Compounds > tetragastrin
Page last updated: 2024-09-27

tetragastrin

Description

Tetragastrin: L-Tryptophyl-L-methionyl-L-aspartyl-L-phenylalaninamide. The C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

tetragastrin : A tetrapeptide composed of L-tryptophan, L-methione, L-aspartic acid and L-phenylalaninamide residues joined in sequence. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID446569
CHEMBL ID120632
CHEBI ID137728
CHEBI ID32210
SCHEMBL ID9710792
MeSH IDM0021228

Synonyms (46)

Synonym
unii-0ol293av80
0ol293av80 ,
l-phenylalaninamide, n-((phenylmethoxy)carbonyl)-l-tryptophyl-l-methionyl-l-aspartyl-
l-phenylalaninamide, l-tryptophyl-l-methionyl-l-alpha-aspartyl-
tetragastrin [jan]
tetragastrin
l-triptophyl-l-methyionyl-l-alpha-aspartyl-l-phenylalaninamide
gastrin tetrapeptide
gastrin tetrapeptide amide
n-((phenylmethoxy)carbonyl)-l-tryptophyl-l-methionyl-l-aspartyl-l-phenylalaninamide
cholecystokinin tetrapeptide
ccris 3246
tetragastrin (jan)
D01456
1947-37-1
trp-met-asp-phe-nh(2)
cck-4
CHEBI:137728
l-tryptophyl-l-methionyl-l-alpha-aspartyl-l-phenylalaninamide
wmdf-nh(2)
cholecystokinin-4
l-trp-l-met-l-asp-l-phe-nh(2)
l-tryptophyl-l-methionyl-l-aspartyl-l-phenylalaninamide
(3s)-3-[[(2s)-2-[[(2s)-2-amino-3-(1h-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-[[(2s)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
4-7-cholecystokinin-7 (swine)
CHEMBL120632 ,
bdbm50024317
3-{2-[2-amino-3-(1h-indol-3-yl)-propionylamino]-4-methylsulfanyl-butyrylamino}-n-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid
tetragastrin [who-dd]
l-phenylalaninamide, l-tryptophyl-l-methionyl-l-.alpha.-aspartyl-
SCHEMBL9710792
mfcd00076492
gastrin(14-17)(human)
(3s)-3-[(2s)-2-[(2s)-2-amino-3-(1h-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1s)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid
SR-01000883973-1
sr-01000883973
l-tryptophyl-l-methionyl-l-aspartylphenyl-alaninamide
CHEBI:32210
(s)-4-(((s)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-3-((s)-2-((s)-2-amino-3-(1h-indol-3-yl)propanamido)-4-(methylthio)butanamido)-4-oxobutanoic acid
(s)-4-((s)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-((s)-2-((s)-2-amino-3-(1h-indol-3-yl)propanamido)-4-(methylthio)butanamido)-4-oxobutanoic acid
BRD-K70369756-001-01-3
MS-30582
DTXSID601027522
CS-0092217
HY-125556
AKOS040744602

Actions

ExcerptReference
"Tetragastrin did not increase the amino acid output in the gastric juice."( Goto, H; Kobayashi, E; Nakazawa, S; Segawa, K; Tsukamoto, Y; Yamaguchi, H, 1985)

Treatment

ExcerptReference
"Rats treated with tetragastrin or 6-OHDA had a significantly lower labelling index of the antral mucosa, and this index was significantly decreased by combined administration of tetragastrin and 6-OHDA, as compared with labeling indices observed after treatment with tetragastrin or 6-OHDA alone."( Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M, 1989)

Roles (2)

RoleDescription
anxiogenicAny psychotropic drug that induces anxiety or panic.
human metaboliteAny mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
tetrapeptideAny molecule that contains four amino-acid residues connected by peptide linkages.
peptidyl amideA peptide that has a carbamoyl group at the C-terminus.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (3)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Gastrin/cholecystokinin type B receptorRattus norvegicus (Norway rat)Ki0.09300.00060.11960.6800AID51458; AID51461
Gastrin/cholecystokinin type B receptorHomo sapiens (human)Ki0.01720.00010.03660.3450AID1409549; AID50951; AID50955
Cholecystokinin receptor type ACavia porcellus (domestic guinea pig)Ki36.13300.00030.13770.6310AID52580; AID52582
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Gastrin/cholecystokinin type B receptorRattus norvegicus (Norway rat)EC50 (µMol)0.00140.00040.00080.0014AID51295
Gastrin/cholecystokinin type B receptorHomo sapiens (human)Kd0.02170.00050.00530.0217AID1409548
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (9)

Processvia Protein(s)Taxonomy
gastric acid secretionGastrin/cholecystokinin type B receptorHomo sapiens (human)
cell surface receptor signaling pathwayGastrin/cholecystokinin type B receptorHomo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathwayGastrin/cholecystokinin type B receptorHomo sapiens (human)
positive regulation of cytosolic calcium ion concentrationGastrin/cholecystokinin type B receptorHomo sapiens (human)
positive regulation of cell population proliferationGastrin/cholecystokinin type B receptorHomo sapiens (human)
cholecystokinin signaling pathwayGastrin/cholecystokinin type B receptorHomo sapiens (human)
pH reductionGastrin/cholecystokinin type B receptorHomo sapiens (human)
digestive tract developmentGastrin/cholecystokinin type B receptorHomo sapiens (human)
gland developmentGastrin/cholecystokinin type B receptorHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (6)

Processvia Protein(s)Taxonomy
cholecystokinin receptor activityGastrin/cholecystokinin type B receptorHomo sapiens (human)
protein bindingGastrin/cholecystokinin type B receptorHomo sapiens (human)
gastrin receptor activityGastrin/cholecystokinin type B receptorHomo sapiens (human)
peptide hormone bindingGastrin/cholecystokinin type B receptorHomo sapiens (human)
type B gastrin/cholecystokinin receptor bindingGastrin/cholecystokinin type B receptorHomo sapiens (human)
1-phosphatidylinositol-3-kinase regulator activityGastrin/cholecystokinin type B receptorHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (2)

Processvia Protein(s)Taxonomy
plasma membraneGastrin/cholecystokinin type B receptorHomo sapiens (human)
intracellular membrane-bounded organelleGastrin/cholecystokinin type B receptorHomo sapiens (human)
plasma membraneGastrin/cholecystokinin type B receptorHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (12)

Assay IDTitleYearJournalArticle
AID1409549Displacement of non-sulfated CCK-8 from CCKB receptor (unknown origin) expressed in HEK cells after 4 hrs by RP-LC-ICPMS analysis2018Journal of medicinal chemistry, 11-21, Volume: 61, Issue:22
Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling.
AID51295Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.2000Journal of medicinal chemistry, Oct-05, Volume: 43, Issue:20
Replacement of glycine with dicarbonyl and related moieties in analogues of the C-terminal pentapeptide of cholecystokinin: CCK(2) agonists displaying a novel binding mode.
AID52580Inhibition of [3H]pCCK-8 binding to Cholecystokinin type A receptor of Guinea pig pancreatic membranes1997Journal of medicinal chemistry, Feb-28, Volume: 40, Issue:5
Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.
AID1409548Binding affinity to CCKB receptor (unknown origin) expressed in HEK cells after 4 hrs by RP-LC-ICPMS analysis2018Journal of medicinal chemistry, 11-21, Volume: 61, Issue:22
Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling.
AID50951Inhibition of [3H]pCCK-8 binding to Guinea pig cortex membrane Cholecystokinin type B receptor1997Journal of medicinal chemistry, Feb-28, Volume: 40, Issue:5
Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.
AID52407Displacement of [3H]pentagastrin from Cholecystokinin receptor of mouse cerebral cortex1987Journal of medicinal chemistry, Apr, Volume: 30, Issue:4
Synthesis and binding affinities of analogues of cholecystokinin-(30-33) as probes for central nervous system cholecystokinin receptors.
AID50955Binding affinity against cholecystokinin type B receptor on guinea pig cortex.2000Journal of medicinal chemistry, Oct-05, Volume: 43, Issue:20
Replacement of glycine with dicarbonyl and related moieties in analogues of the C-terminal pentapeptide of cholecystokinin: CCK(2) agonists displaying a novel binding mode.
AID52582Affinity against Cholecystokinin type A receptor on guinea pig pancreatic membranes.2000Journal of medicinal chemistry, Oct-05, Volume: 43, Issue:20
Replacement of glycine with dicarbonyl and related moieties in analogues of the C-terminal pentapeptide of cholecystokinin: CCK(2) agonists displaying a novel binding mode.
AID51461Compound was tested for binding affinity against Cholecystokinin type B receptor expressed in CHO cells on the rat brain.2000Journal of medicinal chemistry, Oct-05, Volume: 43, Issue:20
Replacement of glycine with dicarbonyl and related moieties in analogues of the C-terminal pentapeptide of cholecystokinin: CCK(2) agonists displaying a novel binding mode.
AID51458Affinity to inhibit [3H]pCCK-8 specific binding on rat brain Cholecystokinin type B receptor expressed in CHO cells1997Journal of medicinal chemistry, Feb-28, Volume: 40, Issue:5
Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.
AID231773Ratio of compound affinity on CCK-A receptor with respect to CCK-B receptor1997Journal of medicinal chemistry, Feb-28, Volume: 40, Issue:5
Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.
AID1409554Binding affinity to CCKB receptor (unknown origin) expressed in HEK cells Binding affinity to CCKB receptor (unknown origin) expressed in HEK cells assessed per million cells after 4 hrs by RP-LC-ICPMS analysis after 4 hrs by RP-LC-ICPMS analysis2018Journal of medicinal chemistry, 11-21, Volume: 61, Issue:22
Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (506)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990179 (35.38)18.7374
1990's193 (38.14)18.2507
2000's98 (19.37)29.6817
2010's34 (6.72)24.3611
2020's2 (0.40)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials72 (13.24%)5.53%
Reviews14 (2.57%)6.00%
Case Studies3 (0.55%)4.05%
Observational0 (0.00%)0.25%
Other455 (83.64%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
phenylalanine amide[no description available]medium10amino acid amide;
phenylalanine derivative
sincalide[no description available]medium1420oligopeptide
pentagastrin[no description available]medium310organic molecular entity
pentagastrin[no description available]medium312organic molecular entity
butyloxycarbonyl-tryptophyl-methionyl-aspartyl-phenylalaninamide[no description available]medium20
relcovaptan[no description available]medium10proline derivative
satavaptan[no description available]medium10
cholecystokinin[no description available]medium1094
a 71623[no description available]medium250
asperlicin[no description available]medium20
gastrins[no description available]medium1283
gastrin i[no description available]medium30
creatine[no description available]medium21glycine derivative;
guanidines;
zwitterion		geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent;
nutraceutical
glutamine[no description available]medium41amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
glutamic acid[no description available]medium61glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
gb-115[no description available]medium50
glycine[no description available]medium20alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
proline[no description available]medium30amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
tryptophan[no description available]medium91erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
neuropeptide y[no description available]medium10
arginine[no description available]medium40arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
bibp 3226[no description available]medium10
piperidines[no description available]medium51
cp 99994[no description available]medium10
substance p[no description available]medium90peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
citalopram[no description available]medium432-benzofurans;
cyclic ether;
nitrile;
organofluorine compound;
tertiary amino compound
alanine[no description available]medium11alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
glycylproline[no description available]medium10dipeptide zwitterion;
dipeptide		metabolite
prolyl-glycyl-proline[no description available]medium10peptide
l 365260[no description available]medium272benzodiazepine
desoxycorticosterone[no description available]medium2120-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
mineralocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
tiagabine[no description available]medium21beta-amino acid;
piperidinemonocarboxylic acid;
tertiary amino compound;
thiophenes		anticonvulsant;
GABA reuptake inhibitor
tetrahydrodeoxycorticosterone[no description available]medium2121-hydroxy steroid
pk 11195[no description available]medium11aromatic amide;
isoquinolines;
monocarboxylic acid amide;
monochlorobenzenes		antineoplastic agent
alprazolam[no description available]medium72organochlorine compound;
triazolobenzodiazepine		anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic
gamma-aminobutyric acid[no description available]medium71amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
rhenium[no description available]medium20manganese group element atom
perrhenate[no description available]medium10monovalent inorganic anion;
rhenium oxoanion
lorazepam[no description available]medium21benzodiazepine
sodium bicarbonate[no description available]medium10one-carbon compound;
organic sodium salt		antacid;
food anticaking agent
diazepam[no description available]medium601,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
sucrose[no description available]medium10glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
neurotensin[no description available]medium60peptide hormonehuman metabolite;
mitogen;
neurotransmitter;
vulnerary
neurotensin (8-13)[no description available]medium10
corticosterone[no description available]medium2011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
astressin[no description available]medium10homodetic cyclic peptide;
polypeptide		corticotropin-releasing factor receptor antagonist;
neuroprotective agent
phenazepam[no description available]medium10
3,4-dihydroxyphenylacetic acid[no description available]medium20catechols;
dihydroxyphenylacetic acid		human metabolite
sodium lactate[no description available]medium21lactate salt;
organic sodium salt		food acidity regulator;
food preservative
ci 988[no description available]medium72
devazepide[no description available]medium2401,4-benzodiazepinone;
indolecarboxamide		antineoplastic agent;
apoptosis inducer;
cholecystokinin antagonist;
gastrointestinal drug
meglumine[no description available]medium92hexosamine;
secondary amino compound
yohimbine[no description available]medium10methyl 17-hydroxy-20xi-yohimban-16-carboxylatealpha-adrenergic antagonist;
dopamine receptor D2 antagonist;
serotonergic antagonist
cholic acid[no description available]medium1012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
bile acid;
C24-steroid;
trihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
adamantane[no description available]medium60adamantanes;
polycyclic alkane
gv 150013x[no description available]medium30benzodiazepine
buspirone[no description available]medium20azaspiro compound;
N-alkylpiperazine;
N-arylpiperazine;
organic heteropolycyclic compound;
piperidones;
pyrimidines		anxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist
flumazenil[no description available]medium31ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist
nan 190[no description available]medium10N-alkylpiperazine;
N-arylpiperazine;
phthalimides		serotonergic antagonist
pregnanolone[no description available]medium203-hydroxy-5beta-pregnan-20-one;
3alpha-hydroxy steroid		human metabolite;
intravenous anaesthetic;
sedative
cholecystokinin 9[no description available]medium20
atropine[no description available]medium170
hexamethonium[no description available]medium50quaternary ammonium salt
ceruletide[no description available]medium180oligopeptidediagnostic agent;
gastrointestinal drug
alpha-chymotrypsin[no description available]medium30
quinazolines[no description available]medium40azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
2-(2-(5-bromo-1h-indol-3-yl)ethyl)-3-(1-methylethoxyphenyl)-4-(3h)-quinazolinone[no description available]medium60quinazolines
sr 146131[no description available]medium10
thiazoles[no description available]medium301,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
inosine[no description available]medium10inosines;
purines D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
gastrin 17[no description available]medium60gastrinantineoplastic agent
hydroxyl radical[no description available]medium10oxygen hydride;
oxygen radical;
reactive oxygen species
allopurinol[no description available]medium10nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
dimethyl sulfoxide[no description available]medium20sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
interleukin-8[no description available]medium20
butyloxycarbonyl-tryptophyl-methionyl-aspartyl-phenylalaninamide[no description available]medium120
1-(4-bromophenylaminocarbonyl)-4,5-diphenyl-3-pyrazolidinone[no description available]medium20
proglumide[no description available]medium140benzamides;
dicarboxylic acid monoamide;
glutamine derivative;
racemate		anti-ulcer drug;
cholecystokinin antagonist;
cholinergic antagonist;
delta-opioid receptor agonist;
drug metabolite;
gastrointestinal drug;
opioid analgesic;
xenobiotic metabolite
lorglumide[no description available]medium80benzamides;
dicarboxylic acid monoamide;
dichlorobenzene;
glutamic acid derivative
cr 2945[no description available]medium10
5-hydroxytryptophan[no description available]medium11hydroxytryptophanhuman metabolite;
neurotransmitter
oxidopamine[no description available]medium40benzenetriol;
catecholamine;
primary amino compound		drug metabolite;
human metabolite;
neurotoxin
sr 142801[no description available]medium11
eglumetad[no description available]medium11L-alpha-amino acid
morphine[no description available]medium40morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
megestrol[no description available]medium1117alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
tertiary alpha-hydroxy ketone		antineoplastic agent;
appetite enhancer;
contraceptive drug;
progestin;
synthetic oral contraceptive
2-amino-7-phosphonoheptanoic acid[no description available]medium10
n-methylaspartate[no description available]medium10amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent
2-amino-5-phosphonovalerate[no description available]medium10non-proteinogenic alpha-amino acidNMDA receptor antagonist
atrial natriuretic factor[no description available]medium32polypeptide
spironolactone[no description available]medium113-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
isatin[no description available]medium10indoledioneEC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite
methacholine chloride[no description available]medium20quaternary ammonium salt
albuterol[no description available]medium10phenols;
phenylethanolamines;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic
remifentanil[no description available]medium10alpha-amino acid ester;
anilide;
monocarboxylic acid amide;
piperidinecarboxylate ester		intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic;
sedative
enkephalin, leucine[no description available]medium40pentapeptide;
peptide zwitterion		analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite
angiotensin iii[no description available]medium10
angiotensin ii[no description available]medium20amino acid zwitterion;
angiotensin II		human metabolite
angiotensin i[no description available]medium10angiotensin;
peptide zwitterion		human metabolite;
neurotransmitter agent
fg 9041[no description available]medium10quinoxaline derivative
quinoxalines[no description available]medium10mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
peptide yy[no description available]medium20
oxytocin[no description available]medium31heterodetic cyclic peptide;
peptide hormone		oxytocic;
vasodilator agent
pituitrin[no description available]medium10
phosphoramidon[no description available]medium10deoxyaldohexose phosphate;
dipeptide		bacterial metabolite;
EC 3.4.24.11 (neprilysin) inhibitor;
EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitor
naloxone[no description available]medium80morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
histamine[no description available]medium361aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
apomorphine[no description available]medium70aporphine alkaloidalpha-adrenergic drug;
antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
emetic;
serotonergic drug
haloperidol[no description available]medium60aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
deoxyglucose[no description available]medium50
cimetidine[no description available]medium170aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
chlorpromazine[no description available]medium20organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
clozapine[no description available]medium10benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic
bethanechol[no description available]medium40carbamate ester;
quaternary ammonium ion		muscarinic agonist
glucagon[no description available]medium100peptide hormone
bucladesine[no description available]medium303',5'-cyclic purine nucleotide
spiperone[no description available]medium40aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
puromycin[no description available]medium20puromycinsantiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor
cholecystokinin (27-33)[no description available]medium70
leucine[no description available]medium30amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
ubenimex[no description available]medium20
thioacetamide[no description available]medium10thiocarboxamidehepatotoxic agent
methionine sulfoxide[no description available]medium10amino acid zwitterion;
L-methionine S-oxide		Escherichia coli metabolite
vasoactive intestinal peptide[no description available]medium70
methionine[no description available]medium20aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
nadp[no description available]medium10
amogastrin[no description available]medium30oligopeptide
technetium[no description available]medium30manganese group element atom
sodium pertechnetate tc 99m[no description available]medium10
beta-endorphin[no description available]medium30
hydrochloric acid[no description available]medium30chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride		mouse metabolite
n-n-propylnorapomorphine[no description available]medium10
carbachol[no description available]medium170ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic
calcimycin[no description available]medium30benzoxazole
8-bromo cyclic adenosine monophosphate[no description available]medium203',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound		antidepressant;
protein kinase agonist
c-peptide[no description available]medium10
pimagedine[no description available]medium10guanidines;
one-carbon compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 1.4.3.4 (monoamine oxidase) inhibitor
enkephalin, methionine[no description available]medium40
quipazine[no description available]medium10piperazines;
pyridines
pirenperone[no description available]medium10aromatic ketone
indomethacin[no description available]medium40aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
irsogladine[no description available]medium10dichlorobenzene
n(alpha)-benzoylarginineamide[no description available]medium10
dimyristoylphosphatidylcholine[no description available]medium101,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester		antigen;
mouse metabolite
gastrin-releasing peptide[no description available]medium20
congo red[no description available]medium20bis(azo) compound
methylnitronitrosoguanidine[no description available]medium80nitroso compoundalkylating agent
urea[no description available]medium20isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
epidermal growth factor[no description available]medium10
xenopsin[no description available]medium10
genipin[no description available]medium10iridoid monoterpenoidanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cross-linking reagent;
hepatotoxic agent;
uncoupling protein inhibitor
iridoids[no description available]medium10
aminopyrine[no description available]medium10pyrazolone;
tertiary amino compound		antipyretic;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
ceruletide diethylamine[no description available]medium10organoammonium saltdiagnostic agent;
gastrointestinal drug
cepharanthine[no description available]medium10bisbenzylisoquinoline alkaloid;
isoquinolines
nifedipine[no description available]medium10C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
cysteamine[no description available]medium10amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent
boc-tyr(s03)-nle-gly-trp-nle-asp-2-phenylethyl ester[no description available]medium30
ketanserin[no description available]medium10aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
methiothepin[no description available]medium10aryl sulfide;
dibenzothiepine;
N-alkylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist;
geroprotector;
serotonergic antagonist
senktide[no description available]medium10
cp 96345[no description available]medium10
tetrodotoxin[no description available]medium40azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
gr 82334[no description available]medium10
physalaemin[no description available]medium10
hydroxyindoleacetic acid[no description available]medium30indole-3-acetic acidsdrug metabolite;
human metabolite;
mouse metabolite
phentolamine[no description available]medium60imidazoles;
phenols;
substituted aniline;
tertiary amino compound		alpha-adrenergic antagonist;
vasodilator agent
guanethidine[no description available]medium10azocanes;
guanidines		adrenergic antagonist;
antihypertensive agent;
sympatholytic agent
lithium chloride[no description available]medium10inorganic chloride;
lithium salt		antimanic drug;
geroprotector
homovanillic acid[no description available]medium20guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite
ibotenic acid[no description available]medium10non-proteinogenic alpha-amino acidneurotoxin
a 65186[no description available]medium30
colforsin[no description available]medium10acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
intrinsic factor[no description available]medium10
ovalbumin[no description available]medium10
boranes[no description available]medium10boranes;
mononuclear parent hydride
aspartic acid[no description available]medium40aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
asparagine[no description available]medium10amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
homoserine[no description available]medium10amino acid zwitterion;
homoserine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
azaserine[no description available]medium30carboxylic ester;
diazo compound;
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antifungal agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
glutamine antagonist;
immunosuppressive agent;
metabolite
pd 135158[no description available]medium20
ds 4574[no description available]medium10
triazoles[no description available]medium101,2,3-triazole
cholecystokinin (26-33)[no description available]medium10
roxatidine acetate[no description available]medium10piperidines
famotidine[no description available]medium401,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
ku 1257[no description available]medium10piperidines
tiotidine[no description available]medium10thiazoles
imipramine[no description available]medium20dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
virginiamycin[no description available]medium10
lysine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenyl acetate[no description available]medium20benzenes;
phenyl acetates
epirizole[no description available]medium10aromatic ether
omeprazole[no description available]medium90aromatic ether;
benzimidazoles;
pyridines;
sulfoxide
acetic acid[no description available]medium20monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
ranitidine[no description available]medium10C-nitro compound;
furans;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
drug allergen;
environmental contaminant;
H2-receptor antagonist;
xenobiotic
glucosamine[no description available]medium20D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
diphenhydramine[no description available]medium20ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
threonine[no description available]medium20amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
hexanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		human metabolite;
plant metabolite
lauric acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
antibacterial agent;
plant metabolite
bradykinin[no description available]medium30oligopeptidehuman blood serum metabolite;
vasodilator agent
ng-nitroarginine methyl ester[no description available]medium20alpha-amino acid ester;
L-arginine derivative;
methyl ester;
N-nitro compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor
propranolol[no description available]medium92naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
histidine[no description available]medium10amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
1,2-bis(2-aminophenoxy)ethane-n,n,n',n'-tetraacetic acid[no description available]medium10polyamino carboxylic acid;
tetracarboxylic acid		chelator
egtazic acid[no description available]medium10diether;
tertiary amino compound;
tetracarboxylic acid		chelator
simvastatin[no description available]medium10delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic)		EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug
lovastatin[no description available]medium10delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		anticholesteremic drug;
antineoplastic agent;
Aspergillus metabolite;
prodrug
cholecystokinin pentapeptide[no description available]medium30
methoxyhydroxyphenylglycol[no description available]medium21methoxybenzenes;
phenols
phorbol 12,13-dibutyrate[no description available]medium10butyrate ester;
phorbol ester;
tertiary alpha-hydroxy ketone
cyclic gmp[no description available]medium103',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
8-bromocyclic gmp[no description available]medium103',5'-cyclic purine nucleotide;
organobromine compound		muscle relaxant;
protein kinase G agonist
phenylalanine[no description available]medium10amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
3-o-methylglucose[no description available]medium10D-aldohexose derivative
fluvoxamine[no description available]medium11(trifluoromethyl)benzenes;
5-methoxyvalerophenone O-(2-aminoethyl)oxime		antidepressant;
anxiolytic drug;
serotonin uptake inhibitor
8-hydroxy-2-(di-n-propylamino)tetralin[no description available]medium10phenols;
tertiary amino compound;
tetralins		serotonergic antagonist
a 71378[no description available]medium30
ym 022[no description available]medium10
u 73122[no description available]medium10aromatic ether;
aza-steroid;
maleimides		EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid[no description available]medium10
cholecystokinin (26-32), tyr-gly-nle(28,31) phenethyl ester-[no description available]medium10
clonidine[no description available]medium11clonidine;
imidazoline
nitroarginine[no description available]medium30guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid
pargyline[no description available]medium10aromatic amine
l 740093[no description available]medium10
lignans[no description available]medium10
honokiol[no description available]medium10biphenyls
bicuculline[no description available]medium10benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
caffeine[no description available]medium20purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
gabexate[no description available]medium10benzoate ester
ondansetron[no description available]medium22carbazoles
isoproterenol[no description available]medium31catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
isosorbide dinitrate[no description available]medium10glucitol derivative;
nitrate ester		nitric oxide donor;
vasodilator agent
racecadotril[no description available]medium10N-acyl-amino acid
thiorphan[no description available]medium30N-acyl-amino acid
spiroglumide[no description available]medium10
phosphine[no description available]medium10mononuclear parent hydride;
phosphanes;
phosphine		carcinogenic agent;
fumigant insecticide
tenatoprazole[no description available]medium10imidazopyridine
lansoprazole[no description available]medium10benzimidazoles;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
lidocaine[no description available]medium10benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic
pyrrolidonecarboxylic acid[no description available]medium105-oxoproline;
L-proline derivative;
non-proteinogenic L-alpha-amino acid		algal metabolite
substance p[no description available]medium10
substance p (5-11), pglu(5)-mephe(8)-megly(9)-[no description available]medium10
vasoactive intestinal peptide, 4-chloro-phe(6)-leu(17)-[no description available]medium10
tyrosine[no description available]medium10amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
thyroxine[no description available]medium102-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
arginine vasopressin[no description available]medium21vasopressincardiovascular drug;
hematologic agent;
mitogen
pyrophosphate[no description available]medium10diphosphate ion
copper gluconate[no description available]medium10organic molecular entity
gluconic acid[no description available]medium10gluconic acidchelator;
Penicillium metabolite
sodium borohydride[no description available]medium10inorganic sodium salt;
metal tetrahydridoborate
vigabatrin[no description available]medium10gamma-amino acidanticonvulsant;
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
natriuretic peptide, c-type[no description available]medium10
amastatin[no description available]medium10tetrapeptideEC 3.4.11.* (aminopeptidase) inhibitor;
protease inhibitor
pd 140548[no description available]medium10
dibenzylchlorethamine[no description available]medium20
metiamide[no description available]medium10imidazoles
aminophylline[no description available]medium10mixturebronchodilator agent;
cardiotonic drug
papaverine[no description available]medium10benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
neostigmine[no description available]medium20quaternary ammonium ionantidote to curare poisoning;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
xylitol[no description available]medium10
tolbutamide[no description available]medium10N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker
motilin[no description available]medium30
cholecystokinin (27-33), tert-butyloxycarbonyl-nle(28,31)-[no description available]medium10
1-amino-3-(phosphonomethylene)cyclobutane-1-carboxylic acid[no description available]medium10
pirenzepine[no description available]medium10pyridobenzodiazepineanti-ulcer drug;
antispasmodic drug;
muscarinic antagonist
hydroxyproline[no description available]medium104-hydroxyproline;
L-alpha-amino acid zwitterion		human metabolite;
mouse metabolite;
plant metabolite
trimethylenediamine[no description available]medium10alkane-alpha,omega-diaminehuman metabolite;
mouse metabolite;
reagent
eflornithine[no description available]medium10alpha-amino acid;
fluoroamino acid		trypanocidal drug
dibutyryl cyclic gmp[no description available]medium30
1-(5-isoquinolinesulfonyl)-2-methylpiperazine[no description available]medium10isoquinolines;
N-sulfonylpiperazine		EC 2.7.11.13 (protein kinase C) inhibitor
tetradecanoylphorbol acetate[no description available]medium10acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
arachidonic acid[no description available]medium10icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
enprostil[no description available]medium21
sodium hydroxide[no description available]medium20alkali metal hydroxide
prostaglandin d2[no description available]medium10prostaglandins Dhuman metabolite;
mouse metabolite
dinoprostone[no description available]medium40prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
thromboxane b2[no description available]medium10thromboxanes Bhuman metabolite;
mouse metabolite
dinoprost[no description available]medium10monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
6-ketoprostaglandin f1 alpha[no description available]medium20prostaglandins Falphahuman metabolite;
mouse metabolite
methylphenidate[no description available]medium10beta-amino acid ester;
methyl ester;
piperidines
betazole[no description available]medium21primary amino compound;
pyrazoles		diagnostic agent;
gastrointestinal drug;
histamine agonist
hydrogen[no description available]medium20elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
terbutaline[no description available]medium10phenylethanolamines;
resorcinols		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hypoglycemic agent;
sympathomimetic agent;
tocolytic agent
nizatidine[no description available]medium10
timoprazole[no description available]medium10
dextroamphetamine[no description available]medium101-phenylpropan-2-amineadrenergic agent;
adrenergic uptake inhibitor;
dopamine uptake inhibitor;
dopaminergic agent;
neurotoxin;
sympathomimetic agent
benzotript[no description available]medium10
cr 1392[no description available]medium10
alprostadil[no description available]medium11prostaglandins Eanticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent
misoprostol[no description available]medium11
guanosine triphosphate[no description available]medium10guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
halothane[no description available]medium10haloalkane;
organobromine compound;
organochlorine compound;
organofluorine compound		inhalation anaesthetic
tiopronin[no description available]medium10N-acyl-amino acid
fmrfamide[no description available]medium20
captopril[no description available]medium10alkanethiol;
L-proline derivative;
N-acylpyrrolidine;
pyrrolidinemonocarboxylic acid		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
15-keto-13,14-dihydroprostaglandin e2[no description available]medium10prostaglandins E
succinimide[no description available]medium10dicarboximide;
pyrrolidinone
bis(tert-butoxycarbonyl)oxide[no description available]medium10acyclic carboxylic anhydride
n-formylmethionylphenylalanine[no description available]medium10peptide
n-hydroxysuccinimide[no description available]medium10
carbobenzoxy chloride[no description available]medium10
lysyl-tryptophyl-alpha-lysine[no description available]medium10oligopeptide
carbonates[no description available]medium10carbon oxoanion
cholecystokinin 39[no description available]medium20
cyanogen bromide[no description available]medium10
phenylbenzoquinone[no description available]medium10
methamphetamine[no description available]medium10amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
isomethyleugenol[no description available]medium30isomethyleugenol
acetylcarnitine[no description available]low00O-acylcarnitinehuman metabolite
2-oxo-3-methylvalerate[no description available]low002-oxo monocarboxylic acid;
branched-chain keto acid		human metabolite
alpha-ketoisovalerate[no description available]low002-oxo monocarboxylic acid;
branched-chain keto acid		human metabolite;
Saccharomyces cerevisiae metabolite
2,3-diphosphoglycerate[no description available]low00bisphosphoglyceric acid;
tetronic acid derivative		human metabolite
2-keto-4-methylvalerate[no description available]low002-oxo monocarboxylic acid;
branched-chain keto acid		algal metabolite;
human metabolite
3-hydroxyanthranilic acid[no description available]low00aminobenzoic acid;
monohydroxybenzoic acid		human metabolite;
mouse metabolite
3-hydroxykynurenine[no description available]low00hydroxykynureninehuman metabolite
3-oxoadipic acid[no description available]low00dicarboxylic fatty acid;
oxo dicarboxylic acid		bacterial xenobiotic metabolite;
human metabolite
3-mercaptopyruvic acid[no description available]low002-oxo monocarboxylic acid;
thiol		antidote to cyanide poisoning;
Escherichia coli metabolite;
human metabolite;
mouse metabolite
phosphoserine[no description available]low00non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
serine derivative		human metabolite
3-phenylpropionic acid[no description available]low00benzenes;
monocarboxylic acid		antifungal agent;
human metabolite;
plant metabolite
4-hydroxyphenylacetic acid[no description available]low00monocarboxylic acid;
phenols		fungal metabolite;
human metabolite;
mouse metabolite;
plant metabolite
isocaproaldehyde[no description available]low00alpha-CH2-containing aldehydehuman metabolite;
mouse metabolite
aminolevulinic acid[no description available]low004-oxo monocarboxylic acid;
amino acid zwitterion;
delta-amino acid		antineoplastic agent;
dermatologic drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
5-aminovaleric acid[no description available]low00amino acid zwitterion;
delta-amino acid;
omega-amino fatty acid		human metabolite
acetaldehyde[no description available]low00aldehydecarcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent
acetone[no description available]low00ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
acetyl phosphate[no description available]low00acyl monophosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
adenine[no description available]low006-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
allantoin[no description available]low00imidazolidine-2,4-dione;
ureas		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite;
vulnerary
anthranilic acid[no description available]low00aminobenzoic acidhuman metabolite;
mouse metabolite
beta-alanine[no description available]low00amino acid zwitterion;
beta-amino acid		agonist;
fundamental metabolite;
human metabolite;
inhibitor;
neurotransmitter
betaine aldehyde[no description available]low00quaternary ammonium ionAspergillus metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
1-butanol[no description available]low00alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent
ureidosuccinic acid[no description available]low00aspartic acid derivative;
C4-dicarboxylic acid;
N-carbamoyl-amino acid		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
carbon monoxide[no description available]low00carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
carnitine[no description available]low00amino-acid betainehuman metabolite;
mouse metabolite
choline[no description available]low00cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
chlorine[no description available]low00halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
coumarin[no description available]low00coumarinsfluorescent dye;
human metabolite;
plant metabolite
aminoethylphosphonic acid[no description available]low00phosphonic acids;
primary amino compound;
zwitterion		human metabolite;
metabolite;
mouse metabolite
octanoic acid[no description available]low00medium-chain fatty acid;
straight-chain saturated fatty acid		antibacterial agent;
Escherichia coli metabolite;
human metabolite
dihydrolipoic acid[no description available]low00thio-fatty acidantioxidant;
human metabolite;
neuroprotective agent
3-hydroxybutyric acid[no description available]low00(omega-1)-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
hydroxybutyric acid		human metabolite
methylmalonic acid[no description available]low00C4-dicarboxylic acidhuman metabolite
pyrrolidonecarboxylic acid[no description available]low00oxoproline;
pyrrolidin-2-ones;
pyrrolidinemonocarboxylic acid		human metabolite
alpha-keto-delta-guanidinovaleric acid[no description available]low002-oxo monocarboxylic acid;
zwitterion		human metabolite;
mouse metabolite
cytosine[no description available]low00aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dihydrouracil[no description available]low00pyrimidoneEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
dihydrolipoamide[no description available]low00dithiol;
monocarboxylic acid amide		cofactor;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dihydroxyacetone phosphate[no description available]low00glycerone phosphates;
primary alpha-hydroxy ketone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dihydroxyacetone[no description available]low00ketotriose;
primary alpha-hydroxy ketone		antifungal agent;
Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dimethylglycine[no description available]low00amino acid zwitterion;
N-methyl-amino acid;
N-methylglycines		Daphnia magna metabolite;
human metabolite;
mouse metabolite
5,6-dimethylbenzimidazole[no description available]low00dimethylbenzimidazoleEscherichia coli metabolite;
human metabolite
ethanolamine[no description available]low00ethanolamines;
primary alcohol;
primary amine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
gamma-butyrobetaine[no description available]low00amino-acid betaineEscherichia coli metabolite;
human metabolite
glutaric acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		Daphnia magna metabolite;
human metabolite
glycerol[no description available]low00alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
alpha-glycerophosphoric acid[no description available]low00glycerol monophosphatealgal metabolite;
human metabolite
glycolaldehyde[no description available]low00glycolaldehydesfundamental metabolite;
human metabolite
glyoxylic acid[no description available]low002-oxo monocarboxylic acid;
aldehydic acid		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
glycocyamine[no description available]low00guanidinoacetic acids;
zwitterion		bacterial metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite
hydrogen cyanide[no description available]low00hydracid;
one-carbon compound		Escherichia coli metabolite;
human metabolite;
poison
hydrogen carbonate[no description available]low00carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
homogentisic acid[no description available]low00dihydroxyphenylacetic acid;
hydroquinones		human metabolite;
plant metabolite
indole-3-acetaldehyde[no description available]low00indoleacetaldehydebacterial metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
indoleacetic acid[no description available]low00indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite
itaconic acid[no description available]low00dicarboxylic acid;
dicarboxylic fatty acid;
olefinic compound		fungal metabolite;
human metabolite
potassium[no description available]low00alkali metal cation;
elemental potassium;
monoatomic monocation;
monovalent inorganic cation		cofactor;
human metabolite
dihydroxyphenylalanine[no description available]low00hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative		human metabolite
kynurenine[no description available]low00aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline		human metabolite
lipoamide[no description available]low00dithiolanes;
monocarboxylic acid amide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
malonic acid[no description available]low00alpha,omega-dicarboxylic acidhuman metabolite
methylmercaptan[no description available]low00alkanethiolhuman metabolite;
Saccharomyces cerevisiae metabolite
pyruvaldehyde[no description available]low002-oxo aldehyde;
propanals		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
methanol[no description available]low00alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
melatonin[no description available]low00acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger
n-acetylserotonin[no description available]low00acetamides;
N-acylserotonin;
phenols		antioxidant;
human metabolite;
mouse metabolite;
tropomyosin-related kinase B receptor agonist
n-methylphenylethanolamine[no description available]low00alkaloid;
phenylethanolamines		human metabolite;
plant metabolite
n'-acetylspermine[no description available]low00acetamides;
acetylspermine		human metabolite
nitrites[no description available]low00monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species		human metabolite
hydroxypyruvic acid[no description available]low002-oxo monocarboxylic acid;
3-hydroxy monocarboxylic acid;
primary alpha-hydroxy ketone		Escherichia coli metabolite;
human metabolite
oxalic acid[no description available]low00alpha,omega-dicarboxylic acidalgal metabolite;
human metabolite;
plant metabolite
4-hydroxyphenylpyruvic acid[no description available]low002-oxo monocarboxylic acid;
phenols		human metabolite
hexadecanal[no description available]low002,3-saturated fatty aldehyde;
long-chain fatty aldehyde		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
phenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
phenylacetic acid[no description available]low00benzenes;
monocarboxylic acid;
phenylacetic acids		allergen;
Aspergillus metabolite;
auxin;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
Escherichia coli metabolite;
human metabolite;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite;
toxin
2-hydroxyphenethylamine[no description available]low00phenylethanolamineshuman metabolite
phenethylamine[no description available]low00alkaloid;
aralkylamine;
phenylethylamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
phosphoric acid[no description available]low00phosphoric acidsalgal metabolite;
fertilizer;
human metabolite;
NMR chemical shift reference compound;
solvent
phosphorylcholine[no description available]low00phosphocholinesallergen;
epitope;
hapten;
human metabolite;
mouse metabolite
phosphorylethanolamine[no description available]low00phosphoethanolamine;
primary amino compound		algal metabolite;
human metabolite;
mouse metabolite
picolinic acid[no description available]low00pyridinemonocarboxylic acidhuman metabolite;
MALDI matrix material
pyridoxal[no description available]low00hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxal phosphate[no description available]low00methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxamine[no description available]low00aminoalkylpyridine;
hydroxymethylpyridine;
monohydroxypyridine;
vitamin B6		Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite
pyridoxamine phosphate[no description available]low00aminoalkylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6 phosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxine[no description available]low00hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
quinolinic acid[no description available]low00pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
thiosulfates[no description available]low00divalent inorganic anion;
sulfur oxide;
sulfur oxoanion		human metabolite
sarcosine[no description available]low00N-alkylglycine zwitterion;
N-alkylglycine;
N-methyl-amino acid;
N-methylglycines		Escherichia coli metabolite;
glycine receptor agonist;
glycine transporter 1 inhibitor;
human metabolite;
mouse metabolite
taurine[no description available]low00amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
thiamine[no description available]low00primary alcohol;
vitamin B1		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
thymine[no description available]low00pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite
2-(4-methyl-1,3-thiazol-5-yl)ethanol[no description available]low001,3-thiazoles;
primary alcohol		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
tryptamine[no description available]low00aminoalkylindole;
aralkylamino compound;
indole alkaloid;
tryptamines		human metabolite;
mouse metabolite;
plant metabolite
uracil[no description available]low00pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
uric acid[no description available]low00uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
vanilmandelic acid[no description available]low002-hydroxy monocarboxylic acid;
aromatic ether;
phenols		human metabolite
perillic acid[no description available]low00alpha,beta-unsaturated monocarboxylic acid;
cyclohexenecarboxylic acid		antineoplastic agent;
human metabolite;
mouse metabolite
meglutol[no description available]low003-hydroxy carboxylic acid;
dicarboxylic acid;
tertiary alcohol		anticholesteremic drug;
antimetabolite;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
human metabolite;
plant metabolite
3-hydroxy-4-methoxyphenethylamine[no description available]low00monomethoxybenzene;
phenols;
phenylethylamine;
primary amino compound		human metabolite;
rat metabolite
5-methoxytryptamine[no description available]low00aromatic ether;
primary amino compound;
tryptamines		5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist
cetyl alcohol[no description available]low00hexadecanol;
long-chain primary fatty alcohol		algal metabolite;
flavouring agent;
human metabolite;
plant metabolite
4-cresol[no description available]low00cresolEscherichia coli metabolite;
human metabolite;
uremic toxin
debrisoquin[no description available]low00carboxamidine;
isoquinolines		adrenergic agent;
antihypertensive agent;
human metabolite;
sympatholytic agent
decanoic acid[no description available]low00medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
anti-inflammatory agent;
antibacterial agent;
human metabolite;
plant metabolite;
volatile oil component
nordazepam[no description available]low001,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
GABA modulator;
human metabolite;
sedative
2,5-dihydroxybenzoic acid[no description available]low00dihydroxybenzoic acidEC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
fungal metabolite;
human metabolite;
MALDI matrix material;
mouse metabolite
tele-methylhistamine[no description available]low00imidazoles;
primary amino compound		human metabolite;
mouse metabolite
indolepropionic acid[no description available]low00indol-3-yl carboxylic acidauxin;
human metabolite;
plant metabolite
kynurenic acid[no description available]low00monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite
3-phenyllactic acid[no description available]low002-hydroxy monocarboxylic acidhuman metabolite
2-amino-3-phosphonopropionic acid[no description available]low00alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids		human metabolite;
metabotropic glutamate receptor antagonist
2-phenylglycine[no description available]low00non-proteinogenic alpha-amino acidhuman metabolite
sebacic acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite;
plant metabolite
stearic acid[no description available]low00long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite
succinylacetone[no description available]low00beta-diketone;
dioxo monocarboxylic acid		human metabolite
retinoic acid[no description available]low00alpha,beta-unsaturated monocarboxylic acid;
retinoid		human metabolite
tyramine[no description available]low00monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
estriol[no description available]low0016alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid		estrogen;
human metabolite;
human xenobiotic metabolite;
mouse metabolite
sorbitol[no description available]low00glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
thymidine[no description available]low00pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
aldosterone[no description available]low0011beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde		human metabolite;
mouse metabolite
cysteine[no description available]low00cysteine zwitterion;
cysteine;
L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid		EC 4.3.1.3 (histidine ammonia-lyase) inhibitor;
flour treatment agent;
human metabolite
estrone[no description available]low0017-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite
androsterone[no description available]low0017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid		androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone
etiocholanolone[no description available]low0017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid		human metabolite;
mouse metabolite
dehydroepiandrosterone[no description available]low0017-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid		androgen;
human metabolite;
mouse metabolite
triiodothyronine[no description available]low002-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
isonicotinic acid[no description available]low00pyridinemonocarboxylic acidalgal metabolite;
human metabolite
serine[no description available]low00L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
adenosine diphosphate[no description available]low00adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
uridine[no description available]low00uridinesdrug metabolite;
fundamental metabolite;
human metabolite
uridine monophosphate[no description available]low00pyrimidine ribonucleoside 5'-monophosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
levodopa[no description available]low00amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug
androstenedione[no description available]low0017-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
cytidine monophosphate[no description available]low00cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
cytidine[no description available]low00cytidinesEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
17-alpha-hydroxyprogesterone[no description available]low0017alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone		human metabolite;
metabolite;
mouse metabolite;
progestin
n-pentanol[no description available]low00pentanol;
short-chain primary fatty alcohol		human metabolite;
plant metabolite
valine[no description available]low00L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
isoleucine[no description available]low00aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
ethylamine[no description available]low00primary aliphatic aminehuman metabolite
taurocholic acid[no description available]low00amino sulfonic acid;
bile acid taurine conjugate		human metabolite
skatole[no description available]low00methylindolehuman metabolite;
mammalian metabolite
quinaldic acid[no description available]low00quinolinemonocarboxylic acidhuman metabolite;
Saccharomyces cerevisiae metabolite
3-methylpentane[no description available]low00alkane;
volatile organic compound		allelochemical;
human metabolite;
non-polar solvent
methylcyclopentane[no description available]low00cycloalkane;
volatile organic compound		human metabolite;
plant metabolite
phosphoribosyl pyrophosphate[no description available]low005-O-phosphono-D-ribofuranosyl diphosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
1-phenethylamine[no description available]low00phenylethylaminehuman metabolite
trehalose[no description available]low00trehaloseEscherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
isethionic acid[no description available]low00alkanesulfonic acidhuman metabolite
methylcyclohexane[no description available]low00cycloalkane;
volatile organic compound		aprotic solvent;
human metabolite;
plant metabolite
piperidine[no description available]low00azacycloalkane;
piperidines;
saturated organic heteromonocyclic parent;
secondary amine		base;
catalyst;
human metabolite;
non-polar solvent;
plant metabolite;
protic solvent;
reagent
undecanoic acid[no description available]low00medium-chain fatty acid;
straight-chain saturated fatty acid		antifungal agent;
human metabolite
1-tridecanol[no description available]low00long-chain primary fatty alcohol;
tridecanol		bacterial metabolite;
human metabolite;
plant metabolite
stearyl alcohol[no description available]low00long-chain primary fatty alcohol;
octadecanol		algal metabolite;
human metabolite;
plant metabolite
acetol[no description available]low00methyl ketone;
primary alcohol;
primary alpha-hydroxy ketone;
propanones		Escherichia coli metabolite;
human metabolite;
mouse metabolite
2-methylbutanoic acid[no description available]low00methylbutyric acidbacterial metabolite;
human metabolite
isopropyl palmitate[no description available]low00fatty acid ester;
isopropyl ester		human metabolite
pregnenolone[no description available]low0020-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
C21-steroid		human metabolite;
mouse metabolite
20-alpha-dihydroprogesterone[no description available]low0020-hydroxypregn-4-en-3-onehuman metabolite;
mouse metabolite
homoarginine[no description available]low00homoarginine;
L-lysine derivative;
non-proteinogenic L-alpha-amino acid		biomarker;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
human metabolite;
rat metabolite;
xenobiotic metabolite
dibenzo(a,l)pyrene[no description available]low00ortho- and peri-fused polycyclic arenehuman metabolite;
mutagen
diiodotyrosine[no description available]low00diiodotyrosine;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite
3-methoxytyrosine[no description available]low00aromatic L-alpha-amino acid zwitterion;
L-tyrosine derivative;
monomethoxybenzene;
non-proteinogenic L-alpha-amino acid		human metabolite
thiocyanate[no description available]low00pseudohalide anion;
sulfur molecular entity		human metabolite
4-hydroxyphenyllactic acid[no description available]low002-hydroxy carboxylic acid;
phenols		bacterial metabolite;
human metabolite
citrulline[no description available]low00amino acid zwitterion;
citrulline		Daphnia magna metabolite;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
protective agent;
Saccharomyces cerevisiae metabolite
lithocholic acid[no description available]low00bile acid;
C24-steroid;
monohydroxy-5beta-cholanic acid		geroprotector;
human metabolite;
mouse metabolite
nandrolone[no description available]low0017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
anabolic androgenic steroid		human metabolite
4-methylcatechol[no description available]low00methylcatecholantioxidant;
carcinogenic agent;
hapten;
human metabolite;
plant metabolite
homocystine[no description available]low00amino acid zwitterion;
homocystines		human metabolite
chenodeoxycholic acid[no description available]low00bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
glycocholic acid[no description available]low00bile acid glycine conjugatehuman metabolite
epitestosterone[no description available]low0017alpha-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen antagonist;
human metabolite
ninhydrin[no description available]low00aromatic ketone;
beta-diketone;
indanones;
ketone hydrate		colour indicator;
human metabolite
indican[no description available]low00aryl sulfate;
indoles		human metabolite
suberic acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
hexadecanedioic acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
androstenediol[no description available]low0017beta-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid		androgen;
human metabolite;
mouse metabolite;
radiation protective agent
dihydrotestosterone[no description available]low0017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
pyridoxamine dihydrochloride[no description available]low00hydrochloride;
vitamin B6		Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite
aceturic acid[no description available]low00N-acetyl-amino acid;
N-acylglycine		human metabolite
myristic acid[no description available]low00long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite
glycylglycine[no description available]low00dipeptide zwitterion;
dipeptide		human metabolite
lignoceric acid[no description available]low00straight-chain saturated fatty acid;
very long-chain fatty acid		Daphnia tenebrosa metabolite;
human metabolite;
plant metabolite;
volatile oil component
18-hydroxycorticosterone[no description available]low0011beta-hydroxy steroid;
18-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo steroid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
2-hydroxybutyric acid[no description available]low002-hydroxy monocarboxylic acid;
hydroxybutyric acid		algal metabolite;
human metabolite
3-methylhexane[no description available]low00alkane;
volatile organic compound		human metabolite
ethylmalonic acid[no description available]low00dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
galactitol[no description available]low00hexitolEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
2-hydroxyphenylacetic acid[no description available]low00hydroxy monocarboxylic acid;
phenols		human metabolite;
mouse metabolite
acetylcysteine[no description available]low00acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
5-methyl-2-furfural[no description available]low00aldehyde;
furans		EC 2.2.1.6 (acetolactate synthase) inhibitor;
flavouring agent;
human metabolite;
Maillard reaction product
2-hexanol[no description available]low00hexanol;
secondary alcohol		human metabolite;
plant metabolite;
semiochemical
1,1,3,3-tetramethylurea[no description available]low00ureashuman metabolite
glycochenodeoxycholic acid[no description available]low00bile acid glycine conjugatehuman metabolite
isocaproic acid[no description available]low00branched-chain saturated fatty acid;
medium-chain fatty acid;
methyl-branched fatty acid		human metabolite
dehydroepiandrosterone sulfate[no description available]low0017-oxo steroid;
steroid sulfate		EC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite;
mouse metabolite
dodecanedioic acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		EC 1.1.1.1 (alcohol dehydrogenase) inhibitor;
human metabolite
deoxycytidine[no description available]low00pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyuridine[no description available]low00pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2'-deoxyadenosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
cytidine diphosphate choline[no description available]low00nucleotide-(amino alcohol)s;
phosphocholines		human metabolite;
mouse metabolite;
neuroprotective agent;
psychotropic drug;
Saccharomyces cerevisiae metabolite
1-pentene-3-one[no description available]low00enoneflavouring agent;
genotoxin;
human metabolite;
plant metabolite
5 alpha-androstane-3 alpha,17 beta-diol[no description available]low00androstane-3alpha,17beta-diolDaphnia magna metabolite;
human metabolite
9,10-epoxystearic acid[no description available]low00epoxystearic acidhuman metabolite
5-hydroxyindole[no description available]low00hydroxyindoleshuman metabolite
beta-hydroxymyristic acid[no description available]low003-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
long-chain fatty acid		bacterial metabolite;
human metabolite
perillaldehyde[no description available]low00aldehyde;
olefinic compound		human metabolite;
mouse metabolite;
volatile oil component
tricosanoic acid[no description available]low00straight-chain saturated fatty acid;
very long-chain fatty acid		Daphnia magna metabolite;
human metabolite;
plant metabolite
uridine diphosphate glucuronic acid[no description available]low00UDP-D-glucuronic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
tetrahydropapaveroline[no description available]low00benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
isoquinolinol		human metabolite
dithiothreitol[no description available]low001,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
cyclic cmp[no description available]low003',5'-cyclic pyrimidine nucleotidehuman metabolite
furoylglycine[no description available]low00furans;
N-acylglycine		human metabolite
3,3',5'-triiodothyronine[no description available]low00iodothyroninehuman metabolite
limonene[no description available]low00cycloalkene;
p-menthadiene		human metabolite
hypochlorous acid[no description available]low00chlorine oxoacid;
reactive oxygen species		EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite
urobilinogen[no description available]low00bilaneshuman metabolite
estetrol[no description available]low0015alpha-hydroxy steroid;
16alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid;
steroid hormone		estrogen receptor agonist;
estrogen;
human metabolite;
human xenobiotic metabolite;
oral contraceptive
iron[no description available]low00divalent metal cation;
iron cation;
monoatomic dication		cofactor;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
1-methyladenosine[no description available]low00methyladenosinehuman metabolite
iodine[no description available]low00halide anion;
monoatomic iodine		human metabolite
nonanal[no description available]low00medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		human metabolite;
plant metabolite
dimethylacetamide[no description available]low00acetamides;
monocarboxylic acid amide		human metabolite
ursodeoxycholic acid[no description available]low00bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
s-adenosylmethionine[no description available]low00sulfonium betainehuman metabolite
acetylgalactosamine[no description available]low00N-acetyl-D-hexosamine;
N-acetylgalactosamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
paclitaxel[no description available]low00taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
norsalsolinol[no description available]low00isoquinolinolanimal metabolite;
apoptosis inducer;
human metabolite;
marine metabolite
2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline[no description available]low00isoquinolinol;
tertiary amino compound		human metabolite;
neurotoxin;
rat metabolite
adenosine[no description available]low00adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
d-lactic acid[no description available]low002-hydroxypropanoic acidEscherichia coli metabolite;
human metabolite
xanthosine[no description available]low00purines D-ribonucleoside;
xanthosines		Escherichia coli metabolite;
human metabolite;
mouse metabolite
1,5-anhydroglucitol[no description available]low00anhydro sugarhuman metabolite
3-methylhistidine[no description available]low00L-histidine derivative;
non-proteinogenic L-alpha-amino acid;
zwitterion		human metabolite;
Saccharomyces cerevisiae metabolite
5-methylcytosine[no description available]low00methylcytosine;
pyrimidines		human metabolite
n-acetylaspartic acid[no description available]low00N-acetyl-L-amino acid;
N-acyl-L-aspartic acid		antioxidant;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite
deoxyuridine triphosphate[no description available]low00deoxyuridine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite
homocitrulline[no description available]low00amino acid zwitterion;
L-lysine derivative;
non-proteinogenic L-alpha-amino acid;
ureas		human metabolite;
mouse metabolite
cholesteryl sulfate[no description available]low00steroid sulfatehuman metabolite
2'-deoxycytidine 5'-triphosphate[no description available]low002'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
25-hydroxycholesterol[no description available]low0025-hydroxy steroid;
oxysterol		human metabolite
aica ribonucleotide[no description available]low001-(phosphoribosyl)imidazolecarboxamide;
aminoimidazole		cardiovascular drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
n-acetylserine[no description available]low00acetyl-L-serine;
N-acetyl-L-amino acid		human metabolite
o-4-methylthymine[no description available]low00aromatic ether;
methylthymine		human metabolite
tetraiodothyroacetic acid[no description available]low002-halophenol;
aromatic ether;
iodophenol;
monocarboxylic acid		apoptosis inducer;
human metabolite;
thyroid hormone
lathosterol[no description available]low003beta-sterol;
C27-steroid;
cholestanoid;
Delta(7)-sterol		human metabolite;
mouse metabolite
omega-aminocaprylic acid[no description available]low00medium-chain fatty acid;
omega-amino fatty acid		human metabolite
2-methoxyestradiol[no description available]low0017beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite
parabanic acid[no description available]low00hydracid;
imidazolidinone		human metabolite
n-acetyl-l-arginine[no description available]low00N-acetyl-L-amino acidhuman metabolite
cystine[no description available]low00cystine zwitterion;
cystine;
L-cysteine derivative;
non-proteinogenic L-alpha-amino acid		EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
6-methyladenine[no description available]low006-alkylaminopurine;
methyladenine		human metabolite
phenylacetylglycine[no description available]low00monocarboxylic acid amide;
monocarboxylic acid;
N-acylglycine		human metabolite;
mouse metabolite
hydracrylic acid[no description available]low003-hydroxy monocarboxylic acid;
omega-hydroxy-short-chain fatty acid		Escherichia coli metabolite;
human metabolite
hordenine[no description available]low00phenethylamine alkaloidhuman metabolite;
mouse metabolite
4-methoxyestradiol[no description available]low0017beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
phenols		estrogen;
human metabolite;
rat metabolite
glutaurine[no description available]low00dipeptide zwitterion;
dipeptide;
L-glutamine derivative;
sulfonic acid		anticonvulsant;
anxiolytic drug;
hormone;
human metabolite;
mammalian metabolite;
mouse metabolite
plasmenylserine[no description available]low00O-phosphoserineEC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor;
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
ubiquinone-o[no description available]low00ubiquinonesEscherichia coli metabolite;
human metabolite
beta-hydroxyisovaleric acid[no description available]low003-hydroxy monocarboxylic acidhuman metabolite
n-acetylhistamine[no description available]low00acetamides;
imidazoles		human metabolite
indole-3-carboxylic acid[no description available]low00indol-3-yl carboxylic acidbacterial metabolite;
human metabolite
5-hydroxymethylcytosine[no description available]low00aminopyrimidine;
aromatic primary alcohol;
nucleobase analogue;
pyrimidone		human metabolite;
mouse metabolite
n-acetylglutamic acid[no description available]low00N-acetyl-L-amino acid;
N-acyl-L-glutamic acid		human metabolite;
Saccharomyces cerevisiae metabolite
2,5-dihydroxybenzaldehyde[no description available]low00dihydroxybenzaldehydehuman metabolite;
mouse metabolite;
Penicillium metabolite
D-serine[no description available]low00D-alpha-amino acid;
serine zwitterion;
serine		Escherichia coli metabolite;
human metabolite;
NMDA receptor agonist
D-alanine[no description available]low00alanine zwitterion;
alanine;
D-alpha-amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite
2-ketopentanoic acid[no description available]low002-oxo monocarboxylic acid;
oxopentanoic acid		human metabolite
hydroxyindoleacetaldehyde[no description available]low00hydroxyindoles;
indoleacetaldehyde		human metabolite;
mouse metabolite
leucylleucine[no description available]low00dipeptide;
L-aminoacyl-L-amino acid zwitterion		human metabolite;
Mycoplasma genitalium metabolite
5-hydroxymethyluracil[no description available]low00primary alcohol;
pyrimidone		human metabolite
12-hydroxydodecanoic acid[no description available]low00omega-hydroxy-medium-chain fatty acidhuman metabolite
decane-1,2-diol[no description available]low00glycol;
volatile organic compound		anti-inflammatory agent;
antioxidant;
human metabolite
4-nitrophenyl sulfate[no description available]low00aryl sulfate;
C-nitro compound		human metabolite
glucose-1,6-bisphosphate[no description available]low00D-glucose 1,6-bisphosphateEscherichia coli metabolite;
human metabolite
biotinamide[no description available]low00biotins;
monocarboxylic acid amide		human metabolite
3,4-dihydroxymandelic acid[no description available]low002-hydroxy monocarboxylic acid;
catechols		antioxidant;
drug metabolite;
human metabolite;
mouse metabolite
3-hydroxymandelic acid[no description available]low002-hydroxy monocarboxylic acid;
phenols		human metabolite
n-acetylalanine[no description available]low00L-alanine derivative;
N-acetyl-L-amino acid		human metabolite;
Saccharomyces cerevisiae metabolite
17-alpha-hydroxypregnenolone[no description available]low0017alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
hydroxypregnenolone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
cholest-4-en-3-one[no description available]low003-oxo-Delta(4) steroid;
cholestanoid		human metabolite;
plant metabolite
mephentermine[no description available]low002-aminooctadecane-1,3-diolEC 2.7.11.13 (protein kinase C) inhibitor;
human metabolite;
mouse metabolite
2-pinene oxide[no description available]low00epoxide;
pinane monoterpenoid		bacterial xenobiotic metabolite;
fragrance;
human metabolite
1-methylhistidine[no description available]low00L-histidine derivative;
non-proteinogenic L-alpha-amino acid;
zwitterion		human metabolite
3-hydroxybutyric acid[no description available]low003-hydroxybutyric acid;
ketone body		fungal metabolite;
human metabolite;
pheromone
L-2-aminoadipic acid[no description available]low002-aminoadipic acidEscherichia coli metabolite;
human metabolite
testosterone acetate[no description available]low003-oxo-Delta(4) steroid;
androstanoid;
sterol ester		human metabolite
phenylacetylglutamine[no description available]low00N(2)-phenylacetylglutaminehuman metabolite
5beta-pregnane-3,20-dione[no description available]low0020-oxo steroid;
3-oxo-5beta-steroid;
C21-steroid		human metabolite;
mouse metabolite
zymosterol[no description available]low003beta-sterol;
cholestanoid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
brexanolone[no description available]low003-hydroxy-5alpha-pregnan-20-oneantidepressant;
GABA modulator;
human metabolite;
intravenous anaesthetic;
sedative
5-alpha-dihydroprogesterone[no description available]low0020-oxo steroid;
3-oxo-5alpha-steroid;
C21-steroid hormone		human metabolite;
progestogen
n-epsilon-acetyllysine[no description available]low00acetyl-L-lysine;
amino acid zwitterion;
N(6)-acyl-L-lysine		human metabolite
2-hydroxyhexadecanoic acid[no description available]low002-hydroxy fatty acid;
hydroxypalmitic acid		human metabolite
19-oxo-delta(4) androstene-3,17-dione[no description available]low0017-oxo steroid;
19-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid;
steroid aldehyde		human metabolite
gamma-glutamylglutamate[no description available]low00dipeptidehuman metabolite
indole-3-lactic acid[no description available]low00hydroxy monocarboxylic acid;
indol-3-yl carboxylic acid		human metabolite
n(alpha)-acetyllysine[no description available]low00acetyl-L-lysine;
amino acid zwitterion		human metabolite
glycyl-l-phenylalanine[no description available]low00dipeptide zwitterion;
dipeptide		human metabolite;
metabolite
5,6-dihydrothymine[no description available]low00pyrimidonehuman metabolite;
metabolite;
mouse metabolite
gamma-glutamyltyrosine[no description available]low00dicarboxylic acid;
dipeptide;
phenols;
primary amino compound;
secondary carboxamide		human metabolite
cholest-5-ene-3 beta,26-diol[no description available]low0026-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol		EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite
2-hydroxyisovaleric acid[no description available]low002-hydroxy monocarboxylic acidhuman metabolite
aminomalonic acid[no description available]low00amino dicarboxylic acidDaphnia magna metabolite;
human metabolite
zymostenol[no description available]low003beta-sterol;
cholestanoid		human metabolite;
mouse metabolite
16-hydroxydehydroepiandrosterone[no description available]low0016alpha-hydroxy steroid;
17-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid;
secondary alpha-hydroxy ketone		human metabolite;
mouse metabolite
cortisol 21-sulfate[no description available]low0011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
cortisol ester;
steroid sulfate;
tertiary alpha-hydroxy ketone		human metabolite
1,2-distearoylphosphatidylethanolamine[no description available]low00phosphatidylethanolamine zwitterion;
phosphatidylethanolamine		human metabolite
hydrogen sulfite[no description available]low00sulfur oxoanionhuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
aflatoxin b1-2,3-oxide[no description available]low00aflatoxinhuman metabolite
fructose 2,6-diphosphate[no description available]low00D-fructofuranose 2,6-bisphosphatehuman metabolite;
mouse metabolite
pregnenolone sulfate[no description available]low00steroid sulfateEC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite
3,3'-diiodothyronine[no description available]low003,3'-diiodothyronine;
amino acid zwitterion		human metabolite
l-lactic acid[no description available]low00(2S)-2-hydroxy monocarboxylic acid;
2-hydroxypropanoic acid		Escherichia coli metabolite;
human metabolite
propionylcarnitine[no description available]low00O-acylcarnitineanalgesic;
antirheumatic drug;
cardiotonic drug;
human metabolite;
peripheral nervous system drug
hypotaurine[no description available]low00aminosulfinic acid;
zwitterion		human metabolite;
metabolite;
mouse metabolite
testosterone 17-glucosiduronate[no description available]low003-oxo steroid;
beta-D-glucosiduronic acid;
enone;
steroid glucosiduronic acid		human metabolite
3-chloro-L-tyrosine[no description available]low00chloroamino acid;
L-alpha-amino acid zwitterion;
L-tyrosine derivative;
monochlorobenzenes;
non-proteinogenic L-alpha-amino acid		biomarker;
human metabolite
androsterone glucuronide[no description available]low00beta-D-glucosiduronic acid;
steroid glucosiduronic acid		human metabolite;
metabolite;
mouse metabolite
selenomethylselenocysteine[no description available]low00non-proteinogenic alpha-amino acid;
selenocysteines		antineoplastic agent;
human metabolite
1,5(10)-estradiene-3,4,17-trione[no description available]low0017-oxo steroid;
3-oxo-Delta(1) steroid;
orthoquinones		human metabolite
s-sulphocysteine[no description available]low00organic thiosulfate;
S-substituted L-cysteine		human metabolite;
plant metabolite
estrone-3-glucuronide[no description available]low0017-oxo steroid;
beta-D-glucosiduronic acid;
steroid glucosiduronic acid		human metabolite;
mouse metabolite
3,4-dihydroxyphenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
catechols;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite
caprylates[no description available]low00fatty acid anion 8:0;
straight-chain saturated fatty acid anion		human metabolite;
Saccharomyces cerevisiae metabolite
1-hydroxyethyl radical[no description available]low00organic anionhuman metabolite;
Saccharomyces cerevisiae metabolite
(20s)-20-hydroxycholesterol[no description available]low0020-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol		human metabolite;
mouse metabolite
deoxyhypusine[no description available]low00L-lysine derivative;
non-proteinogenic L-alpha-amino acid		human metabolite
3,7,12-trihydroxycoprostanic acid[no description available]low0012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
cholestanoic acid;
hydroxy monocarboxylic acid		human metabolite
triiodothyronine sulfate[no description available]low00aryl sulfate;
O-sulfoamino acid		human metabolite
3,7,12-trihydroxycholestan-26-oic acid[no description available]low0012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
hydroxy monocarboxylic acid;
steroid acid		human metabolite
erythrose 4-phosphate[no description available]low00erythrose phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
n(8)-acetylspermidine[no description available]low00acetylspermidineEscherichia coli metabolite;
human metabolite
7 alpha-hydroxy-4-cholesten-3-one[no description available]low003-oxo-Delta(4) steroid;
7alpha-hydroxy steroid;
cholestanoid		human metabolite;
mouse metabolite
pristanic acid[no description available]low00branched-chain saturated fatty acid;
long-chain fatty acid;
methyl-branched fatty acid		human metabolite
gamma-glutamylcysteine[no description available]low00gamma-glutamylcysteineEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
27-hydroxycholesterol[no description available]low0026-hydroxycholesterolapoptosis inducer;
human metabolite;
mouse metabolite;
neuroprotective agent
3-carboxy-4-methyl-5-propyl-2-furanpropionic acid[no description available]low00dicarboxylic acid;
furoic acid		human metabolite;
uremic toxin
dehydroalanine[no description available]low002,3-dehydroamino acid;
alpha,beta-unsaturated monocarboxylic acid;
amino acid zwitterion;
enamine;
non-proteinogenic alpha-amino acid		alkylating agent;
human metabolite;
mouse metabolite
hypothiocyanite ion[no description available]low00one-carbon compound;
sulfur oxoacid		antibacterial agent;
antifungal agent;
antiviral agent;
human metabolite;
oxidising agent;
rat metabolite
3-c-methylerythritol[no description available]low00tetritolhuman metabolite
succinylacetoacetate[no description available]low00alpha,omega-dicarboxylic acid;
beta-diketone		human metabolite
isoursodeoxycholic acid[no description available]low00dihydroxy-5beta-cholanic acidhuman metabolite
mannitol-1-phosphate[no description available]low00alditol 1-phosphate;
hexitol phosphate		Escherichia coli metabolite;
human metabolite
triiodothyronine[no description available]low00tetrahydrothiophenes;
thiolactone		human metabolite
kinetensin[no description available]low00oligopeptidehistamine releasing agent;
human metabolite
estra-1(10),4-diene-2,3,17-trione[no description available]low0017-oxo steroid;
3-oxo-Delta(4) steroid;
orthoquinones		human metabolite
2'-deoxycytidine diphosphate[no description available]low002'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-diphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
n-methylserotonin[no description available]low00phenols;
tryptamines		human metabolite;
plant metabolite
gamma-glutamylglutamine[no description available]low00dipeptidehuman metabolite
3,4-dihydroxybutanoic acid[no description available]low003-hydroxy fatty acid;
omega-hydroxy-short-chain fatty acid		human metabolite
n-palmitoylglycine[no description available]low00fatty amide;
N-acylglycine 16:0		human metabolite;
marine metabolite
gamma-glutamyl-leucine[no description available]low00glutamyl-L-amino acidhuman metabolite
ribulose[no description available]low00ribuloseEscherichia coli metabolite;
human metabolite
3,4-dihydroxyphenylglycolaldehyde[no description available]low00catechols;
hydroxyaldehyde		human metabolite;
mouse metabolite;
neurotoxin
androsterone sulfate[no description available]low0017-oxo steroid;
androstanoid;
steroid sulfate		human metabolite;
mouse metabolite
3,7,12-trihydroxycoprostane[no description available]low0012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid		human metabolite;
mouse metabolite
saccharopine[no description available]low00amino acid opine;
L-lysine derivative		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
allysine[no description available]low00allysine;
amino acid zwitterion;
aminoadipate semialdehyde;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
orotidylic acid[no description available]low00pyrimidine ribonucleoside 5'-monophosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
allocholic acid[no description available]low0012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
allo-bile acid;
C24-steroid		human metabolite;
marine metabolite;
rat metabolite
beta-ureidoisobutyric acid[no description available]low00ureidocarboxylic acidhuman metabolite;
mouse metabolite
kynurenine[no description available]low00amino acid zwitterion;
kynurenine;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
nicotinate ribonucleoside[no description available]low00ammonium betainehuman metabolite
n(6)-(n-threonylcarbonyl)adenosine[no description available]low00L-threonine derivative;
N-(adenosin-N(6)-ylcarbonyl)threonine		Escherichia coli metabolite;
human metabolite
sedoheptulose 7-phosphate[no description available]low00ketoheptose phosphate;
sedoheptulose derivative		Escherichia coli metabolite;
human metabolite;
mouse metabolite
histidinol[no description available]low00amino alcohol;
imidazoles		EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
thiocysteine[no description available]low00amino acid zwitterion;
S-substituted L-cysteine		human metabolite;
mouse metabolite
nicotinic acid adenine dinucleotide[no description available]low00nicotinic acid dinucleotideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol[no description available]low003beta-sterolhuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
bradykinin, des-phe(8)-des-arg(9)-[no description available]low00oligopeptidehuman metabolite;
rat metabolite
isobutyryl-1-carnitine[no description available]low00methyl-branched fatty acyl-L-carnitine;
O-isobutyrylcarnitine;
saturated fatty acyl-L-carnitine		human metabolite
threitol[no description available]low00threitolhuman metabolite
biotin[no description available]low00biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
aceglutamide[no description available]low00N-acetyl-L-amino acid;
N(2)-acetylglutamine;
N(2)-acyl-L-glutamine		human metabolite
aflatoxin b1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
isospaglumic acid[no description available]low00dipeptidehuman metabolite
2'-deoxyadenosine triphosphate[no description available]low002'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-diphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
2-ethylhydracrylic acid[no description available]low00branched-chain saturated fatty acid;
hydroxy fatty acid;
short-chain fatty acid		human metabolite
2-methyl-3-oxovaleric acid[no description available]low003-oxo monocarboxylic acidhuman metabolite
monoacetylcadaverine[no description available]low00acetamides;
N-substituted cadaverine;
primary amino compound;
secondary carboxamide		human metabolite
beta-citrylglutamic acid[no description available]low00N-acyl-L-glutamic acid;
tetracarboxylic acid		human metabolite;
iron chelator
maltotriose[no description available]low00maltotriose trisaccharidehuman metabolite
cholestane-3,7,12,26-tetrol[no description available]low0012alpha-hydroxy steroid;
26-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid		human metabolite;
mouse metabolite
beta-leucine[no description available]low00beta-amino acidhuman metabolite
2-methylbutyrylglycine[no description available]low00N-acylglycinehuman metabolite
neurotensin (1-8)[no description available]low00peptide zwitterion;
peptide		human metabolite
erythritol[no description available]low00butane-1,2,3,4-tetrolantioxidant;
human metabolite;
plant metabolite
cortisone[no description available]low0011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
5 alpha-androstane-3 beta,17 beta-diol[no description available]low0017beta-hydroxy steroid;
3beta-hydroxy steroid;
androstane-3,17-diol		Daphnia magna metabolite;
human metabolite
cholesteryl palmitate[no description available]low00cholesteryl esterhuman metabolite;
mouse metabolite
lanosterol[no description available]low0014alpha-methyl steroid;
3beta-sterol;
tetracyclic triterpenoid		bacterial metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
2-hydroxyestradiol[no description available]low0017beta-hydroxy steroid;
2-hydroxy steroid		carcinogenic agent;
human metabolite;
metabolite;
mouse metabolite;
prodrug
5-hydroxyisourate[no description available]low00oxopurinehuman metabolite;
mouse metabolite
5-formyluracil[no description available]low00aldehyde;
nucleobase analogue;
pyrimidone		human metabolite;
mutagen
taurochenodeoxycholic acid[no description available]low00bile acid taurine conjugatehuman metabolite;
mouse metabolite
5'-methylthioadenosine[no description available]low00thioadenosinealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
5'-deoxyadenosine[no description available]low005'-deoxyribonucleoside;
adenosines		Escherichia coli metabolite;
human metabolite;
mouse metabolite
isomaltose[no description available]low00glycosylglucosehuman metabolite;
metabolite;
mouse metabolite
n-acetylneuraminic acid[no description available]low00N-acetylneuraminic acidsantioxidant;
bacterial metabolite;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
human metabolite;
mouse metabolite
glucosamine 6-phosphate[no description available]low002-amino-2-deoxy-D-glucopyranose 6-phosphatehuman metabolite;
Saccharomyces cerevisiae metabolite
carnosine[no description available]low00amino acid zwitterion;
dipeptide		anticonvulsant;
antineoplastic agent;
antioxidant;
Daphnia magna metabolite;
geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent
5-hydroxytryptophan[no description available]low005-hydroxytryptophan;
amino acid zwitterion;
hydroxy-L-tryptophan;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
plant metabolite
dopaquinone[no description available]low001,2-benzoquinones;
amino acid zwitterion;
L-phenylalanine derivative		human metabolite;
mouse metabolite
pantetheine[no description available]low00pantetheines;
thiol		human metabolite;
metabolite;
mouse metabolite
tryptophanamide[no description available]low00amino acid amide;
tryptophan derivative		human metabolite
5-diphosphomevalonic acid[no description available]low00carboxyalkyl phosphatehuman metabolite;
mouse metabolite
7-dehydrocholesterol[no description available]low003beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid;
Delta(5),Delta(7)-sterol		human metabolite;
mouse metabolite
cysteinylglycine[no description available]low00dipeptide zwitterion;
dipeptide		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
desmosterol[no description available]low003beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
C27-steroid;
cholestanoid		human metabolite;
mouse metabolite
monoiodotyrosine[no description available]low00amino acid zwitterion;
L-tyrosine derivative;
monoiodotyrosine;
non-proteinogenic L-alpha-amino acid		EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
human metabolite;
mouse metabolite
taurolithocholic acid[no description available]low00bile acid taurine conjugate;
monocarboxylic acid amide		human metabolite
n'-formylkynurenine[no description available]low00amino acid zwitterion;
N-formylkynurenine;
non-proteinogenic amino acid derivative;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
fuculose 1-phosphate[no description available]low00deoxyaldohexose phosphatehuman metabolite
nicotinamide-beta-riboside[no description available]low00N-glycosylnicotinamide;
pyridine nucleoside		geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
4-hydroxyphenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite
trimethyllysine[no description available]low00alpha-amino-acid cationhuman metabolite;
mouse metabolite
inositol 3,4-bisphosphate[no description available]low00myo-inositol bisphosphatehuman metabolite;
mouse metabolite
n-acetylglucosamine-1-phosphate[no description available]low00N-acetyl-D-glucosamine 1-phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
24,25-dihydrolanosterol[no description available]low003beta-sterol;
tetracyclic triterpenoid		human metabolite;
mouse metabolite
2-hydroxyestrone[no description available]low002-hydroxy steroid;
catechols		human metabolite
2-methoxyestrone[no description available]low0017-oxo steroid;
3-hydroxy steroid;
alicyclic ketone;
aromatic ether;
phenolic steroid;
phenols		human metabolite;
mouse metabolite
cortodoxone[no description available]low00deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
estradiol-3-glucuronide[no description available]low0017beta-hydroxy steroid;
beta-D-glucosiduronic acid;
steroid glucosiduronic acid		human metabolite;
mouse metabolite
acetyl adenylate[no description available]low005'-acylphosphoadenosinhuman metabolite;
mouse metabolite
epiandrosterone[no description available]low0017-oxo steroid;
3beta-hydroxy steroid;
androstanoid		androgen;
human metabolite
4,4-dimethylcholesta-8,14,24-trienol[no description available]low003beta-sterol;
Delta(14) steroid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
enkephalin, methionine[no description available]low00pentapeptide;
peptide zwitterion		analgesic;
antineoplastic agent;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist
7-ketolithocholic acid[no description available]low003alpha-hydroxy steroid;
bile acid;
monohydroxy-5beta-cholanic acid;
oxo-5beta-cholanic acid		human metabolite
dephosphocoenzyme a[no description available]low00adenosine 5'-phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
tretinoin[no description available]low00retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
3-hydroxy-3-methylglutaryl-coenzyme a[no description available]low003-hydroxy-3-methylglutaryl-CoA;
3-hydroxy fatty acyl-CoA		human metabolite;
mouse metabolite
retinol[no description available]low00retinol;
vitamin A		human metabolite;
mouse metabolite;
plant metabolite
ribothymidine[no description available]low00methyluridineantigen;
Escherichia coli metabolite;
human metabolite
docosahexaenoate[no description available]low00docosahexaenoic acid;
omega-3 fatty acid		algal metabolite;
antineoplastic agent;
Daphnia tenebrosa metabolite;
human metabolite;
mouse metabolite;
nutraceutical
hexanoyl-coenzyme a[no description available]low00medium-chain fatty acyl-CoAEscherichia coli metabolite;
human metabolite;
mouse metabolite
tyrosine o-sulfate[no description available]low00aryl sulfate;
L-tyrosine derivative;
O-sulfoamino acid		human metabolite
retinaldehyde[no description available]low00retinal;
vitamin A		gap junctional intercellular communication inhibitor;
human metabolite;
mouse metabolite
squalene[no description available]low00triterpenehuman metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
thyrotropin-releasing hormone[no description available]low00peptide hormone;
tripeptide		human metabolite
n-methylproline[no description available]low00L-alpha-amino acid zwitterion;
L-proline derivative;
tertiary amino compound		human metabolite;
plant metabolite
citraconic acid[no description available]low00dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
flavin-adenine dinucleotide[no description available]low00flavin adenine dinucleotide;
vitamin B2		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prosthetic group
flavin mononucleotide[no description available]low00flavin mononucleotide;
vitamin B2		bacterial metabolite;
coenzyme;
cofactor;
human metabolite;
mouse metabolite
mannose 1-phosphate[no description available]low00mannose phosphatefundamental metabolite;
human metabolite
glycerylphosphorylcholine[no description available]low00phosphocholines;
sn-glycerol 3-phosphates		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neuroprotective agent;
parasympatholytic;
Saccharomyces cerevisiae metabolite
urocanic acid[no description available]low00urocanic acidhuman metabolite
cysteine sulfinic acid[no description available]low00organosulfinic acid;
S-substituted L-cysteine		Escherichia coli metabolite;
human metabolite;
metabotropic glutamate receptor agonist;
mouse metabolite
cholesterol acetate[no description available]low00acetate ester;
cholesteryl ester		human metabolite
1,6-anhydro-beta-glucopyranose[no description available]low00anhydrohexoseArabidopsis thaliana metabolite;
biomarker;
human metabolite
glycylvaline[no description available]low00dipeptidehuman metabolite
sodium taurodeoxycholate[no description available]low00bile acid taurine conjugatehuman metabolite
estrone sulfate[no description available]low0017-oxo steroid;
steroid sulfate		human metabolite;
mouse metabolite
hydroxylysine[no description available]low005-hydroxylysine;
hydroxy-L-lysine		human metabolite
glycodeoxycholic acid[no description available]low00bile acid glycine conjugatehuman metabolite
isobutyryl-coenzyme a[no description available]low00methyl-branched fatty acyl-CoA;
short-chain fatty acyl-CoA		human metabolite;
mouse metabolite
galactaric acid[no description available]low00hexaric acidhuman metabolite
dihydroxycoprostane[no description available]low003alpha-hydroxy steroid;
7alpha-hydroxy steroid		human metabolite;
mouse metabolite
angiotensin i, ile(5)-[no description available]low00angiotensin;
peptide zwitterion		human metabolite;
neurotransmitter agent
fructosyl-glycine[no description available]low00fructosamine;
glycine derivative;
glyco-amino acid		human metabolite
arachidoyl-coenzyme a[no description available]low0011,12-saturated fatty acyl-CoA;
long-chain fatty acyl-CoA		human metabolite
lignoceroyl-coenzyme a[no description available]low00very long-chain fatty acyl-CoAhuman metabolite;
Saccharomyces cerevisiae metabolite
5-hydroxybenzimidazole[no description available]low00benzimidazoles;
phenols		bacterial metabolite;
human metabolite;
rat metabolite
n-carbamylglutamate[no description available]low00glutamic acid derivative;
ureas		human metabolite
citramalate[no description available]low00dicarboxylic acid dianionhuman metabolite;
plant metabolite
4-cresol sulfate[no description available]low00aryl sulfategut flora metabolite;
human metabolite;
uremic toxin
sphingosine[no description available]low00sphing-4-eninehuman metabolite;
mouse metabolite
bilirubin[no description available]low00biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
leukotriene a4[no description available]low00epoxy fatty acid;
leukotriene;
long-chain fatty acid;
oxylipin;
polyunsaturated fatty acid		human metabolite;
mouse metabolite;
plant metabolite
prostaglandin b1[no description available]low00prostaglandins Bhuman metabolite
calcitriol[no description available]low00D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical
psychosine[no description available]low00glycosylsphingoidhuman metabolite
ubiquinone 9[no description available]low00ubiquinonesantioxidant;
human metabolite
beta carotene[no description available]low00carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A
11-cis-retinal[no description available]low00retinalchromophore;
human metabolite;
mouse metabolite
leukotriene b4[no description available]low00dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid		human metabolite;
mouse metabolite;
plant metabolite;
vasoconstrictor agent
leukotriene c4[no description available]low00leukotrienebronchoconstrictor agent;
human metabolite;
mouse metabolite
prostaglandin f2beta[no description available]low00prostaglandins Fbetahuman metabolite
8,11,14-eicosatrienoic acid[no description available]low00fatty acid 20:3;
long-chain fatty acid		fungal metabolite;
human metabolite;
nutraceutical
15-keto-5,8,11,13-eicosatetraenoic acid[no description available]low00oxoicosatetraenoic acidhuman metabolite
15-hydroxy-5,8,11,13-eicosatetraenoic acid[no description available]low00(5Z,8Z,11Z,13E)-15-HETEhuman metabolite;
mouse metabolite
5-hydroxy-6,8,11,14-eicosatetraenoic acid[no description available]low00HETEhuman metabolite;
mouse metabolite
cholecalciferol[no description available]low00D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol;
steroid hormone		geroprotector;
human metabolite
leukotriene d4[no description available]low00dipeptide;
leukotriene;
organic sulfide		bronchoconstrictor agent;
human metabolite;
mouse metabolite
prostaglandin a2[no description available]low00prostaglandins Ahuman metabolite
prostaglandin b2[no description available]low00prostaglandins Bhuman metabolite
prostaglandin g2[no description available]low00prostaglandins Ghuman metabolite;
mouse metabolite
9-deoxy-delta-9-prostaglandin d2[no description available]low00prostaglandins Jhuman metabolite
11-dehydro-thromboxane b2[no description available]low00thromboxanehuman metabolite
lipoxin a4[no description available]low00hydroxy polyunsaturated fatty acid;
lipoxin;
long-chain fatty acid		human metabolite;
metabolite
gamma-linolenic acid[no description available]low00linolenic acid;
omega-6 fatty acid		human metabolite;
mouse metabolite;
plant metabolite
prostaglandin e3[no description available]low00prostaglandins Ehuman metabolite
leukotriene f-4[no description available]low00dipeptide;
leukotriene;
organic sulfide		human metabolite
prostaglandin f1[no description available]low00prostaglandins Falphahuman metabolite
previtamin d(3)[no description available]low00D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol		human metabolite
brassicasterol[no description available]low003beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		algal metabolite;
animal metabolite;
biomarker;
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor;
human metabolite;
marine metabolite;
plant metabolite;
sterol biosynthesis inhibitor
retinoyl beta-glucuronide[no description available]low00glucuronic acids;
retinoid		human metabolite
coenzyme q10[no description available]low00ubiquinonesantioxidant;
ferroptosis inhibitor;
human metabolite
prostaglandin d3[no description available]low00prostaglandins Dhuman metabolite
glyceryl 2-arachidonate[no description available]low002-acylglycerol 20:4;
endocannabinoid		human metabolite
tocotrienol, alpha[no description available]low00tocotrienol;
vitamin E		ferroptosis inhibitor;
human metabolite;
neuroprotective agent;
plant metabolite
11-ketotestosterone[no description available]low0011-oxo steroid;
17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
human metabolite;
marine xenobiotic metabolite
menatetrenone[no description available]low00menaquinoneanti-inflammatory agent;
antioxidant;
bone density conservation agent;
human metabolite;
neuroprotective agent
phthioic acid[no description available]low00branched-chain saturated fatty acid;
fatty acid 26:0;
methyl-branched fatty acid;
very long-chain fatty acid		Aspergillus metabolite;
human metabolite
2-decenoic acid[no description available]low002-decenoic acidhuman metabolite
9,11-linoleic acid[no description available]low00octadeca-9,11-dienoic acidanti-inflammatory agent;
antiatherogenic agent;
antineoplastic agent;
apoptosis inducer;
bacterial xenobiotic metabolite;
human metabolite
9-hydroxy-10,12-octadecadienoic acid[no description available]low00HODE;
octadecadienoic acid		human metabolite;
metabolite;
mouse metabolite;
plant metabolite
17-phenyltrinorprostaglandin e2[no description available]low00alicyclic ketone;
beta-hydroxy ketone;
hydroxy monocarboxylic acid;
olefinic compound;
oxo monocarboxylic acid;
prostanoid;
secondary alcohol		human metabolite;
prostaglandin receptor agonist
thromboxane b3[no description available]low00thromboxanes Bhuman metabolite;
mouse metabolite
12-hydroxy-5,8,10,14-eicosatetraenoic acid[no description available]low00(5Z,8Z,10E,14Z)-12-hydroxyicosatetraenoic acid;
HETE		human metabolite;
pro-angiogenic agent
20-hydroxy-5,8,11,14-eicosatetraenoic acid[no description available]low00HETE;
hydroxy monocarboxylic acid		human metabolite;
mouse metabolite
5-oxo-6,8,11,14-eicosatetraenoic acid[no description available]low00oxoicosatetraenoic acidhuman metabolite;
immunomodulator;
mouse metabolite
8-isoprostaglandin e2[no description available]low00cyclic ketone;
diol;
prostanoid;
secondary alcohol		bronchoconstrictor agent;
human metabolite;
rat metabolite;
vasoconstrictor agent
oleylamide[no description available]low00primary fatty amidehuman metabolite;
plant metabolite
monolinolein[no description available]low001-acylglycerol 18:2;
rac-1-monoacylglycerol		antiviral agent;
human metabolite;
plant metabolite
1,25-dihydroxy-24-oxo-vitamin d3[no description available]low00hydroxycalciol;
oxocalciol;
tertiary alpha-hydroxy ketone		human metabolite
calcifediol[no description available]low00D3 vitamins;
diol;
hydroxycalciol		bone density conservation agent;
human metabolite;
metabolite;
mouse metabolite;
nutraceutical
hyodeoxycholic acid[no description available]low005beta-cholanic acids;
6alpha,20xi-murideoxycholic acid;
bile acid;
C24-steroid		human metabolite;
mouse metabolite
vitamin k 1[no description available]low00phylloquinones;
vitamin K		cofactor;
human metabolite;
plant metabolite
cerium[no description available]low00CE(18:2);
cholesteryl octadeca-9,12-dienoate		human metabolite;
mouse metabolite
xylulose[no description available]low00xyluloseEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
11-dehydrocorticosterone[no description available]low0011-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
corticosteroid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
1-butyl oleate[no description available]low00fatty acid esterhuman metabolite
8-hydroxyadenine[no description available]low006-aminopurines;
heteroaryl hydroxy compound;
nucleobase analogue;
oxopurine		bacterial metabolite;
human metabolite
erucyl amide[no description available]low0013-docosenamideEC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite;
mammalian metabolite;
plant metabolite;
rat metabolite
vitamin mk 8[no description available]low00menaquinoneEscherichia coli metabolite;
human metabolite
2,3-oxidosqualene[no description available]low002,3-epoxysqualenehuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2-keto-4-hydroxyglutarate[no description available]low00oxo dicarboxylatehuman metabolite;
Saccharomyces cerevisiae metabolite
deoxyribose[no description available]low00deoxypentosehuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
iditol[no description available]low00iditolfungal metabolite;
human metabolite
glutamate[no description available]low00glutamate(1-);
polar amino acid zwitterion		EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor;
human metabolite;
Saccharomyces cerevisiae metabolite
fumarates[no description available]low00butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite
cerotate[no description available]low00fatty acid anion 26:0;
omega-methyl fatty acid anion;
very long-chain fatty acid anion		human metabolite;
Saccharomyces cerevisiae metabolite
adenosine triphosphate[no description available]low00nucleoside 5'-triphoshate(4-)cofactor;
fundamental metabolite;
human metabolite
docosapentaenoic acid[no description available]low00docosapentaenoic acid;
omega-3 fatty acid		algal metabolite;
human metabolite
3-methylbutyrylcarnitine[no description available]low00C5-acylcarnitinehuman metabolite
hexanoylcarnitine[no description available]low00hexanoate ester;
O-acylcarnitine		human metabolite
linoleamide[no description available]low00primary fatty amidehuman metabolite
13-cis-retinal[no description available]low00retinalhuman metabolite
4-hydroxyretinoic acid[no description available]low00retinoid;
secondary allylic alcohol		human metabolite
4-oxo-2-nonenal[no description available]low00enal;
enone		human metabolite
20,22-dihydroxycholesterol[no description available]low0020-hydroxy steroid;
22-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid;
oxysterol		human metabolite;
mouse metabolite
biotinate[no description available]low00monocarboxylic acid anion;
vitamin B7		cofactor;
human metabolite;
Saccharomyces cerevisiae metabolite
6 beta-hydroxycortisol[no description available]low0011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
6beta-hydroxy steroid;
C21-steroid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mammalian metabolite;
probe
fuculose[no description available]low00deoxyketohexoseEscherichia coli metabolite;
human metabolite
gamma-glutamylvaline[no description available]low00glutamyl-L-amino acidhuman metabolite
ophthalmic acid[no description available]low00L-glutamine derivativebiomarker;
human metabolite
acetylcarnitine[no description available]low00O-acetylcarnitine;
saturated fatty acyl-L-carnitine		human metabolite;
Saccharomyces cerevisiae metabolite
adenosine diphosphate[no description available]low00nucleoside 5'-diphosphate(3-)fundamental metabolite;
human metabolite
cyclic amp[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
1,23,25-trihydroxyvitamin d3[no description available]low00D3 vitamins;
hydroxy seco-steroid;
hydroxycalciol;
tetrol		human metabolite
phosphocreatine[no description available]low00phosphagen;
phosphoamino acid		human metabolite;
mouse metabolite
ursodoxicoltaurine[no description available]low00bile acid taurine conjugateanti-inflammatory agent;
apoptosis inhibitor;
bone density conservation agent;
cardioprotective agent;
human metabolite;
neuroprotective agent
arachidonoylserotonin[no description available]low00N-acylserotonin;
phenols		anti-inflammatory agent;
anticonvulsant;
antioxidant;
capsaicin receptor antagonist;
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor;
human metabolite;
signalling molecule
homocarnosine[no description available]low00dipeptide zwitterion;
dipeptide;
homocarnosine;
L-histidine derivative;
N-acyl-L-alpha-amino acid anion;
N-acyl-L-alpha-amino acid		human metabolite
3-hydroxyproline[no description available]low003-hydroxyproline;
amino acid zwitterion;
D-proline derivative		bacterial metabolite;
human metabolite
octanoylcarnitine[no description available]low00O-octanoylcarnitine;
saturated fatty acyl-L-carnitine		human metabolite
palmitoylcarnitine[no description available]low00O-palmitoylcarnitine;
saturated fatty acyl-L-carnitine		EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
human metabolite;
mouse metabolite
cyclic 3',5'-thymidine monophosphate[no description available]low003',5'-cyclic pyrimidine nucleotidehuman metabolite
pristanal[no description available]low002-methyl-branched fatty aldehyde;
saturated fatty aldehyde		human metabolite
lanosten-3-ol-32-al[no description available]low0014alpha-formyl steroid;
3beta-sterol;
tetracyclic triterpenoid		human metabolite
thiamine pyrophosphate[no description available]low00organophosphate oxoanion;
vitamin B1		human metabolite;
Saccharomyces cerevisiae metabolite
adenosine monophosphate[no description available]low00nucleoside 5'-monophosphate(2-)cofactor;
fundamental metabolite;
human metabolite
nad[no description available]low00organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
cob(ii)alamin[no description available]low00cobalamincofactor;
human metabolite
nociceptin[no description available]low00organic molecular entity;
polypeptide		human metabolite;
rat metabolite
3-hydroxy-3-methyl-hexanoic acid[no description available]low003-hydroxy monocarboxylic acid;
volatile organic compound		human metabolite
uridine diphosphate[no description available]low00nucleoside 5'-diphosphate(3-)human metabolite;
Saccharomyces cerevisiae metabolite
n-acetylgalactosamine-1-phosphate[no description available]low00D-galactosamine 1-phosphatehuman metabolite
1-phospho-5-s-methylthioribulose[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
s-adenosylmethionine[no description available]low00organic cation;
sulfonium compound		coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
10-nitro-oleic acid[no description available]low00long-chain fatty acid;
monounsaturated fatty acid;
nitro fatty acid		human metabolite
ticrynafen[no description available]low00monocarboxylic acid anion;
organophosphate oxoanion		human metabolite
s-(1,2-dicarboxyethyl)cysteine[no description available]low00L-cysteine thioether;
tricarboxylic acid		human metabolite;
Maillard reaction product
apelin-13 peptide[no description available]low00oligopeptideantihypertensive agent;
autophagy inhibitor;
biomarker;
human metabolite;
neuroprotective agent
p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe[no description available]low00polypeptideapoptosis inhibitor;
human metabolite;
neuroprotective agent
taurolithocholic acid 3-sulfate[no description available]low00steroid sulfate oxoanionhuman metabolite
inositol 1,3,4-trisphosphate[no description available]low00inositol phosphate oxoanionhuman metabolite
diadenosine tetraphosphate[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
2-ketoarginine[no description available]low002-oxo monocarboxylic acid;
zwitterion		human metabolite;
mouse metabolite
adenosine diphosphate glucose[no description available]low00NDP-alpha-D-glucose(2-);
ribonucleoside 5'-diphosphate-alpha-D-glucose(2-)		human metabolite
nicotinate mononucleotide[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
oleoylcarnitine[no description available]low00monounsaturated fatty acyl-L-carnitineglycine transporter 2 inhibitor;
human metabolite
uridine diphosphate n-acetylgalactosamine[no description available]low00nucleotide-sugar oxoanionhuman metabolite
6-phosphogluconolactone[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
3-hydroxyisovalerylcarnitine[no description available]low00O-acylcarnitinehuman metabolite
angiotensin i[no description available]low00angiotensin;
peptide zwitterion		antihypertensive agent;
cardioprotective agent;
human metabolite;
rat metabolite
9-PAHSA[no description available]low00FAHFA;
long-chain fatty acid		anti-inflammatory agent;
human metabolite;
hypoglycemic agent
lugdunin[no description available]low00homodetic cyclic peptide;
indoles;
macrocycle;
peptide antibiotic;
thiazolidines		human metabolite;
rat metabolite
deoxyguanosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyinosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
deoxyguanosine triphosphate[no description available]low00deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
7,8-dihydroneopterin[no description available]low00dihydropterin;
neopterins		Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyinosine monophosphate[no description available]low00deoxyinosine phosphate;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
guanosine diphosphate mannose[no description available]low00GDP-D-mannoseEscherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
guanine[no description available]low002-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
inosinic acid[no description available]low00inosine phosphate;
purine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
inosine triphosphate[no description available]low00inosine phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
sapropterin[no description available]low005,6,7,8-tetrahydrobiopterincoenzyme;
cofactor;
diagnostic agent;
human metabolite
folic acid[no description available]low00folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
dyspropterin[no description available]low00biopterins;
tetrahydropterin		human metabolite;
metabolite;
mouse metabolite
8-nitroguanosine 3',5'-cyclic monophosphate[no description available]low003',5'-cyclic purine nucleotide;
C-nitro compound		biomarker;
Brassica napus metabolite;
human metabolite;
signalling molecule
n(2),n(2)-dimethylguanosine[no description available]low00methylguanosinehuman metabolite
creatinine[no description available]low00imidazolidinone;
lactam		diagnostic agent;
human metabolite
apelin-12 peptide[no description available]low00oligopeptidebiomarker;
human blood serum metabolite;
human metabolite;
neuroprotective agent
goralatide[no description available]low00oligopeptide;
tetrapeptide		anti-inflammatory agent;
pro-angiogenic agent
hc toxin[no description available]low00homodetic cyclic peptide;
tetrapeptide		antineoplastic agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
metabolite;
phytotoxin
acetyl-aspartyl-glutamyl-valyl-aspartal[no description available]low00tetrapeptideprotease inhibitor
coelichelin[no description available]low00formamides;
hydroxamic acid;
tetrapeptide		bacterial metabolite;
siderophore
soblidotin[no description available]low00tetrapeptideantineoplastic agent;
apoptosis inducer;
microtubule-destabilising agent
dolastatin 10[no description available]low001,3-thiazoles;
tetrapeptide		animal metabolite;
antineoplastic agent;
apoptosis inducer;
marine metabolite;
microtubule-destabilising agent
phenylalanyl-glycyl-leucyl-methioninamide[no description available]low00tetrapeptide
succinyl-leucyl-leucyl-valyl-tyrosyl-methylcoumarinamide[no description available]low007-aminocoumarins;
tetrapeptide		fluorochrome
carfilzomib[no description available]low00epoxide;
morpholines;
tetrapeptide		antineoplastic agent;
proteasome inhibitor
mastoparan[no description available]low00mastoparans;
peptidyl amide		antimicrobial agent
forapin[no description available]low00peptidyl amide;
polypeptide		animal metabolite;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.13 (protein kinase C) inhibitor;
hepatoprotective agent;
neuroprotective agent;
venom
mastoparan x[no description available]low00mastoparans;
peptidyl amide		antibacterial agent
ConditionIndicatedRelationship StrengthStudiesTrials
Aberrant Tissue0low10
Ache0medium41
Acute Confusional Senile Dementia0low10
Acute Edematous Pancreatitis0low10
Acute Pancreatitis0low10
Acute Post-Traumatic Stress Disorder0medium21
Adenocarcinoma0low60
Adenocarcinoma, Basal Cell0low60
Adenocarcinoma, Granular Cell0low60
Adenocarcinoma, Oxyphilic0low60
Adenocarcinoma, Tubular0low60
Adenoma0low10
Adenoma, Basal Cell0low10
Adenoma, Follicular0low10
Adenoma, Malignant0low60
Adenoma, Microcystic0low10
Adenoma, Monomorphic0low10
Adenoma, Papillary0low10
Adenoma, Trabecular0low10
Aging0medium31
Agoraphobia0medium32
Alcohol Drinking0low20
Allodynia0low10
Allodynia, Mechanical0low10
Allodynia, Tactile0low10
Allodynia, Thermal0low10
Alzheimer Dementia0low10
Alzheimer Disease0low10
Alzheimer Disease, Early Onset0low10
Alzheimer Disease, Late Onset0low10
Alzheimer Sclerosis0low10
Alzheimer Syndrome0low10
Alzheimer Type Senile Dementia0low10
Alzheimer-Type Dementia (ATD)0low10
Alzheimer's Disease0low10
Alzheimer's Disease, Focal Onset0low10
Alzheimer's Diseases0low10
Anankastic Personality0medium11
Anochlesia0low10
Anorexia0low20
Anxiety0medium4011
Anxiety Disorders0medium156
Anxiety Neuroses0medium156
Anxiety States, Neurotic0medium156
Anxiety, Separation0low10
As If Personality0low10
Atrophy0low30
Autoimmune Diabetes0low10
Autosomal Dominant Cerebellar Ataxia, Type II0low10
Avoidant Personality Disorder0low10
Behavior Disorders0low10
Bile Duct Obstruction0low10
Biliary Stasis0low10
Blood Pressure, High0medium21
Body Weight0low40
Bradyarrhythmia0low10
Bradyarrhythmias0low10
Bradycardia0low10
Bradykinesia0low10
Brain Ischemia0low10
Briquet Syndrome0medium11
Cancer of Colon0low40
Cancer of Intestines0low10
Cancer of Pancreas0low40
Cancer of Pituitary0low10
Cancer of Stomach0low60
Cancer of the Colon0low40
Cancer of the Intestines0low10
Cancer of the Pancreas0low40
Cancer of the Pituitary0low10
Cancer of the Stomach0low60
Cancer of the Thyroid0low30
Cancer of Thyroid0low30
Carcinoma0low30
Carcinoma, Anaplastic0low30
Carcinoma, Cribriform0low60
Carcinoma, Granular Cell0low60
Carcinoma, Spindle-Cell0low30
Carcinoma, Tubular0low60
Carcinoma, Undifferentiated0low30
Carcinomatosis0low30
Catalepsy0low10
Cataract0low10
Cataract, Membranous0low10
Central Hypothyroidism0low10
Cerea Flexibilitas0low10
Cerebellar Degeneration with Slow Eye Movements0low10
Cerebelloparenchymal Disorder I0low10
Cerebral Ischemia0low10
Cholera Infantum0low10
Cholestasis0low10
Choristoma0low10
Chronic Disease0low10
Chronic Illness0low10
Chronic Post-Traumatic Stress Disorder0medium21
Chronically Ill0low10
Claustrophobia0medium11
Cocarcinogenesis0low10
Cognition Disorders0medium22
Colon Cancer0low40
Colon Neoplasms0low40
Colonic Cancer0low40
Colonic Neoplasms0low40
Condition, Preneoplastic0low20
Conditions, Preneoplastic0low20
Curling Ulcer0low170
Curling's Ulcer0low170
Decerebrate Posturing0low10
Decerebrate State0low10
Decorticate Rigidity0low10
Decorticate State0low10
Delayed Onset Post-Traumatic Stress Disorder0medium21
Dementia Praecox0low10
Dementia, Alzheimer Type0low10
Dementia, Presenile0low10
Dementia, Primary Senile Degenerative0low10
Dementia, Senile0low10
Depression0low40
Depression, Endogenous0low20
Depression, Involutional0medium11
Depression, Neurotic0low20
Depression, Unipolar0low20
Depressive Disorder0low20
Depressive Disorder, Major0medium11
Depressive Syndrome0low20
Diabetes Mellitus, Brittle0low10
Diabetes Mellitus, Insulin-Dependent0low10
Diabetes Mellitus, Insulin-Dependent, 10low10
Diabetes Mellitus, Juvenile-Onset0low10
Diabetes Mellitus, Ketosis-Prone0low10
Diabetes Mellitus, Sudden-Onset0low10
Diabetes Mellitus, Type 10low10
Diabetes Mellitus, Type I0low10
Diabetes, Autoimmune0low10
Diagnosis, Psychiatric0low10
Disease Models, Animal0low100
Dominantly-Inherited Spinocerebellar Ataxias0low10
Drug Withdrawal Symptoms0medium41
Duodenal Ulcer0low170
Early Onset Alzheimer Disease0low10
Ectopic Tissue0low10
Encephalopathy, Ischemic0low10
Epithelial Neoplasms, Malignant0low30
Epithelial Tumors, Malignant0low30
Epithelioma0low30
Esophageal Diseases0low10
Experimental Neoplasms0low10
Familial Alzheimer Disease (FAD)0low10
Fistula0low10
Flexibility, Waxy0low10
Focal Onset Alzheimer's Disease0low10
Functional Gastrointestinal Disorders0low10
Gastric Cancer0low60
Gastric Cancer, Familial Diffuse0low60
Gastric Diseases0low20
Gastric Fistula0low40
Gastric Neoplasms0low60
Gastric Ulcer0low130
Gastritis0low10
Gastritis, Atrophic0low10
Gastroduodenal Ulcer0low40
Gastrointestinal Diseases0low10
Gastrointestinal Disorders0low10
Gastrointestinal Disorders, Functional0low10
Genetic Predisposition0low20
Genetic Predisposition to Disease0low20
Genetic Susceptibility0low20
Helicobacter Infections0low10
Hemorrhage, Peptic Ulcer0low10
Hemorrhagic Shock0low10
Heterotopic Tissue0low10
Hyperactivity, Motor0low10
Hyperalgesia0low10
Hyperalgesia, Mechanical0low10
Hyperalgesia, Primary0low10
Hyperalgesia, Secondary0low10
Hyperalgesia, Tactile0low10
Hyperalgesia, Thermal0low10
Hyperalgesic Sensations0low10
Hyperalgia0low10
Hyperalgia, Mechanical0low10
Hyperalgia, Primary0low10
Hyperalgia, Secondary0low10
Hyperkinesia0low10
Hyperkinesia, Generalized0low10
Hyperkinesis0low10
Hyperkinetic Movements0low10
Hyperplasia0low20
Hypertension0medium21
Hypodynamia0low10
Hypokinesia0low10
Hypokinesia, Antiorthostatic0low10
Hypothyroidism0low10
IDDM0low10
Impulse-Ridden Personality0low10
Inadequate Personality0low10
Infections, Helicobacter0low10
Inflammation0low10
Innate Inflammatory Response0low10
Insulin-Dependent Diabetes Mellitus 10low10
Intestinal Cancer0low10
Intestinal Diseases0low10
Intestinal Neoplasms0low10
Intestines Cancer0low10
Intestines Neoplasms0low10
Ischemia, Cerebral0low10
Ischemic Encephalopathy0low10
Juvenile-Onset Diabetes0low10
Late Onset Alzheimer Disease0low10
Lens Opacities0low10
Major Depressive Disorder0medium11
Malignant Epithelial Neoplasms0low30
Marginal Ulcer0low40
Mechanical Allodynia0low10
Mechanical Hyperalgesia0low10
Medically Unexplained Syndrome0medium11
Medically Unexplained Syndromes0medium11
Melancholia0low20
Melancholia, Involutional0medium11
Mental Disorders0low10
Mental Disorders, Severe0low10
Mental Illness0low10
Menzel Type OPCA0low10
Metaplasia0low10
Metastase0low10
Metastases, Neoplasm0low10
Metastasis0low10
Metastasis, Neoplasm0low10
Moral Injury0medium21
Morphine Abuse0low10
Morphine Addiction0low10
Morphine Dependence0low10
Muscle Contraction0low160
Muscle Relaxation0low10
Narcissistic Personality Disorder0low10
Neoplasm Metastases0low10
Neoplasm Metastasis0low10
Neoplasms, Colonic0low40
Neoplasms, Experimental0low10
Neoplasms, Gastric0low60
Neoplasms, Intestinal0low10
Neoplasms, Malignant Epithelial0low30
Neoplasms, Pancreatic0low40
Neoplasms, Stomach0low60
Neoplasms, Thyroid0low30
Nerve Degeneration0low10
Neuron Degeneration0low10
Neuroses, Anxiety0medium156
Neuroses, Phobic0medium11
Neuroses, Post-Traumatic0medium21
Neuroses, Posttraumatic0medium21
Neurosis, Depressive0low20
Neurosis, Obsessive-Compulsive0medium11
Obsessive-Compulsive Disorder0medium11
Olivopontocerebellar Atrophy 20low10
Olivopontocerebellar Atrophy I0low10
Olivopontocerebellar Atrophy II0low10
Olivopontocerebellar Atrophy III0low10
Olivopontocerebellar Atrophy IV0low10
Olivopontocerebellar Atrophy, Holguin Type0low10
OPCA with Macular Degeneration and External Ophthalmoplegia0low10
OPCA with Retinal Degeneration0low10
Overinclusion0medium22
Pain0medium41
Pain Disorder0medium11
Pain, Burning0medium41
Pain, Crushing0medium41
Pain, Migratory0medium41
Pain, Radiating0medium41
Pain, Splitting0medium41
Pancreas Cancer0low40
Pancreas Neoplasms0low40
Pancreatic Cancer0low40
Pancreatic Neoplasms0low40
Pancreatic Parenchyma with Edema0low10
Pancreatic Parenchymal Edema0low10
Pancreatitis0low10
Pancreatitis, Acute0low10
Pancreatitis, Acute Edematous0low10
Panic Attacks0medium8345
Panic Disorder0medium8345
Paraphrenia, Involutional0medium11
Peptic Ulcer0low40
Peptic Ulcer Hemorrhage0low10
Peripancreatic Fat Necrosis0low10
Personality Disorders0low10
Phobia, School0medium11
Phobias0medium11
Phobic Disorders0medium11
Phobic Neuroses0medium11
Pituitary Adenoma0low10
Pituitary Cancer0low10
Pituitary Carcinoma0low10
Pituitary Neoplasms0low10
Pituitary Tumors0low10
Post Traumatic Stress Disorder0medium21
Post-Traumatic Stress Disorders0medium21
Posttraumatic Stress Disorders0medium21
Precancerous Conditions0low20
Predisposition, Genetic0low20
Pregnancy0low30
Premenstrual Syndrome0medium43
Premenstrual Tension0medium43
Preneoplastic Condition0low20
Preneoplastic Conditions0low20
Presenile Alzheimer Dementia0low10
Primary Hypothyroidism0low10
Primary Senile Degenerative Dementia0low10
Pseudoaphakia0low10
Psychiatric Diagnosis0low10
Psychiatric Diseases0low10
Psychiatric Disorders0low10
Psychiatric Illness0low10
Psychoses0low10
Psychosis0low10
Psychosis, Brief Reactive0low10
Psychosis, Involutional0medium11
Psychotic Disorders0low10
PTSD0medium21
Recrudescence0low50
Recurrence0low50
Relapse0low50
Rigidity, Decerebrate0low10
Rigidity, Decorticate0low10
Sarcoma0low10
Sarcoma, Epithelioid0low10
Sarcoma, Soft Tissue0low10
Sarcoma, Spindle Cell0low10
SCA10low10
Schizoaffective Disorder0low10
Schizophrenia0low10
Schizophrenic Disorders0low10
Schizophreniform Disorders0low10
Schut-Haymaker Type OPCA0low10
Secondary Hypothyroidism0low10
Senile Dementia, Acute Confusional0low10
Senile Dementia, Alzheimer Type0low10
Sensitivity and Specificity0low10
Separation Anxiety Disorder0low10
Shock, Hemorrhagic0low10
Somatization Disorder0medium11
Somatoform Disorders0medium11
Spinocerebellar Ataxia 10low10
Spinocerebellar Ataxia 20low10
Spinocerebellar Ataxia 40low10
Spinocerebellar Ataxia 50low10
Spinocerebellar Ataxia 60low10
Spinocerebellar Ataxia 70low10
Spinocerebellar Ataxia Type 10low10
Spinocerebellar Ataxia Type 20low10
Spinocerebellar Ataxia Type 40low10
Spinocerebellar Ataxia Type 50low10
Spinocerebellar Ataxia Type 60low10
Spinocerebellar Ataxia Type 70low10
Spinocerebellar Ataxia with Slow Eye Movements0low10
Spinocerebellar Ataxia-10low10
Spinocerebellar Ataxia-20low10
Spinocerebellar Ataxia-40low10
Spinocerebellar Ataxia-50low10
Spinocerebellar Ataxia-60low10
Spinocerebellar Ataxia-70low10
Spinocerebellar Ataxia, Autosomal Dominant, with Sensory Axonal Neuropathy0low10
Spinocerebellar Ataxia, Cuban Type0low10
Spinocerebellar Ataxias0low10
Spinocerebellar Ataxias, Dominantly-Inherited0low10
Spinocerebellar Atrophies0low10
Spinocerebellar Atrophy 20low10
Spinocerebellar Atrophy I0low10
Spinocerebellar Atrophy II0low10
Spinocerebellar Degeneration with Slow Eye Movements0low10
Stomach Cancer0low60
Stomach Diseases0low20
Stomach Fistula0low40
Stomach Neoplasms0low60
Stomach Ulcer0low130
Stress Disorder, Post Traumatic0medium21
Stress Disorders, Post-Traumatic0medium21
Stress Disorders, Posttraumatic0medium21
Substance Withdrawal Syndrome0medium41
Suffering, Physical0medium41
Susceptibility, Genetic0low20
Tachyarrhythmia0medium11
Tachycardia0medium11
Tactile Allodynia0low10
Thermal Allodynia0low10
Thyroid Adenoma0low30
Thyroid Cancer0low30
Thyroid Carcinoma0low30
Thyroid Neoplasms0low30
Thyroid-Stimulating Hormone Deficiency0low10
TSH Deficiency0low10
Type 1 Diabetes0low10
Type 1 Diabetes Mellitus0low10
Type 1 Spinocerebellar Ataxia0low10
Type 2 Spinocerebellar Ataxia0low10
Type 4 Spinocerebellar Ataxia0low10
Type 5 Spinocerebellar Ataxia0low10
Type 6 Spinocerebellar Ataxia0low10
Type 7 Spinocerebellar Ataxia0low10
Unipolar Depression0low20
Wadia Swami Syndrome0low10
Wadia-Swami Syndrome0low10
Withdrawal Symptoms0medium41

Research Highlights

Safety/Toxicity (1)

ArticleYear
Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects.
Science (New York, N.Y.), Jul-24, Volume: 325, Issue: 5939		2009
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Long-term Use (5)

ArticleYear
[Effect of GB-115 dipeptide on anxiety in rats with model benzodiazepine withdrawal syndrome].
Eksperimental'naia i klinicheskaia farmakologiia, Volume: 74, Issue: 10		2011
[The absence of tolerance and withdrawal syndrome after the treatment with the new L-tryptophane-containing dipeptide anxiolytic GB-115].
Vestnik Rossiiskoi akademii meditsinskikh nauk, Issue: 7		2011
Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects.
Science (New York, N.Y.), Jul-24, Volume: 325, Issue: 5939		2009
Acute and chronic role of 5-HT3 neuronal system on behavioral and neuroendocrine changes induced by intravenous cholecystokinin tetrapeptide administration in humans.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Volume: 20, Issue: 2		1999
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.
Journal of medicinal chemistry, Jan-01, Volume: 41, Issue: 1		1998
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (6)

ArticleYear
Intestinal metabolism and absorption of cholecystokinin analogs in rats.
Biochemical and biophysical research communications, Apr-05, Volume: 292, Issue: 3		2002
[Improvement of intestinal absorption of peptide and protein drugs by chemical modification with fatty acids].
Nihon rinsho. Japanese journal of clinical medicine, Volume: 56, Issue: 3		1998
Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.
Journal of medicinal chemistry, Jan-01, Volume: 41, Issue: 1		1998
Alternate drug delivery routes for A-71623, a potent cholecystokinin-A receptor agonist tetrapeptide.
Journal of drug targeting, Volume: 4, Issue: 2		1996
CCK-B agonist or antagonist activities of structurally hindered and peptidase-resistant Boc-CCK4 derivatives.
Journal of medicinal chemistry, Jan-08, Volume: 36, Issue: 1		1993
Actions of nizatidine, a selective histamine H2-receptor antagonist, on gastric acid secretion in dogs, rats and frogs.
The Journal of pharmacology and experimental therapeutics, Volume: 239, Issue: 2		1986
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (21)

ArticleYear
Experimental panic provocation in healthy man-a translational role in anti-panic drug development?
Dialogues in clinical neuroscience, Volume: 13, Issue: 4		2011
Blockade of the mineralocorticoid receptor in healthy men: effects on experimentally induced panic symptoms, stress hormones, and cognition.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Volume: 32, Issue: 1		2007
Vigabatrin decreases cholecystokinin-tetrapeptide (CCK-4) induced panic in healthy volunteers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Volume: 25, Issue: 5		2001
Stimulation of either cholecystokinin receptor subtype reduces while antagonists potentiate or sensitize a morphine-induced excitatory response.
Peptides, Volume: 22, Issue: 8		2001
Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.
Journal of medicinal chemistry, Jan-01, Volume: 41, Issue: 1		1998
The cholecystokinin-B receptor antagonist CI-988 failed to affect CCK-4 induced symptoms in panic disorder patients.
Psychopharmacology, Volume: 129, Issue: 3		1997
The panic-inducing properties of the cholecystokinin tetrapeptide CCK4 in patients with panic disorder.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Volume: 6, Issue: 3		1996
Novel CCK analogues and bombesin: a detailed analysis between phosphoinositide breakdown and high-dose inhibition of pancreatic enzyme secretion in three rodent species.
The Journal of pharmacology and experimental therapeutics, Volume: 268, Issue: 2		1994
Dose-response studies of acid secretion after administration of tetragastrin. Studies in duodenal ulcer patients before and after highly selective vagotomy, hemigastrectomy and truncal vagotomy plus antrectomy.
American journal of surgery, Volume: 139, Issue: 6		1980
[Effect of tetragastrin on electrical and contractile activities of the canine stomach and duodenum (author's transl)].
Nihon Heikatsukin Gakkai zasshi, Volume: 16, Issue: 2		1980
The effect of gastric inhibitory polypeptide (GIP) on gastric acid secretion in dogs.
Gastroenterologia Japonica, Volume: 16, Issue: 1		1981
In vitro and in vivo effect of proglumide on cholecystokinin-stimulated amylase release in mouse pancreatic acini.
Gastroenterologia Japonica, Volume: 19, Issue: 1		1984
Effects of C-terminal fragments of cholecystokinin on exocrine and endocrine secretion from isolated perfused rat pancreas.
Endocrinology, Volume: 113, Issue: 6		1983
Effects of portacaval shunt on the rat stomach.
Acta physiologica Scandinavica, Volume: 124, Issue: 3		1985
Stimulation of gastric acid secretion in the rhesus monkey.
Digestive diseases and sciences, Volume: 30, Issue: 1		1985
A behavioral pharmacological study on CCK-8 related peptides in mice.
Neuropeptides, Volume: 8, Issue: 3		1986
Clinical pharmacology of famotidine.
Digestion, Volume: 32 Suppl 1		1985
Stimulation of oxyntic and histaminergic cells in gastric mucosa by gastrin C-terminal tetrapeptide.
The American journal of physiology, Volume: 251, Issue: 4 Pt 1		1986
[Clinico-pharmacological evaluation of omeprazole, as a proton pump inhibitor, compared with H2-blockers].
Nihon rinsho. Japanese journal of clinical medicine, Volume: 50, Issue: 1		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]