Page last updated: 2024-08-07 13:14:48
Metabotropic glutamate receptor 7
A metabotropic glutamate receptor 7 that is encoded in the genome of rat. [OMA:P35400, PRO:DNx]
Synonyms
mGluR7
Research
Bioassay Publications (12)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (17)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| harmalan | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| 1-methyl-6-methoxy-dihydro-beta-carboline | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| harmine | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| ly 341495 | Rattus norvegicus (Norway rat) | Ki | 0.1100 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| d-glutamate | Rattus norvegicus (Norway rat) | EC50 | 5,400.0000 | 1 | 1 |
| glutamic acid | Rattus norvegicus (Norway rat) | EC50 | 800.0000 | 2 | 3 |
| quisqualic acid | Rattus norvegicus (Norway rat) | EC50 | 1,000.0000 | 1 | 1 |
| plasmenylserine | Rattus norvegicus (Norway rat) | EC50 | 160.0000 | 1 | 1 |
| 1-amino-1,3-dicarboxycyclopentane | Rattus norvegicus (Norway rat) | EC50 | 1,000.0000 | 1 | 1 |
| 2-amino-4-phosphonobutyric acid | Rattus norvegicus (Norway rat) | EC50 | 316.4889 | 8 | 9 |
| vu0155094 | Rattus norvegicus (Norway rat) | EC50 | 1.5000 | 2 | 2 |
| l-2-(carboxypropyl)glycine | Rattus norvegicus (Norway rat) | EC50 | 47.0000 | 1 | 1 |
| 2-(2,3-dicarboxycyclopropyl)glycine | Rattus norvegicus (Norway rat) | EC50 | 40.0000 | 1 | 1 |
| 1-aminocyclopentane-1,3,4-tricarboxylic acid | Rattus norvegicus (Norway rat) | EC50 | 740.0000 | 2 | 2 |
| 3,4-dicarboxyphenylglycine | Rattus norvegicus (Norway rat) | EC50 | 100.0000 | 1 | 1 |
| 5-methyl-n-(4-methylpyrimidin-2-yl)-4-(1h-pyrazol-4-yl)thiazol-2-amine | Rattus norvegicus (Norway rat) | EC50 | 10.0000 | 1 | 1 |
| vu0422288 | Rattus norvegicus (Norway rat) | EC50 | 0.1460 | 2 | 2 |