Compounds > 6-nitrochrysene
Page last updated: 2024-09-22

6-nitrochrysene

Description

6-nitrochrysene: RN given refers to cpd with locant for nitro group in position 6 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID24121
CHEMBL ID82858
CHEBI ID82351
SCHEMBL ID710252
MeSH IDM0109904

Synonyms (30)

Synonym
chebi:82351 ,
6-nitro-chrysene
CHEMBL82858 ,
6-nitrochrysene [nitroarenes]
nsc 407609
chrysene, 6-nitro-
6-nitrochrysene
brn 2134652
ccris 2975
nsc407609
7496-02-8
nsc-407609
bdbm50128865
C19271
unii-82zk83o33y
82zk83o33y ,
hsdb 7770
3-05-00-02383 (beilstein handbook reference)
6-nitrochrysene [hsdb]
nitrochrysene, 6-
6-nitrochrysene [iarc]
SCHEMBL710252
AKOS024386611
4-nitrochrysene #
UAWLTQJFZUYROA-UHFFFAOYSA-N
DTXSID9075454
6-nitrochrysene, bcr(r) certified reference material
Q27155892
FT-0778180
6-nitrochrysene (purity)

Drug Classes (1)

ClassDescription
carbopolycyclic compoundA polyclic compound in which all of the ring members are carbon atoms.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Hypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)Ki6.70000.60005.54678.9800AID93178
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (24)

Processvia Protein(s)Taxonomy
T cell mediated cytotoxicityHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
response to amphetamineHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
purine nucleotide biosynthetic processHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
purine ribonucleoside salvageHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
guanine salvageHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
grooming behaviorHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
locomotory behaviorHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
striatum developmentHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
cerebral cortex neuron differentiationHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
central nervous system neuron developmentHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
GMP salvageHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
IMP salvageHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
dopamine metabolic processHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
hypoxanthine salvageHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
AMP salvageHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
positive regulation of dopamine metabolic processHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
GMP catabolic processHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
IMP metabolic processHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
adenine metabolic processHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
hypoxanthine metabolic processHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
lymphocyte proliferationHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
dendrite morphogenesisHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
protein homotetramerizationHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
dopaminergic neuron differentiationHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (6)

Processvia Protein(s)Taxonomy
nucleotide bindingHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
magnesium ion bindingHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
hypoxanthine phosphoribosyltransferase activityHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
protein bindingHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
identical protein bindingHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
guanine phosphoribosyltransferase activityHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (3)

Processvia Protein(s)Taxonomy
cytoplasmHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
cytosolHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
extracellular exosomeHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
cytosolHypoxanthine-guanine phosphoribosyltransferaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID200690Mutagenic activity in an Ames test on Salmonella Typhimurium TA98; Activity is log of revertants/nmol1991Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
AID93178Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)2003Journal of medicinal chemistry, Jun-05, Volume: 46, Issue:12
Analysis of 6-(2,2-Dichloroacetamido)chrysene interaction with the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi.
AID23442Partition coefficient (logP)1991Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (68)

TimeframeStudies, This Drug (%)All Drugs %
pre-199018 (26.47)18.7374
1990's24 (35.29)18.2507
2000's14 (20.59)29.6817
2010's9 (13.24)24.3611
2020's3 (4.41)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (2.90%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other67 (97.10%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
dinitrochlorobenzene[no description available]medium10C-nitro compound;
monochlorobenzenes		allergen;
epitope;
sensitiser
4-nitrobenzaldehyde[no description available]medium10benzaldehydes;
C-nitro compound
7-nitroindazole[no description available]medium10
metronidazole[no description available]medium10C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
niridazole[no description available]medium101,3-thiazoles;
C-nitro compound
dinitrofluorobenzene[no description available]medium10C-nitro compound;
organofluorine compound		agrochemical;
allergen;
chromatographic reagent;
EC 2.7.3.2 (creatine kinase) inhibitor;
protein-sequencing agent;
spectrophotometric reagent
1-nitronaphthalene[no description available]medium30mononitronaphthaleneenvironmental contaminant;
mouse metabolite
1-chloro-2-nitrobenzene[no description available]medium10C-nitro compound;
monochlorobenzenes
2,5-dichloronitrobenzene[no description available]medium10
2-nitroanisole[no description available]medium102-nitroanisolescarcinogenic agent
4-nitrobiphenyl[no description available]medium10biphenyls
2,4-dinitroaniline[no description available]medium10nitroaniline
nitrobenzene[no description available]medium10nitroarene;
nitrobenzenes
1,2-dichloro-4-nitrobenzene[no description available]medium10
3-dinitrobenzene[no description available]medium10dinitrobenzeneneurotoxin
4-chloronitrobenzene[no description available]medium10C-nitro compound
4-nitroanisole[no description available]medium104-nitroanisoles
4-nitroacetophenone[no description available]medium10acetophenones;
C-nitro compound
1,4-dinitrobenzene[no description available]medium10dinitrobenzene
2,4-dinitroanisole[no description available]medium10dinitroanisolesexplosive
2,4,7-trinitrofluorenone[no description available]medium10
1,2-dinitrobenzene[no description available]medium10dinitrobenzene
2-nitrobenzaldehyde[no description available]medium10benzaldehydes;
C-nitro compound
2-nitronaphthalene[no description available]medium10mononitronaphthalene
9-nitroanthracene[no description available]medium20anthracenes
5-nitroacenaphthene[no description available]medium10nitronaphthalene
erythropoietin[no description available]medium10dinitronaphthalenegenotoxin
1,3-dinitronaphthalene[no description available]medium10dinitronaphthalene
5-nitroquinoline[no description available]medium10
2-nitrofluorene[no description available]medium30nitroarenecarcinogenic agent;
mutagen
2,4-dichloro-1-nitrobenzene[no description available]medium10
5-nitro-2-furaldehyde[no description available]medium10C-nitro compound;
furans
2-nitropyrene[no description available]medium20pyrenes
3-nitrofluoranthene[no description available]medium60nitronaphthalene
2-amino-7-nitrofluorene[no description available]medium10
2-bromo-4,6-dinitroaniline[no description available]medium10
5-nitroindazole[no description available]medium10
2,7-dinitrofluorene[no description available]medium10
1-nitropyrene[no description available]medium150nitroarenecarcinogenic agent
nsc 520594[no description available]medium10
2-hydroxy-7-nitrofluorene[no description available]medium10
6-nitroindazole[no description available]medium10
2-nitrofluoranthene[no description available]medium20
7-nitrobenzanthracene[no description available]medium30phenanthrenes
3,9-dinitrofluoranthene[no description available]medium10nitronaphthalene
2,7-dinitrofluorenone[no description available]medium10
1,6-dinitropyrene[no description available]medium30pyrenes
1,8-dinitropyrene[no description available]medium10pyrenes
6-nitrobenzo(a)pyrene[no description available]medium60ortho- and peri-fused polycyclic arene
1-nitrobenzo(a)pyrene[no description available]medium30
3-nitrobenzo(a)pyrene[no description available]medium30
1,3-dinitropyrene[no description available]medium20pyrenes
3,7-dinitrofluoranthene[no description available]medium10nitronaphthalene
4-nitropyrene[no description available]medium40pyrenes
3-nitroperylene[no description available]medium20phenanthrenes
1-nitro-2,4-difluorobenzene[no description available]medium10
5-nitroisoquinoline[no description available]medium10
9-nitrophenanthrene[no description available]medium20
5-nitro-1,10-phenanthroline[no description available]medium10
1-fluoro-2-nitrobenzene[no description available]medium10
2-nitrobenzimidazole[no description available]medium10
2,4-dinitrophenylhydrazine[no description available]medium10C-nitro compound;
phenylhydrazines		reagent
2-nitro-4-phenylenediamine[no description available]medium10C-nitro compound;
primary amino compound
5-Nitroisatin[no description available]medium10indolesanticoronaviral agent
2-amino-5-nitrophenol[no description available]medium103-nitrophenols
1,2-diamino-4-nitrobenzene[no description available]medium10C-nitro compound;
primary amino compound
furazolidone[no description available]medium10
nitrofurazone[no description available]medium10
nitrofurantoin[no description available]medium10imidazolidine-2,4-dione;
nitrofuran antibiotic;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic		antibacterial drug;
antiinfective agent;
hepatotoxic agent
chrysene[no description available]medium30ortho-fused polycyclic areneplant metabolite
6-chrysenamine[no description available]medium60carbopolycyclic compound
benzo(a)pyrene[no description available]medium100ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
2,4-dinitrophenol[no description available]medium10dinitrophenolallergen;
antiseptic drug;
bacterial xenobiotic metabolite;
geroprotector;
oxidative phosphorylation inhibitor
methanol[no description available]medium10alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
4-nitrophenol[no description available]medium104-nitrophenolshuman xenobiotic metabolite;
mouse metabolite
nitrates[no description available]medium10monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
nitrophenols[no description available]medium10
cocaine[no description available]medium10benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
2'-deoxyadenosine[no description available]medium10purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
9,10-anthraquinone[no description available]medium10anthraquinone
adenine[no description available]medium106-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
guanine[no description available]medium102-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
oligonucleotides[no description available]medium20
hopane[no description available]medium20terpenoid fundamental parent;
triterpene
phenanthrenes[no description available]medium190
chlorodiphenyl (54% chlorine)[no description available]medium10
deoxyguanosine[no description available]medium40purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine[no description available]medium20imidazopyridine;
primary amino compound		carcinogenic agent;
mutagen
8-hydroxy-2'-deoxyguanosine[no description available]medium10guanosinesbiomarker
perylene[no description available]medium10ortho- and peri-fused polycyclic arene;
perylenes
ethylnitrosourea[no description available]medium10N-nitrosoureasalkylating agent;
carcinogenic agent;
genotoxin;
mutagen
ethyl methanesulfonate[no description available]medium10methanesulfonate esteralkylating agent;
antineoplastic agent;
carcinogenic agent;
genotoxin;
mutagen;
teratogenic agent
pyrene[no description available]medium10ortho- and peri-fused polycyclic arenefluorescent probe;
persistent organic pollutant
benz(a)anthracene[no description available]medium10ortho-fused polycyclic arene;
tetraphenes
transforming growth factor beta[no description available]medium10
phosphorus radioisotopes[no description available]medium10
dimethyl sulfoxide[no description available]medium10sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
4-biphenylamine[no description available]medium10aminobiphenylcarcinogenic agent
aflatoxin b1[no description available]medium20aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
benzo(a)pyrene 7,8-dihydrodiol[no description available]medium10pyrenes
dimethylnitrosamine[no description available]medium10nitrosaminegeroprotector;
mutagen
3-amino-1-methyl-5h-pyrido(4,3-b)indole[no description available]medium10pyridoindole
3-amino-1,4-dimethyl-5h-pyrido(4,3-b)indole[no description available]medium10pyridoindole
3-methylcholanthrene[no description available]medium20ortho- and peri-fused polycyclic arenearyl hydrocarbon receptor agonist;
carcinogenic agent
2'-deoxy-5'-adenosine monophosphate[no description available]medium102'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-monophosphate		fundamental metabolite
2'-deoxyguanosine 5'-phosphate[no description available]medium10deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
mouse metabolite
methylnitronitrosoguanidine[no description available]medium10nitroso compoundalkylating agent
phenobarbital[no description available]medium10barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
cyclopenta(c,d)pyrene[no description available]medium10pyrenes
deoxyinosine[no description available]medium10purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
inosine[no description available]medium10inosines;
purines D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
tetradecanoylphorbol acetate[no description available]medium10acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
benzotriphenylene[no description available]low00carbopolycyclic compound
6-methylchrysene[no description available]low00carbopolycyclic compound
5-methylchrysene[no description available]low00carbopolycyclic compound
benzo(a)pyrene 4,5-epoxide[no description available]low00carbopolycyclic compound
rhodomycinone[no description available]low00carbopolycyclic compound;
methyl ester;
polyphenol;
tetracenequinones;
tetracenomycin
2,2'-spirobi[3,6,7,8-tetrahydro-1H-cyclopenta[g]naphthalene]-5,5'-dione[no description available]low00carbopolycyclic compound;
cyclic ketone;
diketone;
spiro compound		antiviral agent
pallidol[no description available]low00carbopolycyclic compound;
polyphenol;
stilbenoid		antifungal agent;
antioxidant;
plant metabolite
ly335979[no description available]low00carbopolycyclic compound
demethylzeylasteral[no description available]low00arenecarbaldehyde;
benzenediols;
carbopolycyclic compound;
cyclic ketone;
enone;
oxo monocarboxylic acid		anti-inflammatory agent;
EC 2.4.1.17 (glucuronosyltransferase) inhibitor;
immunosuppressive agent;
nephroprotective agent;
plant metabolite
berkeleytrione[no description available]low00beta-diketone;
carbopolycyclic compound;
cyclic terpene ketone;
meroterpenoid;
methyl ester;
tertiary alcohol;
tertiary alpha-hydroxy ketone		cysteine protease inhibitor;
Penicillium metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Adenocarcinoma0low30
Adenocarcinoma, Basal Cell0low30
Adenocarcinoma, Granular Cell0low30
Adenocarcinoma, Oxyphilic0low30
Adenocarcinoma, Tubular0low30
Adenoma0low80
Adenoma, Basal Cell0low80
Adenoma, Follicular0low80
Adenoma, Hepatocellular0low10
Adenoma, Liver Cell0low10
Adenoma, Malignant0low30
Adenoma, Microcystic0low80
Adenoma, Monomorphic0low80
Adenoma, Papillary0low80
Adenoma, Trabecular0low80
Breast Cancer0low10
Breast Carcinoma0low10
Breast Neoplasms0low10
Breast Tumors0low10
Cancer of Breast0low10
Cancer of Colon0low20
Cancer of Liver0low20
Cancer of Lung0low90
Cancer of Skin0low20
Cancer of Stomach0low10
Cancer of the Breast0low10
Cancer of the Colon0low20
Cancer of the Liver0low20
Cancer of the Lung0low90
Cancer of the Skin0low20
Cancer of the Stomach0low10
Cancer, Hepatocellular0low20
Carcinoma, Cribriform0low30
Carcinoma, Epidermoid0low10
Carcinoma, Granular Cell0low30
Carcinoma, Hepatocellular0low20
Carcinoma, Planocellular0low10
Carcinoma, Squamous0low10
Carcinoma, Squamous Cell0low10
Carcinoma, Tubular0low30
Cell Transformation, Neoplastic0low40
Colon Cancer0low20
Colon Neoplasms0low20
Colonic Cancer0low20
Colonic Neoplasms0low20
Condition, Preneoplastic0low10
Conditions, Preneoplastic0low10
Diathesis0low10
Disease Susceptibility0low10
Experimental Hepatoma0low50
Experimental Hepatomas0low50
Experimental Liver Neoplasms0low50
Experimental Mammary Neoplasms0low40
Experimental Neoplasms0low30
Fibroadenoma0low10
Gastric Cancer0low10
Gastric Cancer, Familial Diffuse0low10
Gastric Neoplasms0low10
Hepatic Cancer0low20
Hepatic Neoplasms0low20
Hepatocellular Cancer0low20
Hepatocellular Carcinoma0low20
Hepatoma0low20
Hepatoma, Benign0low10
Hepatoma, Experimental0low50
Hepatoma, Morris0low50
Hepatoma, Novikoff0low50
Hepatomas, Experimental0low50
Human Mammary Carcinoma0low10
Liver Cancer0low20
Liver Cancer, Adult0low20
Liver Cell Carcinoma0low20
Liver Cell Carcinoma, Adult0low20
Liver Neoplasms0low20
Liver Neoplasms, Experimental0low50
Lung Cancer0low90
Lung Neoplasms0low90
Malignant Neoplasm of Breast0low10
Malignant Tumor of Breast0low10
Mammary Cancer0low10
Mammary Carcinoma, Human0low10
Mammary Neoplasm, Human0low10
Mammary Neoplasms, Experimental0low40
Mammary Neoplasms, Human0low10
Neoplasms, Breast0low10
Neoplasms, Colonic0low20
Neoplasms, Experimental0low30
Neoplasms, Experimental Liver0low50
Neoplasms, Experimental Mammary0low40
Neoplasms, Gastric0low10
Neoplasms, Hepatic0low20
Neoplasms, Liver0low20
Neoplasms, Lung0low90
Neoplasms, Pulmonary0low90
Neoplasms, Skin0low20
Neoplasms, Stomach0low10
Neoplastic Cell Transformation0low40
Neoplastic Transformation, Cell0low40
Papilloma0low10
Papilloma, Squamous Cell0low10
Papillomatosis0low10
Precancerous Conditions0low10
Pregnancy0low20
Preneoplastic Condition0low10
Preneoplastic Conditions0low10
Pulmonary Cancer0low90
Pulmonary Neoplasms0low90
Sensitivity and Specificity0low10
Skin Cancer0low20
Skin Neoplasms0low20
Squamous Cell Carcinoma0low10
Stomach Cancer0low10
Stomach Neoplasms0low10
Susceptibility, Disease0low10
Tracheal Neoplasms0low10
Transformation, Neoplastic Cell0low40
Tumorigenic Transformation0low40
Tumors, Breast0low10

Research Highlights

Safety/Toxicity (1)

ArticleYear
Cytotoxicity and keratinocyte microsome-mediated mutagenic activation of carcinogens in cultured epidermal cells.
Toxicology letters, May-19, Volume: 115, Issue: 2		2000
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (2)

ArticleYear
Carcinogen-DNA adduct formation in the lungs and livers of preweanling CD-1 male mice following administration of [3H]-6-nitrochrysene, [3H]-6-aminochrysene, and [3H]-1,6-dinitropyrene.
Cancer research, Dec-01, Volume: 47, Issue: 23		1987
Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay.
Carcinogenesis, Volume: 9, Issue: 5		1988
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]