Proteins > Solute carrier family 15 member 2
Page last updated: 2024-08-07 18:44:36
Solute carrier family 15 member 2
A solute carrier family 15 member 2 that is encoded in the genome of rat. [OMA:Q63424, PRO:DNx]
Synonyms
Kidney H(+)/peptide cotransporter;
Oligopeptide transporter, kidney isoform;
Peptide transporter 2
Research
Bioassay Publications (10)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (58)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| aminolevulinic acid | Rattus norvegicus (Norway rat) | Ki | 230.0000 | 1 | 1 |
| glyburide | Rattus norvegicus (Norway rat) | Ki | 7.8000 | 1 | 1 |
| cephaloridine | Rattus norvegicus (Norway rat) | Ki | 8.5000 | 1 | 1 |
| penicillin g | Rattus norvegicus (Norway rat) | Ki | 11,100.0000 | 1 | 1 |
| cephalothin | Rattus norvegicus (Norway rat) | Ki | 8,300.0000 | 1 | 1 |
| cloxacillin | Rattus norvegicus (Norway rat) | Ki | 950.0000 | 1 | 1 |
| oxacillin | Rattus norvegicus (Norway rat) | Ki | 3,300.0000 | 1 | 1 |
| ampicillin | Rattus norvegicus (Norway rat) | Ki | 984.5000 | 2 | 2 |
| aminopenicillanic acid | Rattus norvegicus (Norway rat) | Ki | 19,000.0000 | 1 | 1 |
| glycyl-glycyl-glycine | Rattus norvegicus (Norway rat) | Ki | 160.0000 | 1 | 1 |
| glycylglycine | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 1 |
| dicloxacillin | Rattus norvegicus (Norway rat) | Ki | 420.0000 | 1 | 1 |
| cyclacillin | Rattus norvegicus (Norway rat) | Ki | 35.5000 | 2 | 2 |
| cephalexin | Rattus norvegicus (Norway rat) | Ki | 62.0000 | 2 | 2 |
| cephapirin | Rattus norvegicus (Norway rat) | Ki | 10,000.0000 | 1 | 1 |
| amoxicillin | Rattus norvegicus (Norway rat) | Ki | 304.5000 | 2 | 2 |
| cephradine | Rattus norvegicus (Norway rat) | Ki | 56.0000 | 2 | 2 |
| cefmetazole | Rattus norvegicus (Norway rat) | Ki | 4,300.0000 | 1 | 1 |
| moxalactam | Rattus norvegicus (Norway rat) | Ki | 87.0000 | 1 | 1 |
| cefadroxil anhydrous | Rattus norvegicus (Norway rat) | Ki | 3.0000 | 2 | 2 |
| cefaclor anhydrous | Rattus norvegicus (Norway rat) | Ki | 29.0000 | 1 | 1 |
| omega-aminocaprylic acid | Rattus norvegicus (Norway rat) | Ki | 7,900.0000 | 1 | 1 |
| ubenimex | Rattus norvegicus (Norway rat) | Ki | 18.0000 | 1 | 1 |
| glycyltryptophan | Rattus norvegicus (Norway rat) | Ki | 7.0000 | 1 | 1 |
| glycyltyrosine | Rattus norvegicus (Norway rat) | Ki | 14.0000 | 1 | 1 |
| glycylleucine | Rattus norvegicus (Norway rat) | Ki | 6.0000 | 1 | 1 |
| glycyl-l-phenylalanine | Rattus norvegicus (Norway rat) | Ki | 8.0000 | 1 | 1 |
| glycyl-leucyl-tyrosine | Rattus norvegicus (Norway rat) | Ki | 8.0000 | 1 | 1 |
| glycylaspartic acid | Rattus norvegicus (Norway rat) | Ki | 60.0000 | 1 | 1 |
| beta-aspartylglycine | Rattus norvegicus (Norway rat) | Ki | 28,000.0000 | 1 | 1 |
| lysyllysine | Rattus norvegicus (Norway rat) | Ki | 96.0000 | 1 | 1 |
| alanine-4-nitroanilide | Rattus norvegicus (Norway rat) | Ki | 29.0000 | 1 | 1 |
| aspartylglycine | Rattus norvegicus (Norway rat) | Ki | 46.0000 | 1 | 1 |
| isospaglumic acid | Rattus norvegicus (Norway rat) | IC50 | 3,000.0000 | 1 | 1 |
| carnosine | Rattus norvegicus (Norway rat) | Ki | 66.0000 | 1 | 1 |
| 7-aminocephalosporanic acid | Rattus norvegicus (Norway rat) | Ki | 4,900.0000 | 1 | 1 |
| cefamandole | Rattus norvegicus (Norway rat) | Ki | 2,800.0000 | 1 | 1 |
| aspartyl-aspartic acid | Rattus norvegicus (Norway rat) | Ki | 150.0000 | 1 | 1 |
| cefsulodin | Rattus norvegicus (Norway rat) | Ki | 30,000.0000 | 1 | 1 |
| glycyllysine | Rattus norvegicus (Norway rat) | Ki | 210.0000 | 1 | 1 |
| 7432 s | Rattus norvegicus (Norway rat) | Ki | 666.6667 | 3 | 3 |
| nateglinide | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| cefodizime | Rattus norvegicus (Norway rat) | Ki | 9,000.0000 | 1 | 1 |
| cefixime | Rattus norvegicus (Norway rat) | IC50 | 3,200.0000 | 1 | 1 |
| cefixime | Rattus norvegicus (Norway rat) | Ki | 7,250.0000 | 2 | 2 |
| cefuroxime | Rattus norvegicus (Norway rat) | Ki | 6,301.5000 | 1 | 2 |
| ceftriaxone | Rattus norvegicus (Norway rat) | Ki | 20,000.0000 | 1 | 1 |
| cefepime | Rattus norvegicus (Norway rat) | Ki | 11,400.0000 | 1 | 1 |
| hr 810 | Rattus norvegicus (Norway rat) | Ki | 9,500.0000 | 1 | 1 |
| ceftazidime | Rattus norvegicus (Norway rat) | Ki | 10,000.0000 | 1 | 1 |
| cefotaxime | Rattus norvegicus (Norway rat) | Ki | 20,000.0000 | 1 | 1 |
| prolylglycine | Rattus norvegicus (Norway rat) | Ki | 2,000.0000 | 1 | 1 |
| methampicillin | Rattus norvegicus (Norway rat) | Ki | 730.0000 | 1 | 1 |
| cefdinir | Rattus norvegicus (Norway rat) | IC50 | 10,000.0000 | 1 | 1 |
| cefdinir | Rattus norvegicus (Norway rat) | Ki | 20,100.0000 | 1 | 1 |
| phenylalanylglycine | Rattus norvegicus (Norway rat) | Ki | 7.0000 | 1 | 1 |
| lysylglycine | Rattus norvegicus (Norway rat) | Ki | 21.0000 | 1 | 1 |
| glycylhistidine | Rattus norvegicus (Norway rat) | Ki | 39.0000 | 1 | 1 |
| valacyclovir | Rattus norvegicus (Norway rat) | Ki | 260.0000 | 3 | 3 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| cephalexin | Rattus norvegicus (Norway rat) | Km | 49.0000 | 1 | 1 |
| glycylsarcosine | Rattus norvegicus (Norway rat) | Km | 74.4167 | 6 | 6 |
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, , Volume: 59, Issue:1, 2005
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, , Volume: 59, Issue:1, 2005
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, , Volume: 59, Issue:1, 2005
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Differential recognition of beta -lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2.The Journal of biological chemistry, , Oct-27, Volume: 270, Issue:43, 1995
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, , Volume: 59, Issue:1, 2005
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, , Volume: 59, Issue:1, 2005
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, , Volume: 59, Issue:1, 2005
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Recognition of L-amino acid ester compounds by rat peptide transporters PEPT1 and PEPT2.The Journal of pharmacology and experimental therapeutics, , Volume: 291, Issue:2, 1999
Electrophysiological characteristics of the proton-coupled peptide transporter PEPT2 cloned from rat brain.The American journal of physiology, , Volume: 275, Issue:4, 1998
Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.Biochemical and biophysical research communications, , May-19, Volume: 246, Issue:2, 1998
Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2.Biochimica et biophysica acta, , Mar-13, Volume: 1324, Issue:2, 1997
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, , Volume: 59, Issue:1, 2005
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2.Biochimica et biophysica acta, , Mar-13, Volume: 1324, Issue:2, 1997
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, , Volume: 59, Issue:1, 2005
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2.Biochimica et biophysica acta, , Mar-13, Volume: 1324, Issue:2, 1997
Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells.The American journal of physiology, , Volume: 273, Issue:5, 1997
Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2.Biochimica et biophysica acta, , Mar-13, Volume: 1324, Issue:2, 1997