[no definition available]
LTC4 synthase;
EC 4.4.1.20;
Glutathione S-transferase LTC4;
2.5.1.-;
Leukotriene-C(4) synthase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| imatinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| staurosporine | Cavia porcellus (domestic guinea pig) | Kd | 3.5000 | 1 | 1 |
| gefitinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| lestaurtinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| vatalanib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| ruboxistaurin | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| canertinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| birb 796 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| sb 203580 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| enzastaurin | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| erlotinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| lapatinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| sorafenib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| pd 173955 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| s 1033 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| bms 387032 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| tandutinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| vx-745 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| dasatinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| zd 6474 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| alvocidib | Cavia porcellus (domestic guinea pig) | Kd | 1.2000 | 1 | 1 |
| bosutinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| su 11248 | Cavia porcellus (domestic guinea pig) | Kd | 0.9300 | 1 | 1 |
| vx680 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| axitinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| pd 184352 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| bms345541 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| midostaurin | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| ki 20227 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| pi103 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| hki 272 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| tofacitinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| n-(6-chloro-7-methoxy-9h-beta-carbolin-8-yl)-2-methylnicotinamide | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| cediranib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| masitinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| pazopanib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| azd 6244 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| su 14813 | Cavia porcellus (domestic guinea pig) | Kd | 1.0000 | 1 | 1 |
| bibw 2992 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| tg100-115 | Cavia porcellus (domestic guinea pig) | Kd | 5.7000 | 1 | 1 |
| pha 665752 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| brivanib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| at 7519 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| bi 2536 | Cavia porcellus (domestic guinea pig) | Kd | 4.5000 | 1 | 1 |
| nvp-ast487 | Cavia porcellus (domestic guinea pig) | Kd | 1.0000 | 1 | 1 |
| kw 2449 | Cavia porcellus (domestic guinea pig) | Kd | 1.2000 | 1 | 1 |
| abt 869 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| gw 2580 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| crizotinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| chir-265 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| motesanib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| mln8054 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| GDC-0879 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| gsk 461364 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| azd 1152-hqpa | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| nvp-tae684 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| fedratinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| gsk690693 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| gdc 0941 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| plx 4720 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| sgx 523 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| quizartinib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| incb-018424 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| gsk 1838705a | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| gsk 1363089 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| chir 258 | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| nintedanib | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 1 |
| pp242 | Cavia porcellus (domestic guinea pig) | Kd | 3.9000 | 1 | 1 |