agaritine profile

ID Source	ID
PubMed CID	439517
CHEBI ID	15336
SCHEMBL ID	2678851
MeSH ID	M0065102

Synonym
2-amino-5-{2-[4-(hydroxymethyl)phenyl]hydrazino}-5-oxopentanoic acid
brn 0757731
ccris 5459
nci-c08899
beta-n-(alpha-l-glutamyl)-4-hydroxymethylphenylhydrazine
hsdb 4202
l-glutamic acid, 5-(2-(alpha-hydroxy-para-tolyl)hydrazide)
beta-n-(gamma-l(+)glutamyl)4-hydroxymethylphenylhydrazine
glutamic acid, 5-(2-(alpha-hydroxy-p-tolyl)hydrazide), l-
agaritine ,
C01550
2757-90-6
l-glutamic acid, 5-(2-(4-(hydroxymethyl)phenyl)hydrazide)
(2s)-2-amino-5-{2-[4-(hydroxymethyl)phenyl]hydrazino}-5-oxopentanoic acid
2-[4-(hydroxymethyl)phenyl]-l-glutamohydrazide
beta-n-[gamma-l(+)-glutamyl]-4-hydroxymethylphenylhydrazine
CHEBI:15336
(2s)-2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazinyl]-5-oxopentanoic acid
unii-ux8y7qvp8m
ux8y7qvp8m ,
agaritine [mi]
agaritine [iarc]
SCHEMBL2678851
DTXSID9020661
l-glutamic acid, 5-[2-[4-(hydroxymethyl)phenyl]hydrazide]
Q2315302
AKOS040750187

Class	Description
carbohydrazide	A hydrazide consisting of hydrazine carrying one or more carboacyl groups.
L-glutamic acid derivative	A proteinogenic amino acid derivative resulting from reaction of L-glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen of L-glutamic acid by a heteroatom.
benzyl alcohols	Compounds containing a phenylmethanol skeleton.
non-proteinogenic L-alpha-amino acid	Any L-alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.
amino acid zwitterion	The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	10 (27.03)	18.7374
1990's	10 (27.03)	18.2507
2000's	12 (32.43)	29.6817
2010's	5 (13.51)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (5.26%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	36 (94.74%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
methanol Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.	6.97	1	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite
glutamine Glutamine: A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.. L-glutamine : An optically active form of glutamine having L-configuration.. glutamine : An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4.	2.39	2	amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
phenylhydrazine [no description available]	1.94	1	phenylhydrazines	xenobiotic
hydrazine diamine : Any polyamine that contains two amino groups.	4.01	4	azane; hydrazines	EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
4-methylphenylhydrazine 4-methylphenylhydrazine: RN given refers to parent cpd	2.03	1
4-hydrazinobenzoic acid 4-hydrazinobenzoic acid: structure given in first source	1.99	1
7-ethoxycoumarin 7-ethoxycoumarin : A member of the class of coumarins that is umbelliferone in which the hydroxy group at position 7 is replaced by an ethoxy group.	1.99	1	aromatic ether; coumarins
chlorodiphenyl (54% chlorine) Chlorodiphenyl (54% Chlorine): A mixture of polychlorinated biphenyls that induces hepatic microsomal UDP-glucuronyl transferase activity towards thyroxine.. Aroclor 1254 : A mixture of polychlorobiphenyls of unspecified composition, containing 54% chlorine (X = Cl or H).	1.99	1
dimethylhydrazines Dimethylhydrazines: Hydrazines substituted with two methyl groups in any position.	3.06	1
gamma-l-glutaminyl-4-hydroxybenzene gamma-L-glutaminyl-4-hydroxybenzene: sulfhydryl reagent from sporulating gill of mushroom Agaricus bisporus; structure	2.39	2
vitamin d 2 Ergocalciferols: Derivatives of ERGOSTEROL formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. They differ from CHOLECALCIFEROL in having a double bond between C22 and C23 and a methyl group at C24.. vitamin D2 : A vitamin D supplement and has been isolated from alfalfa.	2.13	1	hydroxy seco-steroid; seco-ergostane; vitamin D	bone density conservation agent; nutraceutical; plant metabolite; rodenticide
cytochrome c-t Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.	2.06	1
warfarin Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.	1.99	1	benzenes; hydroxycoumarin; methyl ketone

Condition	Relationship Strength	Studies
Diffuse Large B-Cell Lymphoma [description not available]	2.06	1
Lymphoma, Large B-Cell, Diffuse Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.	2.06	1
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.43	2
Angioma A vascular anomaly due to proliferation of blood or lymphatic vessels that forms a tumor-like mass. Vessels in the angioma may or may not be dilated.	2.65	3
Angiosarcoma [description not available]	2.65	3
Cancer of Lung [description not available]	2.88	4
Germinoblastoma [description not available]	2.36	2
Experimental Neoplasms [description not available]	2.65	3
Hemangioma A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)	2.65	3
Hemangiosarcoma A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)	2.65	3
Lung Neoplasms Tumors or cancer of the LUNG.	2.88	4
Lymphoma A general term for various neoplastic diseases of the lymphoid tissue.	2.36	2
Adenocarcinoma, Basal Cell [description not available]	2.36	2
Adenoma, Basal Cell [description not available]	2.66	3
Absence Seizure [description not available]	1.96	1
Adenocarcinoma A malignant epithelial tumor with a glandular organization.	2.36	2
Adenoma A benign epithelial tumor with a glandular organization.	2.66	3
Seizures Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.	1.96	1
Mushroom Poisoning Poisoning from ingestion of mushrooms, primarily from, but not restricted to, toxic varieties.	1.98	1
Blood Vessel Tumors [description not available]	1.95	1
Bladder Cancer [description not available]	1.97	1
Urinary Bladder Neoplasms Tumors or cancer of the URINARY BLADDER.	1.97	1

agaritine

Cross-References

Synonyms (27)

Drug Classes (5)

Research

Studies (37)

Study Types

agaritine

Cross-References

Synonyms (27)

Drug Classes (5)

Research

Studies (37)

Study Types

Related Drugs (13)

Related Conditions (22)