Proteins > Polymerase acidic protein
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Polymerase acidic protein

An influenza A virus polymerase acidic protein that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934. [PMID:11779399, PMID:15163504, PMID:15308710, PMID:18660801, PMID:19194459, PMID:22001919, PMID:7060132, PMID:8113737, PMID:9519825, PR

Synonyms

EC 3.1.-.-;
RNA-directed RNA polymerase subunit P2

Research

Bioassay Publications (12)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's6 (50.00)24.3611
2020's3 (25.00)2.80

Compounds (20)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
kojic acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC5012.444612
rimantadineInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC5011.000011
maltolInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC50199.763012
benzohydroxamic acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC50500.000011
n-hydroxyphthalimideInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC50500.000011
epigallocatechin gallateInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC505.860011
pyromeconic acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC5023.809412
allomaltolInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC5016.474412
2-Oxo-4-phenylbutyric acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC50500.000022
benzoylpropionic acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC50500.000011
laudanosolineInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC501.880011
2-hydroxy-4h-isoquinoline-1,3-dioneInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC5015.000022
2-hydroxy-4h-isoquinoline-1,3-dioneInfluenza A virus (A/Puerto Rico/8/1934(H1N1))Ki0.850011
benzoylacrylic acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC50500.000022
N-(7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)benzamideInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC50200.000011
flutimideInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC505.233333

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
salicylic acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))EC50250.000011
benzbromaroneInfluenza A virus (A/Puerto Rico/8/1934(H1N1))Kd48.200011
ribavirinInfluenza A virus (A/Puerto Rico/8/1934(H1N1))EC5021.266733
trenbolone acetateInfluenza A virus (A/Puerto Rico/8/1934(H1N1))Kd90.700011
benzoylpropionic acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))EC50250.000011
diclazurilInfluenza A virus (A/Puerto Rico/8/1934(H1N1))Kd211.000011
2-hydroxy-4h-isoquinoline-1,3-dioneInfluenza A virus (A/Puerto Rico/8/1934(H1N1))EC503.220011
benzoylacrylic acidInfluenza A virus (A/Puerto Rico/8/1934(H1N1))EC50250.000011