melatonin has been researched along with Sensitivity and Specificity in 86 studies
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preclinical evidence suggests that melatonin may affect cellular pathways involved in colorectal cancer (CRC)." | 8.02 | Use of Melatonin Is Associated With Lower Risk of Colorectal Cancer in Older Adults. ( Ji, J; Sundquist, J; Sundquist, K; Zhang, N, 2021) |
| "To investigate the role of NLRP3 inflammasome in muscular aging, we evaluated here the morphological and functional markers of sarcopenia in the NLRP3-knockout mice, as well as the beneficial effect of melatonin supplementation." | 7.91 | Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. ( Acuña-Castroviejo, D; Alsaadawy, RM; Aranda-Martínez, P; Diaz-Casado, ME; Escames, G; Fernández-Martínez, J; Fernández-Ortiz, M; Guerra-Librero, A; López, LC; Sayed, RKA, 2019) |
| "To assess the value of plasma melatonin in predicting acute pancreatitis when combined with the acute physiology and chronic health evaluation II (APACHEII) and bedside index for severity in acute pancreatitis (BISAP) scoring systems." | 7.79 | Clinical significance of melatonin concentrations in predicting the severity of acute pancreatitis. ( Chen, MJ; Dong, LM; Jin, Y; Lin, CJ; Wu, JS; Zhou, Q, 2013) |
| "Based on the potent antioxidant effects of melatonin, we investigated the putative protective role of melatonin against sepsis-induced oxidative organ damage in rats." | 7.73 | Melatonin protects against oxidative organ injury in a rat model of sepsis. ( Ercan, F; Erkanli, G; Kaçmaz, A; Kapucu, C; Sener, G; Tilki, M; Toklu, H; Yeğen, BC, 2005) |
| "Pre-treatment with melatonin (10(-4) M) showed no significant effect on the vasorelaxation by the nitric oxide donor; sodium nitroprusside (10(-7)-10(-5) M)." | 5.35 | Chronic hypoxia inhibits the antihypertensive effect of melatonin on pulmonary artery. ( Ballard, HJ; Balonan, L; Das, R; Ho, S, 2008) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Preclinical evidence suggests that melatonin may affect cellular pathways involved in colorectal cancer (CRC)." | 4.02 | Use of Melatonin Is Associated With Lower Risk of Colorectal Cancer in Older Adults. ( Ji, J; Sundquist, J; Sundquist, K; Zhang, N, 2021) |
| "To investigate the role of NLRP3 inflammasome in muscular aging, we evaluated here the morphological and functional markers of sarcopenia in the NLRP3-knockout mice, as well as the beneficial effect of melatonin supplementation." | 3.91 | Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. ( Acuña-Castroviejo, D; Alsaadawy, RM; Aranda-Martínez, P; Diaz-Casado, ME; Escames, G; Fernández-Martínez, J; Fernández-Ortiz, M; Guerra-Librero, A; López, LC; Sayed, RKA, 2019) |
| "To assess the value of plasma melatonin in predicting acute pancreatitis when combined with the acute physiology and chronic health evaluation II (APACHEII) and bedside index for severity in acute pancreatitis (BISAP) scoring systems." | 3.79 | Clinical significance of melatonin concentrations in predicting the severity of acute pancreatitis. ( Chen, MJ; Dong, LM; Jin, Y; Lin, CJ; Wu, JS; Zhou, Q, 2013) |
| "Aging is known to alter the circadian rhythms of melatonin, serotonin, thermoregulatory responses, cytokine production, and sleep/wakefulness which affect sleep quality." | 3.75 | Melatonin and tryptophan affect the activity-rest rhythm, core and peripheral temperatures, and interleukin levels in the ringdove: changes with age. ( Barriga, C; Bejarano, I; Espino, J; Marchena, AM; Paredes, SD; Reiter, RJ; Rial, RV; Rodríguez, AB, 2009) |
| "Based on the potent antioxidant effects of melatonin, we investigated the putative protective role of melatonin against sepsis-induced oxidative organ damage in rats." | 3.73 | Melatonin protects against oxidative organ injury in a rat model of sepsis. ( Ercan, F; Erkanli, G; Kaçmaz, A; Kapucu, C; Sener, G; Tilki, M; Toklu, H; Yeğen, BC, 2005) |
| "The highly specific antiserum to melatonin (MT) was produced, and the sensitivity and specificity of the radioimmunoassays (RIAs) using this antiserum was investigated." | 3.68 | Radioimmunoassays for melatonin using an antiserum raised against a novel antigen. ( Ji, L; Kanamori, M; Mikami, H; Takatori, T; Terazawa, K; Tomaru, Y, 1992) |
| "Melatonin is an endogenous endolamine hormone that plays an important role in the immune system due to its anti-inflammatory action." | 1.46 | Diagnostic utility of serum melatonin levels in systemic lupus erythematosus: a case-control study. ( Daoud, MS; Gorial, FI; Rasheed, AB, 2017) |
| "Melatonin was detected in 45% of the fully developed purple, postvéraison grapes but only found in 23% of prelag phase samples." | 1.36 | Changes in the levels of indoleamine phytochemicals during véraison and ripening of wine grapes. ( Hall, BA; Le, CH; Murch, SJ; Saxena, PK, 2010) |
| "Pre-treatment with melatonin (10(-4) M) showed no significant effect on the vasorelaxation by the nitric oxide donor; sodium nitroprusside (10(-7)-10(-5) M)." | 1.35 | Chronic hypoxia inhibits the antihypertensive effect of melatonin on pulmonary artery. ( Ballard, HJ; Balonan, L; Das, R; Ho, S, 2008) |
| "Melatonin was determined by enzyme-linked immunosorbent assay (ELISA) in high-performance liquid chromatography (HPLC)-purified extracts." | 1.33 | Quantification of melatonin in phototrophic organisms. ( Lüning, K; Pape, C, 2006) |
| " The role of the NADPH oxidase in promoting oscillations was confirmed by dose-response studies of the effect of diphenylene iodonium, an inhibitor of the NADPH oxidase." | 1.32 | A model of the oscillatory metabolism of activated neutrophils. ( Kindzelskii, AL; Kummer, U; Olsen, LF; Petty, HR, 2003) |
| "Melatonin was extracted from 3 mL plasma using a Waters Oasis HLB solid-phase extraction cartridge and the elute was evaporated to dryness and dissolved in 200 microl mobile phase; acetonitrile-phosphate buffer, 0." | 1.32 | Determination of melatonin in human plasma with solid-phase extraction, high-performance liquid chromatography and fluorescence detection. ( Bergqvist, Y; Römsing, S; Ulfberg, J, 2003) |
| "7-D-Melatonin was added as internal standard and the samples were cleaned and concentrated by solid-phase extraction." | 1.32 | Quantification of melatonin in human saliva by liquid chromatography-tandem mass spectrometry using stable isotope dilution. ( Eriksson, K; Levin, JO; Ostin, A, 2003) |
| "Melatonin has been identified in a number of invertebrates, but little is known of its functions or its circadian control." | 1.32 | A miniature radioimmunoassay for melatonin for use with small samples from invertebrates. ( Gorbet, DJ; Steel, CG, 2003) |
| "Melatonin is an indole hormone produced mainly by the pineal gland." | 1.32 | Melatonin, an endogenous-specific inhibitor of estrogen receptor alpha via calmodulin. ( del Río, B; García Pedrero, JM; Lazo, PS; Martínez-Campa, C; Ramos, S; Zuazua, P, 2004) |
| " The method is, therefore, found to be suitable for melatonin bioavailability studies in rabbits and presumably also in humans." | 1.30 | High-performance liquid chromatographic analysis of melatonin in human plasma and rabbit serum with on-line column enrichment. ( Bechgaard, E; Lindhardt, K; Martinsen, L, 1998) |
| "Melatonin was derivatized under alkaline conditions in the presence of hydrogen peroxide." | 1.30 | Sensitive determination of melatonin by precolumn derivatization and reversed-phase high-performance liquid chromatography. ( Hamase, K; Iinuma, F; Matsubayashi, S; Takahashi, M; Watanabe, M; Zaitsu, K, 1999) |
| "No melatonin was observed in duodenum under conditions of 2." | 1.29 | Duodenum is not a consistent source of melatonin in rats. ( Brammer, GL, 1994) |
| "Melatonin was extracted from an acid homogenate with ethyl acetate to avoid amine interference." | 1.29 | Highly sensitive method for the determination of melatonin by normal-phase high-performance liquid chromatography with fluorometric detection. ( Affanni, JM; Aldana, H; Ferrari, CC; Vitale, AA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 25 (29.07) | 18.2507 |
| 2000's | 42 (48.84) | 29.6817 |
| 2010's | 17 (19.77) | 24.3611 |
| 2020's | 2 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Zhang, N | 1 |
| Sundquist, J | 1 |
| Sundquist, K | 1 |
| Ji, J | 1 |
| Rasheed, AB | 1 |
| Daoud, MS | 1 |
| Gorial, FI | 1 |
| Sayed, RKA | 1 |
| Fernández-Ortiz, M | 1 |
| Diaz-Casado, ME | 1 |
| Aranda-Martínez, P | 1 |
| Fernández-Martínez, J | 1 |
| Guerra-Librero, A | 1 |
| Escames, G | 1 |
| López, LC | 1 |
| Alsaadawy, RM | 1 |
| Acuña-Castroviejo, D | 1 |
| Jin, Y | 1 |
| Lin, CJ | 1 |
| Dong, LM | 1 |
| Chen, MJ | 1 |
| Zhou, Q | 1 |
| Wu, JS | 1 |
| Liebrich, LS | 1 |
| Schredl, M | 1 |
| Findeisen, P | 1 |
| Groden, C | 1 |
| Bumb, JM | 1 |
| Nölte, IS | 1 |
| Al-Ghamdi, M | 1 |
| Al-Ayadhi, L | 1 |
| El-Ansary, A | 1 |
| Sniecinska-Cooper, AM | 1 |
| Shah, AJ | 1 |
| Dimitriou, D | 1 |
| Iles, RK | 1 |
| Butler, SA | 1 |
| Bayford, R | 1 |
| Dirani, M | 1 |
| Nasreddine, W | 1 |
| Melhem, J | 1 |
| Arabi, M | 1 |
| Beydoun, A | 1 |
| Apetrei, IM | 1 |
| Apetrei, C | 1 |
| Soukhtanloo, M | 1 |
| Ansari, M | 1 |
| Paknejad, M | 1 |
| Parizadeh, MR | 1 |
| Rasaee, MJ | 1 |
| Chau, RM | 1 |
| Patel, BA | 1 |
| Paredes, SD | 1 |
| Marchena, AM | 1 |
| Bejarano, I | 1 |
| Espino, J | 1 |
| Barriga, C | 1 |
| Rial, RV | 1 |
| Reiter, RJ | 1 |
| Rodríguez, AB | 1 |
| Shamseer, L | 1 |
| Vohra, S | 1 |
| Muñoz, JL | 1 |
| Ceinos, RM | 1 |
| Soengas, JL | 1 |
| Míguez, JM | 1 |
| Hsing, AW | 1 |
| Meyer, TE | 1 |
| Niwa, S | 1 |
| Quraishi, SM | 1 |
| Chu, LW | 1 |
| Hevia, D | 1 |
| Mayo, JC | 1 |
| Quiros, I | 1 |
| Gomez-Cordoves, C | 1 |
| Sainz, RM | 1 |
| Bagci, S | 1 |
| Mueller, A | 1 |
| Reinsberg, J | 1 |
| Heep, A | 1 |
| Bartmann, P | 1 |
| Franz, AR | 1 |
| Murch, SJ | 3 |
| Hall, BA | 1 |
| Le, CH | 1 |
| Saxena, PK | 2 |
| Stege, PW | 1 |
| Sombra, LL | 1 |
| Messina, G | 1 |
| Martinez, LD | 1 |
| Silva, MF | 1 |
| Langer, SW | 1 |
| Huang, X | 1 |
| Mazza, G | 1 |
| Todoroki, K | 2 |
| Brown, PN | 1 |
| Turi, CE | 1 |
| Shipley, PR | 1 |
| Kasraee, B | 1 |
| Olsen, LF | 1 |
| Kummer, U | 1 |
| Kindzelskii, AL | 1 |
| Petty, HR | 1 |
| Tripp, HM | 1 |
| Warman, GR | 1 |
| Arendt, J | 1 |
| Varma, A | 1 |
| Kaul, RK | 1 |
| Varma, P | 1 |
| Kalra, V | 1 |
| Malhotra, V | 1 |
| Barrett, P | 1 |
| Schuster, C | 1 |
| Mercer, J | 1 |
| Morgan, PJ | 1 |
| Römsing, S | 2 |
| Ulfberg, J | 1 |
| Bergqvist, Y | 2 |
| Eriksson, K | 1 |
| Ostin, A | 1 |
| Levin, JO | 1 |
| Gorbet, DJ | 1 |
| Steel, CG | 1 |
| Nunnari, G | 1 |
| Nigro, L | 1 |
| Palermo, F | 1 |
| Leto, D | 1 |
| Pomerantz, RJ | 1 |
| Cacopardo, B | 1 |
| Motoyama, A | 1 |
| Kanda, T | 1 |
| Namba, R | 1 |
| del Río, B | 1 |
| García Pedrero, JM | 1 |
| Martínez-Campa, C | 1 |
| Zuazua, P | 1 |
| Lazo, PS | 1 |
| Ramos, S | 1 |
| Hamase, K | 2 |
| Hirano, J | 1 |
| Kosai, Y | 1 |
| Tomita, T | 1 |
| Zaitsu, K | 2 |
| Sener, G | 1 |
| Toklu, H | 1 |
| Kapucu, C | 1 |
| Ercan, F | 1 |
| Erkanli, G | 1 |
| Kaçmaz, A | 1 |
| Tilki, M | 1 |
| Yeğen, BC | 1 |
| Cheng, X | 1 |
| van Breemen, RB | 1 |
| Sarkar, M | 1 |
| Prakash, BS | 1 |
| Musijowski, J | 1 |
| Pobozy, E | 1 |
| Trojanowicz, M | 1 |
| Ishimaru, K | 1 |
| Yoshida, H | 1 |
| Yoshitake, T | 1 |
| Nohta, H | 1 |
| Yamaguchi, M | 1 |
| Bökman, F | 1 |
| Pape, C | 1 |
| Lüning, K | 1 |
| Cao, J | 1 |
| O'Brien, R | 1 |
| Wu, X | 1 |
| Wu, W | 1 |
| Zhang, L | 1 |
| Xie, Z | 1 |
| Qiu, B | 1 |
| Chen, G | 1 |
| Yildirim, A | 1 |
| Akkus, M | 1 |
| Nergiz, Y | 1 |
| Baran, OP | 1 |
| Gronfier, C | 1 |
| Wright, KP | 1 |
| Kronauer, RE | 1 |
| Czeisler, CA | 1 |
| Kato, M | 1 |
| Kinoshita, H | 1 |
| Enokita, M | 1 |
| Hori, Y | 1 |
| Hashimoto, T | 1 |
| Iwatsubo, T | 1 |
| Toyo'oka, T | 1 |
| Mahlberg, R | 1 |
| Walther, S | 1 |
| Das, R | 1 |
| Balonan, L | 1 |
| Ballard, HJ | 1 |
| Ho, S | 1 |
| Lipka, E | 1 |
| Danel, C | 1 |
| Orhan, H | 1 |
| Bonte, JP | 2 |
| Vaccher, C | 2 |
| Claustrat, B | 1 |
| Valatx, JL | 1 |
| Harthé, C | 1 |
| Brun, J | 1 |
| Crespi, F | 1 |
| Ratti, E | 1 |
| Trist, DG | 1 |
| Chegini, S | 1 |
| Ehrhart-Hofmann, B | 1 |
| Kaider, A | 1 |
| Waldhauser, F | 1 |
| Mengeaud, V | 1 |
| Skene, D | 1 |
| Pevet, P | 2 |
| Ortonne, JP | 1 |
| Brammer, GL | 1 |
| Pang, CS | 1 |
| Tang, PL | 1 |
| Song, Y | 1 |
| Brown, GM | 2 |
| Pang, SF | 1 |
| Pitrosky, B | 1 |
| Kirsch, R | 1 |
| Vivien-Roels, B | 1 |
| Georg-Bentz, I | 1 |
| Canguilhem, B | 1 |
| Vitale, AA | 1 |
| Ferrari, CC | 1 |
| Aldana, H | 1 |
| Affanni, JM | 1 |
| Peniston-Bird, JF | 1 |
| Di, WL | 1 |
| Street, CA | 1 |
| Edwards, R | 1 |
| Little, JA | 1 |
| Silman, RE | 1 |
| George, A | 1 |
| Poeggeler, B | 1 |
| Huether, G | 1 |
| Klupiec, C | 1 |
| Evans, G | 1 |
| Love, RJ | 1 |
| Kennaway, DJ | 1 |
| Cagnacci, A | 1 |
| Soldani, R | 1 |
| Yen, SS | 1 |
| Yokoyama, T | 2 |
| Shirono, H | 2 |
| Yamada, N | 2 |
| Kato, N | 2 |
| Koga, J | 2 |
| Chanut, E | 1 |
| Nguyen-Legros, J | 1 |
| Versaux-Botteri, C | 1 |
| Trouvin, JH | 1 |
| Launay, JM | 1 |
| Bechgaard, E | 1 |
| Lindhardt, K | 1 |
| Martinsen, L | 1 |
| Iinuma, F | 1 |
| Matsubayashi, S | 1 |
| Takahashi, M | 1 |
| Watanabe, M | 1 |
| Shavali, S | 1 |
| Samejima, M | 1 |
| Uchida, K | 1 |
| Morita, Y | 1 |
| Fukuda, A | 1 |
| Ozeki, Y | 1 |
| Aoki, H | 1 |
| Chae, HD | 1 |
| Park, TJ | 1 |
| Lee, YK | 1 |
| Lee, TG | 1 |
| Kim, KT | 1 |
| Telakivi, T | 1 |
| Rebollar, PG | 1 |
| Ubilla, E | 1 |
| Peleteiro, JB | 1 |
| Agapito, MT | 1 |
| Alvariño, JM | 1 |
| Schumacher, M | 1 |
| Nanninga, A | 1 |
| Werner, R | 1 |
| Olcese, J | 1 |
| Sastre Toraño, J | 1 |
| Rijn-Bikker, Pv | 1 |
| Merkus, P | 1 |
| Guchelaar, HJ | 1 |
| Xue, J | 1 |
| Ying, X | 1 |
| Chen, J | 1 |
| Xian, Y | 1 |
| Jin, L | 1 |
| Caglayan, S | 1 |
| Ozata, M | 1 |
| Ozisik, G | 1 |
| Turan, M | 1 |
| Bolu, E | 1 |
| Oktenli, C | 1 |
| Arslan, N | 1 |
| Erbil, K | 1 |
| Gul, D | 1 |
| Ozdemir, IC | 1 |
| Cornélissen, G | 1 |
| Halberg, F | 1 |
| Burioka, N | 1 |
| Perfetto, F | 1 |
| Tarquini, R | 1 |
| Bakken, EE | 1 |
| Karu, TI | 1 |
| Pyatibrat, LV | 1 |
| Kalendo, GS | 1 |
| Foulon, C | 1 |
| Goossens, JF | 1 |
| Fourmaintraux, E | 1 |
| Rizzo, V | 1 |
| Porta, C | 1 |
| Moroni, M | 1 |
| Scoglio, E | 1 |
| Moratti, R | 1 |
| Rolcík, J | 1 |
| Lenobel, R | 1 |
| Siglerová, V | 1 |
| Strnad, M | 1 |
| Durlach-Misteli, C | 1 |
| Van Ree, JM | 1 |
| Mikami, H | 1 |
| Terazawa, K | 1 |
| Takatori, T | 1 |
| Tomaru, Y | 1 |
| Ji, L | 1 |
| Kanamori, M | 1 |
| Tenn, C | 1 |
| Niles, L | 1 |
| Bar-Or, A | 1 |
| Grossi, D | 1 |
| Kashur, S | 1 |
| Johannson, E | 1 |
| Yie, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identifying the Pathophysiology of Neurogenic Orthostatic Hypotension and the Effects of Melatonin on Reducing Supine Hypertension in Peripherally Intact Versus Denervated Post-ganglionic Sympathetic Nerves[NCT02963181] | Early Phase 1 | 10 participants (Actual) | Interventional | 2018-03-01 | Terminated (stopped due to PI leaving) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for melatonin and Sensitivity and Specificity
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Complementary, holistic, and integrative medicine: melatonin.
Topics: Adolescent; Age Factors; Central Nervous System Depressants; Child; Child, Preschool; Clinical Trial | 2009 |
[Development of novel fluorescence-derivatization-HPLC methods enabling highly sensitive and selective analysis of biological compounds].
Topics: Amines; Amino Acids; Carboxylic Acids; Catalysis; Chromatography, High Pressure Liquid; Electrolysis | 2011 |
Sensitization: a mechanism for melatonin action in the pars tuberalis.
Topics: Adenylyl Cyclases; Animals; Biological Clocks; Cell Line; Cells, Cultured; Circadian Rhythm; Cyclic | 2003 |
Melatonin measurements in tissues. Different recovery of endogenously contained and exogenously added melatonin.
Topics: Animals; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Gas Chromatography | 1996 |
7 trials available for melatonin and Sensitivity and Specificity
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Morphology and function: MR pineal volume and melatonin level in human saliva are correlated.
Topics: Adolescent; Adult; Circadian Rhythm; Female; Humans; Image Interpretation, Computer-Assisted; Imagin | 2014 |
Efficacy of the Sequential Administration of Melatonin, Hydroxyzine, and Chloral Hydrate for Recording Sleep EEGs in Children.
Topics: Central Nervous System Depressants; Child; Child, Preschool; Chloral Hydrate; Conscious Sedation; Dr | 2017 |
Entrainment of the human circadian pacemaker to longer-than-24-h days.
Topics: Adult; Circadian Rhythm; Female; Humans; Male; Melatonin; Sensitivity and Specificity; Time Factors | 2007 |
Actigraphy in agitated patients with dementia. Monitoring treatment outcomes.
Topics: Aged; Aged, 80 and over; Dementia; Dronabinol; Female; Humans; Male; Melatonin; Middle Aged; Monitor | 2007 |
Melatonin enhances cortisol levels in aged women: reversible by estrogens.
Topics: Aging; Double-Blind Method; Estrogens; Female; Humans; Hydrocortisone; Melatonin; Middle Aged; Postm | 1997 |
Do plasma melatonin concentrations decline with age?
Topics: Adult; Aged; Aging; Circadian Rhythm; Confidence Intervals; Female; Humans; Male; Melatonin; Middle | 2000 |
75 other studies available for melatonin and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Use of Melatonin Is Associated With Lower Risk of Colorectal Cancer in Older Adults.
Topics: Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; Humans; Incidence; Male; Melatonin; Middl | 2021 |
Diagnostic utility of serum melatonin levels in systemic lupus erythematosus: a case-control study.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Humans; Immunosuppressive Agents; Lupus Erythematos | 2017 |
Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin.
Topics: Aging; Animals; Biopsy, Needle; Female; Gene Expression Regulation; Immunohistochemistry; Inflammaso | 2019 |
Clinical significance of melatonin concentrations in predicting the severity of acute pancreatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Biomarkers; Case-Control Studies; | 2013 |
Selected biomarkers as predictive tools in testing efficacy of melatonin and coenzyme Q on propionic acid - induced neurotoxicity in rodent model of autism.
Topics: Animals; Autistic Disorder; Biomarkers; Male; Melatonin; Nerve Tissue Proteins; Neuroprotective Agen | 2014 |
Determination of urinary cortisol, cortisone and 6-sulfatoxymelatonin using dilute and shoot ultra-high pressure liquid chromatography-tandem mass spectrometry.
Topics: Child; Child, Preschool; Chromatography, High Pressure Liquid; Cortisone; Female; Humans; Hydrocorti | 2015 |
Voltammetric determination of melatonin using a graphene-based sensor in pharmaceutical products.
Topics: Electrochemical Techniques; Electrodes; Graphite; Limit of Detection; Melatonin; Pharmaceutical Prep | 2016 |
Preparation and characterization of monoclonal antibody against melatonin.
Topics: Animals; Antibodies, Monoclonal; Calibration; Dose-Response Relationship, Drug; Enzyme-Linked Immuno | 2008 |
Determination of serotonin, melatonin and metabolites in gastrointestinal tissue using high-performance liquid chromatography with electrochemical detection.
Topics: Acetonitriles; Animals; Chromatography, High Pressure Liquid; Colon; Drug Stability; Duodenum; Elect | 2009 |
Melatonin and tryptophan affect the activity-rest rhythm, core and peripheral temperatures, and interleukin levels in the ringdove: changes with age.
Topics: Administration, Oral; Aging; Animals; Body Temperature Regulation; Circadian Rhythm; Columbidae; Fem | 2009 |
A simple and sensitive method for determination of melatonin in plasma, bile and intestinal tissues by high performance liquid chromatography with fluorescence detection.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Fluorescence; Intestines; Melatonin; Sensitivit | 2009 |
Measuring serum melatonin in epidemiologic studies.
Topics: Biomarkers, Tumor; Circadian Rhythm; Humans; Male; Melatonin; Neoplasms; Radioimmunoassay; Reproduci | 2010 |
Monitoring intracellular melatonin levels in human prostate normal and cancer cells by HPLC.
Topics: Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Flow Cytometry; Humans; | 2010 |
Utility of salivary melatonin measurements in the assessment of the pineal physiology in newborn infants.
Topics: Enzyme-Linked Immunosorbent Assay; Humans; Infant, Newborn; Linear Models; Melatonin; Pineal Gland; | 2010 |
Changes in the levels of indoleamine phytochemicals during véraison and ripening of wine grapes.
Topics: gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Melatonin; Plant Extracts; Regression | 2010 |
Determination of melatonin in wine and plant extracts by capillary electrochromatography with immobilized carboxylic multi-walled carbon nanotubes as stationary phase.
Topics: Capillary Electrochromatography; Food Analysis; Melatonin; Nanotubes, Carbon; Plant Extracts; Reprod | 2010 |
RE: Kesik et al: melatonin ameliorates doxorubicin-induced skin necrosis in rats.
Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Doxorubicin; Melatonin; Necrosis; Rats; Sensiti | 2010 |
Simultaneous analysis of serotonin, melatonin, piceid and resveratrol in fruits using liquid chromatography tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Citrus sinensis; Fruit; Glucosides; Melatonin; Reproducibility | 2011 |
Comparisons of large (Vaccinium macrocarpon Ait.) and small (Vaccinium oxycoccos L., Vaccinium vitis-idaea L.) cranberry in British Columbia by phytochemical determination, antioxidant potential, and metabolomic profiling with chemometric analysis.
Topics: Anthocyanins; Antioxidants; Ascorbic Acid; British Columbia; Fruit; Glycosylation; Melatonin; Metabo | 2012 |
Peroxidase-mediated mechanisms are involved in the melanocytotoxic and melanogenesis-inhibiting effects of chemical agents.
Topics: Animals; Catechols; Humans; Hydroquinones; Hyperpigmentation; Melanins; Melanocytes; Melatonin; Meth | 2002 |
A model of the oscillatory metabolism of activated neutrophils.
Topics: Catalysis; Cells, Cultured; Coenzymes; Computer Simulation; Horseradish Peroxidase; Humans; Liposome | 2003 |
Circularly polarised MF (500 micro T 50 Hz) does not acutely suppress melatonin secretion from cultured Wistar rat pineal glands.
Topics: Animals; Culture Techniques; Electromagnetic Fields; Flow Cytometry; Male; Melatonin; Pineal Gland; | 2003 |
The effect of antidepressants on serum melatonin levels in endogenous depression.
Topics: Adult; Antidepressive Agents; Biomarkers; Case-Control Studies; Chi-Square Distribution; Depressive | 2002 |
Determination of melatonin in human plasma with solid-phase extraction, high-performance liquid chromatography and fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Fluorometry; Humans; Melatonin; Reproducibility of Results; Se | 2003 |
Quantification of melatonin in human saliva by liquid chromatography-tandem mass spectrometry using stable isotope dilution.
Topics: Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Melatonin; Reproducibility of Resul | 2003 |
A miniature radioimmunoassay for melatonin for use with small samples from invertebrates.
Topics: Animals; Circadian Rhythm; Hemolymph; Melatonin; Radioimmunoassay; Reproducibility of Results; Rhodn | 2003 |
Reduction of serum melatonin levels in HIV-1-infected individuals' parallel disease progression: correlation with serum interleukin-12 levels.
Topics: Analysis of Variance; Biomarkers; Case-Control Studies; CD4 Lymphocyte Count; CD4-CD8 Ratio; Disease | 2003 |
Direct determination of endogenous melatonin in human saliva by column-switching semi-microcolumn liquid chromatography/mass spectrometry with on-line analyte enrichment.
Topics: Adult; Antioxidants; Child, Preschool; Chromatography, High Pressure Liquid; Circadian Rhythm; Femal | 2004 |
Melatonin, an endogenous-specific inhibitor of estrogen receptor alpha via calmodulin.
Topics: Calmodulin; Cell Line, Tumor; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Estrogen Re | 2004 |
A sensitive internal standard method for the determination of melatonin in mammals using precolumn oxidation reversed-phase high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Male; Melatonin; Pineal Gland; Rats; Rats, Wi | 2004 |
Melatonin protects against oxidative organ injury in a rat model of sepsis.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Admini | 2005 |
Mass spectrometry-based screening for inhibitors of beta-amyloid protein aggregation.
Topics: Amyloid beta-Peptides; Chemistry, Pharmaceutical; Daunorubicin; Indoles; Mass Spectrometry; Melatoni | 2005 |
Circadian variations in plasma concentrations of melatonin and prolactin during breeding and non-breeding seasons in yak (Poephagus grunniens L.).
Topics: Animals; Breeding; Cattle; Circadian Rhythm; Female; Immunoenzyme Techniques; Melatonin; Prolactin; | 2005 |
On-line preconcentration techniques in determination of melatonin and its precursors/metabolites using micellar electrokinetic chromatography.
Topics: Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Humans; Melatonin; Re | 2006 |
Simultaneous liquid chromatographic measurement of melatonin and related indoles through post-column electrochemical demethylation and fluorescence derivatization.
Topics: Buffers; Calibration; Chromatography, Liquid; Electrochemistry; Hydrogen-Ion Concentration; Indoles; | 2006 |
Determination of melatonin in saliva using automated solid-phase extraction, high-performance liquid chromatography and fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Humans; Melatonin; Reference Standards; Saliva; Sensitivity an | 2006 |
Quantification of melatonin in phototrophic organisms.
Topics: Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Melatonin; Sensitivity and | 2006 |
Rapid method for accurate analysis of melatonin, serotonin and auxin in plant samples using liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Indoleacetic Acids; Melatonin; Plants; Sensitivity and Specificity; Serotoni | 2006 |
Micellar electrokinetic capillary chromatography for fast separation and sensitive determination of melatonin and related indoleamines using end-column amperometric detection.
Topics: Animals; Buffers; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flo | 2006 |
The effect of melatonin on ductus epididymis. Unilateral testicular torsion in rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Epididymis; Immunohistochemistry; | 2007 |
Analytical method for beta-amyloid fibrils using CE-laser induced fluorescence and its application to screening for inhibitors of beta-amyloid protein aggregation.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Benzothiazoles; Daunorubicin; Fluores | 2007 |
Chronic hypoxia inhibits the antihypertensive effect of melatonin on pulmonary artery.
Topics: Animals; Chronic Disease; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Male; Melatonin; | 2008 |
Chiral resolution of melatoninergic ligands by EKC using highly sulfated CDs.
Topics: beta-Cyclodextrins; Buffers; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Hydro | 2007 |
Effect of constant light on prolactin and corticosterone rhythms evaluated using a noninvasive urine sampling protocol in the rat.
Topics: Animals; Circadian Rhythm; Corticosterone; Light; Male; Melatonin; Photoperiod; Prolactin; Radioimmu | 2008 |
Melatonin, a hormone monitorable in vivo by voltammetry?
Topics: Analysis of Variance; Animals; Brain; Brain Chemistry; Butyrates; Butyric Acid; Electrochemistry; Hy | 1994 |
Direct enzyme-linked immunosorbent assay and a radioimmunoassay for melatonin compared.
Topics: Calibration; Drug Stability; Enzyme-Linked Immunosorbent Assay; Humans; Melatonin; Radioimmunoassay; | 1995 |
No high affinity melatonin binding sites are detected in murine melanoma cells and in normal human melanocytes cultured in vitro.
Topics: Animals; Binding Sites; Chickens; Humans; Iodine Radioisotopes; Kinetics; Melanoma, Experimental; Me | 1994 |
Duodenum is not a consistent source of melatonin in rats.
Topics: 5-Hydroxytryptophan; Animals; Chromatography; Duodenum; In Vitro Techniques; Male; Melatonin; Pineal | 1994 |
2-[125I]Iodomelatonin binding sites in the quail heart: characteristics, distribution and modulation by guanine nucleotides and cations.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Calcium Chloride; Cell Membrane; Chol | 1996 |
The photoperiodic response in Syrian hamster depends upon a melatonin-driven circadian rhythm of sensitivity to melatonin.
Topics: Animals; Circadian Rhythm; Cricetinae; Male; Melatonin; Mesocricetus; Organ Size; Photoperiod; Pinea | 1995 |
Highly sensitive method for the determination of melatonin by normal-phase high-performance liquid chromatography with fluorometric detection.
Topics: Acetates; Animals; Chromatography, High Pressure Liquid; Male; Melatonin; Microchemistry; Pineal Gla | 1996 |
An enzyme immunoassay for 6-sulphatoxy-melatonin in human urine.
Topics: Adolescent; Adult; Child; Cross Reactions; Humans; Immunoenzyme Techniques; Melatonin; Middle Aged; | 1996 |
Clarifying plasma melatonin profiles in domestic pigs: a critical and comparative evaluation of two radioimmunoassay systems.
Topics: Animals; Evaluation Studies as Topic; Fatty Acids, Nonesterified; Female; Melatonin; Pregnancy; Radi | 1997 |
Utilization of changes in the metabolic rate of melatonin receptor-expressing cells to quantify melatonin.
Topics: Animals; Biosensing Techniques; Carbon Dioxide; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Reco | 1998 |
Determination of melatonin in rat pineal, plasma and retina by high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Male; Melatonin; Pineal G | 1998 |
High-performance liquid chromatographic analysis of melatonin in human plasma and rabbit serum with on-line column enrichment.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Melatonin; Rabbits; Sensitivity and Specifici | 1998 |
Sensitive determination of melatonin by precolumn derivatization and reversed-phase high-performance liquid chromatography.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Hydrogen Peroxide; In Vitro Techniques; | 1999 |
Improved enzyme immunoassay method for melatonin: application to the determination of serum melatonin in rats, sheep, and humans.
Topics: Adult; Animals; Female; Humans; Immunoenzyme Techniques; Male; Melatonin; Middle Aged; Rats; Rats, S | 1999 |
A newly developed assay for melatonin using cells expressing human mel-1a receptor.
Topics: Animals; CHO Cells; Cricetinae; DNA, Complementary; Humans; Melatonin; Radioimmunoassay; Radioligand | 1999 |
Rapid and simple measurement of serotonin N-acetyltransferase activity by liquid biphasic diffusion assay.
Topics: Adrenergic beta-Agonists; Animals; Arylamine N-Acetyltransferase; Diffusion; Male; Melatonin; Nerve | 1999 |
[Melatonin and time zone transition].
Topics: Circadian Rhythm; Gastrointestinal Diseases; Humans; Melatonin; Pituitary Gland; Sensitivity and Spe | 1996 |
Determination of plasma melatonin levels by enzyme-linked immunosorbent assay (EIA) in turbot (Scophtalmus maximus L.) and tench (Tinca tinca L.).
Topics: Animals; Cyprinidae; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Flatfishes; Hum | 1999 |
Advanced immunoassays for the direct determination of melatonin in human serum and culture media.
Topics: Cross Reactions; Culture Media; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagent | 1999 |
Quantitative determination of melatonin in human plasma and cerebrospinal fluid with high-performance liquid chromatography and fluorescence detection.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Male; Melatonin; Reference Standards; Reproduci | 2000 |
Amperometric ultramicrosensors for peroxynitrite detection and its application toward single myocardial cells.
Topics: Animals; Animals, Newborn; Calibration; Cells, Cultured; Electrochemistry; Melatonin; Microchemistry | 2000 |
Plasma melatonin concentration before and during testosterone replacement in Klinefelter's syndrome: relation to hepatic indolamine metabolism and sympathoadrenal activity.
Topics: Adrenal Glands; Adult; Catecholamines; Delayed-Action Preparations; Dopamine; Drug Combinations; Epi | 2001 |
Cell attachment modulation by radiation from a pulsed light diode (lambda = 820 nm) and various chemicals.
Topics: Ascorbic Acid; Cell Adhesion; Cells, Cultured; Dinitrophenols; Dose-Response Relationship, Radiation | 2001 |
Chiral capillary electrophoretic determination of the enantiomeric purity of tetrahydronaphthalenic derivatives, melatoninergic ligands, using highly sulfated beta-cyclodextrins.
Topics: beta-Cyclodextrins; Buffers; Cyclodextrins; Electrophoresis, Capillary; Ligands; Melatonin; Reproduc | 2002 |
Determination of free and total (free plus protein-bound) melatonin in plasma and cerebrospinal fluid by high-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Humans; Melatonin; Reproducibility of Results; Sensitivity and | 2002 |
Isolation of melatonin by immunoaffinity chromatography.
Topics: Chromatography, Affinity; Chromatography, High Pressure Liquid; Cross Reactions; Enzyme-Linked Immun | 2002 |
Dopamine and melatonin in the nucleus accumbens may be implicated in the mode of action of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Desipramine; Dopamine; Dose-Response | 1992 |
Radioimmunoassays for melatonin using an antiserum raised against a novel antigen.
Topics: Animals; Antigens; Immune Sera; Melatonin; Rabbits; Radioimmunoassay; Sensitivity and Specificity | 1992 |
A novel and sensitive radioreceptor assay for serum melatonin levels.
Topics: Animals; Chickens; Iodine Radioisotopes; Melatonin; Prosencephalon; Radioligand Assay; Sensitivity a | 1991 |
Urinary 6-sulphatoxymelatonin, an index of pineal function in the rat.
Topics: Animals; Circadian Rhythm; Cross Reactions; Dark Adaptation; Light; Male; Melatonin; Pineal Gland; R | 1991 |