ethacrynic acid has been researched along with Sensitivity and Specificity in 4 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chung, FH | 1 |
Chiang, YR | 1 |
Tseng, AL | 1 |
Sung, YC | 1 |
Lu, J | 1 |
Huang, MC | 1 |
Ma, N | 1 |
Lee, HC | 1 |
Habdous, M | 1 |
Vincent-Viry, M | 1 |
Visvikis, S | 1 |
Siest, G | 1 |
Simic, T | 1 |
Pljesa-Ercegovac, M | 1 |
Savic-Radojevic, A | 1 |
Hadziahmetovic, M | 1 |
Mimic-Oka, J | 1 |
Voith, B | 1 |
Spahn-Langguth, H | 1 |
Mutschler, E | 1 |
4 other studies available for ethacrynic acid and Sensitivity and Specificity
Article | Year |
---|---|
Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma.
Topics: Adenocarcinoma; Algorithms; Colorectal Neoplasms; Drug Repositioning; Epistasis, Genetic; Ethacrynic | 2014 |
Rapid spectrophotometric method for serum glutathione S-transferases activity.
Topics: Acetaminophen; Adolescent; Adult; Aged; Child; Child, Preschool; Dinitrochlorobenzene; Enzyme Inhibi | 2002 |
Identification of a glutathione S-transferase without affinity for glutathione sepharose in human kidney.
Topics: Chemical Phenomena; Chemistry, Physical; Chromatography, Affinity; Chromatography, Agarose; Electrop | 2006 |
New specific and sensitive HPLC-assays for ethacrynic acid and its main metabolite--the cysteine conjugate--in biological material.
Topics: Chromatography, High Pressure Liquid; Cysteine; Diuretics; Drug Stability; Ethacrynic Acid; Humans; | 1995 |