Page last updated: 2024-12-11

zeatin riboside

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

zeatin riboside: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

9-ribosyl-trans-zeatin : A 9-ribosylzeatin having trans-zeatin as the nucleobase. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID6440982
CHEBI ID71693
SCHEMBL ID4058989
MeSH IDM0054611

Synonyms (60)

Synonym
7lg4d082a9 ,
(e)-n-(4-hydroxy-3-methyl-2-butenyl)adenosine
adenosine, n-(4-hydroxy-3-methyl-2-butenyl)-, (e)-
unii-7lg4d082a9
trans-zeatin-riboside ,
trans-zeatin riboside
UPCMLD-DP150:001
trans-zeatin-riboside, bioreagent, plant cell culture tested, ~95%
trans-zeatin-riboside, ~95%
UPCMLD-DP150
UPCMLD-DP150:002
NCGC00161675-01
c15h21n5o5
zeatin riboside
adenosine, n-(4-hydroxy-3-methyl-2-butenyl)-
n-(4-hydroxy-3-methyl-2-butenyl)adenosine
ribosylzeatin
Z-3000
6025-53-2
17493EE6-B91F-4EAF-901B-25B5904BCD54
zeatin, 9-beta-ribofuranosyl-, trans-
28542-78-1
(2r,3s,4r,5r)-2-(hydroxymethyl)-5-[6-[[(e)-4-hydroxy-3-methylbut-2-enyl]amino]purin-9-yl]oxolane-3,4-diol
(3r,4s,5r)-2-(((e)-4-((7h-purin-6-yl)amino)-2-methylbut-2-en-1-yl)oxy)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;trans-zeatinriboside
A832655
AKOS016003311
trans-zeatinriboside
9-beta-d-ribofuranosyl-trans-zeatin
9-ribosyl-trans-zeatin
trans-zeatin 9-beta-d-ribofuranoside
n-[(2e)-4-hydroxy-3-methylbut-2-en-1-yl]adenosine
CHEBI:71693
9-beta-d-ribosyl-trans-zeatin
n6-(trans-4-hydroxy-3-methyl-2-buten-1-yl)adenosine
9-(beta-d-ribofuranosyl)-trans-zeatin
S5678
SCHEMBL4058989
6-[(e)-4-hydroxy-3-methylbut-2-enylamino]-9-beta-d-ribofuranosylpurine, 97%
zeatin 9-.beta.-ribonucleoside
9-.beta.-d-ribofuranosylzeatin
ribosyl-trans-zeatin
zeatin ribonucleoside
GOSWTRUMMSCNCW-HNNGNKQASA-N
AC-32196
(2r,3r,4s,5r)-2-(6-(((e)-4-hydroxy-3-methylbut-2-en-1-yl)amino)-9h-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
mfcd00036809
adenosine, n-[(2e)-4-hydroxy-3-methyl-2-butenyl]-
6-(4-hydroxy-3-methyl-2-butenylamino)-9-d-ribofuranosylpurine
Q27139815
HY-W011151
DS-11490
n-((2e)-4-hydroxy-3-methylbut-2-en-1-yl)adenosine
DTXSID101017776
CS-W011867
tzr
CCG-268042
(2r,3r,4s,5r)-2-(6-((4-hydroxy-3-methylbut-2-en-1-yl)amino)-9h-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
q3v ,
adenosine, n-[(2e)-4-hydroxy-3-methyl-2-buten-1-yl]- [
(2r,3r,4s,5r)-2-(6-{[(2e)-4-hydroxy-3-methylbut-2-en-1-yl]amino}-9h-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Research Excerpts

Treatment

ExcerptReferenceRelevance
"Zeatin riboside treatment also potently inhibits thioglycollate-induced peritoneal leukocytosis."( The plant hormone zeatin riboside inhibits T lymphocyte activity via adenosine A2A receptor activation.
Lappas, CM, 2015
)
1.47

Dosage Studied

ExcerptRelevanceReference
" The investigation of gene dosage effects in homozygote plants readdresses the question of threshold levels for cytokinin effects on the developmental program of plants."( Promoter tagging with a promoterless ipt gene leads to cytokinin-induced phenotypic variability in transgenic tobacco plants:implications of gene dosage effects.
Hewelt, A; Prinsen, E; Schell, J; Schmülling, T; Van Onckelen, H, 1994
)
0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
cytokininA phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
nucleoside analogueAn analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells.
9-ribosylzeatinAn N-glycosylzeatin that is zeatin in which the hydrogen attached to the nitrogen at position 9 of the adenine moiety is replaced by a beta-D-ribofuranosyl group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (6)

PathwayProteinsCompounds
Regulation of leaf development1722
Cytokinins Degradation113
cytokinins degradation114
Gravitropism under normal or artificial gravity environments5811
Regulation of lemma joints development and leaf angle by cytokinin111
cytokinins degradation519
Responses to stimuli: abiotic stimuli and stresses9526
Trans-zeatin biosynthesis022

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (87)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (8.05)18.7374
1990's8 (9.20)18.2507
2000's23 (26.44)29.6817
2010's41 (47.13)24.3611
2020's8 (9.20)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 26.17

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index26.17 (24.57)
Research Supply Index4.55 (2.92)
Research Growth Index4.94 (4.65)
Search Engine Demand Index31.58 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (26.17)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (2.13%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other92 (97.87%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]