Page last updated: 2024-11-08

2-methoxy-2,4-diphenyl-3(2h)-furanone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-methoxy-2,4-diphenyl-3(2H)-furanone: reagent for fluorescent labeling of proteins; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID170874
SCHEMBL ID357523
MeSH IDM0052218

Synonyms (24)

Synonym
2-mdpf
FT-0639919
M0722
2-methoxy-2,4-diphenyl-3(2h)-furanone
50632-57-0
2-methoxy-2,4-diphenylfuran-3-one
3(2h)-furanone, 2-methoxy-2,4-diphenyl-
3(2h)-furanone,2-methoxy-2,4-diphenyl-
AKOS015912811
SCHEMBL357523
2-methoxy-2,4-diphenylfuran-3(2h)-one
mfcd00036834
2-methoxy-2,4-diphenyl-3-(2h)-furanone
2-methoxy-2,4-diphenyl-3(2h)-furanone, suitable for fluorescence, >=98.0% (hplc)
AS-63201
2-methoxy-2,4-diphenyl-2,3-dihydrofuran-3-one
methanesulfonicacidsodiumsalt
BLWINLJDTOJSRU-UHFFFAOYSA-N
DTXSID70964867
T72537
mdpf
A871495
CS-0323031
HY-W277900

Research Excerpts

Compound-Compound Interactions

ExcerptReferenceRelevance
"Three-color fluorescence detection methods are described based upon covalently coupling the dye 2-methoxy-2,4-diphenyl-2(2H)-furanone (MDPF) to proteins immobilized on poly(vinylidene difluoride) (PVDF) membranes, followed by detection of target proteins using alkaline-phosphatase-conjugated reporter molecules in combination with the fluorogenic substrate 9H-(1,3-dichloro-9,9-dimethylacridin-2-one-7-yl) phosphate (DDAO-phosphate) as well as horseradish peroxidase-conjugated reporter molecules in combination with the new fluorogenic substrate Amplex Gold reagent."( Simultaneous trichromatic fluorescence detection of proteins on Western blots using an amine-reactive dye in combination with alkaline phosphatase- and horseradish peroxidase-antibody conjugates.
Hart, C; Leung, WY; Liu, J; Martin, K; Patton, WF, 2003
)
0.32
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (31.58)18.7374
1990's6 (31.58)18.2507
2000's5 (26.32)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.31

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.31 (24.57)
Research Supply Index3.00 (2.92)
Research Growth Index4.31 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.31)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (5.26%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other18 (94.74%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]