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tetraethylammonium and Sensitivity and Specificity

tetraethylammonium has been researched along with Sensitivity and Specificity in 22 studies

Tetraethylammonium: A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"1 ion channel blocker (TEA) dosage response is characterized and the binding activity is examined."1.33Open-access microfluidic patch-clamp array with raised lateral cell trapping sites. ( Hung, PJ; Lau, AY; Lee, LP; Wu, AR, 2006)
" The dose-response relation for IACh versus ACh concentration was fitted by the Hill equation with EC50 = approx."1.30Nicotinic acetylcholine sensitivity of rat petrosal sensory neurons in dissociated cell culture. ( Nurse, CA; Zhong, H, 1997)
"Choline was a full agonist for alpha 7, but a hydroxyl group was strongly non-permissive for other receptor subtypes (alpha 1 beta 1 gamma delta, alpha 3 beta 4, alpha 3 beta 2, and alpha 4 beta 2)."1.29An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the alpha 7 subtype. ( Bencherif, M; Lippiello, P; Papke, RL, 1996)
" Dose-response relations for TEA and 4-AP were obtained by exposing single cells to ten concentrations exponentially distributed over four orders of magnitude."1.29Variations in the ensemble of potassium currents underlying resonance in turtle hair cells. ( Art, JJ; Goodman, MB, 1996)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (40.91)18.2507
2000's11 (50.00)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, Y1
Kang, Y1
Leung, YM1
Xia, F1
Gao, X1
Xie, H1
Gaisano, HY1
Tsushima, RG1
Oka, T1
Tominaga, Y1
Wakabayashi, Y1
Shoji, A1
Sugawara, M1
Kim, Y1
Rodgers, PJ1
Ishimatsu, R1
Amemiya, S1
Sisk, GD1
Herzog, G1
Glennon, JD1
Arrigan, DW1
Nirmal, J1
Velpandian, T1
Singh, SB1
Biswas, NR1
Thavaraj, V1
Azad, R1
Ghose, S1
Nakayama, S1
Atsuta, S1
Shinmi, T1
Uchiyama, T1
Zhou, ZH1
Unlap, T1
Li, L1
Ma, HP1
Levina, NN1
Dunina-Barkovskaya, AY1
Shabala, S1
Lew, RR1
Purali, N1
Gipson, K1
Bordey, A1
Denton, JS1
Leiter, JC1
Lau, AY1
Hung, PJ1
Wu, AR1
Lee, LP1
Asano, M1
Masuzawa-Ito, K1
Matsuda, T1
Suzuki, Y1
Oyama, H1
Shibuya, M1
Sugita, K1
Buljubasic, N1
Marijic, J1
Kampine, JP1
Bosnjak, ZJ1
Hayashi, T1
Hirono, C1
Young, JA1
Cook, DI1
Park, YB1
Papke, RL1
Bencherif, M1
Lippiello, P1
Goodman, MB1
Art, JJ1
Sabatini, BL1
Regehr, WG1
Zhong, H1
Nurse, CA1
Swart, R1
Koivisto, P1
Markides, KE1
Cox, RH1
Lozinskaya, I1
Dietz, NJ1

Other Studies

22 other studies available for tetraethylammonium and Sensitivity and Specificity

ArticleYear
Modulation of Kv2.1 channel gating and TEA sensitivity by distinct domains of SNAP-25.
    The Biochemical journal, 2006, Jun-01, Volume: 396, Issue:2

    Topics: Allosteric Regulation; Animals; Anti-Dyskinesia Agents; Botulinum Toxins; Botulinum Toxins, Type A;

2006
Comparison of the L-glutamate level in mouse hippocampal slices under tetraethylammonium chloride stimulation as measured with a glass capillary sensor and a patch sensor.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2009, Volume: 25, Issue:3

    Topics: Animals; Ascorbate Oxidase; Biosensing Techniques; Glutamates; Hippocampus; Male; Mice; Patch-Clamp

2009
Subnanomolar ion detection by stripping voltammetry with solid-supported thin polymeric membrane.
    Analytical chemistry, 2009, Sep-01, Volume: 81, Issue:17

    Topics: Arsenates; Electrochemistry; Ion-Selective Electrodes; Membranes, Artificial; Quaternary Ammonium Co

2009
Assessment of ion transfer amperometry at liquid-liquid interfaces for detection in CE.
    Electrophoresis, 2009, Volume: 30, Issue:19

    Topics: Benzenesulfonates; Electrochemistry; Electrolytes; Electrophoresis, Capillary; Equipment Design; Ion

2009
Development and validation of a highly sensitive LC-MS/MS method for organic cation transporter (OCT) substrate tetraethylammonium (TEA) in rabbits.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Mar-15, Volume: 879, Issue:9-10

    Topics: Animals; Chromatography, Liquid; Drug Stability; Linear Models; Models, Biological; Models, Chemical

2011
Pulse-driven magnetoimpedance sensor detection of biomagnetic fields in musculatures with spontaneous electric activity.
    Biosensors & bioelectronics, 2011, Sep-15, Volume: 27, Issue:1

    Topics: Animals; Electric Impedance; Electromagnetic Fields; Electrophysiological Phenomena; Guinea Pigs; Mu

2011
Incomplete inactivation of voltage-dependent K+ channels in human B lymphoma cells.
    The Journal of membrane biology, 2002, Jul-15, Volume: 188, Issue:2

    Topics: Electric Conductivity; Electrophysiology; Humans; Lymphoma, B-Cell; Membrane Potentials; Oligonucleo

2002
Blue light modulation of ion transport in the slime mutant of Neurospora crassa.
    The Journal of membrane biology, 2002, Aug-01, Volume: 188, Issue:3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Barium Compounds; Cell Line; Chlorides; Electric C

2002
Firing properties of the soma and axon of the abdominal stretch receptor neurons in the crayfish (Astacus leptodactylus).
    General physiology and biophysics, 2002, Volume: 21, Issue:2

    Topics: Abdomen; Action Potentials; Adaptation, Physiological; Animals; Astacoidea; Axons; Electric Stimulat

2002
Analysis of the K+ current profile of mature rat oligodendrocytes in situ.
    The Journal of membrane biology, 2002, Oct-01, Volume: 189, Issue:3

    Topics: Animals; Barium; Cesium; Corpus Callosum; Electric Conductivity; In Vitro Techniques; Ion Transport;

2002
Anomalous effects of external TEA on permeation and gating of the A-type potassium current in H. aspersa neuronal somata.
    The Journal of membrane biology, 2002, Nov-01, Volume: 190, Issue:1

    Topics: Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; Helix, Snails; Incidental Fin

2002
Open-access microfluidic patch-clamp array with raised lateral cell trapping sites.
    Lab on a chip, 2006, Volume: 6, Issue:12

    Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Dimethylpolysiloxanes; Dose-Response Relationship,

2006
Functional role of charybdotoxin-sensitive K+ channels in the resting state of cerebral, coronary and mesenteric arteries of the dog.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Calcium-sensitive potassium current in isolated canine coronary smooth muscle cells.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:3

    Topics: Animals; Apamin; Calcimycin; Calcium; Charybdotoxin; Coronary Vessels; Dogs; Electric Conductivity;

1994
The ACh-induced whole-cell currents in sheep parotid secretory cells. Do BK channels really carry the ACh-evoked whole-cell K+ current?
    The Journal of membrane biology, 1995, Volume: 144, Issue:2

    Topics: 4-Aminopyridine; Acetylcholine; Animals; Barium; Cell Membrane; Chlorides; Parotid Gland; Patch-Clam

1995
Ion selectivity and gating of small conductance Ca(2+)-activated K+ channels in cultured rat adrenal chromaffin cells.
    The Journal of physiology, 1994, Dec-15, Volume: 481 ( Pt 3)

    Topics: Adrenal Medulla; Animals; Apamin; Calcium; Electric Conductivity; Electrophysiology; Ion Channel Gat

1994
An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the alpha 7 subtype.
    Neuroscience letters, 1996, Aug-09, Volume: 213, Issue:3

    Topics: Acetylcholine; Animals; Choline; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Fema

1996
Variations in the ensemble of potassium currents underlying resonance in turtle hair cells.
    The Journal of physiology, 1996, Dec-01, Volume: 497 ( Pt 2)

    Topics: 4-Aminopyridine; Animals; Dose-Response Relationship, Drug; Electric Impedance; Electrophysiology; H

1996
Control of neurotransmitter release by presynaptic waveform at the granule cell to Purkinje cell synapse.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, May-15, Volume: 17, Issue:10

    Topics: Action Potentials; Animals; Calcium; Calcium Channels; Fluorescent Dyes; Glutamic Acid; Ion Channel

1997
Nicotinic acetylcholine sensitivity of rat petrosal sensory neurons in dissociated cell culture.
    Brain research, 1997, Aug-22, Volume: 766, Issue:1-2

    Topics: Acetylcholine; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Electric Conductivity; He

1997
Capillary solid-phase extraction-tandem mass spectrometry for fast quantification of free concentrations of tolterodine and two metabolites in ultrafiltered plasma samples.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Dec-24, Volume: 736, Issue:1-2

    Topics: Benzhydryl Compounds; Chromatography, High Pressure Liquid; Cresols; Ethylamines; Mass Spectrometry;

1999
Differences in K+ current components in mesenteric artery myocytes from WKY and SHR.
    American journal of hypertension, 2001, Volume: 14, Issue:9 Pt 1

    Topics: Animals; Calcium Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; M

2001