A glycogen synthase kinase-3 beta that is encoded in the genome of rat. [OMA:P18266, PRO:DNx]
GSK-3 beta;
EC 2.7.11.26;
Factor A;
FA;
Serine/threonine-protein kinase GSK3B;
2.7.11.1
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| bisindolylmaleimide i | Rattus norvegicus (Norway rat) | IC50 | 0.3600 | 1 | 1 |
| nsc 664704 | Rattus norvegicus (Norway rat) | IC50 | 0.4243 | 2 | 6 |
| ro 31-8220 | Rattus norvegicus (Norway rat) | IC50 | 0.0068 | 1 | 1 |
| 2-phenylindole | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| cyc 202 | Rattus norvegicus (Norway rat) | IC50 | 357.9350 | 1 | 6 |
| paullone | Rattus norvegicus (Norway rat) | IC50 | 5.9067 | 1 | 3 |
| meridianin g | Rattus norvegicus (Norway rat) | IC50 | 232.0000 | 1 | 5 |
| 7-n-butyl-6-(4'-hydroxyphenyl)-5h-pyrrolo(2,3b)pyrazine | Rattus norvegicus (Norway rat) | IC50 | 0.3333 | 1 | 3 |
| curcumin | Rattus norvegicus (Norway rat) | IC50 | 0.0660 | 1 | 1 |
| 7-butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine | Rattus norvegicus (Norway rat) | IC50 | 1.0400 | 1 | 3 |
| alsterpaullone | Rattus norvegicus (Norway rat) | IC50 | 0.0263 | 1 | 3 |
| quercetin | Rattus norvegicus (Norway rat) | IC50 | 31.2750 | 1 | 4 |
| apigenin | Rattus norvegicus (Norway rat) | IC50 | 2.1750 | 1 | 4 |
| luteolin | Rattus norvegicus (Norway rat) | IC50 | 77.7000 | 1 | 4 |
| kaempferol | Rattus norvegicus (Norway rat) | IC50 | 29.3750 | 1 | 4 |
| chrysin | Rattus norvegicus (Norway rat) | IC50 | 5.8500 | 1 | 4 |
| fisetin | Rattus norvegicus (Norway rat) | IC50 | 0.6575 | 1 | 4 |
| alvocidib | Rattus norvegicus (Norway rat) | IC50 | 0.1850 | 1 | 4 |
| 1-azakenpaullone | Rattus norvegicus (Norway rat) | IC50 | 1.5590 | 2 | 4 |
| meridianin a | Rattus norvegicus (Norway rat) | IC50 | 43.5600 | 1 | 5 |
| hymenialdisine | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 3 |