Solute carrier organic anion transporter family member 4A1

A solute carrier organic anion transporter family member 4A1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q96BD0]

Synonyms

OATP4A1;
Colon organic anion transporter;
Organic anion transporter polypeptide-related protein 1;
OATP-RP1;
OATPRP1;
POAT;
Organic anion-transporting polypeptide E;
OATP-E;
Sodium-independent organic anion transporter E;<

Research

Bioassay Publications (1)

Timeframe	Studies on this Protein(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Compounds (2)

Drugs with Other Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
triiodothyronine	Homo sapiens (human)	Km	0.9000	1	1
taurocholic acid	Homo sapiens (human)	Km	14.9000	1	1

Enables

This protein enables 5 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
organic anion transmembrane transporter activity	molecular function	Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. [GOC:ai]
prostaglandin transmembrane transporter activity	molecular function	Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities. [GOC:ai]
sodium-independent organic anion transmembrane transporter activity	molecular function	Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner. [GOC:go_curators]
thyroid hormone transmembrane transporter activity	molecular function	Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. [GOC:ai]

Located In

This protein is located in 1 target(s):

Target	Category	Definition
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

Active In

This protein is active in 1 target(s):

Target	Category	Definition
basolateral plasma membrane	cellular component	The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators]

Involved In

This protein is involved in 5 target(s):

Target	Category	Definition
monoatomic ion transport	biological process	The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. [GOC:ai]
prostaglandin transport	biological process	The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]
transmembrane transport	biological process	The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. [GOC:dph, GOC:jid]
thyroid hormone transport	biological process	The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:rph]
sodium-independent organic anion transport	biological process	The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:go_curators]