proglumide has been researched along with Sensitivity and Specificity in 4 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Increased gastric emptying and defective action of endogenous cholecystokinin (CCK), that is known to inhibit this emptying, have been implicated in the pathogenesis of duodenal ulcer (DU)." | 9.09 | Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on gastric motility in duodenal ulcer patients. ( Domschke, W; Konturek, JW; Konturek, M; Konturek, SJ; Menzel, J; Stoll, R, 2001) |
| "Increased gastric emptying and defective action of endogenous cholecystokinin (CCK), that is known to inhibit this emptying, have been implicated in the pathogenesis of duodenal ulcer (DU)." | 5.09 | Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on gastric motility in duodenal ulcer patients. ( Domschke, W; Konturek, JW; Konturek, M; Konturek, SJ; Menzel, J; Stoll, R, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Rizzo, M | 1 |
| Ventrice, D | 1 |
| Monforte, F | 1 |
| Procopio, S | 1 |
| De Sarro, G | 1 |
| Anzini, M | 1 |
| Cappelli, A | 1 |
| Makovec, F | 1 |
| Fanali, S | 1 |
| D'Orazio, G | 1 |
| Quaglia, MG | 1 |
| Rocco, A | 1 |
| Konturek, JW | 1 |
| Stoll, R | 1 |
| Menzel, J | 1 |
| Konturek, M | 1 |
| Konturek, SJ | 1 |
| Domschke, W | 1 |
1 trial available for proglumide and Sensitivity and Specificity
| Article | Year |
|---|---|
Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on gastric motility in duodenal ulcer patients.
Topics: Adolescent; Adult; Analysis of Variance; Cholecystokinin; Duodenal Ulcer; Follow-Up Studies; Gastric | 2001 |
3 other studies available for proglumide and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Sensitive SPE-HPLC method to determine a novel angiotensin-AT1 antagonist in biological samples.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Chromatography, High Pressure Liquid; Proglumide; | 2004 |
Use of a hepta-Tyr antibiotic modified silica stationary phase for the enantiomeric resolution of D,L-loxiglumide by electrochromatography and nano-liquid chromatography.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Na | 2004 |