Compounds > trichloroethyl chloroformate
Page last updated: 2024-11-06

trichloroethyl chloroformate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

trichloroethyl chloroformate: reagent for gas chromatographic analysis of pethidine; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID87063
SCHEMBL ID3023
MeSH IDM0059707

Synonyms (57)

Synonym
carbonochloridic acid, 2,2,2-trichloroethyl ester
formic acid, chloro-, 2,2,2-trichloroethyl ester
2,2-trichloroethoxycarbonyl chloride
trichloroethyl chloroformate
nsc-152038
nsc152038
carbonochloridic acid,2,2-trichloroethyl ester
17341-93-4
2,2-trichloroethyl chloroformate
formic acid, 2,2,2-trichloroethyl ester
2,2,2-trichloroethyl chloroformate, 98%
chloroformic acid 2,2,2-trichloroethyl ester
ljcznywlqzzios-uhfffaoysa-
inchi=1/c3h2cl4o2/c4-2(8)9-1-3(5,6)7/h1h2
2,2,2-trichloroethyl chloroformate
2,2,2-trichloroethylchloroformate
2,2,2-trichloroethyl carbonochloridate
99uy6lzn4r ,
unii-99uy6lzn4r
nsc 152038
einecs 241-363-7
2,2,2-trichloroethoxycarbonyl chloride
AKOS015917631
chloro(2,2,2-trichloroethoxy)methanone
FT-0637537
SCHEMBL3023
DTXSID3066188
trichloroethoxycarbonyl chloride
2,2,2-trichloroethyoxycarbonyl chloride
troc-cl
2,2,2-trichioroethoxycarbonyl chloride
2,2,2trichloroethyl chloroformate
troc
2,2,2-tri-chloroethyl chloroformate
clco2ch2ccl3
2,2,2-trichloroethyl-chloroformate
troccl
2,2,2-trichloroethyl chloro-formate
2,2,2-trichloroethyl chlorocarbonate
2,2,2-trichloroethoxycarbonylchloride
beta,beta,beta-trichloroethyl chloroformate
2,2,2-trichloroethylchlorocarbonate
chloroformic acid-2,2,2-trichloroethyl ester
2,2,2-trichloroethyl chlorioformate
trichloroethylchloroformate
2,2,2-trichloroethyloxycarbonyl chloride
W-107862
STR02674
2,2,2-trichloroethyl chloridocarbonate #
mfcd00000810
2,2,2-trichloroethyl chloroformate, purum, >=98.0% (nt)
troc-cl trichloroethoxycarbonyl chloride
C93433
carbonochloridic acid 2,2,2-trichloroethyl ester
.beta.,.beta.,.beta.-trichloroethoxycarbonyl chloride
.beta.,.beta.,.beta.-trichloroethyl chloroformate
EN300-268363
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (27.27)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.26

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.26 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.87 (4.65)
Search Engine Demand Index29.80 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (30.26)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
quinacrine
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.. quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.		1.9610acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
chloroquine
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.		1.9610aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
amphetamine
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.. 1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.. amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.		6.9910primary amine
meperidine
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.. pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.		2.3620ethyl ester;
piperidinecarboxylate ester;
tertiary amino compound		antispasmodic drug;
kappa-opioid receptor agonist;
mu-opioid receptor agonist;
opioid analgesic
mexiletine
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.. mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.		6.9910aromatic ether;
primary amino compound		anti-arrhythmia drug
phenmetrazine
Phenmetrazine: A sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to DEXTROAMPHETAMINE.. phenmetrazine : A member of the class of morpholines that is morpholine substituted with a phenyl group at position 2 and a methyl group at position 3.		6.9910morpholinesmetabolite;
sympathomimetic agent
dextroamphetamine
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.. (S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.		1.99101-phenylpropan-2-amineadrenergic agent;
adrenergic uptake inhibitor;
dopamine uptake inhibitor;
dopaminergic agent;
neurotoxin;
sympathomimetic agent
aniline
[no description available]		6.9910anilines;
primary arylamine
chloroform
Chloroform: A commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.. chloroform : A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.		6.9610chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
phosgene
Phosgene: A highly toxic gas that has been used as a chemical warfare agent. It is an insidious poison as it is not irritating immediately, even when fatal concentrations are inhaled. (From The Merck Index, 11th ed, p7304). phosgene : An acyl chloride obtained by substitution of both hydrogens of formaldehyde by chlorine.. chloroketone : A ketone containing a chloro substituent.		3.78110acyl chloride
ephedrine
Ephedrine: A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.. (-)-ephedrine : A phenethylamine alkaloid that is 2-phenylethanamine substituted by a methyl group at the amino nitrogen and a methyl and a hydroxy group at position 2 and 1 respectively.		7.0210phenethylamine alkaloid;
phenylethanolamines		bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
methamphetamine
Methamphetamine: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.. methamphetamine : A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.		7.4220amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
bromine
Bromine: A halogen with the atomic symbol Br, atomic number 35, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested.		2.1110diatomic bromine
normeperidine
normeperidine: RN given refers to parent cpd; structure		1.9610
4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline
4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline: formed by reaction of chloroquine with trichloroethyl chloroformate		1.9610
d-n-propylamphetamine
d-N-propylamphetamine: RN given refers to cpd without isomeric designation		1.9910
bilirubin
[no description available]		1.9910biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
mephedrone
mephedrone: a beta-keto (bk) designer drug; Central Nervous System Stimulants. mephedrone : An aromatic ketone that is propiophenone substituted at C-4 and at C-beta with methyl and methylamino groups respectively. It is a synthetic stimulant and entactogen drug of the amphetamine and cathinone classes.		7.0610amphetamines;
aromatic ketone;
secondary amino compound		environmental contaminant;
xenobiotic
ConditionIndicatedRelationship StrengthStudiesTrials
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.9140
Extravascular Hemolysis
[description not available]		01.9910
Hemolysis
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.		01.9910