Compounds > 4-vinylpyridine
Page last updated: 2024-09-21

4-vinylpyridine

Description

4-vinylpyridine: reagent for blocking cysteine function in proteins; RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID7502
CHEMBL ID4550330
SCHEMBL ID14867
SCHEMBL ID12284753
MeSH IDM0093637

Synonyms (53)

Synonym
V0150
ccris 5240
nsc 18256
hsdb 1509
4-ethenylpyridine
einecs 202-852-0
4vp ,
gamma-vinylpyridine
100-43-6
pyridine, 4-vinyl-
4-vinylpyridine
pyridine, 4-ethenyl-
nsc18256
nsc-18256
inchi=1/c7h7n/c1-2-7-3-5-8-6-4-7/h2-6h,1h
4-vinylpyridine, contains 100 ppm hydroquinone as inhibitor, 95%
V0025
25232-41-1
STK802321
AKOS000119179
unii-i56g67xm8d
ec 202-852-0
i56g67xm8d ,
FT-0619555
FT-0619556
4-vinylpyridine [hsdb]
2-(4-pyridyl)ethylene
.gamma.-vinylpyridine
BBL027584
SCHEMBL14867
4-vinyl-pyridine
4-pyridylethylene
4-(1-ethenyl)pyridine
4-vinyl pyridine
dtxcid4030047
NCGC00357114-01
tox21_303844
dtxsid0051499 ,
cas-100-43-6
SCHEMBL12284753
mfcd00006447
J-000133
J-516030
F0001-0017
pyridine,4-ethenyl-
95343-78-5
VS-08564
4-vinylpyridine (stabilized with hq)
Q13427555
ethyl1-propenylether
CHEMBL4550330
EN300-21304
pesticide code: 128899

Pathways (1)

4-vinylpyridine is involved in 1 pathway(s), involving a total of 4 unique proteins and 42 unique compounds

PathwayProteinsCompounds
sinapate ester biosynthesis221

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency2.73060.001530.607315,848.9004AID1224841
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1637722Glutathione reactivity assessed as half life at 250 uM up to 72 hrs by HPLC-MS or NMR analysis2019MedChemComm, Feb-01, Volume: 10, Issue:2
Design and characterization of a heterocyclic electrophilic fragment library for the discovery of cysteine-targeted covalent inhibitors.
AID1637721Glutathione reactivity assessed as thiol reactivity rate constant at 250 uM up to 72 hrs by HPLC-MS or NMR analysis2019MedChemComm, Feb-01, Volume: 10, Issue:2
Design and characterization of a heterocyclic electrophilic fragment library for the discovery of cysteine-targeted covalent inhibitors.
AID1637723Stability of the compound assessed as half life for degradation2019MedChemComm, Feb-01, Volume: 10, Issue:2
Design and characterization of a heterocyclic electrophilic fragment library for the discovery of cysteine-targeted covalent inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (155)

TimeframeStudies, This Drug (%)All Drugs %
pre-199013 (8.39)18.7374
1990's31 (20.00)18.2507
2000's45 (29.03)29.6817
2010's63 (40.65)24.3611
2020's3 (1.94)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (1.27%)6.00%
Case Studies3 (1.90%)4.05%
Observational0 (0.00%)0.25%
Other153 (96.84%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
3-cyanopyridine[no description available]medium10nitrile;
pyridines
4-cyanopyridine[no description available]medium10
2-vinylpyridine[no description available]medium90
2-chloropyridine[no description available]medium10monochloropyridine
cyanopyrazine[no description available]medium10nitrile;
pyrazines
ethylene dimethacrylate[no description available]medium230enoate esterallergen;
cross-linking reagent;
polymerisation monomer
zearalenone[no description available]medium20macrolide;
resorcinols		fungal metabolite;
mycoestrogen
quercetin[no description available]medium207-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
terephthalic acid[no description available]medium10benzenedicarboxylic acid
bromates[no description available]medium10bromine oxoanion;
monovalent inorganic anion
zinc oxide[no description available]medium10zinc molecular entity
intybin[no description available]medium10
sesquiterpenes[no description available]medium10
n,n'-methylenebisacrylamide[no description available]medium10
n-isopropylacrylamide[no description available]medium20
cellulose[no description available]medium70glycoside
hydrogen[no description available]medium20elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
paclitaxel[no description available]medium10taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
naproxen[no description available]medium30methoxynaphthalene;
monocarboxylic acid		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
4-chlorostyrene[no description available]medium10
acrylonitrile[no description available]medium20aliphatic nitrile;
volatile organic compound		antifungal agent;
carcinogenic agent;
fungal metabolite;
mutagen;
polar aprotic solvent
nitroxyl[no description available]medium10nitrogen oxoacid
iodoacetamide[no description available]medium70
acrylamide[no description available]medium80acrylamides;
N-acylammonia;
primary carboxamide		alkylating agent;
carcinogenic agent;
Maillard reaction product;
mutagen;
neurotoxin
ethylmaleimide[no description available]medium70maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
bisphenol a[no description available]medium40bisphenolendocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen
salicylic acid[no description available]medium20monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
trimethylolpropane trimethacrylate[no description available]medium10carbonyl compound
chloramphenicol[no description available]medium10C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
chlorogenic acid[no description available]medium10cinnamate ester;
tannin		food component;
plant metabolite
1-butyl-3-methylimidazolium tetrafluoroborate[no description available]medium20
selenium[no description available]medium20chalcogen;
nonmetal atom		micronutrient
itaconic acid[no description available]medium10dicarboxylic acid;
dicarboxylic fatty acid;
olefinic compound		fungal metabolite;
human metabolite
pindolol[no description available]medium10indoles;
secondary amine		antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent
glyburide[no description available]medium10monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent
carprofen[no description available]medium10carbazoles;
organochlorine compound		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug;
photosensitizing agent
aspirin[no description available]medium30benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
silver[no description available]medium10copper group element atom;
elemental silver		Escherichia coli metabolite
1,2-dipalmitoylphosphatidylglycerol[no description available]medium10phosphatidylglycerol
1,2-dipalmitoylphosphatidylcholine[no description available]medium10
azobis(isobutyronitrile)[no description available]medium30
divinyl benzene[no description available]medium50styrenes
toluene[no description available]medium30methylbenzene;
toluenes;
volatile organic compound		cholinergic antagonist;
fuel additive;
neurotoxin;
non-polar solvent
clay[no description available]medium10
methacrylic acid[no description available]medium90alpha,beta-unsaturated monocarboxylic acid
acetonitrile[no description available]medium30aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
daidzein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
phytoestrogen;
plant metabolite
genistein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
biochanin a[no description available]medium104'-methoxyisoflavones;
7-hydroxyisoflavones		antineoplastic agent;
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
chicoric acid[no description available]medium10organooxygen compoundgeroprotector;
HIV-1 integrase inhibitor
cysteine[no description available]medium260cysteiniumfundamental metabolite
hydroxyethyl methacrylate[no description available]medium50enoate esterallergen;
polymerisation monomer
limestone[no description available]medium10calcium salt;
carbonate salt;
inorganic calcium salt;
one-carbon compound		antacid;
fertilizer;
food colouring;
food firming agent
hydrochloric acid[no description available]medium10chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride		mouse metabolite
methacrylamide[no description available]medium20acrylamides;
primary carboxamide
betadex[no description available]medium20cyclodextrin
iodoacetic acid[no description available]medium50haloacetic acid;
organoiodine compound		alkylating agent
peroxyformic acid[no description available]medium40
dithiothreitol[no description available]medium701,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
asparagine[no description available]medium10amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
acrylic acid[no description available]medium40alpha,beta-unsaturated monocarboxylic acidmetabolite
cadmium[no description available]medium10cadmium molecular entity;
zinc group element atom
chromium[no description available]medium20chromium group element atom;
metal allergen		micronutrient
4-nonylphenol[no description available]medium10phenolsenvironmental contaminant
atrazine[no description available]medium10chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
styrene[no description available]medium70styrenes;
vinylarene;
volatile organic compound		mouse metabolite;
mutagen;
plant metabolite
methyl acrylate[no description available]medium20enoate ester
hydroxyethylcellulose[no description available]medium10
fenoprop[no description available]medium10monocarboxylic acidphenoxy herbicide
2,4-dichlorophenoxyacetic acid[no description available]medium40chlorophenoxyacetic acid;
dichlorobenzene		agrochemical;
defoliant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
environmental contaminant;
phenoxy herbicide;
synthetic auxin
2,4,5-trichlorophenoxyacetic acid[no description available]medium10chlorophenoxyacetic acid;
trichlorobenzene		defoliant;
phenoxy herbicide;
synthetic auxin
4-nitrophenol[no description available]medium204-nitrophenolshuman xenobiotic metabolite;
mouse metabolite
nitrophenols[no description available]medium30
methanol[no description available]medium30alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
formic acid[no description available]medium10monocarboxylic acidantibacterial agent;
astringent;
metabolite;
protic solvent;
solvent
2-naphthol[no description available]medium10naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
titanium[no description available]medium10titanium group element atom
titanium dioxide[no description available]medium10titanium oxidesfood colouring
trichlorosilane[no description available]medium10
1-hexylpyridinium[no description available]medium10
butyl bromide[no description available]medium20
3-hydroxyflavone[no description available]medium10flavonols;
monohydroxyflavone
chloroform[no description available]medium10chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
chromium[no description available]medium10chromium cation;
monoatomic hexacation
indoleacetic acid[no description available]medium10indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite
eicosane[no description available]medium10long-chain alkaneplant metabolite
mercury[no description available]medium10elemental mercury;
zinc group element atom		neurotoxin
resveratrol[no description available]medium10resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
stilbenes[no description available]medium20stilbene
solanesol[no description available]medium10nonaprenol;
primary alcohol		plant metabolite
cotinine[no description available]medium10N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid		antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite
nicotine[no description available]medium103-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
formaldehyde[no description available]medium10aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
acetaldehyde[no description available]medium10aldehydecarcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent
4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol[no description available]medium10nitrosamine;
pyridines;
secondary alcohol		biomarker;
carcinogenic agent;
human urinary metabolite
flufenamic acid[no description available]medium10aromatic amino acid;
organofluorine compound		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
allylamine[no description available]medium10alkylamine
veratric acid[no description available]medium10benzoic acidsallergen;
plant metabolite
allylthiourea[no description available]medium10thioureasmetabolite
thiourea[no description available]medium10one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
2-propenylurea[no description available]medium10
piperazine[no description available]medium10azacycloalkane;
piperazines;
saturated organic heteromonocyclic parent		anthelminthic drug
vanillic acid[no description available]medium10methoxybenzoic acid;
monohydroxybenzoic acid		plant metabolite
urea[no description available]medium10isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
3-nitrotyrosine[no description available]medium102-nitrophenols;
C-nitro compound;
nitrotyrosine;
non-proteinogenic alpha-amino acid
tyrosine[no description available]medium10amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
4-nitro-3-cresol[no description available]medium104-nitrophenols
nitrobenzene[no description available]medium10nitroarene;
nitrobenzenes
thorium[no description available]medium10actinoid atom;
f-block element atom
fluorouracil[no description available]medium10nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
caffeic acid[no description available]medium10caffeic acidgeroprotector;
mouse metabolite
propyl gallate[no description available]medium10trihydroxybenzoic acid
protocatechuic acid[no description available]medium10catechols;
dihydroxybenzoic acid		antineoplastic agent;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
human xenobiotic metabolite;
plant metabolite
arachidonic acid[no description available]medium10icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
1,7-phenanthroline[no description available]medium10phenanthroline
amiodarone[no description available]medium101-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
ferric chloride[no description available]medium10iron coordination entityastringent;
Lewis acid
benzene[no description available]medium20aromatic annulene;
benzenes;
volatile organic compound		carcinogenic agent;
environmental contaminant;
non-polar solvent
chlorine[no description available]medium10halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
arsenic[no description available]medium20metalloid atom;
pnictogen		micronutrient
propazine[no description available]medium10chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
organophosphonates[no description available]medium10divalent inorganic anion;
phosphite ion
sorbic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acid;
sorbic acid
muconic acid[no description available]medium10muconic acidbiomarker;
human xenobiotic metabolite
diethyl phthalate[no description available]medium10diester;
ethyl ester;
phthalate ester		neurotoxin;
plasticiser;
teratogenic agent
oleanolic acid[no description available]medium10hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
methane[no description available]medium10alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound		bacterial metabolite;
fossil fuel;
greenhouse gas
ibuprofen[no description available]medium20monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic
pyridine[no description available]medium10azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines		environmental contaminant;
NMR chemical shift reference compound
copper gluconate[no description available]medium10organic molecular entity
gluconic acid[no description available]medium10gluconic acidchelator;
Penicillium metabolite
4-chloro-7-nitrobenzofurazan[no description available]medium10benzoxadiazole;
C-nitro compound;
organochlorine compound		EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.6.1.3 (adenosinetriphosphatase) inhibitor;
fluorescent probe;
fluorochrome
7-fluoro-4-nitrobenzo-2-oxa-1,3-diazole[no description available]medium10
nilvadipine[no description available]medium10dihydropyridine;
isopropyl ester;
methyl ester;
nitrile
nifedipine[no description available]medium10C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
salicylaldoxime[no description available]medium10
uranium[no description available]medium10actinoid atom;
f-block element atom;
monoatomic uranium
methyl cellosolve[no description available]medium10glycol etherprotic solvent;
solvent
3-(trimethoxysilyl)propyl methacrylate[no description available]medium10
gold[no description available]medium10copper group element atom;
elemental gold
platinum[no description available]medium10elemental platinum;
nickel group element atom;
platinum group metal atom
dimethyl sulfoxide[no description available]medium10sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
ruthenium chloride (rucl3)[no description available]medium10
acenaphthene[no description available]medium10acenaphthenes
2,5-dimethylfuran[no description available]medium10furansantifungal agent;
bacterial metabolite;
fuel;
fumigant;
human urinary metabolite;
Maillard reaction product;
plant metabolite
phenyl acetate[no description available]medium20benzenes;
phenyl acetates
2-methyl-4-chlorophenoxyacetic acid[no description available]medium10chlorophenoxyacetic acid;
monochlorobenzenes		environmental contaminant;
phenoxy herbicide;
synthetic auxin
phenoxyacetic acid[no description available]medium10aromatic ether;
monocarboxylic acid		allergen;
Aspergillus metabolite;
human xenobiotic metabolite;
plant growth retardant
benzoic acid[no description available]medium10benzoic acidsalgal metabolite;
antimicrobial food preservative;
drug allergen;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
human xenobiotic metabolite;
plant metabolite
cobalt[no description available]medium20cobalt group element atom;
metal allergen		micronutrient
cupric chloride[no description available]medium10copper molecular entity;
inorganic chloride		EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor
hydroxyethyl methacrylate-ethyl methacrylate[no description available]medium10
ciprofloxacin[no description available]medium10aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
methylene chloride[no description available]medium10chloromethanes;
volatile organic compound		carcinogenic agent;
polar aprotic solvent;
refrigerant
n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine[no description available]medium10N-substituted diamine;
pyridines;
tertiary amino compound		apoptosis inducer;
chelator;
copper chelator
2,3,4,6-tetrachlorophenol[no description available]medium10tetrachlorophenolxenobiotic metabolite
2,4-dichlorophenol[no description available]medium10dichlorophenol
trifluoroacetic acid[no description available]medium10fluoroalkanoic acidhuman xenobiotic metabolite;
NMR chemical shift reference compound;
reagent
3-bromopropylamine[no description available]medium10
gamma-glutamylcysteine[no description available]medium10gamma-glutamylcysteineEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
streptomycin[no description available]medium10antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor
tryptophan[no description available]medium20erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
methionine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
dithionitrobenzoic acid[no description available]medium20nitrobenzoic acid;
organic disulfide		indicator
guanidine[no description available]medium20carboxamidine;
guanidines;
one-carbon compound
succinic acid[no description available]medium10alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
lewisite[no description available]medium10
succinic anhydride[no description available]medium10cyclic dicarboxylic anhydride;
tetrahydrofurandione
lysine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
selenocysteine[no description available]medium20
nadp[no description available]medium10
dinitrochlorobenzene[no description available]medium20C-nitro compound;
monochlorobenzenes		allergen;
epitope;
sensitiser
aspartic acid[no description available]medium10aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
divercin v41[no description available]medium10
aziridine[no description available]medium10azacycloalkane;
aziridines;
saturated organic heteromonocyclic parent		alkylating agent
tris(2-carboxyethyl)phosphine[no description available]medium20phosphine derivative;
tricarboxylic acid		reducing agent
cyanogen bromide[no description available]medium20
cystine[no description available]medium20
alanine[no description available]medium10alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide[no description available]medium10epoxideintercalator
3-vinylpyridine[no description available]medium20
4-acetamido-4'-maleimidylstilbene-2,2'-disulfonic acid[no description available]medium10
11-cis-retinal[no description available]medium10retinalchromophore;
human metabolite;
mouse metabolite
guanylyl imidodiphosphate[no description available]medium10nucleoside triphosphate analogue
2-nitro-5-thiocyanobenzoic acid[no description available]medium10
ethylene glycol[no description available]medium10ethanediol;
glycol		metabolite;
mouse metabolite;
solvent;
toxin
argon[no description available]medium10monoatomic argon;
noble gas atom;
p-block element atom		food packaging gas;
neuroprotective agent
carbon monoxide[no description available]medium10carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
dipicolinic acid[no description available]medium10pyridinedicarboxylic acidbacterial metabolite
4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone[no description available]medium10nitrosamine;
pyridines
dinoprostone[no description available]medium10prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
indomethacin[no description available]medium10aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
benzoxazoles[no description available]medium101,3-benzoxazoles;
mancude organic heterobicyclic parent
muramidase[no description available]medium20
ninhydrin[no description available]medium10aromatic ketone;
beta-diketone;
indanones;
ketone hydrate		colour indicator;
human metabolite
acetic acid[no description available]medium10monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
aminopenicillanic acid[no description available]medium10amino acid zwitterion;
penicillanic acids		allergen
penicillanic acid[no description available]medium10penicillanic acids
serine[no description available]medium10L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
phenylmethylsulfonyl fluoride[no description available]medium10acyl fluorideserine proteinase inhibitor
phenylisothiocyanate[no description available]medium10isothiocyanateallergen;
reagent
p-dimethylaminoazobenzene[no description available]medium10azobenzenes
4-dimethylaminoazobenzene-4'-iodoacetamide[no description available]medium10
sodium bromide[no description available]medium10bromide salt;
inorganic sodium salt
oligomycins[no description available]medium10
bromide[no description available]medium10halide anion;
monoatomic bromine
tri-n-butylphosphine[no description available]medium10
ConditionIndicatedRelationship StrengthStudiesTrials
Allergic Contact Dermatitis0low10
Anasarca0low10
Arsenic Encephalopathy0low10
Arsenic Induced Polyneuropathy0low10
Arsenic Poisoning0low10
Arsenic Poisoning, Inorganic0low10
Arsenic Poisoning, Nervous System0low10
Arsenic Poisoning, Organic0low10
Bleb0low10
Blister0low10
Bulla0low10
Bullae0low10
Bullous Lesion0low10
Burns, Chemical0low10
Cancer of Lung0low10
Cancer of the Lung0low10
Caries, Dental0low10
Carious Dentin0low10
Carious Lesions0low10
Central Nervous System Origin Vertigo0low10
Chemical Burns0low10
CNS Origin Vertigo0low10
Contact Dermatitis0low10
Decay, Dental0low10
Dental Caries0low10
Dental Decay0low10
Dental White Spot0low10
Dental White Spots0low10
Dermatitis Venenata0low10
Dermatitis, Allergic Contact0low10
Dermatitis, Allergic Eczematous0low10
Dermatitis, Contact0low10
Dermatitis, Contact, Allergic0low10
Dermatitis, Occupational0low20
Dermatosis, Industrial0low20
Diabetes Mellitus, Adult-Onset0low10
Diabetes Mellitus, Ketosis-Resistant0low10
Diabetes Mellitus, Maturity-Onset0low10
Diabetes Mellitus, Non Insulin Dependent0low10
Diabetes Mellitus, Non-Insulin-Dependent0low10
Diabetes Mellitus, Noninsulin Dependent0low10
Diabetes Mellitus, Noninsulin-Dependent0low10
Diabetes Mellitus, Slow-Onset0low10
Diabetes Mellitus, Stable0low10
Diabetes Mellitus, Type 20low10
Diabetes Mellitus, Type II0low10
Dizziness0low10
Dizzyness0low10
Dropsy0low10
Eczema, Contact0low10
Edema0low10
Electrolytes0low20
Encephalopathy, Arsenic0low10
Extravascular Hemolysis0low10
Foot Ulcer0low10
Forearm Injuries0low10
Gambling0low10
Gambling, Pathologic0low10
Gambling, Pathological0low10
Gastric Ulcer0low10
Genetic Predisposition0low10
Genetic Predisposition to Disease0low10
Genetic Susceptibility0low10
Haemolysis0low10
Hand Dermatoses0low10
Hand Dermatosis0low10
Hemolysis0low10
Hives0low10
Hydrops0low10
Hypersensitivity, Contact0low10
Industrial Dermatosis0low20
Injuries, Forearm0low10
Injuries, Leg0low10
Inorganic Arsenic Poisoning0low10
Intravascular Hemolysis0low10
Leg Injuries0low10
Light-Headedness0low10
Lightheadedness0low10
Lung Cancer0low10
Lung Neoplasms0low10
Maturity-Onset Diabetes0low10
Maturity-Onset Diabetes Mellitus0low10
MODY0low10
Neoplasms, Lung0low10
Neoplasms, Pulmonary0low10
Nervous System Poisoning, Arsenic0low10
Nervous System, Organic Arsenic Poisoning0low10
Neurotoxicity Syndrome, Arsenical0low10
NIDDM0low10
Noninsulin-Dependent Diabetes Mellitus0low10
Occupational Dermatitis0low20
Organic Arsenic Poisoning, Nervous System0low10
Orthostasis0low10
Pathological Gambling0low10
Plantar Ulcer0low10
Poisoning, Arsenic, Nervous System0low10
Polyneuropathy, Arsenic-Induced0low10
Positional Vertigo0low10
Predisposition, Genetic0low10
Pulmonary Cancer0low10
Pulmonary Neoplasms0low10
Recrudescence0low10
Recurrence0low10
Relapse0low10
Sensitivity and Specificity0low70
Sensitivity, Contact0low10
Spinning Sensation0low10
Stomach Ulcer0low10
Susceptibility, Genetic0low10
Type 2 Diabetes0low10
Type 2 Diabetes Mellitus0low10
Urticaria0low10
Vertigo0low10
Vertigo, Brain Stem0low10
Vertigo, Brainstem0low10
Vertigo, Central Nervous System Origin0low10
Vertigo, Central Origin0low10
Vertigo, Constant0low10
Vertigo, Essential0low10
Vertigo, Intermittant0low10
Vertigo, Paroxysmal0low10
Vertigo, Peripheral0low10
Vertigo, Subjective0low10
Vesication0low10
White Spot, Dental0low10
White Spots, Dental0low10

Research Highlights

Safety/Toxicity (2)

ArticleYear
Correlation of [RuCl3(dppb)(VPy)] cytotoxicity with its effects on the cell membranes: an investigation using Langmuir monolayers as membrane models.
The journal of physical chemistry. B, Sep-11, Volume: 118, Issue: 36		2014
A study of tobacco carcinogenesis. XLVII. Bioassays of vinylpyridines for genotoxicity and for tumorigenicity in A/J mice.
Cancer letters, Aug-14, Volume: 65, Issue: 2		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Use of peak sharpening effects to improve the separation of chiral compounds with molecularly imprinted porous polymer layer open-tubular capillaries.
Electrophoresis, Volume: 38, Issue: 8		2017
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (1)

ArticleYear
Aromatic organic contaminant removal from an aqueous environment by p(4-VP)-based materials.
Chemosphere, Volume: 85, Issue: 5		2011
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (1)

ArticleYear
Synthesis and adsorption performance of lead ion-imprinted micro-beads with combination of two functional monomers.
Journal of environmental sciences (China), Volume: 23, Issue: 12		2011
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]