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3,4-methylenedioxyamphetamine and Sensitivity and Specificity

3,4-methylenedioxyamphetamine has been researched along with Sensitivity and Specificity in 28 studies

3,4-Methylenedioxyamphetamine: An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
" A total of 31 healthy Chinese subjects participated in the pharmacokinetic study of single bolus intravenous injection of piperphentonamine hydrochloride."2.77Determination of piperphentonamine and metabolites M1 and M6 in human plasma and urine by LC/MS/MS and its application in a pharmacokinetics study in Chinese healthy volunteers. ( Han, L; Hu, X; Li, J; Li, K; Li, R; Shi, A; Wan, H, 2012)
" The statistical distribution of the drug concentrations compared with the self-reported consumption behaviour of the users may possibly lead to a better understanding of the relationship between drug dosage and corresponding concentrations in hair."1.29Concentrations of delta 9-tetrahydrocannabinol, cocaine and 6-monoacetylmorphine in hair of drug abusers. ( Kauert, G; Röhrich, J, 1996)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (28.57)18.2507
2000's18 (64.29)29.6817
2010's2 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, J1
Xu, X1
Wang, C1
You, T1
Sergi, M1
Bafile, E1
Compagnone, D1
Curini, R1
D'Ascenzo, G1
Romolo, FS1
da Silva, DG1
de Pinho, PG1
Pontes, H1
Ferreira, L1
Branco, P1
Remião, F1
Carvalho, F1
Bastos, ML1
Carmo, H1
Shi, A1
Hu, X1
Li, K1
Li, J1
Han, L1
Wan, H1
Li, R1
Carter, JF1
Titterton, aE1
Murray, M1
Sleeman, R1
Murray, RA1
Doering, PL1
Boothby, LA1
Merves, ML1
McCusker, RR1
Chronister, CW1
Goldberger, BA1
Tsai, CH1
Fang, C1
Liu, JT1
Lin, CH1
Marchioro, L1
Bassetto, F1
Dall'Olio, G1
Tedeschi, L1
Castagna, F1
Plebani, M1
da Costa, JL1
da Matta Chasin, AA1
Laloup, M1
Tilman, G1
Maes, V1
De Boeck, G2
Wallemacq, P1
Ramaekers, J1
Samyn, N2
Peters, FT1
Lamers, CT1
Riedel, WJ1
Kraemer, T1
Maurer, HH1
Pirnay, SO1
Abraham, TT1
Huestis, MA1
Tomita, M1
Nakashima, MN1
Wada, M1
Nakashima, K1
Shima, N1
Kamata, H1
Katagi, M1
Tsuchihashi, H2
Sakuma, T1
Nemoto, N1
Poklis, A1
Fitzgerald, RL1
Hall, KV1
Saady, JJ1
Kauert, G1
Röhrich, J1
Pisternick, W1
Kovar, KA2
Ensslin, H1
Sadeghipour, F1
Veuthey, JL1
Keller, T1
Miki, A1
Regenscheit, P1
Dirnhofer, R1
Schneider, A1
Uotila, J1
Solakivi, T1
Jaakkola, O1
Tuimala, R1
Lehtimäki, T1
Hensley, D1
Cody, JT1
Ugland, HG1
Krogh, M1
Rasmussen, KE1
Borth, S1
Hänsel, W1
Rösner, P1
Junge, T1
Clauwaert, KM1
Van Bocxlaer, JF1
De Letter, EA1
Van Calenbergh, S1
Lambert, WE1
De Leenheer, AP1
Backofen, U1
Matysik, FM1
Hoffmann, W1
Lunte, CE1
Brunnenberg, M1
Pizarro, N1
Ortuño, J1
Farré, M1
Hernández-López, C1
Pujadas, M1
Llebaria, A1
Joglar, J1
Roset, PN1
Mas, M1
Segura, J1
Camí, J1
de la Torre, R1
Birnbaum, GE1
Reis, HT1

Trials

4 trials available for 3,4-methylenedioxyamphetamine and Sensitivity and Specificity

ArticleYear
Determination of piperphentonamine and metabolites M1 and M6 in human plasma and urine by LC/MS/MS and its application in a pharmacokinetics study in Chinese healthy volunteers.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Nov-01, Volume: 908

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Cardiovascular Agents; Chromatography, High Pressu

2012
Validation of an ELISA-based screening assay for the detection of amphetamine, MDMA and MDA in blood and oral fluid.
    Forensic science international, 2005, Oct-04, Volume: 153, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, Liquid; Dose-Response Relationship, Drug

2005
Antibodies against copper-oxidised and malondialdehyde-modified low density lipoproteins in pre-eclampsia pregnancies.
    British journal of obstetrics and gynaecology, 1998, Volume: 105, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Autoantibodies; Copper; Female; Gestational Age; Humans; Lipop

1998
Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis.
    Journal of analytical toxicology, 2002, Volume: 26, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Deoxyepinephrine; Electrophoresis, Capillary; Gas Chromatography-Mass

2002

Other Studies

24 other studies available for 3,4-methylenedioxyamphetamine and Sensitivity and Specificity

ArticleYear
Analysis of amphetamines in urine with liquid-liquid extraction by capillary electrophoresis with simultaneous electrochemical and electrochemiluminescence detection.
    Electrophoresis, 2008, Volume: 29, Issue:19

    Topics: 2,2'-Dipyridyl; 3,4-Methylenedioxyamphetamine; Amphetamines; Electrochemical Techniques; Electrophor

2008
Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS.
    Analytical and bioanalytical chemistry, 2009, Volume: 393, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Body Fluids; Calibration; Chromatography, High Pressure

2009
Gas chromatography-ion trap mass spectrometry method for the simultaneous measurement of MDMA (ecstasy) and its metabolites, MDA, HMA, and HMMA in plasma and urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Mar-15, Volume: 878, Issue:9-10

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Dopamine; Gas Chromatography-Mass Spectrometry; Male; Metham

2010
Isotopic characterisation of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethylamphetamine (ecstasy).
    The Analyst, 2002, Volume: 127, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Drug and Narcotic Control; Gas Chromatography-Mass Spectrometry; Illi

2002
Putting an Ecstasy test kit to the test: harm reduction or harm induction?
    Pharmacotherapy, 2003, Volume: 23, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reagent Kits, Diagnostic; Rep

2003
Stacking and low-temperature technique in nonaqueous capillary electrophoresis for the analysis of 3,4-methylenedioxymethamphetamine.
    Electrophoresis, 2004, Volume: 25, Issue:10-11

    Topics: 3,4-Methylenedioxyamphetamine; Electrophoresis, Capillary; Sensitivity and Specificity; Spectrophoto

2004
Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): evaluation of KIMS (kinetic interaction of microparticles in solution) assay at two cut-off levels.
    Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Amphetamines; Chromatography, High Pressure Liquid

2004
Determination of MDMA, MDEA and MDA in urine by high performance liquid chromatography with fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Nov-05, Volume: 811, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Forensic Medicine; Humans; N-Me

2004
Drug testing in blood: validated negative-ion chemical ionization gas chromatographic-mass spectrometric assay for enantioselective measurement of the designer drugs MDEA, MDMA, and MDA and its application to samples from a controlled study with MDMA.
    Clinical chemistry, 2005, Volume: 51, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometr

2005
Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine.
    Clinical chemistry, 2006, Volume: 52, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Calibration; Central Nervous System Stimulants; Dopamin

2006
Sensitive determination of MDMA and its metabolite MDA in rat blood and brain microdialysates by HPLC with fluorescence detection.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Benzoates; Blood Chemical Analysis; Brain Chemistry; Calibra

2007
Direct determination of glucuronide and sulfate of 4-hydroxy-3-methoxymethamphetamine, the main metabolite of MDMA, in human urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Sep-15, Volume: 857, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine-Related Disorders; Calibration; Designer Drugs; Gas Chrom

2007
EMIT-d.a.u. monoclonal amphetamine/methamphetamine assay. II. Detection of methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA).
    Forensic science international, 1993, Volume: 59, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Cross Reactions; Designer Drugs; Gas Chromatogr

1993
Concentrations of delta 9-tetrahydrocannabinol, cocaine and 6-monoacetylmorphine in hair of drug abusers.
    International journal of legal medicine, 1996, Volume: 108, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Accidents, Traffic; Amphetamine; Cocaine; Crime; Designer Drugs; Dron

1996
High-performance thin-layer chromatographic determination of N-ethyl-3,4-methylenedioxyamphetamine and its major metabolites in urine and comparison with high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Jan-10, Volume: 688, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Calibration; Chromatography, High Pressure Liquid; Chromatography, Th

1997
Sensitive and selective determination of methylenedioxylated amphetamines by high-performance liquid chromatography with fluorimetric detection.
    Journal of chromatography. A, 1997, Nov-07, Volume: 787, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, High Pressure Liquid; Humans; N-Methyl-

1997
Detection of designer drugs in human hair by ion mobility spectrometry (IMS).
    Forensic science international, 1998, Jun-08, Volume: 94, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Forensic Medicine; Hair; Hallucinogens; Humans; N-Met

1998
Simultaneous determination of amphetamine, methamphetamine, methylenedioxyamphetamine (MDA), methylenedioxymethamphetamine (MDMA), and methylenedioxyethylamphetamine (MDEA) enantiomers by GC-MS.
    Journal of analytical toxicology, 1999, Volume: 23, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Central Nervous System Stimulants; Gas Chromatography-M

1999
Automated determination of 'Ecstasy' and amphetamines in urine by SPME and capillary gas chromatography after propylchloroformate derivatisation.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 19, Issue:3-4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Esters; Evaluation Studies as Topic; Fo

1999
Synthesis of 2,3- and 3,4-methylenedioxyphenylalkylamines and their regioisomeric differentiation by mass spectral analysis using GC-MS-MS.
    Forensic science international, 2000, Dec-11, Volume: 114, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Central Nervous System Stimulants; Designer Drugs; Gas Chromatography

2000
Determination of the designer drugs 3, 4-methylenedioxymethamphetamine, 3,4-methylenedioxyethylamphetamine, and 3,4-methylenedioxyamphetamine with HPLC and fluorescence detection in whole blood, serum, vitreous humor, and urine.
    Clinical chemistry, 2000, Volume: 46, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Designer Drugs; Humans

2000
Analysis of illicit drugs by nonaqueous capillary electrophoresis and electrochemical detection.
    Fresenius' journal of analytical chemistry, 2000, Volume: 367, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Acetonitriles; Amphetamines; Cocaine; Electrophoresis, Capillary; Hal

2000
Stereospecific analysis of ecstasy-like N-ethyl-3,4-methylenedioxyamphetamine and its metabolites in humans.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Feb-10, Volume: 751, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Humans; N-Methyl-3,4-methylened

2001
Women's sexual working models: an evolutionary-attachment perspective.
    Journal of sex research, 2006, Volume: 43, Issue:4

    Topics: Adult; Aged; Female; Humans; Interpersonal Relations; Love; Middle Aged; Models, Psychological; Pers

2006