Condition | Indicated | Relationship Strength | Studies | Trials |
Innate Inflammatory Response [description not available] | 0 | 15.06 | 163 | 4 |
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 15.06 | 163 | 4 |
Primary Peritonitis [description not available] | 0 | 5.1 | 16 | 0 |
Peritonitis INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs. | 0 | 10.1 | 16 | 0 |
Encephalitis, Polio [description not available] | 0 | 2.06 | 1 | 0 |
Poliomyelitis An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5) | 0 | 2.06 | 1 | 0 |
Congenital Zika Syndrome [description not available] | 0 | 2.25 | 1 | 0 |
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 8.9 | 64 | 0 |
Zika Virus Infection A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME. | 0 | 2.25 | 1 | 0 |
Edema-Proteinuria-Hypertension Gestosis [description not available] | 0 | 5.39 | 12 | 1 |
Pre-Eclampsia A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease. | 0 | 5.39 | 12 | 1 |
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 12.71 | 32 | 1 |
Airway Remodeling The structural changes in the number, mass, size and/or composition of the airway tissues. | 0 | 7.89 | 3 | 0 |
Benign Neoplasms [description not available] | 0 | 5.18 | 13 | 0 |
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 5.18 | 13 | 0 |
Infections, Plasmodium [description not available] | 0 | 2.31 | 1 | 0 |
Malaria A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. | 0 | 2.31 | 1 | 0 |
Elevated Cholesterol [description not available] | 0 | 2.52 | 2 | 0 |
Blood Pressure, High [description not available] | 0 | 3.57 | 2 | 0 |
Hypercholesterolemia A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population. | 0 | 2.52 | 2 | 0 |
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 3.57 | 2 | 0 |
2019 Novel Coronavirus Disease [description not available] | 0 | 6 | 4 | 1 |
Atherogenesis [description not available] | 0 | 3.21 | 5 | 0 |
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 8.21 | 5 | 0 |
Cancer of Prostate [description not available] | 0 | 2.41 | 1 | 0 |
Prostatic Neoplasms Tumors or cancer of the PROSTATE. | 0 | 2.41 | 1 | 0 |
Inflammation, Endodontic [description not available] | 0 | 2.41 | 1 | 0 |
Pulpitis Inflammation of the DENTAL PULP, usually due to bacterial infection in dental caries, tooth fracture, or other conditions causing exposure of the pulp to bacterial invasion. Chemical irritants, thermal factors, hyperemic changes, and other factors may also cause pulpitis. | 0 | 7.41 | 1 | 0 |
Chronic Lung Injury [description not available] | 0 | 3.73 | 9 | 0 |
Acute Respiratory Distress Syndrome [description not available] | 0 | 2.91 | 3 | 0 |
Respiratory Distress Syndrome A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA. | 0 | 2.91 | 3 | 0 |
Alloxan Diabetes [description not available] | 0 | 3.69 | 8 | 0 |
Acute Brain Injuries [description not available] | 0 | 2.88 | 3 | 0 |
Brain Hemorrhage, Cerebral [description not available] | 0 | 2.41 | 1 | 0 |
Brain Injuries Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits. | 0 | 2.88 | 3 | 0 |
Cerebral Hemorrhage Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA. | 0 | 7.41 | 1 | 0 |
Atrophy, Muscle [description not available] | 0 | 2.6 | 1 | 0 |
Muscular Atrophy Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation. | 0 | 2.6 | 1 | 0 |
Lung Injury, Acute [description not available] | 0 | 4.39 | 18 | 0 |
Acute Edematous Pancreatitis [description not available] | 0 | 5.68 | 9 | 2 |
Acute Disease Disease having a short and relatively severe course. | 0 | 7.93 | 17 | 1 |
Pancreatitis INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. | 0 | 5.68 | 9 | 2 |
Acute Lung Injury A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). | 0 | 4.39 | 18 | 0 |
Cognitive Decline [description not available] | 0 | 4.03 | 4 | 0 |
Acute Confusional Senile Dementia [description not available] | 0 | 4.14 | 13 | 0 |
Alzheimer Disease A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 9.14 | 13 | 0 |
Cognitive Dysfunction Diminished or impaired mental and/or intellectual function. | 0 | 4.03 | 4 | 0 |
Endometrioma An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst. | 0 | 6.36 | 23 | 0 |
Endometriosis A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum. | 0 | 6.36 | 23 | 0 |
Arthritis, Degenerative [description not available] | 0 | 4.22 | 13 | 0 |
Osteoarthritis A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | 0 | 9.22 | 13 | 0 |
Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. | 0 | 4.94 | 6 | 1 |
Cardiovascular Stroke [description not available] | 0 | 4.29 | 6 | 0 |
Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 9.29 | 6 | 0 |
Gout Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi. | 0 | 2.41 | 1 | 0 |
Diabetes Mellitus, Adult-Onset [description not available] | 0 | 6.7 | 11 | 1 |
Diabetes Mellitus, Type 2 A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 6.7 | 11 | 1 |
Cirrhosis [description not available] | 0 | 3.49 | 7 | 0 |
Fibrosis Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. | 0 | 8.49 | 7 | 0 |
Asthma, Bronchial [description not available] | 0 | 10.87 | 39 | 3 |
Delayed Effects, Prenatal Exposure [description not available] | 0 | 2.6 | 1 | 0 |
Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). | 0 | 10.87 | 39 | 3 |
Burns, Chemical Burns caused by contact with or exposure to CAUSTICS or strong ACIDS. | 0 | 2.6 | 1 | 0 |
Leukoma [description not available] | 0 | 2.6 | 1 | 0 |
Angiogenesis, Pathologic [description not available] | 0 | 5.32 | 12 | 0 |
Hyphema Bleeding in the anterior chamber of the eye. | 0 | 2.6 | 1 | 0 |
Corneal Opacity Disorder occurring in the central or peripheral area of the cornea. The usual degree of transparency becomes relatively opaque. | 0 | 2.6 | 1 | 0 |
Clerambault Syndrome [description not available] | 0 | 2.6 | 1 | 0 |
Cirrhosis, Liver [description not available] | 0 | 2.45 | 2 | 0 |
Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 2.45 | 2 | 0 |
DDPAC [description not available] | 0 | 2.21 | 1 | 0 |
Frontotemporal Dementia The most common clinical form of FRONTOTEMPORAL LOBAR DEGENERATION, this dementia presents with personality and behavioral changes often associated with disinhibition, apathy, and lack of insight. | 0 | 2.21 | 1 | 0 |
Pericementitis [description not available] | 0 | 6.4 | 8 | 0 |
Periodontitis Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) | 0 | 11.4 | 8 | 0 |
Adenoma, beta-Cell [description not available] | 0 | 2.58 | 2 | 0 |
Cancer of Pancreas [description not available] | 0 | 3.08 | 4 | 0 |
Insulinoma A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA. | 0 | 2.58 | 2 | 0 |
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 3.08 | 4 | 0 |
Injuries, Spinal Cord [description not available] | 0 | 2.87 | 3 | 0 |
Spinal Cord Injuries Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.). | 0 | 2.87 | 3 | 0 |
Bronchial Hyperreactivity Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory. | 0 | 3.13 | 5 | 0 |
Gastric Ulcer [description not available] | 0 | 2.47 | 2 | 0 |
Stomach Ulcer Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS). | 0 | 2.47 | 2 | 0 |
Autoimmune Disease [description not available] | 0 | 3.77 | 3 | 0 |
Autoimmune Diseases Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. | 0 | 3.77 | 3 | 0 |
Uveitis Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed) | 0 | 3.42 | 2 | 0 |
Experimental Lung Inflammation Inflammation of any part, segment or lobe, of the lung parenchyma. | 0 | 3.9 | 11 | 0 |
Airway Hyper-Responsiveness [description not available] | 0 | 2.79 | 3 | 0 |
Pneumonia Infection of the lung often accompanied by inflammation. | 0 | 3.9 | 11 | 0 |
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 4.21 | 3 | 1 |
Disease Exacerbation [description not available] | 0 | 4.97 | 13 | 0 |
Fatty Liver, Nonalcoholic [description not available] | 0 | 2.25 | 1 | 0 |
Non-alcoholic Fatty Liver Disease Fatty liver finding without excessive ALCOHOL CONSUMPTION. | 0 | 2.25 | 1 | 0 |
Fetal Growth Restriction [description not available] | 0 | 8.75 | 3 | 0 |
Labor, Premature [description not available] | 0 | 3.48 | 2 | 0 |
Fetal Growth Retardation Failure of a FETUS to attain expected GROWTH. | 0 | 3.75 | 3 | 0 |
Apoplexy [description not available] | 0 | 4.45 | 4 | 1 |
Stroke A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810) | 0 | 4.45 | 4 | 1 |
Arthritides, Bacterial [description not available] | 0 | 2.25 | 1 | 0 |
Infections, Staphylococcal [description not available] | 0 | 2.25 | 1 | 0 |
Staphylococcal Infections Infections with bacteria of the genus STAPHYLOCOCCUS. | 0 | 2.25 | 1 | 0 |
Alveolitis, Fibrosing [description not available] | 0 | 2.51 | 2 | 0 |
Pulmonary Fibrosis A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death. | 0 | 7.51 | 2 | 0 |
Rheumatoid Arthritis [description not available] | 0 | 9.81 | 7 | 0 |
Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. | 0 | 4.81 | 7 | 0 |
Chronic Kidney Diseases [description not available] | 0 | 3.98 | 2 | 1 |
Renal Insufficiency, Chronic Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002) | 0 | 3.98 | 2 | 1 |
Anoxia-Ischemia, Brain [description not available] | 0 | 2.25 | 1 | 0 |
Anoxemia [description not available] | 0 | 2.54 | 2 | 0 |
Brain Swelling [description not available] | 0 | 3.23 | 5 | 0 |
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms. | 0 | 7.54 | 2 | 0 |
Brain Edema Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6) | 0 | 3.23 | 5 | 0 |
Hypoxia-Ischemia, Brain A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions. | 0 | 2.25 | 1 | 0 |
Adjuvant Arthritis [description not available] | 0 | 3.2 | 5 | 0 |
Left Ventricular Dysfunction [description not available] | 0 | 2.31 | 1 | 0 |
Angor Pectoris [description not available] | 0 | 2.31 | 1 | 0 |
Arteriosclerosis, Coronary [description not available] | 0 | 2.31 | 1 | 0 |
Cardiac Failure [description not available] | 0 | 2.57 | 2 | 0 |
Angina Pectoris The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION. | 0 | 2.31 | 1 | 0 |
Coronary Artery Disease Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause. | 0 | 2.31 | 1 | 0 |
Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. | 0 | 2.57 | 2 | 0 |
Ventricular Dysfunction, Left A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall. | 0 | 2.31 | 1 | 0 |
Cytokine Release Syndrome A severe immune reaction characterized by excessive release of CYTOKINES. Symptoms include DYSPNEA; FEVER; HEADACHE; HYPOTENSION; NAUSEA; RASH; TACHYCARDIA; HYPOXIA; HYPERFERRITINEMIA, and MULTIPLE ORGAN FAILURE. It is associated with viral infections, SEPSIS; AUTOIMMUNE DISEASES and a variety of factors used in IMMUNOTHERAPY. | 0 | 3.23 | 1 | 0 |
Edema, Pulmonary [description not available] | 0 | 2.31 | 1 | 0 |
Pulmonary Edema Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening. | 0 | 2.31 | 1 | 0 |
Pneumonia, Pneumococcal A febrile disease caused by STREPTOCOCCUS PNEUMONIAE. | 0 | 2.31 | 1 | 0 |
Allergic Encephalomyelitis [description not available] | 0 | 2.31 | 1 | 0 |
MS (Multiple Sclerosis) [description not available] | 0 | 2.31 | 1 | 0 |
Multiple Sclerosis An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) | 0 | 2.31 | 1 | 0 |
Cornea Injuries [description not available] | 0 | 2.31 | 1 | 0 |
Corneal Injuries Damage or trauma inflicted to the CORNEA by external means. | 0 | 2.31 | 1 | 0 |
Aspergillus Infection [description not available] | 0 | 2.72 | 2 | 0 |
Eye Infections, Fungal Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses. | 0 | 2.31 | 1 | 0 |
Aspergillosis Infections with fungi of the genus ASPERGILLUS. | 0 | 2.72 | 2 | 0 |
Keratitis Inflammation of the cornea. | 0 | 7.5 | 2 | 0 |
Complication, Postoperative [description not available] | 0 | 5.33 | 2 | 1 |
Segond Fracture [description not available] | 0 | 3.06 | 1 | 0 |
Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. | 0 | 5.33 | 2 | 1 |
Tibial Fractures Fractures of the TIBIA. | 0 | 3.06 | 1 | 0 |
Carditis [description not available] | 0 | 7.15 | 1 | 0 |
Myocarditis Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies. | 0 | 7.15 | 1 | 0 |
Cerebral Infarction, Middle Cerebral Artery [description not available] | 0 | 2.78 | 3 | 0 |
Infarction, Middle Cerebral Artery NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction. | 0 | 2.78 | 3 | 0 |
Ovarian Diseases Pathological processes of the OVARY. | 0 | 2.17 | 1 | 0 |
Hypermobility, Joint [description not available] | 0 | 2.15 | 1 | 0 |
Bucket Handle Tears [description not available] | 0 | 2.15 | 1 | 0 |
Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 7.99 | 4 | 0 |
Skin Ulcer An ULCER of the skin and underlying tissues. | 0 | 7.15 | 1 | 0 |
Palmoplantaris Pustulosis [description not available] | 0 | 2.5 | 2 | 0 |
Psoriasis A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis. | 0 | 7.5 | 2 | 0 |
Cancer of Liver [description not available] | 0 | 5.46 | 5 | 1 |
Colorectal Cancer [description not available] | 0 | 5.12 | 3 | 1 |
Liver Neoplasms Tumors or cancer of the LIVER. | 0 | 5.46 | 5 | 1 |
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 5.12 | 3 | 1 |
Cerebral Ischemia [description not available] | 0 | 3.36 | 6 | 0 |
Injury, Ischemia-Reperfusion [description not available] | 0 | 4.09 | 14 | 0 |
Brain Ischemia Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. | 0 | 3.36 | 6 | 0 |
Reperfusion Injury Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 4.09 | 14 | 0 |
Chronic Illness [description not available] | 0 | 3.69 | 9 | 0 |
Tendinitis Inflammation of TENDONS. It is characterized by the degeneration of tendons accompanied by an inflammatory repair response, fibroblastic proliferation, and formation of granulation tissue. Tendinitis is not a clinical diagnosis and can be confirmed only by histopathological findings. | 0 | 2.8 | 3 | 0 |
Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 3.69 | 9 | 0 |
Tendinopathy Clinical syndrome describing overuse tendon injuries characterized by a combination of PAIN, diffuse or localized swelling, and impaired performance. | 0 | 2.8 | 3 | 0 |
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 4.31 | 4 | 1 |
Infections, Pseudomonas [description not available] | 0 | 3.06 | 4 | 0 |
Pseudomonas Infections Infections with bacteria of the genus PSEUDOMONAS. | 0 | 3.06 | 4 | 0 |
Retinal Diseases Diseases involving the RETINA. | 0 | 2.15 | 1 | 0 |
Leishmaniasis, American [description not available] | 0 | 2.15 | 1 | 0 |
Leishmaniasis, Cutaneous An endemic disease that is characterized by the development of single or multiple localized lesions on exposed areas of skin that typically ulcerate. The disease has been divided into Old and New World forms. Old World leishmaniasis is separated into three distinct types according to epidemiology and clinical manifestations and is caused by species of the L. tropica and L. aethiopica complexes as well as by species of the L. major genus. New World leishmaniasis, also called American leishmaniasis, occurs in South and Central America and is caused by species of the L. mexicana or L. braziliensis complexes. | 0 | 2.15 | 1 | 0 |
Invasiveness, Neoplasm [description not available] | 0 | 2.54 | 2 | 0 |
Kidney Diseases Pathological processes of the KIDNEY or its component tissues. | 0 | 3.71 | 3 | 0 |
Obesity A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 5.45 | 8 | 0 |
Bleb [description not available] | 0 | 4.8 | 2 | 1 |
Hepatocellular Carcinoma [description not available] | 0 | 7.95 | 4 | 0 |
Metastase [description not available] | 0 | 2.59 | 2 | 0 |
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 2.95 | 4 | 0 |
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 2.59 | 2 | 0 |
Blood Poisoning [description not available] | 0 | 3.98 | 12 | 0 |
Sepsis Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 3.98 | 12 | 0 |
Injuries Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used. | 0 | 2.17 | 1 | 0 |
Wounds and Injuries Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. | 0 | 2.17 | 1 | 0 |
Brain Inflammation [description not available] | 0 | 2.5 | 2 | 0 |
Aura [description not available] | 0 | 2.17 | 1 | 0 |
Encephalitis Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition. | 0 | 2.5 | 2 | 0 |
Epilepsy A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) | 0 | 2.17 | 1 | 0 |
Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. | 0 | 5.16 | 11 | 0 |
Embolism, Fat Blocking of a blood vessel by fat deposits in the circulation. It is often seen after fractures of large bones or after administration of CORTICOSTEROIDS. | 0 | 2.21 | 1 | 0 |
Sterility, Female [description not available] | 0 | 3.45 | 2 | 0 |
Infertility, Female Diminished or absent ability of a female to achieve conception. | 0 | 3.45 | 2 | 0 |
Hemorrhage, Subarachnoid [description not available] | 0 | 2.57 | 2 | 0 |
Subarachnoid Hemorrhage Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status. | 0 | 7.57 | 2 | 0 |
Hives [description not available] | 0 | 2.17 | 1 | 0 |
Urticaria A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress. | 0 | 7.17 | 1 | 0 |
Diabetic Glomerulosclerosis [description not available] | 0 | 2.21 | 1 | 0 |
Diabetic Nephropathies KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE. | 0 | 2.21 | 1 | 0 |
Deep Vein Thrombosis [description not available] | 0 | 2.21 | 1 | 0 |
Venous Thrombosis The formation or presence of a blood clot (THROMBUS) within a vein. | 0 | 2.21 | 1 | 0 |
Apnea, Obstructive Sleep [description not available] | 0 | 2.21 | 1 | 0 |
Sleep Apnea, Obstructive A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395) | 0 | 2.21 | 1 | 0 |
Hyperoxia An abnormal increase in the amount of oxygen in the tissues and organs. | 0 | 2.54 | 2 | 0 |
Retinal Degeneration A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304) | 0 | 7.21 | 1 | 0 |
Hyperglycemia, Postprandial Abnormally high BLOOD GLUCOSE level after a meal. | 0 | 3.12 | 1 | 0 |
Hyperglycemia Abnormally high BLOOD GLUCOSE level. | 0 | 3.12 | 1 | 0 |
Koch's Disease [description not available] | 0 | 4.07 | 5 | 0 |
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 3.69 | 3 | 0 |
Tuberculosis Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS. | 0 | 4.07 | 5 | 0 |
Peritoneal Diseases Pathological processes involving the PERITONEUM. | 0 | 2.08 | 1 | 0 |
Injury, Myocardial Reperfusion [description not available] | 0 | 4.39 | 7 | 0 |
Cerebral Malaria [description not available] | 0 | 2.5 | 2 | 0 |
American Trypanosomiasis [description not available] | 0 | 2.5 | 2 | 0 |
Chagas Disease Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON. | 0 | 2.5 | 2 | 0 |
Coronary Heart Disease [description not available] | 0 | 7.42 | 2 | 0 |
Anxiety Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS. | 0 | 7.49 | 2 | 0 |
Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 2.42 | 2 | 0 |
Cancer of Stomach [description not available] | 0 | 2.08 | 1 | 0 |
Stomach Neoplasms Tumors or cancer of the STOMACH. | 0 | 2.08 | 1 | 0 |
Abortion, Tubal [description not available] | 0 | 2.08 | 1 | 0 |
Abortion, Spontaneous Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference. | 0 | 2.08 | 1 | 0 |
Cystic Fibrosis of Pancreas [description not available] | 0 | 6.91 | 9 | 1 |
Cystic Fibrosis An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION. | 0 | 6.91 | 9 | 1 |
Diffuse Parenchymal Lung Disease [description not available] | 0 | 3 | 1 | 0 |
Lung Diseases, Interstitial A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features. | 0 | 3 | 1 | 0 |
Infections, Klebsiella [description not available] | 0 | 2.08 | 1 | 0 |
Klebsiella Infections Infections with bacteria of the genus KLEBSIELLA. | 0 | 2.08 | 1 | 0 |
Acute Liver Injury, Drug-Induced [description not available] | 0 | 2.45 | 2 | 0 |
Chemical and Drug Induced Liver Injury A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 2.45 | 2 | 0 |
Arrhythmia [description not available] | 0 | 2.48 | 2 | 0 |
Arrhythmias, Cardiac Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. | 0 | 2.48 | 2 | 0 |
Nerve Pain [description not available] | 0 | 3.19 | 5 | 0 |
Neuralgia Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve. | 0 | 3.19 | 5 | 0 |
Anasarca [description not available] | 0 | 3.29 | 6 | 0 |
Allergic Reaction [description not available] | 0 | 3.88 | 4 | 0 |
Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. | 0 | 3.29 | 6 | 0 |
Hypersensitivity Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen. | 0 | 8.88 | 4 | 0 |
Cancer of Lung [description not available] | 0 | 2.08 | 1 | 0 |
Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 2.08 | 1 | 0 |
Nasal Catarrh [description not available] | 0 | 2.08 | 1 | 0 |
Sinus Infections [description not available] | 0 | 2.08 | 1 | 0 |
Nasal Polyps Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations. | 0 | 2.69 | 3 | 0 |
Rhinitis Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES. | 0 | 2.08 | 1 | 0 |
Sinusitis Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES. | 0 | 2.08 | 1 | 0 |
Lymphangiomyomatosis [description not available] | 0 | 2.1 | 1 | 0 |
Carcinogenesis The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. | 0 | 2.1 | 1 | 0 |
Lymphangioleiomyomatosis A disease characterized by the progressive invasion of SMOOTH MUSCLE CELLS into the LYMPHATIC VESSELS, and the BLOOD VESSELS. The majority of the cases occur in the LUNGS of women of child-bearing age, eventually blocking the flow of air, blood, and lymph. The common symptom is shortness of breath (DYSPNEA). | 0 | 2.1 | 1 | 0 |
E coli Infections [description not available] | 0 | 2.5 | 2 | 0 |
Escherichia coli Infections Infections with bacteria of the species ESCHERICHIA COLI. | 0 | 2.5 | 2 | 0 |
Colitis Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER. | 0 | 2.75 | 3 | 0 |
Breathing Sounds [description not available] | 0 | 2.1 | 1 | 0 |
Respiratory Sounds Noises, normal and abnormal, heard on auscultation over any part of the RESPIRATORY TRACT. | 0 | 2.1 | 1 | 0 |
Thrombopenia [description not available] | 0 | 2.1 | 1 | 0 |
Thrombocytopenia A subnormal level of BLOOD PLATELETS. | 0 | 2.1 | 1 | 0 |
Cardiovascular Diseases Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 4.82 | 4 | 0 |
Disease, Pulmonary [description not available] | 0 | 3.41 | 7 | 0 |
Lung Diseases Pathological processes involving any part of the LUNG. | 0 | 3.41 | 7 | 0 |
Adenocarcinoma, Basal Cell [description not available] | 0 | 2.1 | 1 | 0 |
Barrett Epithelium [description not available] | 0 | 2.1 | 1 | 0 |
Cancer of Esophagus [description not available] | 0 | 2.1 | 1 | 0 |
Esophageal Reflux [description not available] | 0 | 2.1 | 1 | 0 |
Experimental Neoplasms [description not available] | 0 | 2.48 | 2 | 0 |
Adenocarcinoma A malignant epithelial tumor with a glandular organization. | 0 | 2.1 | 1 | 0 |
Barrett Esophagus A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus. | 0 | 2.1 | 1 | 0 |
Esophageal Neoplasms Tumors or cancer of the ESOPHAGUS. | 0 | 2.1 | 1 | 0 |
Gastroesophageal Reflux Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER. | 0 | 2.1 | 1 | 0 |
Constriction, Pathological [description not available] | 0 | 2.1 | 1 | 0 |
Allodynia [description not available] | 0 | 7.98 | 4 | 0 |
Constriction, Pathologic The condition of an anatomical structure's being constricted beyond normal dimensions. | 0 | 2.1 | 1 | 0 |
Hypertrophy General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA). | 0 | 2.1 | 1 | 0 |
Spermatic Cord Torsion The twisting of the SPERMATIC CORD due to an anatomical abnormality that left the TESTIS mobile and dangling in the SCROTUM. The initial effect of testicular torsion is obstruction of venous return. Depending on the duration and degree of cord rotation, testicular symptoms range from EDEMA to interrupted arterial flow and testicular pain. If blood flow to testis is absent for 4 to 6 h, SPERMATOGENESIS may be permanently lost. | 0 | 2.1 | 1 | 0 |
Allergic Contact Dermatitis [description not available] | 0 | 3.01 | 1 | 0 |
Eczema, Atopic [description not available] | 0 | 3.01 | 1 | 0 |
Dermatitis, Atopic A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. | 0 | 3.01 | 1 | 0 |
Dermatitis, Allergic Contact A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure. | 0 | 3.01 | 1 | 0 |
Acute Hemolytic Transfusion Reaction [description not available] | 0 | 2.1 | 1 | 0 |
Transfusion Reaction Complications of BLOOD TRANSFUSION. Included adverse reactions are common allergic and febrile reactions; hemolytic (delayed and acute) reactions; and other non-hemolytic adverse reactions such as infections and adverse immune reactions related to immunocompatibility. | 0 | 2.1 | 1 | 0 |
Central Nervous System Disease [description not available] | 0 | 3.01 | 1 | 0 |
Central Nervous System Diseases Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord. | 0 | 3.01 | 1 | 0 |
Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. | 0 | 2.11 | 1 | 0 |
Hyperplasia An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. | 0 | 2.48 | 2 | 0 |
Bacteremia The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion. | 0 | 2.52 | 2 | 0 |
Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 2.1 | 1 | 0 |
Complications, Infectious Pregnancy [description not available] | 0 | 2.11 | 1 | 0 |
Brucella Infection [description not available] | 0 | 2.11 | 1 | 0 |
Brucellosis Infection caused by bacteria of the genus BRUCELLA mainly involving the MONONUCLEAR PHAGOCYTE SYSTEM. This condition is characterized by fever, weakness, malaise, and weight loss. | 0 | 2.11 | 1 | 0 |
Autism Spectrum Disorder Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V) | 0 | 7.11 | 1 | 0 |
Kaposi Sarcoma [description not available] | 0 | 2.52 | 2 | 0 |
Sarcoma, Kaposi A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause. | 0 | 2.52 | 2 | 0 |
Degenerative Disc Disease [description not available] | 0 | 2.11 | 1 | 0 |
Disc, Herniated [description not available] | 0 | 2.11 | 1 | 0 |
Intervertebral Disc Displacement An INTERVERTEBRAL DISC in which the NUCLEUS PULPOSUS has protruded through surrounding ANNULUS FIBROSUS. This occurs most frequently in the lower lumbar region. | 0 | 2.11 | 1 | 0 |
Intervertebral Disc Degeneration Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates. | 0 | 2.11 | 1 | 0 |
Experimental Hepatoma [description not available] | 0 | 2.11 | 1 | 0 |
B16 Melanoma [description not available] | 0 | 2.11 | 1 | 0 |
Diabetic Retinopathy Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. | 0 | 3.91 | 4 | 0 |
C gattii Infection [description not available] | 0 | 2.13 | 1 | 0 |
Fungal Lung Diseases [description not available] | 0 | 2.13 | 1 | 0 |
Cryptococcosis Fungal infection caused by genus CRYPTOCOCCUS. | 0 | 2.13 | 1 | 0 |
Liver Dysfunction [description not available] | 0 | 3.69 | 3 | 0 |
Liver Diseases Pathological processes of the LIVER. | 0 | 3.69 | 3 | 0 |
Cryptogenic Fibrosing Alveolitis [description not available] | 0 | 2.11 | 1 | 0 |
Idiopathic Pulmonary Fibrosis A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change. | 0 | 2.11 | 1 | 0 |
Dry Eye [description not available] | 0 | 2.11 | 1 | 0 |
Dry Eye Syndromes Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. | 0 | 2.11 | 1 | 0 |
Genetic Predisposition [description not available] | 0 | 3.03 | 1 | 0 |
Parodontosis [description not available] | 0 | 2.75 | 3 | 0 |
Periodontal Diseases Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT. | 0 | 7.75 | 3 | 0 |
Latent Tuberculosis The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test. | 0 | 2.11 | 1 | 0 |
Infections, Mycobacterium [description not available] | 0 | 2.13 | 1 | 0 |
Mycobacterium Infections Infections with bacteria of the genus MYCOBACTERIUM. | 0 | 2.13 | 1 | 0 |
Cardiometabolic Syndrome A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components not only include metabolic dysfunctions of METABOLIC SYNDROME but also HYPERTENSION, and ABDOMINAL OBESITY. | 0 | 4.63 | 3 | 0 |
Metabolic Syndrome A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. | 0 | 9.63 | 3 | 0 |
Hepatitis INFLAMMATION of the LIVER. | 0 | 2.13 | 1 | 0 |
Blastomyces brasiliensis Infection [description not available] | 0 | 2.11 | 1 | 0 |
Autism [description not available] | 0 | 3.04 | 1 | 0 |
Autistic Disorder A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V) | 0 | 3.04 | 1 | 0 |
Bowel Diseases, Inflammatory [description not available] | 0 | 4.84 | 5 | 0 |
Inflammatory Bowel Diseases Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS. | 0 | 4.84 | 5 | 0 |
Acute Hepatic Failure [description not available] | 0 | 2.13 | 1 | 0 |
Liver Failure, Acute A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C. | 0 | 2.13 | 1 | 0 |
Hyperhomocysteinemia Condition in which the plasma levels of homocysteine and related metabolites are elevated ( | 0 | 2.13 | 1 | 0 |
Liver Steatosis [description not available] | 0 | 2.13 | 1 | 0 |
Fatty Liver Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS. | 0 | 2.13 | 1 | 0 |
Bronchospasm, Exercise-Induced [description not available] | 0 | 2.48 | 2 | 0 |
Asthma, Exercise-Induced Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it). | 0 | 2.48 | 2 | 0 |
Asialia [description not available] | 0 | 2.13 | 1 | 0 |
Xerostomia Decreased salivary flow. | 0 | 2.13 | 1 | 0 |
Adult Periodontitis [description not available] | 0 | 2.15 | 1 | 0 |
Carcinoma 256, Walker A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed) | 0 | 2.13 | 1 | 0 |
Insulin Sensitivity [description not available] | 0 | 2.5 | 2 | 0 |
Insulin Resistance Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. | 0 | 2.5 | 2 | 0 |
Insect Bites [description not available] | 0 | 2.13 | 1 | 0 |
Insect Bites and Stings Bites and stings inflicted by insects. | 0 | 2.13 | 1 | 0 |
Malignant Melanoma [description not available] | 0 | 2.15 | 1 | 0 |
Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) | 0 | 2.15 | 1 | 0 |
Diathesis [description not available] | 0 | 2.96 | 4 | 0 |
Infections, Respiratory [description not available] | 0 | 2.15 | 1 | 0 |
Francisella tularensis Infection [description not available] | 0 | 2.15 | 1 | 0 |
Respiratory Tract Infections Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases. | 0 | 2.15 | 1 | 0 |
Tularemia A plague-like disease of rodents, transmissible to man. It is caused by FRANCISELLA TULARENSIS and is characterized by fever, chills, headache, backache, and weakness. | 0 | 7.15 | 1 | 0 |
Lymphoma, Primary Effusion A rare neoplasm of large B-cells usually presenting as serious effusions without detectable tumor masses. The most common sites of involvement are the pleural, pericardial, and peritoneal cavities. It is associated with HUMAN HERPESVIRUS 8, most often occurring in the setting of immunodeficiency. | 0 | 2.13 | 1 | 0 |
Inborn Errors of Metabolism [description not available] | 0 | 2.13 | 1 | 0 |
Metabolism, Inborn Errors Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero. | 0 | 2.13 | 1 | 0 |
Infant, Small for Gestational Age An infant having a birth weight lower than expected for its gestational age. | 0 | 2.15 | 1 | 0 |
Autoimmune Diabetes [description not available] | 0 | 2.55 | 2 | 0 |
Diabetes Mellitus, Type 1 A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. | 0 | 2.55 | 2 | 0 |
Parasitemia The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed) | 0 | 2.51 | 2 | 0 |
Cardiomyopathy, Chagas [description not available] | 0 | 2.51 | 2 | 0 |
Chagas Cardiomyopathy A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY. | 0 | 7.51 | 2 | 0 |
Bone Loss, Osteoclastic [description not available] | 0 | 2.15 | 1 | 0 |
Bone Loss, Perimenopausal [description not available] | 0 | 3.38 | 2 | 0 |
Osteoporosis, Postmenopausal Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency. | 0 | 3.38 | 2 | 0 |
Abdominal Aortic Aneurysm [description not available] | 0 | 3.06 | 1 | 0 |
Aortic Aneurysm, Abdominal An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm. | 0 | 3.06 | 1 | 0 |
Angiitis [description not available] | 0 | 2.04 | 1 | 0 |
Vasculitis Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body. | 0 | 2.04 | 1 | 0 |
Alveolar Bone Atrophy [description not available] | 0 | 2.05 | 1 | 0 |
Bright Disease A historical classification which is no longer used. It described acute glomerulonephritis, acute nephritic syndrome, or acute nephritis. Named for Richard Bright. | 0 | 5.2 | 8 | 0 |
Group A Strep Infection [description not available] | 0 | 2.05 | 1 | 0 |
Glomerulonephritis Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY. | 0 | 5.2 | 8 | 0 |
Streptococcal Infections Infections with bacteria of the genus STREPTOCOCCUS. | 0 | 2.05 | 1 | 0 |
Cat Diseases Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used. | 0 | 2.05 | 1 | 0 |
IgA Vasculitis A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections. | 0 | 2.05 | 1 | 0 |
Anterior Cerebral Circulation Infarction [description not available] | 0 | 2.05 | 1 | 0 |
Brain Infarction Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis. | 0 | 2.05 | 1 | 0 |
Anaplastic Astrocytoma [description not available] | 0 | 2.05 | 1 | 0 |
Benign Neoplasms, Brain [description not available] | 0 | 2.05 | 1 | 0 |
Astrocytoma Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) | 0 | 7.05 | 1 | 0 |
Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 2.05 | 1 | 0 |
Bone Inflammation [description not available] | 0 | 2.05 | 1 | 0 |
Prosthesis Durability [description not available] | 0 | 2.05 | 1 | 0 |
Corneal Diseases Diseases of the cornea. | 0 | 2.05 | 1 | 0 |
Anochlesia [description not available] | 0 | 2.05 | 1 | 0 |
Toxoplasmosis, Animal Acquired infection of non-human animals by organisms of the genus TOXOPLASMA. | 0 | 2.43 | 2 | 0 |
Carotid Artery Narrowing [description not available] | 0 | 2.05 | 1 | 0 |
Carotid Stenosis Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3) | 0 | 2.05 | 1 | 0 |
Anterior Choroidal Artery Infarction [description not available] | 0 | 2.05 | 1 | 0 |
Cerebral Infarction The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction). | 0 | 2.05 | 1 | 0 |
Central Retinal Edema, Cystoid [description not available] | 0 | 3.68 | 3 | 0 |
Macular Edema Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90) | 0 | 3.68 | 3 | 0 |
Breast Cancer [description not available] | 0 | 2.06 | 1 | 0 |
Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 2.06 | 1 | 0 |
Inflammatory Response Syndrome, Systemic [description not available] | 0 | 2.06 | 1 | 0 |
Systemic Inflammatory Response Syndrome A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever | 0 | 2.06 | 1 | 0 |
Bacteroidaceae Infections Infections with bacteria of the family BACTEROIDACEAE. | 0 | 2.43 | 2 | 0 |
Temporomandibular Disorders [description not available] | 0 | 2.06 | 1 | 0 |
Temporomandibular Joint Disorders A variety of conditions affecting the anatomic and functional characteristics of the temporomandibular joint. Factors contributing to the complexity of temporomandibular diseases are its relation to dentition and mastication and the symptomatic effects in other areas which account for referred pain to the joint and the difficulties in applying traditional diagnostic procedures to temporomandibular joint pathology where tissue is rarely obtained and x-rays are often inadequate or nonspecific. Common diseases are developmental abnormalities, trauma, subluxation, luxation, arthritis, and neoplasia. (From Thoma's Oral Pathology, 6th ed, pp577-600) | 0 | 2.06 | 1 | 0 |
Acute Promyelocytic Leukemia [description not available] | 0 | 2.69 | 3 | 0 |
Leukemia, Promyelocytic, Acute An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION. | 0 | 2.69 | 3 | 0 |
Libman-Sacks Disease [description not available] | 0 | 2.06 | 1 | 0 |
Nephritis Inflammation of any part of the KIDNEY. | 0 | 2.06 | 1 | 0 |
Lupus Erythematosus, Systemic A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. | 0 | 2.06 | 1 | 0 |
Lesion of Sciatic Nerve [description not available] | 0 | 2.07 | 1 | 0 |
Nerve Root Avulsion [description not available] | 0 | 2.07 | 1 | 0 |
Radiculopathy Disease involving a spinal nerve root (see SPINAL NERVE ROOTS) which may result from compression related to INTERVERTEBRAL DISK DISPLACEMENT; SPINAL CORD INJURIES; SPINAL DISEASES; and other conditions. Clinical manifestations include radicular pain, weakness, and sensory loss referable to structures innervated by the involved nerve root. | 0 | 2.07 | 1 | 0 |
Asthmatic Crisis [description not available] | 0 | 2.48 | 2 | 0 |
Status Asthmaticus A sudden intense and continuous aggravation of a state of asthma, marked by dyspnea to the point of exhaustion and collapse and not responding to the usual therapeutic efforts. | 0 | 2.48 | 2 | 0 |
Bronchiolitis Inflammation of the BRONCHIOLES. | 0 | 2.06 | 1 | 0 |
Gastroenteritis INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER. | 0 | 2.06 | 1 | 0 |
Aspirin Induced Asthma [description not available] | 0 | 2.06 | 1 | 0 |
Age-Related Macular Degeneration [description not available] | 0 | 2.07 | 1 | 0 |
Macular Degeneration Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms. | 0 | 2.07 | 1 | 0 |
Airflow Obstruction, Chronic [description not available] | 0 | 2.74 | 3 | 0 |
Pulmonary Disease, Chronic Obstructive A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA. | 0 | 2.74 | 3 | 0 |
Sclerosis, Systemic [description not available] | 0 | 2.45 | 2 | 0 |
Scleroderma, Systemic A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. | 0 | 2.45 | 2 | 0 |
Drug Withdrawal Symptoms [description not available] | 0 | 2.07 | 1 | 0 |
Substance Withdrawal Syndrome Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug. | 0 | 2.07 | 1 | 0 |
Injuries, Tendon [description not available] | 0 | 2.48 | 2 | 0 |
Colitis Gravis [description not available] | 0 | 2.45 | 2 | 0 |
Colitis, Ulcerative Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN. | 0 | 2.45 | 2 | 0 |
Injuries, Eye [description not available] | 0 | 2.46 | 2 | 0 |
Eye Injuries Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries. | 0 | 2.46 | 2 | 0 |
Atopic Hypersensitivity [description not available] | 0 | 2.07 | 1 | 0 |
Acute Kidney Failure [description not available] | 0 | 2.07 | 1 | 0 |
Rhabdomyolysis Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. | 0 | 7.07 | 1 | 0 |
Acute Kidney Injury Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 7.07 | 1 | 0 |
Albuminuria The presence of albumin in the urine, an indicator of KIDNEY DISEASES. | 0 | 2.07 | 1 | 0 |
Asystole [description not available] | 0 | 2.08 | 1 | 0 |
Heart Arrest Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation. | 0 | 2.08 | 1 | 0 |
Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. | 0 | 3 | 1 | 0 |
Cognition Disorders Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment. | 0 | 3 | 1 | 0 |
Papilloma, Squamous Cell [description not available] | 0 | 2.08 | 1 | 0 |
Papilloma A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed) | 0 | 2.08 | 1 | 0 |
Bronchitis Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI. | 0 | 2.01 | 1 | 0 |
Infection, Toxoplasma gondii [description not available] | 0 | 2.01 | 1 | 0 |
Toxoplasmosis The acquired form of infection by Toxoplasma gondii in animals and man. | 0 | 2.01 | 1 | 0 |
Delayed Hypersensitivity [description not available] | 0 | 2.41 | 2 | 0 |
Gastritis Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders. | 0 | 2.42 | 2 | 0 |
Neutropenia A decrease in the number of NEUTROPHILS found in the blood. | 0 | 2.02 | 1 | 0 |
Mastitis, Bovine INFLAMMATION of the UDDER in cows. | 0 | 2.01 | 1 | 0 |
Convalescence The period of recovery following an illness. | 0 | 2.02 | 1 | 0 |
Pleurisy INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN. | 0 | 2.93 | 4 | 0 |
Contact Dermatitis [description not available] | 0 | 2.02 | 1 | 0 |
Dermatitis, Contact A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms. | 0 | 2.02 | 1 | 0 |
Age-Related Osteoporosis [description not available] | 0 | 2.93 | 1 | 0 |
Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. | 0 | 2.93 | 1 | 0 |
Osteoporosis Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. | 0 | 2.93 | 1 | 0 |
Graft-Versus-Host Disease [description not available] | 0 | 2.02 | 1 | 0 |
Graft vs Host Disease The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION. | 0 | 2.02 | 1 | 0 |
Acute-Phase Reaction An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma. | 0 | 2.02 | 1 | 0 |
Pulmonary Consumption [description not available] | 0 | 2.02 | 1 | 0 |
Tuberculosis, Pulmonary MYCOBACTERIUM infections of the lung. | 0 | 2.02 | 1 | 0 |
Polyarthritis [description not available] | 0 | 2.94 | 1 | 0 |
Arthritis Acute or chronic inflammation of JOINTS. | 0 | 2.94 | 1 | 0 |
Hematochezia The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea. | 0 | 2.94 | 1 | 0 |
Gastrointestinal Hemorrhage Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. | 0 | 2.94 | 1 | 0 |
Parasite Infections [description not available] | 0 | 2.03 | 1 | 0 |
Ache [description not available] | 0 | 2.03 | 1 | 0 |
Pain An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 2.03 | 1 | 0 |
DDD MPGNII [description not available] | 0 | 2.03 | 1 | 0 |
Glomerulonephritis, Membranoproliferative Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN. | 0 | 2.03 | 1 | 0 |
Pocket, Periodontal [description not available] | 0 | 3.42 | 1 | 1 |
Hemorrhage, Gingival [description not available] | 0 | 3.42 | 1 | 1 |
Gingival Hemorrhage The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY. | 0 | 3.42 | 1 | 1 |
Gingivitis Inflammation of gum tissue (GINGIVA) without loss of connective tissue. | 0 | 3.42 | 1 | 1 |
Periodontal Pocket An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption. | 0 | 3.42 | 1 | 1 |
Allergy, Drug [description not available] | 0 | 2.03 | 1 | 0 |
Drug Hypersensitivity Immunologically mediated adverse reactions to medicinal substances used legally or illegally. | 0 | 2.03 | 1 | 0 |
Plica Syndrome [description not available] | 0 | 2.03 | 1 | 0 |
Synovitis Inflammation of the SYNOVIAL MEMBRANE. | 0 | 7.03 | 1 | 0 |
Hypersensitivity, Type III [description not available] | 0 | 1.98 | 1 | 0 |
Proteinuria The presence of proteins in the urine, an indicator of KIDNEY DISEASES. | 0 | 1.99 | 1 | 0 |
Leukemia, Acute Monocytic [description not available] | 0 | 1.99 | 1 | 0 |
Leukemia, Monocytic, Acute An acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage including monoblasts, promonocytes, and MONOCYTES. | 0 | 1.99 | 1 | 0 |
Ascites Accumulation or retention of free fluid within the peritoneal cavity. | 0 | 1.99 | 1 | 0 |
Dermatitis Any inflammation of the skin. | 0 | 2.91 | 1 | 0 |
Eosinophilia, Tropical [description not available] | 0 | 2.68 | 3 | 0 |
Angiostrongylus Infections [description not available] | 0 | 2 | 1 | 0 |
Eosinophilia Abnormal increase of EOSINOPHILS in the blood, tissues or organs. | 0 | 7.68 | 3 | 0 |
Pleural Effusion Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. | 0 | 3.32 | 2 | 0 |
Kahler Disease [description not available] | 0 | 2 | 1 | 0 |
Multiple Myeloma A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. | 0 | 2 | 1 | 0 |
Aggressive Periodontitis Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people. | 0 | 2 | 1 | 0 |
Basophilic Leukemia, Acute [description not available] | 0 | 2.67 | 3 | 0 |
Leukemia, Basophilic, Acute A rare acute myeloid leukemia in which the primary differentiation is to BASOPHILS. It is characterized by an extreme increase of immature basophilic granulated cells in the bone marrow and blood. Mature basophils are usually sparse. | 0 | 2.67 | 3 | 0 |
Glomerulonephritis, Lupus [description not available] | 0 | 2.92 | 1 | 0 |
Lupus Nephritis Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982). | 0 | 2.92 | 1 | 0 |
Di Guglielmo Disease [description not available] | 0 | 2.37 | 2 | 0 |
Leukemia, Erythroblastic, Acute A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood. | 0 | 2.37 | 2 | 0 |
Blast Phase [description not available] | 0 | 1.97 | 1 | 0 |
Granulocytic Leukemia, Chronic [description not available] | 0 | 2.67 | 3 | 0 |
Blast Crisis An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%. | 0 | 1.97 | 1 | 0 |
Myeloproliferative Disorders Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE. | 0 | 2.38 | 2 | 0 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS. | 0 | 2.67 | 3 | 0 |
Besnier-Boeck Disease [description not available] | 0 | 1.97 | 1 | 0 |
Sarcoidosis An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands. | 0 | 1.97 | 1 | 0 |
Granulomas [description not available] | 0 | 1.97 | 1 | 0 |
Granuloma A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents. | 0 | 1.97 | 1 | 0 |