Geranylgeranyl pyrophosphate synthase

A geranylgeranyl pyrophosphate synthase that is encoded in the genome of yeast. [OMA:Q12051, PRO:DNx]

Synonyms

GGPP synthase;
GGPPSase;
EC 2.5.1.-;
(2E,6E)-farnesyl diphosphate synthase;
BET2 suppressor protein 1;
Dimethylallyltranstransferase;
2.5.1.1;
Farnesyl diphosphate synthase;
Farnesyltranstransferase;
2.5.1.29;
Gera

Research

Bioassay Publications (2)

Timeframe	Studies on this Protein(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Compounds (3)

Drugs with Inhibition Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
zoledronic acid	Saccharomyces cerevisiae S288C	IC50	14.6491	3	7
zoledronic acid	Saccharomyces cerevisiae S288C	Ki	0.2600	1	1
ym 529	Saccharomyces cerevisiae S288C	IC50	0.3400	1	1
ym 529	Saccharomyces cerevisiae S288C	Ki	0.1300	1	1

Drugs with Other Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
farnesyl pyrophosphate	Saccharomyces cerevisiae S288C	Km	3.2000	1	1