flurbiprofen has been researched along with Sensitivity and Specificity in 13 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flurbiprofen (FLB) is one of the phenylalkanoic acid derivatives of non-steroidal anti-inflammatory drugs used for the management of pain and inflammation in patients with arthritis." | 3.80 | Simultaneous determination of flurbiprofen and its hydroxy metabolite in human plasma by liquid chromatography-tandem mass spectrometry for clinical application. ( Byeon, JY; Choi, CI; Jang, CG; Kim, SH; Kim, YH; Lee, HI; Lee, JE; Lee, SY; Lee, YJ; Park, SY, 2014) |
| "Flufenamic acid was selected as internal standard." | 1.35 | Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative. ( Chiap, P; Crommen, J; Fillet, M; Ivanyi, R; Rousseau, A; Servais, AC, 2008) |
| " After strict validation, the method indicated good performance in terms of reproducibility, specificity, linearity, precision and accuracy, and it was successfully applied to the pharmacokinetic study of flurbiprofen in rats after oral and transdermal administration." | 1.35 | Cloud point extraction-HPLC method for determination and pharmacokinetic study of flurbiprofen in rat plasma after oral and transdermal administration. ( Han, F; Jia, Q; Li, SM; Liu, HZ; Shi, XL; Xu, L; Yao, HM; Yin, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, HI | 1 |
| Choi, CI | 1 |
| Byeon, JY | 1 |
| Lee, JE | 1 |
| Park, SY | 1 |
| Kim, YH | 1 |
| Kim, SH | 1 |
| Lee, YJ | 1 |
| Jang, CG | 1 |
| Lee, SY | 1 |
| Rousseau, A | 2 |
| Chiap, P | 2 |
| Ivanyi, R | 2 |
| Crommen, J | 2 |
| Fillet, M | 2 |
| Servais, AC | 2 |
| Pedrini, M | 1 |
| Prokhorova, AF | 1 |
| Shapovalova, EN | 1 |
| Shpak, AV | 1 |
| Staroverov, SM | 1 |
| Shpigun, OA | 1 |
| Ali, I | 1 |
| Hussain, I | 1 |
| Saleem, K | 1 |
| Aboul-Enein, HY | 1 |
| Péhourcq, F | 2 |
| Matoga, M | 1 |
| Jarry, C | 2 |
| Bannwarth, B | 2 |
| Jerdi, MC | 1 |
| Daali, Y | 1 |
| Oestreicher, MK | 1 |
| Cherkaoui, S | 1 |
| Dayer, P | 1 |
| Han, F | 1 |
| Yin, R | 1 |
| Shi, XL | 1 |
| Jia, Q | 1 |
| Liu, HZ | 1 |
| Yao, HM | 1 |
| Xu, L | 1 |
| Li, SM | 1 |
| Riegel, M | 1 |
| Ellis, PP | 1 |
| Neupert, W | 1 |
| Oelkers, R | 1 |
| Brune, K | 1 |
| Geisslinger, G | 1 |
| Dhavse, VV | 1 |
| Parmar, DV | 1 |
| Devarajan, PV | 1 |
| Hutzler, JM | 1 |
| Frye, RF | 1 |
| Tracy, TS | 1 |
1 trial available for flurbiprofen and Sensitivity and Specificity
| Article | Year |
|---|---|
High-performance thin-layer chromatographic determination of flurbiprofen in plasma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chromatography, Thin Layer; Flurbiprofen; | 1997 |
12 other studies available for flurbiprofen and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous determination of flurbiprofen and its hydroxy metabolite in human plasma by liquid chromatography-tandem mass spectrometry for clinical application.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Chromatography, High Pressure Liquid; Flurbiprof | 2014 |
Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative.
Topics: Calibration; Cyclodextrins; Drug Contamination; Electrophoresis, Capillary; Flufenamic Acid; Flurbip | 2008 |
Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in nonaqueous capillary electrophoresis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Precipitation; Electrophoresis, Capillary; Flurbip | 2008 |
Enantiorecognition of profens by capillary electrophoresis using a novel chiral selector eremomycin.
Topics: Chromatography, High Pressure Liquid; Electrolytes; Electrophoresis, Capillary; Flurbiprofen; Glycop | 2009 |
Enantiomeric resolution of ibuprofen and flurbiprofen in human plasma by SPE-chiral HPLC methods.
Topics: Analgesics; Chromatography, High Pressure Liquid; Flurbiprofen; Humans; Ibuprofen; Sensitivity and S | 2012 |
HPLC microdetermination of flurbiprofen enantiomers in plasma with a glycopeptide-type chiral stationary phase column.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Flurbiprofen; Glycope | 2004 |
A simplified analytical method for a phenotyping cocktail of major CYP450 biotransformation routes.
Topics: Biotransformation; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; D | 2004 |
Cloud point extraction-HPLC method for determination and pharmacokinetic study of flurbiprofen in rat plasma after oral and transdermal administration.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pr | 2008 |
High-performance liquid chromatographic assay for antiinflammatory agents diclofenac and flurbiprofen in ocular fluids.
Topics: Animals; Aqueous Humor; Cataract Extraction; Chromatography, High Pressure Liquid; Diclofenac; Flurb | 1994 |
A new reliable chemiluminescence immunoassay (CLIA) for prostaglandin E2 using enhanced luminol as substrate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blister; Dinoprostone; Evaluation Studies as Topic | 1996 |
Sensitive and specific high-performance liquid chromatographic assay for 4'-hydroxyflurbiprofen and flurbiprofen in human urine and plasma.
Topics: Aryl Hydrocarbon Hydroxylases; Calibration; Chromatography, High Pressure Liquid; Cytochrome P-450 C | 2000 |
Chiral resolution of flurbiprofen and ketoprofen enantiomers by HPLC on a glycopeptide-type column chiral stationary phase.
Topics: Buffers; Chromatography, High Pressure Liquid; Drug Stability; Flurbiprofen; Furans; Glycopeptides; | 2001 |