3'-methoxypuerarin: inhibits formation of advanced glycation end products; isolated from Pueraria lobata; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Pueraria | genus | A plant genus of the family FABACEAE a common weed of the southeast US. There has been folk use for alcoholism and liver protection. It contains puerarin, kakkalide, daidzein (isoflavonoids), and kudzusaponins (oleanene-type triterpene glycosides).[MeSH] | Fabaceae | The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of beans belong to this family.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 5319485 |
| CHEMBL ID | 3902210 |
| SCHEMBL ID | 8582185 |
| MeSH ID | M0506899 |
| Synonym |
|---|
| 3'-methoxypuerarin |
| 7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-8-[(2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one |
| SCHEMBL8582185 |
| 117047-07-1 |
| AC-34376 |
| 3-methoxy puerarin |
| Q-100079 |
| (8-beta-d-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-4h-1-benzopyran-4-one) |
| CHEMBL3902210 |
| CS-0018298 |
| HY-N1978 |
| 7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-8-((2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)-4h-chromen-4-one |
| AKOS030573599 |
| 3'- methoxy puerarin |
| 3 inverted exclamation mark - methoxy puerarin |
| puerariaglycoside 3 |
| 3 inverted exclamation mark -methoxy puerarin |
| MS-28051 |
| PD100425 |
| 3invertedexclamationmark-methoxypuerarin |
| Excerpt | Reference | Relevance |
|---|---|---|
| "A high-performance liquid chromatographic method was developed for the simultaneous determination and pharmacokinetic studies of safflor yellow A, puerarin, 3'-methoxyl-puerarin, and puerarinapioside in the plasma and tissues of rats that had been administered with the traditional Chinese medicine (TCM) preparation Naodesheng via the caudal vein." | ( HPLC determination of safflor yellow A and three active isoflavones from TCM Naodesheng in rat plasma and tissues and its application to pharmacokinetic studies. Bi, K; Gao, X; Yu, Z; Zhao, Y, 2007) | 0.34 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1317004 | Hepatoprotective activity against N-acetyl-p-aminophenol-induced cell injury in human HepG2 cells assessed as cell survival at 10 uM after 48 hrs by MTT assay (Rvb = 39.87%) | 2016 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 26, Issue:21 | Six new compounds from Atractylodes lancea and their hepatoprotective activities. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.36) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||