A sodium/hydrogen exchanger 3 that is encoded in the genome of rat. [OMA:P26433, PRO:DNx]
Na(+)/H(+) exchanger 3;
NHE-3;
Solute carrier family 9 member 3
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 5-dimethylamiloride | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 0 |
| 5-dimethylamiloride | Rattus norvegicus (Norway rat) | Ki | 14.0000 | 2 | 0 |
| 5-(n,n-hexamethylene)amiloride | Rattus norvegicus (Norway rat) | Ki | 2.4000 | 2 | 0 |
| ethylisopropylamiloride | Rattus norvegicus (Norway rat) | IC50 | 2.4000 | 1 | 0 |
| ethylisopropylamiloride | Rattus norvegicus (Norway rat) | Ki | 2.4000 | 2 | 0 |
| amiloride | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 0 |
| amiloride | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 2 | 0 |
| zoniporide | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 3 | 0 |
| tenapanor | Rattus norvegicus (Norway rat) | IC50 | 0.0115 | 3 | 1 |