Page last updated: 2024-08-07 19:33:52
Endochitinase B1
[no definition available]
Synonyms
EC 3.2.1.14;
Chitinase B1
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (5)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| theophylline | Aspergillus fumigatus | IC50 | 1,000.0000 | 1 | 2 |
| caffeine | Aspergillus fumigatus | IC50 | 363.0000 | 1 | 2 |
| pentoxifylline | Aspergillus fumigatus | IC50 | 98.0000 | 1 | 1 |
| pentoxifylline | Aspergillus fumigatus | Ki | 37.0000 | 1 | 1 |
| argadin | Aspergillus fumigatus | IC50 | 0.2565 | 1 | 2 |
| argadin | Aspergillus fumigatus | Ki | 0.0200 | 1 | 1 |
| argifin | Aspergillus fumigatus | IC50 | 2.5317 | 2 | 4 |
| argifin | Aspergillus fumigatus | Ki | 16.5085 | 2 | 2 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| pentoxifylline | Aspergillus fumigatus | Kd | 52.7000 | 1 | 10 |
| argadin | Aspergillus fumigatus | Kd | 3.6500 | 1 | 8 |
| argifin | Aspergillus fumigatus | Kd | 2.1400 | 1 | 7 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| argifin | Aspergillus fumigatus | Km | 10.4000 | 1 | 1 |
Structure-based dissection of the natural product cyclopentapeptide chitinase inhibitor argifin.Chemistry & biology, , Volume: 15, Issue:3, 2008
Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases.Chemistry & biology, , Volume: 12, Issue:1, 2005
An efficient synthesis of argifin: a natural product chitinase inhibitor with chemotherapeutic potential.Bioorganic & medicinal chemistry letters, , Nov-01, Volume: 15, Issue:21, 2005