Tetracycline: A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
tetracycline : A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 54675776 |
| CHEBI ID | 27902 |
| SCHEMBL ID | 2116661 |
| SCHEMBL ID | 2116649 |
| SCHEMBL ID | 3098 |
| SCHEMBL ID | 537050 |
| SCHEMBL ID | 21271987 |
| MeSH ID | M0021216 |
| Synonym |
|---|
| BIDD:GT0653 |
| AB00053550-04 |
| CHEBI:27902 , |
| tetrazyklin |
| (4s,4as,5as,6s,12as)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
| tetracyclin |
| tetracyclinum |
| (4s,4as,5as,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
| liquamycin |
| DIVK1C_000827 |
| KBIO1_000827 |
| tetracycline hcl |
| supramycin |
| einecs 200-481-9 |
| achromycin v |
| tetraciclina [inn-spanish] |
| tetracycline (internal use) |
| 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4s-(4alpha,4aalpha,5aalpha,6beta,12aalpha))- |
| tetracyclinum [inn-latin] |
| 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,1 0,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
| tetracycline (jan/usp/inn) |
| D00201 |
| sumycin (tn) |
| SPECTRUM_001034 |
| PRESTWICK2_000140 |
| BSPBIO_001950 |
| SPECTRUM5_001112 |
| IDI1_000827 |
| BSPBIO_000220 |
| agromicina |
| tsiklomitsin |
| deschlorobiomycin |
| tetraverine |
| tetracyn |
| t-125 |
| roviciclina |
| ambramicina |
| piracaps (base) |
| 6-methyl-1,11-dioxy-2-naphthacenecarboxamide |
| tetrafil |
| vetacyclinum |
| criseociclina |
| cefracycline |
| omegamycin |
| hostacyclin |
| tetra-co |
| tetracycline |
| mericycline |
| copharlan |
| vetquamycin-324 (free base) |
| purocyclina |
| ambramycin |
| achromycin |
| tetracycline i |
| nsc-108579 |
| tetradecin |
| centet (base) |
| ciclibion |
| veracin |
| biocycline |
| tetracycline ii |
| sk-tetracycline |
| cyclomycin |
| nsc108579 |
| 60-54-8 |
| panmycin |
| tetrabon |
| orlycycline |
| abramycin |
| lexacycline |
| (4s,4as,5as,6s,12as)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide |
| 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4s,4as,5as,6s,12as)- |
| abricycline |
| amycin |
| solvocin |
| 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo- |
| tsiklomistsin |
| cyclopar |
| hsdb 3188 |
| cefracycline suspension |
| democracin |
| tetracycl |
| bio-tetra |
| limecycline |
| achromycin (naphthacene derivative) |
| micycline |
| liquamycin (veterinary) |
| C06570 |
| tetracycline, >=88.0% (hplc) |
| DB00759 |
| KBIOSS_001514 |
| KBIO2_004082 |
| KBIOGR_000783 |
| KBIO3_001450 |
| KBIO2_006650 |
| KBIO2_001514 |
| PRESTWICK1_000140 |
| PRESTWICK0_000140 |
| NINDS_000827 |
| SPECTRUM3_000565 |
| SPECTRUM2_001329 |
| SPBIO_001457 |
| SPECTRUM4_000352 |
| SPBIO_002159 |
| PRESTWICK3_000140 |
| BPBIO1_000242 |
| tetracycline, >=98.0% (nt) |
| HMS2090B04 |
| e701 |
| NCGC00142507-02 |
| tox21_300150 |
| NCGC00254063-01 |
| dtxcid703645 |
| cas-60-54-8 |
| dtxsid7023645 , |
| SCHEMBL2116661 |
| SCHEMBL2116649 |
| tetraciclina |
| S4490 |
| NCGC00017323-05 |
| NCGC00017323-03 |
| NCGC00017323-04 |
| tetracycline [usp:inn:ban:jan] |
| ccris 9483 |
| unii-f8vb5m810t |
| ec 200-481-9 |
| f8vb5m810t , |
| NCGC00017323-07 |
| tetracycline [who-dd] |
| tetracycline [hsdb] |
| tetracycline [vandf] |
| tetracycline [inn] |
| tetracycline [green book] |
| tetracycline [orange book] |
| tetracycline [usp monograph] |
| tetracycline [jan] |
| tetracycline [ep monograph] |
| tetracycline [usp impurity] |
| (4r,4as,5as,6s,12as)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
| oxytetracycline hydrochloride impurity b [ep impurity] |
| 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4s-(4.alpha.,4a.alpha.,5a.alpha.,6.beta.,12a.alpha.))- |
| lymecycline impurity h [ep impurity] |
| tetracycline component of pylera |
| tetracycline [mi] |
| tetracycline [mart.] |
| pylera component tetracycline |
| T3971 |
| SCHEMBL3098 |
| SCHEMBL537050 |
| OFVLGDICTFRJMM-WESIUVDSSA-N |
| AKOS024277860 |
| AB00053550_06 |
| AB00053550_05 |
| vetquamycin |
| economycin |
| bdbm50237605 |
| tetrabid organon |
| tetracycline base |
| mfcd00151232 |
| AKOS026749977 |
| SR-01000000212-3 |
| sr-01000000212 |
| EN300-374118 |
| SBI-0051530.P003 |
| rkl10088 |
| Z2144222809 |
| CS-8188 |
| NCGC00017323-15 |
| 60-54-8 (free base) |
| NWXMGUDVXFXRIG-WESIUVDSSA-N |
| HY-A0107 |
| Q193045 |
| SCHEMBL21271987 |
| gtpl10927 |
| brodspec |
| ala-tet |
| (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide |
| tetracyclinehydrate |
| BT166207 |
| tetracycline dried down 2.5 microg/ml |
Tetracycline (TC) is a widely used antibiotic suffering from poor water solubility and low bioavailability. Tetracy Cline pollution is an emerging threat in aquatic and terrestrial environments because of its widespread applications in human disease, livestock, and aquaculture.
Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed. Tetracy Cline has been frequently detected in municipal wastewater due to its extended use for various purposes.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Tetracycline has an established track record for safety." | ( Studies of quinacrine and of tetracycline for non-surgical female sterilization. Kessel, E; Mullick, B; Mumford, SD, 1987) | 1.29 |
| "Tetracyclines (TCs) have been extensively used for humans and animal diseases treatment and livestock growth promotion. " | ( An insight into tetracycline photocatalytic degradation by MOFs using the artificial intelligence technique. Abida, O; Baghban, A; Esmaeili, A; Gheytanzadeh, M; Habibzadeh, S; Jabbour, K; Mohaddespour, A, 2022) | 2.51 |
| "Tetracycline (TC) has been frequently detected in various environments, thus promoting the occurrence of resistance in bacterial populations. " | ( Soybean straw biochar activating peroxydisulfate to simultaneously eliminate tetracycline and tetracycline resistance bacteria: Insights on the mechanism. Duan, R; Fu, H; He, M; Li, G; Ma, S; Wang, B; Xu, S; Zhao, P, 2022) | 2.39 |
| "Tetracycline-class drugs have been used for first-line treatment of moderate-to-severe acne and rosacea for decades. " | ( Sarecycline: A Narrow-Spectrum Antibiotic. Adjei, S; Miller, AC; Temiz, LA; Tyring, SK, 2022) | 2.16 |
| "Tetracycline (TC) residues have been noted as an important class of emerging contaminants in the environment, thus fast, straightforward, highly sensitive detection method is becoming an issue that must be addressed. " | ( Dual-functional CDs@ZIF-8/chitosan luminescent film sensors for simultaneous detection and adsorption of tetracycline. Cao, S; Feng, X; Miao, M; Mu, L; Yang, Y, 2022) | 2.38 |
| "Tetracycline has been frequently detected in municipal wastewater due to its extended use for various purposes. " | ( Tetracycline-induced decoupling of symbiosis in microalgal-bacterial granular sludge. Gu, J; Ji, B; Liu, Y; Ma, Y; Wang, S; Zhang, M, 2021) | 3.51 |
| "Many tetracycline analogs have been accessed through both total synthesis and semisynthesis, but key C-ring tetracycline analogs remain inaccessible." | ( Heterologous Catalysis of the Final Steps of Tetracycline Biosynthesis by Cornish, VW; Herbst, E; Lee, A; Snyder, SA; Tang, Y, 2021) | 1.34 |
| "Tetracycline (TC) has been widely used in veterinary medicines and disease treatments, and has been discharged into nature system due to manure application. " | ( [Natural attenuation of tetracycline in the water of Taihu Lake under different environmental conditions]. Duan, LC; Ji, YX; Wang, FH; Wang, GX; Zhang, F; Zhao, B, 2014) | 2.15 |
| "Tetracycline hydrochloride has been shown to produce changes on periodontally involved root surfaces that can potentially enhance periodontal regeneration. " | ( Comparative evaluation of root surface morphology after planing and root conditioning with tetracycline hydrochloride--an in vitro SEM study. Arora, S; Chaubey, KK; Dwivedi, S; Mittal, M; Vashisth, P, ) | 1.79 |
| "Tetracycline (TC) has been used as a broad spectrum antibiotic with low risk of CDI and a photosensitizer (PS) in PDT." | ( In vitro augmented photodynamic bactericidal activity of tetracycline and chitosan against Clostridium difficile KCTC5009 in the planktonic cultures. Chae, H; Choi, S; Lee, H; Yu, J, 2015) | 1.38 |
| "Tetracycline antibiotics have been increasingly used in medical applications and have been found in wastewater treatment plants as a result of human and industrial activities. " | ( Effect of Tetracycline Antibiotics on Performance and Microbial Community of Algal Photo-Bioreactor. Taşkan, E, 2016) | 2.28 |
| "Tetracyclines have been important agents in combating infectious disease since their discovery in the mid-20th century. " | ( Decoding and engineering tetracycline biosynthesis. Pickens, LB; Tang, Y, 2009) | 2.1 |
| "Tetracycline has been widely used for decades in human and veterinary medicines, with incremental residues in the environment and adverse influences on living organisms." | ( Genotoxicity of tetracycline as an emerging pollutant on root meristem cells of wheat (Triticum aestivum L.). Bao, Q; Bao, Y; He, Z; Xie, X; Zhou, Q, 2011) | 1.44 |
| "Tetracyclines have been proposed for AD therapy, although their effects on the aggregation of Aβ protein, particularly their ability to interact in vivo with the Aβ oligomers and/or aggregates, remain to be understood." | ( Tetracycline and its analogues protect Caenorhabditis elegans from β amyloid-induced toxicity by targeting oligomers. Ami, D; Cassata, G; De Luigi, A; Diomede, L; Doglia, SM; Fiordaliso, F; Natalello, A; Salio, M; Salmona, M, 2010) | 2.52 |
| "Oral tetracyclines have been considered the first line treatment for years." | ( Evidence based review of perioral dermatitis therapy. Hall, CS; Reichenberg, J, 2010) | 0.82 |
| "Tetracyclines have been used for treatment of a wide variety of gram-positive and gram-negative bacterial infections since the 1950s. " | ( Tetracycline therapy: update. Roberts, MC, 2003) | 3.2 |
| "Tetracycline has been used to cure filariae of Wolbachia, as a novel means of chemotherapeutic treatment for both ocular and lymphatic filariasis." | ( Brugia pahangi and Wolbachia: the kinetics of bacteria elimination, worm viability, and host responses following tetracycline treatment. Chirgwin, SR; Coleman, SU; Klei, TR; Nowling, JM, ) | 1.06 |
| "Tetracyclines have been extensively used as adjunctives to conventional periodontal therapy. " | ( Antibiotic resistance profile of the subgingival microbiota following systemic or local tetracycline therapy. Colombo, AP; Feres-Filho, EJ; Gonçalves, C; Rodrigues, RM; Souto, R; Uzeda, M, 2004) | 1.99 |
| "Tetracycline (TCN) has been considered the agent of choice for pleurodesis in patients with symptomatic malignant pleural effusions and recurrent pneumothoraces. " | ( Effects of erythromycin on the rabbit pleura: its potential role as a pleural sclerosant. Carvalho, P; Charan, NB; Crowley, JJ; Hawk, PA; Knight, LL; Olson, RD, 1995) | 1.73 |
| "Tetracycline pleurodesis has been shown to be a good alternative for the prevention of recurrence of SP." | ( Spontaneous pneumothorax. Long-term results with tetracycline pleurodesis. Alfageme, I; Beiztegui, A; Hernandez, J; Huertas, C; Moreno, L; Vargas, A, 1994) | 1.26 |
| "Tetracyclines have been widely used as adjuncts in periodontal therapy due to the antimicrobial efficacy of these drugs. " | ( Tetracyclines inhibit Porphyromonas gingivalis-induced alveolar bone loss in rats by a non-antimicrobial mechanism. Chang, KM; Evans, RT; Golub, LM; Klausen, B; McNamara, TF; Murray, PA; Ramamurthy, NS, 1994) | 3.17 |
| "Tetracycline has been one of the most commonly used agents for producing a pleurodesis. " | ( Corynebacterium parvum versus tetracycline as pleural sclerosing agents in rabbits. Carmo, AO; Light, RW; Silva, LM; Teixeira, LR; Vargas, FS; Wang, NS, 1995) | 2.02 |
| "Tetracyclines have been used extensively as antibiotics and growth promoters in the poultry industry. " | ( Tetracycline derivatives inhibit cartilage degradation in cultured embryonic chick tibiae. Chlebek, KA; Cole, AA; Orth, MW; Schmid, TM, ) | 3.02 |
| "Both tetracycline and bleomycin have been shown to be effective for intrapleural instillation, although neither agent has definitively proved advantages over the other." | ( Pleurodesis in malignant pleural effusions: a randomized study of tetracycline versus bleomycin. Aparicio, J; Gil-Suay, V; Martínez-Moragón, E; Rogado, MC; Sanchis, F; Sanchis, J, 1997) | 0.99 |
| "Tetracycline antibiotics have been reported to possess anti-resorptive properties in addition to their anti-microbial actions." | ( The effect of systemic tetracycline on resorption of dried replanted dogs' teeth. Choi, GW; Sae-Lim, V; Trope, M; Wang, CY, 1998) | 1.33 |
| "Tetracycline has been determined in human serum samples by a combination of: (1) synchronous fluorescence spectra of whole sera treated with Mg2+, and (2) the multivariate calibration methods of partial least-squares (PLS-1) and a variant of the recently introduced hybrid linear analysis (HLA), which does not require the knowledge of pure-component spectra. " | ( Enhanced synchronous spectrofluorometric determination of tetracycline in blood serum by chemometric analysis. Comparison of partial least-squares and hybrid linear analysis calibrations. Goicoechea, HC; Olivieri, AC, 1999) | 1.99 |
| "Tetracyclines (TTC) have been used both systemically and locally during periodontal bone grafting procedures, but previous work regarding the effect of TTC on new bone formation has been contradictory. " | ( Histologic evaluation of combining tetracycline and allogeneic freeze-dried bone on bone regeneration in experimental defects in baboons. Drury, GI; Yukna, RA, 1991) | 2 |
| "Tetracycline has been shown to collect selectively in atherosclerotic plaque and is a known photosensitizing agent. " | ( Plaque modification with tetracycline: enhanced tissue ablation with the excimer laser. Berbaum, KS; Cragg, AH; Landas, SK; Smith, TP, 1990) | 2.03 |
| "Tetracycline has been shown in both animal and human studies to be effective in preventing the recurrence of a pleural effusion while producing only minor side effects, such as fever and pleuritic pain." | ( Pleural effusions: pathophysiology and management with intrapleural tetracycline. Oszko, MA, 1988) | 1.23 |
| "Tetracycline sclerotherapy has been described for treatment of intrathoracic and other intracavitary fluid collections." | ( Tetracycline sclerotherapy for chylous fistula following neck dissection. Alessi, D; Calcaterra, TC; Metson, R, 1986) | 2.44 |
Tetracyclines inhibit not only bacterial but also mitochondrial translation, thus imposing a low level of mitochondrial stress on eukaryotic cells. Tetracy Cline remains the treatment of choice for chronic maintenance of uncomplicated acne.
Treatment with tetracycline or rifampin for two weeks usually results in cure. Treatment with TMP-SMZ alone (four to eight weeks) or in combination with streptomycin (two to four weeks) resulted in a relapse rate of 16.6%.
Tetracycline has been widely used for decades in human and veterinary medicines. The aim of this study was to evaluate the compliance, adverse effects and effectiveness of this treatment with a new galenic three-in-one capsule formulation containing bismuth.
The goal of this study was to evaluate the pharmacokinetic interaction between tegoprazan and triple-antibiotic therapy containing metronidazole, tetracycline, and bismuth. IPC had no pharmacokinetics effect on the rate of absorption of tetr Tracycline.
The antimicrobial activities of tetracycline, mupirocin, and fusidic acid are tested in combination with Epicatechin Gallate (ECG), and Ethyl Gallate. Dose-dependent inhibition of Salmonella typhimurium DT104 growth is observed. We have compared plasma quinine levels on day 2, day 5 and day 7 in twenty-one patient.
| Excerpt | Reference | Relevance |
|---|---|---|
| " We have compared plasma quinine levels on day 2, day 5 and day 7 (before and at 2 hours after dosing) in twenty-one patients with acute falciparum malaria who were treated with quinine alone (8 patients) or quinine in combination with tetracycline (8 patients) or quinine with tetracycline and primaquine (5 patients)." | ( Plasma quinine levels in patients with falciparum malaria when given alone or in combination with tetracycline with or without primaquine. Bunnag, D; Harinasuta, T; Karbwang, J; Molunto, P, 1991) | 0.68 |
| "The efficacy and toxicity of oral quinine combined with oral chloroquine were studied in 50 Thai men with uncomplicated falciparum malaria." | ( Therapeutic effects of chloroquine in combination with quinine in uncomplicated falciparum malaria. Chantra, A; Chindanond, D; Clemens, R; Phophak, N; Pukrittayakamee, S; Vanijanonta, S, 1996) | 0.29 |
| "The influence of a 50 Hz magnetic field (MF) on avian and mammalian embryogenesis, the MF level and vector, as well as the effect of exposure to MF (50 Hz, 10 mT) in combination with X-rays has been recently reported [2,3]." | ( Developmental effects of magnetic field (50 Hz) in combination with ionizing radiation and chemical teratogens. Bednár, V; Jerábek, J; Pafková, H; Tejnorová, I, 1996) | 0.29 |
| " This article aims to review the "additional" effect of a subgingival irrigation with chlorhexidine, or a local or systemic application of tetracycline or metronidazole, performed in combination with a single course of scaling and root planing in patients with chronic adult periodontitis." | ( Microbiological response to mechanical treatment in combination with adjunctive therapy. A review of the literature. Bollen, CM; Quirynen, M, 1996) | 0.5 |
| " The technique combined tetracycline treatment of a root planed root, grafting of the osseous defect with a demineralized freeze-dried bone allograft combined with tetracycline and the placement of a bioabsorbable matrix membrane, made of polylactic acid softened with citric acid ester." | ( A clinical evaluation of guided tissue regeneration with a bioabsorbable matrix membrane combined with an allograft bone graft. A series of case reports. Harris, RJ, 1997) | 0.6 |
| "The purpose of this study was to histologically evaluate furcation defects in humans treated with an allograft-alloplast-tetracycline composite graft combined with an absorbable membrane for guided tissue regeneration (GTR)." | ( Treatment of furcation defects with an allograft-alloplast-tetracycline composite bone graft combined with GTR: human histologic evaluation of a case report. Harris, RJ, 2002) | 0.77 |
| " pylori eradication rate in both metronidazole-sensitive and -resistant strains following quadruple therapy using single-triple capsules of bismuth biskalcitrate, metronidazole and tetracycline, given with omeprazole." | ( Efficacy and safety of single-triple capsules of bismuth biskalcitrate, metronidazole and tetracycline, given with omeprazole, for the eradication of Helicobacter pylori: an international multicentre study. Borody, T; Dallaire, C; De Boer, WA; Fallone, CA; Farley, A; Mégraud, F; O'Morain, C; Piotrowski, J; Schuman, R; Spénard, J; Tytgat, G, 2003) | 0.73 |
| "Summary We report a case of protothecosis in an 18-year-old female student caused by Prototheca zopfii successfully treated with amikacin combined with tetracyclines." | ( Protothecosis successfully treated with amikacin combined with tetracyclines. Liu, W; Lv, G; Shen, Y; Wu, S; Zhao, J, 2004) | 0.76 |
| "To evaluate the effect of mechanical periodontal treatment combined with tetracycline on periodontal attachment, distances of cementum-enamel junction (CEJ) to the bone defect bottom and to the alveolar crest, and avidity of serum IgG against Porphyromonas gingivalis (Pg) lipopolysaccharide (LPS) in patients with aggressive periodontitis." | ( [Mechanical periodontal treatment combined with tetracycline for aggressive periodontitis]. Huang, SG; Xie, M; Zhang, HF; Zhang, XQ; Zhang, Y, 2006) | 0.82 |
| "Twenty-six patients with aggressive periodontitis were divided equally into two groups to receive mechanical periodontal treatment combined with tetracycline or exclusive mechanical periodontal treatment, with another 20 periodontally healthy subjects serving as the control group." | ( [Mechanical periodontal treatment combined with tetracycline for aggressive periodontitis]. Huang, SG; Xie, M; Zhang, HF; Zhang, XQ; Zhang, Y, 2006) | 0.79 |
| "Mechanical periodontal treatment combined with tetracycline produces favorable effects in patients with aggressive periodontitis." | ( [Mechanical periodontal treatment combined with tetracycline for aggressive periodontitis]. Huang, SG; Xie, M; Zhang, HF; Zhang, XQ; Zhang, Y, 2006) | 0.85 |
| "A molecularly imprinted polymer solid phase extraction (MISPE) method combined with flow-injection chemiluminescence (FI-CL) for the determination of residual tetracycline (TC) in fish samples is presented." | ( Molecularly imprinted on-line solid-phase extraction combined with flow-injection chemiluminescence for the determination of tetracycline. He, C; He, D; Xiong, Y; Zhang, Z; Zhou, H, 2006) | 0.74 |
| " Rosacea is most commonly managed with topical metronidazole, sometimes in combination with oral antibiotics." | ( Managing rosacea: a review of the use of metronidazole alone and in combination with oral antibiotics. Balkrishnan, R; Conde, JF; Feldman, SR; Fleischer, AB; Yelverton, CB, 2007) | 0.34 |
| "75% lotion is more effective when used in combination with doxycycline 20 mg dosed twice daily." | ( Managing rosacea: a review of the use of metronidazole alone and in combination with oral antibiotics. Balkrishnan, R; Conde, JF; Feldman, SR; Fleischer, AB; Yelverton, CB, 2007) | 0.34 |
| "The in vitro antibacterial activity against antibiotic-resistant Propionibacterium acnes of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin antibiotics was investigated." | ( In vitro activity of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin against Propionibacterium acnes. Kim, IH; Lim, YH; Seo, JJ, 2007) | 0.34 |
| " In this study we aimed to determine the in vitro activity of hydrogen peroxide (H2O2; reactive oxygen intermediate) and acidified sodium nitrite (ASN; reactive nitrogen intermediate) alone and in combination with rifampicin (RIF) and tetracycline (TET) against four clinical isolates of Brucella melitensis." | ( [In vitro effect of reactive nitrogen and oxygen intermediates alone and in combination with some antibiotics against Brucella melitensis clinical isolates]. Coban, AY; Durupinar, B; Tanyel, E; Taşdelen Fişgin, N; Tülek, N, 2009) | 0.54 |
| "The antimicrobial activities of tetracycline, mupirocin, and fusidic acid are tested in combination with Epicatechin Gallate (ECG), and Ethyl Gallate (EG) using 2 Methicillin resistant (MRSA) and 2 Methicillin sensitive (MSSA) strains of Staphylococcus aureus." | ( In vitro drug interactions of gallates with antibiotics in Staphylococcus Aureus. Chu Sing Lim, L; Sakharkar, KR; Sakharkar, MK; Soe, WM; Tzer Pin Lin, R, 2010) | 0.64 |
| "The hepatic organic anion transporting polypeptides (OATPs) influence the pharmacokinetics of several drug classes and are involved in many clinical drug-drug interactions." | ( Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR, 2012) | 0.38 |
| "The in vitro activity of mastoparan-AF, an amphipathic antimicrobial peptide isolated from the hornet venom of Vespa affinis, alone and in combination with various clinically used antibiotics, was investigated against 21 Escherichia coli isolates/strains." | ( In vitro activity of mastoparan-AF alone and in combination with clinically used antibiotics against multiple-antibiotic-resistant Escherichia coli isolates from animals. Hou, RF; Lin, CF; Lin, CH; Shia, WY; Shyu, CL; Tu, WC, 2012) | 0.38 |
| "5-4) results against the bacterium in combination with ampicillin, ciprofloxacin, tetracycline or metronidazole." | ( In vitro effects of N-acetyl cysteine alone and in combination with antibiotics on Prevotella intermedia. Jang, EY; Lee, JY; Moon, JH; Shim, KS, 2015) | 0.64 |
| " In combination with tannins, antibiotics showed increased MICs, suggesting that tannins interfered with antibacterial activity." | ( Effect of tannic and gallic acids alone or in combination with carbenicillin or tetracycline on Chromobacterium violaceum CV026 growth, motility, and biofilm formation. Dusane, DH; O'May, C; Tufenkji, N, 2015) | 0.64 |
| " In combination with TH, the gel scaffold exhibited beneficial effects on osteoblast activity, which suggested a promising future for local treatment of pathologies involving bone loss." | ( Injectable alginate/hydroxyapatite gel scaffold combined with gelatin microspheres for drug delivery and bone tissue engineering. Chen, Y; Hu, X; Ling, Z; Miao, Y; Tan, H; Xing, X; Yan, J; Zhou, T, 2016) | 0.43 |
| "To assess the efficacy and safety of omeprazole given with the new single capsule of bismuth, metronidazole and tetracycline (OBMT) compared with quadruple treatment consisting of omeprazole, bismuth, amoxicillin and clarithromycin (OBAC) for Helicobacter pylori eradication in duodenal ulcer patients." | ( New single capsule of bismuth, metronidazole and tetracycline given with omeprazole versus quadruple therapy consisting of bismuth, omeprazole, amoxicillin and clarithromycin for eradication of Helicobacter pylori in duodenal ulcer patients: a Chinese pro Chen, Y; Du, Y; Li, Y; Liu, D; Lv, N; Pan, X; Wang, H; Wang, J; Wu, K; Xie, Y; Xu, J; Zeng, Z; Zhang, G, 2018) | 0.95 |
| " However, few researches focused on the mechanism and their contribution of TC removal through microorganisms combined with zero-valent iron (ZVI) in wastewater treatment field." | ( The enhancement of tetracycline degradation through zero-valent iron combined with microorganisms during wastewater treatment: Mechanism and contribution. Ding, J; Liu, Y; Su, Z; Yan, M; Zhu, T, 2023) | 1.24 |
The bioavailability of a single 250-mg oral dose of tetracycline hydrochloride was studied in seven patients following Billroth-II gastrectomy.
| Excerpt | Reference | Relevance |
|---|---|---|
| " Evaluation of the absorption rate was done by means of urinary excretion measurements." | ( Effect of magnesium trisilicate and citric acid on the biovailability of tetracycline in man. Daabis, NA; Khalil, SA; Naggar, VF; Wafik, M, ) | 0.36 |
| "The bioavailability of tetracycline in the presence and absence of a porcine gastric mucin dispersion (1% W/V) has been studied by in vivo perfusion of the rat small intestine, the rat everted gut, a diffusion cell technique and the Sartorius Absorption Simulator Apparatus." | ( The effect of mucin on the bioavailability of tetracycline from the gastrointestinal tract; in vivo, in vitro correlations. Abbs, ET; Barry, BW; Braybrooks, MP, 1975) | 0.82 |
| " Apparently, the reduction in tetracycline bioavailability previously reported with a kaolin-pectin suspension is not peculiar to kaolin-pectin but can be expected with almost any antidiarrheal whose mechanism of action is adsorptive in nature." | ( Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. Albert, KS; DeSante, KA; DiSanto, AR; Welch, RD, 1979) | 0.95 |
| "Relative bioavailability after oral administration of a single dose and Cmin levels of tetracycline in plasma after multiple doses were determined in groups of well-nourished and under-nourished subjects." | ( Influence of nutritional status on plasma levels and relative bioavailability of tetracycline. Krishnaswamy, K; Raghuram, TC, 1977) | 0.71 |
| " However, the rate of absorption appeared to be more rapid in the exercise than in the rest period." | ( Effect of exercise on the serum level and urinary excretion of tetracycline, doxycycline and sulphamethizole. Hinkka, H; Neuvonen, PJ; Ylitalo, P, 1977) | 0.5 |
| " Concurrent administration of 2 gm of sodium bicarbonate to 2 of the normal subjects resulted in no impairment of either the rate or extent of tetracycline absorption from capsules, suggesting that the effect of elevated gastric pH on tetracycline bioavailability may relate to formulation." | ( Tetracycline absorption in elderly patients with achlorhydria. Benson, J; Chapron, DJ; Kramer, PA; Mercik, SA, 1978) | 1.9 |
| "The bioavailability of a single 250-mg oral dose of tetracycline hydrochloride was studied in seven patients following Billroth-II gastrectomy in comparison with seven control subjects matched for age and body weight." | ( Absorption of oral tetracycline in patients with Billroth-II gastrectomy. Dengler, HJ; Greenblatt, DJ; Ochs, HR, 1978) | 0.84 |
| "The influence of various test meals and fluid volumes on the relative bioavailability of commercial formulations of doxycycline hyclate and tetracycline hydrochloride was studied in healthy human volunteers." | ( Bioavailability of tetracycline and doxycycline in fasted and nonfasted subjects. Craig, WA; Koch, PA; Lau, CC; Welling, PG, 1977) | 0.79 |
| " The rate of absorption of from two to six of the amino acids tested was lower in 7 of the patients than in the control subjects." | ( Malabsorption of essential amino acids in tropical sprue. Corcino, JJ; Klipstein, FA, 1975) | 0.25 |
| " The bile salts are important surfactants in man, and modify the absorption rate of tetracycline, but not of doxycycline, sulphadimidine and cycloserine." | ( Drug absorption in patients with T-tube after cholecystectomy. Aukee, S; Jussila, J; Karjalainen, P; Venho, VM, 1975) | 0.48 |
| "The period of time after administration over which blood level measurements are required to obtain a reliable bioavailability comparison of two or more formulations of the same drug was considered by the analysis of bioavailability data taken from the literature." | ( Comparative bioavailabilities from truncated blood level curves. Lovering, EG; McGilveray, IJ; McMillan, I; Tostowaryk, W, 1975) | 0.25 |
| "Difference in the levels of bioavailability of 4 types of tetracycline hydrochloride tablets was shown on rabbits and guinea pigs." | ( [Differentiation of the degree of bioavailability of peroral drug forms of tetracycline hydrochloride in experiments on laboratory animals]. Ermolova, OB; Zak, AF, 1976) | 0.73 |
| " The bioavailability of substandard product as determined from 48 h urinary tetracycline excretion was significantly lower as compared to standard product both in well-nourished and undernourished subjects." | ( Bioavailability of different brands of tetracycline in undernourished subjects. Krishnaswamy, K; Raghuram, TC; Santosh, KK, 1992) | 0.78 |
| "The role of bacteria in the bioavailability of protein-bound vitamin B12 was examined in eight elderly subjects who had atrophic gastritis and in eight normal controls." | ( Reversal of protein-bound vitamin B12 malabsorption with antibiotics in atrophic gastritis. Goldin, BR; Golner, BB; Morrow, FD; Russell, RM; Suter, PM, 1991) | 0.28 |
| "A pilot bioavailability study was carried out to evaluate the drug interaction and influence of dioctyl sodium sulfosuccinate (DS) on the absorption/bioavailability of tetracycline." | ( Influence of dioctyl sodium sulfosuccinate on the absorption of tetracycline. Fairweather, WR; Hunt, JP; Knapp, G; Prasad, VK; Shah, VP, ) | 0.56 |
| " Earlier studies showed that concentrates reduce the bioavailability of tetracyclines more than a conventional milk replacer." | ( Studies on the bioavailability of tetracycline chloride after oral administration to calves and pigs. Bengtsson, B; Jacobsson, SO; Korpe, C; Luthman, J, 1989) | 0.79 |
| "A 2 X 2 crossover design trial was conducted in gilts to determine the bioavailability and pharmacokinetics of tetracycline hydrochloride." | ( Bioavailability, pharmacokinetics, and plasma concentration of tetracycline hydrochloride fed to swine. Bane, DP; Bevill, RF; Hall, WF; Kniffen, TS; Koritz, GD, 1989) | 0.73 |
| " The tissue disposition and bioavailability of 3H-tetracycline were examined in the channel catfish (Ictalurus punctatus) after intravascular (4 mg/kg body weight) and per os (4 and 80 mg/kg) dosing." | ( Disposition and bioavailability of 3H-tetracycline in the channel catfish (Ictalurus punctatus). Guarino, AM; McPhearson, RM; Plakas, SM, 1988) | 0.8 |
| " In particular, recent simulation studies based on newly determined complex stability constants have drawn attention to the potential influence of Ca2+ and Mg2+ ions on the bioavailability of various TC derivatives in blood plasma." | ( Metal ion-tetracycline interactions in biological fluids. Part 8. Potentiometric and spectroscopic studies on the formation of Ca(II) and Mg(II) complexes with 4-dedimethylamino-tetracycline and 6-desoxy-6-demethyl-tetracycline. Berthon, G; Decock-Le Révérend, B; Kozlowski, H; Lambs, L; Venturini, M, 1988) | 0.68 |
| " Computer simulations run on this occasion showed that the stoichiometry of these species do actually condition the bioavailability of the antibiotics in blood plasma during treatment, the fraction of free base being quite negligible with regard to the metal-bound one." | ( Metal ion-tetracycline interactions in biological fluids. Part 3. Formation of mixed-metal ternary complexes of tetracycline, oxytetracycline, doxycycline and minocycline with calcium and magnesium, and their involvement in the bioavailability of these an Berthon, G; Brion, M; Lambs, L, 1984) | 0.67 |
| "The relative bioavailability of lymecycline and tetracycline hydrochloride was compared in 12 healthy volunteers in a double-blind cross-over study using a high performance liquid chromatographic method for plasma and urine analyses." | ( Comparative bioavailability of tetracycline and lymecycline. Hermansson, J; Sjölin-Forsberg, G, 1984) | 0.81 |
| " The results were used, together with those previously obtained on the complexation of these tetracyclines with proton and calcium, to assess the influence of the two alkali earth metal ions on the bioavailability of these drugs in blood plasma." | ( Metal ion-tetracycline interactions in biological fluids. 2. Potentiometric study of magnesium complexes with tetracycline, oxytetracycline, doxycycline, and minocycline, and discussion of their possible influence on the bioavailability of these antibioti Berthon, G; Brion, M; Lambs, L, 1983) | 0.89 |
| " The biliary excretion and hepatic levels of [3H]tetracycline were decreased whereas bile flow did not vary and plasma bioavailability of radioactivity increased in comparison with control rats." | ( Incidence of experimental ochratoxicosis on hepatic disposition of [3H]tetracycline and chloramphenicol in rats. Alvinerie, M; Galtier, P, 1983) | 0.75 |
| " Intramuscularly, tetraolean was well absorbed in the site of application, and, according to the animal species, it developed proper plasmal therapeutic concentrations at the following rates: calves--20 mg/kg body mass at 12-hour intervals; pigs--10 mg/kg at 6-hr intervals, or 20 mg/kg at 12-hr intervals; horses--10 mg/kg at 12-hr intervals or 20 mg/kg at 24-hr intervals." | ( [Tolerance for tetraolean i.m. and the blood levels in agricultural animals]. Chaleva, E; Dilov, P; Dimitrov, K; Iotsev, M; Panchev, I, 1984) | 0.27 |
| " The program is applicable to any drug in an individual, provided that the drug follows one-compartment pharmacokinetics after oral administration, while the fraction of the oral dose absorbed, the volume of distribution, the absorption rate constant and the elimination rate constant of the drug in this individual are known." | ( Prediction of multiple-dose blood level curves of drugs administered four times daily at non-uniform dosing intervals. Ng, PK, 1981) | 0.26 |
| " In four normal volunteers taking digoxin daily for four weeks, urinary excretion of DRPs was greatest after a poorly absorbed tablet was ingested, and least after intravenous administration, Stool cultures from subjects known to make DRPs in vivo ("excretors") converted digoxin to DRPs; cultures from nonexcretors did not." | ( Inactivation of digoxin by the gut flora: reversal by antibiotic therapy. Butler, VP; Lindenbaum, J; Rund, DG; Saha, JR; Tse-Eng, D, 1981) | 0.26 |
| " 6 The bioavailability of tetracycline from tablets and suspension was found to be similar (31." | ( Effect of cimetidine on the absorption of orally administered tetracycline. Bradbrook, ID; Fisher, P; House, F; Inns, P; Morrison, PJ; Rogers, HJ, 1980) | 0.8 |
| " Antibiotic bioavailability was measured by area under the plasma level-time curve, peak plasma level and urinary elimination." | ( Effect of cimetidine on absorption of oral tetracycline in mice. Garty, M; Hurwitz, A, 1980) | 0.52 |
| " Antibiotic bioavailability as measured by area under the serum level-time curve, peak serum level, and urinary elimination was not affected by cimetidine or sodium bicarbonate." | ( Effect of cimetidine and antacids on gastrointestinal absorption of tetracycline. Garty, M; Hurwitz, A, 1980) | 0.5 |
| " It was found that tetraolean used intramuscularly in the early postoperative periods was well absorbed into the lymph, reached its maximum level within 2 hours and exceeded that in the blood." | ( [Tetraolean pharmacokinetics in the lymph and blood in complicated, acute inflammatory diseases of the abdominal cavity organs]. Iarema, IV; Makarenkov, IS; Marshak, AM; Panchenkov, RT; Urtaev, BM, 1980) | 0.26 |
| " Advantages of the tablets with the film coating in the main characteristics, such as bioavailability and levels of tetracycline-like admixtures were shown." | ( [Quality and stability of tetracycline tablets]. Grakovskaia, LK; Nesterova, LIa; Okhotnikova, VF; Shadyro, LL, 1980) | 0.77 |
| " The bioavailability was in general low for all the three tetracyclines." | ( Bioavailability of oxytetracycline, tetracycline and chlortetracycline after oral administration to fed and fasted pigs. Gyrd-Hansen, N; Nielsen, P, 1996) | 0.85 |
| " This study attempts to add to the understanding of the systemic bioavailability of fluoride ingested with milk compared with water, by measuring its uptake into developing incisors of sheep." | ( Fluoride uptake into the developing enamel and dentine of sheep incisors following daily ingestion of fluoridated milk or water. Coote, GE; Cutress, TW; Gao, J; Suckling, GW, 1996) | 0.29 |
| "The effect of milk added to coffee or black tea on the bioavailability of tetracycline was evaluated in 12 healthy volunteers according to a crossover design." | ( The influence of coffee with milk and tea with milk on the bioavailability of tetracycline. Jung, H; Moreno-Esparza, R; Peregrina, AA; Rodriguez, JM, 1997) | 0.76 |
| "To determine whether the observed decrease in tetracycline bioavailability is due to the active drug bismuth subsalicylate via complexation, or to magnesium aluminum silicate (Veegum), an inactive excipient present only in the liquid formulation of bismuth subsalicylate, which might adsorb the tetracycline, rendering it unavailable for systemic absorption." | ( Reduced tetracycline bioavailability caused by magnesium aluminum silicate in liquid formulations of bismuth subsalicylate. Clendening, CE; Dansereau, RJ; Deepe, GS; Dunn, AB; Healy, DP; Mounts, AW, 1997) | 0.99 |
| " The hydroxamate peptidomimetic inhibitor batimastat and its orally bioavailable analogue marimastat, which bind covalently to the zinc atom at the MMP-active site, were the first MMP inhibitors to be studied in detail." | ( Development of matrix metalloproteinase inhibitors in cancer therapy. Eckhardt, SG; Hidalgo, M, 2001) | 0.31 |
| " Findings suggest that interference with anti-implantation action of ormeloxifene by tetracycline might be due primarily to the almost complete abolition of its estrogen antagonistic activity at the uterine level, effected by decreased bioavailability of ormeloxifene and/or its active metabolite(s) by altered enterohepatic recirculation because of the effect on gut microflora." | ( Interaction with anti-implantation and estrogen antagonistic activities of dl-ormeloxifene, a selective estrogen receptor modulator, by tetracycline in female Sprague-Dawley rats. Ghosh, R; Kamboj, VP; Singh, MM, 2001) | 0.74 |
| "The objective of this study was to determine the impact of omeprazole on bismuth (Bi) bioavailability when given in a three-in-one capsule containing bismuth biskalcitrate, metronidazole, and tetracycline." | ( Influence of omeprazole on bioavailability of bismuth following administration of a triple capsule of bismuth biskalcitrate, metronidazole, and tetracycline. Aumais, C; Lefebvre, M; Massicotte, J; Spénard, J; Tremblay, C, 2004) | 0.71 |
| "Food significantly decreased the relative bioavailability of each drug but formulation was without effect." | ( Effects of food and formulation on the relative bioavailability of bismuth biskalcitrate, metronidazole, and tetracycline given for Helicobacter pylori eradication. Aumais, C; Brunet, JS; Grace, M; Lefebvre, M; Massicotte, J; Spénard, J; Tremblay, C, 2005) | 0.54 |
| " IPC had no pharmacokinetic effect on the rate of absorption of tetracycline." | ( Effect of an oral iron(III)-hydroxide polymaltose complex on tetracycline pharmacokinetics in patients with iron deficiency anemia. Geisser, P; Jacobs, YL; Potgieter, MA; Pretorius, SG; Venter, C; Venter, JL, 2007) | 0.82 |
| " Human oral bioavailability is an important pharmacokinetic property, which is directly related to the amount of drug available in the systemic circulation to exert pharmacological and therapeutic effects." | ( Hologram QSAR model for the prediction of human oral bioavailability. Andricopulo, AD; Moda, TL; Montanari, CA, 2007) | 0.34 |
| "The effect on the bioavailability of the antimicrobial agents (ciprofloxacin and tetracycline), which are well known to form chelates with cationic metals such as calcium, was evaluated in 20 healthy male volunteers according to an open, random crossover fashion using a Kampo preparation, byakkokaninjinto (TJ-34) which contains various cationic metals including calcium." | ( Effect of a Kampo preparation, byakkokaninjinto, on pharmacokinetics of ciprofloxacin and tetracycline. Abe, F; Haniuda, M; Hasegawa, T; Hitoshi, K; Katoh, M; Kurono, S; Nadai, M; Ohnishi, M; Saito, H, 2009) | 0.8 |
| " Furthermore, the study showed that tetracycline oral bioavailability is very small." | ( Pharmacology of tetracycline water medication in swine. Almond, GW; Baynes, RE; Mason, SE; Riviere, JE; Scheidt, AB, 2009) | 0.97 |
| " These "in combo" PAMPA data were used to predict the human absolute bioavailability of the ampholytes." | ( The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability. Avdeef, A; Sun, N; Tam, KY; Tsinman, O, 2010) | 0.36 |
| "Oral bioavailability (F) is a product of fraction absorbed (Fa), fraction escaping gut-wall elimination (Fg), and fraction escaping hepatic elimination (Fh)." | ( Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV, 2010) | 0.36 |
| " Several analogs have also shown promising oral bioavailability in rats and cynomolgus monkey." | ( Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. Clark, RB; Hunt, DK; Lofland, D; O'Brien, WJ; Plamondon, L; Sun, C; Xiao, XY, 2011) | 0.6 |
| " Two compounds were identified that exhibit both oral bioavailability in rat and clinically relevant bacterial susceptibility profiles against major respiratory pathogens." | ( Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. Achorn, C; Chen, CL; Clark, RB; Deng, Y; Fyfe, C; Grossman, TH; He, M; Hogan, PC; Hunt, DK; O'Brien, WJ; Plamondon, L; Rönn, M; Sutcliffe, JA; Xiao, XY; Zhu, Z, 2012) | 0.38 |
| " The findings of this study have important implications for the risk assessment of engineered nanomaterials - in aquatic environments nano-NiO (and likely other metal oxide nanomaterials) can strongly adsorb tetracycline antibiotics, resulting in the changes of environmental risks of the metal oxide nanomaterials and/or bioavailability of the adsorbed contaminants." | ( Adsorption of tetracycline to nano-NiO: the effect of co-existing Cu(ii) ions and environmental implications. Chen, W; Duan, L; Li, L; Xu, Z, 2014) | 0.95 |
| " Tetracyclines form metal-complexes in natural waters, which could reduce their bioavailability for bacterial uptake." | ( Organic acids enhance bioavailability of tetracycline in water to Escherichia coli for uptake and expression of antibiotic resistance. Boyd, SA; Li, H; Teppen, BJ; Tiedje, JM; Zhang, Y, 2014) | 1.58 |
| "Complexation of tetracycline with dissolved organic matter (DOM) in aqueous solution could alter the bioavailability of tetracycline to bacteria, thereby alleviating selective pressure for development of antibiotic resistance." | ( Influence of Dissolved Organic Matter on Tetracycline Bioavailability to an Antibiotic-Resistant Bacterium. Boyd, SA; Chen, Z; Gao, Y; Li, H; Zhang, Y; Zhu, D, 2015) | 1.03 |
| " The objectives of this study were (a) to assess the tetracycline (Tc) bioavailability in a clay and in a sandy soil, and (b) to evaluate the effects of the Tc and cow manure on the structure and function of soil microbial communities." | ( Soil microbial response to tetracycline in two different soils amended with cow manure. Chessa, L; Garau, G; Mangia, NP; Pinna, MV; Pusino, A, 2016) | 0.98 |
| " The bioavailability of antibiotics varies greatly: some antibiotics remain active in soils (florfenicol, β-lactams), whereas others may be rapidly sorbed and thus not bioavailable (tetracycline, macrolides, quinolones)." | ( Not All Antibiotic Use Practices in Food-Animal Agriculture Afford the Same Risk. Call, DR; Mitchell, SM; Subbiah, M, 2016) | 0.63 |
| " Therefore, beneficial biological effects were demonstrated both in vitro and in vivo, which indicated that the bone-targeting effects of micelles greatly enhance the bioavailability of SV on the implant-bone interface, and the provision of SV-loaded targeting micelles alone exhibits the potential for extensive application in improving local bone regeneration and osseointegration, especially in osteoporotic subjects." | ( Study of a new bone-targeting titanium implant-bone interface. Cai, L; Lai, R; Li, S; Li, Z; Liu, X; Sun, T; Wang, X; Wang, Y; Zhang, Y; Zhou, L, ) | 0.13 |
| " This study investigated the bioavailability of tetracycline sorbed on three soils (Webster clay loam, Capac sandy clay loam, and Oshtemo loamy sand) to a fluorescent Escherichia coli bioreporter under unsaturated conditions using agar diffusion assay, microscopic visualization, and model simulation." | ( Bioavailability of Soil-Sorbed Tetracycline to Escherichia coli under Unsaturated Conditions. Boyd, SA; Chen, Z; Gao, Y; Li, H; Teppen, BJ; Tiedje, JM; Wang, G; Zhang, W; Zhang, Y; Zhu, D, 2017) | 1 |
| " coli MC4100/pTGM strain was used to probe the bioavailability of tetracycline sorbed by smectite clay, a class of common soil minerals." | ( Bioavailability of tetracycline to antibiotic resistant Escherichia coli in water-clay systems. Boyd, SA; Li, H; Teppen, BJ; Tiedje, JM; Zhang, W; Zhang, Y; Zhu, D, 2018) | 1.05 |
| "The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs." | ( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019) | 0.51 |
| " To understand the potential bioavailability of tetracycline (TC) in soil environments, this study explored the behaviors of TC adsorbing to six types of soils sampled from different regions of China." | ( Factors affecting sorption behaviors of tetracycline to soils: Importance of soil organic carbon, pH and Cd contamination. Chen, Y; Deng, D; Hu, C; Li, Y; Luo, L, 2020) | 1.08 |
| " Specifically, the uptake of hazardous chemicals by plastics particles may affect the distribution and bioavailability of the chemicals." | ( Adsorption characteristics of tetracycline onto particulate polyethylene in dilute aqueous solutions. Chen, CW; Dong, CD; Ho, TB; Hsieh, SL; Huang, CP; Nguyen, TB; Tsai, WP, 2021) | 0.91 |
| " The results illuminated that pyrolysis temperature is a crucial factor of fraction and bioavailability of Mn and other heavy metals in the resultant biochar and pyrolysis temperature under 450 °C may be most suitable for reutilization without potential risk." | ( Reutilization of manganese enriched biochar derived from Phytolacca acinosa Roxb. residue after phytoremediation for lead and tetracycline removal. Chen, H; Chi, T; Du, C; Liu, B; Wu, H; Yu, G; Zhou, L; Zhu, X, 2022) | 0.93 |
| ", NaCl) could influence the bioavailability of antibiotics to bacteria." | ( NaCl salinity enhances tetracycline bioavailability to Escherichia coli on agar surfaces. Chen, Z; Li, H; Luo, Y; Peng, A; Sallach, JB; Yin, L; Zhang, W, 2022) | 1.03 |
| "In aquatic environment, engineered materials may inevitably interact with the coexisted organic pollutants, which affect their bioavailability and toxicity." | ( Combined exposure to titanium dioxide and tetracycline induces neurotoxicity in zebrafish. Fu, Z; He, Y; Hu, Q; Xu, L; Yang, X, 2023) | 1.17 |
| " In vivo animal studies using a Sprague Dawley rat model showed antibiotic administration using HF-MAP achieved a sustained release profile, in comparison with animals receiving oral gavage and intravenous (IV) injection, with a transdermal bioavailability of 19." | ( Hydrogel-forming microarray patch mediated transdermal delivery of tetracycline hydrochloride. Donnelly, RF; Kelly, SA; Larrañeta, E; Li, L; McCarthy, HO; Vora, LK; Zhao, L, 2023) | 1.15 |
| "To investigate how cyclosporine A, a nonspecific efflux-pump blocker, affects the plasma concentrations and oral bioavailability of tigecycline, oxytetracycline, chlortetracycline, doxycycline, minocycline, and tetracycline." | ( Bioavailability of tetracyclines is substantially increased by administration of cyclosporine A, a non-specific efflux-pump blocker. Ziółkowski, H, 2023) | 1.44 |
| " Interestingly, the bioavailability of the tetracyclines was around two times higher after orally administering cyclosporine A than after intravenously administering it (P < 0." | ( Bioavailability of tetracyclines is substantially increased by administration of cyclosporine A, a non-specific efflux-pump blocker. Ziółkowski, H, 2023) | 1.5 |
| "Copper (Cu) and tetracyclines (TCs) often coexist in agricultural soils because of the use of manures on farmland; however, the influence of Cu on the bioavailability of TCs is still unclear, especially for cases with aging Cu." | ( Influence of copper and aging on freely dissolved tetracycline concentration in soil. Guo, R; He, J; Li, L; Li, X; Ma, W; Wang, Y; Zhu, D, 2023) | 1.51 |
Doxycycline half-life significantly shorter in alcoholics than in controls. In some patients the serum concentration of doxycycline decreased below the generally accepted minimum therapeutic concentration when dosed once daily.
| Pathway | Proteins | Compounds |
|---|---|---|
| Tetracycline Action Pathway | 1 | 4 |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 10.7606 | 0.0013 | 10.1577 | 42.8575 | AID1259252; AID1259253; AID1259255; AID1259256 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 24.5412 | 0.0002 | 14.3764 | 60.0339 | AID720692 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 38.8952 | 0.0010 | 19.4141 | 70.9645 | AID743191 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 89.7625 | 0.0391 | 47.5451 | 146.8240 | AID1224845 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 (µMol) | 22.4474 | 0.1736 | 9.8032 | 29.2701 | AID712 |
| estrogen receptor beta isoform 1 | Homo sapiens (human) | IC50 (µMol) | 50.0000 | 1.9109 | 8.3165 | 18.7976 | AID1060 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 (µMol) | 22.4474 | 0.1736 | 9.8032 | 29.2701 | AID712 |
| tyrosine-protein phosphatase non-receptor type 7 isoform 2 | Homo sapiens (human) | IC50 (µMol) | 8.3300 | 0.1000 | 12.7265 | 63.0000 | AID521 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 (µMol) | 133.0000 | 0.6315 | 4.4531 | 9.3000 | AID1473740 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 (µMol) | 133.0000 | 0.2000 | 5.6774 | 10.0000 | AID1473741 |
| Bile salt export pump | Homo sapiens (human) | IC50 (µMol) | 134.0000 | 0.1100 | 7.1903 | 10.0000 | AID1443980; AID1473738 |
| 30S ribosomal protein S6 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S7 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L15 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 (µMol) | 140.0000 | 0.0000 | 1.2326 | 7.7930 | AID293953 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 (µMol) | 220.0000 | 0.0000 | 1.2848 | 10.0000 | AID293952 |
| Stromelysin-1 | Homo sapiens (human) | IC50 (µMol) | 140.0000 | 0.0000 | 1.1484 | 10.0000 | AID293953 |
| 50S ribosomal protein L10 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L11 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L7/L12 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L19 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L1 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L20 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L27 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L28 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L29 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L31 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L31 type B | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L32 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L33 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L34 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L35 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L36 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S10 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S11 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S12 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S13 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S16 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S18 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S19 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S20 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S2 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S3 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S4 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S5 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S8 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S9 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L13 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L14 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L16 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L23 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S15 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| Multidrug transporter MdfA | Escherichia coli K-12 | IC50 (µMol) | 13.2000 | 2.5000 | 2.5500 | 2.6000 | AID71156 |
| 50S ribosomal protein L17 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L21 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L30 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L6 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S14 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S17 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S1 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L18 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 (µMol) | 140.0000 | 0.0002 | 1.8742 | 10.0000 | AID293953 |
| Neutrophil collagenase | Homo sapiens (human) | IC50 (µMol) | 180.0000 | 0.0000 | 0.9272 | 10.0000 | AID293954 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 (µMol) | 180.0000 | 0.0002 | 1.2704 | 10.0000 | AID293954 |
| Alpha-synuclein | Homo sapiens (human) | IC50 (µMol) | 6.0600 | 0.1900 | 3.8204 | 9.8000 | AID1695730 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 (µMol) | 180.0000 | 0.0000 | 1.8194 | 10.0000 | AID293955 |
| Collagenase 3 | Homo sapiens (human) | IC50 (µMol) | 180.0000 | 0.0000 | 0.7675 | 10.0000 | AID293955 |
| Cannabinoid receptor 1 | Mus musculus (house mouse) | IC50 (µMol) | 180.0000 | 0.0030 | 0.9294 | 3.2000 | AID293954 |
| 50S ribosomal protein L2 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L3 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L24 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L4 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L22 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L5 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 30S ribosomal protein S21 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L25 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| 50S ribosomal protein L36 2 | Escherichia coli K-12 | IC50 (µMol) | 4.5800 | 0.0089 | 1.2035 | 5.0000 | AID646205 |
| Integrase | Human immunodeficiency virus 1 | IC50 (µMol) | 196.0000 | 0.0005 | 1.5443 | 10.0000 | AID307121; AID307122 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 (µMol) | 133.0000 | 2.4100 | 6.3433 | 10.0000 | AID1473739 |
| P2Y purinoceptor 12 | Homo sapiens (human) | Ki | 10.0000 | 0.0020 | 2.8220 | 9.8300 | AID375433 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 (µMol) | 780.0000 | 2.5000 | 4.2000 | 5.9000 | AID320706 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Solute carrier family 22 member 8 | Homo sapiens (human) | Km | 566.2000 | 0.3450 | 1.3217 | 3.1000 | AID681031 |
| Solute carrier family 22 member 11 | Homo sapiens (human) | Km | 122.7000 | 0.1540 | 0.6215 | 1.0100 | AID680162 |
| Solute carrier family 22 member 7 | Homo sapiens (human) | Km | 439.9000 | 0.4250 | 0.5690 | 0.7130 | AID680772 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1347170 | Vero cells viability counterscreen for qRT-PCR qHTS assay of selected Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347172 | Secondary qRT-PCR qHTS assay for selected Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347411 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7 | High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID547516 | Antimicrobial activity against Streptococcus anginosus obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of 5% defrib | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID543342 | Antimicrobial activity against Vibrio cholerae non-O1 assessed as percent tetracyclin-resistant isolate at 0.12 to 16 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID308345 | Antibacterial activity against Staphylococcus aureus MTCCB 96 | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID556891 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 3 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID585867 | Antimicrobial activity against Pseudomonas aeruginosa isolate 14 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1514478 | Antibacterial activity against Escherichia coli after 24 hrs | 2018 | Bioorganic & medicinal chemistry, 12-15, Volume: 26, Issue:23-24 | Isolation and structure determination of a new lasso peptide specialicin based on genome mining. |
| AID565002 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1412152 | Antibacterial activity against Pseudomonas aeruginosa isolate 1 after 24 hrs by microbroth dilution method | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID476289 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Poly(ethylene glycol) (PEG-400) as an alternative reaction solvent for the synthesis of some new 1-(4-(4'-chlorophenyl)-2-thiazolyl)-3-aryl-5-(2-butyl-4-chloro-1H-imidazol-5yl)-2-pyrazolines and their in vitro antimicrobial evaluation. |
| AID560781 | Antibacterial activity against Staphylococcus aureus TS10007 harboring ddlA Asp39Asn mutation in fifth-instar silkworm larva infection model assessed as compound concentration per gram of larva causing reduction in survival after 48 hrs post dose at 27 de | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID283169 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL5258 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID721792 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus 8325-4 assessed as growth inhibition after 24 hrs by CLSI broth microdilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. |
| AID287377 | Antibacterial activity against Mycobacterium smegmatis after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID556698 | Antimicrobial activity against multidrug resistant Escherichia coli ATCC 35218 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1058229 | Antibacterial activity against Bacillus cereus by CLSI method | 2013 | Bioorganic & medicinal chemistry, Dec-15, Volume: 21, Issue:24 | Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis. |
| AID1906417 | Antibacterial activity against imipenem resistant Klebsiella pneumoniae ATCC BAA 1705 assessed as reduction in microbial growth incubated for 24 hrs by microbroth dilution method | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Amphiphilic cyclic peptide [W |
| AID285195 | Antimicrobial activity against Escherichia coli M073 mutant with AG100 lon2::IS186 acrR::IS5 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID602692 | Binding affinity to bone mineral hydroxyapatite assessed as binding index after 0.5 hrs by UV-spectrophotometer analysis relative to 5-fluorouracil | 2011 | Bioorganic & medicinal chemistry, Jun-15, Volume: 19, Issue:12 | Selective bone targeting 5-fluorouracil prodrugs: synthesis and preliminary biological evaluation. |
| AID388003 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by microdilution broth method | 2008 | Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22 | Structure-activity relationship of antibacterial chalcones. |
| AID560223 | Antibacterial activity against Salmonella enterica serovar Typhimurium R200 expressing Outer membrane protein STM3031 by CLSI M7-A7 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Outer membrane protein STM3031 (Ail/OmpX-like protein) plays a key role in the ceftriaxone resistance of Salmonella enterica serovar Typhimurium. |
| AID1442633 | Antibacterial activity against gram-negative Pseudomonas aeruginosa PA555 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID556878 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 18 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID681044 | TP_TRANSPORTER: inhibition of E1S uptake (E1S: 0.05 uM, Tetracycline: 50 uM) in OAT3-expressing S2 cells | 2002 | Japanese journal of pharmacology, Jan, Volume: 88, Issue:1 | Human organic anion transporters mediate the transport of tetracycline. |
| AID516169 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as resistant isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID477103 | Antimicrobial activity against Serratia marcescens MTCC 86 at 10 ug/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID369445 | Antibacterial activity against penicillin-resistant Streptococcus pneumoniae after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID87951 | Minimum inhibitory concentration against Helicobacter pylori (Helicobacter pylori) ARHp strain 206 | 2002 | Journal of medicinal chemistry, Sep-12, Volume: 45, Issue:19 | Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 2. |
| AID1698037 | Antibacterial activity against Bacillus cereus assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID528923 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae expressing beta-lactamase CTX-M-14 and CTX-M-27 gene and other bla gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID519138 | Antimicrobial activity against community-acquired methicillin resistant Staphylococcus aureus expressing PVL and mec type IV gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. |
| AID614080 | Antibacterial activity against Bacillus brevis ATTC 9999 at 10 mg/ml after 24 to 72 hrs by agar diffusion method | 2011 | Bioorganic & medicinal chemistry, Sep-01, Volume: 19, Issue:17 | Synthesis and antimicrobial activity of (E) stilbene derivatives. |
| AID278270 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS38 acrAB::Kan with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID694393 | Bactericidal activity against Enterococcus faecalis CECT 481 at 0.2 mg/disk after 24 hrs by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones. |
| AID325019 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 981 isolate with erm(B) resistance gene from patient blood by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID460628 | Antifungal activity against Aspergillus flavus MTCC 2501 at 100 ug/ml after 48 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID1496310 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 368 after 24 hrs | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID341061 | Activity of tetracycline efflux transporter TetA(B) Asp190Cys mutant in Escherichia coli DH5alpha membrane vesicles assessed as [3H]tetracycline uptake | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate. |
| AID528724 | Antibacterial activity against Streptococcus oralis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID588212 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID428268 | Antimicrobial activity against carbapenemase producing Enterobacteriaceae assessed as resistant isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID1585464 | Antibacterial activity against linezolid-resistant Staphylococcus aureus NRS-271 measured after 16 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents. |
| AID521802 | Antimicrobial activity against Francisella tularensis subsp. tularensis after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | In vitro susceptibility of isolates of Francisella tularensis types A and B from North America. |
| AID532764 | Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing ramA::aph-pTRC hisA:ramA mutant by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. |
| AID1231526 | Antibacterial activity against Salmonella typhi CECT 409 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter broth dilution method | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antibacterial activities of cadiolides A, B and C and analogues. |
| AID447071 | Antibacterial activity against Escherichia coli ATCC 11230 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID447076 | Antibacterial activity against Proteus vulgaris ATCC 8427 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID1240028 | Antibacterial activity against Escherichia coli MTCC 724 after 24 hrs by microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID528708 | Antibacterial activity against multidrug-resistant Streptococcus pneumoniae clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID430969 | Antibacterial activity against tetracycline-susceptible Streptococcus pneumoniae GMRS06 harboring one-nucleotide insertion stop codon in tete(M) gene | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | The macrolide resistance genes erm(B) and mef(E) are carried by Tn2010 in dual-gene Streptococcus pneumoniae isolates belonging to clonal complex CC271. |
| AID529161 | FIC index, ratio of MIC for Pseudomonas aeruginosa 100609 in presence of 250 ug/ml polyethylenimine to MIC for Pseudomonas aeruginosa 100609 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID1079947 | Comments (NB not yet translated). [column 'COMMENTAIRES' in source] | |||
| AID560776 | Antibacterial activity against Staphylococcus aureus TS2921 harboring ddlA Asp102Asn mutation and coexpressing pSddlA which complements temperature sensitivity after 20 hrs | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID532987 | Antibacterial activity against Pseudomonas aeruginosa NCIM 5029 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID562239 | Antimycobacterial activity against Mycobacterium smegmatis by GFP-based fluorescence assay | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria. |
| AID544009 | Antimicrobial activity against Providencia stuartii isolate C167 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID678717 | Inhibition of human CYP3A4 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 7-benzyloxyquinoline as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID325029 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 376 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID406623 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae isolates assessed as percent resistant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Prevalence, characteristics, and molecular epidemiology of macrolide and fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae at five tertiary-care hospitals in Korea. |
| AID569038 | Antibacterial activity against Escherichia coli after 24 hrs micro dilution assay | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis, antimicrobial activity and structure-activity relationship study of N,N-dibenzyl-cyclohexane-1,2-diamine derivatives. |
| AID557082 | Antimicrobial activity against multidrug resistant Escherichia coli ATCC 35218 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID646212 | Antibacterial activity against tetracycline-resistant Streptococcus pneumoniae 160 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID535769 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID565073 | Antibacterial activity against CTX-M-14 ESBL producing Morganella morganii assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID323015 | Antibacterial activity against drug-resistant Propionibacterium acnes P322:2 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID587839 | Antibacterial activity against Staphylococcus aureus by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID322994 | Antibacterial activity against drug-resistant Propionibacterium acnes OK8/97 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1821107 | Antibacterial activity against Enterococcus faecium ATCC 19434 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID396279 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(D), tet(E) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID535771 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H carrying the luxAB gene under the hsp60 promoter agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID557792 | Antimicrobial activity against Streptococcus pyogenes clinical isolate expressing mosaic variant of mef gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Characterization of macrolide efflux pump mef subclasses detected in clinical isolates of Streptococcus pyogenes isolated between 1999 and 2005. |
| AID1055421 | Antibacterial activity against multidrug and methicillin-resistant Staphylococcus aureus 25697 assessed as growth inhibition by broth microdilution method | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Inducing secondary metabolite production by the endophytic fungus Fusarium tricinctum through coculture with Bacillus subtilis. |
| AID646356 | Oral bioavailability in human | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID312014 | Antibacterial activity against Bacillus cereus at 10 ug/disc after 48 hrs by disc diffusion assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae. |
| AID585427 | Antimicrobial activity against oqxAB positive Escherichia coli C600 XT11-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID531336 | Antibacterial activity against MeXAB-OprM deficient Pseudomonas aeruginosa TNP077 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID575944 | Antimicrobial activity against erythromycin-resistant Streptococcus pneumoniae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates. |
| AID585862 | Antimicrobial activity against Pseudomonas aeruginosa isolate 11 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID587841 | Antibacterial activity against Haemophilus influenzae by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID278593 | Reduced apicoplast DNA/nuclear DNA ratio in Plasmodium falciparum FCK2 at 100 uM after 72 hrs by competitive PCR | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID587833 | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID71156 | Inhibition of [3H]tetracycline uptake into everted membrane vesicles, prepared from tetracycline resistant Escherichia coli D1-209 | 1993 | Journal of medicinal chemistry, Feb-05, Volume: 36, Issue:3 | Inhibition of the tetracycline efflux antiport protein by 13-thio-substituted 5-hydroxy-6-deoxytetracyclines. |
| AID287376 | Antibacterial activity against Proteus vulgaris after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID278580 | Inhibition of Plasmodium falciparum FCK2 second cycle growth in erythrocytes at 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID534340 | Antimicrobial activity against Burkholderia pseudomallei Bp50 harboring deleted (amrRAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID1585459 | Antibacterial activity against Staphylococcus aureus Newman measured after 16 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents. |
| AID250261 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH05; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID372895 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by MTT assay | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. |
| AID1726840 | Synergistic antibacterial activity against Staphylococcus aureus assessed as tetracyclin MIC encapsulated by compound | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6 | Sulfonium-based liposome-encapsulated antibiotics deliver a synergistic antibacterial activity. |
| AID671694 | Oral bioavailability in human | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID548737 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID534344 | Antimicrobial activity against Burkholderia pseudomallei Bp174 harboring mini-Tn7T-bpeR+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID212903 | Inhibition of human telomerase before assembly using recombinant hTR and hTERT at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID396027 | Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump in presence of 20 ug/ml efflux pump inhibitor Phe-Arg-beta-naphthylamide by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID574168 | Antibacterial activity against Escherichia coli MG1655 grown as biofilms after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID564820 | Bactericidal activity against methicillin-susceptible Staphylococcus aureus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID575058 | Antibacterial activity against Escherichia coli JM109 harboring plasmid ptac85-vca0421 | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Reduced expression of the vca0421 gene of Vibrio cholerae O1 results in innate resistance to ciprofloxacin. |
| AID212902 | Inhibition of human telomerase after assembly using recombinant hTR and hTERT at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID554648 | Antimicrobial activity against Ureaplasma urealyticum isolate HPA3 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID1304854 | Aqueous solubility of compound in media after 16 hrs | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID285845 | Antimicrobial activity against tetracycline-susceptible Streptococcus pyogenes cMLS isolate G expressing tnpA, tnpR gene | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID528722 | Antibacterial activity against Streptococcus viridans clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID564817 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus hominis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID565315 | Antibacterial activity against Mycoplasma genitalium TW48-5G by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID1879068 | Antibacterial activity against NDM-1 positive Escherichia coli ZC-YN3 isolates assessed as inhibition of bacterial growth incubated for 18 to 24 hrs by CLSI based broth microdilution method | 2022 | European journal of medicinal chemistry, Mar-05, Volume: 231 | Metallo-β-lactamases inhibitor fisetin attenuates meropenem resistance in NDM-1-producing Escherichia coli. |
| AID546618 | Antimicrobial activity against Pseudomonas aeruginosa isolate 243-31C expressing beta-lactamase VIM-18 isolated from sputum of patient by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID585429 | Antimicrobial activity against Escherichia coli C600 ST2-T transconjugant harboring oqxAB, qnrB6 and aac(6')-Ib-cr genes by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID574178 | Antibacterial activity against Escherichia coli MG1655 grown as biofilms assessed as inhibition of bacterial biofilms formation at 5 to 500 ug/ml | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID404304 | Effect on human MRP2-mediated estradiol-17-beta-glucuronide transport in Sf9 cells inverted membrane vesicles relative to control | 2008 | Journal of medicinal chemistry, Jun-12, Volume: 51, Issue:11 | Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). |
| AID560054 | Antibacterial activity against Acinetobacter baumannii A9844 infected in Galleria mellonella caterpillar assessed as prolonged survival rate at 50 mg/kg administered as single dose | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Galleria mellonella as a model system to study Acinetobacter baumannii pathogenesis and therapeutics. |
| AID323903 | Antibacterial activity against wild type Staphylococcus aureus RN4220 | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID404935 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus isolate by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID556670 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 25 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID587834 | Antibacterial activity against tetracycline-resistant Streptococcus pneumoniae isolate 160 harboring tet(M) gene by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID534402 | Antibacterial activity against Escherichia coli EPI300 expressing tet(40) gene assessed as inhibition of bacterial growth at 40 ug/ml after 18 hrs in presence of 2.5 ug/ml efflux pump inhibitor CCCP | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones. |
| AID278669 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 2514 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID671552 | Antibacterial activity against tetracycline-resistant Streptococcus pneumoniae isolate 160 expressing tetM gene | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID432804 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus COL at 37 degC by population analysis method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Role of a sodium-dependent symporter homologue in the thermosensitivity of beta-lactam antibiotic resistance and cell wall composition in Staphylococcus aureus. |
| AID717274 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 by CLSI protocol based broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. |
| AID572060 | Antibacterial activity against abeS-deficient Acinetobacter baumannii AC0037 by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii. |
| AID1688649 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as reduction in bacterial growth incubated for 1 day by paper disk diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID564808 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID559342 | Antimicrobial activity against Shigella flexneri harboring tetG gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID495752 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow and treated with Cefixime by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID1382191 | Antibacterial activity against Salmonella typhi after 24 hrs by broth microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Synthesis of coumarin-theophylline hybrids as a new class of anti-tubercular and anti-microbial agents. |
| AID571882 | Antibacterial activity against Escherichia coli KAM32 harboring plasmid pUC18 by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii. |
| AID585852 | Antimicrobial activity against Pseudomonas aeruginosa isolate 6 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID524651 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ and mtrR mutant gene assessed as incidence of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID278576 | Inhibition of Plasmodium falciparum FCK2 growth as [3H]hypoxanthine uptake after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID396273 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(A), tet(E) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID396503 | Antibacterial activity against tetracycline-susceptible Escherichia coli clinical isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID556861 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 1 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565012 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID285842 | Antimicrobial activity against tetracycline-susceptible Streptococcus pyogenes cMLS isolate D expressing tet(M), Xis, tnpA, tnpR gene | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID530346 | Antimicrobial activity against azide-resistant Escherichia coli J53 harboring pCTX-M plasmid carrying blaCTX-M-15 gene by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID561513 | Antibacterial activity against Beta-hemolytic Streptococcus group B by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID1079948 | Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source] | |||
| AID1688647 | Antifungal activity against Aspergillus brasiliensis ATCC 16404 assessed as diameter of inhibition zone at 0.5 mg/ml incubated for 72 hrs by agar diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID554865 | Antimicrobial activity against Streptococcus pneumoniae serotype 19F ST 2694 harboring ERY-resistant mef(E) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID531630 | Antimicrobial activity against Ureaplasma urealyticum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. |
| AID572595 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium 902SA92 harboring GyrA S83A and D87N, GyrB S464F and ParC S80I mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1061189 | Antimicrobial activity against Klebsiella pneumoniae MTCC 3384 at 50 ug/ml after 24 hrs by disc diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID489652 | Antibacterial activity against Staphylococcus epidermidis ATCC 14990 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID323915 | Antibacterial activity against Staphylococcus aureus 2A1-7 with rplC G152D, D159Y and unmapped mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID561109 | Antibacterial activity against Pasteurella multocida BB1043 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID565290 | Antimicrobial activity against Mycoplasma pneumoniae by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | In vitro activity of a new quinoline derivative, ER-2, against clinical isolates of Mycoplasma pneumoniae and Mycoplasma hominis. |
| AID1231530 | Antibacterial activity against Escherichia coli CECT 100 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter broth dilution method | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antibacterial activities of cadiolides A, B and C and analogues. |
| AID1061177 | Antimicrobial activity against Staphylococcus aureus MTCC 96 after 24 hrs by microdilution method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID71055 | Compound was tested for photoinhibition of Escherichia coli (CIP 548T); Sensitive | 1998 | Bioorganic & medicinal chemistry letters, Nov-03, Volume: 8, Issue:21 | Nitroglycosylated meso-arylporphyrins as photoinhibitors of gram positive bacteria. |
| AID1634997 | Antifungal activity against Candida albicans assessed as reduction in fungal growth after 20 hrs by drop diffusion test | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID559593 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutY mutant gene selected in presence of Ceftazidime by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID1335593 | Antibacterial activity against methicillin resistant Staphylococcus aureus MFBF 10682 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID404937 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus sp. by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID445446 | Oral bioavailability in human | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability. |
| AID587243 | Antimicrobial activity against Klebsiella pneumoniae DSM 681 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID369447 | Antimicrobial activity against Streptococcus group B after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID554649 | Antimicrobial activity against Ureaplasma urealyticum isolate HPA6 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID1688657 | Bactericidal activity against Salmonella typhi ATCC 6539 incubated for 24 hrs followed by transferring to freshly prepared broth medium and measured after 24 hrs by broth microdilution assay | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID520393 | Antibacterial activity against mef-positive Streptococcus pneumoniae isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID587847 | Oral bioavailability in Sprague-Dawley rat at 1 mg/kg, iv and 10 mg/kg, po | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID529554 | Antimicrobial activity against Bacillus anthracis MurA1 AS clone 2G2 assessed as growth inhibition in presence of xylose by antisense-induced hypersensitive testing | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Comparison of the essential cellular functions of the two murA genes of Bacillus anthracis. |
| AID417535 | Antibacterial activity against Staphylococcus aureus after 24 hrs by NLCCS microdilution method | 2009 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 19, Issue:5 | Synthesis and antibacterial activity evaluation of metronidazole-triazole conjugates. |
| AID574547 | Increase in PSMalpha levels in Staphylococcus aureus USA300 at subinhibitory concentrations after 24 hrs by RP-HPLC/ESI- MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID444054 | Oral bioavailability in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID524654 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing tetM mutant gene in combination with variants of other gene loci assessed as incidence of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID1159086 | Antimicrobial activity against Klebsiella pneumoniae ATCC 13882 assessed as zone of inhibition at 30 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID544276 | Antimicrobial activity against Enterococcus faecalis NKH6 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID348889 | Antibacterial activity against Escherichia coli ATCC 25922 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID516166 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as susceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID1067610 | Inhibition of thioflavin T binding to human amylin assessed as half life | 2013 | Journal of medicinal chemistry, Aug-08, Volume: 56, Issue:15 | A new face for old antibiotics: tetracyclines in treatment of amyloidoses. |
| AID1431167 | Antibacterial activity against linezolid-resistant Staphylococcus aureus NRS-271 containing phage type E-MRSA after 18 hrs by two fold serial dilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: modifications at C12 and C7. |
| AID56762 | Inhibition zone when tested against DAP-AT from Escherichia coli in M9-Minimal agar at concentration 0.3 ug | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8 | Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. |
| AID1061187 | Antimicrobial activity against Klebsiella pneumoniae MTCC 3384 at 100 ug/ml after 24 hrs by disc diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID460622 | Antibacterial activity against Escherichia coli MTCC 1650 at 50 ug/ml after 24 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID369659 | Antibacterial activity against Campylobacter jejuni 25-45 cmeB:: Kanamycin-resistant mutant by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID1061175 | Antimicrobial activity against Klebsiella pneumoniae MTCC 3384 after 24 hrs by microdilution method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID325446 | Antibacterial activity against Salmonella enterica serovar Typhimurium LT2 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID1304848 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate 2 incubated for 16 hrs by broth microdilution method in presence of Cu2+ | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID541176 | Antimicrobial activity against multidrug resistant Streptococcus pneumoniae serotype 19F S43 carring erm(B),mef(E) and tet(M) gene | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | New composite genetic element of the Tn916 family with dual macrolide resistance genes in a Streptococcus pneumoniae isolate belonging to clonal complex 271. |
| AID544026 | Antimicrobial activity against Acinetobacter lwoffii isolate C37 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID404950 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus sp. assessed as percent susceptible isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID1304861 | Dissociation constant, pKa of compound | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID1442632 | Antibacterial activity against gram-negative Proteus mirabilis PM385 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID613192 | Antibacterial activity against Streptococcus pyogenes ATCC 19615 after 24 hrs by MTT assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives. |
| AID1698044 | Antibacterial activity against Salmonella abony assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID594336 | Antimicrobial activity against Escherichia coli NCIM 2068/ATCC 11105 at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID528723 | Antibacterial activity against Streptococcus constellatus clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID1055418 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as growth inhibition by broth microdilution method | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Inducing secondary metabolite production by the endophytic fungus Fusarium tricinctum through coculture with Bacillus subtilis. |
| AID554660 | Antimicrobial activity against Ureaplasma parvum SV9 containing tetM gene | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID1158047 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as compound level causing less than 2% growth after 16 hrs by serial dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla. |
| AID1514477 | Antibacterial activity against Micrococcus luteus after 24 hrs | 2018 | Bioorganic & medicinal chemistry, 12-15, Volume: 26, Issue:23-24 | Isolation and structure determination of a new lasso peptide specialicin based on genome mining. |
| AID1149695 | Antimicrobial activity against Escherichia coli assessed as growth inhibition at 0.78 ug/ml after 24 hrs by two-fold serial dilution technique | 1977 | Journal of medicinal chemistry, Jun, Volume: 20, Issue:6 | Synthesis of 5-chloro-3'-nitro-4'-substituted salicylanilides, a new series of anthelmintic and antimicrobial agents. |
| AID1335596 | Antibacterial activity against vancomycin resistant Enterococcus faecalis MFBF 11419 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID1348086 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 assessed as zone of inhibition at 50 ug per disc after 24 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID522669 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis B133 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID565638 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.10 ug/ml (Rvb =757.5 +/- 80.14 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1412156 | Bactericidal activity against methicillin-resistant Staphylococcus epidermidis 57 incubated for 24 hrs followed by replating on Mueller hinton agar plates and measured after 24 hrs | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID564830 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID428267 | Antimicrobial activity against carbapenemase producing Enterobacteriaceae assessed as susceptible isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID1079937 | Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source] | |||
| AID428269 | Antimicrobial activity against Klebsiella sp. by CLSI broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID283660 | Antimicrobial activity against Haemophilus influenzae CDS23 mutant overexpressing Def by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number. |
| AID544285 | Antimicrobial activity against Enterococcus faecalis NKH15 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1131163 | Antibacterial activity against Staphylococcus aureus MB2865 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID564805 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID560778 | Antibacterial activity against Staphylococcus aureus RN4220 in fifth-instar silkworm larva infection model assessed as compound concentration per gram of larva causing reduction in survival after 48 hrs post dose at 27 degC | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID1228692 | Antibacterial activity against tet(B) tetracycline-resistant Acinetobacter baumannii 250 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID65059 | Concentration required for half maximum rate of enhanced [3H]DHS uptake in Escherichia coli K12 | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID212742 | Inhibition of purified telomerase of Euplotes aediculatus at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID565308 | Antibacterial activity against Mycoplasma genitalium by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID535636 | Antimicrobial activity against Group B streptococcus serotype VI R4 harboring Q557E mutation in PBP 2X and T567I, Y262N mutations in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID588216 | FDA HLAED, serum glutamic oxaloacetic transaminase (SGOT) increase | 2004 | Current drug discovery technologies, Dec, Volume: 1, Issue:4 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. |
| AID646354 | AUClast in Sprague-Dawley rat at 10 mg/kg, po by LC/MS-MS analysis | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID396498 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(A), tet(B), tet(D), tet(E) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID548522 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID564822 | Bactericidal activity against methicillin-resistant Staphylococcus aureus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID445445 | Permeability at pH 6.5 by PAMPA method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability. |
| AID1428626 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 by broth microdilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. |
| AID572786 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium BN10055 harboring GyrA S83Y mutant gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID520965 | Antimicrobial activity against Listeria monocytogenes isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID1688651 | Antibacterial activity against Salmonella typhi ATCC 6539 assessed as reduction in bacterial growth incubated for 1 day by paper disk diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID1634996 | Hemolytic activity in human type RBC after 1 hr | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID524884 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ and mtrR mutant gene assessed as incidence of resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID544274 | Antimicrobial activity against Enterococcus faecalis NKH4 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID584122 | Antimicrobial activity against Staphylococcus aureus RN4220 by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID572791 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium BN9945 harboring plasmid encoded RamR gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1058228 | Antibacterial activity against Escherichia coli ATCC 29522 by CLSI method | 2013 | Bioorganic & medicinal chemistry, Dec-15, Volume: 21, Issue:24 | Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis. |
| AID294965 | Antibacterial activity against Escherichia coli ATCC 23556 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID1228689 | Antibacterial activity against Proteus mirabilis 385 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID543354 | Antimicrobial activity against Salmonella serogroup O9 assessed as percent tetracyclin-resistant isolate at 1 to >128 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID428429 | Antibacterial activity against Salmonella typhi after 24 hrs by well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of novel carbazole based macrocyclic amides as potential antimicrobial agents. |
| AID1079939 | Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source] | |||
| AID565069 | Antibacterial activity against SHV-12 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID283558 | Antibacterial activity against Escherichia coli AG102 with marR1 mutation after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. |
| AID543356 | Antimicrobial activity against Salmonella serotype Typhimurium by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID649517 | Antimicrobial activity against epidemic methicillin-resistant Staphylococcus aureus 15 after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry, Mar-15, Volume: 20, Issue:6 | Efficient synthesis and biological evaluation of proximicins A, B and C. |
| AID1587192 | Antibacterial activity against Staphylococcus aureus assessed as diameter of zone inhibition at 100 ppm by disc diffusion method | 2019 | European journal of medicinal chemistry, May-15, Volume: 170 | 4(3H)-Quinazolinone derivatives: Promising antibacterial drug leads. |
| AID1240025 | Antibacterial activity against Bacillus cereus MTCC 8372 assessed as concentration required to completely destroy test microorganisms after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID494533 | Antimicrobial activity against Staphylococcus aureus NCIM 5021 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494533 | Antimicrobial activity against Staphylococcus aureus NCIM 5021 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID1577571 | Antibacterial activity against Clostridium perfringens assessed as inhibition of bacterial growth after 24 hrs by microdilution method | |||
| AID388004 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by microdilution broth method | 2008 | Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22 | Structure-activity relationship of antibacterial chalcones. |
| AID448517 | Antimicrobial activity against Escherichia coli MTCCB 1652 after 24 hrs by serial dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents. |
| AID1617789 | Antibacterial activity against Escherichia coli ATCC 25922 incubated for 24 hrs by broth microdilution method | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12 | Structural Characterization and Anti-infective Activity of 9,10-Seco-29-norcycloartane Glycosides Isolated from the Flowers of the Peruvian Medicinal Plant |
| AID556700 | Antimicrobial activity against multidrug resistant Escherichia coli ATCC 35218 harboring pDrive plasmid expressing ampC gene by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID278856 | Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID322991 | Antibacterial activity against drug-resistant Propionibacterium acnes SW17 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID522824 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis NH by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID544058 | Antimicrobial activity against Shigella flexneri isolate C506 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID562812 | Antimicrobial activity against Escherichia coli DH5[alpha] | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID1079936 | Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source] | |||
| AID559327 | Antimicrobial activity against Salmonella enterica serovar Infantis assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID1366158 | Antibacterial activity against Escherichia coli incubated overnight by two-fold serial dilution method | 2017 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22 | Antibacterial constituents of the plant family Amaryllidaceae. |
| AID325447 | Antibacterial activity against Staphylococcus aureus N315 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID563510 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens HMS011 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID237474 | Percentage of drug bound in bovine plasma albumin | 2004 | Journal of medicinal chemistry, Jul-29, Volume: 47, Issue:16 | Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction. |
| AID423156 | Antibacterial activity against Lactobacillus johnsonii L0077 by Etest | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Mosaic tetracycline resistance genes and their flanking regions in Bifidobacterium thermophilum and Lactobacillus johnsonii. |
| AID561727 | Antibacterial activity against Enterococcus faecium assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID283172 | Effect on biofilm formation of Staphylococcus lugdunensis assessed as percent non-biofilm forming isolates | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID531626 | Antimicrobial activity against Mycoplasma genitalium by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. |
| AID283161 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2588 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID532219 | Antibacterial activity against macrolide-lincosamide-streptogramin B-negative, beta-lactamase-positive, methicillin-susceptible Staphylococcus aureus isolate 4 | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Combined antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone-spermine conjugate. |
| AID535643 | Antimicrobial activity against Group B streptococcus serotype III N3 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID565005 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID585430 | Antimicrobial activity against oqxAB positive Escherichia coli C600 SP8-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID528703 | Antibacterial activity against Streptococcus oralis clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID649519 | Antimicrobial activity against Escherichia coli NCTC 10418 after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry, Mar-15, Volume: 20, Issue:6 | Efficient synthesis and biological evaluation of proximicins A, B and C. |
| AID530585 | Antimicrobial activity against Mycoplasma pneumoniae isolate 19 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID565061 | Antibacterial activity against wild-type Escherichia coli AG100 at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1681009 | Antibacterial activity against Staphylococcus aureus assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID629282 | Antibacterial activity against Photobacterium leiognathi Sh1 assessed as inhibition of bacterial luminescence at 0.25 mg/mL after 10 mins by bioluminometry-based acute action test | 2011 | European journal of medicinal chemistry, Dec, Volume: 46, Issue:12 | Synthesis and biological activity of novel N-cycloalkyl-(cycloalkylaryl)-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-yl)thio]acetamides. |
| AID1127618 | Antibacterial activity against fluoroquinolone-resistant Streptococcus pneumoniae D39 NCTC 7466 expressing GyrB/ParE T172A mutant assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID678716 | Inhibition of human CYP3A4 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using diethoxyfluorescein as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID529894 | Antimicrobial activity against Leptospira interrogans serovar Grippotyphosa isolate 2 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID564815 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1428348 | Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay | 2016 | Journal of natural products, Dec-23, Volume: 79, Issue:12 | Antimicrobial Oligophenalenone Dimers from the Soil Fungus Talaromyces stipitatus. |
| AID565060 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID520394 | Antibacterial activity against mef(E)-positive Streptococcus pneumoniae isolate Spain 9V-3 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID548796 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID564833 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID561640 | Antibacterial activity against Escherichia coli by CLSI M100-S13 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Pyrazolopyrimidinediones are selective agents for Helicobacter pylori that suppress growth through inhibition of glutamate racemase (MurI). |
| AID584828 | Antibacterial activity against Klebsiella pneumoniae | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Chip calorimetry for fast and reliable evaluation of bactericidal and bacteriostatic treatments of biofilms. |
| AID1473739 | Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 20 mins by membrane vesicle transport assay | 2013 | Toxicological sciences : an official journal of the Society of Toxicology, Nov, Volume: 136, Issue:1 | A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. |
| AID541857 | Antimicrobial activity against Escherichia coli ATCC 29522 carrying Edwardsiella ictaluri pM07-1 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID1182956 | Antibacterial activity against Escherichia coli ATCC 25922 by broth microdilution method | 2014 | Journal of natural products, Jul-25, Volume: 77, Issue:7 | Trimeric anthracenes from the endophytic fungus Stemphylium globuliferum. |
| AID285156 | Antimicrobial activity against Streptococcus pneumoniae ATCC 49619 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland. |
| AID585875 | Antimicrobial activity against Pseudomonas aeruginosa isolate 18 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID528702 | Antibacterial activity against Streptococcus constellatus clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID548795 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID625290 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID278252 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS3 with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID529160 | Antibacterial activity against Pseudomonas aeruginosa 100609 after 20 hrs by broth microdilution assay in presence of 250 ug/ml polyethylenimine | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID530583 | Antimicrobial activity against macrolide-resistant Mycoplasma pneumoniae isolate 2p with A2604G mutation by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID1431162 | Antibacterial activity against Staphylococcus aureus Newman after 18 hrs by two fold serial dilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: modifications at C12 and C7. |
| AID396031 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pACYC184 plasmid by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID428138 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae isolate P1501016 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. |
| AID1496308 | Antibacterial activity against vancomycin-susceptible Enterococcus faecalis ATCC 29212 after 24 hrs | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID425601 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 10% compound Cmax a | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID516167 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as resistant isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID576109 | Antimicrobial activity against mecA-deficient Staphylococcus sciuri assessed as resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. |
| AID556872 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 12 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID283155 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL856 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID467967 | Antimicrobial activity against Staphylococcus aureus ATCC 12600 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID369443 | Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID1338322 | Antibacterial activity against Salmonella bongori PCM 2552 after 20 hrs by microbroth dilution method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | New family of antimicrobial agents derived from 1,4-naphthoquinone. |
| AID1698050 | Antibacterial activity against Shigella boydii assessed as inhibition of bacterial growth incubated for overnight by CLSI based method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID1428345 | Antibacterial activity against Staphylococcus haemolyticus MNHN26 after 24 hrs | 2016 | Journal of natural products, Dec-23, Volume: 79, Issue:12 | Antimicrobial Oligophenalenone Dimers from the Soil Fungus Talaromyces stipitatus. |
| AID572598 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium 102SA00 harboring GyrA S83A and D87N, GyrB S464F and ParC S80I mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID572599 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium BN10055 harboring GyrA S83Y mutant gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID522644 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis SK57 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID1424152 | Antibacterial activity Bacillus pumilus against by broth dilution assay | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Antibacterial Compounds from Marine Bacteria, 2010-2015. |
| AID554871 | Antimicrobial activity against Streptococcus pneumoniae serotype 6B ST 90 harboring ERY-resistant erm(B) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID646208 | Antibacterial activity against tetracycline-resistant Staphylococcus aureus 158 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID70764 | In vitro minimum inhibitory concentration against Escherichia coli UBMS 88-1 (tet B efflux). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID543358 | Antimicrobial activity against Salmonella serogroup O8 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID460800 | Antibacterial activity against Acinetobacter baumannii UH8407 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID484676 | Antibacterial activity against Salmonella typhi | 2010 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 20, Issue:12 | Synthesis of novel beta-lactam fused spiroisoxazolidine chromanones and tetralones as potent antimicrobial agent for human and plant pathogens. |
| AID556656 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 11 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID556675 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 2 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID324197 | Antibacterial activity against Escherichia coli K12 mutant JHU313 at 12.5 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID369230 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae assessed as percent sensitive isolates by CLSI breakpoint method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID501865 | Antifungal activity against Aspergillus fumigatus isolates after 48 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID585856 | Antimicrobial activity against Pseudomonas aeruginosa isolate 8 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID609168 | Antifungal activity against Candida glabrata assessed as zone of inhibition at 5 uL and 28 degC after 36 hrs by disk diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone. |
| AID646218 | Antibacterial activity against Klebsiella pneumoniae ATCC 109 13883 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID1231523 | Antibacterial activity against Bacillus cereus CECT 148 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter broth dilution method | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antibacterial activities of cadiolides A, B and C and analogues. |
| AID405455 | Antibacterial activity against Escherichia coli 1540 isolate by disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli. |
| AID1240014 | Antibacterial activity against Bacillus cereus MTCC 8372 at 100 ug/ml after 24 hrs by disc diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID283648 | Susceptibility of Escherichia coli K12 MG1655 in presence of 10 mM glutathione by agar dilution method relative to control | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID206120 | In vitro minimum inhibitory concentration against Staphylococcus aureus UBMS 90-1 (tet M ribosomal protection). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID556895 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 7 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1368274 | Antibacterial activity against Staphylococcus aureus RN4220 over-expressing FabI by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1 | A novel series of enoyl reductase inhibitors targeting the ESKAPE pathogens, Staphylococcus aureus and Acinetobacter baumannii. |
| AID1551778 | Antibacterial activity against Staphylococcus aureus assessed as zone of inhibition | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID561514 | Antibacterial activity against Enterococcus faecalis by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID565642 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.12 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =790.8 +/- 90.09 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID528793 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli expressing beta-lactamase CTX-M-3, CTX-M-15 and CTX-M-55 and other bla gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID531629 | Antimicrobial activity against Ureaplasma parvum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. |
| AID556874 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 14 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID456848 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by microdilution assay | 2010 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3 | Synthesis and antibacterial activity of benzyl-[3-(benzylamino-methyl)-cyclohexylmethyl]-amine derivatives. |
| AID1592959 | Antibacterial activity against multi-drug resistant Klebsiella pneumoniae NMI 2697/14 assessed as reduction in microbial growth incubated for 20 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. |
| AID565072 | Antibacterial activity against SHV-12 ESBL producing Klebsiella pneumoniae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID564812 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID564825 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1230064 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2272 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID557208 | Antibacterial activity against Beta-lactamase-negative Neisseria meningitidis by Etest method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. |
| AID535641 | Antimicrobial activity against Group B streptococcus serotype V C1 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID575057 | Antibacterial activity against Escherichia coli JM109 harboring plasmid ptac85 | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Reduced expression of the vca0421 gene of Vibrio cholerae O1 results in innate resistance to ciprofloxacin. |
| AID489646 | Antibacterial activity against Citrobacter freundii ATCC 27853 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID454479 | Antimicrobial activity against Aspergillus flavus MTCC 2501 at 10 ug/ml after 48 hrs by agar diffusion method | 2009 | Bioorganic & medicinal chemistry, Dec-15, Volume: 17, Issue:24 | Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents. |
| AID572817 | Antimicrobial activity against ramR::kan-deficient Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID564832 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus sciuri after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID278237 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-2 gyrA+ with ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID543357 | Antimicrobial activity against Salmonella serogroup O7 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID541148 | Antimicrobial activity against acrB::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 104-cip harboring gyrA D87Y,S83F mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID559596 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 selected in presence of tobramycin by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID1431164 | Antibacterial activity against erythromycin-resistant Staphylococcus aureus NRS-70 after 18 hrs by two fold serial dilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: modifications at C12 and C7. |
| AID1695730 | Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Toward the discovery and development of effective modulators of α-synuclein amyloid aggregation. |
| AID1392014 | Antistaphylococcal activity against linezolid-resistant Staphylococcus aureus NRS-271 containing phage type E-MRSA 15 after 18 hrs by two-fold serial dilution method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10 | The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid. |
| AID554857 | Antimicrobial activity against Streptococcus pneumoniae serotype 14 ST 2918 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID278261 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS14 gyrA+ with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID491945 | Antibacterial activity against Brevibacterium epidermidis DSM 20660 after 48 hrs by microtiter plate assay | 2010 | Journal of natural products, Jul-23, Volume: 73, Issue:7 | Mayamycin, a cytotoxic polyketide from a Streptomyces strain isolated from the marine sponge Halichondria panicea. |
| AID556898 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 10 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID516168 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as susceptible isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID575167 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in marR mutant containing Escherichia coli K-12 3-AG102 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 1000 uM by spectrofluorometric | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID443282 | Antimicrobial activity against Escherichia coli after 24 hrs by agar dilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Anti-oxidant and anti-bacterial activities of novel N'-arylmethylidene-2-(3, 4-dimethyl-5, 5-dioxidopyrazolo[4,3-c][1,2]benzothiazin-2(4H)-yl) acetohydrazides. |
| AID405081 | Antimicrobial activity against Escherichia coli CAG12177 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID556650 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 5 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1225257 | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 assessed as bacterial growth inhibition after 24 hrs by standard broth microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 25, Issue:1 | A potent antimicrobial compound isolated from Clathria cervicornis. |
| AID557081 | Antimicrobial activity against multidrug resistant Escherichia coli DH5[alpha] harboring pACM204 plasmid by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1382189 | Antibacterial activity against Staphylococcus aureus after 24 hrs by broth microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Synthesis of coumarin-theophylline hybrids as a new class of anti-tubercular and anti-microbial agents. |
| AID562238 | Antimycobacterial activity against Mycobacterium smegmatis assessed as growth inhibition in mid-logarithmic phase by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria. |
| AID601190 | Antimicrobial activity against tetracycline-susceptible Staphylococcus aureus Smith isolate 100 by CLSI dilution method | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID629286 | Antibacterial activity against Photobacterium leiognathi Sh1 assessed as inhibition of bacterial luminescence at 0.25 mg/mL after 10 mins by bioluminometry-based chronic action test | 2011 | European journal of medicinal chemistry, Dec, Volume: 46, Issue:12 | Synthesis and biological activity of novel N-cycloalkyl-(cycloalkylaryl)-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-yl)thio]acetamides. |
| AID520961 | Antimicrobial activity against Corynebacterium urealyticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID564811 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1061178 | Antimicrobial activity against Bacillus cereus MTCC 8372 after 24 hrs by microdilution method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID522652 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis 02AS-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID528922 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli expressing beta-lactamase CTX-M-14 and CTX-M-27 gene and other bla gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID556868 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 8 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID429057 | Antimicrobial activity against tetracycline-resistant Mycoplasma hominis isolate overexpressing tet(M) gene | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Tetracycline resistance in Ureaplasma spp. and Mycoplasma hominis: prevalence in Bordeaux, France, from 1999 to 2002 and description of two tet(M)-positive isolates of M. hominis susceptible to tetracyclines. |
| AID533660 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring plasmid VGA | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID540928 | Antimicrobial activity against streptomycin-resistant Streptomyces coelicolor KO-178 harboring rpsL K88E mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID524871 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea assessed as incidence of resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID572597 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium 102SA00 harboring plasmid encoded RamR gene, GyrA S83A and D87N, GyrB S464F and ParC S80I mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID522367 | Antimicrobial activity against PpmrI knockout mutant Proteus mirabilis dIpc complemented with PPmrI gene after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID567567 | Antimicrobial activity against Bacillus sp. BS-01 expressing multiple resistance gene cfr and phenolic resistance gene fexA obtained from swine feces | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID565639 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.12 ug/ml (Rvb =757.5 +/- 80.14 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID501851 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID404948 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus isolate assessed as susceptible resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID573967 | Antibacterial activity against Cj1211-negative Campylobacter jejuni harboring aphA3 and tet(O) genes | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of Cj1211 in natural transformation and transfer of antibiotic resistance determinants in Campylobacter jejuni. |
| AID587842 | Antibacterial activity against Escherichia coli by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID1689769 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 | 2020 | European journal of medicinal chemistry, Mar-01, Volume: 189 | Simple amphiphilic α-hydrazido acids: Rational design, synthesis, and in vitro bioactivity profile of a novel class of potential antimicrobial compounds. |
| AID535774 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H containing pCK0601 carrying the luxAB gene under the hsp60 promoter after 14 days determined according to RLU count by real-time luminescence method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID575169 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 1000 uM by spectrofluorometric assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID1225387 | Antibacterial activity against Escherichia coli AG102 overexpressing AcrAB-TolC by p-iodonitrotetrazolium chloride colorimetric assay | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Enhancement of antibiotic activity against multidrug-resistant bacteria by the efflux pump inhibitor 3,4-dibromopyrrole-2,5-dione isolated from a Pseudoalteromonas sp. |
| AID524661 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea assessed as percentage intermediate isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID533665 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID544022 | Antimicrobial activity against Psychrobacter frigidicola isolate C712 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID548528 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID278674 | Antibacterial activity against Enterococcus faecalis isolate 5744 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID585846 | Antimicrobial activity against Pseudomonas aeruginosa isolate 3 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID522658 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis V770-NP1-R by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID449365 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 at 30 ug/mL after 16 to 20 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety. |
| AID564891 | Antibacterial activity against ompF-deficient Escherichia coli AG100 at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1566496 | Binding affinity to miR-21 RNA in human HeLA cells transfected with pmirGLO empty vector incubated for 48 hrs by Dual-Glo luciferase assay | 2019 | ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5 | Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. |
| AID561342 | Antibacterial activity against Beta-hemolytic Streptococcus group A by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID565062 | Antibacterial activity against wild-type Escherichia coli AG100 at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID678715 | Inhibition of human CYP2D6 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 4-methylaminoethyl-7-methoxycoumarin as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID528729 | Antibacterial activity against multidrug-resistant Streptococcus pneumoniae clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID323916 | Antibacterial activity against Staphylococcus aureus 2A1-8 with rplC G152D, D159Y and unmapped mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID694395 | Bactericidal activity against Escherichia coli CECT 405 at 0.2 mg/disk after 24 hrs by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones. |
| AID325025 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 838 isolate with erm(B) and mef(E) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID1228685 | Antibacterial activity against tet(M) tetracycline-resistant Streptococcus pneumoniae 160 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID420020 | Antibacterial activity against Staphylococcus aureus at 20 mg/mL by agar diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Novel pyridazine derivatives: Synthesis and antimicrobial activity evaluation. |
| AID522663 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis SPS 0053 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID543355 | Antimicrobial activity against Salmonella serotype Choleraesuis by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID575054 | Antibacterial activity against Vibrio cholerae O1 569B harboring gyrA and parC genes by 2-fold agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Reduced expression of the vca0421 gene of Vibrio cholerae O1 results in innate resistance to ciprofloxacin. |
| AID308347 | Antibacterial activity against Escherichia coli | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID348886 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID278259 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS9 tolC::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID510749 | Antibacterial activity against Escherichia coli AG102MB harboring pP10-based acrB gene | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID561108 | Antibacterial activity against Pasteurella multocida BB1042 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID342018 | Antibacterial activity against Klebsiella pneumoniae NK29 by Etest | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae. |
| AID540210 | Clearance in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID1127619 | Antibacterial activity against fluoroquinolone-resistant Streptococcus pneumoniae D39 NCTC 7466 expressing GyrB T172A/ParE T172A double mutant assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID1231529 | Antibacterial activity against Bacillus subtilis CECT 35 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter broth dilution method | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antibacterial activities of cadiolides A, B and C and analogues. |
| AID1888846 | Antibacterial activity against Staphylococcus aureus 1199B measured after 24 hrs by Muller Hinton broth based MTT assay | 2022 | Bioorganic & medicinal chemistry, 01-15, Volume: 54 | Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor. |
| AID524825 | Antibacterial activity against erythromycin susceptible Campylobacter sp. by agar plate dilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID547517 | Antimicrobial activity against Streptococcus anginosus obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on brain heart infusion agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID545057 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate SZ009 from patient pus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID588213 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID396030 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pAP2 plasmid containing Enterobacter cloacae acrA gene by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID460626 | Antibacterial activity against Bacillus subtilis MTCC 1789 at 50 ug/ml after 24 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID1551812 | Antibacterial activity against Bacillus anthracis incubated for 18 hrs post 30 mins pre-diffusion by disk diffusion method | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID396499 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID563503 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 79 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID556657 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 12 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID531627 | Antimicrobial activity against Mycoplasma hominis by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. |
| AID528785 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli assessed as resistant isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID534401 | Antibacterial activity against Escherichia coli EPI300 harboring plasmid GEM-T expressing tet(40) gene after 16 hrs | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones. |
| AID644021 | Antimicrobial activity against Staphylococcus aureus at 100 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID1079944 | Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] | |||
| AID1392012 | Antistaphylococcal activity against oxacillin/tetracycline-resistant Staphylococcus aureus NRS-100 after 18 hrs by two-fold serial dilution method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10 | The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid. |
| AID528709 | Antibacterial activity against penicillin resistant Streptococcus pneumoniae clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID563508 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 79 harboring plasmid STV29 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID585426 | Antimicrobial activity against oqxAB positive Escherichia coli C600 X1B1-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID574175 | Antibacterial activity against Escherichia coli MG1655 harboring grown as biofilms plasmid pBR322 carrying blaTEM-1 and tetA(C) genes assessed as decrease in bacterial biofilms formation at 5 ug/ml by GFP assay | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID548525 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID278268 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS38 with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID562792 | Antimicrobial activity against Chlamydophila caviae GPIC/rifR harboring rpoB gene | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID765061 | Antimicrobial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. |
| AID556696 | Antimicrobial activity against multidrug resistant Escherichia coli DH5[alpha] harboring pDrive plasmid expressing ampC gene by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID567568 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring pBS-01multiple resistance gene cfr and phenolic resistance gene fexA obtained from swine feces | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID323014 | Antibacterial activity against drug-resistant Propionibacterium acnes QK6/92 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID425403 | Antibacterial activity Escherichia coli isolate HM419 isolated from ileo-colonic mucosal biopsies of patient with Crohn's disease after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID278858 | Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID1240018 | Antibacterial activity against Escherichia coli MTCC 724 at 100 ug/ml after 24 hrs by disc diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID585865 | Antimicrobial activity against Pseudomonas aeruginosa isolate 13 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID572798 | Antimicrobial activity against marR-deficient Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID565035 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID556692 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes ATCC 15038 harboring pACM204 plasmid by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID559341 | Antimicrobial activity against Shigella flexneri harboring tetB gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID556686 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 13 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID556863 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 3 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID532982 | Antibacterial activity against Escherichia coli W3110 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID495513 | Antibacterial activity against Acinetobacter baumannii BM4467 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID556864 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 4 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1428346 | Antibacterial activity against Enterococcus faecalis CIP 103014 after 24 hrs | 2016 | Journal of natural products, Dec-23, Volume: 79, Issue:12 | Antimicrobial Oligophenalenone Dimers from the Soil Fungus Talaromyces stipitatus. |
| AID380475 | Antimicrobial activity against TetK multidrug efflux pump possessing Staphylococcus aureus XU-212 by standard microdilution method | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 | Polyacylated oligosaccharides from medicinal Mexican morning glory species as antibacterials and inhibitors of multidrug resistance in Staphylococcus aureus. |
| AID536631 | Antimicrobial activity against Escherichia coli NCTC 10416 at 5 mg/ml after 24 hrs by agar well diffusion assay | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents. |
| AID572801 | Antimicrobial activity against soxS::kan-deficient Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID588211 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID1688642 | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as diameter of inhibition zone at 0.5 mg/ml incubated for 24 hrs by agar diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID275055 | Antibacterial activity against Escherichia coli pTMV19 | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25 | Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin. |
| AID530539 | Induction of PvraSr::lacZ gene expression in Staphylococcus aureus SH1000 at 2 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID1240024 | Antibacterial activity against Bacillus cereus MTCC 8372 after 24 hrs by microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID565009 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID625282 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID360853 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 30 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID447075 | Antibacterial activity against Micrococcus luteus La 2971 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID565039 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID646233 | Apparent volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv by LC/MS-MS analysis | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID1431165 | Antibacterial activity against oxacillin/tetracycline-resistant Staphylococcus aureus NRS-100 after 18 hrs by two fold serial dilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: modifications at C12 and C7. |
| AID1551780 | Antibacterial activity against Salmonella typhimurium assessed as zone of inhibition | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID693551 | Antibacterial activity against Staphylococcus aureus after 48 hrs by well diffusion assay | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Facile water promoted synthesis of 1,2,3-triazolyl dihydropyrimidine-2-thione hybrids - highly potent antibacterial agents. |
| AID206303 | In vitro antibacterial activity against Staphylococcus aureus UBMS 90-1 Tet M | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID283149 | Antimicrobial susceptibility of Staphylococcus lugdunensis isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID368423 | Antimicrobial activity against Escherichia coli KAM32 pSTVdeltaqepA containing disrupted qepA gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID1442635 | Antibacterial activity against gram-positive Staphylococcus aureus SA101 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID565310 | Antibacterial activity against Mycoplasma genitalium G37 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID1482267 | Antibacterial activity against Escherichia coli MG1655 measured every 15 mins for 12 hrs | 2017 | Journal of medicinal chemistry, 05-11, Volume: 60, Issue:9 | Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure. |
| AID489649 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID388085 | Antifungal activity at Fusarium oxysporum | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents. |
| AID1228682 | Antibacterial activity against tet(K) tetracycline-resistant Staphylococcus aureus 158 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID396276 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(B), tet(D) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID278246 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-4 acrAB::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID572058 | Ratio of MIC for Escherichia coli KAM32 harboring plasmid pUC18 to MIC for Escherichia coli KAM32 harboring recombinant plasmid pVBS1 encoding Acinetobacter baumannii abeS gene | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii. |
| AID1055417 | Antibacterial activity against multidrug-resistant Pseudomonas aeruginosa B 63230 assessed as growth inhibition by broth microdilution method | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Inducing secondary metabolite production by the endophytic fungus Fusarium tricinctum through coculture with Bacillus subtilis. |
| AID532675 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID278860 | Antiproliferative effect against HeLa cells after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID323005 | Antibacterial activity against drug-resistant Propionibacterium acnes P429:1 (BC) after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID348887 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID588219 | FDA HLAED, gamma-glutamyl transferase (GGT) increase | 2004 | Current drug discovery technologies, Dec, Volume: 1, Issue:4 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. |
| AID348885 | Antibacterial activity against Micrococcus luteus PTCC 1110 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID250264 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH17; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID565312 | Antibacterial activity against Mycoplasma genitalium R32 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID491946 | Antibacterial activity against Dermabacter hominis DSM 7083 after 48 hrs by microtiter plate assay | 2010 | Journal of natural products, Jul-23, Volume: 73, Issue:7 | Mayamycin, a cytotoxic polyketide from a Streptomyces strain isolated from the marine sponge Halichondria panicea. |
| AID1269980 | Antimicrobial activity against Staphylococcus aureus RN4220 after 24 hrs by double dilution method | 2015 | MedChemComm, May-01, Volume: 6, Issue:5 | Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity. |
| AID404936 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus sp. by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID544029 | Antimicrobial activity against Bacillus psychrodurans isolate C328 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID562791 | Antimicrobial activity against Chlamydia trachomatis F/70/rifR harboring rpoB gene | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID587832 | Antibacterial activity against tetracycline-resistant Staphylococcus aureus isolate 158 harboring tet(K) gene by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID250265 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH18; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID576110 | Antimicrobial activity against mecA-positive Staphylococcus sciuri assessed as resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. |
| AID1124947 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 assessed as growth inhibition after 16 to 20 hrs by microbroth dilution method | 2014 | Bioorganic & medicinal chemistry, Apr-01, Volume: 22, Issue:7 | Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines. |
| AID1231524 | Antibacterial activity against Staphylococcus aureus CECT 86 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter broth dilution method | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antibacterial activities of cadiolides A, B and C and analogues. |
| AID496397 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT2 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID283165 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2664 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID423153 | Antibacterial activity against Bifidobacterium thermophilum B0242 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Mosaic tetracycline resistance genes and their flanking regions in Bifidobacterium thermophilum and Lactobacillus johnsonii. |
| AID501854 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID1058230 | Antimycobacterial activity against Mycobacterium smegmatis | 2013 | Bioorganic & medicinal chemistry, Dec-15, Volume: 21, Issue:24 | Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis. |
| AID1131166 | Antibacterial activity against Escherichia coli MB2884 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID1730998 | Antibacterial activity against Staphylococcus aureus Newman assessed as inhibition of bacterial growth measured after 18 hrs by two fold serial dilution method | 2021 | European journal of medicinal chemistry, Mar-05, Volume: 213 | Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules. |
| AID528725 | Antibacterial activity against Streptococcus intermedius clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID520963 | Antimicrobial activity against Arcanobacterium haemolyticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID404902 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID520964 | Antimicrobial activity against Rhodococcus equi isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID396271 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(A), tet(B) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID1131170 | Antibacterial activity against Streptococcus pyogenes assessed as growth inhibition at 2 to 8 ug/mL | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID404952 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus sp. assessed as percent susceptible isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID646216 | Antibacterial activity against Pseudomonas aeruginosa ATCC 111 27853 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID556873 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 13 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID30706 | Evaluated for the in vitro minimum bactericidal concentration (MBC) against periopathogenic Actinomycetes viscosus bacteria | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1 | Substituted 2-(2-hydroxyphenyl)benzimidazoles as potential agents for the control of periodontal diseases. |
| AID556899 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 11 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565444 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.05 ug/ml (Rvb =310.8 +/- 17.10 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID528731 | Antibacterial activity against penicillin intermediate Streptococcus pneumoniae clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID1442634 | Antibacterial activity against gram-negative Enterobacter cloacae EC1603 harboring tet(A) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID544021 | Antimicrobial activity against Psychrobacter sp. DY9-2 isolate C711 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID373747 | Antimicrobial activity against mupirocin-susceptible methicillin-resistant Staphylococcus aureus by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. |
| AID562784 | Antimicrobial activity against Chlamydia trachomatis J/6276/rifR harboring ompA and rpoB genes | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID283162 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2622 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID1269979 | Antimicrobial activity against Bacillus subtilis 168 after 24 hrs by double dilution method | 2015 | MedChemComm, May-01, Volume: 6, Issue:5 | Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity. |
| AID425603 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM580 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 10% compound Cmax a | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1335600 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID1514476 | Antibacterial activity against Bacillus subtilis after 24 hrs | 2018 | Bioorganic & medicinal chemistry, 12-15, Volume: 26, Issue:23-24 | Isolation and structure determination of a new lasso peptide specialicin based on genome mining. |
| AID1551808 | Antibacterial activity against Escherichia coli incubated for 18 hrs post 30 mins pre-diffusion by disk diffusion method | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID594331 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID749312 | Bactericidal activity against Bacillus cereus CECT 148 at 0.2 mg/disk after 24 hrs by paper disk-agar diffusion method | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11 | Novel isoquinoline derivatives as antimicrobial agents. |
| AID323036 | Antibacterial activity against Streptococcus pyogenes after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID565192 | Antimicrobial activity against Acinetobacter baumannii JVAB01 expressing disrupted open reading frame orf3 mutant deficient in efflux pump CraA by Etest | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii. |
| AID565637 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.08 ug/ml (Rvb =757.5 +/- 80.14 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID524650 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ mutant gene assessed as incidence of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID565019 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID295111 | Antibacterial activity against Bacillus cereus ATCC 7064 at 30 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID564807 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID70762 | In vitro minimum inhibitory concentration against Escherichia coli J3272 (tet D efflux). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID308344 | Antibacterial activity against Escherichia coli MTCCB 1610 | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID575055 | Antibacterial activity against Vibrio cholerae O1 CIP0.25-1 harboring Ser to Ile mutation at 83 position in gyrA and parC genes by 2-fold agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Reduced expression of the vca0421 gene of Vibrio cholerae O1 results in innate resistance to ciprofloxacin. |
| AID562790 | Antimicrobial activity against Chlamydia trachomatis J/6276/tetR harboring tet(C) allele | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID534341 | Antimicrobial activity against Burkholderia pseudomallei Bp227 harboring deleted (bpeAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID625280 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID369663 | Antibacterial activity against wild type Escherichia coli DH5alpha by agar dilution assay | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID283646 | Susceptibility of Escherichia coli K12 MG1655 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID545053 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ372 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID1681014 | Antibacterial activity against Salmonella typhi assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID556681 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 8 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID564829 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID425400 | Antibacterial activity against Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID532221 | Antibacterial activity against macrolide-lincosamide-streptogramin B-positive, beta-lactamase-positive, methicillin-resistant Staphylococcus aureus isolate 6 | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Combined antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone-spermine conjugate. |
| AID1079946 | Presence of at least one case with successful reintroduction. [column 'REINT' in source] | |||
| AID278866 | Decrease in lactate production in MG63 cells at 400 ug/ml by ELISA | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID369227 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID404903 | Antibacterial activity against Streptococcus bovis ATCC 33317 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID693552 | Antibacterial activity against Streptococcus pneumoniae after 48 hrs by well diffusion assay | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Facile water promoted synthesis of 1,2,3-triazolyl dihydropyrimidine-2-thione hybrids - highly potent antibacterial agents. |
| AID396268 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(D) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID561637 | Antibacterial activity against Helicobacter pylori ARHp80 by CLSI M100-S13 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Pyrazolopyrimidinediones are selective agents for Helicobacter pylori that suppress growth through inhibition of glutamate racemase (MurI). |
| AID564828 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus simulans after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID428428 | Antibacterial activity against Staphylococcus aureus after 24 hrs by well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of novel carbazole based macrocyclic amides as potential antimicrobial agents. |
| AID285850 | Antimicrobial activity against erythromycin-resistant Streptococcus pyogenes D-112 transconjugated with erm(B) and tet(M) genes | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID495515 | Antibacterial activity against Acinetobacter baumannii CIP70-10 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID70921 | In vitro antibacterial activity against Escherichia coli J3272 Tet C | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID649516 | Antimicrobial activity against Staphylococcus aureus SA 1199B over-expressing NorA MDR efflux pump after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry, Mar-15, Volume: 20, Issue:6 | Efficient synthesis and biological evaluation of proximicins A, B and C. |
| AID1079931 | Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] | |||
| AID565815 | Antimicrobial activity against Neisseria gonorrhoeae assessed as resistant isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Update on fusidic acid (CEM-102) tested against Neisseria gonorrhoeae and Chlamydia trachomatis. |
| AID239884 | pKa value of the compound | 2004 | Journal of medicinal chemistry, Jul-29, Volume: 47, Issue:16 | Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction. |
| AID544018 | Antimicrobial activity against Aerococcus viridans isolate PGS21 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID564810 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID285848 | Antimicrobial activity against erythromycin-resistant Streptococcus pyogenes C-105 transconjugated with erm(B) and tet(M) genes | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID564816 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1240031 | Antibacterial activity against Klebsiella pneumoniae MTCC 3384 assessed as concentration required to completely destroy test microorganisms after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID540930 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor 92G harboring rpsL gene with inserted glycine at position 92 after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID562474 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 transconjugant expressing beta-lactamase SHV-12 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID1055420 | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 assessed as growth inhibition by broth microdilution method | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Inducing secondary metabolite production by the endophytic fungus Fusarium tricinctum through coculture with Bacillus subtilis. |
| AID574546 | Antimicrobial activity against community-associated methicillin-resistant Staphylococcus aureus Sanger 252 | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID522668 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis B126 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID444053 | Renal clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID425393 | Antibacterial activity against mucosa-associated Escherichia coli isolates isolated from patients with Crohn's disease by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID250284 | Susceptibility testing against Pseudomonas aeruginosa ATCC 27853; S=Susceptible | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID556684 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 11 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1112104 | Antifungal activity against Microbotryum violaceum by agar diffusion test | 2012 | Fitoterapia, Apr, Volume: 83, Issue:3 | Pyrenocines J-M: four new pyrenocines from the endophytic fungus, Phomopsis sp. |
| AID489650 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID448510 | Antimicrobial activity against Staphylococcus aureus MTCCB 737 at 30 ug/mL after 16 to 20 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents. |
| AID1127616 | Antibacterial activity against fluoroquinolone-resistant Streptococcus pneumoniae D39 NCTC 7466 expressing ParE/GyrB T172A mutant assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID694205 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus 8325-4 by CLSI broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 22, Issue:22 | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. |
| AID565328 | Antibacterial activity against Mycoplasma genitalium M6282 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID556661 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 16 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID501849 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID671559 | Oral bioavailability in CD1 mouse at 30 mg/kg | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID396501 | Antibacterial activity against tetracycline-resistant Escherichia coli with single drug resistance determinant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID1551781 | Antibacterial activity against Shigella dysenteriae assessed as zone of inhibition | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID323907 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC G152D mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID449362 | Antimicrobial activity against Staphylococcus aureus MTCCB 737 at 30 ug/mL after 16 to 20 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety. |
| AID338053 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 16 hrs by microdilution assay | |||
| AID521803 | Antimicrobial activity against Francisella tularensis subsp. holarctica after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | In vitro susceptibility of isolates of Francisella tularensis types A and B from North America. |
| AID378117 | Antimicrobial activity against Bacillus cereus at 30 ug/disk by disk diffusion assay | 2005 | Journal of natural products, Jan, Volume: 68, Issue:1 | Cicadapeptins I and II: new Aib-containing peptides from the entomopathogenic fungus Cordyceps heteropoda. |
| AID585842 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1278315 | Antibacterial activity against Escherichia coli BL21 by microbroth dilution assay | 2016 | European journal of medicinal chemistry, Mar-03, Volume: 110 | Design, synthesis and biological evaluation of monobactams as antibacterial agents against gram-negative bacteria. |
| AID528710 | Antibacterial activity against penicillin intermediate Streptococcus pneumoniae clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID556889 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 1 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID561110 | Antibacterial activity against Pasteurella multocida BB1044 harboring plasmid pB1000 bearing blaROB-1 gene, plasmid 1006 bearing tetO gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID320390 | Antimicrobial activity against Staphylococcus aureus NCIM2122 by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of beta-lactam-bile acid conjugates linked via triazole. |
| AID477411 | Antibacterial activity against MBX-1090-resistant Staphylococcus aureus isolate d20A1 after 16 to 20 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID405080 | Antimicrobial activity against Citrobacter freundii 33587 isolate by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID509868 | Antibacterial activity against Acinetobacter baumannii isolate 2898 isolated from human ankle | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID1634993 | Antimicrobial activity against Escherichia coli assessed as reduction in bacterial growth after 20 hrs by drop diffusion test | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID531332 | Antibacterial activity against Pseudomonas aeruginosa PAO4290 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID1158054 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 after 16 hrs by serial dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla. |
| AID576741 | Antimicrobial activity against Bacillus anthracis by Etest | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Oligochlorophens are potent inhibitors of Bacillus anthracis. |
| AID323033 | Antibacterial activity against borderline oxacillin-resistant Staphylococcus aureus after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID353044 | Antimicrobial activity against Proteus mirabilis at 25 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID1182957 | Antibacterial activity against Pseudomonas aeruginosa B 63230 by broth microdilution method | 2014 | Journal of natural products, Jul-25, Volume: 77, Issue:7 | Trimeric anthracenes from the endophytic fungus Stemphylium globuliferum. |
| AID396266 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(B) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID572147 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBADomeganorM plasmid containing Neisseria gonorrhoeae multidrug efflux pump NorM after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID1304851 | Ratio of MIC for methicillin-resistant Staphylococcus aureus clinical isolate 2 in absence and presence of Cu2+ | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID544015 | Antimicrobial activity against Psychrobacter ikaite isolate C410 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID524662 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing penA mutant gene assessed as percentage intermediate isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID341058 | Activity of tetracycline efflux transporter TetA(B) in Escherichia coli DH5alpha membrane vesicles assessed as [3H]tetracycline uptake per mg of protein | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate. |
| AID340860 | Antimicrobial activity against vancomycin-intermediate resistant Staphylococcus aureus Mu50 vraG mutant microdilution assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus. |
| AID476288 | Antibacterial activity against Staphylococcus aureus MTCC 96 after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Poly(ethylene glycol) (PEG-400) as an alternative reaction solvent for the synthesis of some new 1-(4-(4'-chlorophenyl)-2-thiazolyl)-3-aryl-5-(2-butyl-4-chloro-1H-imidazol-5yl)-2-pyrazolines and their in vitro antimicrobial evaluation. |
| AID565291 | Antimicrobial activity against Mycoplasma hominis by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | In vitro activity of a new quinoline derivative, ER-2, against clinical isolates of Mycoplasma pneumoniae and Mycoplasma hominis. |
| AID667268 | Antibacterial activity against Pseudomonas aeruginosa at 1000 ug/ml after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. |
| AID406621 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Prevalence, characteristics, and molecular epidemiology of macrolide and fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae at five tertiary-care hospitals in Korea. |
| AID534343 | Antimicrobial activity against Burkholderia pseudomallei Bp173 harboring mini-Tn7T after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID1688656 | Bactericidal activity against Escherichia coli ATCC 25922 incubated for 24 hrs followed by transferring to freshly prepared broth medium and measured after 24 hrs by broth microdilution assay | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID278241 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-3 gyrA+ with ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID560247 | Antibacterial activity against Staphylococcus aureus RN4220 by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID250272 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH25; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID556655 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 10 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID559325 | Antimicrobial activity against Shigella flexneri assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID1325499 | Antibacterial activity against linezolid-resistant Staphylococcus aureus NRS-271 | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: Modifications at C-12. |
| AID1820915 | Antibacterial activity against Pseudomonas aeruginosa assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID522641 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis Ames by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID556879 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 19 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565015 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus simulans after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID523001 | Cytotoxicity against human 5637 cells assessed as mild induction of cell death by trypan blue exclusion assay | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID1681021 | Antibacterial activity against Staphylococcus aureus ATCC 6538 by CLSI method | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID1781498 | Anti-MDR bacterial activity against Salmonella typhimurium CCARM 8250 assessed as inhibition of bacterial growth incubated for 18 hrs by microplate reader analysis | |||
| AID278867 | Decrease in lactate production in HeLa cells at 400 ug/ml by ELISA | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID564813 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1061190 | Antimicrobial activity against Escherichia coli MTCC 724 at 50 ug/ml after 24 hrs by disc diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID548526 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1159087 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 35032 assessed as zone of inhibition at 30 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID548255 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID554873 | Antimicrobial activity against Streptococcus pneumoniae serotype 14 ST 13 harboring ERY-resistant mef(E) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID1360040 | Antimicrobial activity against Escherichia coli after 18 to 20 hrs by micro broth dilution method | 2018 | European journal of medicinal chemistry, Jun-25, Volume: 154 | Free radical rearrangement synthesis and microbiological evaluation of novel 2-sulfoether-4-quinolone scaffolds as potential antibacterial agents. |
| AID557083 | Antimicrobial activity against multidrug resistant Escherichia coli ATCC 35218 harboring pDrive plasmid by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID694394 | Bactericidal activity against Salmonella typhi CECT 409 at 0.2 mg/disk after 24 hrs by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones. |
| AID1250088 | Antibacterial activity against mexABCDXY-deficient Pseudomonas aeruginosa PAO1 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID560553 | Antimicrobial activity against Helicobacter pylori clinical isolate by Etest | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Antimicrobial susceptibility and mutations involved in clarithromycin resistance in Helicobacter pylori isolates from patients in the western central region of Colombia. |
| AID585854 | Antimicrobial activity against Pseudomonas aeruginosa isolate 7 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID594340 | Antimicrobial activity against Proteus vulgaris NCIM 2027/ATCC 13315 at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID718413 | Antibacterial activity against log-phase vancomycin-resistant Enterococcus faecalis ATCC 51575 assessed as growth inhibition after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. |
| AID278249 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS1 gyrA+ with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID544008 | Antimicrobial activity against Acinetobacter lwoffii isolate C2 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID532029 | Antimicrobial activity against Escherichia coli TOP10F' transformant harboring beta-lactamase CTX-M-78 by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID565433 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 biofilm assessed as biofilm bacterial count at 0.10 ug/ml (Rvb =402.9 +/- 26.88 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID323002 | Antibacterial activity against drug-resistant Propionibacterium acnes P401:5 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID528726 | Antibacterial activity against Streptococcus mitis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID320389 | Antimicrobial activity against Escherichia coli NCIM2574 by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of beta-lactam-bile acid conjugates linked via triazole. |
| AID588220 | Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset | 2008 | Toxicology mechanisms and methods, , Volume: 18, Issue:2-3 | Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. |
| AID1726826 | Antibacterial activity against methicillin resistant Staphylococcus aureus incubated for 14 to 16 hrs by micro broth dilution method | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6 | Sulfonium-based liposome-encapsulated antibiotics deliver a synergistic antibacterial activity. |
| AID585861 | Antimicrobial activity against Pseudomonas aeruginosa isolate 11 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID563501 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens 01 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID1243995 | Antimicrobial activity against Escherichia coli by agar dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents. |
| AID299672 | Antibacterial activity against methicillin-resistant Staphylococcus aureus CMAH 0430 by disk diffusion method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID449360 | Antimicrobial activity against Escherichia coli MTCCB 1652 after 24 hrs by tube dilution technique | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety. |
| AID588215 | FDA HLAED, alkaline phosphatase increase | 2004 | Current drug discovery technologies, Dec, Volume: 1, Issue:4 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. |
| AID644026 | Antimicrobial activity against Klebsiella pneumoniae at 25 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID534827 | Antimicrobial activity against Campylobacter fetus subsp. fetus CA75 harboring pCA75 carrying ant(6)-Ib resistant gene of 1516477 in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID556876 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 16 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID556882 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 22 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1585463 | Antibacterial activity against gentamicin-resistant Staphylococcus aureus NRS-108 measured after 16 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents. |
| AID725541 | Potentiation of tetracycline antimicrobial activity against methicillin-resistant Staphylococcus aureus at 10 ug/ml after 20 hrs by liquid microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3 | Discovery of nosokophic acid, a predicted intermediate of moenomycins, from nosokomycin-producing Streptomyces sp. K04-0144. |
| AID425610 | Cytotoxicity against mouse J774A1 cells assessed as macrophage number at 1.7 ug/ml after 3 hrs by total cell protein assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID369660 | Antibacterial activity against Campylobacter jejuni 81-176 carrying tet(O)+ gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID587835 | Antibacterial activity against Escherichia coli ATCC 25922 by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID524653 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ, penB and mtrR mutant gene assessed as incidence of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID428290 | Antimicrobial activity against Acinetobacter baumannii BM4454 isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID547528 | Antimicrobial activity against Streptococcus intermedius obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of 5% defr | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID572593 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium 902SA92 harboring GyrA S83A and D87N, GyrB S464F and ParC S80I mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID278673 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 5734 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID559328 | Antimicrobial activity against Salmonella enterica serovar Typhimurium assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID559344 | Antimicrobial activity against Shigella sonnei harboring tetB gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID287374 | Antibacterial activity against Bacillus cereus after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID278666 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5739 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID529899 | Antimicrobial activity against Leptospira weilii isolate 8 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID528730 | Antibacterial activity against penicillin resistant Streptococcus pneumoniae clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID307121 | Inhibition of HIV1 recombinant integrase 3'-processing activity | 2007 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 17, Issue:8 | Newer tetracycline derivatives: synthesis, anti-HIV, antimycobacterial activities and inhibition of HIV-1 integrase. |
| AID554657 | Antimicrobial activity against Ureaplasma parvum SV1 isolate UHWO10 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID625287 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID556885 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 25 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1228686 | Antibacterial activity against Escherichia coli 107 ATCC 25922 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID561341 | Antibacterial activity against Methicillin-resistant Staphylococcus aureus by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID1348088 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 assessed as zone of inhibition at 50 ug per disc after 24 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID532580 | Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing ramA::aph mutant by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. |
| AID278251 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS1 tolC::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID325444 | Antibacterial activity against Escherichia coli K12 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID542420 | Antimicrobial activity against Acinetobacter sp. N2 isolate C439 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1634989 | Antimicrobial activity against Staphylococcus aureus 6271 assessed as reduction in bacterial growth after 20 hrs by drop diffusion test | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID467965 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 9027 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID671551 | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 isolate 106 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID368419 | Antimicrobial activity against Escherichia coli KAM32 expressing deltaacrB ydhE hsd gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID285197 | Antimicrobial activity against Escherichia coli M083 mutant with AG100 lon4::IS186 acrR::IS1 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID1698039 | Antibacterial activity against Enterobacter aerogenes assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID557793 | Antimicrobial activity against Streptococcus pyogenes clinical isolate expressing mef(A) gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Characterization of macrolide efflux pump mef subclasses detected in clinical isolates of Streptococcus pyogenes isolated between 1999 and 2005. |
| AID565040 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID569307 | Antibacterial activity against Salmonella typhi at 100 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID529301 | Antimicrobial activity against Enterococcus faecalis expressing rRNA methylase gene erm(A) obtained from pig manure by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Detection of the erythromycin rRNA methylase gene erm(A) in Enterococcus faecalis. |
| AID532766 | Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing ramA::aph-pTRC hisA:ramA mutant by broth dilution method in presence of chlorpromzine | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. |
| AID1338315 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 20 hrs by microbroth dilution method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | New family of antimicrobial agents derived from 1,4-naphthoquinone. |
| AID325004 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 115 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID501855 | Antibacterial activity against Bacillus cereus food isolate after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID1376894 | Antimicrobial activity against Pseudomonas aeruginosa DSM 50071 assessed as growth inhibition at 7 ug per disc after 24 to 48 hrs (Rvb = 0 millimeter) | |||
| AID520399 | Antibacterial activity against mef and erm(B) positive Streptococcus pneumoniae isolates assessed as resistance incidence by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID565008 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID554654 | Antimicrobial activity against Ureaplasma parvum SV6 isolate HPA23 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID556892 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 4 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565230 | Antimicrobial activity against Mycobacterium chelonae 9917 by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID646217 | Antibacterial activity against Enterobacter cloacae ATCC 108 13047 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID501852 | Antibacterial activity against Proteus vulgaris ATCC 8427 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID1571236 | Inhibition of planktonic growth of Streptococcus gordonii at 40 uM by standard optical density assay relative to control | |||
| AID646355 | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg by LC/MS-MS analysis | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID572787 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium 543SA98 harboring GyrA S83F mutant gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID534339 | Antimicrobial activity against Burkholderia pseudomallei 1026b after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID70765 | In vitro minimum inhibitory concentration against Escherichia coli UBMS 90-4 (tet M ribosomal protection). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID278262 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS14 acrAB::Kan with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1617788 | Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 24 hrs by broth microdilution method | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12 | Structural Characterization and Anti-infective Activity of 9,10-Seco-29-norcycloartane Glycosides Isolated from the Flowers of the Peruvian Medicinal Plant |
| AID539666 | Antimicrobial activity against Bacillus subtilis by well diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno[3,4-b]pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens. |
| AID283559 | Antibacterial activity against Escherichia coli AG102MB after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. |
| AID1688644 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as diameter of inhibition zone at 0.5 mg/ml incubated for 24 hrs by agar diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID658546 | Antimycobacterial activity against Salmonella enterica serovar Typhimurium L10 after 24 hrs | 2012 | Journal of natural products, Mar-23, Volume: 75, Issue:3 | Antibacterial acylphloroglucinols from Hypericum olympicum. |
| AID477098 | Antimicrobial activity against Proteus vulgaris MTCC 1771 at 10 ug/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID572806 | Antimicrobial activity against Salmonella enterica serovar Typhimurium BN18 harboring plasmid encoded RamR gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID564821 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID278668 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 2530 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID1335594 | Antibacterial activity against methicillin resistant Staphylococcus aureus MFBF 10679 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID1191416 | Antimicrobial activity against Pseudomonas aeruginosa PCM 2562 (ATCC9027) after 16 to 20 hrs by broth micro-dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 25, Issue:3 | In vitro studies of antimicrobial activity of Gly-His-Lys conjugates as potential and promising candidates for therapeutics in skin and tissue infections. |
| AID404934 | Antibacterial activity against methicillin-resistant Staphylococcus aureus by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID334153 | Antimicrobial activity against Staphylococcus aureus at 30 ug by antimicrobial disk assay | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | New phomopsolides from a Penicillium sp. |
| AID1392013 | Antistaphylococcal activity against gentamicin-resistant Staphylococcus aureus NRS-108 after 18 hrs by two-fold serial dilution method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10 | The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid. |
| AID565813 | Antimicrobial activity against Neisseria gonorrhoeae assessed as susceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Update on fusidic acid (CEM-102) tested against Neisseria gonorrhoeae and Chlamydia trachomatis. |
| AID562475 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID749310 | Bactericidal activity against Enterococcus faecalis CECT 481 at 0.2 mg/disk after 24 hrs by paper disk-agar diffusion method | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11 | Novel isoquinoline derivatives as antimicrobial agents. |
| AID587844 | Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 10 mg/kg, po | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID489653 | Antibacterial activity against Bacillus cereus ATCC 13061 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID324196 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 at 12.5 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID353050 | Antimicrobial activity against Staphylococcus aureus at 75 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID1577570 | Antibacterial activity against Bacillus subtilis assessed as inhibition of bacterial growth after 24 hrs by microdilution method | |||
| AID278258 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS9 acrAB::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID717272 | Antimicrobial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 by CLSI protocol based broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. |
| AID1820914 | Antibacterial activity against Escherichia coli assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID565635 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 planktonic cells assessed as bacterial count at 0.10 ug/ml (Rvb =791.7 +/- 44.10 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID278859 | Inhibition of metabolic activity in MG63 cells assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID56758 | Inhibition zone when tested against DAP-AT from Escherichia coli in L-agar at concentration 0.3 ug | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8 | Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. |
| AID592502 | Antibacterial activity against Legionella pneumophila Corby by microtiter plate assay | 2011 | Journal of natural products, Mar-25, Volume: 74, Issue:3 | Diversonol and blennolide derivatives from the endophytic fungus Microdiplodia sp.: absolute configuration of diversonol. |
| AID341948 | Antimicrobial activity against Pseudomonas aeruginosa | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15 | Synthesis of some novel imidazole-based dicationic carbazolophanes as potential antibacterials. |
| AID554655 | Antimicrobial activity against Ureaplasma parvum SV14 isolate HPA32 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID524675 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ and penB mutant gene assessed as percentage intermediate isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID1338319 | Antibacterial activity against Escherichia coli ATCC 8739 after 20 hrs by microbroth dilution method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | New family of antimicrobial agents derived from 1,4-naphthoquinone. |
| AID545045 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ082 from patient bile by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID340859 | Antimicrobial activity against vancomycin-intermediate resistant Staphylococcus aureus Mu50 graR mutant microdilution assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus. |
| AID624612 | Specific activity of expressed human recombinant UGT1A9 | 2000 | Annual review of pharmacology and toxicology, , Volume: 40 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. |
| AID293953 | Inhibition of human MMP3 | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6 | Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases. |
| AID644023 | Antimicrobial activity against Pseudomonas aeruginosa at 50 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID565034 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID522111 | Antimicrobial activity against Escherichia coli isolates producing extended-spectrum beta-lactamases bla(CTX-M-1), bla(CTX-M-32) and bla(SHV-12) assessed as resistant isolates isolated from Italian broiler flocks by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | High diversity of extended-spectrum beta-lactamases in Escherichia coli isolates from Italian broiler flocks. |
| AID572802 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S/921495 harboring plasmid encoded RamR gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1551806 | Antibacterial activity against Micrococcus luteus incubated for 18 hrs post 30 mins pre-diffusion by disk diffusion method | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID477105 | Antimicrobial activity against Aspergillus niger MTCC 1781 at 30 ug/ml after 48 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID585860 | Antimicrobial activity against Pseudomonas aeruginosa isolate 10 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID324199 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid vector at 12.5 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID388084 | Antifungal activity at Yarrowia lipolytica | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents. |
| AID70931 | In vitro antibacterial activity against Escherichia coli UBMS 90-5 sensitive | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID594339 | Antimicrobial activity against Proteus vulgaris NCIM 2027/ATCC 13315 at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID601194 | Apparent volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv administered as single dose measured after 24 to 48 hrs | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID428272 | Antimicrobial activity against carbapenemase producing Enterobacter sp. by CLSI broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID278667 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 2513 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID565004 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID341057 | Antibacterial activity against intact Escherichia coli DH5alpha | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate. |
| AID325016 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 833 isolate with erm(B) resistance gene from patient sinuitis by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID1442637 | Antibacterial activity against gram-positive Staphylococcus aureus SA158 harboring tet(K) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID535639 | Antimicrobial activity against Group B streptococcus serotype VI R1 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1726841 | Synergistic antibacterial activity against Escherichia coli assessed as tetracyclin MIC encapsulated by compound | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6 | Sulfonium-based liposome-encapsulated antibiotics deliver a synergistic antibacterial activity. |
| AID206121 | In vitro minimum inhibitory concentration against Staphylococcus aureus UBMS 90-3 (sensitive). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID428271 | Antimicrobial activity against Klebsiella sp. assessed as resistant isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID565016 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1725194 | Antibacterial activity against Porphyromonas gingivalis 381 assessed as bacterial growth inhibition at 2.81 uM treated for 24 hrs by WST1 assay relative to control | |||
| AID325021 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 1017 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID530548 | Induction of PtcaA::lacZ gene expression in Staphylococcus aureus SH1000 at 2 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID533659 | Antimicrobial activity against Staphylococcus aureus RN4220 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID1347485 | Antibacterial activity against Klebsiella pneumoniae assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID564806 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID275056 | Antibacterial activity against Escherichia coli pTMV19 in presence of mevalonate | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25 | Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin. |
| AID283659 | Antimicrobial activity against Haemophilus influenzae CDS01 mutant with acrB insertional inactivation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number. |
| AID425407 | Antibacterial activity against mucosa-associated Escherichia coli isolate HM456 isolated from patient with irritable bowel syndrome or sporadic polyps after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID575948 | Antimicrobial activity against erythromycin-resistant Streptococcus pneumoniae assessed as resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates. |
| AID311291 | Antibacterial activity against Proteus vulgaris at pH 7 | 2007 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18 | Synthesis and antibacterial activity of some novel chiral fluorophoric biscyclic macrocycles. |
| AID372900 | Antibacterial activity against Enterobacter cloacae ATCC 13047 after 24 hrs by MTT assay | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. |
| AID544286 | Antimicrobial activity against Enterococcus faecalis NKH16 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID646205 | Inhibition of Escherichia coli ribosome-mediated translation after 60 mins by transcription/translation-coupled luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID250270 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH23; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID693553 | Antibacterial activity against Pseudomonas aeruginosa after 48 hrs by well diffusion assay | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Facile water promoted synthesis of 1,2,3-triazolyl dihydropyrimidine-2-thione hybrids - highly potent antibacterial agents. |
| AID417534 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by NLCCS microdilution method | 2009 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 19, Issue:5 | Synthesis and antibacterial activity evaluation of metronidazole-triazole conjugates. |
| AID625279 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID285198 | Antimicrobial activity against Escherichia coli M084 mutant AG100 lon4::IS186 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID311290 | Antibacterial activity against Escherichia coli at pH 7 | 2007 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18 | Synthesis and antibacterial activity of some novel chiral fluorophoric biscyclic macrocycles. |
| AID315456 | Toxicity in human erythrocytes assessed as hemolysis upto 62.5 ug/mL | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of 3-arylamino-1-chloropropan-2-ols. |
| AID588119 | Antimicrobial activity against Neisseria gonorrhoeae clinical isolates after 24 hrs by agar dilution method | 2011 | Antimicrobial agents and chemotherapy, Feb, Volume: 55, Issue:2 | Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. |
| AID565636 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 planktonic cells assessed as bacterial count at 0.12 ug/ml (Rvb =791.7 +/- 44.10 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1525329 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 2011 after 20 hrs by CLSI-based microdilution method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance. |
| AID557794 | Antimicrobial activity against Streptococcus pyogenes clinical isolate expressing mef(E) gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Characterization of macrolide efflux pump mef subclasses detected in clinical isolates of Streptococcus pyogenes isolated between 1999 and 2005. |
| AID544030 | Antimicrobial activity against Acinetobacter baumannii isolate C442 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID405925 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Inhibitors of bacterial multidrug efflux pumps from the resin glycosides of Ipomoea murucoides. |
| AID556870 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 10 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID278228 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21 | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID671550 | Antibacterial activity against tetracycline-resistant Staphylococcus aureus isolate SA158 expressing TetK gene | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID1678780 | Antibacterial activity against Enterococcus faecalis ATCC 51299 using Cyrene as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID341056 | Antibacterial activity against intact Escherichia coli DH5alpha expressing tetracycline efflux transporter TetA(B) Asp190Cys mutant gene | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate. |
| AID1781492 | Anti-MDR bacterial activity against Staphylococcus aureus CCARM 3090 assessed as inhibition of bacterial growth incubated for 18 hrs by microplate reader analysis | |||
| AID565622 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.15 ug/ml (Rvb =757.5 +/- 80.14 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID678444 | Antibacterial activity against Salmonella enterica at 12 ug/well after 24 hrs by agar well diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. |
| AID535632 | Antimicrobial activity against Group B streptococcus R8 harboring T77I, S353F and A514V in PBP 2X; V80A and G613R in PBP 2B; and L45P, N163K, N723S and G527V in PBP 1A by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID278681 | Antibacterial activity against Enterococcus faecium isolate 5752 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID323009 | Antibacterial activity against drug-resistant Propionibacterium acnes FG7E after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID556699 | Antimicrobial activity against multidrug resistant Escherichia coli ATCC 35218 harboring pDrive plasmid by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1158052 | Antimicrobial activity against Escherichia coli ATCC 25922 after 16 hrs by serial dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla. |
| AID1055422 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as growth inhibition by broth microdilution method | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Inducing secondary metabolite production by the endophytic fungus Fusarium tricinctum through coculture with Bacillus subtilis. |
| AID556883 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 23 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID576112 | Antimicrobial activity against mecA-positive Staphylococcus sciuri harboring staphylococcus aureus mecA gene assessed as resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. |
| AID569039 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs micro dilution assay | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis, antimicrobial activity and structure-activity relationship study of N,N-dibenzyl-cyclohexane-1,2-diamine derivatives. |
| AID1348089 | Antimicrobial activity against Bacillus subtilis subsp. subtilis ATCC 6051 assessed as zone of inhibition at 50 ug per disc after 24 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID1347491 | Antibacterial activity against Escherichia coli assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID565064 | Antibacterial activity against SHV-12 ESBL producing Enterobacter cloacae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID528919 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae expressing beta-lactamase CTX-M-14 and CTX-M-27 gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID285836 | Antimicrobial activity against tetracycline-susceptible Streptococcus pyogenes iMLS-A isolate expressing erm(B) | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID561340 | Antibacterial activity against Methicillin-sensitive Staphylococcus aureus by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID369657 | Antibacterial activity against Campylobacter jejuni 15-21 cmeB:: Kanamycin-resistant mutant by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID543352 | Antimicrobial activity against Salmonella serogroup O7 assessed as percent tetracyclin-resistant isolate at 1 to >128 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID585431 | Antimicrobial activity against oqxAB positive Escherichia coli C600 D83-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1634991 | Antimicrobial activity against Staphylococcus aureus clinical isolates from Liberec regional hospital assessed as reduction in bacterial growth after 20 hrs by drop diffusion test | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID556674 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 1 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID556904 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 16 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID323020 | Antibacterial activity against drug-resistant Propionibacterium acnes GE4E after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID369235 | Antibacterial activity against inducible macrolide-lincosamide-streptogramin B-resistant Streptococcus pneumoniae expressing erm(B) and tet(M) genes assessed as percent resistant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID585848 | Antimicrobial activity against Pseudomonas aeruginosa isolate 4 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID399616 | Antimicrobial activity against Klebsiella pneumoniae ATCC 13883 at 0.1 mg/disk by disk diffusion assay | |||
| AID67234 | In vitro minimum inhibitory concentration against Enterococcus faecalis ATCC 29212. | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID1250082 | Inhibition of transcription-translation process in Escherichia coli | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID585864 | Antimicrobial activity against Pseudomonas aeruginosa isolate 12 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID494535 | Antimicrobial activity against Salmonella typhi NCIM 2501 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494535 | Antimicrobial activity against Salmonella typhi NCIM 2501 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID569308 | Antibacterial activity against Staphylococcus aureus at 25 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID569309 | Antibacterial activity against Staphylococcus aureus at 50 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID362546 | Antibacterial activity against epidemic methicillin-resistant Staphylococcus aureus 16 after 18 hrs | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. |
| AID565613 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 planktonic cells assessed as bacterial count at 0.15 ug/ml (Rvb =791.7 +/- 44.10 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID283557 | Antimicrobial activity against Streptococcus pneumoniae R6 with L4 69GTG71 to TPS mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID87953 | Minimum inhibitory concentration against Helicobacter pylori (Helicobacter pylori) ARHp strain 81 | 2002 | Journal of medicinal chemistry, Sep-12, Volume: 45, Issue:19 | Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 2. |
| AID544012 | Antimicrobial activity against Arthrobacter arilaitensis isolate C361 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID287379 | Antibacterial activity against Pseudomonas aeruginosa after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID404953 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus sp. assessed as percent resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID543351 | Antimicrobial activity against Salmonella serotype Typhimurium assessed as percent tetracyclin-resistant isolate at 1 to >128 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID739298 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as growth inhibition by CLSI broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. |
| AID1348084 | Antimicrobial activity against Candida albicans ATCC 10231 assessed as zone of inhibition at 50 ug per disc after 48 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID572061 | Ratio of MIC for Acinetobacter baumannii AC0037 to MIC for abeS-deficient Acinetobacter baumannii AC0037 | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii. |
| AID396278 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(C), tet(E) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID642766 | Antimicrobial activity against Bacillus subtilis at 25 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID1240016 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 100 ug/ml after 24 hrs by disc diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID338054 | Antibacterial activity against Escherichia coli ATCC 25922 after 16 hrs by microdilution assay | |||
| AID1672291 | Antifungal activity against Candida tropicalis assessed as fungal growth inhibition after 24 hrs by CLSI protocol based broth microdilution assay | |||
| AID1237960 | Inhibition of beta-haematin formation by microplate reader analysis relative to hemin | 2015 | Bioorganic & medicinal chemistry, Aug-15, Volume: 23, Issue:16 | Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity. |
| AID230771 | Range for minimum inhibitory concentration against Staphylococcus aureus 0.5->16 | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6 | New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine. |
| AID534403 | Antibacterial activity against Escherichia coli EPI300 expressing tet(40) gene assessed as inhibition of bacterial growth at 60 ug/ml after 18 hrs in presence of 2.5 ug/ml efflux pump inhibitor CCCP | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones. |
| AID561738 | Antibacterial activity against Beta-hemolytic Streptococcus group A assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID1238342 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by agar diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 25, Issue:16 | Antibacterial activity of diketopiperazines isolated from a marine fungus using t-butoxycarbonyl group as a simple tool for purification. |
| AID565311 | Antibacterial activity against Mycoplasma genitalium M30 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID544284 | Antimicrobial activity against Enterococcus faecalis NKH14 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID534163 | Antimicrobial activity against Campylobacter coli assessed as resistant rate | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Comparison of disk diffusion and agar dilution methods for erythromycin, ciprofloxacin, and tetracycline susceptibility testing of Campylobacter coli and for tetracycline susceptibility testing of Campylobacter jejuni subsp. jejuni. |
| AID285841 | Antimicrobial activity against tetracycline-susceptible Streptococcus pyogenes cMLS isolate C expressing tet(M), Xis, tnpA, tnpR gene | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID521968 | Antibacterial activity against Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID565057 | Antibacterial activity against wild-type Escherichia coli AG100 harboring Tn5 insertion in ycgE gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID341946 | Antimicrobial activity against Proteus vulgaris | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15 | Synthesis of some novel imidazole-based dicationic carbazolophanes as potential antibacterials. |
| AID561105 | Antibacterial activity against Pasteurella multocida BB1039 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID380476 | Antimicrobial activity against NorA multidrug efflux pump overexpressing Staphylococcus aureus 1199B by ethidium efflux assay | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 | Polyacylated oligosaccharides from medicinal Mexican morning glory species as antibacterials and inhibitors of multidrug resistance in Staphylococcus aureus. |
| AID530769 | Antimicrobial activity against beta-lactamase producing Staphylococcus aureus SH1000 | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID644022 | Antimicrobial activity against Pseudomonas aeruginosa at 25 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID532989 | Antibacterial activity against Klebsiella aerogenes NCIM 2281 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1061176 | Antimicrobial activity against Escherichia coli MTCC 724 after 24 hrs by microdilution method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID278240 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-3 with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID396502 | Antibacterial activity against tetracycline-resistant Escherichia coli with multiple drug resistance determinant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID449363 | Antimicrobial activity against Staphylococcus epidermidis MTCCB 1824 at 30 ug/mL after 16 to 20 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety. |
| AID749309 | Bactericidal activity against Salmonella typhi CECT 409 at 0.2 mg/disk after 24 hrs by paper disk-agar diffusion method | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11 | Novel isoquinoline derivatives as antimicrobial agents. |
| AID532220 | Antibacterial activity against macrolide-lincosamide-streptogramin B-negative, beta-lactamase-positive, methicillin-susceptible Staphylococcus aureus isolate 5 | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Combined antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone-spermine conjugate. |
| AID1688648 | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as reduction in bacterial growth incubated for 1 day by paper disk diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID299674 | Antibacterial activity against methicillin-resistant Staphylococcus aureus CMAH 0515 by disk diffusion method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID1442640 | Antibacterial activity against gram-positive Streptococcus pneumoniae SP193 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID1678760 | Antibacterial activity against Klebsiella pneumoniae ATCC 700603 using DMSO as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID396277 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(B), tet(E) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID1228680 | Antibacterial activity against Staphylococcus aureus 101 ATCC 29213 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID417533 | Antibacterial activity against Escherichia coli after 24 hrs by NCCLS microdilution method | 2009 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 19, Issue:5 | Synthesis and antibacterial activity evaluation of metronidazole-triazole conjugates. |
| AID533664 | Antimicrobial activity against Staphylococcus aureus RN1024-tms | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID323017 | Antibacterial activity against drug-resistant Propionibacterium acnes SW3CD after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1617936 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as bacterial growth inhibition measured after 48 hrs by resazurin assay | |||
| AID563511 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens HMS011 harboring plasmid STV28 expressing sdeB gene by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID584821 | Effect on Pseudomonas putida PAW340 biofilms assessed as heat production at 3 ug/ml by Chip calorimetry | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Chip calorimetry for fast and reliable evaluation of bactericidal and bacteriostatic treatments of biofilms. |
| AID509631 | Antimicrobial activity against Staphylococcus aureus RN4220 transformant carrying plasmid pKKS25 and expressing erm(T), dfrK and tet(L) genes by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID341949 | Antimicrobial activity against Salmonella typhi | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15 | Synthesis of some novel imidazole-based dicationic carbazolophanes as potential antibacterials. |
| AID534829 | Antimicrobial activity against Campylobacter fetus subsp. fetus CA80 harboring ciprofloxacin-resistant gene and IMD523-06 pathogenicity island with tet(44) and ant(6)-Ib resistant marker gene in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID532024 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H carrying the luxAB gene under the hsp60 promoter determined after 14 days in presence of 2.5 ug/ml ATP-cassette transporter inhibitor reserpine | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID531625 | Antimicrobial activity against Mycoplasma pneumoniae by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. |
| AID456847 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by microdilution assay | 2010 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3 | Synthesis and antibacterial activity of benzyl-[3-(benzylamino-methyl)-cyclohexylmethyl]-amine derivatives. |
| AID531628 | Antimicrobial activity against Mycoplasma fermentans by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. |
| AID554674 | Antimicrobial activity against Streptococcus pneumoniae serotype 14 ST 156 harboring ERY-resistant mef(E) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID456846 | Antimicrobial activity against Escherichia coli after 24 hrs by microdilution assay | 2010 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3 | Synthesis and antibacterial activity of benzyl-[3-(benzylamino-methyl)-cyclohexylmethyl]-amine derivatives. |
| AID375938 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 after 24 hrs by broth microdilution method | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens. |
| AID565193 | Antimicrobial activity against efflux pump CraA deficient Acinetobacter baumannii JVAB01 receiving pJV103 harboring open reading frame orf3 encoded efflux pump CraA by Etest | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii. |
| AID522364 | Antimicrobial activity against PpmrI knockout mutant Proteus mirabilis dIp after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID531333 | Antibacterial activity against Pseudomonas aeruginosa PAO4290 selected after 1.0 ug/ml of azithromycin by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID395369 | Antibacterial activity against Klebsiella pneumoniae UC57 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID315449 | Antibacterial activity against Pseudomonas aeruginosa by microbroth dilution assay | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of 3-arylamino-1-chloropropan-2-ols. |
| AID1243992 | Antimicrobial activity against Staphylococcus citreus by agar dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents. |
| AID508593 | Antibacterial activity against ciprofloxacin-susceptibility revert strain of Salmonella enteritidis 104 harboring gyrA D87Y/S83F mutant, parC D79N mutant, soxR E16G/R20H mutant and soxS E52K mutant gene after 20 passages by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID428426 | Antibacterial activity against Proteus mirabilis after 24 hrs by well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of novel carbazole based macrocyclic amides as potential antimicrobial agents. |
| AID532988 | Antibacterial activity against Klebsiella aerogenes NCIM 2281 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID572795 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium BN9181 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID585418 | Antimicrobial activity against Escherichia coli C600 by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1304850 | Ratio of MIC for methicillin-resistant Staphylococcus aureus clinical isolate 2 in absence and presence of tiron | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID568332 | Antimicrobial activity against wild type Pseudomonas aeruginosa by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID406842 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolates | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Prospective randomized trial of empiric therapy with trimethoprim-sulfamethoxazole or doxycycline for outpatient skin and soft tissue infections in an area of high prevalence of methicillin-resistant Staphylococcus aureus. |
| AID325012 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 547 isolate with erm(B) resistance gene from patient sinuitis by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID520392 | Antibacterial activity against mef and erm(B) positive Streptococcus pneumoniae isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID558075 | Cytotoxicity against normal human epidermal keratinocytes at 100 uM after 72 hrs by MTT assay | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. |
| AID558082 | Cytotoxicity against normal human epidermal keratinocytes at 5 uM after 72 hrs by MTT assay | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. |
| AID1240029 | Antibacterial activity against Escherichia coli MTCC 724 assessed as concentration required to completely destroy test microorganisms after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID1131169 | Antibacterial activity against Bordetella bronchiseptica MB905 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID1879067 | Antibacterial activity against pET28a-NDM-1 positive Escherichia coli BL21(DE3) isolates assessed as inhibition of bacterial growth incubated for 18 to 24 hrs by CLSI based broth microdilution method | 2022 | European journal of medicinal chemistry, Mar-05, Volume: 231 | Metallo-β-lactamases inhibitor fisetin attenuates meropenem resistance in NDM-1-producing Escherichia coli. |
| AID520962 | Antimicrobial activity against Corynebacterium xerosis isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID297186 | Antibacterial activity against multidrug resistant Staphylococcus aureus 49589 | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17 | Structure-activity relationships of phenyl-furanyl-rhodanines as inhibitors of RNA polymerase with antibacterial activity on biofilms. |
| AID556697 | Antimicrobial activity against multidrug resistant Escherichia coli DH5[alpha] harboring pACM204 plasmid by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1127622 | Antibacterial activity against fluoroquinolone-resistant Streptococcus pneumoniae D39 NCTC 7466 expressing GyrA S81Y/ParC S79F double mutant assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID529302 | Antimicrobial activity against Enterococcus faecalis expressing rRNA methylase gene erm(A) obtained from human by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Detection of the erythromycin rRNA methylase gene erm(A) in Enterococcus faecalis. |
| AID585843 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID285524 | Antibacterial activity against Neisseria gonorrhoeae after 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID498360 | Antimicrobial activity against rifampin resistant Klebsiella pneumoniae 52145R assessed as growth inhibition by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. |
| AID1079945 | Animal toxicity known. [column 'TOXIC' in source] | |||
| AID625291 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID325984 | Antimicrobial activity against Streptococcus pneumoniae spain 23F-1 | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci. |
| AID528727 | Antibacterial activity against Streptococcus agalactiae group B clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID678713 | Inhibition of human CYP2C9 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 7-methoxy-4-trifluoromethylcoumarin-3-acetic acid as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID1240019 | Antibacterial activity against Klebsiella pneumoniae MTCC 3384 at 50 ug/ml after 24 hrs by disc diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID360380 | Antimalarial activity after 96 hrs against azithromycin-resistant Plasmodium falciparum Dd2 by [3H]hypoxanthine uptake | 2007 | The Journal of biological chemistry, Jan-26, Volume: 282, Issue:4 | In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. |
| AID574169 | Antibacterial activity against Escherichia coli MG1655 harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes grown as planktonic cells after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID520956 | Antimicrobial activity against Corynebacterium amycolatum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID495509 | Antibacterial activity against Acinetobacter baumannii BM4587 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID563509 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 79 harboring plasmid STV29 expressing hasF gene by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID396500 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates without tet(B) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID520396 | Antibacterial activity against mef(E) and mef(A)-positive Streptococcus pneumoniae isolate CC-6B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID554869 | Antimicrobial activity against Streptococcus pneumoniae serotype 23F ST 961 harboring ERY-resistant erm(B) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID279193 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus isolates from skin or soft tissue infection outpatients | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Treatment and outcomes of infections by methicillin-resistant Staphylococcus aureus at an ambulatory clinic. |
| AID396265 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(A) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID625283 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID324193 | Antibacterial activity against Escherichia coli K12 mutant JHU313 at 50 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID287378 | Antibacterial activity against Listeria monocytogenes after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID283160 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2554 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID522657 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis V770 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID1442641 | Antibacterial activity against gram-negative Escherichia coli EC107 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID324169 | Antibacterial activity against Escherichia coli K12 mutant JHU313 at 25 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID425405 | Antibacterial activity against mucosa-associated Escherichia coli isolate HM428 isolated from patient with irritable bowel syndrome or sporadic polyps after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID560774 | Antibacterial activity against Staphylococcus aureus TS5337 harboring ddlA Pro178Ser mutation after 20 hrs | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID1348082 | Antimicrobial activity against Candida tropicalis ATCC 13803 assessed as zone of inhibition at 50 ug per disc after 48 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID522654 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis K4539 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID546621 | Antimicrobial activity against Escherichia coli harboring plasmid pPCRScript by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID325022 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 1022 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID283167 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL5254 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID396026 | Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID1678769 | Antibacterial activity against Staphylococcus aureus ATCC 43300 using DMSO as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID556862 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 2 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1238341 | Antibacterial activity against Bacillus subtilis NCTC 2116 after 18 hrs by agar diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 25, Issue:16 | Antibacterial activity of diketopiperazines isolated from a marine fungus using t-butoxycarbonyl group as a simple tool for purification. |
| AID572792 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium BN9945 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID323920 | Antibacterial activity against Staphylococcus aureus 2A1-7 fast2 with rplC D159Y and unmapped mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID556671 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 26 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID569310 | Antibacterial activity against Staphylococcus aureus at 75 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID529896 | Antimicrobial activity against Leptospira interrogans serovar Pomona isolate 4 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID524676 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ, penB and mtrR mutant gene assessed as percentage intermediate isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID524883 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ mutant gene assessed as incidence of resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID588217 | FDA HLAED, serum glutamic pyruvic transaminase (SGPT) increase | 2004 | Current drug discovery technologies, Dec, Volume: 1, Issue:4 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. |
| AID545049 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ249 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID1648087 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID694208 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 by CLSI broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 22, Issue:22 | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. |
| AID278244 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-4 with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID556866 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 6 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID278234 | Antimicrobial activity against Salmonella enterica serovar Typhimurium GyrA S21-1 acrAB::Kan with GyrA S83F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID353042 | Antimicrobial activity against Proteus vulgaris at 75 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID565817 | Antimicrobial activity against Neisseria gonorrhoeae isolates by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Update on fusidic acid (CEM-102) tested against Neisseria gonorrhoeae and Chlamydia trachomatis. |
| AID1635004 | Bacteriostatic activity against Pseudomonas aeruginosa assessed as induction of bacteria killing at 80 uM after 3 hrs by time kill assay | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID667262 | Antibacterial activity against Staphylococcus aureus at 500 ug/ml after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. |
| AID569041 | Antibacterial activity against Staphylococcus epidermidis after 24 hrs micro dilution assay | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis, antimicrobial activity and structure-activity relationship study of N,N-dibenzyl-cyclohexane-1,2-diamine derivatives. |
| AID1348087 | Antimicrobial activity against Staphylococcus aureus subsp. aureus ATCC 25923 assessed as zone of inhibition at 50 ug per disc after 24 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID1465956 | Antibacterial activity against Staphylococcus aureus after 20 hrs by broth microdilution method | 2017 | Bioorganic & medicinal chemistry, 06-01, Volume: 25, Issue:11 | Metabolite diversification by cultivation of the endophytic fungus Dothideomycete sp. in halogen containing media: Cultivation of terrestrial fungus in seawater. |
| AID295120 | Antibacterial activity against Micrococcus luteus La 2971 at 30 ug by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID405139 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate assessed as percent susceptible isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID542388 | Antimicrobial activity against Staphylococcus aureus RN4220 transformed with Staphylococcus aureus ST398 plasmid pSCFS3 carrying cfr and fexA genes | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID524887 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing tetM mutant gene in combination with variants of other gene loci assessed as incidence of resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID565074 | Antibacterial activity against CTX-M-14 ESBL producing Proteus mirabilis assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID27795 | AUC (area under curve) after oral dosing by gavage needle at 30 mg/kg in C57BL/6NTac female mice; Not checked | 2002 | Journal of medicinal chemistry, Sep-12, Volume: 45, Issue:19 | Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 2. |
| AID560777 | Antibacterial activity against Staphylococcus aureus TS2921 harboring ddlA Asp102Asn mutation in presence of 100 mM D-Ala-D-Ala, which complements temperature sensitivity after 20 hrs | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID1681022 | Antibacterial activity against Enterobacter aerogenes ATCC 13048 by CLSI method | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID509632 | Antimicrobial activity against Staphylococcus aureus 25 transformant carrying plasmid pKKS25 and expressing erm(T), dfrKtet(L), tet(K), tet(M), mecA and blaZ genes by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID564834 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID206304 | In vitro antibacterial activity against Staphylococcus aureus UBMS 90-3 sensitive | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID396274 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(A), tet(M) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID449361 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by tube dilution technique | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety. |
| AID1566490 | Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation at 1 mM measured after 15 mins by cat-ELCCA relative to control | 2019 | ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5 | Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. |
| AID671554 | Antibacterial activity against Escherichia coli isolate EC155 expressing tetA gene | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID565641 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.10 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =790.8 +/- 90.09 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID548474 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID323918 | Antibacterial activity against Staphylococcus aureus 2A1-1 fast2 with rplC D159Y and unmapped mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID501856 | Antibacterial activity against Corynebacterium pyogenes ATCC 19411 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID556897 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 9 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID524827 | Antibacterial activity against erythromycin susceptible Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID575056 | Antibacterial activity against Vibrio cholerae O1 mTn-321 harboring Ser to Ile mutation at 83 position in gyrA and parC genes by 2-fold agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Reduced expression of the vca0421 gene of Vibrio cholerae O1 results in innate resistance to ciprofloxacin. |
| AID565631 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.15 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =790.8 +/- 90.09 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID320706 | Inhibition of PAD4 by ABPP-based assay | 2008 | Bioorganic & medicinal chemistry, Jan-15, Volume: 16, Issue:2 | Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors. |
| AID516165 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates by CLSi method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID1269975 | Antimicrobial activity against Escherichia coli K-12 MG1655 after 24 hrs by double dilution method | 2015 | MedChemComm, May-01, Volume: 6, Issue:5 | Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity. |
| AID585876 | Antimicrobial activity against Pseudomonas aeruginosa isolate 18 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID496400 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT13-1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 13 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID495749 | Antimicrobial activity against Salmonella enterica serotype Virchow 3464b by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID547541 | Antimicrobial activity against invasive Streptococcus constellatus obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on brain heart infusion agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID477107 | Antimicrobial activity against Penicillium chrysogenum MTCC 1996 at 30 ug/ml after 48 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID547529 | Antimicrobial activity against Streptococcus intermedius obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on brain heart infusion agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID547755 | Antimicrobial activity against invasive Streptococcus intermedius obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID1726845 | Cytotoxicity against human HaCaT cells after 24 hrs by MTT assay | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6 | Sulfonium-based liposome-encapsulated antibiotics deliver a synergistic antibacterial activity. |
| AID278265 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS18 gyrA+ with GyrA S38F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID325483 | Antibacterial activity against Escherichia coli N43 acrA mutant assessed as inhibition of AcrAB efflux pump after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID624609 | Specific activity of expressed human recombinant UGT1A6 | 2000 | Annual review of pharmacology and toxicology, , Volume: 40 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. |
| AID542585 | Antimicrobial activity against plasmid encoded beta-lactamase OXA-58 deficient Acinetobacter radioresistens by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program. |
| AID585869 | Antimicrobial activity against Pseudomonas aeruginosa isolate 15 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID678712 | Inhibition of human CYP1A2 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using ethoxyresorufin as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID532983 | Antibacterial activity against Escherichia coli W3110 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID312017 | Antifungal activity against Beauveria bassiana at 10 ug/disc after 48 hrs by disc diffusion assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae. |
| AID1525331 | Antibacterial activity against Escherichia coli 2271 after 20 hrs by CLSI-based microdilution method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance. |
| AID516162 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as susceptible isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID425582 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID545055 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate CC023 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID532020 | Antibacterial activity against macrolide-lincosamide-streptogramin B-negative, beta-lactamase-positive, methicillin-susceptible Staphylococcus aureus isolate 3 | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Combined antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone-spermine conjugate. |
| AID496396 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID529900 | Antimicrobial activity against Leptospira interrogans serovar Icterohaemorrhagiae isolate 9 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID396504 | Antibacterial activity against Escherichia coli ATCC 25922 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID425596 | Antibacterial activity against extracellular Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease at 0.01 to 10 ug/ml after 3 hrs | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID564831 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID548475 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID323919 | Antibacterial activity against Staphylococcus aureus 2A1-7 fast1 with rplC D159Y and unmapped mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID388087 | Antibacterial activity at Staphylococcus aureus | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents. |
| AID1688655 | Bactericidal activity against Staphylococcus aureus ATCC 29213 incubated for 24 hrs followed by transferring to freshly prepared broth medium and measured after 24 hrs by broth microdilution assay | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID312018 | Antifungal activity against Saccharomyces cerevisiae at 10 ug/disc after 48 hrs by disc diffusion assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae. |
| AID565314 | Antibacterial activity against Mycoplasma genitalium TW10-6G by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID1368273 | Antibacterial activity against Staphylococcus aureus RN4220 by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue:1 | A novel series of enoyl reductase inhibitors targeting the ESKAPE pathogens, Staphylococcus aureus and Acinetobacter baumannii. |
| AID582763 | Antimicrobial activity against eaeA positive verocytotoxin-producing non-O157 Escherichia coli isolates obtained from human assessed as percentage of resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID405924 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus XU212 | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Inhibitors of bacterial multidrug efflux pumps from the resin glycosides of Ipomoea murucoides. |
| AID428273 | Antimicrobial activity against carbapenemase producing Enterobacter sp. assessed as susceptible isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID545047 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ088 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID548527 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID561745 | Antibacterial activity against Methicillin-sensitive Staphylococcus aureus assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID528706 | Antibacterial activity against Streptococcus agalactiae group B clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID322259 | Antibacterial activity against Salmonella typhi by well diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 18, Issue:7 | Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens. |
| AID545051 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ274 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID564826 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID531334 | Antibacterial activity against Pseudomonas aeruginosa TNP030 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID544005 | Antimicrobial activity against Pseudomonas fluorescens isolate C131 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID467963 | Antimicrobial activity against Citrobacter freundii ATCC 8090 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID588210 | Human drug-induced liver injury (DILI) modelling dataset from Ekins et al | 2010 | Drug metabolism and disposition: the biological fate of chemicals, Dec, Volume: 38, Issue:12 | A predictive ligand-based Bayesian model for human drug-induced liver injury. |
| AID567569 | Antimicrobial activity against Staphylococcus aureus RN4220 | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID323028 | Antibacterial activity against Corynebacterium amycolatum after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID565228 | Antimicrobial activity against Mycobacterium chelonae ATCC 35752 by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID544013 | Antimicrobial activity against Pseudomonas putida isolate C231 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID454161 | Antimicrobial activity against Proteus vulgaris MTCC 1771 at 10 ug/ml after 24 hrs by agar diffusion method | 2009 | Bioorganic & medicinal chemistry, Dec-15, Volume: 17, Issue:24 | Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents. |
| AID560224 | Antibacterial activity against Salmonella enterica serovar Typhimurium R200 expressing stm3031 gene deletion mutant by CLSI M7-A7 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Outer membrane protein STM3031 (Ail/OmpX-like protein) plays a key role in the ceftriaxone resistance of Salmonella enterica serovar Typhimurium. |
| AID585873 | Antimicrobial activity against Pseudomonas aeruginosa isolate 17 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID494536 | Antimicrobial activity against Proteus vulgaris NCIM 2813 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494536 | Antimicrobial activity against Proteus vulgaris NCIM 2813 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID442202 | Antibacterial activity against Escherichia coli at 50 mg/mL after 48 hrs by agar plate disc diffusion method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Design, synthesis and docking studies of new furobenzopyranones and pyranobenzopyranones as photoreagent towards DNA and as antimicrobial agents. |
| AID547540 | Antimicrobial activity against invasive Streptococcus constellatus obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence o | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID325013 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 552 isolate with erm(B) resistance gene from patient sinuitis by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID323029 | Antibacterial activity against Corynebacterium minutissimum after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID353049 | Antimicrobial activity against Staphylococcus aureus at 50 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID250271 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH24; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID556869 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 9 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID554876 | Antimicrobial activity against Streptococcus pneumoniae serotype 4 ST 205 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID498362 | Antimicrobial activity against rifampin resistant Klebsiella pneumoniae 52deltaacrR containing isogenic acrR knockout assessed as growth inhibition by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. |
| AID278247 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-4 tolC::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID694391 | Bactericidal activity against Bacillus cereus CECT 148 at 0.2 mg/disk after 24 hrs by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones. |
| AID1382190 | Antibacterial activity against Escherichia coli after 24 hrs by broth microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Synthesis of coumarin-theophylline hybrids as a new class of anti-tubercular and anti-microbial agents. |
| AID1566497 | Binding affinity to miR-21 RNA in human HeLA cells transfected with pmir21 vector incubated for 48 hrs by Dual-Glo luciferase assay | 2019 | ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5 | Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. |
| AID540825 | Antimicrobial activity against acrB::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 5408-cip harboring gyrA D87Y, gyrB E466D, parE V461G mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID572818 | Antimicrobial activity against ramR-deficient Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1325496 | Antibacterial activity against erythromycin-resistant Staphylococcus aureus NRS-70 | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: Modifications at C-12. |
| AID646209 | Antibacterial activity against Enterococcus faecalis ATCC 103 29212 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID285191 | Antimicrobial activity against Escherichia coli M013 mutant with AG100 delta-(lon-hupB-ppiD) dupIS5 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID585859 | Antimicrobial activity against Pseudomonas aeruginosa isolate 10 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID529892 | Antimicrobial activity against Leptospira interrogans isolate 7 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID528918 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli expressing beta-lactamase CTX-M-14 and CTX-M-27 gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID1304847 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate 2 incubated for 16 hrs by broth microdilution method in presence of tiron | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID353041 | Antimicrobial activity against Proteus vulgaris at 50 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID565318 | Antibacterial activity against Mycoplasma genitalium M2300 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID1240026 | Antibacterial activity against Staphylococcus aureus MTCC 96 after 24 hrs by microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID283170 | Increase in biofilm formation of Staphylococcus lugdunensis assessed as percent biofilm forming isolates | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID565309 | Antibacterial activity against Mycoplasma genitalium by quantitative TaqMan PCR method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID554875 | Antimicrobial activity against Streptococcus pneumoniae serotype 18C ST 496 harboring ERY-resistant erm(B) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID558079 | Inhibition of PAR2 gene expression in normal human epidermal keratinocytes at 10 uM after 48 hrs by quantitative RT-PCR | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. |
| AID444057 | Fraction escaping hepatic elimination in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID395367 | Antibacterial activity against Escherichia coli ATCC 11230 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID1366160 | Antibacterial activity against Staphylococcus aureus incubated overnight by two-fold serial dilution method | 2017 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22 | Antibacterial constituents of the plant family Amaryllidaceae. |
| AID671553 | Antibacterial activity against Escherichia coli ATCC 25922 isolate 107 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID501858 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID293954 | Inhibition of human MMP8 | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6 | Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases. |
| AID495750 | Antimicrobial activity against Escherichia coli J5 by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID341059 | Activity of tetracycline efflux transporter TetA(B) in Escherichia coli DH5alpha membrane vesicles assessed as [3H]tetracycline uptake | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate. |
| AID324170 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid PhoU at 25 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID520959 | Antimicrobial activity against Corynebacterium pseudodiphtheriticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID1240020 | Antibacterial activity against Klebsiella pneumoniae MTCC 3384 at 100 ug/ml after 24 hrs by disc diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID1654443 | Antibacterial activity against Paenibacillus larvae ATCC 9545 assessed as reduction in microbial growth by CLSI based broth microdilution method | 2020 | Journal of natural products, 03-27, Volume: 83, Issue:3 | Meliponamycins: Antimicrobials from Stingless Bee-Associated |
| AID429084 | Antibacterial activity against Clostridium difficile CD5 expressing tet(W) gene | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile. |
| AID543350 | Antimicrobial activity against Salmonella serotype Choleraesuis assessed as percent tetracyclin-resistant isolate at 1 to >128 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID584829 | Antibacterial activity against Staphylococcus aureus | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Chip calorimetry for fast and reliable evaluation of bactericidal and bacteriostatic treatments of biofilms. |
| AID283159 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2526 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID278269 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS38 gyrA+ with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID529159 | Antibacterial activity against Pseudomonas aeruginosa 100609 after 20 hrs by broth microdilution assay | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID429058 | Antimicrobial activity against tetracycline-resistant Ureaplasma sp. isolate overexpressing tet(M) gene | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Tetracycline resistance in Ureaplasma spp. and Mycoplasma hominis: prevalence in Bordeaux, France, from 1999 to 2002 and description of two tet(M)-positive isolates of M. hominis susceptible to tetracyclines. |
| AID576111 | Antimicrobial activity against mecA-deficient Staphylococcus sciuri harboring staphylococcus aureus mecA gene assessed as resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. |
| AID694396 | Bactericidal activity against Escherichia coli CECT 100 at 0.2 mg/disk after 24 hrs by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones. |
| AID556678 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 5 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1698036 | Antibacterial activity against Staphylococcus aureus assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID725545 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 20 hrs by liquid microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3 | Discovery of nosokophic acid, a predicted intermediate of moenomycins, from nosokomycin-producing Streptomyces sp. K04-0144. |
| AID285204 | Antimicrobial activity against Escherichia coli AG112 mutant with AG100 marR genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID564809 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID428140 | Antimicrobial activity against Streptococcus pneumoniae PC13 transformant harboring 136-bp deletion in erm(B) gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. |
| AID561515 | Antibacterial activity against Enterococcus faecium by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID556685 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 12 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID629285 | Antibacterial activity against Photobacterium leiognathi Sh1 assessed as inhibition of bacterial luminescence at 0.1 mg/mL after 10 mins by bioluminometry-based chronic action test | 2011 | European journal of medicinal chemistry, Dec, Volume: 46, Issue:12 | Synthesis and biological activity of novel N-cycloalkyl-(cycloalkylaryl)-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-yl)thio]acetamides. |
| AID1360038 | Antimicrobial activity against Bacillus cereus after 18 to 20 hrs by micro broth dilution method | 2018 | European journal of medicinal chemistry, Jun-25, Volume: 154 | Free radical rearrangement synthesis and microbiological evaluation of novel 2-sulfoether-4-quinolone scaffolds as potential antibacterial agents. |
| AID556672 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 27 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID285846 | Antimicrobial activity against erythromycin-resistant Streptococcus pyogenes A-3 transconjugated with erm(B) and tet(M) genes | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID544282 | Antimicrobial activity against Enterococcus faecalis NKH12 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID585849 | Antimicrobial activity against Pseudomonas aeruginosa isolate 5 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1254824 | Antibacterial activity against Bacillus subtilis ATCC 23857 after 12 hrs by agar diffusion method | 2015 | Journal of natural products, Oct-23, Volume: 78, Issue:10 | Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion. |
| AID1061191 | Antimicrobial activity against Staphylococcus aureus MTCC 96 at 100 ug/ml after 24 hrs by disc diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID1243994 | Antimicrobial activity against Aeromonas hydrophila by agar dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents. |
| AID1515695 | Antibacterial activity against Porphyromonas gingivalis 381 assessed as bacterial growth inhibition at 2.25 uM measured after 2 hrs in anaerobic condition by WST1 assay | 2019 | MedChemComm, Jun-01, Volume: 10, Issue:6 | Novel zafirlukast derivatives exhibit selective antibacterial activity against |
| AID565640 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.08 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =790.8 +/- 90.09 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID681031 | TP_TRANSPORTER: uptake in OAT3-expressing S2 cells | 2002 | Japanese journal of pharmacology, Jan, Volume: 88, Issue:1 | Human organic anion transporters mediate the transport of tetracycline. |
| AID1412154 | Bactericidal activity against methicillin-resistant Staphylococcus aureus 15 incubated for 24 hrs followed by replating on Mueller hinton agar plates and measured after 24 hrs | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID554860 | Antimicrobial activity against Streptococcus pneumoniae serotype 14 ST 143 harboring ERY-resistant erm(B) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID558078 | Inhibition of PAR2-mediated SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes at 10 uM after 24 hrs by ELISA | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. |
| AID467968 | Antimicrobial activity against Staphylococcus epidermidis ATCC 14990 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID543366 | Antimicrobial activity against tigecycline-intermediate Aeromonas caviae isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID544271 | Antimicrobial activity against Enterococcus faecalis NKH1 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID613191 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by MTT assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives. |
| AID644018 | Antimicrobial activity against Staphylococcus aureus at 25 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID293955 | Inhibition of human MMP13 | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6 | Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases. |
| AID323012 | Antibacterial activity against drug-resistant Propionibacterium acnes SW101CDA after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID541149 | Antimicrobial activity against soxS::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 104-cip harboring gyrA D87Y,S83F mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID1127620 | Antibacterial activity against fluoroquinolone-resistant Streptococcus pneumoniae D39 NCTC 7466 expressing GyrB K143A/ParE T172A double mutant assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID285201 | Antimicrobial activity against Escherichia coli M104 mutant with AG100 dupIS3 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID572799 | Antimicrobial activity against marA::kan-deficient Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID548524 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID544272 | Antimicrobial activity against Enterococcus faecalis NKH2 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1112106 | Antimicrobial activity against Escherichia coli by agar diffusion test | 2012 | Fitoterapia, Apr, Volume: 83, Issue:3 | Pyrenocines J-M: four new pyrenocines from the endophytic fungus, Phomopsis sp. |
| AID1230065 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2372 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID373750 | Antimicrobial activity against mupirocin-resistant methicillin-resistant Staphylococcus aureus assessed as resistant rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. |
| AID477409 | Antibacterial activity against Staphylococcus aureus NCTC 8325 after 16 to 20 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID565320 | Antibacterial activity against Mycoplasma genitalium M2341 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID585423 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G262-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1688650 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as reduction in bacterial growth incubated for 1 day by paper disk diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID323906 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC S158L mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID1593384 | Growth inhibition of Staphylococcus aureus Newman | 2019 | Journal of medicinal chemistry, 04-11, Volume: 62, Issue:7 | Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. |
| AID1496320 | Cytotoxicity against human THP1 cells after 24 hrs by LDH release assay | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID520960 | Antimicrobial activity against Corynebacterium striatum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID428295 | Antimicrobial activity against Acinetobacter baumannii BM4579 expressing adeIJK genes with pAT807 isolated from patient with urinary tract infection by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID532986 | Antibacterial activity against Pseudomonas aeruginosa NCIM 5029 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID70761 | In vitro minimum inhibitory concentration against Escherichia coli J3272 (tet C efflux). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID556658 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 13 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID404895 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB10 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID556646 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 1 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID299673 | Antibacterial activity against methicillin-resistant Staphylococcus aureus CMAH 0504 at 30 ug/ml by disk diffusion method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID532984 | Antibacterial activity against Escherichia coli MG1655 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID587244 | Antimicrobial activity against Pseudomonas aeruginosa DSM 1128 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID1225389 | Antibacterial activity against Escherichia coli transformed with plasmid carrying MG1655 deltaBC/pXYM by p-iodonitrotetrazolium chloride colorimetric assay | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Enhancement of antibiotic activity against multidrug-resistant bacteria by the efflux pump inhibitor 3,4-dibromopyrrole-2,5-dione isolated from a Pseudoalteromonas sp. |
| AID699539 | Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake at 20 uM by scintillation counting | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10 | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. |
| AID565007 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID531099 | Inhibition of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa TNP090 mutant harboring las and rhl gene at 0.016 ug/ml by Cat-2,3-diO reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID341950 | Antimicrobial activity against Staphylococcus aureus | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15 | Synthesis of some novel imidazole-based dicationic carbazolophanes as potential antibacterials. |
| AID425583 | Antibacterial activity against Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID70922 | In vitro antibacterial activity against Escherichia coli J3272 Tet D | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID477108 | Antimicrobial activity against Trichoderma viride MTCC 167 at 30 ug/ml after 48 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID295117 | Antibacterial activity against Listeria monocytogenes ATCC 15313 at 30 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID348891 | Antibacterial activity against Pseudomonas aeruginosa ATCC 85327 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID556901 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 13 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID694206 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 by CLSI broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 22, Issue:22 | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. |
| AID1672292 | Antifungal activity against Candida albicans assessed as fungal growth inhibition after 24 hrs by CLSI protocol based broth microdilution assay | |||
| AID206394 | Compound was tested for photoinhibition of Staphylococcus aureus(CIP 53156); Sensitive | 1998 | Bioorganic & medicinal chemistry letters, Nov-03, Volume: 8, Issue:21 | Nitroglycosylated meso-arylporphyrins as photoinhibitors of gram positive bacteria. |
| AID206793 | Minimum inhibitory concentration against Staphylococcus aureus | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6 | New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine. |
| AID388083 | Antifungal activity at Benjaminiella poitrasii | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents. |
| AID554872 | Antimicrobial activity against Streptococcus pneumoniae serotype 6B ST 3246 harboring ERY-resistant erm(B) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID278582 | Reduction in Plasmodium falciparum FCK2 in human erythrocyte culture after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID558081 | Inhibition of PAR2-mediated TNFalpha and SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes at 10 uM by ELISA | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. |
| AID556871 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 11 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1261214 | Bacteriostatic activity against Staphylococcus aureus Mu50 after 24 hrs | 2015 | Bioorganic & medicinal chemistry, Nov-01, Volume: 23, Issue:21 | Evaluation of small molecule SecA inhibitors against methicillin-resistant Staphylococcus aureus. |
| AID1593387 | Growth inhibition of Escherichia coli DH5[alpha] | 2019 | Journal of medicinal chemistry, 04-11, Volume: 62, Issue:7 | Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. |
| AID323001 | Antibacterial activity against drug-resistant Propionibacterium acnes P95 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID369667 | Antibacterial activity against Campylobacter jejuni 23-51 assessed as inhibition of CmeABC efflux pump by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID425653 | Renal clearance in human | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15 | Physicochemical determinants of human renal clearance. |
| AID609163 | Antibacterial activity against Escherichia coli assessed as zone of inhibition at 5 uL and 32 degC after 36 hrs by disk diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone. |
| AID386623 | Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells at 100 uM by confocal microscopy | 2008 | Journal of medicinal chemistry, Oct-09, Volume: 51, Issue:19 | Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. |
| AID533662 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring vgaAv positive plasmid CU1 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID565032 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID274302 | Inhibition of protein synthesis in Escherichia coli S30 extracts by coupled transcription-translation assay | 2006 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20 | Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-diamino-piperidinyl triazines. |
| AID749307 | Bactericidal activity against Erwinia carotovora CECT 225 at 0.2 mg/disk after 24 hrs by paper disk-agar diffusion method | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11 | Novel isoquinoline derivatives as antimicrobial agents. |
| AID565018 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID564824 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID340858 | Antimicrobial activity against wild type vancomycin-intermediate resistant Staphylococcus aureus Mu50 by microdilution assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus. |
| AID325014 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 683 isolate with erm(B) resistance gene from patient sputum by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID405082 | Antimicrobial activity against Escherichia coli 33587-TC9 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID1698043 | Antibacterial activity against Shigella boydii assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID556654 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 9 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID546619 | Antimicrobial activity against Escherichia coli harboring beta-lactamase VIM-18 by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID1821095 | Antibacterial activity against Enterococcus faecalis ATCC 19433 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID554653 | Antimicrobial activity against Ureaplasma urealyticum isolate HPA20 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID520958 | Antimicrobial activity against Corynebacterium minutissimum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID535637 | Antimicrobial activity against Group B streptococcus serotype Ib R3 harboring Q557E, A400V mutations in PBP 2X and T567I, G539E mutations in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID554658 | Antimicrobial activity against Ureaplasma parvum isolate UHWP2 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID557797 | Antimicrobial activity against Escherichia coli J53 transconjugated with Proteus mirabilis pHS10 carrying qnrC gene by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID1228688 | Antibacterial activity against Klebsiella pneumoniae 457 harboring CTX-M-15 gene assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID448516 | Antimicrobial activity against Staphylococcus aureus MTCCB 737 after 24 hrs by serial dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents. |
| AID1056852 | Antibacterial activity against CTX-15 expressing Stenotrophomonas maltophilia isolate 125 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID1079932 | Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source] | |||
| AID541856 | Antimicrobial activity against florfenicol-resistant Edwardsiella ictaluri M07-1 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID1335595 | Antibacterial activity against vancomycin susceptible Enterococcus faecalis ATCC 29212 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID501850 | Antibacterial activity against Klebsiella pneumoniae clinical isolate after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID588218 | FDA HLAED, lactate dehydrogenase (LDH) increase | 2004 | Current drug discovery technologies, Dec, Volume: 1, Issue:4 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. |
| AID460631 | Antifungal activity against Penicillium chrysogenum MTCC 1996 at 100 ug/ml after 48 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID212744 | Inhibition of telomerase before assembly using recombinant Tetraymena thermophilia TR and TERT at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID442201 | Antibacterial activity against Staphylococcus aureus at 50 mg/mL after 48 hrs by agar plate disc diffusion method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Design, synthesis and docking studies of new furobenzopyranones and pyranobenzopyranones as photoreagent towards DNA and as antimicrobial agents. |
| AID1820913 | Antibacterial activity against Klebsiella pneumoniae assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID534823 | Antimicrobial activity against nalidixic acid-resistant Campylobacter fetus subsp. fetus IMD523-06 bovine isolate harboring tet(44) and ant(6)-Ib resistance gene in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID1338320 | Antibacterial activity against Enterobacter cloacae PCM 2569 after 20 hrs by microbroth dilution method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | New family of antimicrobial agents derived from 1,4-naphthoquinone. |
| AID283661 | Antimicrobial activity against Haemophilus influenzae CDS40 mutant with acrB insertional inactivation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number. |
| AID1496311 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 725B after 24 hrs | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID285847 | Antimicrobial activity against erythromycin-resistant Streptococcus pyogenes B-83 transconjugated with erm(B) and tet(M) genes | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID646207 | Antibacterial activity against tetracycline- and methicillin-resistant Staphylococcus aureus 161 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID588121 | Antimicrobial activity against Streptococcus suis UD isolated from cerebrospinal fluid of patient with meningitis by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Feb, Volume: 55, Issue:2 | Different genetic elements carrying the tet(W) gene in two human clinical isolates of Streptococcus suis. |
| AID323021 | MBC/MIC ratio of Propionibacterium acnes EG7NS | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID285206 | Antimicrobial activity against Escherichia coli AG112 mutant with marR genotype after 125 generations in absence of tetracycline | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID428270 | Antimicrobial activity against Klebsiella sp. assessed as susceptible isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID572814 | Antimicrobial activity against Salmonella enterica serovar Typhimurium BN18/71 harboring GyrA G81C, acrR mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID278271 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS38 tolC::Kan with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID544019 | Antimicrobial activity against Acinetobacter lwoffii isolate C15 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID556888 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae ATCC 11296 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID522653 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis K9724 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID30552 | Evaluated for the in vitro minimum bactericidal concentration (MBC) against periopathogenic Actinobacillus actinomycetemcommitans bacteria | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1 | Substituted 2-(2-hydroxyphenyl)benzimidazoles as potential agents for the control of periodontal diseases. |
| AID530050 | Antimicrobial activity against Staphylococcus aureus 286607-R1 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID529904 | Antimicrobial activity against Leptospira interrogans serovar Canicola isolate 11 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID1131168 | Antibacterial activity against Bordetella bronchiseptica MB3551 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID539667 | Antimicrobial activity against Streptococcus pneumoniae by well diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno[3,4-b]pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens. |
| AID372898 | Antibacterial activity against sPseudomonas aeruginosa ATCC 13525 after 24 hrs by MTT assay | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. |
| AID358254 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 after 48 hrs by microplate assay | 2001 | Journal of natural products, Oct, Volume: 64, Issue:10 | Antimalarial (+)-trans-hexahydrodibenzopyran derivatives from Machaerium multiflorum. |
| AID1376892 | Antimicrobial activity against Bacillus cereus DSM 4384 assessed as growth inhibition at 7 ug per disc after 24 to 48 hrs (Rvb = 0 millimeter) | |||
| AID569305 | Antibacterial activity against Salmonella typhi at 50 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID307119 | Cytotoxicity against CEM cells after 5 days by MTT method | 2007 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 17, Issue:8 | Newer tetracycline derivatives: synthesis, anti-HIV, antimycobacterial activities and inhibition of HIV-1 integrase. |
| AID1056842 | Antibacterial activity against TEM-1/SHV-12/CTX-15 expressing Enterobacter intermedius isolate 243 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID539668 | Antimicrobial activity against Escherichia coli by well diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno[3,4-b]pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens. |
| AID522646 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis Ohio by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID585422 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W245-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID530234 | Antimicrobial activity against wild-type Mycobacterium bovis BCG by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID545043 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ068 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID530286 | Antimicrobial activity against PR-39-resistant Salmonella enterica serovar Typhimurium LT2 DA10899 harboring Q179Stop mutant gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID585851 | Antimicrobial activity against Pseudomonas aeruginosa isolate 6 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID556693 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes ATCC 15038 harboring pDrive plasmid expressing ampC gene by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1056834 | Antibacterial activity against GIM-1 expressing Pseudomonas aeruginosa isolate 197 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID560780 | Antibacterial activity against Staphylococcus aureus TS5337 harboring ddlA Pro178Ser mutation in fifth-instar silkworm larva infection model assessed as compound concentration per gram of larva causing reduction in survival after 48 hrs post dose at 27 de | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID380474 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 by standard microdilution method | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 | Polyacylated oligosaccharides from medicinal Mexican morning glory species as antibacterials and inhibitors of multidrug resistance in Staphylococcus aureus. |
| AID554879 | Antimicrobial activity against Streptococcus pneumoniae serotype 17 ST 3248 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID1269976 | Antimicrobial activity against Haemophilus influenzae ATCC 51907 after 24 hrs by double dilution method | 2015 | MedChemComm, May-01, Volume: 6, Issue:5 | Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity. |
| AID380477 | Antimicrobial activity against epidemic methicillin-resistant Staphylococcus aureus 15 by standard microdilution method | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 | Polyacylated oligosaccharides from medicinal Mexican morning glory species as antibacterials and inhibitors of multidrug resistance in Staphylococcus aureus. |
| AID285839 | Antimicrobial activity against Streptococcus pyogenes iMLS-A isolate A expressing tet(M), tndX gene | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID530587 | Antimicrobial activity against macrolide-resistant Mycoplasma pneumoniae isolate 1006 with A2603G mutation by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID658545 | Antimycobacterial activity against Salmonella enterica serovar Typhimurium L354 after 24 hrs | 2012 | Journal of natural products, Mar-23, Volume: 75, Issue:3 | Antibacterial acylphloroglucinols from Hypericum olympicum. |
| AID1127623 | Antibacterial activity against fluoroquinolone-resistant Streptococcus pneumoniae D39 NCTC 7466 expressing GyrA S81F/ParC S79Y double mutant assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID406622 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae isolates assessed as percent susceptible isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Prevalence, characteristics, and molecular epidemiology of macrolide and fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae at five tertiary-care hospitals in Korea. |
| AID530287 | Antimicrobial activity against PR-39-resistant sbmA-deficient Salmonella enterica serovar Typhimurium LT2 DA12088 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID594332 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID449359 | Antimicrobial activity against Staphylococcus epidermidis MTCCB 1824 after 24 hrs by tube dilution technique | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety. |
| AID588208 | Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset | 2010 | Molecular pharmaceutics, Oct-04, Volume: 7, Issue:5 | Predicting phospholipidosis using machine learning. |
| AID369448 | Antimicrobial activity against Streptococcus viridans after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID535640 | Antimicrobial activity against Group B streptococcus serotype Ib C2 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID540931 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor SP1 harboring rpsL A262G and C271T mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID1360039 | Antimicrobial activity against Pseudomonas aeruginosa after 18 to 20 hrs by micro broth dilution method | 2018 | European journal of medicinal chemistry, Jun-25, Volume: 154 | Free radical rearrangement synthesis and microbiological evaluation of novel 2-sulfoether-4-quinolone scaffolds as potential antibacterial agents. |
| AID575168 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in marR mutant containing Escherichia coli K-12 3-AG102 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 200 uM by spectrofluorometric a | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID1412153 | Bactericidal activity against Staphylococcus aureus ATCC 6538 incubated for 24 hrs followed by replating on Mueller hinton agar plates and measured after 24 hrs | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID534337 | Antimicrobial activity against Burkholderia pseudomallei Bp216 harboring mini-Tn7T after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID534405 | Antibacterial activity against Escherichia coli EPI300 expressing tet(W) gene assessed as inhibition of bacterial growth at 40 ug/ml after 18 hrs in presence of 2.5 ug/ml efflux pump inhibitor CCCP | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones. |
| AID467966 | Antimicrobial activity against Enterococcus faecalis ATCC 19433 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID1821094 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID565003 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus hominis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID557079 | Antimicrobial activity against multidrug resistant Escherichia coli DH5[alpha] harboring pDrive plasmid by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID572062 | Antibacterial activity against abeS sigma abeS-deficient Acinetobacter baumannii AC0037 by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii. |
| AID1360044 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 18 to 20 hrs by micro broth dilution method | 2018 | European journal of medicinal chemistry, Jun-25, Volume: 154 | Free radical rearrangement synthesis and microbiological evaluation of novel 2-sulfoether-4-quinolone scaffolds as potential antibacterial agents. |
| AID460799 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID1228693 | Antibacterial activity against Stenotrophomonas maltophilia 256 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID250260 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH04; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID520957 | Antimicrobial activity against Corynebacterium jeikeium isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID206122 | In vitro minimum inhibitory concentration against Staphylococcus aureus smith (sensitive). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID530347 | Antimicrobial activity against azide-resistant Escherichia coli J53 harboring pCTX-M carrying blaCTX-M-15 and pQep plasmid carrying qepA2 gene by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID646210 | Antibacterial activity against tetracycline-resistant Enterococcus faecalis 159 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID1412150 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis 57 after 24 hrs by microbroth dilution method | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID556676 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 3 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID278671 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5736 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID572794 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium BN9181 harboring plasmid encoded RamR gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID528728 | Antibacterial activity against Streptococcus pyogenes group A clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID530348 | Antimicrobial activity against azide-resistant Escherichia coli J53 by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID373748 | Antimicrobial activity against mupirocin-resistant methicillin-resistant Staphylococcus aureus by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. |
| AID717271 | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 by CLSI protocol based broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. |
| AID369662 | Antibacterial activity against Escherichia coli EW1b containing pDOB47 | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID561029 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as disruption of plasma membrane permeability at 4 times MIC by ethidium bromide uptake assay | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Antibacterial properties and mode of action of a short acyl-lysyl oligomer. |
| AID341106 | Antibacterial activity against metallo-beta-lactamase VIM12 expressing Escherichia coli 28 isolate from decubitus ulcer infection patient by Etest | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | First occurrence of an Escherichia coli clinical isolate producing the VIM-1/VIM-2 hybrid metallo-beta-lactamase VIM-12. |
| AID373749 | Antimicrobial activity against mupirocin-susceptible methicillin-resistant Staphylococcus aureus assessed as resistant rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. |
| AID532980 | Antibacterial activity against Escherichia coli DH5alpha in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID544027 | Antimicrobial activity against Acinetobacter rhizosphaerae isolate C44 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID644025 | Antimicrobial activity against Pseudomonas aeruginosa at 100 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID644029 | Antimicrobial activity against Klebsiella pneumoniae at 100 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID572151 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBADomegaydhE plasmid containing Escherichia coli multidrug efflux pump YdhE after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID540927 | Antimicrobial activity against Streptomyces coelicolor 1147 after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID285202 | Antimicrobial activity against Escherichia coli M114 mutant with AG100 lon4::IS186 marR::IS2 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID324171 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid vector at 25 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID509865 | Antibacterial activity against Acinetobacter baumannii ATCC 17978 isolated from human CSF | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID561639 | Antibacterial activity against HefC-deficient Helicobacter pylori ARHp80 by CLSI M100-S13 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Pyrazolopyrimidinediones are selective agents for Helicobacter pylori that suppress growth through inhibition of glutamate racemase (MurI). |
| AID406149 | Antimicrobial activity against Chlorella fusca by agar diffusion method | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi. |
| AID429083 | Antibacterial activity against Clostridium difficile clinical isolate expressing tet(M) gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile. |
| AID530751 | Induction of PlytR::lacZ gene expression in Staphylococcus aureus SH1000 at 2 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID554880 | Antimicrobial activity against Streptococcus pneumoniae serotype 6B ST 3249 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID556652 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 7 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID250262 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH06; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID561101 | Antibacterial activity against Pasteurella multocida BB1035 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID646232 | Clearance in Sprague-Dawley rat at 1 mg/kg, iv by LC/MS-MS analysis | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID574167 | Antibacterial activity against Escherichia coli MG1655 grown as planktonic cells after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID646235 | Elimination half life in Sprague-Dawley rat at 10 mg/kg, po by LC/MS-MS analysis | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID396497 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(B), tet(D), tet(E) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID1781495 | Anti-MDR bacterial activity against Micrococcus luteus ML01 assessed as inhibition of bacterial growth incubated for 18 hrs by microplate reader analysis | |||
| AID577443 | Antimicrobial activity against Staphylococcus aureus USA300 isolate harboring pSK41 plasmid expressing tetK gene assessed resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States. |
| AID1254825 | Antibacterial activity against Mycobacterium smegmatis ATCC 607 after 12 hrs by agar diffusion method | 2015 | Journal of natural products, Oct-23, Volume: 78, Issue:10 | Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion. |
| AID680772 | TP_TRANSPORTER: uptake in OAT2-expressing S2 cells | 2002 | Japanese journal of pharmacology, Jan, Volume: 88, Issue:1 | Human organic anion transporters mediate the transport of tetracycline. |
| AID325006 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 237 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID564889 | Antibacterial activity against ompF-deficient Escherichia coli AG100 harboring IS186 insertion in lon3 gene and Tn5 insertion in ycgE gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID323027 | Antibacterial activity against Corynebacterium diphtheriae after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID561103 | Antibacterial activity against Pasteurella multocida BB1037 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID561724 | Antibacterial activity against Enterococcus faecium assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID1056839 | Antibacterial activity against TEM-1/CTX-M-15 expressing Aeromonas caviae isolate 260 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID565441 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.10 ug/ml (Rvb =310.8 +/- 17.10 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID325018 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 918 isolate with erm(B) resistance gene from patient eye by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID565038 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1412158 | Bactericidal activity against Pseudomonas aeruginosa isolate 1 incubated for 24 hrs followed by replating on Mueller hinton agar plates and measured after 24 hrs | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID529898 | Antimicrobial activity against Leptospira weilii isolate 6 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID528701 | Antibacterial activity against Streptococcus viridans clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID315451 | Antibacterial activity against Staphylococcus aureus by microbroth dilution assay | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of 3-arylamino-1-chloropropan-2-ols. |
| AID572810 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium BN18/21 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID529893 | Antimicrobial activity against Leptospira interrogans serovar Bataviae isolate 1 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID585870 | Antimicrobial activity against Pseudomonas aeruginosa isolate 15 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID510747 | Antibacterial activity against Escherichia coli AG102MB harboring pSport1-based acrB gene | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID423155 | Antibacterial activity against Bifidobacterium thermophilum B0256 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Mosaic tetracycline resistance genes and their flanking regions in Bifidobacterium thermophilum and Lactobacillus johnsonii. |
| AID454471 | Antimicrobial activity against Bacillus subtilis MTCC 1789 at 10 ug/ml after 24 hrs by agar diffusion method | 2009 | Bioorganic & medicinal chemistry, Dec-15, Volume: 17, Issue:24 | Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents. |
| AID572059 | Antibacterial activity against Acinetobacter baumannii AC0037 by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii. |
| AID425652 | Total body clearance in human | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15 | Physicochemical determinants of human renal clearance. |
| AID1335592 | Antibacterial activity against methicillin sensitive Staphylococcus aureus ATCC 25213 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID646234 | Elimination half life in Sprague-Dawley rat at 1 mg/kg, iv by LC/MS-MS analysis | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID1158053 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 assessed as compound level causing less than 2% growth after 16 hrs by serial dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla. |
| AID1635003 | Bacteriostatic activity against Pseudomonas aeruginosa assessed as induction of bacteria killing at 80 uM after 60 mins by time kill assay | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID587840 | Antibacterial activity against Streptococcus pneumoniae by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID285840 | Antimicrobial activity against Streptococcus pyogenes cMLS isolate B expressing tet(M), int, Xis gene | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID322992 | Antibacterial activity against drug-resistant Propionibacterium acnes SW26 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID564823 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1079934 | Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source] | |||
| AID1225388 | Antibacterial activity against Escherichia coli transformed with plasmid carrying MG1655 deltaBC/pABM by p-iodonitrotetrazolium chloride colorimetric assay | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Enhancement of antibiotic activity against multidrug-resistant bacteria by the efflux pump inhibitor 3,4-dibromopyrrole-2,5-dione isolated from a Pseudoalteromonas sp. |
| AID1681010 | Antibacterial activity against Bacillus cereus assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID587830 | Antibacterial activity against wild type Staphylococcus aureus Smith ATCC 13709 by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID519140 | Antimicrobial activity against community-acquired methicillin resistant Staphylococcus aureus expressing PVL and mec type IV gene assessed as resistant strains by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. |
| AID442199 | Antimicrobial activity against Bacillus subtilis pretreated 3 hrs before UV photosensitization measured after overnight reincubation under dark condition by agar plate disc diffusion method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Design, synthesis and docking studies of new furobenzopyranones and pyranobenzopyranones as photoreagent towards DNA and as antimicrobial agents. |
| AID644024 | Antimicrobial activity against Pseudomonas aeruginosa at 75 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID554866 | Antimicrobial activity against Streptococcus pneumoniae serotype 19F ST 2917 harboring ERY-resistant erm(B) and mef(E) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID307416 | Antibacterial activity against Staphylococcus aureus isolate | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Syntheses and antibacterial activity of phendioxy substituted cyclic enediynes. |
| AID548257 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID322990 | Antibacterial activity against drug-resistant Propionibacterium acnes SW16 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID522642 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis Vollum 1B by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID278256 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS9 with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID678722 | Covalent binding affinity to human liver microsomes assessed per mg of protein at 10 uM after 60 mins presence of NADPH | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID501866 | Antifungal activity against Penicillium chrysogenum isolates after 48 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID588214 | FDA HLAED, liver enzyme composite activity | 2004 | Current drug discovery technologies, Dec, Volume: 1, Issue:4 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. |
| AID565056 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene and Tn5 insertion in ycgE gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID460630 | Antifungal activity against Candida albicans MTCC 227 at 100 ug/ml after 48 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID522666 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis Texas 2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID447078 | Antibacterial activity against Listeria monocytogenes ATCC 15313 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID532019 | Antibacterial activity against macrolide-lincosamide-streptogramin B-positive, beta-lactamase-positive, methicillin-resistant Staphylococcus aureus ATCC 43300 | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Combined antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone-spermine conjugate. |
| AID574553 | Decrease in PSMbeta1 levels in Staphylococcus aureus Sanger 252 at subinhibitory concentrations after 24 hrs by RP-HPLC/ESI- MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID278683 | Antibacterial activity against Enterococcus faecalis isolate 5745 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID362545 | Antibacterial activity against epidemic methicillin-resistant Staphylococcus aureus 15 after 18 hrs | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. |
| AID1325494 | Antibacterial activity against Staphylococcus aureus Newman | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: Modifications at C-12. |
| AID1681013 | Antibacterial activity against Escherichia coli assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID1442642 | Antibacterial activity against gram-negative Escherichia coli EC155 harboring tet(A) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID556900 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 12 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565037 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID556689 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 16 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID521966 | Antibacterial activity against Campylobacter jejuni assessed as resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID572809 | Antimicrobial activity against Salmonella enterica serovar Typhimurium BN18/21 harboring plasmid encoded RamR gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID278577 | Inhibition of Plasmodium falciparum FCK2 growth as [3H]hypoxanthine uptake after 96 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID516159 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates by CLSi method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID501857 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID694397 | Bactericidal activity against Erwinia carotovora CECT 225 at 0.2 mg/disk after 24 hrs by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones. |
| AID565017 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID323917 | Antibacterial activity against Staphylococcus aureus 2A1-1 fast1 with rplC D159Y and unmapped mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID396272 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(A), tet(D) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID361087 | Antibacterial activity against Klebsiella pneumoniae subsp. pneumoniae ATCC 13833 at 30 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID540213 | Half life in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID325017 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 859 isolate with erm(B) resistance gene from patient bronchoalveolar lavage by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID315448 | Antibacterial activity against Salmonella typhi by microbroth dilution assay | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of 3-arylamino-1-chloropropan-2-ols. |
| AID369446 | Antimicrobial activity against Streptococcus group A after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID278232 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-1 GyrA S83F mutant | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1240013 | Antibacterial activity against Bacillus cereus MTCC 8372 at 50 ug/ml after 24 hrs by disc diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID529895 | Antimicrobial activity against Leptospira interrogans serovar Icterohaemorrhagiae isolate 3 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID565011 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID278670 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5735 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID1250089 | Ratio of MIC for Pseudomonas aeruginosa PAO1 to MIC for mexABCDXY-deficient Pseudomonas aeruginosa PAO1 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID1269978 | Antimicrobial activity against Bacillus cereus ATCC 11778 after 24 hrs by double dilution method | 2015 | MedChemComm, May-01, Volume: 6, Issue:5 | Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity. |
| AID601191 | Cmax in Sprague-Dawley rat at 1 mg/kg, iv administered as single dose measured after 24 to 48 hrs | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID324194 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid PhoU at 50 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID532027 | Antimicrobial activity against Kluyvera georgiana 14751 expressing beta-lactamase CTX-M-78 obtained from bloodstream of patient by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID560250 | Antibacterial activity against Staphylococcus aureus RN4220 harboring aadD and tet(L) gene by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID454158 | Antimicrobial activity against Klebsiella pneumoniae NCIM 2957 at 10 ug/ml after 24 hrs by agar diffusion method | 2009 | Bioorganic & medicinal chemistry, Dec-15, Volume: 17, Issue:24 | Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents. |
| AID1127617 | Antibacterial activity against fluoroquinolone-resistant Streptococcus pneumoniae D39 NCTC 7466 expressing ParE/GyrB K143I mutant assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID278672 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5733 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID544028 | Antimicrobial activity against Acinetobacter lwoffii isolate C141 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID295105 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 30 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID323910 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC G152D, D159Y and G144R mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID362541 | Antibacterial activity against methicillin-resistant Staphylococcus aureus SA1199B after 18 hrs | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. |
| AID632689 | Antibacterial activity against Bacillus subtilis after 24 to 48 hrs by microdilution method | 2011 | Journal of medicinal chemistry, Nov-24, Volume: 54, Issue:22 | Lipophosphonoxins: new modular molecular structures with significant antibacterial properties. |
| AID562472 | Antimicrobial activity against Klebsiella pneumoniae isolate 2641/08 obtained from urine of patient with ischemic cardiomyopathy and several comorbidities by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID561636 | Antibacterial activity against Helicobacter pylori SS1 by CLSI M100-S13 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Pyrazolopyrimidinediones are selective agents for Helicobacter pylori that suppress growth through inhibition of glutamate racemase (MurI). |
| AID425399 | Antibacterial activity against Escherichia coli isolate HM580 isolated from colonic mucosal biopsies of patient with Crohn's disease after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1079938 | Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] | |||
| AID1360043 | Bactericidal activity against Bacillus cereus after 24 hrs by micro broth dilution method | 2018 | European journal of medicinal chemistry, Jun-25, Volume: 154 | Free radical rearrangement synthesis and microbiological evaluation of novel 2-sulfoether-4-quinolone scaffolds as potential antibacterial agents. |
| AID1124943 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as growth inhibition after 16 to 20 hrs by microbroth dilution method | 2014 | Bioorganic & medicinal chemistry, Apr-01, Volume: 22, Issue:7 | Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines. |
| AID369656 | Antibacterial activity against Campylobacter jejuni 15-21 by agar diffusion method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID323904 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC D159Y mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID369444 | Antibacterial activity against penicillin-intermediate Streptococcus pneumoniae after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID1474166 | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index | 2016 | Drug discovery today, Apr, Volume: 21, Issue:4 | DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. |
| AID501860 | Antibacterial activity against Sarcina lutea food isolate after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID1335598 | Antibacterial activity against Bacillus cereus ATCC 11778 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID1431166 | Antibacterial activity against gentamicin-resistant Staphylococcus aureus NRS-108 after 18 hrs by two fold serial dilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: modifications at C12 and C7. |
| AID562796 | Antimicrobial activity against Chlamydia trachomatis J/6276/oflR-rifR2 harboring ompA and rpoB genes | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID420022 | Antibacterial activity against Escherichia coli at 20 mg/mL by agar diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Novel pyridazine derivatives: Synthesis and antimicrobial activity evaluation. |
| AID554862 | Antimicrobial activity against Streptococcus pneumoniae serotype 19F ST 671 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID375939 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 78-13607A after 24 hrs by broth microdilution method | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens. |
| AID585841 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID278254 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS3 acrAB::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID285843 | Antimicrobial activity against tetracycline-susceptible Streptococcus pyogenes cMLS isolate E expressing tet(M), tndX gene | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID1685708 | Antimicrobial activity against Bacillus subtilis assessed as inhibition of bacterial growth incubated for overnight by CLSI method | 2016 | Bioorganic & medicinal chemistry, 06-15, Volume: 24, Issue:12 | Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. |
| AID283556 | Antimicrobial activity against Streptococcus pneumoniae R6 with L4 mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID543360 | Antimicrobial activity against tetracycline-susceptible Aeromonas sp. isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID278857 | Inhibition of metabolic activity in primary human osteoblasts assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID368422 | Antimicrobial activity against Escherichia coli KAM32 pSTVqepA containing qepA gene ligated to pSTV28 plasmid by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID556348 | Antimicrobial activity against macrolide-resistant Mycoplasma pneumoniae clinical isolates obtained from bronchial aspirations expressing 23S rRNA A2063G mutant gene and P1 RFLP type I gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China. |
| AID556690 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes ATCC 15038 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565323 | Antibacterial activity against Mycoplasma genitalium M6285 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID379323 | Antimicrobial activity against Escherichia coli ATCC 25922 | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3 | Novel extracellular diterpenoids with biological activity from the cyanobacterium Nostoc commune. |
| AID561752 | Antibacterial activity against Methicillin-resistant Staphylococcus aureus assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID556679 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 6 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID564890 | Antibacterial activity against ompF-deficient Escherichia coli AG100 harboring IS186 insertion in lon3 gene and Tn5 insertion in ycgE gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID625505 | Antimicrobial activity against Escherichia coli after 24 hrs by spectrophotometry | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Green synthesis and antimicrobial evaluation of some new trifluoromethyl-substituted hexahydropyrimidines by grinding. |
| AID1067611 | Antiamyloidogenic activity in mouse transfected with human amylin/amyloid polypeptide assessed as increase in survival time relative to control | 2013 | Journal of medicinal chemistry, Aug-08, Volume: 56, Issue:15 | A new face for old antibiotics: tetracyclines in treatment of amyloidoses. |
| AID636841 | Antibacterial activity against Staphylococcus aureus at 1 to 10 mg/mL after 24 hrs by agar well diffusion method | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1 | Efficient one-pot preparation of novel fused chromeno[2,3-d]pyrimidine and pyrano[2,3-d]pyrimidine derivatives. |
| AID667399 | Antibacterial activity against Bacillus subtilis at 500 ug/ml after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. |
| AID278581 | Reduction in Plasmodium falciparum FCK2 in human blood cell culture after 96 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID278255 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS3 tolC::Kan with GyrA S83F, D87N, parC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID557078 | Antimicrobial activity against multidrug resistant Escherichia coli DH5[alpha] by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID369655 | Antibacterial activity against Campylobacter jejuni 25-19 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID325443 | Antibacterial activity against Escherichia coli K10 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID428266 | Antimicrobial activity against carbapenemase producing Enterobacteriaceae by CLSI broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID556673 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae ATCC 11296 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID308346 | Antibacterial activity against Bacillus subtilis NCIM 2063 | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID56765 | Inhibition zone when tested against DAP-AT from Escherichia coli in M9-Minimal agar at concentration 300 ug | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8 | Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. |
| AID307417 | Antibacterial activity against Salmonella Typhimurium isolate | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Syntheses and antibacterial activity of phendioxy substituted cyclic enediynes. |
| AID1240030 | Antibacterial activity against Klebsiella pneumoniae MTCC 3384 after 24 hrs by microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID561106 | Antibacterial activity against Pasteurella multocida BB1040 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID539436 | Binding affinity to hydroxyapatite at 10 nM by UV-spectroscopy relative to tetracycline | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | 3-O-phosphate ester conjugates of 17-β-O-{1-[2-carboxy-(2-hydroxy-4-methoxy-3-carboxamido)anilido]ethyl}1,3,5(10)-estratriene as novel bone-targeting agents. |
| AID285194 | Antimicrobial activity against Escherichia coli M064 mutant with AG100 lon1::IS186 acrR::IS genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID70763 | In vitro minimum inhibitory concentration against Escherichia coli PRP-1 (tet A efflux). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID522649 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis Colorado by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID519139 | Antimicrobial activity against community-acquired methicillin resistant Staphylococcus aureus expressing PVL gene and mec type IV gene assessed as susceptible strains by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. |
| AID65068 | Estimated rate of [3H]DHS (Dihydrostreptomycin) uptake in Escherichia coli K12 (ATCC 25868) [pmol/min (optical density unit)E-1] at the C50 was determined; NA is not applicable | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID323031 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1888847 | Antibacterial activity against Staphylococcus aureus 1199 measured after 24 hrs by Muller Hinton broth based MTT assay | 2022 | Bioorganic & medicinal chemistry, 01-15, Volume: 54 | Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor. |
| AID556660 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 15 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1634994 | Antimicrobial activity against Pseudomonas aeruginosa 5482 assessed as reduction in bacterial growth after 20 hrs by drop diffusion test | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID476286 | Antibacterial activity against Escherichia coli MTCC 2939 after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Poly(ethylene glycol) (PEG-400) as an alternative reaction solvent for the synthesis of some new 1-(4-(4'-chlorophenyl)-2-thiazolyl)-3-aryl-5-(2-butyl-4-chloro-1H-imidazol-5yl)-2-pyrazolines and their in vitro antimicrobial evaluation. |
| AID460627 | Antifungal activity against Aspergillus niger MTCC 1781 at 100 ug/ml after 48 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID278861 | Inhibition of metabolic activity in HeLa cells assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID565330 | Antibacterial activity against Mycoplasma genitalium M6284 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID425604 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM615 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 10% compound Cmax a | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID556886 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 26 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID547535 | Antimicrobial activity against invasive Streptococcus anginosus obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on brain heart infusion agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID444051 | Total clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID565313 | Antibacterial activity against Mycoplasma genitalium TW10-5G by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID688532 | Antibacterial activity against vancomycin-resistant Enterococcus faecium VRE1 | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Antibacterial spirobisnaphthalenes from the North American cup fungus Urnula craterium. |
| AID547522 | Antimicrobial activity against Streptococcus constellatus obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of 5% def | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID278682 | Antibacterial activity against Enterococcus faecium isolate 5753 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID534338 | Antimicrobial activity against Burkholderia pseudomallei Bp250 harboring mini-Tn7T-bpeA+B+ -oprB+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID530237 | Antimicrobial activity against wild-type Mycobacterium smegmatis SMR5 by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID532763 | Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing ramA::aph mutant by broth dilution method in presence of chlorpromazine | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. |
| AID556647 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 2 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID532985 | Antibacterial activity against Escherichia coli MG1655 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID561112 | Antibacterial activity against Pasteurella multocida BB1046 harboring plasmid pB1003 bearing blaROB-1 gene and plasmid pB1002 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID565429 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 assessed as biofilm formation at 0.05 to 0.10 ug/ml | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID524873 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing mtrR mutant gene assessed as incidence of resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID539670 | Antimicrobial activity against Salmonella typhi by well diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno[3,4-b]pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens. |
| AID562783 | Antimicrobial activity against Chlamydia suis S45/rifR harboring rpoB gene | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID601267 | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg administered as single dose | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID548740 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID562809 | Antimicrobial activity against Escherichia coli J53 | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID569040 | Antibacterial activity against Staphylococcus aureus after 24 hrs micro dilution assay | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis, antimicrobial activity and structure-activity relationship study of N,N-dibenzyl-cyclohexane-1,2-diamine derivatives. |
| AID540835 | Antimicrobial activity against Salmonella enterica serovar enteritidis isolate 104 harboring gyrA D87Y mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID278242 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-3 acrAB::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID562810 | Antimicrobial activity against Escherichia coli J53 harboring pEK499 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID348890 | Antibacterial activity against Enterococcus faecalis ATCC 29737 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID405453 | Antibacterial activity against Pseudomonas aeruginosa PAOdeltamutS by Etest | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Influence of high mutation rates on the mechanisms and dynamics of in vitro and in vivo resistance development to single or combined antipseudomonal agents. |
| AID1593385 | Growth inhibition of Bacillus subtilis 168 | 2019 | Journal of medicinal chemistry, 04-11, Volume: 62, Issue:7 | Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. |
| AID409960 | Inhibition of bovine brain MAOB | 2008 | Journal of medicinal chemistry, Nov-13, Volume: 51, Issue:21 | Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. |
| AID475505 | Binding affinity to amyloid beta (1 to 42) oligomers by change in fluorescence at 100 uM after 10 mins | 2009 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 19, Issue:17 | A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta. |
| AID556691 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes ATCC 15038 harboring pDrive plasmid by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID332075 | Antibacterial activity against Pseudomonas aeruginosa by agar dilution method | 2008 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 18, Issue:11 | Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors. |
| AID323024 | MBC/MIC ratio of Propionibacterium acnes SW101T | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID448512 | Antimicrobial activity against Escherichia coli MTCCB 1652 at 30 ug/mL after 16 to 20 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents. |
| AID1182955 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method | 2014 | Journal of natural products, Jul-25, Volume: 77, Issue:7 | Trimeric anthracenes from the endophytic fungus Stemphylium globuliferum. |
| AID556682 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 9 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID448511 | Antimicrobial activity against Staphylococcus epidermidis MTCCB 1824 at 30 ug/mL after 16 to 20 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents. |
| AID460625 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 50 ug/ml after 24 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID406148 | Antimicrobial activity against Microbotryum violaceum by agar diffusion method | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi. |
| AID1906415 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as reduction in microbial growth incubated for 24 hrs by microbroth dilution method | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Amphiphilic cyclic peptide [W |
| AID542387 | Antimicrobial activity against Staphylococcus aureus RN4220 | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID554656 | Antimicrobial activity against Ureaplasma parvum isolate UHWJM after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID278248 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS1 with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1079949 | Proposed mechanism(s) of liver damage. [column 'MEC' in source] | |||
| AID556648 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 3 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID625292 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID237416 | Distribution coeeficient for the compound at pH7.4 (Log D7.4) | 2004 | Journal of medicinal chemistry, Jul-29, Volume: 47, Issue:16 | Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction. |
| AID678446 | Antibacterial activity against Bacillus subtilis at 12 ug/well after 24 hrs by agar well diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. |
| AID1525330 | Antibacterial activity against methicillin-resistant Enterococcus faecium 1092 after 20 hrs by CLSI-based microdilution method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance. |
| AID325988 | Antimicrobial activity against Streptococcus sp.11923/96 | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci. |
| AID508594 | Antibacterial activity against ciprofloxacin-susceptible Salmonella enteritidis 1A-revertC2 harboring gyrA D87Y/S83F mutant, parC D79N mutant, soxR R133C/R20H mutant, soxS E52K mutant and marA I111N/H115Q mutant gene after 70 passages by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID585866 | Antimicrobial activity against Pseudomonas aeruginosa isolate 13 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1360037 | Antimicrobial activity against Staphylococcus aureus after 18 to 20 hrs by micro broth dilution method | 2018 | European journal of medicinal chemistry, Jun-25, Volume: 154 | Free radical rearrangement synthesis and microbiological evaluation of novel 2-sulfoether-4-quinolone scaffolds as potential antibacterial agents. |
| AID476287 | Antibacterial activity against Salmonella typhi MTCC 98 after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Poly(ethylene glycol) (PEG-400) as an alternative reaction solvent for the synthesis of some new 1-(4-(4'-chlorophenyl)-2-thiazolyl)-3-aryl-5-(2-butyl-4-chloro-1H-imidazol-5yl)-2-pyrazolines and their in vitro antimicrobial evaluation. |
| AID572789 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium 543SA98 harboring GyrA S83Y mutant gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID629283 | Antibacterial activity against Photobacterium leiognathi Sh1 assessed as inhibition of bacterial luminescence at 0.025 mg/mL after 10 mins by bioluminometry-based acute action test | 2011 | European journal of medicinal chemistry, Dec, Volume: 46, Issue:12 | Synthesis and biological activity of novel N-cycloalkyl-(cycloalkylaryl)-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-yl)thio]acetamides. |
| AID587846 | Half life in Sprague-Dawley rat at 1 mg/kg, iv and 10 mg/kg, po | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID556665 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 20 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID368418 | Antimicrobial activity against multidrug-resistant Escherichia coli C316 pHPA containing mutated GyrA gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID565068 | Antibacterial activity against CTX-M-15 and SHV-12 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID572800 | Antimicrobial activity against soxR::kan-deficient Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1412149 | Antibacterial activity against Staphylococcus epidermidis ATCC 35984 after 24 hrs by microbroth dilution method | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID323006 | Antibacterial activity against drug-resistant Propionibacterium acnes SW54EA after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID531331 | Inhibition of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa TNP090 mutant harboring las and rhl gene at 0.06 ug/ml by Cat-2,3-diO reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID644019 | Antimicrobial activity against Staphylococcus aureus at 50 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID396032 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pAP3 plasmid containing Enterobacter aerogenes acrR gene by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID1061193 | Antimicrobial activity against Bacillus cereus MTCC 8372 at 100 ug/ml after 24 hrs by disc diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID1821096 | Antibacterial activity against Salmonella enterica ATCC 14028 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID543361 | Antimicrobial activity against tetracycline-nonsusceptible Aeromonas sp. isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID1079935 | Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source] | |||
| AID1756236 | Antibacterial activity against Bacillus subtilis 168 assessed as bacterial growth inhibition measured after 16 hrs by serial dilution method | 2021 | Journal of natural products, 02-26, Volume: 84, Issue:2 | Hydrated Rubrolides from the New Zealand Tunicate |
| AID624606 | Specific activity of expressed human recombinant UGT1A1 | 2000 | Annual review of pharmacology and toxicology, , Volume: 40 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. |
| AID548472 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID561111 | Antibacterial activity against Pasteurella multocida BB1045 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID565030 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1431163 | Antibacterial activity against aminoglycosides/tetracycline-resistant Staphylococcus aureus NRS-1 after 18 hrs by two fold serial dilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: modifications at C12 and C7. |
| AID575677 | Antibacterial activity against Listeria monocytogenes isolated from humans harboring tet(M) gene | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Antimicrobial resistance of Listeria monocytogenes strains isolated from humans in France. |
| AID323018 | Antibacterial activity against drug-resistant Propionibacterium acnes P95 after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID250306 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH21; I=Intermediate | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID206119 | In vitro minimum inhibitory concentration against Staphylococcus aureus UBMS 88-7 (tet K efflux). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID1905202 | Antibacterial activity against MDR-methicillin-resistant Staphylococcus aureus ATCC BAA-44 assessed as reduction in bacterial growth measured after 18 hrs by broth microdilution method | 2022 | Journal of medicinal chemistry, 04-14, Volume: 65, Issue:7 | Spermine-Conjugated Short Proline-Rich Lipopeptides as Broad-Spectrum Intracellular Targeting Antibacterial Agents. |
| AID1265630 | Antibacterial activity against Staphylococcus aureus SG511 after 24 hrs by broth microdilution method | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Dimeric Octaketide Spiroketals from the Jellyfish-Derived Fungus Paecilomyces variotii J08NF-1. |
| AID554659 | Antimicrobial activity against Ureaplasma parvum SV1 isolate UHWQ3 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID1730999 | Antibacterial activity against Bacillus subtilis168 assessed as inhibition of bacterial growth measured after 18 hrs by two fold serial dilution method | 2021 | European journal of medicinal chemistry, Mar-05, Volume: 213 | Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules. |
| AID587849 | Antibacterial activity against Escherichia coli ATCC 25922 infected in iv dosed mouse septicemia model assessed as mouse protection after 48 hrs | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID323011 | Antibacterial activity against drug-resistant Propionibacterium acnes SP64E after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID396028 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID287372 | Antibacterial activity against Staphylococcus aureus after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID543363 | Antimicrobial activity against tetracycline-nonsusceptible Vibrio sp. Isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID609167 | Antifungal activity against Yarrowia lipolytica assessed as zone of inhibition at 5 uL and 28 degC after 36 hrs by disk diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone. |
| AID521967 | Antibacterial activity against Campylobacter coli assessed as resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID1231527 | Antibacterial activity against Escherichia coli CECT 405 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter broth dilution method | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antibacterial activities of cadiolides A, B and C and analogues. |
| AID561102 | Antibacterial activity against Pasteurella multocida BB1036 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID765060 | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. |
| AID278267 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS18 tolC::Kan with GyrA S38F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID509869 | Antibacterial activity against Acinetobacter baumannii isolate 4860 isolated from human urine | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID548253 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID70928 | In vitro antibacterial activity against Escherichia coli UBMS 88-1 Tet B | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID1781494 | Anti-MDR bacterial activity against Enterococcus faecium CCARM 5203 assessed as inhibition of bacterial growth incubated for 18 hrs by microplate reader analysis | |||
| AID456849 | Antimicrobial activity against Staphylococcus epidermidis after 24 hrs by microdilution assay | 2010 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3 | Synthesis and antibacterial activity of benzyl-[3-(benzylamino-methyl)-cyclohexylmethyl]-amine derivatives. |
| AID565634 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 planktonic cells assessed as bacterial count at 0.08 ug/ml (Rvb =791.7 +/- 44.10 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID739304 | Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 assessed as growth inhibition by CLSI broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. |
| AID325987 | Antimicrobial activity against Streptococcus sp. 782/96 | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci. |
| AID375434 | Displacement of [3H]PSB0413 from human platelet P2Y12 receptor at 10 uM | 2009 | Journal of medicinal chemistry, Jun-25, Volume: 52, Issue:12 | High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. |
| AID540816 | Antimicrobial activity against marA::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 104-cip harboring gyrA D87Y,S83F mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID395372 | Antibacterial activity against Bacillus cereus ATCC 7064 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID496883 | Inhibition of amyloid beta (1-40) aggregation by thioflavin T based fluorometric assay | 2010 | Journal of medicinal chemistry, Aug-26, Volume: 53, Issue:16 | Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy. |
| AID601269 | Antimicrobial activity against tetracycline-susceptible Staphylococcus aureus Smith isolate 100 infected in iv dosed mouse systemic infection model assessed as survival of mouse administered 60 mins post infection measured up to 48 hrs | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID1360042 | Bactericidal activity against Staphylococcus aureus after 24 hrs by micro broth dilution method | 2018 | European journal of medicinal chemistry, Jun-25, Volume: 154 | Free radical rearrangement synthesis and microbiological evaluation of novel 2-sulfoether-4-quinolone scaffolds as potential antibacterial agents. |
| AID1304849 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate 2 incubated for 16 hrs by broth microdilution method in presence of Fe2+ | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID531098 | Inhibition of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa TNP090 mutant harboring las and rhl gene at 0.03 ug/ml by Cat-2,3-diO reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID562788 | Antimicrobial activity against Chlamydia muridarum MoPn/rifRoflR harboring ompA and rpoB genes | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID534342 | Antimicrobial activity against Burkholderia pseudomallei Bp58 harboring deleted bpeR::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID323909 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC G152D and G155R mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID1442628 | Antibacterial activity against gram-negative Burkholderia cenocepacia BC240 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID477109 | Antimicrobial activity against Candida albicans MTCC 227 at 30 ug/ml after 48 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID477104 | Antimicrobial activity against Bacillus megaterium MTCC 1684 at 10 ug/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID528705 | Antibacterial activity against Streptococcus mitis clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID575146 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS123 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID1820911 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID561638 | Inhibition of MurI in flaA mutant Helicobacter pylori Hp80.2 overexpressing MurI gene assessed as microbial growth inhibition by CLSI M100-S13 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Pyrazolopyrimidinediones are selective agents for Helicobacter pylori that suppress growth through inhibition of glutamate racemase (MurI). |
| AID278239 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-2 tolC::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID508592 | Antibacterial activity against ciprofloxacin-resistant Salmonella enteritidis 104 harboring gyrA D87Y/S83F mutant, soxR R20H mutant and soxS E52K mutant gene after 200 passages by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID283158 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2492 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID540837 | Antimicrobial activity against Salmonella enterica serovar enteritidis isolate 5408 harboring gyrA D87Y mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID585433 | Antimicrobial activity against Escherichia coli DH5[alpha] by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID516161 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as resistant isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID557076 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes ATCC 15038 harboring pACM204 plasmid by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID557084 | Antimicrobial activity against multidrug resistant Escherichia coli ATCC 35218 harboring pDrive plasmid expressing ampC gene by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID325020 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 1016 isolate with erm(B) resistance gene from patient blood by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID449364 | Antimicrobial activity against Escherichia coli MTCCB 1652 at 30 ug/mL after 16 to 20 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety. |
| AID678445 | Antibacterial activity against Micrococcus luteus at 12 ug/well after 24 hrs by agar well diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. |
| AID353048 | Antimicrobial activity against Staphylococcus aureus at 25 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID495751 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID250263 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH07; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID395374 | Antibacterial activity against Listeria monocytogenes ATCC 15313 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID565033 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID212743 | Inhibition of telomerase after assembly using recombinant Tetraymena thermophilia TR and TERT at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID644016 | Antimicrobial activity against Bacillus subtilis at 75 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID1230066 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2691 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID565036 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID522656 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis 17T5 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID560772 | Antibacterial activity against Staphylococcus aureus RN4220 after 20 hrs | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID325026 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 759 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID587845 | Volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv and 10 mg/kg, po | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID1551809 | Antibacterial activity against Listeria innocua incubated for 18 hrs post 30 mins pre-diffusion by disk diffusion method | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID1465957 | Antibacterial activity against Staphylococcus epidermidis after 20 hrs by broth microdilution method | 2017 | Bioorganic & medicinal chemistry, 06-01, Volume: 25, Issue:11 | Metabolite diversification by cultivation of the endophytic fungus Dothideomycete sp. in halogen containing media: Cultivation of terrestrial fungus in seawater. |
| AID477101 | Antimicrobial activity against Staphylococcus aureus MTCC 96 at 10 ug/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID1412155 | Bactericidal activity against Staphylococcus epidermidis ATCC 35984 incubated for 24 hrs followed by replating on Mueller hinton agar plates and measured after 24 hrs | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID1585462 | Antibacterial activity against oxacillin/tetracycline-resistant Staphylococcus aureus NRS-100 measured after 16 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents. |
| AID699540 | Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake at 20 uM incubated for 5 mins by scintillation counting | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10 | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. |
| AID561104 | Antibacterial activity against Pasteurella multocida BB1038 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID404951 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus sp. assessed as percent resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID588113 | Antimicrobial activity against Neisseria gonorrhoeae clinical isolates assessed as percent resistant isolates after 24 hrs by agar dilution method | 2011 | Antimicrobial agents and chemotherapy, Feb, Volume: 55, Issue:2 | Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. |
| AID1525333 | Antibacterial activity against Streptococcus pneumoniae 911 after 20 hrs by CLSI-based microdilution method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance. |
| AID561726 | Antibacterial activity against Enterococcus faecalis assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID546209 | Antimicrobial activity against Staphylococcus aureus 2171 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Identification of the novel dfrK-carrying transposon Tn559 in a porcine methicillin-susceptible Staphylococcus aureus ST398 strain. |
| AID594273 | Antimicrobial activity against Bacillus subtilis NCIM 2063/ATCC 6633 at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID278664 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 595 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID522660 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis BA1086 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID559340 | Antimicrobial activity against Shigella flexneri harboring tetA gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID1566489 | Inhibition of biotinylated pre-let-7d microRNA (unknown origin) maturation preincubated for 15 mins followed by Pre-let-7d addition and measured after 5 hrs by cat-ELCCA | 2019 | ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5 | Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. |
| AID501846 | Antibacterial activity against Escherichia coli clinical isolate after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID572594 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium 902SA92 harboring plasmid encoded RamR gene, GyrA S83A and D87N, GyrB S464F and ParC S80I mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID556677 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 4 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1072992 | Bactericidal activity against Porphyromonas gingivalis ATCC 33277 after 3 days | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3 | Pyrano-isoflavans from Glycyrrhiza uralensis with antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis. |
| AID325449 | Antibacterial activity against Staphylococcus aureus ATCC 3556 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID1442629 | Antibacterial activity against gram-positive Enterococcus faecalis EFs327 harboring tet(M) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID396270 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(M) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID287375 | Antibacterial activity against Micrococcus luteus after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID353053 | Antimicrobial activity against Salmonella typhi at 50 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID1848342 | Antibiofilm activity against Porphyromonas gingivalis ATCC 33277 assessed as inhibition of biofilm at 100 uM measured after 48 hrs by safranin staining relative to control | |||
| AID358253 | Antibacterial activity against Staphylococcus aureus ATCC 6535 after 48 hrs by microplate assay | 2001 | Journal of natural products, Oct, Volume: 64, Issue:10 | Antimalarial (+)-trans-hexahydrodibenzopyran derivatives from Machaerium multiflorum. |
| AID587836 | Antibacterial activity against tetracycline-resistant Escherichia coli isolate 155 harboring tet(A) gene by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID283554 | Antimicrobial activity against Streptococcus pneumoniae PC13 isolate with L4 69GTG71 to TPS mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID524826 | Antibacterial activity against erythromycin resistant Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID564827 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID520395 | Antibacterial activity against erm(B) and mef(E)-positive Streptococcus pneumoniae isolate Sweden 15A-25 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID1781493 | Anti-MDR bacterial activity against Enterococcus faecalis CCARM 5172 assessed as inhibition of bacterial growth incubated for 18 hrs by microplate reader analysis | |||
| AID544277 | Antimicrobial activity against Enterococcus faecalis NKH7 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID341947 | Antimicrobial activity against Proteus mirabilis | 2008 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 18, Issue:15 | Synthesis of some novel imidazole-based dicationic carbazolophanes as potential antibacterials. |
| AID559592 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 selected in presence of Ceftazidime by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID613638 | Antimicrobial activity against Staphylococcus aureus SG 511 after 24 hrs by microtiter plate based MIC assay | 2011 | Journal of natural products, Aug-26, Volume: 74, Issue:8 | Antibacterial polyketides from the jellyfish-derived fungus Paecilomyces variotii. |
| AID574543 | Activity of Quorum sensing agr in community-associated methicillin-resistant Staphylococcus aureus USA300 assessed as PSMalpha expression after 8 hrs by qRT-PCR | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID529456 | Antimicrobial activity against Klebsiella pneumoniae containing PFGE clone A expressing beta-lactamase Oxa-48, TEM-1, SHV-12 and Oxa-9 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. |
| AID562786 | Antimicrobial activity against Chlamydia trachomatis L2/oflR-rifR1 harboring ompA and rpoB genes | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID353040 | Antimicrobial activity against Proteus vulgaris at 25 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID323026 | Antibacterial activity against Corynebacterium jeikeium after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID278229 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21 gyrA+ | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID524652 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ and penB mutant gene assessed as incidence of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID568329 | Antimicrobial activity against wild type Escherichia coli by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID1442626 | Antibacterial activity against gram-negative Acinetobacter baumannii AB250 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID565006 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1055423 | Antibacterial activity against Bacillus subtilis 168 trpC2 assessed as growth inhibition by broth microdilution method | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Inducing secondary metabolite production by the endophytic fungus Fusarium tricinctum through coculture with Bacillus subtilis. |
| AID360857 | Antibacterial activity against Stenotrophomonas maltophilia ATCC 13637 at 30 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID501859 | Antibacterial activity against Staphylococcus aureus food isolate after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID1678766 | Antibacterial activity against Escherichia coli ATCC 25922 using DMSO as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID1698049 | Antibacterial activity against Enterobacter aerogenes assessed as inhibition of bacterial growth incubated for overnight by CLSI based method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID1821097 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID524886 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ, penB and mtrR mutant gene assessed as incidence of resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID1240017 | Antibacterial activity against Escherichia coli MTCC 724 at 50 ug/ml after 24 hrs by disc diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID556865 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 5 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID322997 | Antibacterial activity against drug-resistant Propionibacterium granulosum NCTC-11865 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID556884 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 24 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1412147 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by microbroth dilution method | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID679401 | TP_TRANSPORTER: inhibition of PAH uptake (PAH: 5 uM, Tetracycline: 1000 uM) in OAT1-expressing S2 cells | 2002 | Japanese journal of pharmacology, Jan, Volume: 88, Issue:1 | Human organic anion transporters mediate the transport of tetracycline. |
| AID369654 | Antibacterial activity against Campylobacter jejuni 25-19 cmeB:: Kanamycin-resistant mutant by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID70766 | In vitro minimum inhibitory concentration against Escherichia coli UBMS 90-5 (sensitive). | 1994 | Journal of medicinal chemistry, Jan-07, Volume: 37, Issue:1 | Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines. |
| AID325448 | Antibacterial activity against Staphylococcus aureus Mu50 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID405930 | Antimicrobial activity against multidrug-resistant Staphylococcus aureus over expressing NorA MDR efflux pump | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Inhibitors of bacterial multidrug efflux pumps from the resin glycosides of Ipomoea murucoides. |
| AID477106 | Antimicrobial activity against Aspergillus flavus MTCC 2501 at 30 ug/ml after 48 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID353046 | Antimicrobial activity against Proteus mirabilis at 75 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID564818 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID530052 | Antimicrobial activity against Staphylococcus aureus RN4220 expressing gyrB D437N mutant gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID575678 | Antibacterial activity against Listeria monocytogenes isolated from humans harboring int-tn gene | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Antimicrobial resistance of Listeria monocytogenes strains isolated from humans in France. |
| AID542584 | Antimicrobial activity against Acinetobacter radioresistens 251-39C expressing beta-lactamase OXA-133 by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program. |
| AID565452 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.05 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =413.7 +/- 24.47 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID565814 | Antimicrobial activity against Neisseria gonorrhoeae assessed as susceptible isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Update on fusidic acid (CEM-102) tested against Neisseria gonorrhoeae and Chlamydia trachomatis. |
| AID575144 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID718416 | Antibacterial activity against log-phase methicillin-sensitive Staphylococcus aureus 8325-4 assessed as growth inhibition after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. |
| AID1228690 | Antibacterial activity against Pseudomonas aeruginosa 555 BAA-47 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID477102 | Antimicrobial activity against Bacillus subtilis MTCC 1789 at 10 ug/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID1252237 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 | 2015 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 25, Issue:21 | Rapid synthesis and antimicrobial activity of novel 4-oxazolidinone heterocycles. |
| AID739305 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus 8325-4 assessed as growth inhibition by CLSI broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. |
| AID587837 | Antibacterial activity against Klebsiella pneumoniae ATCC 13883 by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID561729 | Antibacterial activity against Enterococcus faecalis assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID449358 | Antimicrobial activity against Staphylococcus aureus MTCCB 737 after 24 hrs by tube dilution technique | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety. |
| AID489651 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID530530 | Induction of Ppbp2::lacZ gene expression in Staphylococcus aureus SH1000 at 2 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID429085 | Antibacterial activity against Clostridium difficile CD37 harboring tet(M) gene from Clostridium difficile CD5 | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile. |
| AID565322 | Antibacterial activity against Mycoplasma genitalium M6280 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID1335604 | Antifungal activity against Candida albicans ATCC 90028 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID699541 | Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake at 20 uM incubated for 5 mins by scintillation counting | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10 | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. |
| AID1634990 | Antimicrobial activity against Staphylococcus epidermidis assessed as reduction in bacterial growth after 20 hrs by drop diffusion test | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID325005 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 897 isolate with erm(B) resistance gene from patient bronchoalveolar lavage by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID585868 | Antimicrobial activity against Pseudomonas aeruginosa isolate 14 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID565449 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.10 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =413.7 +/- 24.47 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID528707 | Antibacterial activity against Streptococcus pyogenes group A clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID532981 | Antibacterial activity against Escherichia coli DH5alpha | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1566488 | Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation preincubated for 15 mins followed by pre-miRNA-21 addition and measured after 5 hrs by cat-ELCCA | 2019 | ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5 | Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. |
| AID557080 | Antimicrobial activity against multidrug resistant Escherichia coli DH5[alpha] harboring pDrive plasmid expressing ampC gene by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID66587 | In vitro antibacterial activity against Enterococcus ATCC 29212 | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID477100 | Antimicrobial activity against Klebsiella pneumoniae NCIM 2957 at 10 ug/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID528790 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae expressing beta-lactamase CTX-M-3, CTX-M-15 and CTX-M-55 gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID509866 | Antibacterial activity against Acinetobacter baumannii isolate 510 isolated from human sputum | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID529903 | Antimicrobial activity against Leptospira kirschneri serovar Grippotyphosa isolate 13 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID528704 | Antibacterial activity against Streptococcus intermedius clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID534165 | Antimicrobial activity against Campylobacter jejuni by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Comparison of disk diffusion and agar dilution methods for erythromycin, ciprofloxacin, and tetracycline susceptibility testing of Campylobacter coli and for tetracycline susceptibility testing of Campylobacter jejuni subsp. jejuni. |
| AID1112105 | Antialgal activity against 'Chlorella' fusca by agar diffusion test | 2012 | Fitoterapia, Apr, Volume: 83, Issue:3 | Pyrenocines J-M: four new pyrenocines from the endophytic fungus, Phomopsis sp. |
| AID312015 | Antifungal activity against Colletotrichum acutatum at 10 ug/disc after 48 hrs by disc diffusion assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae. |
| AID325007 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 415 isolate with erm(B) resistance gene from patient blood by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID454476 | Antimicrobial activity against Trichoderma viride MTCC 167 at 10 ug/ml after 48 hrs by agar diffusion method | 2009 | Bioorganic & medicinal chemistry, Dec-15, Volume: 17, Issue:24 | Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents. |
| AID529901 | Antimicrobial activity against Leptospira interrogans serovar Icterohaemorrhagiae isolate 10 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID323004 | Antibacterial activity against drug-resistant Propionibacterium acnes P429:1 (SC) after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1347487 | Antibacterial activity against Staphylococcus epidermidis assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID765063 | Antimicrobial activity against methicillin-sensitive Staphylococcus aureus 8325-4 by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. |
| AID206302 | In vitro antibacterial activity against Staphylococcus aureus UBMS 88-7 Tet K | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID1131161 | Antibacterial activity against Pseudomonas aeruginosa MB2245 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID528789 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli expressing beta-lactamase CTX-M-3, CTX-M-15 and CTX-M-55 gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID348883 | Antibacterial activity against Bacillus subtilis ATCC 465 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID1056850 | Antibacterial activity against TEM-1/SHV-12 expressing Klebsiella pneumoniae isolate 303 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID353051 | Antimicrobial activity against Staphylococcus aureus at 100 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID532676 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as susceptible isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID562787 | Antimicrobial activity against Chlamydia suis R19/tetR harboring tet(C) allele | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID1571235 | Inhibition of planktonic growth of Porphyromonas gingivalis ATCC 33277 at 40 uM by standard optical density assay relative to control | |||
| AID600726 | Antibacterial activity against Xanthomonas campestris pvs. at 10 ug/disc after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Urea/thiourea derivatives of quinazolinone-lysine conjugates: synthesis and structure-activity relationships of a new series of antimicrobials. |
| AID749311 | Bactericidal activity against Staphylococcus aureus CECT 86 at 0.2 mg/disk after 24 hrs by paper disk-agar diffusion method | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11 | Novel isoquinoline derivatives as antimicrobial agents. |
| AID561100 | Antibacterial activity against Pasteurella multocida BB1034 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1001 bearing tetB gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID556349 | Antimicrobial activity against macrolide-resistant Mycoplasma pneumoniae ATCC 15531 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China. |
| AID1124945 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as growth inhibition after 16 to 20 hrs by microbroth dilution method | 2014 | Bioorganic & medicinal chemistry, Apr-01, Volume: 22, Issue:7 | Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines. |
| AID323007 | Antibacterial activity against drug-resistant Propionibacterium acnes SW101T after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1252238 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 | 2015 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 25, Issue:21 | Rapid synthesis and antimicrobial activity of novel 4-oxazolidinone heterocycles. |
| AID325009 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 427 isolate with erm(B) resistance gene from patient sinuitis by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID1551811 | Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated for 18 hrs post 30 mins pre-diffusion by disk diffusion method | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID360846 | Antibacterial activity against Streptococcus agalactiae ATCC 13813 at 30 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID556896 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 8 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1678762 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 using DMSO as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID1338317 | Antibacterial activity against Pseudomonas aeruginosa PCM 2562 after 20 hrs by microbroth dilution method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | New family of antimicrobial agents derived from 1,4-naphthoquinone. |
| AID287373 | Antibacterial activity against Klebsiella pneumoniae after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID1412157 | Bactericidal activity against Pseudomonas aeruginosa ATCC 9027 incubated for 24 hrs followed by replating on Mueller hinton agar plates and measured after 24 hrs | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID206301 | In vitro antibacterial activity against Staphylococcus aureus Smith sensitive | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID432805 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus COL at 42 degC by population analysis method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Role of a sodium-dependent symporter homologue in the thermosensitivity of beta-lactam antibiotic resistance and cell wall composition in Staphylococcus aureus. |
| AID534824 | Antimicrobial activity against ciprofloxacin-resistant Campylobacter fetus subsp. fetus 1516477 human isolate harboring tet(44) and ant(6)-Ib resistance gene in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID557210 | Antibacterial activity against Beta-lactamase-negative Neisseria meningitidis assessed as percent intermediate isolates by Etest method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. |
| AID285158 | Antimicrobial susceptibility of tetracycline-resistant Streptococcus pneumoniae from respiratory tract disease patient assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland. |
| AID600727 | Antibacterial activity against Xanthomonas oryzae at 10 ug/disc after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Urea/thiourea derivatives of quinazolinone-lysine conjugates: synthesis and structure-activity relationships of a new series of antimicrobials. |
| AID278233 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-1 gyrA+ | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID250259 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH03; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID594328 | Antimicrobial activity against Staphylococcus aureus NCIM 2079/ATCC 6538P at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID323034 | Antibacterial activity against Streptococcus dysgalactiae subsp. dysgalactiae after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID206642 | Minimum inhibitory concentration against Staphylococcus aureus | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6 | New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine. |
| AID646215 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 110 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID1056840 | Antibacterial activity against CTX-15 expressing Aeromonas caviae isolate 258 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID569302 | Antibacterial activity against Proteus vulgaris at 75 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID570782 | Antimicrobial activity against multidrug-resistant Acinetobacter baumannii assessed as resistant isolates by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania. |
| AID667265 | Antibacterial activity against Staphylococcus aureus at 1000 ug/ml after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. |
| AID585424 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G062-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID613458 | Antibacterial activity against Staphylococcus aureus NCIM 2122 after 24 hrs by NCCLS method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. |
| AID496399 | Antibacterial activity against azide-resistant Escherichia coli J53 TET2 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID1636433 | Drug activation in human Hep3B cells assessed as human CYP2D6-mediated drug metabolism-induced cytotoxicity measured as decrease in cell viability at 65.4 uM pre-incubated with BSO for 18 hrs followed by incubation with compound for 3 hrs in presence of N | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. |
| AID556649 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 4 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1079941 | Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source] | |||
| AID1442627 | Antibacterial activity against gram-negative Stenotrophomonas maltophilia SM256 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID530581 | Antimicrobial activity against macrolide-resistant Mycoplasma pneumoniae isolate 6 with A2604G mutation by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID544010 | Antimicrobial activity against Enterococcus hirae isolate PGS48 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID404899 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB34 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID295099 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 30 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID560773 | Antibacterial activity against Staphylococcus aureus TS2921 harboring ddlA Asp102Asn mutation after 20 hrs | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID569303 | Antibacterial activity against Proteus vulgaris at 100 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID56764 | Inhibition zone when tested against DAP-AT from Escherichia coli in M9-Minimal agar at concentration 30 ug | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8 | Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. |
| AID325011 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 460 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID560779 | Antibacterial activity against Staphylococcus aureus TS2921 harboring ddlA Asp102Asn mutation in fifth-instar silkworm larva infection model assessed as compound concentration per gram of larva causing reduction in survival after 48 hrs post dose at 27 de | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID1587191 | Antibacterial activity against Escherichia coli assessed as diameter of zone inhibition at 100 ppm by disc diffusion method | 2019 | European journal of medicinal chemistry, May-15, Volume: 170 | 4(3H)-Quinazolinone derivatives: Promising antibacterial drug leads. |
| AID1906418 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27883 assessed as reduction in microbial growth incubated for 24 hrs by microbroth dilution method | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Amphiphilic cyclic peptide [W |
| AID425402 | Antibacterial activity Escherichia coli isolate HM413 isolated from ileo-colonic mucosal biopsies of patient with Crohn's disease after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1311814 | Antibacterial activity against Neisseria gonorrhoeae F-18 ATCC 49226 by two fold serial dilution method | 2016 | Bioorganic & medicinal chemistry, 09-15, Volume: 24, Issue:18 | Antibacterial and anticancer activity of a series of novel peptides incorporating cyclic tetra-substituted C(α) amino acids. |
| AID535634 | Antimicrobial activity against Group B streptococcus serotype VI R6 harboring F395L, V405A, R433H, H438Y, A374V and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID484673 | Antibacterial activity against Proteus vulgaris | 2010 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 20, Issue:12 | Synthesis of novel beta-lactam fused spiroisoxazolidine chromanones and tetralones as potent antimicrobial agent for human and plant pathogens. |
| AID1617790 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated for 24 hrs by broth microdilution method | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12 | Structural Characterization and Anti-infective Activity of 9,10-Seco-29-norcycloartane Glycosides Isolated from the Flowers of the Peruvian Medicinal Plant |
| AID1159091 | Antimicrobial activity against Bacillus subtilis ATCC 6633 assessed as zone of inhibition at 30 mg by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID1678763 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27893 using cyrene as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID495516 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii AYE by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID531795 | Antibacterial activity against SCCmec type 4 genotype-positive and methicillin-resistant Staphylococcus aureus by CLSI method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. |
| AID544287 | Antimicrobial activity against Enterococcus faecalis NKH17 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1685706 | Antimicrobial activity against Escherichia coli K-12 assessed as inhibition of bacterial growth incubated for overnight by CLSI method | 2016 | Bioorganic & medicinal chemistry, 06-15, Volume: 24, Issue:12 | Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. |
| AID496398 | Antibacterial activity against azide-resistant Escherichia coli J53 TET1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID516160 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as susceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID1820917 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID447072 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID1056844 | Antibacterial activity against TEM-1/CTX-M-15 expressing Enterobacter cloacae isolate 62 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID276338 | Antimicrobial activity against Helicobacter pylori DSMZ 4867 | 2006 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 16, Issue:21 | In vitro inhibitory activity of boropinic acid against Helicobacter pylori. |
| AID368424 | Ratio of MIC for Escherichia coli KAM32 pSTVqepA mutant to MIC for Escherichia coli KAM32 pSTV28 mutant | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID1820912 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID1781496 | Anti-MDR bacterial activity against Pseudomonas aeruginosa 15690 assessed as inhibition of bacterial growth incubated for 18 hrs by microplate reader analysis | |||
| AID658534 | Antibacterial activity against Staphylococcus aureus XU212 overexpressing TetK tetracycline efflux pump after 24 hrs | 2012 | Journal of natural products, Mar-23, Volume: 75, Issue:3 | Antibacterial acylphloroglucinols from Hypericum olympicum. |
| AID460623 | Antibacterial activity against Proteus vulgaris MTCC 1771 at 50 ug/ml after 24 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID574554 | Decrease in PSMbeta1 levels in Staphylococcus aureus USA300 at subinhibitory concentration after 24 hrs by RP-HPLC/ESI-MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID1647642 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 assessed as reduction in microbial growth | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Isocadiolides A-H: Polybrominated Aromatics from a |
| AID1228687 | Antibacterial activity against tet(A) tetracycline-resistant Escherichia coli 155 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID559599 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutT mutant gene selected in presence of tobramycin by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID530429 | Resistance factor, ratio of MIC for Mycobacterium smegmatis overexpressing rv0194 gene to MIC for wild-type Mycobacterium smegmatis SMR5 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID489648 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID535635 | Antimicrobial activity against Group B streptococcus serotype VI R5 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID565329 | Antibacterial activity against Mycoplasma genitalium M6283 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID1250087 | Antibacterial activity against tolC-deficient Escherichia coli ATCC 25922 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID525125 | Suppression of drug resistance development in Staphylococcus aureus RN4220 assessed as assessed as prolonged length of subculture to develop Linezolid resistance at 0.25 times MIC | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Delayed development of linezolid resistance in Staphylococcus aureus following exposure to low levels of antimicrobial agents. |
| AID558080 | Inhibition of PAR2-mediated IL1-beta and SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes at 10 uM by ELISA | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. |
| AID572600 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium BN10055 harboring plasmid encoded RamR gene, GyrA S83Y mutant gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1688654 | Bactericidal activity against Enterococcus faecalis ATCC 29212 incubated for 24 hrs followed by transferring to freshly prepared broth medium and measured after 24 hrs by broth microdilution assay | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID444058 | Volume of distribution at steady state in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID562799 | Antimicrobial activity against Chlamydia muridarum MoPn/tetR1 harboring tet(C) allele | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID510750 | Antibacterial activity against Escherichia coli AG102MB harboring pS1328-based acrB gene | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID1228691 | Antibacterial activity against tet(A) tetracycline-resistant Enterobacter cloacae 603 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID585871 | Antimicrobial activity against Pseudomonas aeruginosa isolate 16 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID543344 | Antimicrobial activity against Aeromonas hydrophila assessed as percent tetracyclin-resistant isolate at 0.25 to >16 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID278250 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS1 acrAB::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID294966 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID535642 | Antimicrobial activity against Group B streptococcus serotype VI N4 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID569297 | Antibacterial activity against Proteus mirabilis at 50 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID559597 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutY mutant gene selected in presence of tobramycin by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID563504 | Antimicrobial activity against Serratia marcescens ATCC 13880 harboring plasmid STV29 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID1159081 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition at 30 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID424867 | Antibacterial activity against bacterial sensory kinase PhoQ deficient Salmonella enterica serovar Typhimurium CS009 by modified twofold broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance. |
| AID543365 | Antimicrobial activity against tetracycline-nonsusceptible Salmonella sp. Isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID447079 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID554650 | Antimicrobial activity against Ureaplasma urealyticum isolate HPA12 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID565058 | Antibacterial activity against wild-type Escherichia coli AG100 harboring Tn5 insertion in ycgE gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1443980 | Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate transport preincubated for 10 mins prior to ATP addition measured after 15 mins in presence of [3H]-tauroch | 2010 | Toxicological sciences : an official journal of the Society of Toxicology, Dec, Volume: 118, Issue:2 | Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. |
| AID404898 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB33 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID496819 | Antimicrobial activity against Plasmodium falciparum | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. |
| AID404897 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB30 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID535647 | Antimicrobial activity against Group B Streptococcus serotype V 2603 V/R harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID564895 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene and Tn5 insertion in ycgE gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID484675 | Antibacterial activity against Staphylococcus aureus | 2010 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 20, Issue:12 | Synthesis of novel beta-lactam fused spiroisoxazolidine chromanones and tetralones as potent antimicrobial agent for human and plant pathogens. |
| AID601193 | Clearance in Sprague-Dawley rat at 1 mg/kg, iv administered as single dose measured after 24 to 48 hrs | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID406146 | Antimicrobial activity against Escherichia coli by agar diffusion method | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi. |
| AID501853 | Antibacterial activity against Salmonella enterica ATCC 13076 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID562800 | Antimicrobial activity against Chlamydia trachomatis F/70/rifR-tetR harboring rpoB gene and tet(C) allele | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID545056 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate DL010 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID443284 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by agar dilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Anti-oxidant and anti-bacterial activities of novel N'-arylmethylidene-2-(3, 4-dimethyl-5, 5-dioxidopyrazolo[4,3-c][1,2]benzothiazin-2(4H)-yl) acetohydrazides. |
| AID554870 | Antimicrobial activity against Streptococcus pneumoniae serotype 23F ST 3250 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID587848 | Antibacterial activity against Staphylococcus aureus ATCC 13709 infected in iv dosed mouse septicemia model assessed as mouse protection after 48 hrs | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID1056836 | Antibacterial activity against CTX-15 expressing Escherichia coli isolate 235 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID294963 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID1061194 | Antimicrobial activity against Bacillus cereus MTCC 8372 at 50 ug/ml after 24 hrs by disc diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID531335 | Antibacterial activity against Pseudomonas aeruginosa TNP030 selected after 1.0 ug/ml of azithromycin by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID341060 | Activity of tetracycline efflux transporter TetA(B) Asp190Cys mutant in Escherichia coli DH5alpha membrane vesicles assessed as [3H]tetracycline uptake per mg of protein | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate. |
| AID323022 | MBC/MIC ratio of Propionibacterium acnes SW3CD | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID569306 | Antibacterial activity against Salmonella typhi at 75 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID1348085 | Antimicrobial activity against Klebsiella oxytoca ATCC 8724 assessed as zone of inhibition at 50 ug per disc after 24 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID42828 | In vitro inhibition of human recombinant IL-1-beta-induced breakdown of bovine cartilage in a cartilage organ culture assay | 1994 | Journal of medicinal chemistry, Sep-16, Volume: 37, Issue:19 | Heteroaryl-fused 2-phenylisothiazolone inhibitors of cartilage breakdown. |
| AID644028 | Antimicrobial activity against Klebsiella pneumoniae at 75 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID1158051 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 16 hrs by serial dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla. |
| AID1329753 | Antibacterial activity against Propionibacterium acnes ATCC 6919 after 24 hrs by broth microdilution method | |||
| AID565059 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID534345 | Antimicrobial activity against Burkholderia pseudomallei Bp175 harboring mini-Tn7T-P1-bpeR+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID688531 | Antibacterial activity against methicillin-resistant Staphylococcus aureus MW2 | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Antibacterial spirobisnaphthalenes from the North American cup fungus Urnula craterium. |
| AID532762 | Antimicrobial activity against Salmonella serovar Typhimurium SL1344 by broth dilution method in presence of chlorpromazine | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. |
| AID671549 | Antibacterial activity against tetracycline-resistant Staphylococcus aureus isolate SA161 expressing TetM gene | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID544011 | Antimicrobial activity against Pseudomonas borealis isolate C5 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID546620 | Antimicrobial activity against Escherichia coli harboring beta-lactamase VIM-2 by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID649515 | Antimicrobial activity against epidemic methicillin-resistant Staphylococcus aureus 16 after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry, Mar-15, Volume: 20, Issue:6 | Efficient synthesis and biological evaluation of proximicins A, B and C. |
| AID494532 | Antimicrobial activity against Bacillus subtilis NCIM 2718 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494532 | Antimicrobial activity against Bacillus subtilis NCIM 2718 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID1197614 | Inhibition of protein biosynthesis in Escherichia coli ATCC 25922 assessed as incorporation of [35S]methionine into protein at 2.5 ug/300 ul by in-vivo translation assay | 2015 | European journal of medicinal chemistry, Mar-06, Volume: 92 | Understanding the importance of glycosylated threonine and stereospecific action of Drosocin, a Proline rich antimicrobial peptide. |
| AID70927 | In vitro antibacterial activity against Escherichia coli PRP1 Tet A | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID587242 | Antimicrobial activity against Staphylococcus aureus DSM 799 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID1906414 | Antibacterial activity against Methicillin resistant Staphylococcus aureus ATCC BAA -1556 assessed as reduction in microbial growth incubated for 24 hrs by microbroth dilution method | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Amphiphilic cyclic peptide [W |
| AID285193 | Antimicrobial activity against Escherichia coli M044 mutant with AG100 lon4::IS186 marR::IS genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID524639 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing penA mutant gene assessed as incidence of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID543347 | Antimicrobial activity against Aeromonas hydrophila by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID70929 | In vitro antibacterial activity against Escherichia coli UBMS 90-4 Tet M | 1999 | Bioorganic & medicinal chemistry letters, May-17, Volume: 9, Issue:10 | Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936. |
| AID644020 | Antimicrobial activity against Staphylococcus aureus at 75 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID399617 | Antimicrobial activity against Proteus vulgaris ATCC 13315 at 0.1 mg/disk by disk diffusion assay | |||
| AID1820910 | Antibacterial activity against Staphylococcus aureus assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID508591 | Antibacterial activity against wild type Salmonella enteritidis 104 harboring gyrA D87Y mutant gene by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID544283 | Antimicrobial activity against Enterococcus faecalis NKH13 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID323913 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC G152D, D159Y, G155R and A150T mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID572811 | Antimicrobial activity against Salmonella enterica serovar Typhimurium BN18/41 harboring GyrA G81C,acrR mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID417536 | Antibacterial activity against Staphylococcus epidermidis after 24 hrs by NLCCS microdilution method | 2009 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 19, Issue:5 | Synthesis and antibacterial activity evaluation of metronidazole-triazole conjugates. |
| AID560775 | Antibacterial activity against Staphylococcus aureus TS10007 harboring ddlA Asp39Asn mutation after 20 hrs | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. |
| AID1442636 | Antibacterial activity against gram-positive Staphylococcus aureus SA161 harboring tet(M) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID545052 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ363 from patient secretion by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID56760 | Inhibition zone when tested against DAP-AT from Escherichia coli in L-agar at concentration 30 ug | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8 | Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. |
| AID609164 | Antibacterial activity against Pseudomonas antimicrobica assessed as zone of inhibition at 5 uL and 32 degC after 36 hrs by disk diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone. |
| AID554867 | Antimicrobial activity against Streptococcus pneumoniae serotype 19F ST 3245 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID1329752 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by broth microdilution method | |||
| AID360837 | Antibacterial activity against Bacillus cereus ATCC 11778 at 30 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID1131159 | Antibacterial activity against Proteus vulgaris MB838 assessed as growth inhibition at 200 ug/mL | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID285837 | Antimicrobial activity against tetracyclin-resistant Streptococcus pyogenes cMLS isolate expressing erm(B) | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID535645 | Antimicrobial activity against Group B Streptococcus serotype Ia N1 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1756235 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 assessed as bacterial growth inhibition measured after 16 hrs by serial dilution method | 2021 | Journal of natural products, 02-26, Volume: 84, Issue:2 | Hydrated Rubrolides from the New Zealand Tunicate |
| AID1159090 | Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as zone of inhibition at 30 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID1442639 | Antibacterial activity against gram-positive Streptococcus pneumoniae SP160 harboring tet(M) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID1681011 | Antibacterial activity against Bacillus subtilis assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID565331 | Antibacterial activity against Mycoplasma genitalium M6287 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID1072993 | Antibacterial activity against Porphyromonas gingivalis ATCC 33277 after 24 hrs by microbroth dilution assay | 2014 | Journal of natural products, Mar-28, Volume: 77, Issue:3 | Pyrano-isoflavans from Glycyrrhiza uralensis with antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis. |
| AID342020 | Antibacterial activity against Escherichia coli J53 by Etest | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae. |
| AID1056838 | Antibacterial activity against CTX-15 expressing Escherichia coli isolate 4024 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID1376895 | Antimicrobial activity against Staphylococcus aureus DSM 25923 assessed as growth inhibition at 7 ug per disc after 24 to 48 hrs (Rvb = 0 millimeter) | |||
| AID565010 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID565229 | Antimicrobial activity against Mycobacterium chelonae ATCC 35752 harboring pZS01 carrying mspA gene by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID1555492 | Antimycobacterial activity against Staphylococcus aureus FDA 209P by agar diffusion method | 2019 | European journal of medicinal chemistry, Aug-15, Volume: 176 | Salinomycin and its derivatives - A new class of multiple-targeted "magic bullets". |
| AID554651 | Antimicrobial activity against Ureaplasma urealyticum isolate HPA17 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID569301 | Antibacterial activity against Proteus vulgaris at 50 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID565321 | Antibacterial activity against Mycoplasma genitalium M6257 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID1338316 | Antibacterial activity against Enterococcus faecalis PCM 2673 after 20 hrs by microbroth dilution method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | New family of antimicrobial agents derived from 1,4-naphthoquinone. |
| AID279192 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolates from skin or soft tissue infection outpatients | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Treatment and outcomes of infections by methicillin-resistant Staphylococcus aureus at an ambulatory clinic. |
| AID522366 | Antimicrobial activity against wild type Proteus mirabilis N2 mutant after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID1685705 | Antimicrobial activity against Escherichia coli DH5alpha assessed as inhibition of bacterial growth incubated for overnight by CLSI method | 2016 | Bioorganic & medicinal chemistry, 06-15, Volume: 24, Issue:12 | Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. |
| AID395368 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID625281 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID428291 | Antimicrobial activity against Acinetobacter baumannii BM4652 expressing adeABC adeIJK double mutant isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID574170 | Antibacterial activity against Escherichia coli MG1655 grown as biofilms harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID632690 | Antibacterial activity against Streptococcus agalactiae after 24 to 48 hrs by microdilution method | 2011 | Journal of medicinal chemistry, Nov-24, Volume: 54, Issue:22 | Lipophosphonoxins: new modular molecular structures with significant antibacterial properties. |
| AID522655 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis BA1007 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID561747 | Antibacterial activity against Methicillin-resistant Staphylococcus aureus assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID556663 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 18 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID671548 | Antibacterial activity against tetracycline-susceptible Staphylococcus aureus ATCC 13709 Smith isolate SA100 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID1250083 | Antibacterial activity against Acinetobacter baumannii ARC 3495 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID501862 | Antifungal activity against Saccharomyces cerevisiae ATCC 9763 after 48 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID543362 | Antimicrobial activity against tetracycline-susceptible Vibrio sp. Isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID545050 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ250 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID585874 | Antimicrobial activity against Pseudomonas aeruginosa isolate 17 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID498361 | Antimicrobial activity against rifampin resistant Klebsiella pneumoniae 52deltaacrB containing isogenic acrB knockout assessed as growth inhibition by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. |
| AID1396071 | Dark toxicity against human MCF7 cells assessed as decrease in cell viability by MTT assay | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10 | Photoactivated 2,3-distyrylindoles kill multi-drug resistant bacteria. |
| AID1442625 | Antibacterial activity against gram-negative Pseudomonas aeruginosa PA169 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID562794 | Antimicrobial activity against Chlamydia trachomatis J/6276/oflR-rifR1 harboring ompA and rpoB genes | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID1269977 | Antimicrobial activity against Bacillus anthracis 34F2 Sterne after 24 hrs by double dilution method | 2015 | MedChemComm, May-01, Volume: 6, Issue:5 | Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity. |
| AID1688652 | Antifungal activity against Candida albicans ATCC 10231 assessed as reduction in bacterial growth incubated for 1 day by paper disk diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID554859 | Antimicrobial activity against Streptococcus pneumoniae serotype 14 ST 3247 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID601268 | Antimicrobial activity against tetracycline-susceptible Staphylococcus aureus Smith isolate 100 infected in po dosed mouse systemic infection model assessed as survival of mouse administered 60 mins post infection measured after 48 hrs | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID642767 | Antimicrobial activity against Bacillus subtilis at 50 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID495511 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4665 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID543346 | Antimicrobial activity against Aeromonas sobria assessed as percent tetracyclin-resistant isolate at 0.25 to >16 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID325023 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 1041 isolate with erm(B) resistance gene from patient blood by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID1159084 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as zone of inhibition at 30 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID543065 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ST398 | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Identification of a novel trimethoprim resistance gene, dfrK, in a methicillin-resistant Staphylococcus aureus ST398 strain and its physical linkage to the tetracycline resistance gene tet(L). |
| AID1685707 | Antimicrobial activity against Pseudomonas aeruginosa assessed as inhibition of bacterial growth incubated for overnight by CLSI method | 2016 | Bioorganic & medicinal chemistry, 06-15, Volume: 24, Issue:12 | Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. |
| AID559594 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutM mutant gene selected in presence of Ceftazidime by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID1654444 | Antibacterial activity against Staphylococcus aureus INCAS0039 assessed as reduction in microbial growth by CLSI based broth microdilution method | 2020 | Journal of natural products, 03-27, Volume: 83, Issue:3 | Meliponamycins: Antimicrobials from Stingless Bee-Associated |
| AID396269 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(E) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID530350 | Antimicrobial activity against Escherichia coli TOP10 by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID585420 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W191-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID574551 | Decrease in delta toxin levels in Staphylococcus aureus Sanger 252 at subinhibitory concentrations after 24 hrs by RP-HPLC/ESI- MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID294964 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID323000 | Antibacterial activity against drug-resistant Propionibacterium acnes SW3CD after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID530760 | Induction of PsgtB::lacZ gene expression in Staphylococcus aureus SH1000 at 2 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID572813 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium BN18/41 harboring plasmid encoded RamR gene, GyrA G81C,acrR mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID556887 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 27 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID602693 | Binding affinity to bone mineral hydroxyapatite assessed as binding index after 24 hrs by UV-spectrophotometer analysis relative to 5-fluorouracil | 2011 | Bioorganic & medicinal chemistry, Jun-15, Volume: 19, Issue:12 | Selective bone targeting 5-fluorouracil prodrugs: synthesis and preliminary biological evaluation. |
| AID565013 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID646236 | AUClast in Sprague-Dawley rat at 1 mg/kg, iv by LC/MS-MS analysis | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID563507 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 71 harboring plasmid STV29 expressing hasF gene by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID1617935 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as bacterial growth inhibition measured after 48 hrs by resazurin assay | |||
| AID447073 | Antibacterial activity against Klebsiella pneumoniae UC57 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID1325498 | Antibacterial activity against gentamicin-resistant Staphylococcus aureus NRS-108 | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: Modifications at C-12. |
| AID613457 | Antibacterial activity against Escherichia coli NCIM 2574 after 24 hrs by NCCLS method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. |
| AID572816 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium BN18/71 harboring plasmid encoded RamR gene, GyrA G81C,acrR mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID278675 | Antibacterial activity against Enterococcus faecalis isolate 5743 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID544281 | Antimicrobial activity against Enterococcus faecalis NKH11 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID454164 | Antimicrobial activity against Staphylococcus aureus MTCC 96 at 10 ug/ml after 24 hrs by agar diffusion method | 2009 | Bioorganic & medicinal chemistry, Dec-15, Volume: 17, Issue:24 | Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents. |
| AID534404 | Antibacterial activity against Escherichia coli EPI300 expressing tet(40) gene assessed as inhibition of bacterial growth at 80 ug/ml after 18 hrs in presence of 2.5 ug/ml efflux pump inhibitor CCP | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones. |
| AID1465955 | Antibacterial activity against Bacillus cereus after 20 hrs by broth microdilution method | 2017 | Bioorganic & medicinal chemistry, 06-01, Volume: 25, Issue:11 | Metabolite diversification by cultivation of the endophytic fungus Dothideomycete sp. in halogen containing media: Cultivation of terrestrial fungus in seawater. |
| AID278260 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS14 with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID522645 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis Texas by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID278253 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS3 gyrA+ with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID525143 | Antimicrobial activity against linezolid-resistant Staphylococcus aureus isolate 004-737X expressing cfr and ermA gene isolated from paraplegic patient by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States. |
| AID559356 | Antimicrobial activity against Salmonella spp. harboring tetB gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID341055 | Antibacterial activity against intact Escherichia coli DH5alpha expressing wild-type tetracycline efflux transporter TetA(B) gene | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate. |
| AID388002 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by microdilution broth method | 2008 | Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22 | Structure-activity relationship of antibacterial chalcones. |
| AID467962 | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID1056843 | Antibacterial activity against CTX-15 expressing Enterobacter cloacae isolate 51 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID495512 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4666 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID671557 | Antibacterial activity against Staphylococcus aureus ATCC 13709 infected in CD-1 mouse assessed as increase in survival at 30 mg/kg, po administered as single dose 1 hr post infection measured after 48 hrs post infection | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID423151 | Antibacterial activity against Bifidobacterium thermophilum B0219 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Mosaic tetracycline resistance genes and their flanking regions in Bifidobacterium thermophilum and Lactobacillus johnsonii. |
| AID625277 | FDA Liver Toxicity Knowledge Base Benchmark Dataset (LTKB-BD) drugs of less concern for DILI | 2011 | Drug discovery today, Aug, Volume: 16, Issue:15-16 | FDA-approved drug labeling for the study of drug-induced liver injury. |
| AID564893 | Antibacterial activity against wild-type Escherichia coli AG100 harboring marR mutant gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1678768 | Antibacterial activity against Staphylococcus aureus ATCC 43300 using Cyrene as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID315450 | Antibacterial activity against Streptococcus pneumoniae by micro-broth dilution assay | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of 3-arylamino-1-chloropropan-2-ols. |
| AID278238 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-2 acrAB::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID323908 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC G152D and D159Y mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID1442631 | Antibacterial activity against gram-negative Klebsiella pneumoniae KP457 harboring blacTX-M-15 extended spectrum beta-lactamase gene by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID322257 | Antibacterial activity against Proteus mirabilis by well diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 18, Issue:7 | Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens. |
| AID509867 | Antibacterial activity against Acinetobacter baumannii isolate 2824 isolated from human urine | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID563512 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens 011 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID1158048 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as compound level causing less than 2% growth after 16 hrs by serial dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla. |
| AID1225259 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 assessed as bacterial growth inhibition after 24 hrs by standard broth microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 25, Issue:1 | A potent antimicrobial compound isolated from Clathria cervicornis. |
| AID573966 | Antibacterial activity against Cj1211-positive Campylobacter jejuni harboring aphA3 and tet(O) genes | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of Cj1211 in natural transformation and transfer of antibiotic resistance determinants in Campylobacter jejuni. |
| AID278579 | Decrease in Plasmodium falciparum FCK2 in erythrocytes at 50 uM after 84 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID644027 | Antimicrobial activity against Klebsiella pneumoniae at 50 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID559355 | Antimicrobial activity against Salmonella spp. harboring tetA gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID1339206 | Inhibition of MMP2 in inflamed tissue isolated from chronic periodontitis patient at 500 ug/l after 15 to 30 mins by gelatin zymographic method relative to control | 2017 | Bioorganic & medicinal chemistry, 02-15, Volume: 25, Issue:4 | 3,4-Dihydropyrimidinone-coumarin analogues as a new class of selective agent against S. aureus: Synthesis, biological evaluation and molecular modelling study. |
| AID283156 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2394 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID554673 | Antimicrobial activity against Streptococcus pneumoniae serotype 9V ST 156 harboring ERY-resistant erm(B) or mef(E) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID260687 | Antibacterial activity against Xanthomonas campestris pvs by disk diffusion method at 10 ug/disk | 2006 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 16, Issue:4 | Microwave-assisted synthesis of N-alkylated benzotriazole derivatives: antimicrobial studies. |
| AID601192 | AUC (0 to infinity) in Sprague-Dawley rat at 1 mg/kg, iv administered as single dose measured after 24 to 48 hrs | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID540826 | Antimicrobial activity against ramA::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 5408-cip harboring gyrA D87Y, gyrB E466D, parE V461G mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID278235 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-1 tolC::Kan with GyrA S83F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1252239 | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 | 2015 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 25, Issue:21 | Rapid synthesis and antimicrobial activity of novel 4-oxazolidinone heterocycles. |
| AID1131162 | Antibacterial activity against Staphylococcus aureus MB108 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID41090 | Evaluated for the in vitro minimum bactericidal concentration (MBC) against periopathogenic Bacteroides gingivalis bacteria | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1 | Substituted 2-(2-hydroxyphenyl)benzimidazoles as potential agents for the control of periodontal diseases. |
| AID649518 | Antimicrobial activity against Enterococcus faecalis NCTC 12697 after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry, Mar-15, Volume: 20, Issue:6 | Efficient synthesis and biological evaluation of proximicins A, B and C. |
| AID295108 | Antibacterial activity against Proteus vulgaris ATCC 8427 at 30 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID325028 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 326 isolate with erm(B) resistance gene from patient blood by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID341107 | Antibacterial activity against Escherichia coli transconjugant carrying pEC28 isolate eby Etest | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | First occurrence of an Escherichia coli clinical isolate producing the VIM-1/VIM-2 hybrid metallo-beta-lactamase VIM-12. |
| AID388086 | Antibacterial activity at Escherichia coli | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents. |
| AID584121 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ST398 isolate 11 containing apmA, erm(B), tet(L), tet(M), tet(K), dfrK, aadD, mecA, blaZ resistance genes by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID1338318 | Antibacterial activity against Klebsiella pneumoniae PCM1 after 20 hrs by microbroth dilution method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | New family of antimicrobial agents derived from 1,4-naphthoquinone. |
| AID646206 | Antibacterial activity against Staphylococcus aureus ATCC 101 29213 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID1424150 | Antibacterial activity against Pseudomonas aeruginosa by broth dilution assay | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Antibacterial Compounds from Marine Bacteria, 2010-2015. |
| AID559357 | Antimicrobial activity against Salmonella spp. harboring tetG gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID548256 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID312016 | Antifungal activity against Botrytis cinerea at 10 ug/disc after 48 hrs by disc diffusion assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae. |
| AID1335603 | Antibacterial activity against Escherichia coli ATCC 10535 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID559803 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutT mutant gene selected in presence of ciprofloxacin by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID285203 | Antimicrobial activity against Escherichia coli M124 mutant with AG100 lon4::IS186 acrR::IS genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID588209 | Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset | 2010 | Chemical research in toxicology, Jul-19, Volume: 23, Issue:7 | Developing structure-activity relationships for the prediction of hepatotoxicity. |
| AID586086 | Antimicrobial activity against verocytotoxin-producing Escherichia coli isolate O157 obtained from animals and food assessed as percentage of resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID543353 | Antimicrobial activity against Salmonella serogroup O8 assessed as percent tetracyclin-resistant isolate at 1 to >128 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID307123 | Antimycobacterial activity against Mycobacterium tuberculosis by agar dilution method | 2007 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 17, Issue:8 | Newer tetracycline derivatives: synthesis, anti-HIV, antimycobacterial activities and inhibition of HIV-1 integrase. |
| AID1056837 | Antibacterial activity against TEM-1/SHV-12 expressing Escherichia coli isolate 237 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID322993 | Antibacterial activity against drug-resistant Propionibacterium acnes D-04/97 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID322256 | Antibacterial activity against Proteus vulgaris by well diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 18, Issue:7 | Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens. |
| AID718415 | Antibacterial activity against log-phase methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as growth inhibition after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. |
| AID1339205 | Inhibition of MMP9 in inflamed tissue isolated from chronic periodontitis patient at 500 ug/l after 15 to 30 mins by gelatin zymographic method relative to control | 2017 | Bioorganic & medicinal chemistry, 02-15, Volume: 25, Issue:4 | 3,4-Dihydropyrimidinone-coumarin analogues as a new class of selective agent against S. aureus: Synthesis, biological evaluation and molecular modelling study. |
| AID584822 | Effect on Pseudomonas putida PAW340 biofilms assessed as heat production at 250 ug/ml by Chip calorimetry | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Chip calorimetry for fast and reliable evaluation of bactericidal and bacteriostatic treatments of biofilms. |
| AID585419 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W281-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1630578 | Antibacterial activity against Staphylococcus aureus SG 511 after 24 hrs by two fold serial dilution method | 2016 | Bioorganic & medicinal chemistry letters, 10-15, Volume: 26, Issue:20 | Synthesis and antibacterial evaluation of hamacanthin B analogues. |
| AID1585461 | Antibacterial activity against erythromycin-resistant Staphylococcus aureus NRS-70 measured after 16 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents. |
| AID285200 | Antimicrobial activity against Escherichia coli M103 mutant with AG100 lon3::IS186 acrR-acrAB genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID592501 | Antifungal activity against Microbotryum violaceum assessed as zone of inhibition measured as radius at 50 ug by agar diffusion assay | 2011 | Journal of natural products, Mar-25, Volume: 74, Issue:3 | Diversonol and blennolide derivatives from the endophytic fungus Microdiplodia sp.: absolute configuration of diversonol. |
| AID565436 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 biofilm assessed as biofilm bacterial count at 0.05 ug/ml (Rvb =402.9 +/- 26.88 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID372897 | Antibacterial activity against Streptococcus faecalis ATCC 9790 after 24 hrs by MTT assay | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. |
| AID530586 | Antimicrobial activity against macrolide-resistant Mycoplasma pneumoniae isolate 685 with A2603G mutation by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID1335599 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID532573 | Antimicrobial activity against Salmonella serovar Typhimurium SL1344 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. |
| AID557077 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes ATCC 15038 harboring pDrive plasmid expressing ampC gene by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID323008 | Antibacterial activity against drug-resistant Propionibacterium acnes GE46EB after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID524824 | Antibacterial activity against erythromycin resistant Campylobacter sp. by agar plate dilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID404949 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate assessed as percent resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID1442638 | Antibacterial activity against gram-positive Enterococcus faecalis EF159 harboring tet(M) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID1678765 | Antibacterial activity against Escherichia coli ATCC 25922 using cyrene as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID362544 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 25923 after 18 hrs | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. |
| AID322995 | Antibacterial activity against drug-resistant Propionibacterium acnes EG7NS after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID544024 | Antimicrobial activity against Acinetobacter calcoaceticus isolate C35 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1726821 | Antibacterial activity against Escherichia coli MTCC 1687 incubated for 14 to 16 hrs by micro broth dilution method | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6 | Sulfonium-based liposome-encapsulated antibiotics deliver a synergistic antibacterial activity. |
| AID362543 | Antibacterial activity against tetracycline-resistant Staphylococcus aureus XU212 after 18 hrs | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. |
| AID322258 | Antibacterial activity against Staphylococcus aureus by well diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 18, Issue:7 | Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens. |
| AID629281 | Antibacterial activity against Photobacterium leiognathi Sh1 assessed as inhibition of bacterial luminescence at 0.025 mg/mL after 10 mins by bioluminometry-based chronic action test | 2011 | European journal of medicinal chemistry, Dec, Volume: 46, Issue:12 | Synthesis and biological activity of novel N-cycloalkyl-(cycloalkylaryl)-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-yl)thio]acetamides. |
| AID283555 | Antimicrobial activity against Streptococcus pneumoniae R6 transformants | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID543359 | Antimicrobial activity against Salmonella serogroup O9 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID360841 | Antibacterial activity against Staphylococcus aureus ATCC 27853 at 30 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID1124946 | Antibacterial activity against methicillin-resistant Staphylococcus aureus subsp. aureus ATCC 43300 assessed as growth inhibition after 16 to 20 hrs by microbroth dilution method | 2014 | Bioorganic & medicinal chemistry, Apr-01, Volume: 22, Issue:7 | Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines. |
| AID556875 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 15 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1577573 | Antibacterial activity against Escherichia coli assessed as inhibition of bacterial growth after 24 hrs by microdilution method | |||
| AID1079940 | Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source] | |||
| AID1231525 | Antibacterial activity against Enterococcus faecalis CECT 481 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter broth dilution method | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antibacterial activities of cadiolides A, B and C and analogues. |
| AID509870 | Antibacterial activity against Acinetobacter baumannii isolate 5191 isolated from human urine | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID1689766 | Antibacterial activity against Enterococcus faecalis ATCC 29212 | 2020 | European journal of medicinal chemistry, Mar-01, Volume: 189 | Simple amphiphilic α-hydrazido acids: Rational design, synthesis, and in vitro bioactivity profile of a novel class of potential antimicrobial compounds. |
| AID369661 | Antibacterial activity against Campylobacter jejuni 81-176 cmeB: kanamycin-resistant mutant carrying tet(O)+ gene | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID278257 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS9 gyrA+ with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1159088 | Antimicrobial activity against Proteus vulgaris ATCC 33420 assessed as zone of inhibition at 30 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID534825 | Antimicrobial activity against Campylobacter fetus subsp. fetus CA73 harboring pCA73 carrying tet(44) resistance gene of 1516477 in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID1848325 | Antibacterial activity against Porphyromonas gingivalis ATCC 33277 assessed as growth inhibition at 2.81 uM measured after 24 hrs by WST-1 assay relative to control | |||
| AID529885 | Antibacterial activity against Staphylococcus aureus RN4220 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID368421 | Antimicrobial activity against Escherichia coli KAM32 pSTV28 containing chloramphenicol-resistant vector by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID574544 | Activity of Quorum sensing agr in community-associated methicillin-resistant Staphylococcus aureus USA300 assessed as PSMbeta expression after 8 hrs by qRT-PCR | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID250267 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH20; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID520704 | Antibacterial activity against tetracycline resistant Streptococcus pneumoniae clinical isolate expressing erm(B) and tet(M) gene by agar dilution CLSI method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | erm(B)-carrying elements in tetracycline-resistant pneumococci and correspondence between Tn1545 and Tn6003. |
| AID338052 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 16 hrs by microdilution assay | |||
| AID554877 | Antimicrobial activity against Streptococcus pneumoniae serotype 6B ST 138 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID545044 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ078 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID1056841 | Antibacterial activity against TEM-1/SHV-12 expressing Aeromonas hydrophila isolate 268 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID278264 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS18 with GyrA S38F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID278679 | Antibacterial activity against Enterococcus faecium isolate 5750 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID1678761 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 using cyrene as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID1131164 | Antibacterial activity against Bacillus subtilis MB964 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID565319 | Antibacterial activity against Mycoplasma genitalium M2321 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID404896 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB28 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID535644 | Antimicrobial activity against Group B streptococcus serotype Ib N2 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID530288 | Antimicrobial activity against PR-39-resistant Salmonella enterica serovar Typhimurium LT2 DA6192 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID477099 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 2488 at 10 ug/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives. |
| AID530580 | Antimicrobial activity against Mycoplasma pneumoniae isolate FH by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID556687 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 14 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID571884 | Antibacterial activity against Escherichia coli KAM32 harboring recombinant plasmid pVBS1 encoding Acinetobacter baumannii abeS gene by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii. |
| AID646211 | Antibacterial activity against Streptococcus pneumoniae ATCC 106 49619 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID680162 | TP_TRANSPORTER: uptake in OAT4-expressing S2 cells | 2002 | Japanese journal of pharmacology, Jan, Volume: 88, Issue:1 | Human organic anion transporters mediate the transport of tetracycline. |
| AID369668 | Antibacterial activity against Campylobacter jejuni 23-51 cme:: Kanamycin-resistant mutant assessed by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID428274 | Antimicrobial activity against carbapenemase producing Enterobacter sp. assessed as resistant isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID1159083 | Antimicrobial activity against Micrococcus luteus ATCC 9341 assessed as zone of inhibition at 30 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID532025 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H assessed as 2-fold increase in reserpine-mediated inhibition of bacterial growth after 14 days | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID524663 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing mtrR mutant gene assessed as percentage intermediate isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID1131167 | Antibacterial activity against Klebsiella aerogenes MB1503 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID556667 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 22 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID562473 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 transconjugant expressing beta-lactamase KPC-2/TEM-1 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID360363 | Antimalarial activity after 96 hrs against Plasmodium falciparum Dd2 by [3H]hypoxanthine uptake | 2007 | The Journal of biological chemistry, Jan-26, Volume: 282, Issue:4 | In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. |
| AID283157 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2414 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID489647 | Antibacterial activity against Enterobacter cloacae ATCC 49141 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID307414 | Antibacterial activity against Pseudomonas aeruginosa ATCC 11775 | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Syntheses and antibacterial activity of phendioxy substituted cyclic enediynes. |
| AID323914 | Antibacterial activity against Staphylococcus aureus 2A1-1 with rplC G152D, D159Y and unmapped mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID323023 | MBC/MIC ratio of Propionibacterium acnes P95 | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID283166 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL5204 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID56761 | Inhibition zone when tested against DAP-AT from Escherichia coli in L-agar at concentration 300 ug | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8 | Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. |
| AID585425 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G375-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1634992 | Antimicrobial activity against Staphylococcus aureus clinical isolates from university hospital in Motol assessed as reduction in bacterial growth after 20 hrs by drop diffusion test | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID1335601 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID572788 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium 543SA98 harboring plasmid encoded RamR gene, GyrA S83Y mutant gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID543349 | Antimicrobial activity against Aeromonas sobria by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID556666 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 21 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID544273 | Antimicrobial activity against Enterococcus faecalis NKH3 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID561740 | Antibacterial activity against Beta-hemolytic Streptococcus group A assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID660265 | Antimicrobial activity against wild type Escherichia coli expressing AcrAB-TolC efflux pump | 2012 | European journal of medicinal chemistry, Jun, Volume: 52 | Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. |
| AID532678 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as resistant isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID565067 | Antibacterial activity against CTX-M-15 and SHV-27 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID585863 | Antimicrobial activity against Pseudomonas aeruginosa isolate 12 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1240015 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 50 ug/ml after 24 hrs by disc diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID444052 | Hepatic clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID565445 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.07 ug/ml (Rvb =310.8 +/- 17.10 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID678719 | Metabolic stability in human liver microsomes assessed as medium signal/noise ratio (S/N of 10 to 100) by measuring GSH adduct formation at 100 uM after 90 mins by HPLC-MS analysis | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID283164 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2640 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID1689767 | Antibacterial activity against Staphylococcus aureus ATCC 29213 | 2020 | European journal of medicinal chemistry, Mar-01, Volume: 189 | Simple amphiphilic α-hydrazido acids: Rational design, synthesis, and in vitro bioactivity profile of a novel class of potential antimicrobial compounds. |
| AID87950 | Minimum inhibitory concentration against Helicobacter pylori (Helicobacter pylori) ARHp strain 115 | 2002 | Journal of medicinal chemistry, Sep-12, Volume: 45, Issue:19 | Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 2. |
| AID561755 | Antibacterial activity against Methicillin-sensitive Staphylococcus aureus assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID562813 | Antimicrobial activity against Escherichia coli DH5[alpha] harboring pEK516 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID1698042 | Antibacterial activity against Pseudomonas aeruginosa assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID560222 | Antibacterial activity against Salmonella enterica serovar Typhimurium 01-4 by CLSI M7-A7 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Outer membrane protein STM3031 (Ail/OmpX-like protein) plays a key role in the ceftriaxone resistance of Salmonella enterica serovar Typhimurium. |
| AID529897 | Antimicrobial activity against Leptospira interrogans serovar Pyrogenes isolate 5 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID636840 | Antibacterial activity against Pseudomonas aeruginosa at 1 to 10 mg/mL after 24 hrs by agar well diffusion method | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1 | Efficient one-pot preparation of novel fused chromeno[2,3-d]pyrimidine and pyrano[2,3-d]pyrimidine derivatives. |
| AID667270 | Antibacterial activity against Escherichia coli at 500 ug/ml after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. |
| AID508595 | Antibacterial activity against wild type Salmonella enteritidis 5408 harboring gyrA D87Y mutant gene by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID575946 | Antimicrobial activity against erythromycin-resistant Streptococcus pneumoniae assessed as susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates. |
| AID283550 | Antimicrobial activity against Streptococcus pneumoniae BSF-11524 isolate with erm(B) and L4 mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID562795 | Antimicrobial activity against Chlamydia muridarum MoPn/oflR-rifR harboring ompA and rpoB genes | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID540932 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor SP2 harboring rpsL K88E mutant gene and inserted glycine at position 92 of the gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID525040 | Antimicrobial activity against fluoroquinolone-susceptible Escherichia coli PS5 harboring GyrA S83L mutant gene by Etest | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Constitutive SoxS expression in a fluoroquinolone-resistant strain with a truncated SoxR protein and identification of a new member of the marA-soxS-rob regulon, mdtG. |
| AID559600 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 selected in presence of ciprofloxacin by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID1376891 | Antimicrobial activity against Escherichia coli DSM 8579 assessed as growth inhibition at 7 ug per disc after 24 to 48 hrs (Rvb = 0 millimeter) | |||
| AID362542 | Antibacterial activity against macrolide-resistant Staphylococcus aureus RN4220 after 18 hrs | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. |
| AID544275 | Antimicrobial activity against Enterococcus faecalis NKH5 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID523002 | Cytotoxicity against human 5637 cells assessed as mild induction of cell death by LDH release assay | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID1689768 | Antibacterial activity against Escherichia coli ATCC 25922 | 2020 | European journal of medicinal chemistry, Mar-01, Volume: 189 | Simple amphiphilic α-hydrazido acids: Rational design, synthesis, and in vitro bioactivity profile of a novel class of potential antimicrobial compounds. |
| AID404947 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate assessed as percent resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID613193 | Antibacterial activity against Haemophilus influenzae ATCC 10211 after 24 hrs by MTT assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives. |
| AID667271 | Antibacterial activity against Escherichia coli at 1000 ug/ml after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. |
| AID530051 | Antimicrobial activity against Staphylococcus aureus 286607-R1 harboring wild type gyrB by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID323003 | Antibacterial activity against drug-resistant Propionibacterium acnes P425:1 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID27797 | Maximum plasma concentration (Cmax) after oral dosing by gavage needle at 30 mg/kg in C57BL/6NTac female mice; Not checked | 2002 | Journal of medicinal chemistry, Sep-12, Volume: 45, Issue:19 | Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 2. |
| AID324168 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 at 25 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID312013 | Antibacterial activity against Escherichia coli at 10 ug/disc after 48 hrs by disc diffusion assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae. |
| AID323013 | Antibacterial activity against drug-resistant Propionibacterium acnes P:413 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1335597 | Antibacterial activity against Bacillus pumilus NCTC 8241 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID396275 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(B), tet(C) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID540212 | Mean residence time in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID556902 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 14 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID575170 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 200 uM by spectrofluorometric assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID460803 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BAA-1605 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID525144 | Antimicrobial activity against Staphylococcus epidermidis isolate 426-3147L expressing cfr gene by broth microdilution CLSI method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States. |
| AID285838 | Antimicrobial activity against tetracycline-susceptible Streptococcus pyogenes cMLS isolate expressing erm(B) | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID516163 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as resistant isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID559345 | Antimicrobial activity against Shigella sonnei harboring tetG gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID460624 | Antibacterial activity against Klebsiella pneumoniae NCIM 2957 at 50 ug/ml after 24 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID495514 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4668 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID582764 | Antimicrobial activity against eaeA negative verocytotoxin-producing non-O157 Escherichia coli isolates obtained from human assessed as percentage of resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID285190 | Antimicrobial activity against Escherichia coli AG100 mutant with argE3 thi-3 rpsL xyl mtl supE44 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID325445 | Antibacterial activity against Escherichia coli C921-61 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID556662 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 17 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565453 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.07 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =413.7 +/- 24.47 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID540865 | Antimicrobial activity against Salmonella enterica serovar enteritidis isolate 104-cip harboring gyrA D87Y,S83F mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID559595 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutT mutant gene selected in presence of Ceftazidime by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID588120 | Antimicrobial activity against Streptococcus suis CA isolated from cerebrospinal fluid of patient with meningitis by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Feb, Volume: 55, Issue:2 | Different genetic elements carrying the tet(W) gene in two human clinical isolates of Streptococcus suis. |
| AID278678 | Antibacterial activity against Enterococcus faecium isolate 5749 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID561107 | Antibacterial activity against Pasteurella multocida BB1041 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID548471 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID574552 | Decrease in delta toxin levels in Staphylococcus aureus USA300 at subinhibitory concentrations after 24 hrs by RP-HPLC/ESI- MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID544278 | Antimicrobial activity against Enterococcus faecalis NKH8 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID562798 | Antimicrobial activity against Chlamydia muridarum MoPn/tetR14 harboring tet(C) allele | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID584123 | Antimicrobial activity against Staphylococcus aureus RN4220 carrying pAFS11-apmA, erm(B), tet(L), dfrK, aadD resistance genes by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID368420 | Antimicrobial activity against Escherichia coli KAM32 pHPA containing mutated GyrA gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID680185 | TP_TRANSPORTER: inhibition of E1S uptake (E1S: 0.05 uM, Tetracycline: 50 uM) in OAT4-expressing S2 cells | 2002 | Japanese journal of pharmacology, Jan, Volume: 88, Issue:1 | Human organic anion transporters mediate the transport of tetracycline. |
| AID556890 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 2 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID557799 | Antimicrobial activity against Escherichia coli J53 by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID1820916 | Antibacterial activity against Acinetobacter baumannii assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID424866 | Antibacterial activity against wild type Salmonella enterica serovar Typhimurium ATCC 14028 by modified twofold broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance. |
| AID678447 | Antibacterial activity against Pseudomonas aeruginosa at 12 ug/well after 24 hrs by agar well diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. |
| AID609165 | Antibacterial activity against Staphylococcus equorum assessed as zone of inhibition at 5 uL and 32 degC after 36 hrs at by disk diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone. |
| AID1473741 | Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 20 mins by membrane vesicle transport assay | 2013 | Toxicological sciences : an official journal of the Society of Toxicology, Nov, Volume: 136, Issue:1 | A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. |
| AID1731000 | Antibacterial activity against Escherichia coli AB1157 assessed as inhibition of bacterial growth measured after 18 hrs by two fold serial dilution method | 2021 | European journal of medicinal chemistry, Mar-05, Volume: 213 | Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules. |
| AID565326 | Antibacterial activity against Mycoplasma genitalium M6090 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID532677 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as intermediate resistant isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID285192 | Antimicrobial activity against Escherichia coli M043 mutant with AG100 lon4::IS186 marR::IS2 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID1127615 | Antibacterial activity against wild type Streptococcus pneumoniae assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID522651 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis K5926 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID285849 | Antimicrobial activity against tetracyclin-resistant Streptococcus pyogenes C-105 transconjugated with erm(B) and tet(M) genes | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID1131172 | Antibacterial activity against Corynebacterium pseudodiphtheriticum assessed as growth inhibition at 2 to 8 ug/mL | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID1079943 | Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] | |||
| AID564892 | Antibacterial activity against ompF-deficient Escherichia coli AG100 at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID348884 | Antibacterial activity against Bacillus pumilus PTCC 1114 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID278676 | Antibacterial activity against Enterococcus faecalis isolate 5742 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID1442630 | Antibacterial activity against gram-positive Enterococcus faecium EFm404 harboring tet(M) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID322989 | Antibacterial activity against drug-resistant Propionibacterium acnes SW10 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID495753 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow and treated with Cefixime-cluvulanic acid by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID1442623 | Antibacterial activity against gram-negative Klebsiella pneumoniae KP194 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID1392011 | Antistaphylococcal activity against erythromycin-resistant Staphylococcus aureus NRS-70 after 18 hrs by two-fold serial dilution method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10 | The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid. |
| AID307118 | Antiviral activity against HIV1 3B in CEM cells assessed as inhibition of viral-induced cytopathicity | 2007 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 17, Issue:8 | Newer tetracycline derivatives: synthesis, anti-HIV, antimycobacterial activities and inhibition of HIV-1 integrase. |
| AID1228681 | Antibacterial activity against methicillin-resistant, tet(M) tetracycline-resistant Staphylococcus aureus 161 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID285199 | Antimicrobial activity against Escherichia coli M093 mutant with AG100 lon3::IS186 acrR::IS1 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID562797 | Antimicrobial activity against Chlamydia trachomatis L2/tetR1 harboring tet(C) allele | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID1287895 | Antimicrobial activity against Escherichia coli after 24 hrs by serial dilution method | 2016 | European journal of medicinal chemistry, May-04, Volume: 113 | Synthetic approaches, structure activity relationship and biological applications for pharmacologically attractive pyrazole/pyrazoline-thiazolidine-based hybrids. |
| AID1056835 | Antibacterial activity against SIM-1 expressing Acinetobacter baumannii isolate 170 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID1551779 | Antibacterial activity against Bacillus subtilis assessed as zone of inhibition | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID534406 | Antibacterial activity against Escherichia coli EPI300 expressing tet(W) gene assessed as inhibition of bacterial growth at 60 ug/ml after 18 hrs in presence of 2.5 ug/ml efflux pump inhibitor CCCP | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones. |
| AID558077 | Inhibition of PAR2-mediated SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes at 5 uM after 24 hrs by ELISA | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. |
| AID564894 | Antibacterial activity against wild-type Escherichia coli AG100 harboring marR mutant gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1067612 | Antiprion activity at scrapie prion protein in human brain at 1 mM after 1 hr by Western blotting analysis | 2013 | Journal of medicinal chemistry, Aug-08, Volume: 56, Issue:15 | A new face for old antibiotics: tetracyclines in treatment of amyloidoses. |
| AID525041 | Antimicrobial activity against fluoroquinolone-resistant Escherichia coli NorE5 harboring GyrA S83L mutant, ParC S80R mutant, truncated SoxR and constitutively active SoxS by Etest | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Constitutive SoxS expression in a fluoroquinolone-resistant strain with a truncated SoxR protein and identification of a new member of the marA-soxS-rob regulon, mdtG. |
| AID565071 | Antibacterial activity against CTX-M-15 ESBL producing Klebsiella pneumoniae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID396496 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(A), tet(B), tet(D) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID565317 | Antibacterial activity against Mycoplasma genitalium M2282 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID625289 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1347489 | Antibacterial activity against Serratia marcescens assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID404901 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB41 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID325482 | Antibacterial activity against Escherichia coli W4573 assessed as inhibition of AcrAB efflux pump after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID565325 | Antibacterial activity against Mycoplasma genitalium M6328 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID425404 | Antibacterial activity against Escherichia coli isolate HM95 isolated from ileal mucosal biopsies of patient with Crohn's disease after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1061192 | Antimicrobial activity against Staphylococcus aureus MTCC 96 at 50 ug/ml after 24 hrs by disc diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID447077 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID569300 | Antibacterial activity against Proteus vulgaris at 25 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID369229 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae assessed as percent resistant isolates by CLSI breakpoint method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID283658 | Antimicrobial activity against Haemophilus influenzae NB65044 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number. |
| AID683715 | Antimalarial activity against Plasmodium vivax assessed as effect on cure rate after 28 days | 2012 | Journal of medicinal chemistry, Feb-09, Volume: 55, Issue:3 | Targeting the liver stage of malaria parasites: a yet unmet goal. |
| AID565066 | Antibacterial activity against CTX-M-15 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID1688653 | Antifungal activity against Aspergillus brasiliensis ATCC 16404 assessed as reduction in bacterial growth incubated for 3 days by paper disk diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID1577574 | Antibacterial activity against Staphylococcus aureus assessed as inhibition of bacterial growth after 24 hrs by microdilution method | |||
| AID1698041 | Antibacterial activity against Salmonella typhi assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID562793 | Antimicrobial activity against Chlamydia trachomatis L2/oflR-rifR2 harboring ampA and rpoB genes | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID534826 | Antimicrobial activity against kanamycin-resistant Campylobacter fetus subsp. fetus CA74 harboring deletion in tet(44)::pCA64 resistant gene in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID572150 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBAD plasmid after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID460802 | Antibacterial activity against Acinetobacter baumannii AB0043 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID524674 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ and mtrR mutant gene assessed as percentage intermediate isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID560248 | Antibacterial activity against Staphylococcus aureus RN4220 harboring aadD, tet(L), dfrK and vga(C) gene by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID353043 | Antimicrobial activity against Proteus vulgaris at 100 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID475504 | Binding affinity to amyloid beta (1 to 42) fibrils by change in fluorescence at 100 uM after 10 mins | 2009 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 19, Issue:17 | A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta. |
| AID1299634 | Antibiofilm activity against Pseudomonas aeruginosa PAO1 ATCC 47085 after 24 hrs by crystal violet staining-based spectrophotometry | 2016 | Journal of medicinal chemistry, Apr-14, Volume: 59, Issue:7 | Antibacterial Diamines Targeting Bacterial Membranes. |
| AID572790 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium BN9945 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID559326 | Antimicrobial activity against Shigella sonnei assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID494534 | Antimicrobial activity against Pseudomonas aeruginosa NCIM 5029 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494534 | Antimicrobial activity against Pseudomonas aeruginosa NCIM 5029 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID667400 | Antibacterial activity against Bacillus subtilis at 1000 ug/ml after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. |
| AID311524 | Oral bioavailability in human | 2007 | Bioorganic & medicinal chemistry, Dec-15, Volume: 15, Issue:24 | Hologram QSAR model for the prediction of human oral bioavailability. |
| AID544023 | Antimicrobial activity against Psychrobacter ikaite isolate C713 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID556694 | Antimicrobial activity against multidrug resistant Escherichia coli DH5[alpha] by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1473740 | Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 10 mins by membrane vesicle transport assay | 2013 | Toxicological sciences : an official journal of the Society of Toxicology, Nov, Volume: 136, Issue:1 | A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. |
| AID562782 | Antimicrobial activity against Chlamydia trachomatis L2/oflR harboring ompA gene | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID522667 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis K8091 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID585858 | Antimicrobial activity against Pseudomonas aeruginosa isolate 9 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID625286 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID534346 | Antimicrobial activity against Burkholderia pseudomallei Bp207 harboring deleted (bpeAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID585847 | Antimicrobial activity against Pseudomonas aeruginosa isolate 4 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID561099 | Antibacterial activity against Pasteurella multocida ATCC 43137 by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID1672290 | Antibacterial activity against Pseudomonas aeruginosa assessed as bacterial growth inhibition after 24 hrs by CLSI protocol based broth microdilution assay | |||
| AID283552 | Antimicrobial activity against Streptococcus pneumoniae PC13 isolate with erm(B) mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID522643 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis Sterne by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID530235 | Antimicrobial activity against Mycobacterium bovis BCG ML1034 by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID278231 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21 tolC::Kan | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID565633 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 assessed as growth inhibition at 0.7 ug/ml | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID540211 | Fraction unbound in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID540836 | Antimicrobial activity against ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 5408-cip harboring gyrA D87Y, gyrB E466D, parE V461G mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID585421 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W322-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID554652 | Antimicrobial activity against Ureaplasma parvum SV1 isolate HPA18 after 48 hrs by modified broth microdilution technique | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance. |
| AID250257 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH01; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID1474167 | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring verified drug-induced liver injury concern status | 2016 | Drug discovery today, Apr, Volume: 21, Issue:4 | DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. |
| AID425589 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease in mouse J774A1 cells assessed as intracellular killing of bacteria at 1.7 ug/ml after 3 h | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID524638 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea assessed as incidence of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID554863 | Antimicrobial activity against Streptococcus pneumoniae serotype 19F ST 236 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID554864 | Antimicrobial activity against Streptococcus pneumoniae serotype 19F ST 271 harboring ERY-resistant erm(B) and mef(E) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID556669 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 24 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID584820 | Effect on Pseudomonas putida PAW340 biofilms assessed as heat production at 70 ug/ml by Chip calorimetry | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Chip calorimetry for fast and reliable evaluation of bactericidal and bacteriostatic treatments of biofilms. |
| AID671558 | Antibacterial activity against Staphylococcus aureus ATCC 13709 infected in po dosed CD-1 mouse assessed as increase in survival administered as single dose 1 hr post infection measured after 48 hrs post infection | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID530428 | Antimicrobial activity against Mycobacterium smegmatis overexpressing rv0194 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID721791 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as growth inhibition after 24 hrs by CLSI broth microdilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. |
| AID307122 | Inhibition of HIV1 recombinant integrase strand transfer activity | 2007 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 17, Issue:8 | Newer tetracycline derivatives: synthesis, anti-HIV, antimycobacterial activities and inhibition of HIV-1 integrase. |
| AID556668 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 23 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID563502 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 71 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID671560 | Oral bioavailability in rat | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID1250084 | Antibacterial activity against Klebsiella pneumoniae ATCC 700603 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID323905 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC G155R mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID556903 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 15 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1325497 | Antibacterial activity against oxacillin/tetracycline-resistant Staphylococcus aureus NRS-100 | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: Modifications at C-12. |
| AID428292 | Antimicrobial activity against Acinetobacter baumannii BM4579 expressing deltaadeIJK genes isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID283168 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL5256 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID396033 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pBGS18 plasmid by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID556880 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 20 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565816 | Antimicrobial activity against Neisseria gonorrhoeae assessed as resistant isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Update on fusidic acid (CEM-102) tested against Neisseria gonorrhoeae and Chlamydia trachomatis. |
| AID1820909 | Antibacterial activity against Enterococcus faecium assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID360366 | Antimalarial activity after 96hrs against Plasmodium falciparum 7G8 by [3H]hypoxanthine uptake | 2007 | The Journal of biological chemistry, Jan-26, Volume: 282, Issue:4 | In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. |
| AID547756 | Antimicrobial activity against invasive Streptococcus intermedius obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on brain heart infusion agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID688533 | Antibacterial activity against Enterococcus faecalis ATCC 29212 | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Antibacterial spirobisnaphthalenes from the North American cup fungus Urnula craterium. |
| AID522659 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis 003BS by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID1756237 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as bacterial growth inhibition measured after 16 hrs by serial dilution method | 2021 | Journal of natural products, 02-26, Volume: 84, Issue:2 | Hydrated Rubrolides from the New Zealand Tunicate |
| AID377751 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assay | 2006 | Journal of natural products, Jul, Volume: 69, Issue:7 | Antibiotic bisanthraquinones produced by a streptomycete isolated from a cyanobacterium associated with Ecteinascidia turbinata. |
| AID564814 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID360849 | Antibacterial activity against Escherichia coli ATCC 25922 at 30 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID565041 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID743656 | Antibacterial activity against Escherichia coli EB2120 conditional lolA strain with lolA deletion and complementing copy placed at araBAD locus at 1 to 256 ug/mL after 18 hrs in presence of 0.00002 to 0.2% of arabinose | 2013 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 23, Issue:8 | Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA. |
| AID565437 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 biofilm assessed as biofilm bacterial count at 0.07 ug/ml (Rvb =402.9 +/- 26.88 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1325495 | Antibacterial activity against aminoglycosides/tetracycline-resistant Staphylococcus aureus NRS-1 | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: Modifications at C-12. |
| AID323635 | Antimicrobial activity against group A streptococci assessed as percent resistant isolates by Etest | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Tetracycline resistance in group a streptococci: emergence on a global scale and influence on multiple-drug resistance. |
| AID559329 | Antimicrobial activity against Salmonella enterica serovar Virchow assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID1159089 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 assessed as zone of inhibition at 30 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID454155 | Antimicrobial activity against Escherichia coli MTCC 1650 at 10 ug/ml after 24 hrs by agar diffusion method | 2009 | Bioorganic & medicinal chemistry, Dec-15, Volume: 17, Issue:24 | Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents. |
| AID501864 | Antifungal activity against Acremonium chrysogenum isolates after 48 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID646213 | Antibacterial activity against Escherichia coli ATCC 107 25922 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID1338321 | Antibacterial activity against Proteus vulgaris PCM 2668 after 20 hrs by microbroth dilution method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | New family of antimicrobial agents derived from 1,4-naphthoquinone. |
| AID1821098 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID559601 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutY mutant gene selected in presence of ciprofloxacin by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID575166 | Inhibition of acrAB AcrAB-TolC in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as [3H]TMG accumulation at 800 uM by scintillation counter method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID425612 | Cytotoxicity against mouse J774A1 cells assessed as release of adenylate kinase at 100 ug/ml after 3 hrs by total cell protein assay relative to control | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID587843 | AUC in Sprague-Dawley rat at 1 mg/kg, iv and 10 mg/kg, po | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID572803 | Antimicrobial activity against ramR-deficient Salmonella enterica serovar Typhimurium S/921495 harboring plasmid encoded RamR gene by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID585855 | Antimicrobial activity against Pseudomonas aeruginosa isolate 8 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1131171 | Antibacterial activity against Pasteurella multocida MB7 assessed as growth inhibition at 2 to 8 ug/mL | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID545042 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ043 from patient abdominal drainage by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID1551807 | Antibacterial activity against Bacillus subtilis incubated for 18 hrs post 30 mins pre-diffusion by disk diffusion method | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID406147 | Antimicrobial activity against Bacillus megaterium by agar diffusion method | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi. |
| AID1278314 | Antibacterial activity against acrAB and acrEF knock-out Escherichia coli BL21 by microbroth dilution assay | 2016 | European journal of medicinal chemistry, Mar-03, Volume: 110 | Design, synthesis and biological evaluation of monobactams as antibacterial agents against gram-negative bacteria. |
| AID558076 | Cytotoxicity against normal human epidermal keratinocytes at 10 uM after 72 hrs by MTT assay | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes. |
| AID559602 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutM mutant gene selected in presence of ciprofloxacin by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID532021 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H containing pCK0601 carrying the luxAB gene under the hsp60 promoter after 14 days determined according to CFU counts by bioluminescence method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID721789 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 assessed as growth inhibition after 24 hrs by CLSI broth microdilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. |
| AID667267 | Antibacterial activity against Pseudomonas aeruginosa at 500 ug/ml after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. |
| AID543364 | Antimicrobial activity against tetracycline-susceptible Salmonella sp. Isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID625506 | Antimicrobial activity against Bacillus thuringiensis after 24 hrs by spectrophotometry | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Green synthesis and antimicrobial evaluation of some new trifluoromethyl-substituted hexahydropyrimidines by grinding. |
| AID1592957 | Antibacterial activity against multi-drug resistant Escherichia coli NMI 3548/14 assessed as reduction in microbial growth incubated for 20 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. |
| AID1698048 | Antibacterial activity against Staphylococcus aureus assessed as inhibition of bacterial growth incubated for overnight by CLSI based method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID569298 | Antibacterial activity against Proteus mirabilis at 75 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID285851 | Antimicrobial activity against erythromycin-resistant Streptococcus pyogenes E-115 transconjugated with erm(B) and tet(M) genes | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID545048 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ210 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID629284 | Antibacterial activity against Photobacterium leiognathi Sh1 assessed as inhibition of bacterial luminescence at 0.1 mg/mL after 10 mins by bioluminometry-based acute action test | 2011 | European journal of medicinal chemistry, Dec, Volume: 46, Issue:12 | Synthesis and biological activity of novel N-cycloalkyl-(cycloalkylaryl)-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-yl)thio]acetamides. |
| AID283171 | Decrease in biofilm formation of Staphylococcus lugdunensis assessed as percent biofilm forming isolates | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID510559 | Antibacterial activity against Escherichia coli AG102MB | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID250258 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH02; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID524673 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ mutant gene assessed as percentage intermediate isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID501863 | Antifungal activity against Aspergillus restrictus isolates after 48 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID1304852 | Ratio of MIC for methicillin-resistant Staphylococcus aureus clinical isolate 2 in absence and presence of Fe2+ | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID1225258 | Antimicrobial activity against Klebsiella pneumoniae ATCC 13883 assessed as bacterial growth inhibition after 24 hrs by standard broth microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 25, Issue:1 | A potent antimicrobial compound isolated from Clathria cervicornis. |
| AID1681015 | Antibacterial activity against Pseudomonas aeruginosa assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID569299 | Antibacterial activity against Proteus mirabilis at 100 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID395375 | Antibacterial activity against Micrococcus luteus La 2971 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID563500 | Antimicrobial activity against Serratia marcescens ATCC 13880 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID529902 | Antimicrobial activity against Leptospira interrogans serovar Pomona isolate 12 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID1473738 | Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to 20 mins by membrane vesicle transport assay | 2013 | Toxicological sciences : an official journal of the Society of Toxicology, Nov, Volume: 136, Issue:1 | A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. |
| AID323019 | Antibacterial activity against drug-resistant Propionibacterium acnes SW101T after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID548473 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID1592960 | Antibacterial activity against multi-drug resistant Klebsiella pneumoniae NMI 3081/09 assessed as reduction in microbial growth incubated for 20 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. |
| AID585845 | Antimicrobial activity against Pseudomonas aeruginosa isolate 3 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID556653 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 8 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID325008 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 426 isolate with erm(B) resistance gene from patient sinuitis by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID377750 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 18 hrs by broth dilution assay | 2006 | Journal of natural products, Jul, Volume: 69, Issue:7 | Antibiotic bisanthraquinones produced by a streptomycete isolated from a cyanobacterium associated with Ecteinascidia turbinata. |
| AID1347488 | Antibacterial activity against Staphylococcus aureus assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID594272 | Antimicrobial activity against Bacillus subtilis NCIM 2063/ATCC 6633 at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID1329751 | Antibacterial activity against Salmonella typhimurium ATCC 13311 after 24 hrs by broth microdilution method | |||
| AID572596 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium 102SA00 harboring GyrA S83A and D87N, GyrB S464F and ParC S80I mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID584830 | Antibacterial activity against Pseudomonas aeruginosa | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Chip calorimetry for fast and reliable evaluation of bactericidal and bacteriostatic treatments of biofilms. |
| AID1592958 | Antibacterial activity against multi-drug resistant Escherichia coli NMI 3898/15 assessed as reduction in microbial growth incubated for 20 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. |
| AID693554 | Antibacterial activity against Salmonella typhimurium after 48 hrs by well diffusion assay | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Facile water promoted synthesis of 1,2,3-triazolyl dihydropyrimidine-2-thione hybrids - highly potent antibacterial agents. |
| AID283560 | Antibacterial activity against Escherichia coli HNCE4 after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. |
| AID285844 | Antimicrobial activity against tetracycline-susceptible Streptococcus pyogenes cMLS isolate F | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. |
| AID554878 | Antimicrobial activity against Streptococcus pneumoniae serotype 10 ST 461 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID565070 | Antibacterial activity against CTX-M-14 ESBL producing Klebsiella pneumoniae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID420023 | Antibacterial activity against Pseudomonas aeruginosa at 20 mg/mL by agar diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Novel pyridazine derivatives: Synthesis and antimicrobial activity evaluation. |
| AID1079942 | Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source] | |||
| AID556867 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 7 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID649514 | Antimicrobial activity against Staphylococcus aureus ATCC 29523 after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry, Mar-15, Volume: 20, Issue:6 | Efficient synthesis and biological evaluation of proximicins A, B and C. |
| AID1514479 | Antibacterial activity against Staphylococcus aureus after 24 hrs | 2018 | Bioorganic & medicinal chemistry, 12-15, Volume: 26, Issue:23-24 | Isolation and structure determination of a new lasso peptide specialicin based on genome mining. |
| AID556906 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes ATCC 15038 harboring pDrive plasmid by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1254823 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 12 hrs by agar diffusion method | 2015 | Journal of natural products, Oct-23, Volume: 78, Issue:10 | Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion. |
| AID532018 | Antibacterial activity against macrolide-lincosamide-streptogramin B-negative, beta-lactamase-positive, methicillin-susceptible Staphylococcus aureus ATCC 29213 | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Combined antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone-spermine conjugate. |
| AID428139 | Antimicrobial activity against wild-type Streptococcus pneumoniae PC13 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. |
| AID562789 | Antimicrobial activity against Chlamydia trachomatis L2/tetR13 harboring tet(C) allele | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID467964 | Antimicrobial activity against Escherichia coli ATCC 11775 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID533663 | Antimicrobial activity against Staphylococcus aureus RN1024 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID547534 | Antimicrobial activity against invasive Streptococcus anginosus obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of 5 | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID353047 | Antimicrobial activity against Proteus mirabilis at 100 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID572804 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID425398 | Antibacterial activity against Escherichia coli isolate HM154 isolated from colonic mucosal biopsies of patient with Crohn's disease after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID625284 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID425602 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate LF82 in mouse J774A1 cells isolated from chronic ileal lesions of patient with Crohn's disease assessed as intracellular killing of bacteria at 10% compound Cmax after | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID587245 | Antimicrobial activity against Escherichia coli DSM 682 after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID1348083 | Antimicrobial activity against Candida parapsilosis ATCC 90018 assessed as zone of inhibition at 50 ug per disc after 48 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID501848 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID293956 | Reduction of IL1-beta plus AMPA-induced proteoglycan degradation in rabbit articular cartilage at 200 uM relative to control | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6 | Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases. |
| AID1061188 | Antimicrobial activity against Escherichia coli MTCC 724 at 100 ug/ml after 24 hrs by disc diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation. |
| AID325010 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 443 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID275054 | Antibacterial activity against Escherichia coli W3110 | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25 | Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin. |
| AID295096 | Antibacterial activity against Escherichia coli ATCC 11230 at 30 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID353052 | Antimicrobial activity against Salmonella typhi at 25 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID1231528 | Antibacterial activity against Erwinia carotovora CECT 225 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter broth dilution method | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antibacterial activities of cadiolides A, B and C and analogues. |
| AID574545 | Antimicrobial activity against community-associated methicillin-resistant Staphylococcus aureus USA300 | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID87952 | Minimum inhibitory concentration against Helicobacter pylori (Helicobacter pylori) ARHp strain 80 | 2002 | Journal of medicinal chemistry, Sep-12, Volume: 45, Issue:19 | Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 2. |
| AID501861 | Antifungal activity against Candida albicans ATCC 10231 after 48 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID556659 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 14 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1678759 | Antibacterial activity against Klebsiella pneumoniae ATCC 700603 using cyrene as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID534828 | Antimicrobial activity against kanamycin-resistant Campylobacter fetus subsp. fetus CA76 harboring deletion in ant(6)-Ib::pCA76 in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID1131160 | Antibacterial activity against Pseudomonas aeruginosa MB418 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID278665 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5737 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID1376893 | Antimicrobial activity against Bacillus cereus DSM 4313 assessed as growth inhibition at 7 ug per disc after 24 to 48 hrs (Rvb = 0 millimeter) | |||
| AID405427 | Antibacterial activity against Pseudomonas aeruginosa PAO1 by Etest | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Influence of high mutation rates on the mechanisms and dynamics of in vitro and in vivo resistance development to single or combined antipseudomonal agents. |
| AID522876 | Antibacterial activity against uropathogenic Escherichia coli UTI89 infected in human 5637 cells assessed as decrease in intracellular bacterial level at 250 to 300 ug/ml after 12 hrs by serial dilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID375433 | Displacement of [3H]PSB0413 from human platelet P2Y12 receptor | 2009 | Journal of medicinal chemistry, Jun-25, Volume: 52, Issue:12 | High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. |
| AID1056845 | Antibacterial activity against TEM-1/SHV-12 expressing Enterobacter cloacae isolate 306 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID1335591 | Antibacterial activity against methicillin sensitive Staphylococcus aureus ATCC 25923 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID495518 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4676 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID522664 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis BA1024 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID278266 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS18 acrAB::Kan with GyrA S38F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID520398 | Antibacterial activity against mef-positive Streptococcus pneumoniae isolates assessed as resistance incidence by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID559343 | Antimicrobial activity against Shigella sonnei harboring tetA gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID299671 | Antibacterial activity against Staphylococcus aureus by disk diffusion method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID644017 | Antimicrobial activity against Bacillus subtilis at 100 ug/ml by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3 | An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents. |
| AID585432 | Antimicrobial activity against oqxAB positive Escherichia coli DH5[alpha] harboring pMD18-T::oqxAB by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID311292 | Antibacterial activity against Proteus mirabilis at pH 7 | 2007 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18 | Synthesis and antibacterial activity of some novel chiral fluorophoric biscyclic macrocycles. |
| AID1412151 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by microbroth dilution method | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID1055419 | Antibacterial activity against multidrug and vancomycin-resistant Enterococcus faecalis UW 2689 assessed as growth inhibition by broth microdilution method | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Inducing secondary metabolite production by the endophytic fungus Fusarium tricinctum through coculture with Bacillus subtilis. |
| AID1131165 | Antibacterial activity against Salmonella schottmuelleri MB2837 assessed as growth inhibition | 1979 | Journal of medicinal chemistry, Nov, Volume: 22, Issue:11 | Antibacterial N-[omega, omega'-bis(alicyclic and aryl)-sec-alkyl]poly(methylene)triamine and -tetramine hydrochloride salts. |
| AID372899 | Antibacterial activity against Escherichia coli ATCC 35218 after 24 hrs by MTT assay | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. |
| AID428427 | Antibacterial activity against Proteus vulgaris after 24 hrs by well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of novel carbazole based macrocyclic amides as potential antimicrobial agents. |
| AID528915 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae expressing beta-lactamase CTX-M-3, CTX-M-15 and CTX-M-55 and other bla gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID323010 | Antibacterial activity against drug-resistant Propionibacterium acnes GE4E after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID295114 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 at 30 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID522662 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis K7038 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID1888848 | Antibacterial activity against Staphylococcus aureus K1758 measured after 24 hrs by Muller Hinton broth based MTT assay | 2022 | Bioorganic & medicinal chemistry, 01-15, Volume: 54 | Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor. |
| AID587831 | Antibacterial activity against tetracycline-resistant Staphylococcus aureus isolate 161 harboring tet(M) gene by CLSI M07-A8 method | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID342683 | Antimicrobial activity against CTX-M extended-spectrum beta-lactamase producing commensal Escherichia coli isolates from healthy children assessed as percent resistant isolates by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Rapid dissemination and diversity of CTX-M extended-spectrum beta-lactamase genes in commensal Escherichia coli isolates from healthy children from low-resource settings in Latin America. |
| AID1681020 | Antibacterial activity against Salmonella typhi ATCC 9207 by CLSI method | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID569311 | Antibacterial activity against Staphylococcus aureus at 100 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID1112107 | Antimicrobial activity against Bacillus megaterium by agar diffusion test | 2012 | Fitoterapia, Apr, Volume: 83, Issue:3 | Pyrenocines J-M: four new pyrenocines from the endophytic fungus, Phomopsis sp. |
| AID322998 | Antibacterial activity against drug-resistant Propionibacterium acnes SW11 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID609166 | Antibacterial activity against Streptococcus entericus assessed as zone of inhibition at 5 uL and 32 degC after 36 hrs by disk diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone. |
| AID556877 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 17 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1525332 | Antibacterial activity against Escherichia coli 121 after 20 hrs by CLSI-based microdilution method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance. |
| AID1079933 | Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is | |||
| AID278864 | Increase in lactate production in primary human osteoblasts at 190 ug/ml by ELISA | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID278243 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-3 tolC::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1681012 | Antibacterial activity against Enterobacter aerogenes assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID688530 | Antibacterial activity against Staphylococcus aureus ATCC 29213 | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Antibacterial spirobisnaphthalenes from the North American cup fungus Urnula craterium. |
| AID1159082 | Antimicrobial activity against Salmonella typhimurium ATCC 14028 assessed as zone of inhibition at 30 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID283163 | Antimicrobial susceptibility of Staphylococcus lugdunensis IDRL2639 biofilms after 24 hrs assessed as bacterial regrowth | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID495517 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4675 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID1142218 | Antimicrobial activity against Helicobacter pylori isolated from gastrointestinal disease patient after 72 hrs by Etest method | 2014 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 24, Issue:11 | Development of bacterial transglycosylase inhibitors as new antibiotics: moenomycin A treatment for drug-resistant Helicobacter pylori. |
| AID545046 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ085 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID460629 | Antifungal activity against Trichoderma viride MTCC 167 at 100 ug/ml after 48 hrs agar diffusion method | 2010 | Bioorganic & medicinal chemistry, Mar-01, Volume: 18, Issue:5 | Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. |
| AID1496309 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 342B after 24 hrs | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID561736 | Antibacterial activity against Beta-hemolytic Streptococcus group B assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID1442622 | Antibacterial activity against gram-negative Klebsiella pneumoniae KP153 harboring tet(A) by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID278245 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-4 gyrA+ with ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID559598 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring DNA oxidative repair system mutM mutant gene selected in presence of tobramycin by Etest | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. |
| AID568333 | Antimicrobial activity against multidrug-resistant Pseudomonas aeruginosa by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID569304 | Antibacterial activity against Salmonella typhi at 25 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID557394 | Antibacterial activity against Beta-lactamase-negative Neisseria meningitidis assessed as percent resistant isolates by Etest method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. |
| AID563513 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens 011 harboring plasmid STV28 expressing sdeB gene by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID572815 | Antimicrobial activity against Salmonella enterica serovar Typhimurium BN18/71 harboring plasmid encoded RamR gene, GyrA G81C,acrR mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID524885 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing rpsJ and penB mutant gene assessed as incidence of resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID585872 | Antimicrobial activity against Pseudomonas aeruginosa isolate 16 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1820908 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID322999 | Antibacterial activity against drug-resistant Propionibacterium acnes EG3NS after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID498788 | Antimicrobial activity against macrolide-resistant Streptococcus pyogenes emm77/ST399/T28 expressing tetM gene by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain. |
| AID535638 | Antimicrobial activity against Group B streptococcus serotype VI R2 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1412148 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 15 after 24 hrs by microbroth dilution method | 2018 | MedChemComm, Jan-01, Volume: 9, Issue:1 | Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics. |
| AID556651 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 6 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1636356 | Drug activation in human Hep3B cells assessed as human CYP2C9-mediated drug metabolism-induced cytotoxicity measured as decrease in cell viability at 300 uM pre-incubated with BSO for 18 hrs followed by incubation with compound for 3 hrs in presence of NA | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. |
| AID565065 | Antibacterial activity against CTX-M-14 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID250266 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH19; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID420021 | Antibacterial activity against Streptococcus faecalis at 20 mg/mL by agar diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Novel pyridazine derivatives: Synthesis and antimicrobial activity evaluation. |
| AID1058231 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by CLSI method | 2013 | Bioorganic & medicinal chemistry, Dec-15, Volume: 21, Issue:24 | Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis. |
| AID542389 | Antimicrobial activity against Staphylococcus aureus RN4220 transformed with Staphylococcus aureus ST9 plasmid pSCFS3 carrying cfr and fexA genes | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID533661 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring plasmid CU1 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID395370 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID358252 | Antibacterial activity against Cryptococcus neoformans ATCC 90113 after 48 hrs by microplate assay | 2001 | Journal of natural products, Oct, Volume: 64, Issue:10 | Antimalarial (+)-trans-hexahydrodibenzopyran derivatives from Machaerium multiflorum. |
| AID489645 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID554874 | Antimicrobial activity against Streptococcus pneumoniae serotype 14 ST 2678 harboring ERY-resistant erm(B) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID290123 | Inhibition of protein synthesis in Escherichia coli by coupled transcription-translation assay | 2007 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 17, Issue:5 | Synthesis and SAR of 3,5-diamino-piperidine derivatives: novel antibacterial translation inhibitors as aminoglycoside mimetics. |
| AID739303 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 assessed as growth inhibition by CLSI broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. |
| AID315457 | Toxicity in human erythrocytes assessed as hemolysis upto 3.91 ug/mL | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of 3-arylamino-1-chloropropan-2-ols. |
| AID540929 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor KO-347 harboring rpsl P91S mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID609170 | Antifungal activity against Hyphopichia burtonii assessed as zone of inhibition at 5 uL and 28 degC after 36 hrs by disk diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone. |
| AID1127621 | Antibacterial activity against fluoroquinolone-resistant Streptococcus pneumoniae D39 NCTC 7466 expressing GyrA S81F/ParC S79F double mutant assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21 | Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
| AID1228683 | Antibacterial activity against tet(M) tetracycline-resistant Enterococcus faecalis 327 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID1681016 | Antibacterial activity against Shigella boydii assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID323032 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID324198 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid PhoU at 12.5 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID522665 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis BA0018 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID388081 | Antifungal activity at Candida albicans | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents. |
| AID542385 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ST398 expressing cfr, fexA, erm(A), tet(M) and mecA genes | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID547523 | Antimicrobial activity against Streptococcus constellatus obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on brain heart infusion agar at 30 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID1240027 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as concentration required to completely destroy test microorganisms after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 25, Issue:17 | Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening. |
| AID278684 | Antibacterial activity against Enterococcus faecalis isolate 5746 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID323030 | Antibacterial activity against Staphylococcus epidermidis after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID374169 | Antibacterial activity against Streptococcus mutans ATCC 33402 biofilms assessed as log reduction of viable bacteria at 500 ug/ml | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens. |
| AID308343 | Antibacterial activity against Pseudomonas aeruginosa MTCCB 741 | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID594335 | Antimicrobial activity against Escherichia coli NCIM 2068/ATCC 11105 at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID532031 | Antimicrobial activity against Escherichia coli TOP10F' by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID388001 | Antibacterial activity against Bacillus cereus ATCC 11778 after 24 hrs by microdilution broth method | 2008 | Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22 | Structure-activity relationship of antibacterial chalcones. |
| AID601195 | Elimination half life in Sprague-Dawley rat at 1 mg/kg, iv administered as single dose | 2011 | Journal of medicinal chemistry, Jun-09, Volume: 54, Issue:11 | Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs. |
| AID781325 | pKa (acid-base dissociation constant) as determined by Liao ref: J Chem Info Model 2009 | 2014 | Pharmaceutical research, Apr, Volume: 31, Issue:4 | Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. |
| AID556680 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 7 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID293952 | Inhibition of human MMP2 | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6 | Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases. |
| AID447074 | Antibacterial activity against Bacillus cereus ATCC 7064 at 30 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID1228684 | Antibacterial activity against tet(M) tetracycline-resistant Enterococcus faecium 404 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID556893 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 5 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID396029 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate in presence of 20 ug/ml efflux pump inhibitor Phe-Arg-beta-naphthylamide by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID409958 | Inhibition of bovine brain MAOA | 2008 | Journal of medicinal chemistry, Nov-13, Volume: 51, Issue:21 | Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. |
| AID530582 | Antimicrobial activity against macrolide-resistant Mycoplasma pneumoniae isolate 11 with A2604G mutation by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID556688 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 15 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID565324 | Antibacterial activity against Mycoplasma genitalium M6286 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID721790 | Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 assessed as growth inhibition after 24 hrs by CLSI broth microdilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. |
| AID1678767 | Antibacterial activity against Enterococcus faecalis ATCC 51299 using DMSO as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID572807 | Antimicrobial activity against ramA::kan-deficient Salmonella enterica serovar Typhimurium BN18 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1159092 | Antimicrobial activity against Bacillus thuringiensis assessed as zone of inhibition at 30 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID324195 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid vector at 50 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1149689 | Antimicrobial activity against Agrobacterium tumefaciens assessed as growth inhibition after 24 hrs by two-fold serial dilution technique | 1977 | Journal of medicinal chemistry, Jun, Volume: 20, Issue:6 | Synthesis of 5-chloro-3'-nitro-4'-substituted salicylanilides, a new series of anthelmintic and antimicrobial agents. |
| AID283551 | Antimicrobial activity against Streptococcus pneumoniae PC13 transformants | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID1335602 | Antibacterial activity against multi-drug resistant Pseudomonas aeruginosa MFBF after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID1698040 | Antibacterial activity against Escherichia coli assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID522648 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis Africa 33 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID545054 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ390 from patient secretion by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID544280 | Antimicrobial activity against Enterococcus faecalis NKH10 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID539665 | Antimicrobial activity against Staphylococcus aureus by well diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno[3,4-b]pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens. |
| AID588114 | Antimicrobial activity against Neisseria gonorrhoeae clinical isolates assessed as percent susceptible isolates after 24 hrs by agar dilution method | 2011 | Antimicrobial agents and chemotherapy, Feb, Volume: 55, Issue:2 | Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. |
| AID1525328 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 757 after 20 hrs by CLSI-based microdilution method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance. |
| AID565327 | Antibacterial activity against Mycoplasma genitalium M6151 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID428294 | Antimicrobial activity against Acinetobacter baumannii BM4652 expressing adeIJK genes with pAT807 isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID278236 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-2 with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1124944 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as growth inhibition after 16 to 20 hrs by microbroth dilution method | 2014 | Bioorganic & medicinal chemistry, Apr-01, Volume: 22, Issue:7 | Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines. |
| AID1678764 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27893 using DMSO as solvent by broth microdilution method | 2020 | RSC medicinal chemistry, Jan-01, Volume: 11, Issue:1 | Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. |
| AID530579 | Antimicrobial activity against Mycoplasma pneumoniae isolate M129 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID534164 | Antimicrobial activity against Campylobacter coli by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Comparison of disk diffusion and agar dilution methods for erythromycin, ciprofloxacin, and tetracycline susceptibility testing of Campylobacter coli and for tetracycline susceptibility testing of Campylobacter jejuni subsp. jejuni. |
| AID572797 | Antimicrobial activity against marR::kan-deficient Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID369658 | Antibacterial activity against Campylobacter jejuni 25-45 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. |
| AID765062 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. |
| AID529553 | Antimicrobial activity against Bacillus anthracis MurA1 AS clone 2G2 assessed as growth inhibition in absence of xylose by antisense-induced hypersensitive testing | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Comparison of the essential cellular functions of the two murA genes of Bacillus anthracis. |
| AID585428 | Antimicrobial activity against oqxAB positive Escherichia coli C600 SW8-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID680947 | TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2alpha: 0.005 uM, Tetracycline: 5 uM) in OAT2-expressing S2 cells | 2002 | Japanese journal of pharmacology, Jan, Volume: 88, Issue:1 | Human organic anion transporters mediate the transport of tetracycline. |
| AID353055 | Antimicrobial activity against Salmonella typhi at 100 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID1577572 | Antibacterial activity against Pseudomonas viridiflava assessed as inhibition of bacterial growth after 24 hrs by microdilution method | |||
| AID562785 | Antimicrobial activity against Chlamydia muridarum MoPn/oflR harboring ompA gene | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Horizontal transfer of tetracycline resistance among Chlamydia spp. in vitro. |
| AID565316 | Antibacterial activity against Mycoplasma genitalium UTMB-10G by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR. |
| AID563505 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens 01 harboring plasmid STV29 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID325015 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 811 isolate with erm(B) resistance gene from patient blood by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID543343 | Antimicrobial activity against Vibrio cholerae non-O1 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID548739 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID428293 | Antimicrobial activity against Acinetobacter baumannii BM4651 expressing deltaadeIJK genes isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID1731001 | Antibacterial activity against Escherichia coli DH5-alpha assessed as inhibition of bacterial growth measured after 18 hrs by two fold serial dilution method | 2021 | European journal of medicinal chemistry, Mar-05, Volume: 213 | Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules. |
| AID522650 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis K7978 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID396267 | Antibacterial activity against tetracycline-resistant Escherichia coli clinical isolates expressing tet(C) gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. |
| AID561656 | Induction of morphological changes in Helicobacter pylori by phase contrast microscopy | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Pyrazolopyrimidinediones are selective agents for Helicobacter pylori that suppress growth through inhibition of glutamate racemase (MurI). |
| AID342019 | Antibacterial activity against plasmid pK29 transconjugant Escherichia coli J53 by Etest | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae. |
| AID694392 | Bactericidal activity against Staphylococcus aureus CECT 86 at 0.2 mg/disk after 24 hrs by agar diffusion assay | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones. |
| AID548254 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID395373 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID348888 | Antibacterial activity against Streptococcus mutans PTCC 1601 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID694207 | Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 by CLSI broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 22, Issue:22 | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. |
| AID1681017 | Antibacterial activity against Salmonella enterica subsp. enterica serovar Abony assessed as diameter of inhibition zone at 1 mg/ml incubated for 24 hrs by agar well diffusion assay | 2020 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 30, Issue:19 | Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. |
| AID625285 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID323035 | Antibacterial activity against Streptococcus equi subsp. zooepidemicus after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1347490 | Antibacterial activity against Pseudomonas aeruginosa assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID565014 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID544004 | Antimicrobial activity against Aerococcus viridans isolate PGS22 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID524677 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing tetM mutant gene in combination with variants of other gene loci assessed as percentage intermediate isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID405929 | Antimicrobial activity against epidemic methicillin-resistant Staphylococcus aureus 15 containing mecA gene | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Inhibitors of bacterial multidrug efflux pumps from the resin glycosides of Ipomoea murucoides. |
| AID425401 | Antibacterial activity against Escherichia coli isolate HM615 isolated from colonic mucosal biopsies of patient with Crohn's disease after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID585850 | Antimicrobial activity against Pseudomonas aeruginosa isolate 5 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID531103 | Inhibition of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa TNP090 mutant harboring las and rhl gene at 0.125 ug/ml by Cat-2,3-diO reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID678714 | Inhibition of human CYP2C19 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 3-butyryl-7-methoxycoumarin as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID561734 | Antibacterial activity against Beta-hemolytic Streptococcus group B assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID585844 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID460801 | Antibacterial activity against Acinetobacter baumannii 3304 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID388082 | Antifungal activity at Cryptococcus neoformans | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents. |
| AID544279 | Antimicrobial activity against Enterococcus faecalis NKH9 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID594327 | Antimicrobial activity against Staphylococcus aureus NCIM 2079/ATCC 6538P at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID660264 | Ratio of MIC for wild type Escherichia coli HS414 to MIC for acrB-deficient Escherichia coli HS832 by agar dilution method | 2012 | European journal of medicinal chemistry, Jun, Volume: 52 | Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. |
| AID544025 | Antimicrobial activity against Acinetobacter calcoaceticus isolate C36 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID718414 | Antibacterial activity against log-phase vancomycin-sensitive Enterococcus faecalis ATCC 19433 assessed as growth inhibition after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. |
| AID1585460 | Antibacterial activity against aminoglycosides/tetracycline-resistant Staphylococcus aureus NRS-1 measured after 16 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Design, synthesis and evaluation of hybrid of tetrahydrocarbazole with 2,4-diaminopyrimidine scaffold as antibacterial agents. |
| AID556664 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 19 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID1228694 | Antibacterial activity against Burkholderia cenocepacia 240 assessed as bacterial growth inhibition by susceptibility testing assay | 2015 | Journal of medicinal chemistry, Jun-11, Volume: 58, Issue:11 | Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents. |
| AID609169 | Antifungal activity against Aspergillus niger assessed as zone of inhibition at 5 uL and 28 degC after 36 hrs by disk diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone. |
| AID285196 | Antimicrobial activity against Escherichia coli M074 mutant with AG100 lon2::IS186 acrR::IS genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID423154 | Antibacterial activity against Bifidobacterium thermophilum B0253 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Mosaic tetracycline resistance genes and their flanking regions in Bifidobacterium thermophilum and Lactobacillus johnsonii. |
| AID495510 | Antibacterial activity against Acinetobacter baumannii BM4454 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID378120 | Antimicrobial activity against Bacillus subtilis at 30 ug/disk by disk diffusion assay | 2005 | Journal of natural products, Jan, Volume: 68, Issue:1 | Cicadapeptins I and II: new Aib-containing peptides from the entomopathogenic fungus Cordyceps heteropoda. |
| AID1442624 | Antibacterial activity against gram-negative Proteus mirabilis PM122 by CLSI method | 2017 | Journal of medicinal chemistry, 03-23, Volume: 60, Issue:6 | Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. |
| AID1688645 | Antibacterial activity against Salmonella typhi ATCC 6539 assessed as diameter of inhibition zone at 0.5 mg/ml incubated for 24 hrs by agar diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID250269 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH22; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID554675 | Antimicrobial activity against Streptococcus pneumoniae serotype 19F ST 156 by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID586085 | Antimicrobial activity against verocytotoxin-producing Escherichia coli isolate O157 obtained from human assessed as percentage of resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID307415 | Antibacterial activity against Escherichia coli ATCC 25668 | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11 | Syntheses and antibacterial activity of phendioxy substituted cyclic enediynes. |
| AID584827 | Antibacterial activity against Escherichia coli | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Chip calorimetry for fast and reliable evaluation of bactericidal and bacteriostatic treatments of biofilms. |
| AID1304853 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate 2 incubated for 16 hrs by broth microdilution method | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID554861 | Antimicrobial activity against Streptococcus pneumoniae serotype 14 ST 2916 harboring ERY-resistant erm(B) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID572812 | Antimicrobial activity against Salmonella enterica serovar Typhimurium BN18/41 harboring plasmid encoded RamR gene, GyrA G81C,acrR mutant genes by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1688643 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as diameter of inhibition zone at 0.5 mg/ml incubated for 24 hrs by agar diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID1392010 | Antistaphylococcal activity against aminoglycosides/tetracycline-resistant Staphylococcus aureus NRS-1 after 18 hrs by two-fold serial dilution method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10 | The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid. |
| AID1149694 | Antimicrobial activity against Salmonella typhi assessed as growth inhibition at 0.78 ug/ml after 24 hrs by two-fold serial dilution technique | 1977 | Journal of medicinal chemistry, Jun, Volume: 20, Issue:6 | Synthesis of 5-chloro-3'-nitro-4'-substituted salicylanilides, a new series of anthelmintic and antimicrobial agents. |
| AID283656 | Increase in ROS levels in Escherichia coli K12 MG1655 assessed as ratio of ROS with antibiotic to ROS without antibiotic | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID404900 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB40 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID278230 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21 acrAB::Kan | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID572793 | Antimicrobial activity against multidrug-resistant Salmonella enterica serovar Typhimurium BN9181 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID444056 | Fraction escaping gut-wall elimination in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID323912 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC G152D, D159Y, G155R and H134N mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID539669 | Antimicrobial activity against Shigella sp. by well diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno[3,4-b]pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens. |
| AID444050 | Fraction unbound in human plasma | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID423152 | Antibacterial activity against Bifidobacterium thermophilum B0241 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Mosaic tetracycline resistance genes and their flanking regions in Bifidobacterium thermophilum and Lactobacillus johnsonii. |
| AID565231 | Antimicrobial activity against Mycobacterium chelonae 9917 harboring pZS01 carrying mspA gene by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID556905 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes ATCC 15038 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID556695 | Antimicrobial activity against multidrug resistant Escherichia coli DH5[alpha] harboring pDrive plasmid by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID534407 | Antibacterial activity against Escherichia coli EPI300 expressing tet(W) gene assessed as inhibition of bacterial growth at 80 ug/ml after 18 hrs in presence of 2.5 ug/ml efflux pump inhibitor CCCP | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones. |
| AID625288 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID311293 | Antibacterial activity against Pseudomonas aeruginosa at pH 7 | 2007 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18 | Synthesis and antibacterial activity of some novel chiral fluorophoric biscyclic macrocycles. |
| AID528786 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae assessed as resistant isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID532990 | Antibacterial activity against Klebsiella pneumoniae NCIM 2883 assessed as growth inhibition in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID565063 | Antibacterial activity against CTX-M-15 ESBL producing Enterobacter cloacae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID559330 | Antimicrobial activity against Salmonella enterica clinical isolates assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID563506 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 71 harboring plasmid STV29 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID1726825 | Antibacterial activity against Pseudomonas aeruginosa MTCC 2488 incubated for 14 to 16 hrs by micro broth dilution method | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6 | Sulfonium-based liposome-encapsulated antibiotics deliver a synergistic antibacterial activity. |
| AID1159085 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 assessed as zone of inhibition at 30 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID322996 | Antibacterial activity against drug-resistant Propionibacterium acnes EG13NS after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID341108 | Antibacterial activity against Escherichia coli 26R793 by Etest | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | First occurrence of an Escherichia coli clinical isolate producing the VIM-1/VIM-2 hybrid metallo-beta-lactamase VIM-12. |
| AID556894 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 6 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID531337 | Antibacterial activity against MeXAB-OprM deficient Pseudomonas aeruginosa TNP077 selected after 1.0 ug/ml of azithromycin by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa. |
| AID1514480 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs | 2018 | Bioorganic & medicinal chemistry, 12-15, Volume: 26, Issue:23-24 | Isolation and structure determination of a new lasso peptide specialicin based on genome mining. |
| AID532765 | Antimicrobial activity against Salmonella serovar Typhimurium SL1344 expressing ramA::aph-pTRC hisA:ramA mutant by broth dilution method in presence of IPTG | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. |
| AID560249 | Antibacterial activity against Staphylococcus aureus RN4220 harboring tet(L), dfrK gene by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID360381 | Antimalarial activity after 96 hrs against azithromycin-resistant Plasmodium falciparum 7G8 by [3H]hypoxanthine uptake | 2007 | The Journal of biological chemistry, Jan-26, Volume: 282, Issue:4 | In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. |
| AID508596 | Antibacterial activity against ciprofloxacin-resistant Salmonella enteritidis 5408 harboring gyrA D87Y mutant, gyrB E466D mutant, parE V461G mutant and ramR G25A mutant gene after 200 passages by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID557795 | Antimicrobial activity against Proteus mirabilis 06-489 isolated from infected human urinary tract by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID572796 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S/921495 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID367433 | Binding affinity to bone mineral hydroxyapatite assessed as binding index | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Bone selective effect of an estradiol conjugate with a novel tetracycline-derived bone-targeting agent. |
| AID585857 | Antimicrobial activity against Pseudomonas aeruginosa isolate 9 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID501847 | Antibacterial activity against Escherichia coli food isolate after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17 | Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). |
| AID524872 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing penA mutant gene assessed as incidence of resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID564819 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1551777 | Antibacterial activity against Escherichia coli assessed as zone of inhibition | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID495748 | Antimicrobial activity against Escherichia coli ATCC 25922 by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID569296 | Antibacterial activity against Proteus mirabilis at 25 ug/ml after 24 hrs agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines. |
| AID717273 | Antimicrobial activity against methicillin-sensitive Staphylococcus aureus 8325-4 by CLSI protocol based broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. |
| AID285205 | Antimicrobial activity against Escherichia coli AG112 mutant with marR genotype after 250 generations in 5 ug/ml presence of tetracycline | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID1392009 | Antistaphylococcal activity against Staphylococcus aureus Newman after 18 hrs by two-fold serial dilution method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10 | The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid. |
| AID323911 | Antibacterial activity against Staphylococcus aureus RN4220 with rplC G152D, D159Y and G155R mutation | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin. |
| AID335300 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum D6 | |||
| AID353045 | Antimicrobial activity against Proteus mirabilis at 50 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID561641 | Antibacterial activity against Staphylococcus aureus by CLSI M100-S13 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Pyrazolopyrimidinediones are selective agents for Helicobacter pylori that suppress growth through inhibition of glutamate racemase (MurI). |
| AID325024 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 1051 isolate with erm(B) resistance gene from patient ear by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID372896 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by MTT assay | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. |
| AID278680 | Antibacterial activity against Enterococcus faecium isolate 5751 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID484674 | Antibacterial activity against Proteus mirabilis | 2010 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 20, Issue:12 | Synthesis of novel beta-lactam fused spiroisoxazolidine chromanones and tetralones as potent antimicrobial agent for human and plant pathogens. |
| AID556881 | Antimicrobial activity against multidrug resistant Enterobacter aerogenes isolate 21 by broth dilution method in presence of 26.3 mg/L efflux pump inhibitor phenylalanine-arginine-beta-naphthylamide | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID295102 | Antibacterial activity against Klebsiella pneumoniae UC57 at 30 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID429853 | Antibacterial activity against Staphylococcus aureus XU-212 overexpressing TetK, mecA after 24 hrs | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6 | Antibacterial diterpenes from Plectranthus ernstii. |
| AID425620 | Cmax in patient with Billroth-II gastrectomy at 250 mg, po | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID572808 | Antimicrobial activity against Salmonella enterica serovar Typhimurium BN18/21 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID443283 | Antimicrobial activity against Bacillus subtilis after 24 hrs by agar dilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Anti-oxidant and anti-bacterial activities of novel N'-arylmethylidene-2-(3, 4-dimethyl-5, 5-dioxidopyrazolo[4,3-c][1,2]benzothiazin-2(4H)-yl) acetohydrazides. |
| AID444055 | Fraction absorbed in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID509630 | Antimicrobial activity against Staphylococcus aureus RN4220 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID91481 | Binding constant against human serum albumin (HSA) | 2001 | Journal of medicinal chemistry, Dec-06, Volume: 44, Issue:25 | Cheminformatic models to predict binding affinities to human serum albumin. |
| AID510748 | Antibacterial activity against Escherichia coli AG102MB harboring naive acrB gene | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID568330 | Antimicrobial activity against multidrug-resistant Escherichia coli by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID554858 | Antimicrobial activity against Streptococcus pneumoniae serotype 14 ST 2306 harboring ERY-resistant erm(B) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID56763 | Inhibition zone when tested against DAP-AT from Escherichia coli in M9-Minimal agar at concentration 3 ug | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8 | Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. |
| AID749306 | Bactericidal activity against Escherichia coli CECT 100 at 0.2 mg/disk after 24 hrs by paper disk-agar diffusion method | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11 | Novel isoquinoline derivatives as antimicrobial agents. |
| AID1428344 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs | 2016 | Journal of natural products, Dec-23, Volume: 79, Issue:12 | Antimicrobial Oligophenalenone Dimers from the Soil Fungus Talaromyces stipitatus. |
| AID524640 | Antimicrobial activity against Neisseria gonorrhoeae obtained from patient with uncomplicated gonorrhea expressing mtrR mutant gene assessed as incidence of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains. |
| AID1525334 | Antibacterial activity against Haemophilus influenzae 1244 after 20 hrs by CLSI-based microdilution method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance. |
| AID543345 | Antimicrobial activity against Aeromonas caviae assessed as percent tetracyclin-resistant isolate at 0.25 to >16 ug/ml by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID671556 | Antibacterial activity against Staphylococcus aureus ATCC 13709 infected in CD-1 mouse assessed as increase in survival at 3 mg/kg, iv administered as single dose 1 hr post infection measured after 48 hrs post infection | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID540209 | Volume of distribution at steady state in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID260689 | Antibacterial activity against Xanthomonas oryzae by disk diffusion method at 10 ug/disk | 2006 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 16, Issue:4 | Microwave-assisted synthesis of N-alkylated benzotriazole derivatives: antimicrobial studies. |
| AID544017 | Antimicrobial activity against Enterococcus sulfureus isolate PGS61 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1781497 | Anti-MDR bacterial activity against Escherichia coli CCARM 1009 assessed as inhibition of bacterial growth incubated for 18 hrs by microplate reader analysis | |||
| AID585853 | Antimicrobial activity against Pseudomonas aeruginosa isolate 7 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID557209 | Antibacterial activity against Beta-lactamase-negative Neisseria meningitidis assessed as percent susceptible isolates by Etest method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. |
| AID1634995 | Antimicrobial activity against Pseudomonas aeruginosa clinical isolates assessed as reduction in bacterial growth after 20 hrs by drop diffusion test | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics. |
| AID530349 | Antimicrobial activity against Escherichia coli TOP10 harboring pQep plasmid carrying qepA2 gene by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID283553 | Antimicrobial activity against Streptococcus pneumoniae PC13 isolate with L4 mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID278677 | Antibacterial activity against Enterococcus faecium isolate 2547 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID335299 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 | |||
| AID1726820 | Antibacterial activity against Staphylococcus aureus MTCC 96 incubated for 14 to 16 hrs by micro broth dilution method | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6 | Sulfonium-based liposome-encapsulated antibiotics deliver a synergistic antibacterial activity. |
| AID325027 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae 837 isolate with mutation in erm(B), mef(E), L4 Ser20Asn mutant gene from patient sputum by disk diffusion test | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Molecular epidemiology of telithromycin-resistant pneumococci in Finland. |
| AID749308 | Bactericidal activity against Escherichia coli CECT 405 at 0.2 mg/disk after 24 hrs by paper disk-agar diffusion method | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11 | Novel isoquinoline derivatives as antimicrobial agents. |
| AID529457 | Antimicrobial activity against Klebsiella pneumoniae containing PFGE clone B expressing beta-lactamase Oxa-48, TEM-1, CTX-M-15 and Oxa-1 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. |
| AID1335590 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 18 hrs by serial microdilution broth assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation. |
| AID1250085 | Antibacterial activity against Escherichia coli ATCC 25922 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID293958 | Inhibition of IL-1-beta-induced MMP13 production in human SW1353 cells at 50 uM | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6 | Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases. |
| AID543348 | Antimicrobial activity against Aeromonas caviae by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activities of tigecycline against clinical isolates of Aeromonas, Vibrio, and Salmonella species in Taiwan. |
| AID278263 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS14 tolC::Kan with GyrA D87G mutant | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID541855 | Antimicrobial activity against Escherichia coli ATCC 29522 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID287371 | Antibacterial activity against Escherichia coli after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID587838 | Inhibition of protein synthesis in Escherichia coli S30 extract by coupled transcription/translation assay | 2011 | Journal of medicinal chemistry, Mar-10, Volume: 54, Issue:5 | 8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents. |
| AID544288 | Antimicrobial activity against Enterococcus faecalis NKH18 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1593386 | Growth inhibition of Escherichia coli AB1157 | 2019 | Journal of medicinal chemistry, 04-11, Volume: 62, Issue:7 | Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. |
| AID530584 | Antimicrobial activity against Mycoplasma pneumoniae isolate 18 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. |
| AID323025 | MBC/MIC ratio of Propionibacterium acnes GE4E | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID572805 | Antimicrobial activity against Salmonella enterica serovar Typhimurium BN18 by agar doubling dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. |
| AID1238340 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by agar diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 25, Issue:16 | Antibacterial activity of diketopiperazines isolated from a marine fungus using t-butoxycarbonyl group as a simple tool for purification. |
| AID556683 | Antimicrobial activity against multidrug resistant Klebsiella pneumoniae isolate 10 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. |
| AID283175 | Stimulation of Staphylococcus lugdunensis IDRL5256 biofilm formation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. |
| AID1347486 | Antibacterial activity against Streptococcus pyogenes assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID646214 | Antibacterial activity against tetracycline-resistant Escherichia coli 155 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID520397 | Antibacterial activity against erm(B) and mef(E)-positive Streptococcus pneumoniae isolate Spain 6B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID1329754 | Antibacterial activity against Streptococcus mitis NCIMB 13770 after 24 hrs by broth microdilution method | |||
| AID548738 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID523004 | Antibacterial activity against uropathogenic Escherichia coli UTI89 assessed as degradation of preexisting biofilm after 24 hrs by microscopy | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID324192 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 at 50 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID353054 | Antimicrobial activity against Salmonella typhi at 75 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives. |
| AID554868 | Antimicrobial activity against Streptococcus pneumoniae serotype 23F ST 81 harboring ERY-resistant mef(E) gene by agar plate dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. |
| AID1311818 | Antibacterial activity against Burkholderia pseudomallei AHS 1 NCTC 8016 by two fold serial dilution method | 2016 | Bioorganic & medicinal chemistry, 09-15, Volume: 24, Issue:18 | Antibacterial and anticancer activity of a series of novel peptides incorporating cyclic tetra-substituted C(α) amino acids. |
| AID688534 | Antibacterial activity against Streptococcus pyogenes UWL | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Antibacterial spirobisnaphthalenes from the North American cup fungus Urnula craterium. |
| AID1348090 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition at 50 ug per disc after 24 hrs by disc diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID522661 | Antibacterial activity against beta-lactamase Bla1 and Bla2-producing Bacillus anthracis K1938 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. |
| AID1250086 | Antibacterial activity against Pseudomonas aeruginosa PAO1 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID369228 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae assessed as percent resistant isolates by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID646219 | Antibacterial activity against tetracycline-resistant Klebsiella pneumoniae 153 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. |
| AID542386 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ST9 expressing cfr, fexA and erm(C) genes | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID565031 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID535633 | Antimicrobial activity against Group B streptococcus serotype Ia R7 harboring T77I, F395V and S353F in PBP 2X; V80A and G613R in PBP 2B; and L45P, N163K, N723S and Y470F in PBP 1A by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1688646 | Antifungal activity against Candida albicans ATCC 10231 assessed as diameter of inhibition zone at 0.5 mg/ml incubated for 24 hrs by agar diffusion method | 2020 | European journal of medicinal chemistry, Feb-15, Volume: 188 | One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. |
| AID1698038 | Antibacterial activity against Bacillus subtilis assessed as inhibition of bacterial growth incubated for 24 hrs by agar well diffusion method | 2020 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 30, Issue:22 | Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents. |
| AID562811 | Antimicrobial activity against Escherichia coli J53 harboring pEK204 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID530236 | Resistance factor, ratio of MIC for Mycobacterium bovis BCG ML1034 to MIC for wild-type Mycobacterium bovis BCG | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID535646 | Antimicrobial activity against Group B Streptococcus serotype III NEM 316 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1820918 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as bacterial growth inhibition measured after 24 hrs by two fold serial dilution technique | 2022 | European journal of medicinal chemistry, Feb-05, Volume: 229 | An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a. |
| AID536632 | Antimicrobial activity against Staphylococcus aureus NCTC 7447 at 5 mg/ml after 24 hrs by agar well diffusion assay | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents. |
| AID544020 | Antimicrobial activity against Psychrobacter ikaite isolate C20 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID565191 | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 expressing open reading frame orf3 encoded efflux pump CraA by Etest | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii. |
| AID1243993 | Antimicrobial activity against Staphylococcus aureus by agar dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents. |
| AID323016 | Antibacterial activity against drug-resistant Propionibacterium acnes EG7NS after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1636376 | Drug activation in human Hep3B cells assessed as human CYP3A4-mediated drug metabolism-induced cytotoxicity measured as decrease in cell viability at 56.4 uM pre-incubated with BSO for 18 hrs followed by incubation with compound for 3 hrs in presence of N | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. |
| AID1672289 | Antibacterial activity against Escherichia coli assessed as bacterial growth inhibition after 24 hrs by CLSI protocol based broth microdilution assay | |||
| AID56759 | Inhibition zone when tested against DAP-AT from Escherichia coli in L-agar at concentration 3 ug | 1998 | Bioorganic & medicinal chemistry letters, Apr-21, Volume: 8, Issue:8 | Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. |
| AID671555 | Antibacterial activity against Klebsiella pneumoniae ATCC 13883 | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2 | Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. |
| AID325484 | Antibacterial activity against Escherichia coli N818 delta acrA mutant assessed as inhibition of AcrAB efflux pump after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID395371 | Antibacterial activity against Proteus vulgaris ATCC 8427 at 30 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID467969 | Antimicrobial activity against Bacillus cereus ATCC 14579 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID530345 | Antimicrobial activity against Escherichia coli BicA expressing blaTEM-1, blaCTX-M-15 and qepA2 gene by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347161 | Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1 | Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4 | A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347158 | ZIKV-mCherry secondary qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6 | A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID1347164 | 384 well plate NINDS Rhodamine confirmatory qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347163 | 384 well plate NINDS AMC confirmatory qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 11665 (58.11) | 18.7374 |
| 1990's | 1990 (9.91) | 18.2507 |
| 2000's | 2477 (12.34) | 29.6817 |
| 2010's | 2581 (12.86) | 24.3611 |
| 2020's | 1362 (6.78) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| This Compound (97.52) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 977 (4.54%) | 5.53% |
| Reviews | 983 (4.57%) | 6.00% |
| Case Studies | 1,144 (5.31%) | 4.05% |
| Observational | 12 (0.06%) | 0.25% |
| Other | 18,408 (85.52%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Helicobacter Pylori Eradication Using a Bismuth Quadruple Therapy Among Asymptomatically Infected Adults in El Paso, Texas: A Pilot Study. [NCT01335334] | Phase 4 | 50 participants (Anticipated) | Interventional | 2011-03-31 | Recruiting | ||
| Twice-a-day PPI, Tetracycline, Metronidazolequadruple Therapy With Pylera® or Lactobacillus Reuteri for Treatment naïve or for Retreatment of H. Pylori: Two Randomized Pilot Studies [NCT03925818] | 99 participants (Actual) | Interventional | 2017-08-29 | Terminated(stopped due to Lactobacillus reuteri (Gastrus®) was not anymore available in the region) | |||
| Rescue Therapy for Helicobacter Pylori Eradication: A Randomized and Non-inferiority Trail of High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy [NCT04678492] | Phase 4 | 658 participants (Actual) | Interventional | 2020-12-20 | Completed | ||
| Use of APT™ T3X to Decrease the COVID-19 Contamination Rate in Humans [NCT04716426] | 100 participants (Actual) | Interventional | 2021-01-28 | Completed | |||
| Effect of Topical Tetracycline and Dexamethasone on Periodontal and Pulpal Regeneration of Replanted Avulsed Permanent Teeth: A Long-term Follow-up After 9-16 Years [NCT03611920] | 33 participants (Actual) | Observational | 2000-08-14 | Completed | |||
| Rescue Therapy for Helicobacter Pylori Eradication: A Randomized and Non-inferiority Trail of Berberine Plus Amoxicillin Quadruple Therapy Versus Tetracycline Plus Furazolidone Quadruple Therapy [NCT03609892] | Phase 4 | 658 participants (Actual) | Interventional | 2018-08-01 | Completed | ||
| Antibiotic Susceptibility-based Tailored Therapy for Helicobacter Pylori Treatment in Patients With Penicillin Allergy: a Prospective Clinical Trial [NCT03708848] | Phase 4 | 112 participants (Actual) | Interventional | 2018-12-05 | Completed | ||
| Comparison of the Efficacy of 14-day Sequential Therapy and 10-day Bismuth Quadruple Therapy in the Second Line Therapy for Helicobacter Pylori Infection: A Multi-center Randomized Trial [NCT03208426] | Phase 4 | 240 participants (Anticipated) | Interventional | 2017-10-01 | Recruiting | ||
| Assessment of Tetracycline Pleurodesis in Prevention of Primary Spontaneous Pneumothorax Recurrence in Patients With Normal CT-scan [NCT03634605] | 50 participants (Actual) | Interventional | 2015-05-05 | Completed | |||
| Effects of Antimicrobials on the Altered Skin Flora in Patients With Palmar Arsenical Keratosis [NCT03632733] | Phase 2 | 30 participants (Anticipated) | Interventional | 2018-01-21 | Recruiting | ||
| Efficacies of Antimicrobial Susceptibility-Guided Versus Empirical Therapy for Rescue Treatment of Helicobacter Pylori Infection-A Randomized Clinical Trial [NCT03658746] | Phase 4 | 420 participants (Actual) | Interventional | 2019-01-01 | Completed | ||
| Innovative Technology for Assessing the Periodontal Disease and New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin [NCT03656484] | Phase 2 | 50 participants (Actual) | Interventional | 2019-01-15 | Completed | ||
| Bismuth-containing Quadruple Therapy for Helicobacter Pylori First-line Treatment: A Multicenter Randomized Clinical Trial of Different Tetracycline Doses and Frequencies. [NCT05431075] | Phase 4 | 407 participants (Anticipated) | Interventional | 2022-07-31 | Not yet recruiting | ||
| Visiting Staff, Division of Gastroenterology and Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan [NCT04853875] | Phase 4 | 104 participants (Actual) | Interventional | 2021-04-19 | Completed | ||
| [NCT02057926] | Phase 2 | 10 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| Comparison of Genotypic Resistance Guided Versus Susceptibility Testing Guided Therapy for the Third-line Eradication of H. Pylori- a Multicenter Randomized Trial [NCT03555526] | Phase 4 | 320 participants (Anticipated) | Interventional | 2017-12-15 | Recruiting | ||
| Prospective Randomized Study to Compare Clinical Outcomes in Patients With Osteomyelitis Treated With Intravenous Antibiotics Versus Intravenous Antibiotics With an Early Switch to Oral Antibiotics [NCT02099240] | Early Phase 1 | 11 participants (Actual) | Interventional | 2014-03-06 | Terminated(stopped due to Not enough patient enrollment and lack of staffing) | ||
| Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Therapy: A Multicenter Randomized Non-Inferiority Trial of Different Tetracycline Doses and Frequencies. [NCT05432115] | Phase 4 | 407 participants (Anticipated) | Interventional | 2022-06-25 | Recruiting | ||
| A Prospective, Single-center, Randomized, Open-label, Parallel Design Clinical Trial to Compare the 14-day Bismuth Quadruple Therapy and 7-day Culture Based Tailored Therapy for the Eradication of Helicobacter as a Rescue 2nd Therapy. [NCT02359331] | 370 participants (Actual) | Interventional | 2014-08-31 | Terminated | |||
| 10-Day Antimicrobial Susceptibility Testing Guided Triple Therapy Versus 14-Day Empirical Tailored Therapy for the First-line Treatment of Helicobacter Pylori Infection-A Randomized Controlled Trail [NCT03571230] | Phase 4 | 400 participants (Anticipated) | Interventional | 2018-07-01 | Not yet recruiting | ||
| Rescue Therapy for Helicobacter Pylori Eradication: A Randomized Non-Inferiority Trial of Minocycline or Tetracycline in Bismuth Quadruple Therapy [NCT04531059] | Phase 4 | 368 participants (Actual) | Interventional | 2020-10-15 | Completed | ||
| Immunomodulatory and Clinical Effects of Doxycycline on Persistent Symptoms After Treatment of Neuroborreliosis: A Double-blind, Randomised, Crossover Study [NCT01205464] | 15 participants (Actual) | Interventional | 2005-02-28 | Completed | |||
| Prospective, Randomized Controlled Trial Comparing High Dose Amoxicillin Versus Tetracycline Based Quadruple Therapy as Second-line Treatment for Resistant Helicobacter Pylori Infection [NCT02175927] | Phase 4 | 312 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| Comparison Between Tailored Therapy Guided by a Non-invasive Antibiotic Susceptibility Test and Empiric Treatment for First-line Helicobacter Pylori Eradication in Patients With Dyspepsia: a Randomized Controlled Trial. [NCT04107194] | Phase 3 | 362 participants (Anticipated) | Interventional | 2020-01-14 | Recruiting | ||
| Conditioning of Root Surfaces With Citric Acid and Tetracycline for Different Application Times Improves the Outcomes of Root Coverage by Subepithelial Connective Tissue Graft: a Randomized Clinical Trial. [NCT02259543] | 36 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| Efficacy and Safety of a 14-day Modified Sequential Therapy for Refractory Helicobacter Pylori Infection: an Open Randomized Pilot Study [NCT03658733] | Phase 4 | 120 participants (Anticipated) | Interventional | 2018-12-15 | Not yet recruiting | ||
| Efficacy and Safety of a 14-day Modified Sequential Therapy for Refractory Helicobacter Pylori Infection: a Pilot Study [NCT03616405] | Phase 4 | 60 participants (Anticipated) | Interventional | 2019-04-01 | Not yet recruiting | ||
| Efficacies of Tetracycline-levofloxacin Quadruple Therapy, Standard Bismuth Quadruple Therapy and Amoxicillin-levofloxacin Quadruple Therapy in the Second-line Treatment of H Pylori Infection [NCT05850117] | 240 participants (Anticipated) | Interventional | 2020-02-10 | Recruiting | |||
| A Tetracycline Drain Reduces Alveolar Osteitis in Third Molar Surgery [NCT03494972] | 200 participants (Actual) | Interventional | 2016-01-02 | Completed | |||
| Efficacy and Safety of 14-day Concomitant Therapy for Helicobacter Pylori: A Pilot Study [NCT04991584] | 60 participants (Anticipated) | Interventional | 2021-08-04 | Not yet recruiting | |||
| Rifabutin-containing Triple Therapy for Helicobacter Pylori Rescue Treatment: a Randomized Controlled Trial [NCT05874544] | Phase 4 | 357 participants (Anticipated) | Interventional | 2023-05-16 | Recruiting | ||
| A Phase 3b, Comparative and Randomized Study to Assess the Efficacy and Safety of an Intravaginal Ovule Combination of Ketoconazole and Clindamycin Compared With an Intravaginal Cream Combination of Tetracycline and Amphotericin B for the Treatment of Bac [NCT01293643] | Phase 3 | 99 participants (Actual) | Interventional | 2010-05-31 | Completed | ||
| Efficacy and Safety of Quadruple Therapy by Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Given X 10 Days With Omeprazole in Eradication of Helicobacter Pylori: A Comparison to Omeprazole, Amoxicillin and Clarithromycin Given X 7 Days [NCT00669955] | Phase 3 | 440 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| Comparing the Efficacy and Impact on Gastrointestinal Microbiome of Reverse Hybrid Therapy and Bismuth Quadruple Therapy in Helicobacter Pylori Eradication [NCT02547038] | 352 participants (Actual) | Interventional | 2015-02-28 | Completed | |||
| Cognitive Effects of Minocycline in Humans [NCT02193269] | Phase 1 | 10 participants (Actual) | Interventional | 2013-07-08 | Completed | ||
| Efficacy of High-dose Dual Therapy Versus Bismuth-containing Quadruple Therapy for First-line Treatment of Helicobacter Pylori Infection - A Prospective, Randomized, Comparative Study [NCT02483715] | Phase 4 | 589 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| Phase II, Open-label, Single Blind, Randomised Clinical Trial With Tetracycline as a Prophylaxis for Rash and Dermatological Recommendations Versus Dermatological Recommendations in Patients With NSCLC Receiving Treatment With BIBW 2992 [NCT01880515] | Phase 2 | 107 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| Efficacy of 7-day Versus 14-day Bismuth Quadruple Therapy for the Eradication of Helicobacter Pylori : A Multicenter Randomized Non-Inferiority Trial [NCT05997433] | 254 participants (Anticipated) | Interventional | 2023-09-02 | Recruiting | |||
| Evaluation of Root Coverage by Subepithelial Connective Graft Associated to Root Conditioning by Citric Acid Plus Tetracycline and Antimicrobial Photodynamic Therapy: A Randomized Clinical Trial [NCT03095378] | 14 participants (Actual) | Interventional | 2014-03-10 | Completed | |||
| A Clinico-pathological Phase II Study With Translational Elements to Investigate the Possible Infective Causes of Non-Hodgkin Lymphoma of the Ocular Adnexae With Particular Reference to Chlamydia Species and the Effects of MALT Lymphoma Treatment With Tet [NCT01010295] | Phase 2 | 54 participants (Actual) | Interventional | 2006-09-30 | Completed | ||
| T4 - Tetracycline Treatment Tolerability Trial A Pilot Study Examining the Feasibility and Tolerability of Tetracycline Therapy in Post-Treatment Lyme Disease (PTLD) [NCT05219929] | Phase 2 | 60 participants (Anticipated) | Interventional | 2022-11-02 | Enrolling by invitation | ||
| Control of Periodontal Infections [NCT01098448] | Phase 3 | 187 participants (Actual) | Interventional | 1999-09-30 | Completed | ||
| Construction and Application of the Treatment of Refractory Helicobacter Pylori Infection Based on the High-throughput Sequencing Technologies [NCT02741414] | 4,428 participants (Anticipated) | Interventional | 2016-06-30 | Recruiting | |||
| Trial of Antibiotics to Reduce Recurrent Trichiasis (STAR) [NCT00347776] | Phase 4 | 1,452 participants (Actual) | Interventional | 2001-08-31 | Completed | ||
| Efficacy and Safety of 14-day Concomitant Therapy for Helicobacter Pylori: A Pilot Study [NCT03726099] | Phase 4 | 60 participants (Anticipated) | Interventional | 2019-03-15 | Recruiting | ||
| An Open-Label, Randomized, Crossover Study to Evaluate the Pharmacokinetic Interaction After Multiple Oral Doses of Tegoprazan, Metronidazole, Tetracycline and Bismuth in Healthy Volunteers [NCT04066257] | Phase 1 | 32 participants (Actual) | Interventional | 2019-01-17 | Completed | ||
| Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection - A Prospective Randomized, Comparative Study [NCT05332444] | Phase 4 | 450 participants (Anticipated) | Interventional | 2022-04-11 | Recruiting | ||
| Comparison of the Effectiveness of Povidone-Iodine Alone to Povidone-Iodine-Tetracycline Combination for Chemical Pleurodesis in Malignant Pleural Effusion [NCT04039126] | Phase 1 | 62 participants (Anticipated) | Interventional | 2019-06-20 | Recruiting | ||
| Long-Term Bone Quality in Women With Breast Cancer (A Companion Study to S0307) [NCT00873808] | 0 participants (Actual) | Observational | 2008-10-31 | Withdrawn(stopped due to lack of accrual) | |||
| A Topical Antiseptic Bundle for Decreasing Surgical Site Infection in Head and Neck Cancer Patients: Perioperative Effects on the Oral Microbiome [NCT04721626] | 25 participants (Actual) | Observational | 2021-01-06 | Completed | |||
| Bismuth Quadruple Therapy in Helicobacter Pylori Rescue Therapy: A Multicenter Randomized Non-Inferiority Trial of Different Tetracycline Doses and Frequencies. [NCT05802888] | Phase 4 | 260 participants (Anticipated) | Interventional | 2023-03-12 | Recruiting | ||
| Comparison of 7-day and 14-day Bismuth Based Quadruple Therapy for Secondary Helicobacter Pylori Eradication. [NCT00841854] | Phase 4 | 199 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| Phase III, Open Label, Randomized, Multicenter Study to Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin 100mg and Ketoconazole 400mg in Vaginal Capsules, Compared to Combination of Tetracycline 100mg and Amphotericin B 50mg in Vagin [NCT00889356] | Phase 3 | 160 participants (Anticipated) | Interventional | 2009-09-30 | Not yet recruiting | ||
| The Study About the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure [NCT05173493] | 670 participants (Actual) | Observational | 2021-12-30 | Completed | |||
| Rescue Therapy for Helicobacter Pylori Eradication: A Randomized and Non-inferiority Trail of Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy [NCT06168084] | Phase 4 | 688 participants (Anticipated) | Interventional | 2023-06-06 | Recruiting | ||
| Director of Research Division [NCT01863823] | Phase 1/Phase 2 | 350 participants (Actual) | Interventional | 2011-08-31 | Completed | ||
| Bone Disease in Severely Burned Children [NCT00591162] | Phase 2/Phase 3 | 254 participants (Actual) | Interventional | 1992-10-31 | Terminated(stopped due to terminated due to PI lab/duties affected by natural disaster.) | ||
| Efficacy and Safety of 14-day Concomitant Therapy for Difficult-to-Treat Helicobacter Pylori: A Pilot Study [NCT05126121] | 60 participants (Anticipated) | Interventional | 2021-11-20 | Not yet recruiting | |||
| MMP-9 Inhibition for Recalcitrant Wet Age-Related Macular Degeneration (AMD) [NCT04504123] | Phase 2 | 50 participants (Anticipated) | Interventional | 2020-11-04 | Recruiting | ||
| Randomised Double Blind Crossover Placebo Controlled Study to Evaluate the Efficacy of Tetracycline in Epidermolysis Bullosa [NCT00336154] | Phase 4 | 0 participants (Actual) | Interventional | Withdrawn | |||
| [NCT01481844] | Phase 3 | 101 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| Helicobacter Pylori Eradication and Follow-up in Zhongshan Hospital [NCT05061732] | Phase 4 | 4,447 participants (Anticipated) | Interventional | 2021-09-30 | Recruiting | ||
| Rifabutin-containing Triple Therapy for Rescue Treatment of Helicobacter Pylori: A Randomized Clinical Trial [NCT04879992] | 413 participants (Actual) | Interventional | 2021-05-07 | Completed | |||
| CURRENT PRACTICE STUDY OF ANTIBIOTIC TREATMENT OF GASTRIC MALT LYMPHOMA [NCT00002682] | Phase 2 | 5 participants (Actual) | Interventional | 1995-08-10 | Completed | ||
| Sanitation, Water, and Instruction in Face-washing for Trachoma I/II [NCT02754583] | Phase 3 | 340,000 participants (Anticipated) | Interventional | 2015-12-05 | Recruiting | ||
| Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication: A Multicenter Randomized Clinical Trial of 10 and 14 Days [NCT05049902] | Phase 4 | 1,300 participants (Actual) | Interventional | 2021-09-21 | Completed | ||
| An Exploratory, Placebo-Controlled Trial of Prophylactic Tetracycline for Gefitinib-or Cetuximab-Induced Skin Rash (or Other Epidermal Growth Factor Receptor (EGFR) Inhibitor-Induced Skin Rash) [NCT00091247] | 130 participants (Actual) | Interventional | 2004-12-31 | Completed | |||
| The Qure Study: Q-fever Fatigue Syndrome - Response to Treatment [NCT01318356] | Phase 4 | 156 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| Doxycycline-containing Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment: a Randomized Controlled Trial [NCT05874570] | Phase 4 | 368 participants (Anticipated) | Interventional | 2023-06-20 | Recruiting | ||
| Bone Histomorphometry of the Proximal Femur in Denosumab-treated Subjects Undergoing Total Hip Replacement [NCT02576652] | Phase 4 | 6 participants (Actual) | Interventional | 2015-12-22 | Completed | ||
| Predictive Factors Affecting the Efficacy of Local Tetracycline Injection for Treatment of Post-mastectomy Seroma. [NCT04730674] | 18 participants (Actual) | Interventional | 2020-01-01 | Completed | |||
| [NCT01792700] | Phase 4 | 648 participants (Actual) | Interventional | 2003-01-31 | Completed | ||
| Clinical Implication of Next Generation Sequencing of Urinary Bacteria in Patients With Low Colony Forming Units of Bacteria in Traditional Urine Culture [NCT05206500] | Phase 4 | 100 participants (Anticipated) | Interventional | 2022-05-17 | Recruiting | ||
| A Prospective, Multi-center, Randomized, Open-label, Parallel Design Clinical Trial to Compare 10-day Sequential Therapy and 14-day Modified Bismuth Quadruple Therapy for the Eradication of Helicobacter Pylori in Korea [NCT02159976] | 390 participants (Actual) | Interventional | 2014-07-31 | Completed | |||
| Comparison of Hybrid and Bismuth Containing Quadruple Therapies for Helicobacter Pylori Eradication: a Randomized Controlled Trial [NCT02541864] | 330 participants (Actual) | Interventional | 2013-07-31 | Completed | |||
| Comparison of Two Rescue Therapies for Helicobacter Pylori Infection - A Multicenter Randomized Controlled Trial [NCT02547012] | 51 participants (Actual) | Interventional | 2013-11-30 | Completed | |||
| Efficacies of Hybrid, High-dose Dual and Bismuth Quadruple Therapies for the First-line Anti-H Pylori Treatment and Tetracycline-levofloxacin Quadruple Therapy for the Second-line Anti-H Pylori Treatment - a Multicentre Randomized Trial [NCT03779074] | Phase 3 | 918 participants (Actual) | Interventional | 2018-09-03 | Completed | ||
| Clinical Efficacy and Health Economic Evaluation of Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment：Multicenter Randomized Controlled Study [NCT05250050] | Phase 4 | 388 participants (Anticipated) | Interventional | 2022-03-25 | Recruiting | ||
| Helicobacter Pylori Treatment [NCT01668927] | Phase 4 | 424 participants (Actual) | Interventional | 2012-07-31 | Completed | ||
| The Study on the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure [NCT04810793] | 820 participants (Actual) | Observational [Patient Registry] | 2020-07-01 | Completed | |||
| [NCT01742429] | Phase 4 | 200 participants (Actual) | Interventional | 2012-11-30 | Completed | ||
| Standard or Short-course Vonoprazan Non-bismuth Triple Therapy or High-dose Dual Therapy Versus Rabeprazole-bismuth Quadruple Therapy for Primary Helicobacter Pylori Eradication: A Single-center, Randomised, Controlled Trial. [NCT06168214] | Phase 4 | 1,404 participants (Anticipated) | Interventional | 2023-09-04 | Recruiting | ||
| Ten Days Quadruple Versus Sequential Therapy as Empirical First and Second Line Treatment for Helicobacter Pylori Eradication: a Randomized Crossover Trial [NCT01760824] | 391 participants (Actual) | Interventional | 2011-05-31 | Completed | |||
| Intralesional Tetracycline Injection in the Treatment of Chalazia [NCT01763437] | Early Phase 1 | 0 participants (Actual) | Interventional | 2014-03-31 | Withdrawn(stopped due to Investigator left the institution) | ||
| MRI and MRS Diagnosis and Treatment Monitoring of Alzheimer's Disease With Novel Therapy [NCT01463384] | Phase 2 | 13 participants (Actual) | Interventional | 2011-09-30 | Completed | ||
| Efficacy of Two Antimicrobial Susceptibility Testing Guided Antibiotic Selection Strategies in Salvage Helicobacter Pylori Treatment [NCT02988089] | Phase 4 | 480 participants (Anticipated) | Interventional | 2017-04-20 | Recruiting | ||
| A Prospective Randomized Trial of Levofloxacin-amoxicillin Triple Therapy vs. Levofloxacin-tetracycline Quadruple Therapy in Second-line Helicobacter Pylori Treatment [NCT02978157] | 102 participants (Actual) | Interventional | 2015-02-28 | Completed | |||
| A Clinical Study on the Treatment of Paronychia Caused by Afatinib With Zanthoxylum Nitidum Tincture [NCT03908892] | 110 participants (Anticipated) | Interventional | 2019-06-12 | Recruiting | |||
| The Effect of Different Time Intervals on Rescue Treatment of Helicobacter Pylori Infection: a Prospective, Multicenter Observational Study [NCT05620589] | 626 participants (Anticipated) | Observational | 2022-11-11 | Not yet recruiting | |||
| A Phase II Clinical Trial of Anti-Helicobacter Pylori Treatment in Endoscopically Diagnosed Low-Grade Localized Gastric Lymphoma [NCT00003151] | Phase 2 | 96 participants (Anticipated) | Interventional | 1997-09-30 | Completed | ||
| A Prospective Clinical Study Assessing the Effects of Tetracycline Antibiotic on Tear Film and Tear Lipid Composition Within a Population of Patients Diagnosed With Blepharitis and Dry Eye Disease [NCT00355459] | 0 participants (Actual) | Interventional | 2005-08-31 | Withdrawn(stopped due to The PI has elected to terminate study at this time) | |||
| Efficacy and Safety of Helicobacter Pylori Eradication Dual or Triple Regimes Using Vonoprazan as the Antacid [NCT05345210] | Phase 4 | 500 participants (Anticipated) | Interventional | 2022-04-25 | Recruiting | ||
| Phase II, Randomized, Placebo-Controlled, Double-Blind Study of Minocycline in the Treatment of HIV-Associated Cognitive Impairment [NCT00361257] | Phase 2 | 107 participants (Actual) | Interventional | 2007-03-31 | Terminated(stopped due to This study was terminated early due to futility.) | ||
| Efficacies of Two Bismuth Quadruple Therapies in the Second-line Treatment of H Pylori Infection - a Multi-center Randomized Controlled Trial [NCT03779087] | 112 participants (Actual) | Interventional | 2018-07-11 | Completed | |||
| Personalized Treatment for Refractory H Pylori Infection [NCT02547025] | 126 participants (Actual) | Interventional | 2012-08-01 | Completed | |||
| Efficacy of High-dose Dual Therapy Versus Bismuth-containing Quadruple Therapy for Rescue Treatment of Helicobacter Pylori Infection - A Prospective, Randomized, Comparative Study [NCT02490839] | Phase 4 | 450 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| Antimicrobial Susceptibility Testing Guided Triple Therapy in Salvage Helicobacter Pylori Treatment [NCT03139253] | Phase 4 | 120 participants (Anticipated) | Interventional | 2017-05-30 | Not yet recruiting | ||
| Antibiotic Profile of Pathogenic Bacteria Isolated From Postsurgical Site Infections in Public Hospitals in Northern Jordan [NCT05106803] | 24 participants (Actual) | Observational | 2019-08-01 | Completed | |||
| The Efficacy of Minocycline in the Treatment of Angelman Syndrome [NCT01531582] | 25 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| Anabolism Versus Antiresorption: A Quadruple Labeling Histomorphometry Study to Compare the Mechanism of Action of Teriparatide and Denosumab in Postmenopausal Women With Osteoporosis [NCT01753856] | Phase 4 | 69 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication: A Multicenter Randomized Clinical Trial of 10 and 14 Days [NCT04901117] | Phase 4 | 1,300 participants (Anticipated) | Interventional | 2021-06-30 | Not yet recruiting | ||
| Bismuth Quadruple Therapy With Tetracycline Versus Doxycycline as Rescue Therapy for Helicobacter Pylori Infection: a Randomized Controlled Trial [NCT05018923] | Phase 4 | 242 participants (Anticipated) | Interventional | 2021-08-24 | Recruiting | ||
| Helicobacter Pylori and Body Iron in Adults [NCT03146325] | Phase 4 | 0 participants (Actual) | Interventional | 2012-11-30 | Withdrawn(stopped due to Study was not funded and PI has left the institution) | ||
| The Studies of Integrating Gastric and Gut Microbiota, F. Prausnitzii Metabolites, Microenvironment, and Epigenetics to Identify the Cancer Risk of H. Pylori-related Precancerous Conditions Through an AI System and Control the Risky by Probiotic Supplemen [NCT04527055] | Phase 4 | 312 participants (Anticipated) | Interventional | 2020-05-06 | Enrolling by invitation | ||
| The Effects of Minocycline on Opioid-induced Hyperalgesia in Opioid-Maintained Patients [NCT02359006] | 27 participants (Actual) | Interventional | 2015-03-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||