| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted
[description not available] | 0 | 6.86 | 5 | 1 |
Hepatitis C
INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown. | 0 | 6.86 | 5 | 1 |
Idiopathic Parkinson Disease
[description not available] | 0 | 2.25 | 1 | 0 |
Parkinson Disease
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) | 0 | 2.25 | 1 | 0 |
Encephalopathy, Traumatic
[description not available] | 0 | 2.31 | 1 | 0 |
Brain Injuries, Traumatic
A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain. | 0 | 2.31 | 1 | 0 |
Injury, Ischemia-Reperfusion
[description not available] | 0 | 3.59 | 8 | 0 |
Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 3.59 | 8 | 0 |
Brain Disorders
[description not available] | 0 | 2.15 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 3.57 | 8 | 0 |
Asystole
[description not available] | 0 | 2.5 | 2 | 0 |
Symptom Cluster
[description not available] | 0 | 2.15 | 1 | 0 |
Brain Diseases
Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. | 0 | 2.15 | 1 | 0 |
Heart Arrest
Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation. | 0 | 2.5 | 2 | 0 |
Syndrome
A characteristic symptom complex. | 0 | 2.15 | 1 | 0 |
Benign Neoplasms, Brain
[description not available] | 0 | 2.15 | 1 | 0 |
Astrocytoma, Grade IV
[description not available] | 0 | 2.15 | 1 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 2.15 | 1 | 0 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 2.15 | 1 | 0 |
Allergic Encephalomyelitis
[description not available] | 0 | 2.15 | 1 | 0 |
Injuries, Spinal Cord
[description not available] | 0 | 2.75 | 3 | 0 |
Spinal Cord Injuries
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.). | 0 | 2.75 | 3 | 0 |
Mesenteric Vascular Occlusion
Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6) | 0 | 2.08 | 1 | 0 |
Cardiovascular Stroke
[description not available] | 0 | 3.14 | 5 | 0 |
Injury, Myocardial Reperfusion
[description not available] | 0 | 3.43 | 7 | 0 |
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 3.14 | 5 | 0 |
Hyperoxaluria
Excretion of an excessive amount of OXALATES in the urine. | 0 | 2.1 | 1 | 0 |
Cardiovascular Diseases
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 3.01 | 1 | 0 |
Muscular Dystrophy
[description not available] | 0 | 2.1 | 1 | 0 |
Muscular Dystrophies
A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS. | 0 | 2.1 | 1 | 0 |
Acute Kidney Failure
[description not available] | 0 | 2.1 | 1 | 0 |
Rhabdomyolysis
Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. | 0 | 2.1 | 1 | 0 |
Acute Kidney Injury
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 2.1 | 1 | 0 |
Apoplexy
[description not available] | 0 | 2.1 | 1 | 0 |
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810) | 0 | 2.1 | 1 | 0 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 2.13 | 1 | 0 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 2.13 | 1 | 0 |
Infarct
[description not available] | 0 | 2.04 | 1 | 0 |
Bile Duct Obstruction
[description not available] | 0 | 2.04 | 1 | 0 |
Cirrhosis
[description not available] | 0 | 2.04 | 1 | 0 |
Cholestasis
Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS). | 0 | 2.04 | 1 | 0 |
Fibrosis
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. | 0 | 2.04 | 1 | 0 |
Atherogenesis
[description not available] | 0 | 2.05 | 1 | 0 |
Atherosclerosis
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 2.05 | 1 | 0 |
Recrudescence
[description not available] | 0 | 2.05 | 1 | 0 |
Biliary Cirrhosis
[description not available] | 0 | 3.39 | 2 | 0 |
Liver Cirrhosis, Biliary
FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes. | 0 | 3.39 | 2 | 0 |
Electron Transport Chain Deficiencies, Mitochondrial
[description not available] | 0 | 2.74 | 3 | 0 |
Mitochondrial Diseases
Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes. | 0 | 2.74 | 3 | 0 |
Cirrhoses, Experimental Liver
[description not available] | 0 | 2.06 | 1 | 0 |
Acute Brain Injuries
[description not available] | 0 | 2.75 | 3 | 0 |
Brain Injuries
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits. | 0 | 2.75 | 3 | 0 |
Asthma, Bronchial
[description not available] | 0 | 2.06 | 1 | 0 |
Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). | 0 | 2.06 | 1 | 0 |
Acute Hepatic Failure
[description not available] | 0 | 2.06 | 1 | 0 |
Liver Failure, Acute
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C. | 0 | 2.06 | 1 | 0 |
Alloxan Diabetes
[description not available] | 0 | 2.07 | 1 | 0 |
Cardiac Remodeling, Ventricular
[description not available] | 0 | 2.07 | 1 | 0 |
Carditis
[description not available] | 0 | 2.07 | 1 | 0 |
Coxsackie Virus Infections
[description not available] | 0 | 2.07 | 1 | 0 |
Endomyocardial Fibrosis
A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE). | 0 | 2.07 | 1 | 0 |
Myocarditis
Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies. | 0 | 2.07 | 1 | 0 |
Anoxemia
[description not available] | 0 | 2.07 | 1 | 0 |
Hypoxia
Sub-optimal OXYGEN levels in the ambient air of living organisms. | 0 | 2.07 | 1 | 0 |
Autoimmune Chronic Hepatitis
[description not available] | 0 | 3 | 1 | 0 |
Hepatitis, Autoimmune
A chronic self-perpetuating hepatocellular INFLAMMATION of unknown cause, usually with HYPERGAMMAGLOBULINEMIA and serum AUTOANTIBODIES. | 0 | 3 | 1 | 0 |
Coronary Heart Disease
[description not available] | 0 | 2.02 | 1 | 0 |
Heart Disease, Ischemic
[description not available] | 0 | 2.02 | 1 | 0 |
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 2.02 | 1 | 0 |
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 2.72 | 3 | 0 |
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION). | 0 | 2.02 | 1 | 0 |
B16 Melanoma
[description not available] | 0 | 2.02 | 1 | 0 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 2.03 | 1 | 0 |
Bruise
[description not available] | 0 | 2.03 | 1 | 0 |
Contusions
Injuries resulting in hemorrhage, usually manifested in the skin. | 0 | 2.03 | 1 | 0 |
Bilirubinemia
[description not available] | 0 | 2.03 | 1 | 0 |
Anterior Cerebral Circulation Infarction
[description not available] | 0 | 2.03 | 1 | 0 |
Cerebral Ischemia
[description not available] | 0 | 2.03 | 1 | 0 |
Nerve Degeneration
Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways. | 0 | 2.03 | 1 | 0 |
Brain Ischemia
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. | 0 | 2.03 | 1 | 0 |
Brain Infarction
Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis. | 0 | 2.03 | 1 | 0 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 2.04 | 1 | 0 |
HIV
Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. | 0 | 1.99 | 1 | 0 |
HIV Coinfection
[description not available] | 0 | 1.99 | 1 | 0 |
HIV Infections
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 1.99 | 1 | 0 |