A thioredoxin reductase 1, cytoplasmic that is encoded in the genome of rat. [OMA:O89049, PRO:DNx]
TR;
EC 1.8.1.9;
NADPH-dependent thioredoxin reductase;
Thioredoxin reductase TR1
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 4-phenyl-3-furoxancarbonitrile | Rattus norvegicus (Norway rat) | IC50 | 400.0000 | 1 | 1 |
| cyclobutane-1,1-dicarboxylic acid | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| danthron | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| hypericin | Rattus norvegicus (Norway rat) | IC50 | 178.0625 | 1 | 2 |
| 1,4-dihydroxyanthraquinone | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| anthrone | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| rhein | Rattus norvegicus (Norway rat) | IC50 | 84.0000 | 1 | 1 |
| aloe emodin | Rattus norvegicus (Norway rat) | IC50 | 180.0000 | 1 | 1 |
| chrysophanic acid | Rattus norvegicus (Norway rat) | IC50 | 194.0000 | 1 | 1 |
| physcione | Rattus norvegicus (Norway rat) | IC50 | 185.0000 | 1 | 1 |
| methylnaphthazarin | Rattus norvegicus (Norway rat) | IC50 | 0.7000 | 1 | 1 |
| chalcone | Rattus norvegicus (Norway rat) | IC50 | 36.5500 | 2 | 2 |
| manumycin | Rattus norvegicus (Norway rat) | IC50 | 0.8100 | 3 | 3 |
| alloin | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| (1,2-bis(1,2-benzisoselenazolone-3(2h)-ketone))ethane | Rattus norvegicus (Norway rat) | IC50 | 6.0000 | 1 | 1 |