Page last updated: 2024-08-07 16:12:22
Aromatase
An aromatase that is encoded in the genome of rat. [OMA:P22443, PRO:DNx]
Synonyms
EC 1.14.14.14;
CYPXIX;
Cytochrome P-450AROM;
Cytochrome P450 19A1;
Estrogen synthase
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
Compounds (11)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| aminoglutethimide | Rattus norvegicus (Norway rat) | IC50 | 20.1000 | 2 | 2 |
| citalopram | Rattus norvegicus (Norway rat) | IC50 | 0.0018 | 1 | 1 |
| talopram | Rattus norvegicus (Norway rat) | IC50 | 1.4000 | 1 | 1 |
| talsupram | Rattus norvegicus (Norway rat) | IC50 | 0.8500 | 1 | 1 |
| (S)-nomifensine | Rattus norvegicus (Norway rat) | IC50 | 0.8300 | 1 | 1 |
| 7-((4'-aminophenyl)thio)-1,4-androstadiene-3,17-dione | Rattus norvegicus (Norway rat) | Ki | 0.0180 | 1 | 1 |
| ly 56110 | Rattus norvegicus (Norway rat) | Ki | 0.0290 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| aminoglutethimide | Rattus norvegicus (Norway rat) | EC50 | 0.2600 | 1 | 1 |
| miconazole | Rattus norvegicus (Norway rat) | EC50 | 0.4000 | 1 | 1 |
| ancymidol | Rattus norvegicus (Norway rat) | EC50 | 2.0000 | 1 | 1 |
| fenarimol | Rattus norvegicus (Norway rat) | EC50 | 4.1000 | 1 | 1 |
| ly 56110 | Rattus norvegicus (Norway rat) | EC50 | 0.0550 | 2 | 2 |
| octotiamine | Rattus norvegicus (Norway rat) | EC50 | 0.1400 | 1 | 1 |