Yang, Y; Zhao, H; Zhou, J; Zhou, Y, 2019) |
| "Aristolochic acid II was the major component for Aristolochia contorta and its range was <1-115 ppm." | 1.31 | High-performance liquid chromatographic determination for aristolochic acid in medicinal plants and slimming products. ( Deng, JF; Hwang, DF; Lee, TY; Wu, ML, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 10 (66.67) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X | 1 |
| Huang, T | 1 |
| Huang, Z | 1 |
| Han, Q | 1 |
| Zhou, J | 1 |
| Yang, Y | 1 |
| Wang, H | 1 |
| Bian, B | 1 |
| Yang, J | 1 |
| Wei, X | 1 |
| Zhou, Y | 1 |
| Si, N | 1 |
| Zhao, H | 1 |
| Cai, ZW | 1 |
| Chan, AY | 1 |
| Zhao, ZZ | 1 |
| Xue, Y | 1 |
| Tong, XH | 1 |
| Wang, F | 1 |
| Zhao, WG | 1 |
| Fu, X | 1 |
| Liu, Y | 1 |
| Li, W | 1 |
| Pang, N | 1 |
| Nie, H | 1 |
| Liu, H | 1 |
| Cai, Z | 2 |
| Guo, L | 1 |
| Wu, H | 1 |
| Yue, H | 1 |
| Lin, S | 1 |
| Lai, Y | 1 |
| Sun, Z | 1 |
| Liu, L | 1 |
| Zheng, X | 1 |
| Fan, C | 1 |
| Wang, Q | 1 |
| Li, G | 1 |
| Hsieh, SC | 1 |
| Huang, MF | 1 |
| Lin, BS | 1 |
| Chang, HT | 1 |
| Yu, FY | 1 |
| Lin, YH | 1 |
| Su, CC | 1 |
| Kim, MS | 1 |
| Hahn, Y | 1 |
| Wei, F | 1 |
| Feng, YQ | 1 |
| Broschard, TH | 1 |
| Wiessler, M | 1 |
| von der Lieth, CW | 1 |
| Schmeiser, HH | 1 |
| Ong, ES | 1 |
| Woo, SO | 1 |
| Yong, YL | 1 |
| Lee, TY | 1 |
| Wu, ML | 1 |
| Deng, JF | 1 |
| Hwang, DF | 1 |
| Kite, GC | 1 |
| Yule, MA | 1 |
| Leon, C | 1 |
| Simmonds, MS | 1 |
15 other studies available for aristolochic acid i and Sensitivity and Specificity
| Article | Year |
|---|---|
Development of an immunochromatographic test strip for the rapid detection of aristolochic acid A in herbal medicinal materials.
Topics: Animals; Aristolochic Acids; Gold; Gold Colloid; Metal Nanoparticles; Mice; Sensitivity and Specific | 2022 |
The Disturbance of Hepatic and Serous Lipids in Aristolochic Acid Ι Induced Rats for Hepatotoxicity Using Lipidomics Approach.
Topics: Animals; Aristolochic Acids; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Administration | 2019 |
Rapid and specific determination of DNA adducts for clinical diagnosis of poisoning and disease associated with aristolochic acid.
Topics: Aristolochic Acids; Biomarkers; Chromatography, Liquid; DNA Adducts; Humans; In Vitro Techniques; Ma | 2013 |
[Analysis of aristolochic acid A from the aerial and underground parts of Asarum by UPLC-UV].
Topics: Aristolochic Acids; Asarum; Chromatography, High Pressure Liquid; Drug Stability; Plant Components, | 2008 |
Analysis of aristolochic acids by CE-MS with carboxymethyl chitosan-coated capillary.
Topics: Aristolochic Acids; Chitosan; Electrophoresis, Capillary; Humans; Mass Spectrometry; Sensitivity and | 2009 |
A novel and specific method for the determination of aristolochic acid-derived DNA adducts in exfoliated urothelial cells by using ultra performance liquid chromatography-triple quadrupole mass spectrometry.
Topics: Animals; Aristolochic Acids; Chromatography, High Pressure Liquid; Deoxyadenosines; DNA Adducts; Lin | 2011 |
An easy and rapid method to determine aristolochic acids I and II with high sensitivity.
Topics: Aristolochia; Aristolochic Acids; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes | 2004 |
Determination of aristolochic acid in Chinese herbal medicine by capillary electrophoresis with laser-induced fluorescence detection.
Topics: Aristolochic Acids; Dietary Supplements; Drugs, Chinese Herbal; Electrophoresis, Capillary; Lasers; | 2006 |
A sensitive enzyme-linked immunosorbent assay for detecting carcinogenic aristolochic acid in herbal remedies.
Topics: Animals; Antibodies; Aristolochic Acids; Carcinogens; Drug Contamination; Enzyme-Linked Immunosorben | 2006 |
Electrochemical behavior and square wave voltammetric determination of aristolochic acid-I.
Topics: Aristolochia; Aristolochic Acids; Calibration; Electrochemistry; Electrodes; Fruit; Molecular Struct | 2007 |
Rapid determination of aristolochic acid I and II in medicinal plants with high sensitivity by cucurbit[7]uril-modifier capillary zone electrophoresis.
Topics: Aristolochic Acids; Bridged-Ring Compounds; Electrophoresis, Capillary; Hydrogen-Ion Concentration; | 2008 |
Translesional synthesis on DNA templates containing site-specifically placed deoxyadenosine and deoxyguanosine adducts formed by the plant carcinogen aristolochic acid.
Topics: Aristolochic Acids; Base Sequence; Binding Sites; Carcinogens; Deoxyadenosines; Deoxyguanosine; DNA; | 1994 |
Pressurized liquid extraction of berberine and aristolochic acids in medicinal plants.
Topics: Aristolochic Acids; Berberine; Chromatography, High Pressure Liquid; Phenanthrenes; Plants, Medicina | 2000 |
High-performance liquid chromatographic determination for aristolochic acid in medicinal plants and slimming products.
Topics: Appetite Depressants; Aristolochic Acids; Chromatography, High Pressure Liquid; Hydrogen-Ion Concent | 2002 |
Detecting aristolochic acids in herbal remedies by liquid chromatography/serial mass spectrometry.
Topics: Aristolochia; Aristolochic Acids; Carcinogens; Chromatography, Liquid; Herbal Medicine; Mass Spectro | 2002 |