Page last updated: 2024-08-07 17:21:50
Acyl-CoA:cholesterol acyltransferase
[no definition available]
Synonyms
Research
Bioassay Publications (13)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (69.23) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (18)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| tacrine | Oryctolagus cuniculus (rabbit) | IC50 | 0.2670 | 1 | 1 |
| donepezil | Oryctolagus cuniculus (rabbit) | IC50 | 0.0080 | 1 | 1 |
| physostigmine | Oryctolagus cuniculus (rabbit) | IC50 | 0.0189 | 1 | 1 |
| 3,5-dichlorosalicylic acid | Oryctolagus cuniculus (rabbit) | Ki | 24.0000 | 1 | 1 |
| lovastatin | Oryctolagus cuniculus (rabbit) | IC50 | 16.8000 | 1 | 1 |
| zileuton | Oryctolagus cuniculus (rabbit) | IC50 | 55.0000 | 1 | 1 |
| pd 128042 | Oryctolagus cuniculus (rabbit) | IC50 | 0.1488 | 3 | 4 |
| ramatroban | Oryctolagus cuniculus (rabbit) | IC50 | 7.6555 | 2 | 2 |
| cl 277082 | Oryctolagus cuniculus (rabbit) | IC50 | 0.1433 | 3 | 4 |
| n-(2,6-bis(1-methylethyl)phenyl)-n'-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea hydrochloride | Oryctolagus cuniculus (rabbit) | IC50 | 0.0520 | 1 | 1 |
| n-(2,6-bis(isopropyl)phenyl)-n'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea | Oryctolagus cuniculus (rabbit) | IC50 | 0.0370 | 1 | 1 |
| e 5324 | Oryctolagus cuniculus (rabbit) | IC50 | 0.0880 | 1 | 1 |
| avasimibe | Oryctolagus cuniculus (rabbit) | IC50 | 7.6000 | 1 | 1 |
| pactimibe | Oryctolagus cuniculus (rabbit) | IC50 | 6.3333 | 3 | 3 |
| oleoylanilide | Oryctolagus cuniculus (rabbit) | IC50 | 26.0000 | 1 | 1 |
| pd 138142-15 | Oryctolagus cuniculus (rabbit) | IC50 | 4.0000 | 1 | 1 |
| oc000459 | Oryctolagus cuniculus (rabbit) | IC50 | 15.0030 | 2 | 2 |
| mk-7246 | Oryctolagus cuniculus (rabbit) | IC50 | 2.5030 | 2 | 2 |