Page last updated: 2024-08-07 14:39:44
NS3 protease
[no definition available]
Synonyms
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| telaprevir | | Km | 262.6667 | 3 | 3 |
Achiral pyrazinone-based inhibitors of the hepatitis C virus NS3 protease and drug-resistant variants with elongated substituents directed toward the S2 pocket.Journal of medicinal chemistry, , Mar-13, Volume: 57, Issue:5, 2014
Phenotypic characterization of resistant Val36 variants of hepatitis C virus NS3-4A serine protease.Antimicrobial agents and chemotherapy, , Volume: 52, Issue:1, 2008
Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha.The Journal of biological chemistry, , Aug-03, Volume: 282, Issue:31, 2007