A nuclear receptor subfamily 1 group I member 2 that is encoded in the genome of rat. [OMA:Q9R1A7, PRO:DNx]
Orphan nuclear receptor PXR;
Pregnane X receptor
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| famprofazone | Rattus norvegicus (Norway rat) | EC50 | 9.8000 | 1 | 1 |
| felodipine | Rattus norvegicus (Norway rat) | EC50 | 23.4000 | 1 | 1 |
| fenbendazole | Rattus norvegicus (Norway rat) | EC50 | 4.0000 | 1 | 1 |
| nilvadipine | Rattus norvegicus (Norway rat) | EC50 | 10.5000 | 1 | 1 |
| nisoldipine | Rattus norvegicus (Norway rat) | EC50 | 31.6000 | 1 | 1 |
| oxatomide | Rattus norvegicus (Norway rat) | EC50 | 25.1000 | 1 | 1 |
| vorinostat | Rattus norvegicus (Norway rat) | EC50 | 2.5000 | 1 | 1 |
| ici 204,219 | Rattus norvegicus (Norway rat) | EC50 | 58.4000 | 1 | 1 |
| methylprednisolone | Rattus norvegicus (Norway rat) | EC50 | 4.0000 | 1 | 1 |
| hydralazine hydrochloride | Rattus norvegicus (Norway rat) | EC50 | 0.4500 | 1 | 1 |
| fluorometholone | Rattus norvegicus (Norway rat) | EC50 | 0.4000 | 1 | 1 |
| dinaline | Rattus norvegicus (Norway rat) | EC50 | 12.6000 | 1 | 1 |
| colforsin | Rattus norvegicus (Norway rat) | EC50 | 7.1000 | 1 | 1 |
| proadifen hydrochloride | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 1 | 1 |
| bumecain | Rattus norvegicus (Norway rat) | EC50 | 38.0000 | 1 | 1 |
| ryodipine | Rattus norvegicus (Norway rat) | EC50 | 1.8000 | 1 | 1 |
| droxidopa | Rattus norvegicus (Norway rat) | EC50 | 63.1000 | 1 | 1 |
| demecolcine | Rattus norvegicus (Norway rat) | EC50 | 0.0900 | 1 | 1 |
| epinastine | Rattus norvegicus (Norway rat) | EC50 | 4.5000 | 1 | 1 |
| terconazole | Rattus norvegicus (Norway rat) | EC50 | 9.1000 | 1 | 1 |
| carubicin | Rattus norvegicus (Norway rat) | EC50 | 2.8000 | 1 | 1 |
| epothilone b | Rattus norvegicus (Norway rat) | EC50 | 0.0100 | 1 | 1 |
| diclazuril | Rattus norvegicus (Norway rat) | EC50 | 9.0000 | 1 | 1 |
| zeranol | Rattus norvegicus (Norway rat) | EC50 | 38.4000 | 1 | 1 |
| desoximetasone | Rattus norvegicus (Norway rat) | EC50 | 10.0000 | 1 | 1 |
| rimexolone | Rattus norvegicus (Norway rat) | EC50 | 0.6800 | 1 | 1 |
| febantel | Rattus norvegicus (Norway rat) | EC50 | 31.6000 | 1 | 1 |