Page last updated: 2024-08-07 18:25:18

Protein skinhead-1

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (82)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
3-hydroxybutyric acidCaenorhabditis elegansIC50100.000010
beta-naphthoflavoneCaenorhabditis elegansIC50100.000010
nsc-526417Caenorhabditis elegansIC5075.850020
disperse red 9Caenorhabditis elegansIC50100.000010
dehydrothio-4-toluidineCaenorhabditis elegansIC50100.000010
3-dimethylaminophenolCaenorhabditis elegansIC50100.000010
5-amino-2-naphthalenesulfonateCaenorhabditis elegansIC50100.000010
thioxanthoneCaenorhabditis elegansIC5065.050020
pifexoleCaenorhabditis elegansIC5042.723330
10,10-dimethylanthroneCaenorhabditis elegansIC5062.000020
quinoxaline-2-carboxylic acidCaenorhabditis elegansIC50100.000010
2-pyridin-4-yl-1,3-benzothiazoleCaenorhabditis elegansIC5057.500020
brusatolCaenorhabditis elegansIC5042.790020
hematoxylinCaenorhabditis elegansIC50100.000010
2-methyl-3-(phenylmethylthio)-1H-indoleCaenorhabditis elegansIC5046.465020
5f-203Caenorhabditis elegansIC5018.700020
2-[(4-nitrophenyl)methylthio]-1,3-benzoxazoleCaenorhabditis elegansIC50100.000010
dibenzylidene acetoneCaenorhabditis elegansIC5013.900020
N-tert-butyl-N-[2-(tert-butylamino)-2-oxoethyl]-3-(3,4-dihydro-2H-quinolin-1-yl)propanamideCaenorhabditis elegansIC50100.000010
5,7-dimethyl-2-(1-pyrrolidinyl)-3-quinolinecarbonitrileCaenorhabditis elegansIC50100.000010
1-[4-[4-[(phenylmethyl)amino]phenyl]-1-piperazinyl]ethanoneCaenorhabditis elegansIC50100.000010
N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamideCaenorhabditis elegansIC50100.000010
2-methoxy-6-[[(1-propyl-5-benzimidazolyl)amino]methyl]phenolCaenorhabditis elegansIC50100.000010
2-(3,4-dichlorophenyl)imidazo[1,2-a]pyrimidineCaenorhabditis elegansIC50100.000010
4-(benzylsulfanyl)thieno[2,3-d]pyrimidineCaenorhabditis elegansIC5086.885020
2-[[2-furanyl(oxo)methyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl esterCaenorhabditis elegansIC50100.000010
N-(2,5-dimethylphenyl)-2-benzofurancarboxamideCaenorhabditis elegansIC50100.000010
2-[(4-bromophenyl)methylthio]-5-(3-pyridinyl)-1,3,4-oxadiazoleCaenorhabditis elegansIC5034.233330
5-bromo-N-(2,4-dichlorophenyl)-2-furancarboxamideCaenorhabditis elegansIC50100.000010
6-(4-chlorophenyl)-2-methyl-3-pyridinecarboxylic acid methyl esterCaenorhabditis elegansIC5082.500010
5-(4-fluorophenyl)-2-thiophen-2-yloxazoleCaenorhabditis elegansIC5025.750020
2-(2-fluorophenyl)-5-(4-methyl-1-piperidinyl)-4-oxazolecarbonitrileCaenorhabditis elegansIC50100.000010
1-benzimidazolyl-[2-(4-methoxyphenyl)-4-quinolinyl]methanoneCaenorhabditis elegansIC50100.000010
N-(1,3-benzothiazol-2-yl)-2-(3-methoxyphenyl)-4-quinolinecarboxamideCaenorhabditis elegansIC50100.000010
N-(9,9-dimethyl-7-oxo-8,10-dihydronaphtho[1,2-b]benzofuran-5-yl)-4-methoxybenzenesulfonamideCaenorhabditis elegansIC50100.000010
5-bromo-N-[2-(3-pyridinyl)-1,3-benzoxazol-5-yl]-2-furancarboxamideCaenorhabditis elegansIC50100.000010
N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-[4-[5-(trifluoromethyl)-1-benzotriazolyl]-1-piperidinyl]acetamideCaenorhabditis elegansIC50100.000010
3-phenyl-5-[(phenylthio)methyl]isoxazoleCaenorhabditis elegansIC5012.596730
3-(4-chlorophenyl)-5-[(phenylthio)methyl]isoxazoleCaenorhabditis elegansIC5059.985020
4-(3-chloro-2-thiophenyl)-2-(3-pyridinyl)thiazoleCaenorhabditis elegansIC50100.000010
N-(3,4-dichlorophenyl)-2-[4-(4-methoxyphenyl)-1-oxo-2-phthalazinyl]acetamideCaenorhabditis elegansIC50100.000010
4-[[4-(benzenesulfonyl)-1-piperazinyl]-oxomethyl]-2-methyl-1-phthalazinoneCaenorhabditis elegansIC50100.000010
2-(4-benzofuro[3,2-d]pyrimidinylthio)-N-(2-ethoxyphenyl)acetamideCaenorhabditis elegansIC50100.000010
2-[2-(4-chlorophenoxy)ethylthio]pyrimidineCaenorhabditis elegansIC5056.186720
N-[4-(1-piperidinyl)phenyl]-2-quinolinecarboxamideCaenorhabditis elegansIC50100.000010
1H-indol-3-yl(pyridin-2-yl)methanolCaenorhabditis elegansIC50100.000010
2-[4-[[4-[bis(2-hydroxyethyl)amino]-2-chlorophenyl]-(2-chlorophenyl)methyl]-3-chloro-N-(2-hydroxyethyl)anilino]ethanolCaenorhabditis elegansIC50100.000010
[3-methyl-4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-thiophen-2-ylmethanoneCaenorhabditis elegansIC50100.000010
5-(2-nitrophenyl)-N-(2-thiazolyl)-2-furancarboxamideCaenorhabditis elegansIC50100.000010
3-[5-(dimethylsulfamoyl)-1-ethyl-2-benzimidazolyl]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)propanamideCaenorhabditis elegansIC50100.000010
N-[3-[(4-chlorophenyl)-oxomethyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-3-pyridinecarboxamideCaenorhabditis elegansIC50100.000010
2-[[2-(cyclohexylamino)-2-oxo-1-thiophen-2-ylethyl]-[1-oxo-2-[[oxo(thiophen-2-yl)methyl]amino]ethyl]amino]acetic acid ethyl esterCaenorhabditis elegansIC50100.000010
4-(2,3-dihydroindol-1-yl)-N-[3-(N-ethyl-3-methylanilino)propyl]-3-(1-imidazolyl)-4-oxobutanamideCaenorhabditis elegansIC50100.000010
N-(2,3-dihydro-1H-inden-5-yl)-2-[(4-hydroxy-6-oxo-1H-pyrimidin-2-yl)thio]acetamideCaenorhabditis elegansIC50100.000010
2-(6-benzimidazolo[1,2-c]quinazolinylthio)-N-(2-furanylmethyl)acetamideCaenorhabditis elegansIC50100.000010
3-(4-bromophenyl)-1H-pyrazole-5-carboxylic acid methyl esterCaenorhabditis elegansIC50100.000010
N-[2-(2-methyl-1-indolyl)ethyl]benzamideCaenorhabditis elegansIC50100.000010
1-[3-[4-(2-fluorophenyl)-1-piperazinyl]propyl]-3-[4-(methylthio)phenyl]ureaCaenorhabditis elegansIC50100.000010
2-(2-methoxyethyl)-9-methyl-1-oxo-N-(thiophen-2-ylmethyl)-4-pyrido[3,4-b]indolecarboxamideCaenorhabditis elegansIC50100.000010
N-(4-ethylphenyl)-5-(2-furanyl)-3-isoxazolecarboxamideCaenorhabditis elegansIC50100.000010
N-(3,4-dimethylphenyl)-5-(2-furanyl)-3-isoxazolecarboxamideCaenorhabditis elegansIC50100.000010
6,8-dibromo-2-thiophen-2-ylquinolineCaenorhabditis elegansIC50100.000010
2-(4-phenyl-1-piperazinyl)quinoxalineCaenorhabditis elegansIC5092.083320
1-(2-fluorophenyl)-3-(N-(phenylmethyl)anilino)thioureaCaenorhabditis elegansIC50100.000010
1-[(1,2-dimethyl-5-indolyl)methyl]-3-(phenylmethyl)thioureaCaenorhabditis elegansIC50100.000010
N-[4-[(1,2-dimethyl-5-indolyl)methylsulfamoyl]phenyl]acetamideCaenorhabditis elegansIC50100.000010
3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-4-(4-fluorophenyl)-1H-1,2,4-triazole-5-thioneCaenorhabditis elegansIC50100.000010
4-[(1,2-dimethyl-5-indolyl)methylamino]-4-oxobutanoic acidCaenorhabditis elegansIC50100.000010
N-[3-(2-methylcyclohexyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]-1,3-benzothiazol-2-amineCaenorhabditis elegansIC50100.000010
N-[2-(2-benzamidoethyl)-1-methyl-5-benzimidazolyl]-2-methoxybenzamideCaenorhabditis elegansIC50100.000010
N-[(1,2-dimethyl-5-indolyl)methyl]-2-(4-nitrophenyl)acetamideCaenorhabditis elegansIC50100.000010
styrylquinolineCaenorhabditis elegansIC5062.400020
N-(3,4-dichlorophenyl)-6-(1-imidazolyl)-3-pyridazinamineCaenorhabditis elegansIC50100.000010
5-methoxy-3,6-diphenyl-1,2,4-triazineCaenorhabditis elegansIC5052.435020
6-bromo-2-(1-pyrrolidinyl)-1,3-benzothiazoleCaenorhabditis elegansIC5052.625020
3-[(3-fluorophenyl)methylthio]-6-(2-furanyl)pyridazineCaenorhabditis elegansIC50100.000010
5-Chloro-3-pyridinyl 2-furoateCaenorhabditis elegansIC50100.000010
2-methyl-6-(phenylethynyl)pyridine hydrochlorideCaenorhabditis elegansIC50100.000010
amipriloseCaenorhabditis elegansIC50100.000010
2-bromo-5,6-dihydrodibenzo[3,1-[7]annulen-11-oneCaenorhabditis elegansIC5052.665020
(3aS,5S,9aS)-5-[1-(2-methoxyphenyl)-4-pyrazolyl]-2-phenyl-3a,4,5,7,8,9-hexahydro-3H-pyrrolo[3,4-h]pyrrolizin-1-oneCaenorhabditis elegansIC50100.000010
N-(5-chloro-2-pyridinyl)-4H-thieno[3,2-c][1]benzopyran-2-carboxamideCaenorhabditis elegansIC50100.000010