A free fatty acid receptor 2 that is encoded in the genome of human. [PRO:WCB, UniProtKB:O15552]
| Target | Category | Definition |
|---|
| leukocyte chemotaxis involved in inflammatory response | biological process | The movement of an immune cell in response to an external stimulus contributing to an inflammatory response. [GOC:add, ISBN:0781735149] |
| mucosal immune response | biological process | An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract. [GO_REF:0000022, GOC:jal, ISBN:0781735149] |
| regulation of acute inflammatory response | biological process | Any process that modulates the frequency, rate, or extent of an acute inflammatory response. [GOC:add] |
| positive regulation of cytokine production involved in immune response | biological process | Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. [GOC:add] |
| cell surface pattern recognition receptor signaling pathway | biological process | The series of molecular signals initiated by a ligand binding to a cell surface pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. [GOC:add, GOC:ar, ISBN:0781735149, PMID:15199967] |
| positive regulation of acute inflammatory response to non-antigenic stimulus | biological process | Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. [GOC:add] |
| G protein-coupled receptor signaling pathway | biological process | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor] |
| phospholipase C-activating G protein-coupled receptor signaling pathway | biological process | A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194] |
| lipid storage | biological process | The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. [GOC:dph, GOC:mah, GOC:tb, PMID:11102830] |
| positive regulation of insulin secretion | biological process | Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. [GOC:mah] |
| positive regulation of chemokine production | biological process | Any process that activates or increases the frequency, rate, or extent of chemokine production. [GOC:mah] |
| positive regulation of interleukin-8 production | biological process | Any process that activates or increases the frequency, rate, or extent of interleukin-8 production. [GOC:mah] |
| glucose homeostasis | biological process | Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. [GOC:go_curators] |
| fat cell differentiation | biological process | The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. [CL:0000136, GOC:go_curators] |
| negative regulation of insulin secretion | biological process | Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin. [GOC:ai] |
| cellular response to fatty acid | biological process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. [GOC:mah] |
| regulation of peptide hormone secretion | biological process | Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. [GOC:tb] |
| ligand-gated ion channel signaling pathway | biological process | The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription. [GOC:bhm, PMID:25869137] |