oxidopamine has been researched along with Sensitivity and Specificity in 12 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parkinson's disease is characterized by neurodegeneration of the dopaminergic neurons in the substantia nigra pars compacta." | 1.48 | Alterations of the nigrostriatal pathway in a 6-OHDA rat model of Parkinson's disease evaluated with multimodal MRI. ( Butler, B; Felfli, M; Lambert, J; Lehéricy, S; Perlbarg, V; Petiet, A; Privat, AL; Valabrègue, R, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perlbarg, V | 1 |
| Lambert, J | 1 |
| Butler, B | 1 |
| Felfli, M | 1 |
| Valabrègue, R | 1 |
| Privat, AL | 1 |
| Lehéricy, S | 1 |
| Petiet, A | 1 |
| Iravani, B | 1 |
| Towhidkhah, F | 1 |
| Roghani, M | 1 |
| Tang, W | 1 |
| McDowell, K | 1 |
| Limsam, M | 1 |
| Neerchal, NK | 1 |
| Yarowsky, P | 1 |
| Tasch, U | 1 |
| Van Camp, N | 1 |
| Vreys, R | 1 |
| Van Laere, K | 1 |
| Lauwers, E | 1 |
| Beque, D | 1 |
| Verhoye, M | 1 |
| Casteels, C | 1 |
| Verbruggen, A | 1 |
| Debyser, Z | 1 |
| Mortelmans, L | 1 |
| Sijbers, J | 1 |
| Nuyts, J | 1 |
| Baekelandt, V | 1 |
| Van der Linden, A | 1 |
| Rodriguez-Pallares, J | 1 |
| Parga, JA | 1 |
| Joglar, B | 1 |
| Guerra, MJ | 1 |
| Labandeira-Garcia, JL | 1 |
| Coune, PG | 1 |
| Craveiro, M | 1 |
| Gaugler, MN | 1 |
| Mlynárik, V | 1 |
| Schneider, BL | 1 |
| Aebischer, P | 1 |
| Gruetter, R | 1 |
| Yong, WW | 1 |
| Sourial, M | 1 |
| Farmer, PJ | 1 |
| Southwell, BR | 1 |
| Hutson, JM | 1 |
| Kimura, Y | 1 |
| Kihira, K | 1 |
| Miyake, K | 1 |
| Kitaura, T | 1 |
| Fukuchi, H | 1 |
| Poncelet, M | 1 |
| Gueudet, C | 1 |
| Gully, D | 1 |
| Soubrié, P | 1 |
| Le Fur, G | 1 |
| Hossain, MA | 1 |
| Weiner, N | 1 |
| Chen, YC | 1 |
| Galpern, WR | 1 |
| Brownell, AL | 1 |
| Matthews, RT | 1 |
| Bogdanov, M | 1 |
| Isacson, O | 1 |
| Keltner, JR | 1 |
| Beal, MF | 1 |
| Rosen, BR | 1 |
| Jenkins, BG | 1 |
| Ma, KH | 1 |
| Huang, WS | 1 |
| Chen, CH | 1 |
| Lin, SZ | 1 |
| Wey, SP | 1 |
| Ting, G | 1 |
| Wang, SD | 1 |
| Liu, HW | 1 |
| Liu, JC | 1 |
12 other studies available for oxidopamine and Sensitivity and Specificity
| Article | Year |
|---|---|
Alterations of the nigrostriatal pathway in a 6-OHDA rat model of Parkinson's disease evaluated with multimodal MRI.
Topics: Animals; Anisotropy; Case-Control Studies; Corpus Striatum; Disease Models, Animal; Magnetic Resonan | 2018 |
A new feature extraction method and classification of early stage Parkinsonian rats with and without DBS treatment.
Topics: Algorithms; Animals; Artificial Intelligence; Behavior, Animal; Deep Brain Stimulation; Diagnosis, C | 2014 |
Locomotion analysis of Sprague-Dawley rats before and after injecting 6-OHDA.
Topics: Amyotrophic Lateral Sclerosis; Animals; Biomechanical Phenomena; Disease Models, Animal; Locomotion; | 2010 |
Morphologic and functional changes in the unilateral 6-hydroxydopamine lesion rat model for Parkinson's disease discerned with microSPECT and quantitative MRI.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Female; Magnetic Resonance Imaging; Oxidopamine; P | 2010 |
Mitochondrial ATP-sensitive potassium channels enhance angiotensin-induced oxidative damage and dopaminergic neuron degeneration. Relevance for aging-associated susceptibility to Parkinson's disease.
Topics: Aging; Angiotensin II; Animals; Cells, Cultured; Dopaminergic Neurons; Fluorescence; Humans; Immunoh | 2012 |
An in vivo ultrahigh field 14.1 T (1) H-MRS study on 6-OHDA and α-synuclein-based rat models of Parkinson's disease: GABA as an early disease marker.
Topics: alpha-Synuclein; Animals; Biomarkers; Brain; Early Diagnosis; Female; gamma-Aminobutyric Acid; Magne | 2013 |
Does chemical sympathectomy alter the ontogeny of gubernacular migration in vivo?
Topics: Analysis of Variance; Animals; Animals, Newborn; Biopsy, Needle; Cryptorchidism; Disease Models, Ani | 2007 |
Regional characteristics of [125I]cholecystokinin octapeptide specific binding to rat brain membranes following 6-hydroxydopamine treatment.
Topics: Animals; Brain; Cerebral Cortex; Frontal Lobe; Iodine Radioisotopes; Kinetics; Male; Membrane Protei | 1995 |
Turning behavior induced by intrastriatal injection of neurotensin in mice: sensitivity to non-peptide neurotensin antagonists.
Topics: Animals; Behavior, Animal; Brain Diseases; Corpus Striatum; Dopamine; Dose-Response Relationship, Dr | 1994 |
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biopterins; Brain Diseases; Carbidopa; Corpus Striatum; Cyc | 1993 |
Detection of dopaminergic neurotransmitter activity using pharmacologic MRI: correlation with PET, microdialysis, and behavioral data.
Topics: Adrenergic Agents; Animals; Behavior, Animal; Brain; Cocaine; Dextroamphetamine; Dopamine; Dopamine | 1997 |
Dual SPECT of dopamine system using [99mTc]TRODAT-1 and [123I]IBZM in normal and 6-OHDA-lesioned formosan rock monkeys.
Topics: Animals; Benzamides; Brain; Dopamine; Macaca; Organotechnetium Compounds; Oxidopamine; Parkinsonian | 2002 |