A cytochrome P450 2A that is a translation product of the Cyp2a5 gene in mouse. [PRO:DAN, UniProtKB:P20852]
EC 1.14.14.1;
CYPIIA5;
Coumarin 7-hydroxylase;
Cytochrome P450-15-COH;
Cytochrome P450-IIA3.2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| benzaldehyde | Mus musculus (house mouse) | IC50 | 3.2800 | 1 | 1 |
| naphthalene | Mus musculus (house mouse) | IC50 | 73.9802 | 2 | 2 |
| phenanthrene | Mus musculus (house mouse) | IC50 | 26.0008 | 2 | 2 |
| phenethylamine | Mus musculus (house mouse) | IC50 | 3.0000 | 1 | 1 |
| amphetamine | Mus musculus (house mouse) | IC50 | 2.8500 | 1 | 1 |
| 4-dichlorobenzene | Mus musculus (house mouse) | IC50 | 1.0000 | 2 | 2 |
| 1-methylnaphthalene | Mus musculus (house mouse) | IC50 | 23.9941 | 2 | 2 |
| 1-chloronaphthalene | Mus musculus (house mouse) | IC50 | 13.9980 | 2 | 2 |
| 1-naphthol | Mus musculus (house mouse) | IC50 | 139.9795 | 2 | 2 |
| 2-methylnaphthalene | Mus musculus (house mouse) | IC50 | 6.9992 | 2 | 2 |
| 2-chloronaphthalene | Mus musculus (house mouse) | IC50 | 11.9975 | 2 | 2 |
| 2-methylquinoline | Mus musculus (house mouse) | IC50 | 79.9917 | 2 | 2 |
| 2-methoxynaphthalene | Mus musculus (house mouse) | IC50 | 4.6013 | 2 | 2 |
| 4-methylbenzaldehyde | Mus musculus (house mouse) | IC50 | 4.6800 | 1 | 1 |
| 1,4-dibromobenzene | Mus musculus (house mouse) | IC50 | 2.1989 | 2 | 2 |
| 2-naphthol | Mus musculus (house mouse) | IC50 | 77.9915 | 2 | 2 |
| 1,2-dimethylnaphthalene | Mus musculus (house mouse) | IC50 | 23.9941 | 2 | 2 |
| 1,6-dimethylnaphthalene | Mus musculus (house mouse) | IC50 | 31.9944 | 2 | 2 |
| 2,6-dimethylnaphthalene | Mus musculus (house mouse) | IC50 | 1.6991 | 2 | 2 |
| 3-methylquinoline | Mus musculus (house mouse) | IC50 | 100.0000 | 2 | 2 |
| 2,6-dimethylquinoline | Mus musculus (house mouse) | IC50 | 39.9972 | 2 | 2 |
| 1-methylisoquinoline | Mus musculus (house mouse) | IC50 | 169.9120 | 2 | 2 |
| 4-chlorobiphenyl | Mus musculus (house mouse) | IC50 | 15.5008 | 2 | 2 |
| 4-anisaldehyde | Mus musculus (house mouse) | IC50 | 5.2300 | 1 | 1 |
| beta-tetralone | Mus musculus (house mouse) | IC50 | 9.7025 | 2 | 2 |
| nicotine | Mus musculus (house mouse) | IC50 | 159.9560 | 1 | 1 |
| pseudonicotine | Mus musculus (house mouse) | IC50 | 160.0000 | 1 | 1 |
| 2-chlorobiphenyl | Mus musculus (house mouse) | IC50 | 13.0008 | 2 | 2 |
| cotinine | Mus musculus (house mouse) | IC50 | 1,500.0000 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| coumarin | Mus musculus (house mouse) | Km | 0.6400 | 1 | 1 |