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ethacrynic acid and Sensitivity and Specificity

ethacrynic acid has been researched along with Sensitivity and Specificity in 4 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, FH1
Chiang, YR1
Tseng, AL1
Sung, YC1
Lu, J1
Huang, MC1
Ma, N1
Lee, HC1
Habdous, M1
Vincent-Viry, M1
Visvikis, S1
Siest, G1
Simic, T1
Pljesa-Ercegovac, M1
Savic-Radojevic, A1
Hadziahmetovic, M1
Mimic-Oka, J1
Voith, B1
Spahn-Langguth, H1
Mutschler, E1

Other Studies

4 other studies available for ethacrynic acid and Sensitivity and Specificity

ArticleYear
Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Algorithms; Colorectal Neoplasms; Drug Repositioning; Epistasis, Genetic; Ethacrynic

2014
Rapid spectrophotometric method for serum glutathione S-transferases activity.
    Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 326, Issue:1-2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Child; Child, Preschool; Dinitrochlorobenzene; Enzyme Inhibi

2002
Identification of a glutathione S-transferase without affinity for glutathione sepharose in human kidney.
    Amino acids, 2006, Volume: 30, Issue:4

    Topics: Chemical Phenomena; Chemistry, Physical; Chromatography, Affinity; Chromatography, Agarose; Electrop

2006
New specific and sensitive HPLC-assays for ethacrynic acid and its main metabolite--the cysteine conjugate--in biological material.
    Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:11

    Topics: Chromatography, High Pressure Liquid; Cysteine; Diuretics; Drug Stability; Ethacrynic Acid; Humans;

1995